lymphatic system cancer - Ontology Report - Rat Genome Database

Submit Data | Help | Video Tutorials | News | Publications | Download | REST API | Citing RGD | Contact

Advanced Search (OLGA)

RGD DISEASE ONTOLOGY - ANNOTATIONS

{{ watchLinkText }}

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:	lymphatic system cancer	go back to main search page
Accession:	DOID:0060073	browse the term
Definition:	An immune system cancer that is located_in the lymphatic system and is characterized by uncontrolled cellular proliferation of lymphoid tissue. (DO)

show annotations for term's descendants Sort by:
Rat (698) Mouse (1043) Human (5354) Chinchilla (588) Bonobo (623) Dog (638) Squirrel (594) Pig (626) Green Monkey (612) Naked Mole-rat (580) All
Genes (643) Cell Lines (400)

acute biphenotypic leukemia

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

DOT1 like histone lysine methyltransferase

treatment

RGD

NCBI chr10:80,590,935...80,631,295
Ensembl chr10:80,591,040...80,631,295

G

ring finger protein 20

disease_progression

RGD

NCBI chr 4:49,632,005...49,656,887
Ensembl chr 4:49,632,006...49,656,887

acute leukemia

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

excision repair cross-complementing rodent repair deficiency, complementation group 2

ClinVar Annotator: match by term: Mixed Phenotype Acute Leukemia, T/Myeloid, Not Otherwise Specified

PMID:7585650 PMID:8571952 PMID:9195225 PMID:9238033 PMID:15982307 More...

NCBI chr 7:19,115,942...19,129,619
Ensembl chr 7:19,115,935...19,129,619

acute lymphoblastic leukemia

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP-binding cassette, sub-family B member 1A

susceptibility

DNA:snps, haplotype:multiple (human)
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:22674224 PMID:22674224

NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575

G

ATP-binding cassette, sub-family member 2

treatment

DNA:SNP:5'UTR:rs717620(human)
DNA:SNPs: :rs717620(human)

RGD

PMID:24404132 PMID:25007187

RGD:11080959, RGD:11080979

NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179

G

ATP binding cassette subfamily G member 2 (Junior blood group)

disease_progression

mRNA:increased expression:mononuclear cell:

RGD

PMID:15521915 PMID:12100141

RGD:11081076, RGD:11081143

NCBI chr 6:58,561,476...58,669,436
Ensembl chr 6:58,561,508...58,672,661

G

c-abl oncogene 1, non-receptor tyrosine kinase

CTD Direct Evidence: marker/mechanism

PMID:11984797 PMID:21898527

NCBI chr 2:31,578,256...31,697,105
Ensembl chr 2:31,578,388...31,694,239

G

ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase

susceptibility

RGD

NCBI chr 2:26,732,508...26,754,973
Ensembl chr 2:26,732,515...26,754,991

G

activation-induced cytidine deaminase

treatment

RGD

NCBI chr 6:122,530,768...122,541,139
Ensembl chr 6:122,530,760...122,541,139

G

AT-rich interaction domain 5B

CTD Direct Evidence: marker/mechanism

PMID:19684603 PMID:19684604

NCBI chr10:67,928,353...68,114,596
Ensembl chr10:67,928,350...68,114,570

G

aryl hydrocarbon receptor nuclear translocator

CTD Direct Evidence: marker/mechanism

NCBI chr 3:95,341,674...95,404,551
Ensembl chr 3:95,341,699...95,404,551

G

BCL2-associated X protein

CTD Direct Evidence: marker/mechanism

NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322

G

B cell leukemia/lymphoma 2

severity

mRNA:increased expression:bone marrow (human)

RGD

NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004

G

BCL2-like 1

treatment

mRNA:increased expression:blood, mononuclear cell (human)

RGD

PMID:12469194 PMID:19020783

RGD:11353852, RGD:11353866

NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648

G

BCR activator of RhoGEF and GTPase

CTD Direct Evidence: marker/mechanism

NCBI chr10:74,896,384...75,020,753
Ensembl chr10:74,896,424...75,020,753

G

caspase 8

CTD Direct Evidence: therapeutic

NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662

G

calpastatin

protein:increased expresssion:B cell

RGD

NCBI chr13:74,840,485...74,956,993
Ensembl chr13:74,840,487...74,956,929

G

cyclin D1

mRNA:increased expression:bone marrow (human)

RGD

NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662

G

CD40 ligand

RGD

NCBI chr X:56,257,448...56,269,402
Ensembl chr X:56,257,503...56,269,402

G

CD46 antigen, complement regulatory protein

protein:increased expression:peripheral blood mononuclear cell (human)

RGD

NCBI chr 1:194,721,279...194,781,149
Ensembl chr 1:194,719,134...194,774,557

G

CD79B antigen

protein:decreased expression:bone marrow, mononuclear cell (human)

RGD

NCBI chr11:106,202,167...106,205,388
Ensembl chr11:106,202,167...106,205,588

G

CD86 antigen

severity

protein:increased expression:peripheral blood, bone marrow, mononuclear cell (human)

RGD

NCBI chr16:36,389,318...36,486,439
Ensembl chr16:36,424,231...36,486,443

G

cyclin dependent kinase 6

CTD Direct Evidence: marker/mechanism

NCBI chr 5:3,391,004...3,581,008
Ensembl chr 5:3,391,485...3,581,008

G

cyclin dependent kinase inhibitor 2A

disease_progression
no_association
susceptibility

DNA:deletion: :
DNA:missense mutations:cds:
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Acute lymphocytic leukemia | ClinVar Annotator: match by term: Acute lymphoid leukemia

CTD
ClinVar
RGD

PMID:7566978 PMID:7647780 PMID:7718873 PMID:7987387 PMID:8573142 More...

RGD:11251764, RGD:11252081, RGD:11252082, RGD:11057958

NCBI chr 4:89,192,710...89,212,856
Ensembl chr 4:89,192,708...89,212,890

G

cyclin dependent kinase inhibitor 2B

ClinVar Annotator: match by term: Acute lymphoid leukemia

NCBI chr 4:89,224,526...89,229,269
Ensembl chr 4:89,224,536...89,229,276

G

CCAAT/enhancer binding protein epsilon

CTD Direct Evidence: marker/mechanism

NCBI chr14:54,947,823...54,949,604
Ensembl chr14:54,947,817...54,949,631

G

complement factor B

DNA:missense mutation:p.R32Q b(human)

RGD

NCBI chr17:35,075,350...35,081,492
Ensembl chr17:35,075,350...35,081,494

G

CREB binding protein

disease_progression

DNA:mutations:multiple

RGD

NCBI chr16:3,899,198...4,031,864
Ensembl chr16:3,899,192...4,031,861

G

cytokine receptor-like factor 2

CTD Direct Evidence: marker/mechanism

NCBI chr 5:109,702,575...109,707,301
Ensembl chr 5:109,702,575...109,706,859

G

colony stimulating factor 3 (granulocyte)

treatment

RGD

NCBI chr11:98,591,287...98,594,457
Ensembl chr11:98,592,089...98,594,455

G

chondroitin sulfate proteoglycan 4

severity

RGD

NCBI chr 9:56,772,388...56,807,154
Ensembl chr 9:56,772,317...56,807,154

G

cytochrome b-245, alpha polypeptide

mRNA:increased expression:peripheral blood mononuclear cell:

RGD

NCBI chr 8:123,151,510...123,159,679
Ensembl chr 8:123,151,515...123,159,669

G

cytochrome P450, family 1, subfamily a, polypeptide 1

susceptibility
no_association

DNA:polymorphism:3"UTR:rs4646903(human)
DNA:polymorphism:cds:2452C>A(p.T461N)(human)
DNA:polymorphism:3'UTR:3801T>C(human)

RGD

PMID:22964275 PMID:23725389 PMID:16676594

RGD:11352714, RGD:11352725, RGD:11352728

NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107

G

cytochrome P450, family 1, subfamily a, polypeptide 2

CTD Direct Evidence: marker/mechanism

NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986

G

cytochrome P450, family 1, subfamily b, polypeptide 1

CTD Direct Evidence: marker/mechanism

NCBI chr17:80,014,369...80,022,490
Ensembl chr17:80,008,966...80,022,490

G

cytochrome P450, family 2, subfamily c, polypeptide 29

CTD Direct Evidence: marker/mechanism

NCBI chr19:39,275,541...39,319,157
Ensembl chr19:39,257,849...39,319,157

G

cytochrome P450, family 2, subfamily d, polypeptide 22

susceptibility

DNA:polymorphisms: :
DNA:SNP,deletion:splice junction,exon:1934G>A(human)

RGD

PMID:11037802 PMID:19593802

RGD:11352820, RGD:11252111

NCBI chr15:82,254,728...82,264,461
Ensembl chr15:82,254,728...82,264,461

G

cytochrome P450, family 2, subfamily e, polypeptide 1

CTD Direct Evidence: marker/mechanism

NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900

G

cytochrome P450, family 3, subfamily a, polypeptide 13

disease_progression
susceptibility

DNA:polymorphism: :

RGD

PMID:19650988 PMID:22215203

RGD:11353796, RGD:11353805

NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881

G

dihydrofolate reductase

disease_progression

DNA:polymorphisms, haplotype:promoter:
DNA:polymorphisms: :-317A>G, 829C>T (human)

RGD

PMID:19861437 PMID:9226157 PMID:22969948 PMID:12972803

RGD:11039542, RGD:11039543, RGD:11039544, RGD:11039545

NCBI chr13:92,491,291...92,525,561
Ensembl chr13:92,491,234...92,525,561

G

DNA methyltransferase 3A

treatment

DNA:mutations:exon, intron:p.R882(human)

RGD

NCBI chr12:3,851,559...3,964,442
Ensembl chr12:3,856,007...3,964,443

G

deoxynucleotidyltransferase, terminal

protein:increased activity:peripheral blood,bone marrow:

RGD

NCBI chr19:41,017,701...41,047,964
Ensembl chr19:41,017,714...41,047,964

G

dihydropyrimidine dehydrogenase

no_association
disease_progression

DNA:SNP: :85T>C (human)
DNA:SNPs: :2194G>A, 1156G>T (human)
DNA:splice-site mutation:intron:IVS14+1G>A (human)

RGD

PMID:26846104 PMID:26846104 PMID:26846104

RGD:11098453, RGD:11098453, RGD:11098453

NCBI chr 3:118,355,758...119,226,573
Ensembl chr 3:118,355,778...119,226,573

G

double homeobox B-like 1

CTD Direct Evidence: marker/mechanism

NCBI chr14:25,979,011...25,990,590
Ensembl chr14:25,979,001...25,990,512

G

euchromatic histone methyltransferase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 2:24,680,781...24,809,658
Ensembl chr 2:24,679,940...24,809,626

G

euchromatic histone lysine N-methyltransferase 2

CTD Direct Evidence: marker/mechanism

NCBI chr17:35,117,427...35,133,049
Ensembl chr17:35,117,445...35,133,028

G

endoglin

disease_progression

RGD

NCBI chr 2:32,536,607...32,572,681
Ensembl chr 2:32,536,607...32,572,681

G

epoxide hydrolase 1, microsomal

susceptibility
no_association

DNA:missense mutation, haplotype:exon:p.Y113H (human)
DNA:missense mutation, haplotype:exon:p.H139R (human)
DNA:polymorphisms:exon
DNA:SNPs:exon:rs1051740, rs2234922 (human)
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:21983886 PMID:21983886 PMID:21983886 PMID:19593802 PMID:22930568 More...

RGD:11252110, RGD:11252110, RGD:11252111, RGD:11252113, RGD:11252114

NCBI chr 1:180,817,121...180,845,134
Ensembl chr 1:180,803,775...180,848,469

G

excision repair cross-complementing rodent repair deficiency, complementation group 1

susceptibility

DNA:SNPs: :8092C>A, 19007G>A (human)
DNA:SNPs, haplotypes: :p.R194W, p.R280H, p.R399Q (human)

RGD

PMID:16723154 PMID:16435384

RGD:11252160, RGD:11340204

NCBI chr 7:19,079,016...19,090,449
Ensembl chr 7:19,078,703...19,090,449

G

excision repair cross-complementing rodent repair deficiency, complementation group 2

no_association

DNA:missense mutations: :p.D312N, p.K751Q (human)
DNA:haplotype

RGD

PMID:19101034 PMID:21987080

RGD:11252192, RGD:11340201

NCBI chr 7:19,115,942...19,129,619
Ensembl chr 7:19,115,935...19,129,619

G

ETS transcription factor

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Acute lymphoid leukemia

PMID:27776115 PMID:27993330

NCBI chr16:95,160,028...95,387,452
Ensembl chr16:95,160,028...95,387,452

G

ets variant 6

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Acute lymphoid leukemia

PMID:17255265 PMID:26102509

NCBI chr 6:134,012,663...134,247,121
Ensembl chr 6:134,012,663...134,247,121

G

enhancer of zeste 2 polycomb repressive complex 2 subunit

OMIM:247640 | OMIM:613065 | OMIM:613067 | OMIM:615545

NCBI chr 6:47,507,208...47,613,843
Ensembl chr 6:47,507,073...47,572,275

G

coagulation factor III

RGD

NCBI chr 3:121,517,186...121,528,701
Ensembl chr 3:121,517,186...121,528,697

G

Fas cell surface death receptor

disease_progression

protein:increased expression:CD34+ bone marrow cell

RGD

PMID:10500800 PMID:9711907

RGD:11049148, RGD:11049157

NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172

G

fibrinogen alpha chain

protein:increased expression:serum (human)

RGD

NCBI chr 3:82,933,460...82,940,934
Ensembl chr 3:82,933,383...82,940,934

G

FMS-like tyrosine kinase 3

ClinVar Annotator: match by term: Acute lymphoid leukemia
CTD Direct Evidence: marker/mechanism

ClinVar
CTD
OMIM

PMID:11290608 PMID:11442493 PMID:14604974 PMID:14670924 PMID:15256420 More...

NCBI chr 5:147,267,551...147,337,299
Ensembl chr 5:147,267,551...147,337,299

G

folylpolyglutamyl synthetase

CTD Direct Evidence: marker/mechanism

NCBI chr 2:32,572,621...32,594,163
Ensembl chr 2:32,572,621...32,594,157

G

GATA binding protein 3

CTD Direct Evidence: marker/mechanism

NCBI chr 2:9,861,889...9,894,845
Ensembl chr 2:9,861,889...9,894,845

G

growth factor independent 1B

mRNA:increased expression:blood:

RGD

NCBI chr 2:28,499,462...28,511,994
Ensembl chr 2:28,499,462...28,511,994

G

growth hormone

treatment

RGD

NCBI chr11:106,191,087...106,194,529
Ensembl chr11:106,191,097...106,192,691

G

guanine nucleotide binding protein (G protein), beta 1

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Acute lymphoblastic leukemia | ClinVar Annotator: match by term: Acute lymphoid leukemia | ClinVar Annotator: match by term: Lymphoblastic leukemia

OMIM
CTD
ClinVar

PMID:25485910 PMID:25741868 PMID:27108799 PMID:28492532 PMID:32134617 More...

NCBI chr 4:155,575,514...155,643,726
Ensembl chr 4:155,575,818...155,643,726

G

glucose-6-phosphate isomerase 1

RGD

NCBI chr 7:33,900,752...33,929,761
Ensembl chr 7:33,900,755...33,929,761

G

glutathione peroxidase 1

treatment

RGD

PMID:17317918 PMID:24698347

RGD:11352774, RGD:11352812

NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542

G

glutathione reductase

RGD

NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191

G

glutathione S-transferase, mu 1

disease_progression
susceptibility
no_association

RGD

PMID:10666194 PMID:15738600 PMID:12827651 PMID:14607752

RGD:10450829, RGD:10755321, RGD:10755409, RGD:10755410

NCBI chr 3:107,919,566...107,925,289
Ensembl chr 3:107,919,571...107,925,289

G

glutathione S-transferase, pi 1

disease_progression
no_association
susceptibility

DNA:haplotype:cds:
DNA:polymorphism: :1578 a>G(human)
DNA:transition mutation:exon:

RGD

PMID:10666194 PMID:23979883 PMID:15738600

RGD:10450829, RGD:10755417, RGD:10755321

NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985

G

glutathione S-transferase, theta 1

disease_progression
susceptibility

RGD

PMID:10666194 PMID:14607752

RGD:10450829, RGD:10755410

NCBI chr10:75,619,647...75,634,418
Ensembl chr10:75,619,647...75,634,418

G

H1.2 linker histone, cluster member

susceptibility

DNA:SNP, haplotype:enhancer: (rs807212) (human)

RGD

NCBI chr13:23,922,790...23,923,514
Ensembl chr13:23,922,791...23,924,350

G

histocompatibility 2, class II antigen A, alpha

DNA:polymorphisms, haplotype:cds:HLA-DQA1*01 (human)

RGD

NCBI chr17:34,501,718...34,506,797
Ensembl chr17:34,501,718...34,506,797

G

histocompatibility 2, class II antigen A, beta 1

DNA:polymorphisms, haplotypes:cds:multiple
DNA:polymorphisms, haplotype:cds:HLA-DQB1*0501 (human)

RGD

PMID:22434102 PMID:9744491

RGD:11041749, RGD:11041762

NCBI chr17:34,482,201...34,488,392
Ensembl chr17:34,476,663...34,488,393

G

hemopoietic cell kinase

CTD Direct Evidence: marker/mechanism

NCBI chr 2:152,950,388...152,993,361
Ensembl chr 2:152,950,388...152,993,361

G

histone deacetylase 1

disease_progression

mRNA:increased expression:bone marrow,blood:

RGD

NCBI chr 4:129,409,897...129,436,516
Ensembl chr 4:129,409,897...129,436,506

G

histone deacetylase 2

disease_progression

mRNA:increased expression:bone marrow,blood:

RGD

NCBI chr10:36,850,293...36,877,885
Ensembl chr10:36,850,540...36,877,885

G

histone deacetylase 4

treatment

RGD

NCBI chr 1:91,856,501...92,123,424
Ensembl chr 1:91,856,501...92,123,421

G

homeostatic iron regulator

no_association

DNA:missense mutation:cds:p.H63D (human)
DNA:missense mutation:cds:p.C282Y (human)
DNA:missense mutation: :p.H63D (human)

RGD

PMID:10627122 PMID:10627122 PMID:17107905

RGD:10755557, RGD:10755557, RGD:10755558

NCBI chr13:23,886,017...23,894,837
Ensembl chr13:23,886,017...23,894,837

G

hexokinase 1

protein:decreased activity:platelet

RGD

NCBI chr10:62,104,634...62,215,699
Ensembl chr10:62,104,634...62,215,687

G

hepatic leukemia factor

CTD Direct Evidence: marker/mechanism

NCBI chr11:90,227,361...90,281,745
Ensembl chr11:90,227,362...90,281,721

G

homeobox D4

ClinVar Annotator: match by term: Leukemia, acute lymphoblastic, susceptibility to
CTD Direct Evidence: marker/mechanism

NCBI chr 2:74,552,322...74,559,504
Ensembl chr 2:74,542,273...74,559,504

G

isocitrate dehydrogenase 1 (NADP+), soluble

CTD Direct Evidence: marker/mechanism

NCBI chr 1:65,197,775...65,225,638
Ensembl chr 1:65,197,775...65,225,659

G

interferon gamma

susceptibility

DNA:SNP: :rs2069727(human)

RGD

NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797

G

IKAROS family zinc finger 1

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Acute lymphocytic leukemia | ClinVar Annotator: match by term: Acute lymphoid leukemia | ClinVar Annotator: match by term: Leukemia, acute lymphocytic, susceptibility to, 2
DNA:SNPs: (human)

CTD
ClinVar
RGD

PMID:19684604 PMID:25741868 PMID:27993330 PMID:28492532 PMID:24786325

NCBI chr11:11,634,970...11,722,930
Ensembl chr11:11,634,980...11,722,926

G

IKAROS family zinc finger 2

CTD Direct Evidence: marker/mechanism

NCBI chr 1:69,570,382...69,726,510
Ensembl chr 1:69,570,373...69,726,404

G

IKAROS family zinc finger 3

CTD Direct Evidence: marker/mechanism

NCBI chr11:98,355,436...98,437,157
Ensembl chr11:98,355,728...98,436,857

G

interleukin 10

treatment

protein:decreased expression:blood

RGD

PMID:21653647 PMID:15860861

RGD:11049158, RGD:11049169

NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711

G

interferon regulatory factor 4

DNA:SNP:intron:rs12203592 (human)

RGD

NCBI chr13:30,933,191...30,950,965
Ensembl chr13:30,933,209...30,950,959

G

inosine triphosphatase (nucleoside triphosphate pyrophosphatase)

treatment
no_association

DNA:SNPs:exon:94C>A, 138G>A (human)
DNA:SNP:intron

RGD

PMID:22009189 PMID:22009189

RGD:10766474, RGD:10766474

NCBI chr 2:130,506,702...130,523,534
Ensembl chr 2:130,509,530...130,523,534

G

lysine (K)-specific demethylase 2B

mRNA:increased expression:bone marrow (human)

RGD

NCBI chr 5:123,008,727...123,127,333
Ensembl chr 5:123,008,728...123,127,886

G

KDM3B lysine (K)-specific demethylase 3B

protein:increased expression:bone marrow, mononuclear cell (human)

RGD

NCBI chr18:34,910,061...34,972,423
Ensembl chr18:34,910,100...34,971,713

G

lysine (K)-specific demethylase 6A

severity

DNA:mutations:cds:multiple (human)

RGD

NCBI chr X:18,027,101...18,147,061
Ensembl chr X:18,028,814...18,146,175

G

lysine (K)-specific methyltransferase 2A

OMIM:247640 | OMIM:613065 | OMIM:613067 | OMIM:615545
CTD Direct Evidence: marker/mechanism

PMID:24736461 PMID:25730765

NCBI chr 9:44,714,652...44,793,492
Ensembl chr 9:44,714,652...44,792,594

G

Kirsten rat sarcoma viral oncogene homolog

disease_progression

RGD

PMID:17910045 PMID:25917266

RGD:11060148, RGD:11060149

NCBI chr 6:145,162,425...145,197,631
Ensembl chr 6:145,162,425...145,195,965

G

LIM domain only 2

OMIM:247640 | OMIM:613065

NCBI chr 2:103,788,309...103,812,223
Ensembl chr 2:103,788,331...103,812,223

G

Mediterranean fever

susceptibility

DNA:polymorphisms:cds:p.E148Q,M680I(human)

RGD

NCBI chr16:3,524,838...3,536,073
Ensembl chr16:3,525,082...3,535,961

G

methylenetetrahydrofolate reductase

disease_progression
treatment

DNA:missense mutation:cds:677C>T (p.A222V) (rs1801133) (human)
CTD Direct Evidence: marker/mechanism
DNA:missense mutation:cds:677C>T (human)

CTD
RGD

PMID:16706930 PMID:19923983 PMID:21644011

RGD:10449398, RGD:10449407

NCBI chr 4:148,123,534...148,144,019
Ensembl chr 4:148,123,534...148,144,008

G

5-methyltetrahydrofolate-homocysteine methyltransferase

disease_progression
susceptibility
no_association

DNA:SNP::rs10925235(human)
DNA:polymorphism: :66A>G(human)
DNA:polymorphism: :2756A>G(human)

RGD

PMID:26605150 PMID:21618417 PMID:15159311 PMID:22453148

RGD:11531136, RGD:11531141, RGD:11531140, RGD:11531137

NCBI chr13:12,196,217...12,273,090
Ensembl chr13:12,197,598...12,272,999

G

5-methyltetrahydrofolate-homocysteine methyltransferase reductase

susceptibility

DNA:haplotype:cds:
CTD Direct Evidence: marker/mechanism
DNA:SNP: :rs3776455(human)

CTD
RGD

PMID:17136115 PMID:17136115 PMID:23940529

RGD:11531133, RGD:11531135

NCBI chr13:68,708,897...68,730,273
Ensembl chr13:68,708,899...68,730,268

G

myelocytomatosis oncogene

disease_progression

RGD

NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223

G

N-acetyltransferase 2 (arylamine N-acetyltransferase)

susceptibility
no_association

DNA:polymorphisms: :
DNA:polymorphisms,haplotype: :
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:22200898 PMID:25804798 PMID:21888617 PMID:22215203

RGD:11532767, RGD:11532769, RGD:11353805

NCBI chr 8:67,947,527...67,955,296
Ensembl chr 8:67,947,510...67,955,236

G

nibrin

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Acute lymphoblastic leukemia | ClinVar Annotator: match by term: Acute lymphocytic leukemia | ClinVar Annotator: match by term: Acute lymphoid leukemia | ClinVar Annotator: match by term: Lymphoblastic leukemia

OMIM
CTD
ClinVar

PMID:9590180 PMID:11325820 PMID:12353271 PMID:14559852 PMID:15338273 More...

NCBI chr 4:15,955,388...15,992,589
Ensembl chr 4:15,957,925...15,992,589

G

nitric oxide synthase 3, endothelial cell

susceptibility
disease_progression

DNA:SNP: :rs3918186(human)
DNA:polymorphism, haplotype:cds,intron:P.E298D,-786T>C(human)

RGD

PMID:23922896 PMID:20510681

RGD:11533639, RGD:11533646

NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472

G

notch 3

OMIM:247640 | OMIM:613065

NCBI chr17:32,339,794...32,385,869
Ensembl chr17:32,339,794...32,385,826

G

NAD(P)H dehydrogenase, quinone 1

DNA:mutation: :609C>T (human)
DNA:missense mutations: :p.R139W (465C>T), p.P187S (609C>T) (human)
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:11774269 PMID:17332311 PMID:18444911 PMID:11774269

RGD:10769347, RGD:10769359

NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838

G

neuroblastoma ras oncogene

disease_progression

DNA:missense mutation:cds:

RGD

NCBI chr 3:102,965,643...102,975,230
Ensembl chr 3:102,965,601...102,975,230

G

nuclear receptor binding SET domain protein 2

CTD Direct Evidence: therapeutic

NCBI chr 5:33,974,286...34,055,310
Ensembl chr 5:33,978,069...34,055,319

G

5'-nucleotidase, cytosolic II

CTD Direct Evidence: marker/mechanism

NCBI chr19:46,873,829...47,003,613
Ensembl chr19:46,871,756...47,003,592

G

nucleoporin 214

CTD Direct Evidence: marker/mechanism

NCBI chr 2:31,864,446...31,943,204
Ensembl chr 2:31,864,448...31,943,987

G

phosphoprotein associated with glycosphingolipid microdomains 1

CTD Direct Evidence: marker/mechanism

NCBI chr 3:9,752,539...9,898,744
Ensembl chr 3:9,752,539...9,898,739

G

paired box 5

susceptibility

ClinVar Annotator: match by term: Acute lymphoid leukemia | ClinVar Annotator: match by term: Leukemia, acute lymphoblastic, susceptibility to, 3
CTD Direct Evidence: marker/mechanism

OMIM
ClinVar
CTD

PMID:24013638 PMID:24728327 PMID:25741868 PMID:26214592 PMID:27993330 More...

NCBI chr 4:44,524,748...44,710,694
Ensembl chr 4:44,524,757...44,710,487

G

paraoxonase 1

susceptibility

DNA:missense mutations:cds:p.L55M (rs854560), p.Q192R (rs662) (human)

RGD

NCBI chr 6:5,168,101...5,193,824
Ensembl chr 6:5,168,090...5,193,946

G

PRAME like, X-linked 1

severity

mRNA:increased expression:blood (human)

RGD

NCBI chr X:134,513,662...134,528,437
Ensembl chr X:134,513,751...134,528,454

G

PR domain containing 14

CTD Direct Evidence: marker/mechanism

NCBI chr 1:13,183,649...13,197,467
Ensembl chr 1:13,183,681...13,197,387

G

phosphatase and tensin homolog

OMIM:247640 | OMIM:613065 | OMIM:613067 | OMIM:615545

NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560

G

RB transcriptional corepressor 1

CTD Direct Evidence: marker/mechanism

NCBI chr14:73,430,298...73,563,446
Ensembl chr14:73,421,113...73,563,262

G

runt related transcription factor 1

CTD Direct Evidence: marker/mechanism

NCBI chr16:92,398,354...92,622,962
Ensembl chr16:92,398,354...92,623,037

G

solute carrier family 19 (folate transporter), member 1

CTD Direct Evidence: marker/mechanism

NCBI chr10:76,868,103...76,886,266
Ensembl chr10:76,868,075...76,896,836

G

small nuclear ribonucleoprotein E

severity

mRNA:decreased expression:bone marrow, blood, mononuclear cell (human)

RGD

NCBI chr 1:133,531,609...133,538,018
Ensembl chr 1:133,531,609...133,538,029

G

T cell acute lymphocytic leukemia 1

CTD Direct Evidence: marker/mechanism

NCBI chr 4:114,913,623...114,928,952
Ensembl chr 4:114,913,623...114,928,952

G

T cell acute lymphocytic leukemia 2

CTD Direct Evidence: marker/mechanism

NCBI chr 4:53,779,701...53,788,712
Ensembl chr 4:53,779,705...53,788,712

G

taste receptor, type 2, member 103

CTD Direct Evidence: marker/mechanism

NCBI chr 6:133,013,126...133,014,064
Ensembl chr 6:133,013,126...133,014,064

G

transcription factor 3

CTD Direct Evidence: marker/mechanism

NCBI chr10:80,245,375...80,269,814
Ensembl chr10:80,245,348...80,269,481

G

transcobalamin 2

protein:altered activity:plasma:

RGD

NCBI chr11:3,867,077...3,882,078
Ensembl chr11:3,867,192...3,882,159

G

telomerase reverse transcriptase

DNA:SNPs:promoter, introns:g.1296486C>T, g.12866516A>C, g.1279790G>A (rs2735940, rs2736100, rs10069690) (human)

RGD

PMID:23066086 PMID:15621763

RGD:11038654, RGD:11038667

NCBI chr13:73,775,030...73,797,962
Ensembl chr13:73,775,030...73,797,962

G

transmembrane 9 superfamily member 2

mRNA:increased expression:bone marrow, mononuclear cells (human)

RGD

NCBI chr14:122,342,290...122,397,015
Ensembl chr14:122,344,450...122,397,016

G

thiopurine methyltransferase

treatment
no_association

DNA:SNPs:multiple
DNA:SNPs:introns:12356C>T, 16638C>T, 26354G>T (rs4449636, rs2518463, rs2842949) (human)
DNA:SNPs:exon:374C>T, 719A>G (rs2842934, rs1142345) (human)
DNA:SNPs: :multiple

RGD

PMID:17164697 PMID:22009189 PMID:22009189 PMID:24499706

RGD:11038720, RGD:10766474, RGD:10766474, RGD:11038723

NCBI chr13:47,175,463...47,196,833
Ensembl chr13:47,175,958...47,198,213

G

transformation related protein 53

CTD Direct Evidence: marker/mechanism

NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699

G

tetratricopeptide repeat domain 12

DNA:hypermethylation:5'end:CpG dinucleotide

RGD

NCBI chr 9:49,348,261...49,397,572
Ensembl chr 9:49,348,263...49,397,525

G

thymidylate synthase

treatment

DNA:repeats: : rs347430033(human)

RGD

NCBI chr 5:30,243,544...30,279,261
Ensembl chr 5:30,263,200...30,278,615

G

V-set pre-B cell surrogate light chain 1A

CTD Direct Evidence: marker/mechanism

NCBI chr16:16,686,265...16,687,119
Ensembl chr16:16,686,267...16,688,707

G

X-ray repair complementing defective repair in Chinese hamster cells 1

susceptibility
no_association

DNA:missense mutation, haplotype: :p.R399Q (human)
DNA:missense mutation: :p.R194W (human)
DNA:missense mutation: :p.R399Q (human)
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:21983886 PMID:21983886 PMID:19101034 PMID:19101034

RGD:11252110, RGD:11252192, RGD:11252192

NCBI chr 7:24,246,124...24,272,863
Ensembl chr 7:24,245,714...24,272,865

Acute Lymphoblastic Leukemia, with Lymphomatous Features

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

c-abl oncogene 1, non-receptor tyrosine kinase

ClinVar Annotator: match by term: Lymphoblastic leukemia, acute, with lymphomatous features

PMID:10988075 PMID:11423618 PMID:11853795 PMID:11861307 PMID:11964322 More...

NCBI chr 2:31,578,256...31,697,105
Ensembl chr 2:31,578,388...31,694,239

G

cytokine receptor-like factor 2

ClinVar Annotator: match by term: Lymphoblastic leukemia, acute, with lymphomatous features

PMID:19907440 PMID:19965641 PMID:20018760 PMID:22368272

NCBI chr 5:109,702,575...109,707,301
Ensembl chr 5:109,702,575...109,706,859

G

cytochrome P450, family 2, subfamily b, polypeptide 10

susceptibility

DNA:polymorphism:G15631T

NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049

G

fibroblast growth factor receptor 1

ClinVar Annotator: match by term: Lymphoblastic leukemia, acute, with lymphomatous features

PMID:25705862 PMID:26619011 PMID:26942290 PMID:33448156

NCBI chr 8:26,008,808...26,067,819
Ensembl chr 8:26,003,670...26,065,734

G

interleukin 7 receptor

ClinVar Annotator: match by term: Lymphoblastic leukemia, acute, with lymphomatous features

PMID:22897847 PMID:22955920

NCBI chr15:9,505,880...9,530,270
Ensembl chr15:9,505,874...9,530,262

G

insulin-like 6

ClinVar Annotator: match by term: Lymphoblastic leukemia, acute, with lymphomatous features

PMID:18805579 PMID:19470474 PMID:20585391 PMID:22368270 PMID:22955920

NCBI chr19:29,298,754...29,302,718
Ensembl chr19:29,298,744...29,302,756

G

Janus kinase 1

ClinVar Annotator: match by term: Lymphoblastic leukemia, acute, with lymphomatous features

PMID:16239216 PMID:19139102 PMID:19470474 PMID:19838194 PMID:20167706 More...

NCBI chr 4:101,009,171...101,122,493
Ensembl chr 4:101,009,564...101,122,479

G

Janus kinase 2

ClinVar Annotator: match by term: Lymphoblastic leukemia, acute, with lymphomatous features

PMID:18805579 PMID:19470474 PMID:20585391 PMID:22368270 PMID:22955920

NCBI chr19:29,229,006...29,290,495
Ensembl chr19:29,229,228...29,290,480

G

Janus kinase 3

ClinVar Annotator: match by term: LYMPHOMATOUS ALL

PMID:10982185 PMID:16843266 PMID:18270328 PMID:20132407 PMID:20372971 More...

NCBI chr 8:72,129,027...72,143,221
Ensembl chr 8:72,128,940...72,143,219

adenoid cystic carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

aquaporin 1

CTD Direct Evidence: marker/mechanism

NCBI chr 6:55,313,284...55,325,540
Ensembl chr 6:55,313,417...55,325,540

G

AT-rich interaction domain 1A

CTD Direct Evidence: marker/mechanism

NCBI chr 4:133,406,319...133,484,682
Ensembl chr 4:133,406,319...133,484,080

G

AT-rich interaction domain 2

ClinVar Annotator: match by term: Adenoid cystic carcinoma

NCBI chr15:96,185,403...96,303,344
Ensembl chr15:96,185,399...96,302,873

G

AT-rich interaction domain 4B

CTD Direct Evidence: marker/mechanism

NCBI chr13:14,238,334...14,374,188
Ensembl chr13:14,237,817...14,374,188

G

AT-rich interaction domain 5B

CTD Direct Evidence: marker/mechanism

NCBI chr10:67,928,353...68,114,596
Ensembl chr10:67,928,350...68,114,570

G

abnormal spindle microtubule assembly

CTD Direct Evidence: marker/mechanism

NCBI chr 1:139,381,450...139,421,826
Ensembl chr 1:139,382,510...139,421,829

G

ataxia telangiectasia mutated

CTD Direct Evidence: marker/mechanism

NCBI chr 9:53,348,422...53,448,125
Ensembl chr 9:53,350,449...53,448,040

G

ataxia telangiectasia and Rad3 related

treatment

RGD

NCBI chr 9:95,739,655...95,834,813
Ensembl chr 9:95,739,650...95,833,834

G

ATRX, chromatin remodeler

CTD Direct Evidence: marker/mechanism

NCBI chr X:104,841,221...104,972,978
Ensembl chr X:104,841,221...104,973,009

G

Brca1 associated protein 1

ClinVar Annotator: match by term: Adenocystic carcinoma | ClinVar Annotator: match by term: Adenoid cystic carcinoma

PMID:21642991 PMID:24894717 PMID:26166446 PMID:26452128 PMID:28492532

NCBI chr14:30,973,358...30,981,887
Ensembl chr14:30,973,407...30,981,901

G

BCL11 transcription factor A

CTD Direct Evidence: marker/mechanism

NCBI chr11:24,026,498...24,123,558
Ensembl chr11:24,028,056...24,124,123

G

BCL6 interacting corepressor

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Adenoid cystic carcinoma

NCBI chr X:11,902,976...12,026,769
Ensembl chr X:11,902,979...12,026,594

G

BCL6 co-repressor-like 1

CTD Direct Evidence: marker/mechanism

NCBI chr X:47,430,235...47,496,945
Ensembl chr X:47,430,235...47,496,926

G

breast cancer 1, early onset

CTD Direct Evidence: marker/mechanism

NCBI chr11:101,379,587...101,442,808
Ensembl chr11:101,379,590...101,442,781

G

bromodomain containing 1

CTD Direct Evidence: marker/mechanism

NCBI chr15:88,571,237...88,618,508
Ensembl chr15:88,571,237...88,618,436

G

cyclin D1

CTD Direct Evidence: marker/mechanism

NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662

G

cadherin 1

CTD Direct Evidence: marker/mechanism

NCBI chr 8:107,329,982...107,396,879
Ensembl chr 8:107,329,983...107,396,878

G

cap methyltransferase 2

CTD Direct Evidence: marker/mechanism

NCBI chr 8:110,941,977...110,951,121
Ensembl chr 8:110,942,297...110,951,118

G

contactin 6

CTD Direct Evidence: marker/mechanism

NCBI chr 6:104,469,566...104,840,367
Ensembl chr 6:104,469,751...104,840,367

G

CREB binding protein

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Adenocystic carcinoma

PMID:21390126 PMID:21680795 PMID:21796119 PMID:22832583 PMID:23334668 More...

NCBI chr16:3,899,198...4,031,864
Ensembl chr16:3,899,192...4,031,861

G

death associated protein kinase 1

CTD Direct Evidence: marker/mechanism

NCBI chr13:60,749,506...60,911,005
Ensembl chr13:60,749,761...60,911,005

G

denticleless E3 ubiquitin protein ligase

CTD Direct Evidence: marker/mechanism

NCBI chr 1:191,269,468...191,307,656
Ensembl chr 1:191,269,468...191,307,656

G

deltex 4, E3 ubiquitin ligase

CTD Direct Evidence: marker/mechanism

NCBI chr19:12,443,700...12,479,509
Ensembl chr19:12,443,702...12,478,818

G

EF hand domain containing 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:87,192,075...87,238,563
Ensembl chr 1:87,192,085...87,238,561

G

engrailed 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:120,530,246...120,535,719
Ensembl chr 1:120,530,147...120,535,721

G

E1A binding protein p300

CTD Direct Evidence: marker/mechanism

NCBI chr15:81,470,329...81,536,273
Ensembl chr15:81,469,552...81,536,278

G

Erbb2 interacting protein

CTD Direct Evidence: marker/mechanism

NCBI chr13:103,955,294...104,057,094
Ensembl chr13:103,955,295...104,057,022

G

extra spindle pole bodies 1, separase

CTD Direct Evidence: marker/mechanism

NCBI chr15:102,204,688...102,232,792
Ensembl chr15:102,204,701...102,232,792

G

Fanconi anemia, complementation group A

CTD Direct Evidence: marker/mechanism

NCBI chr 8:123,993,033...124,045,390
Ensembl chr 8:123,995,039...124,045,315

G

FAT atypical cadherin 1

CTD Direct Evidence: marker/mechanism

NCBI chr 8:45,386,137...45,505,294
Ensembl chr 8:45,388,484...45,505,294

G

F-box and WD-40 domain protein 7

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Adenocystic carcinoma

PMID:23685749 PMID:26619011

NCBI chr 3:84,721,901...84,886,505
Ensembl chr 3:84,722,575...84,886,505

G

fibroblast growth factor 16

CTD Direct Evidence: marker/mechanism

NCBI chr X:104,808,083...104,820,138
Ensembl chr X:104,807,885...104,818,545

G

fibroblast growth factor receptor 2

ClinVar Annotator: match by term: Adenoid cystic carcinoma

NCBI chr 7:129,764,181...129,868,538
Ensembl chr 7:129,764,181...132,725,079

G

fibroblast growth factor receptor 4

CTD Direct Evidence: marker/mechanism

NCBI chr13:55,300,631...55,316,572
Ensembl chr13:55,300,453...55,316,572

G

forkhead box O3

CTD Direct Evidence: marker/mechanism

NCBI chr10:42,057,841...42,152,691
Ensembl chr10:42,057,837...42,152,751

G

forkhead box P2

CTD Direct Evidence: marker/mechanism

NCBI chr 6:14,901,348...15,441,976
Ensembl chr 6:14,901,348...15,441,976

G

growth arrest specific 2

CTD Direct Evidence: marker/mechanism

NCBI chr 7:51,511,560...51,644,753
Ensembl chr 7:51,511,763...51,644,723

G

growth arrest specific 6

CTD Direct Evidence: marker/mechanism

NCBI chr 8:13,515,374...13,544,535
Ensembl chr 8:13,515,374...13,544,490

G

GINS complex subunit 2

CTD Direct Evidence: marker/mechanism

NCBI chr 8:121,308,005...121,315,814
Ensembl chr 8:121,305,372...121,316,043

G

guanylate cyclase 1, soluble, alpha 1

CTD Direct Evidence: marker/mechanism

NCBI chr 3:81,999,734...82,053,253
Ensembl chr 3:81,999,734...82,053,096

G

H1.4 linker histone, cluster member

CTD Direct Evidence: marker/mechanism

NCBI chr13:23,805,760...23,806,541
Ensembl chr13:23,804,612...23,806,541

G

H2A clustered histone 8

CTD Direct Evidence: marker/mechanism

NCBI chr13:23,754,837...23,755,394
Ensembl chr13:23,754,691...23,755,394

G

homer scaffolding protein 3

CTD Direct Evidence: marker/mechanism

NCBI chr 8:70,735,529...70,747,011
Ensembl chr 8:70,735,477...70,747,011

G

Harvey rat sarcoma virus oncogene

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Adenocystic carcinoma

PMID:11150980 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 More...

NCBI chr 7:140,770,839...140,773,938
Ensembl chr 7:140,769,018...140,773,918

G

isocitrate dehydrogenase 1 (NADP+), soluble

ClinVar Annotator: match by term: Adenocystic carcinoma

PMID:18772396 PMID:19657110 PMID:19798509 PMID:19818334 PMID:20946881 More...

NCBI chr 1:65,197,775...65,225,638
Ensembl chr 1:65,197,775...65,225,659

G

insulin-like growth factor binding protein 2

CTD Direct Evidence: marker/mechanism

NCBI chr 1:72,863,650...72,891,633
Ensembl chr 1:72,863,662...72,891,633

G

interleukin 17 receptor D

CTD Direct Evidence: marker/mechanism

NCBI chr14:26,760,990...26,829,243
Ensembl chr14:26,760,898...26,829,243

G

insulin receptor-related receptor

CTD Direct Evidence: marker/mechanism

NCBI chr 3:87,704,215...87,723,408
Ensembl chr 3:87,704,258...87,723,408

G

Iroquois homeobox 4

CTD Direct Evidence: marker/mechanism

NCBI chr13:73,407,708...73,417,741
Ensembl chr13:73,408,598...73,417,727

G

myo-inositol 1-phosphate synthase A1

CTD Direct Evidence: marker/mechanism

NCBI chr 8:71,047,131...71,049,940
Ensembl chr 8:71,047,023...71,049,940

G

integrin beta 4

CTD Direct Evidence: marker/mechanism

NCBI chr11:115,865,556...115,899,238
Ensembl chr11:115,865,535...115,899,238

G

jagged 1

CTD Direct Evidence: marker/mechanism

NCBI chr 2:136,923,371...136,958,440
Ensembl chr 2:136,923,376...136,958,564

G

Janus kinase 3

ClinVar Annotator: match by term: Adenocystic carcinoma

PMID:14615376 PMID:28492532 PMID:33040328

NCBI chr 8:72,129,027...72,143,221
Ensembl chr 8:72,128,940...72,143,219

G

jumonji domain containing 1C

CTD Direct Evidence: marker/mechanism

NCBI chr10:66,932,189...67,092,105
Ensembl chr10:66,931,904...67,092,105

G

KAT8 regulatory NSL complex subunit 1

CTD Direct Evidence: marker/mechanism

NCBI chr11:104,224,327...104,360,584
Ensembl chr11:104,224,055...104,359,687

G

K(lysine) acetyltransferase 6A

CTD Direct Evidence: marker/mechanism

NCBI chr 8:23,349,458...23,433,275
Ensembl chr 8:23,349,551...23,433,275

G

lysine (K)-specific demethylase 6A

exacerbates

CTD Direct Evidence: marker/mechanism
DNA:mutations:multiple: (human)
DNA:splice-site mutation, missense mutations:splice junction, CDS:multiple: (human)

CTD
RGD

PMID:23685749 PMID:31483290 PMID:23685749

RGD:150429736, RGD:150429732

NCBI chr X:18,027,101...18,147,061
Ensembl chr X:18,028,814...18,146,175

G

KDM1 lysine (K)-specific demethylase 6B

CTD Direct Evidence: marker/mechanism

NCBI chr11:69,289,334...69,311,188
Ensembl chr11:69,289,334...69,304,501

G

lysine (K)-specific methyltransferase 2C

disease_progression

CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:23685749 PMID:31483290

NCBI chr 5:25,476,793...25,703,853
Ensembl chr 5:25,476,796...25,703,781

G

Kirsten rat sarcoma viral oncogene homolog

ClinVar Annotator: match by term: Adenocystic carcinoma

PMID:6695174 PMID:12460918 PMID:15696205 PMID:16361624 PMID:16618717 More...

NCBI chr 6:145,162,425...145,197,631
Ensembl chr 6:145,162,425...145,195,965

G

keratin 15

CTD Direct Evidence: marker/mechanism

NCBI chr11:100,022,585...100,026,775
Ensembl chr11:100,022,584...100,026,754

G

keratin 5

CTD Direct Evidence: marker/mechanism

NCBI chr15:101,615,504...101,621,340
Ensembl chr15:101,615,505...101,621,333

G

leucine rich repeat containing 56

ClinVar Annotator: match by term: Adenocystic carcinoma

PMID:11150980 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 More...

NCBI chr 7:140,774,024...140,789,968
Ensembl chr 7:140,774,070...140,789,968

G

membrane associated guanylate kinase, WW and PDZ domain containing 1

CTD Direct Evidence: marker/mechanism

NCBI chr 6:93,652,434...94,260,906
Ensembl chr 6:93,652,436...94,260,898

G

membrane associated guanylate kinase, WW and PDZ domain containing 2

CTD Direct Evidence: marker/mechanism

NCBI chr 5:19,431,787...20,909,790
Ensembl chr 5:19,432,034...20,909,790

G

mastermind like transcriptional coactivator 3

CTD Direct Evidence: marker/mechanism

NCBI chr 3:51,595,032...52,012,740
Ensembl chr 3:51,593,328...52,012,497

G

mitogen-activated protein kinase kinase 2

CTD Direct Evidence: marker/mechanism

NCBI chr10:80,941,749...80,960,531
Ensembl chr10:80,941,749...80,969,809

G

myristoylated alanine rich protein kinase C substrate

CTD Direct Evidence: marker/mechanism

NCBI chr10:37,009,239...37,014,922
Ensembl chr10:37,009,371...37,014,916

G

MAP/microtubule affinity regulating kinase 2

CTD Direct Evidence: marker/mechanism

NCBI chr19:7,252,761...7,319,222
Ensembl chr19:7,252,761...7,319,225

G

MDS1 and EVI1 complex locus

ClinVar Annotator: match by term: Adenoid cystic carcinoma

NCBI chr 3:30,005,445...30,563,937
Ensembl chr 3:30,005,445...30,602,157

G

MAX gene associated

CTD Direct Evidence: marker/mechanism

NCBI chr 2:119,702,974...119,800,610
Ensembl chr 2:119,727,709...119,800,062

G

MIER family member 2

CTD Direct Evidence: marker/mechanism

NCBI chr10:79,376,079...79,395,229
Ensembl chr10:79,376,079...79,391,033

G

megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human)

CTD Direct Evidence: marker/mechanism

NCBI chr15:88,840,087...88,863,192
Ensembl chr15:88,840,087...88,863,210

G

mortality factor 4 like 1

CTD Direct Evidence: marker/mechanism

NCBI chr 9:89,973,722...89,996,873
Ensembl chr 9:89,973,718...89,996,827

G

myeloblastosis oncogene

CTD Direct Evidence: marker/mechanism

PMID:23685749 PMID:26829750

NCBI chr10:21,000,829...21,036,883
Ensembl chr10:21,000,834...21,036,883

G

myeloblastosis oncogene-like 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:9,737,632...9,770,664
Ensembl chr 1:9,737,640...9,770,434

G

MYC binding protein

CTD Direct Evidence: marker/mechanism

NCBI chr 4:123,798,806...123,806,043
Ensembl chr 4:123,798,625...123,806,062

G

v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived

CTD Direct Evidence: marker/mechanism

NCBI chr12:12,986,094...12,991,837
Ensembl chr12:12,986,094...12,991,915

G

neuropilin (NRP) and tolloid (TLL)-like 2

CTD Direct Evidence: marker/mechanism

NCBI chr 8:86,363,347...86,428,011
Ensembl chr 8:86,363,217...86,427,553

G

nuclear factor I/B

CTD Direct Evidence: marker/mechanism

NCBI chr 4:82,208,410...82,424,988
Ensembl chr 4:82,208,410...82,623,987

G

notch 1

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Adenoid cystic carcinoma

NCBI chr 2:26,347,914...26,393,834
Ensembl chr 2:26,347,915...26,406,675

G

nuclear receptor-binding SET-domain protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr13:55,357,595...55,466,138
Ensembl chr13:55,357,595...55,466,138

G

neurotrophic tyrosine kinase, receptor, type 3

treatment

RGD

NCBI chr 7:77,825,711...78,228,865
Ensembl chr 7:77,825,707...78,387,760

G

proprotein convertase subtilisin/kexin type 1 inhibitor

CTD Direct Evidence: marker/mechanism

NCBI chr X:7,786,061...7,790,649
Ensembl chr X:7,786,061...7,790,649

G

PDZ domain containing 1

CTD Direct Evidence: marker/mechanism

NCBI chr 3:96,736,772...96,778,242
Ensembl chr 3:96,736,600...96,778,242

G

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Adenocystic carcinoma

PMID:15930273 PMID:17376864 PMID:18074223 PMID:19366826 PMID:22120714 More...

NCBI chr 3:32,451,203...32,520,256
Ensembl chr 3:32,451,820...32,522,635

G

protein kinase, DNA activated, catalytic polypeptide

CTD Direct Evidence: marker/mechanism

NCBI chr16:15,455,698...15,660,103
Ensembl chr16:15,455,730...15,660,099

G

phosphatase and tensin homolog

CTD Direct Evidence: marker/mechanism

NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560

G

brain glycogen phosphorylase

CTD Direct Evidence: marker/mechanism

NCBI chr 2:150,628,716...150,673,668
Ensembl chr 2:150,628,655...150,673,678

G

RNA binding protein, fox-1 homolog (C. elegans) 2

CTD Direct Evidence: marker/mechanism

NCBI chr15:76,963,190...77,193,058
Ensembl chr15:76,963,190...77,191,204

G

serine (or cysteine) peptidase inhibitor, clade F, member 1

CTD Direct Evidence: marker/mechanism

NCBI chr11:75,300,855...75,313,449
Ensembl chr11:75,300,595...75,313,527

G

SET domain containing 2

CTD Direct Evidence: marker/mechanism

NCBI chr 9:110,361,368...110,447,703
Ensembl chr 9:110,361,665...110,447,701

G

splicing factor 3b, subunit 1

ClinVar Annotator: match by term: Adenoid cystic carcinoma

PMID:25741868 PMID:26619011

NCBI chr 1:55,024,328...55,066,660
Ensembl chr 1:55,024,328...55,066,640

G

solute carrier family 24 (sodium/potassium/calcium exchanger), member 3

CTD Direct Evidence: marker/mechanism

NCBI chr 2:145,009,695...145,484,086
Ensembl chr 2:145,009,674...145,484,086

G

solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2

disease_progression

RGD

NCBI chr19:8,684,931...8,700,733
Ensembl chr19:8,684,246...8,700,733

G

solute carrier family 7 (cationic amino acid transporter, y+ system), member 5

disease_progression

RGD

NCBI chr 8:122,607,885...122,634,425
Ensembl chr 8:122,607,889...122,634,433

G

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Adenoid cystic carcinoma

NCBI chr19:26,582,578...26,755,721
Ensembl chr19:26,582,450...26,755,722

G

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1

ClinVar Annotator: match by term: Adenoid cystic carcinoma

NCBI chr10:75,732,603...75,757,448
Ensembl chr10:75,732,603...75,757,451

G

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1

CTD Direct Evidence: marker/mechanism

NCBI chr11:99,099,873...99,121,843
Ensembl chr11:99,099,873...99,121,843

G

structural maintenance of chromosomes 1A

CTD Direct Evidence: marker/mechanism

NCBI chr X:150,799,386...150,844,969
Ensembl chr X:150,799,424...150,845,690

G

Son DNA binding protein

CTD Direct Evidence: marker/mechanism

NCBI chr16:91,444,712...91,476,080
Ensembl chr16:91,444,394...91,476,109

G

SRY (sex determining region Y)-box 11

CTD Direct Evidence: marker/mechanism

NCBI chr12:27,384,267...27,392,717
Ensembl chr12:27,384,263...27,392,573

G

SRY (sex determining region Y)-box 4

CTD Direct Evidence: marker/mechanism

NCBI chr13:29,132,902...29,137,682
Ensembl chr13:29,132,902...29,137,696

G

Snf2-related CREBBP activator protein

CTD Direct Evidence: marker/mechanism

NCBI chr 7:127,111,155...127,160,391
Ensembl chr 7:127,111,155...127,160,391
Ensembl chr 7:127,111,155...127,160,391

G

ST3 beta-galactoside alpha-2,3-sialyltransferase 4

CTD Direct Evidence: marker/mechanism

NCBI chr 9:34,957,872...35,028,160
Ensembl chr 9:34,957,872...35,030,564

G

signal transducer and activator of transcription 3

ClinVar Annotator: match by term: Adenoid cystic carcinoma

NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366

G

tousled-like kinase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 2:70,542,751...70,656,505
Ensembl chr 2:70,542,751...70,656,072

G

topoisomerase (DNA) II alpha

CTD Direct Evidence: marker/mechanism

NCBI chr11:98,883,773...98,915,037
Ensembl chr11:98,883,769...98,915,015

G

transformation related protein 53

disease_progression

ClinVar Annotator: match by term: Adenocystic carcinoma
CTD Direct Evidence: marker/mechanism

ClinVar
CTD
RGD

PMID:1673792 PMID:1686725 PMID:6736287 PMID:7707106 PMID:7881428 More...

NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699

G

ubiquitin-like, containing PHD and RING finger domains, 1

CTD Direct Evidence: marker/mechanism

NCBI chr17:56,610,405...56,630,486
Ensembl chr17:56,610,321...56,630,486

G

versican

CTD Direct Evidence: marker/mechanism

NCBI chr13:89,803,429...89,891,146
Ensembl chr13:89,803,431...89,890,628

G

wingless-type MMTV integration site family, member 5B

CTD Direct Evidence: marker/mechanism

NCBI chr 6:119,409,493...119,521,847
Ensembl chr 6:119,409,492...119,521,308

G

5'-3' exoribonuclease 2

DNA:hypermethylation:3' utr: (human)

RGD

NCBI chr 2:146,854,672...146,919,922
Ensembl chr 2:146,854,916...146,919,920

adenoid squamous cell carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

HNF1 homeobox A

RGD

NCBI chr 5:115,087,039...115,109,121
Ensembl chr 5:115,087,039...115,109,153

adult T-cell leukemia/lymphoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

baculoviral IAP repeat-containing 5

CTD Direct Evidence: marker/mechanism

NCBI chr11:117,740,063...117,746,569
Ensembl chr11:117,740,077...117,746,569

G

bone morphogenetic protein 6

CTD Direct Evidence: marker/mechanism

NCBI chr13:38,529,098...38,684,283
Ensembl chr13:38,529,083...38,684,278

G

caspase recruitment domain family, member 11

CTD Direct Evidence: marker/mechanism

NCBI chr 5:140,858,109...140,986,398
Ensembl chr 5:140,858,745...140,986,337

G

C-C motif chemokine receptor 4

CTD Direct Evidence: marker/mechanism

NCBI chr 9:114,319,384...114,334,544
Ensembl chr 9:114,319,384...114,333,984

G

C-C motif chemokine receptor 7

CTD Direct Evidence: marker/mechanism

NCBI chr11:99,035,025...99,045,903
Ensembl chr11:99,035,022...99,045,903

G

CD163 antigen

disease_progression

protein:increased expression:lymph node tumor (human)

RGD

NCBI chr 6:124,281,596...124,307,488
Ensembl chr 6:124,281,615...124,307,486

G

CD274 antigen

disease_progression

RGD

NCBI chr19:29,339,428...29,365,495
Ensembl chr19:29,344,855...29,365,495

G

CD28 antigen

CTD Direct Evidence: marker/mechanism

NCBI chr 1:60,785,547...60,812,521
Ensembl chr 1:60,755,959...60,812,518

G

CD68 antigen

disease_progression

protein:increased expression:lymph node tumor (human)

RGD

NCBI chr11:69,555,039...69,556,996
Ensembl chr11:69,555,039...69,556,979

G

CD80 antigen

RGD

NCBI chr16:38,277,793...38,316,682
Ensembl chr16:38,275,923...38,316,697

G

CD86 antigen

RGD

NCBI chr16:36,389,318...36,486,439
Ensembl chr16:36,424,231...36,486,443

G

casein kinase 1, alpha 1

CTD Direct Evidence: marker/mechanism

NCBI chr18:61,687,307...61,723,391
Ensembl chr18:61,688,345...61,723,132

G

casein kinase 2, alpha 1 polypeptide

CTD Direct Evidence: marker/mechanism

NCBI chr 2:152,068,468...152,123,772
Ensembl chr 2:152,068,759...152,123,772

G

casein kinase 2, beta polypeptide

CTD Direct Evidence: marker/mechanism

NCBI chr17:35,335,171...35,341,029
Ensembl chr17:35,335,172...35,341,029

G

cytotoxic T-lymphocyte-associated protein 4

CTD Direct Evidence: marker/mechanism

NCBI chr 1:60,948,184...60,954,991
Ensembl chr 1:60,926,159...60,954,991

G

Fas cell surface death receptor

susceptibility

DNA:polymorphism:promoter: -670 G>A(human)
protein:increased expression:peripheral blood mononuclear cell:

RGD

PMID:17962369 PMID:7513372

RGD:11049147, RGD:11049453

NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172

G

forkhead box P3

disease_progression

CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:23962110 PMID:23797717

NCBI chr X:7,445,915...7,461,482
Ensembl chr X:7,439,883...7,461,484

G

Fyn proto-oncogene

CTD Direct Evidence: marker/mechanism

NCBI chr10:39,245,735...39,441,377
Ensembl chr10:39,244,851...39,441,377

G

GATA binding protein 3

CTD Direct Evidence: marker/mechanism

NCBI chr 2:9,861,889...9,894,845
Ensembl chr 2:9,861,889...9,894,845

G

G protein-coupled receptor 183

CTD Direct Evidence: marker/mechanism

NCBI chr14:122,189,743...122,202,605
Ensembl chr14:122,189,963...122,202,607

G

heterogeneous nuclear ribonucleoprotein A2/B1

CTD Direct Evidence: marker/mechanism

NCBI chr 6:51,437,414...51,448,054
Ensembl chr 6:51,437,912...51,446,874

G

inducible T cell co-stimulator

CTD Direct Evidence: marker/mechanism

NCBI chr 1:60,999,909...61,039,481
Ensembl chr 1:61,017,086...61,039,479

G

interferon alpha 1

CTD Direct Evidence: therapeutic

NCBI chr 4:88,768,324...88,768,893
Ensembl chr 4:88,768,324...88,768,893

G

interferon gamma

treatment

CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:23962110 PMID:8800741

NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797

G

IKAROS family zinc finger 2

CTD Direct Evidence: marker/mechanism

NCBI chr 1:69,570,382...69,726,510
Ensembl chr 1:69,570,373...69,726,404

G

interleukin 10

CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:23962110 PMID:8704212

NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711

G

interleukin 2

CTD Direct Evidence: marker/mechanism

NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108

G

interleukin 4

CTD Direct Evidence: marker/mechanism

NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496

G

interleukin 5

disease_progression

protein:increased expression:serum

RGD

NCBI chr11:53,611,621...53,615,930
Ensembl chr11:53,611,621...53,615,933

G

interleukin 6

protein:increased expression:serum (human)

RGD

NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979

G

interferon regulatory factor 4

CTD Direct Evidence: marker/mechanism

NCBI chr13:30,933,191...30,950,965
Ensembl chr13:30,933,209...30,950,959

G

Janus kinase 3

DNA:missense mutations: :p.L156P, p.R172Q, p.E183G (human)

RGD

NCBI chr 8:72,129,027...72,143,221
Ensembl chr 8:72,128,940...72,143,219

G

myeloblastosis oncogene

disease_progression

mRNA:splice variants:CD4+ T cell:

RGD

NCBI chr10:21,000,829...21,036,883
Ensembl chr10:21,000,834...21,036,883

G

notch 1

DNA:mutations:multiple (human)

RGD

NCBI chr 2:26,347,914...26,393,834
Ensembl chr 2:26,347,915...26,406,675

G

neuroblastoma ras oncogene

disease_progression

RGD

NCBI chr 3:102,965,643...102,975,230
Ensembl chr 3:102,965,601...102,975,230

G

phospholipase C, gamma 1

CTD Direct Evidence: marker/mechanism

NCBI chr 2:160,573,230...160,617,680
Ensembl chr 2:160,573,220...160,617,680

G

protein kinase C, beta

CTD Direct Evidence: marker/mechanism

NCBI chr 7:121,888,327...122,233,625
Ensembl chr 7:121,887,974...122,233,625

G

signal transducer and activator of transcription 3

CTD Direct Evidence: marker/mechanism

NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366

G

T cell acute lymphocytic leukemia 2

NCBI chr 4:53,779,701...53,788,712
Ensembl chr 4:53,779,705...53,788,712

G

telomeric repeat binding factor 2

CTD Direct Evidence: marker/mechanism

NCBI chr 8:107,796,032...107,823,180
Ensembl chr 8:107,796,032...107,823,179

G

T cell leukemia, homeobox 1

CTD Direct Evidence: marker/mechanism

NCBI chr19:45,138,531...45,145,382
Ensembl chr19:45,139,119...45,145,382

G

tumor necrosis factor (ligand) superfamily, member 8

CTD Direct Evidence: marker/mechanism

NCBI chr 4:63,749,439...63,779,745
Ensembl chr 4:63,749,545...63,779,584

G

transformation related protein 53

GAD

NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699

G

transformation related protein 73

CTD Direct Evidence: marker/mechanism

NCBI chr 4:154,140,706...154,224,332
Ensembl chr 4:154,140,706...154,224,665

G

vav 1 oncogene

CTD Direct Evidence: marker/mechanism

NCBI chr17:57,586,080...57,636,236
Ensembl chr17:57,586,100...57,635,031

anaplastic large cell lymphoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

anaplastic lymphoma kinase

CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:16151469 PMID:19503098 PMID:21345110 PMID:22155737 PMID:22920921 More...

NCBI chr17:72,174,206...72,911,719
Ensembl chr17:72,175,967...72,911,622

G

heat shock protein 90, alpha (cytosolic), class A member 1

CTD Direct Evidence: marker/mechanism

NCBI chr12:110,657,470...110,662,829
Ensembl chr12:110,657,039...110,669,162

G

interferon regulatory factor 4

DNA:translocation

RGD

NCBI chr13:30,933,191...30,950,965
Ensembl chr13:30,933,209...30,950,959

G

jun B proto-oncogene

RGD

NCBI chr 8:85,703,538...85,705,377
Ensembl chr 8:85,701,113...85,705,347

G

nucleophosmin 1

RGD

NCBI chr11:33,102,498...33,114,143
Ensembl chr11:33,102,287...33,113,206

G

v-rel reticuloendotheliosis viral oncogene homolog A (avian)

CTD Direct Evidence: marker/mechanism

NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158

G

signal transducer and activator of transcription 3

CTD Direct Evidence: marker/mechanism

NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366

G

tumor necrosis factor receptor superfamily, member 8

CTD Direct Evidence: marker/mechanism

PMID:10908157 PMID:17261581

NCBI chr 4:144,993,702...145,041,734
Ensembl chr 4:144,993,707...145,041,734

G

twist basic helix-loop-helix transcription factor 1

CTD Direct Evidence: marker/mechanism

NCBI chr12:34,007,670...34,009,830
Ensembl chr12:34,007,670...34,009,828

angioimmunoblastic T-cell lymphoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

tet methylcytosine dioxygenase 2

ClinVar Annotator: match by term: Angioimmunoblastic T-cell lymphoma

PMID:19797729 PMID:27210295 PMID:27276561 PMID:28337768 PMID:28492532 More...

NCBI chr 3:133,169,438...133,250,882
Ensembl chr 3:133,169,440...133,250,900

B-cell acute lymphoblastic leukemia

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

excision repair cross-complementing rodent repair deficiency, complementation group 4

ClinVar Annotator: match by term: Precursor B-cell acute lymphoblastic leukemia

PMID:23623386 PMID:25741868

NCBI chr16:12,927,600...12,969,873
Ensembl chr16:12,927,548...12,968,481

G

Wt1 promoter region

ClinVar Annotator: match by term: B Acute Lymphoblastic Leukemia

PMID:8621495 PMID:12640141 PMID:16987884 PMID:25741868 PMID:28492532 More...

NCBI chr 2:104,956,361...104,957,127

G

neurofibromin 1

ClinVar Annotator: match by term: Precursor B-cell acute lymphoblastic leukemia

PMID:9536098 PMID:17576681 PMID:23656349 PMID:25741868 PMID:28492532

NCBI chr11:79,223,541...79,472,435
Ensembl chr11:79,230,519...79,472,438

G

WT1 transcription factor

ClinVar Annotator: match by term: B Acute Lymphoblastic Leukemia

PMID:8621495 PMID:12640141 PMID:16987884 PMID:25741868 PMID:28492532 More...

NCBI chr 2:104,956,874...105,003,959
Ensembl chr 2:104,956,874...105,003,961

B-Cell Chronic Lymphocytic Leukemia

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily G member 2 (Junior blood group)

susceptibility

DNA:SNPs,haplotype: :rs1481012,rs2231142(human)

RGD

NCBI chr 6:58,561,476...58,669,436
Ensembl chr 6:58,561,508...58,672,661

G

acyl-Coenzyme A oxidase-like

CTD Direct Evidence: marker/mechanism

NCBI chr 2:127,680,717...127,968,172
Ensembl chr 2:127,680,796...127,965,793

G

activation-induced cytidine deaminase

disease_progression

RGD

NCBI chr 6:122,530,768...122,541,139
Ensembl chr 6:122,530,760...122,541,139

G

apolipoprotein E

disease_progression

RGD

NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113

G

ataxia telangiectasia mutated

CTD Direct Evidence: marker/mechanism

NCBI chr 9:53,348,422...53,448,125
Ensembl chr 9:53,350,449...53,448,040

G

BCL11 transcription factor A

DNA:translocation:5' utr: (human)

RGD

NCBI chr11:24,026,498...24,123,558
Ensembl chr11:24,028,056...24,124,123

G

B cell leukemia/lymphoma 2

treatment
severity
no_association

CTD Direct Evidence: marker/mechanism
protein:increased expression:B cell (human)
DNA:snp:promoter:g.-938C>A (human)

CTD
RGD

PMID:21750559 PMID:23770605 PMID:17296974 PMID:20001236 PMID:17959858 More...

RGD:11522735, RGD:11526110, RGD:11526105, RGD:11526104

NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004

G

BCL2 modifying factor

CTD Direct Evidence: marker/mechanism

NCBI chr 2:118,359,238...118,385,240
Ensembl chr 2:118,359,238...118,380,168

G

Braf transforming gene

ClinVar Annotator: match by term: B-cell chronic lymphocytic leukemia | ClinVar Annotator: match by term: Leukemia, B-cell, chronic

PMID:12068308 PMID:12198537 PMID:12692057 PMID:12960123 PMID:14612909 More...

NCBI chr 6:39,580,171...39,702,592
Ensembl chr 6:39,580,171...39,702,397

G

Bruton agammaglobulinemia tyrosine kinase

treatment

ClinVar Annotator: match by term: B-cell chronic lymphocytic leukemia

PMID:24869598 PMID:25741868 PMID:28492532 PMID:23045577

NCBI chr X:133,443,083...133,484,366
Ensembl chr X:133,443,085...133,484,319

G

Casitas B-lineage lymphoma

severity

mRNA,protein:increased expression:CD5+ B cell:
DNA:hypophosphorylation:CD5+ B cell:

RGD

PMID:17804547 PMID:17804547

RGD:11038803, RGD:11038803

NCBI chr 9:44,054,273...44,145,556
Ensembl chr 9:44,054,273...44,145,346

G

coiled-coil domain containing 50

RGD

NCBI chr16:27,205,815...27,270,968
Ensembl chr16:27,207,619...27,270,968

G

CD40 antigen

RGD

NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868

G

CD40 ligand

mouse-human chimeric gene in human

RGD

NCBI chr X:56,257,448...56,269,402
Ensembl chr X:56,257,503...56,269,402

G

CD5 antigen

CTD Direct Evidence: marker/mechanism

NCBI chr19:10,695,471...10,716,390
Ensembl chr19:10,694,480...10,716,366

G

CD79B antigen

protein:decreased expression:B lymphocyte, cell surface (human)
DNA:polymorphism:multiple (human)
mRNA, protein:splice variants, alternative forms:exon 3 (human)

RGD

PMID:9269755 PMID:10552962 PMID:10090943

RGD:11250403, RGD:151665202, RGD:151665190

NCBI chr11:106,202,167...106,205,388
Ensembl chr11:106,202,167...106,205,588

G

CD86 antigen

severity

protein:increased expression:peripheral blood mononuclear cell (human)

RGD

NCBI chr16:36,389,318...36,486,439
Ensembl chr16:36,424,231...36,486,443

G

cytoplasmic polyadenylation element binding protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr 7:80,996,774...81,105,207
Ensembl chr 7:80,996,774...81,105,213

G

cytotoxic T-lymphocyte-associated protein 4

protein:increased expression:T cell

RGD

PMID:16094420 PMID:15914560

RGD:11344923, RGD:11352246

NCBI chr 1:60,948,184...60,954,991
Ensembl chr 1:60,926,159...60,954,991

G

dyskeratosis congenita 1, dyskerin

RGD

NCBI chr X:74,139,460...74,153,382
Ensembl chr X:74,139,460...74,153,383

G

DNA methyltransferase 3B

mRNA:decreased expression: B cell

RGD

NCBI chr 2:153,491,332...153,529,650
Ensembl chr 2:153,491,370...153,529,650

G

excision repair cross-complementing rodent repair deficiency, complementation group 2

severity

DNA:SNP: :p.K751Q (rs13181) (human)

RGD

PMID:22739018 PMID:19484764

RGD:11252203, RGD:11252204

NCBI chr 7:19,115,942...19,129,619
Ensembl chr 7:19,115,935...19,129,619

G

FERM, RhoGEF and pleckstrin domain protein 2

CTD Direct Evidence: marker/mechanism

NCBI chr 1:93,439,826...93,549,698
Ensembl chr 1:93,439,801...93,549,698

G

Fas cell surface death receptor

disease_progression

RGD

NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172

G

F-box and WD-40 domain protein 7

ClinVar Annotator: match by term: Leukemia, B-cell, chronic

PMID:25741868 PMID:26619011

NCBI chr 3:84,721,901...84,886,505
Ensembl chr 3:84,722,575...84,886,505

G

Fc receptor, IgG, low affinity IV

no_association

DNA:SNP:exon:p.F158V (rs396991) (human)

RGD

NCBI chr 1:170,846,495...170,857,330
Ensembl chr 1:170,846,489...170,857,330

G

GNAS complex locus

disease_progression

DNA:polymorphism:393T>C (human)

RGD

NCBI chr 2:174,126,113...174,188,537
Ensembl chr 2:174,126,113...174,188,537

G

Harvey rat sarcoma virus oncogene

ClinVar Annotator: match by term: Leukemia, B-cell, chronic

PMID:12835555 PMID:16329078 PMID:16372351 PMID:16835863 PMID:17211612 More...

NCBI chr 7:140,770,839...140,773,938
Ensembl chr 7:140,769,018...140,773,918

G

intercellular adhesion molecule 1

severity

RGD

NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113

G

interferon gamma

susceptibility

DNA:polymorphism: :847A>T(human)

RGD

NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797

G

interleukin 10

disease_progression
no_association

protein:increased expression:serum
DNA:SNPs: :multiple
DNA:SNPs: :rs1800890, rs4072227, rs17015865 (human)

RGD

PMID:22945689 PMID:10638947 PMID:19573080 PMID:19573080

RGD:11041895, RGD:11049174, RGD:11049165, RGD:11049165

NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711

G

interleukin 19

CTD Direct Evidence: marker/mechanism

NCBI chr 1:130,860,393...130,873,194
Ensembl chr 1:130,860,393...130,867,852

G

interleukin 1 alpha

RGD

NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892

G

interleukin 1 beta

severity

DNA:SNP:promoter:-511C>T (human)
protein:decreased expression:plasma:

RGD

PMID:18271063 PMID:10870116

RGD:11051967, RGD:11522755

NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059

G

interleukin 1 receptor antagonist

protein:decreased expression:plasma:

RGD

NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506

G

interleukin 6

protein:increased expression:plasma:
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:18006695 PMID:10870116

NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979

G

interferon regulatory factor 4

disease_progression

CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:18758461 PMID:12393648 PMID:12079517

RGD:11526160, RGD:11530024

NCBI chr13:30,933,191...30,950,965
Ensembl chr13:30,933,209...30,950,959

G

integrin alpha 4

CTD Direct Evidence: marker/mechanism

NCBI chr 2:79,084,767...79,163,458
Ensembl chr 2:79,085,770...79,163,467

G

Kirsten rat sarcoma viral oncogene homolog

ClinVar Annotator: match by term: Leukemia, B-cell, chronic

PMID:2278970 PMID:3122217 PMID:12460918 PMID:15696205 PMID:16361624 More...

NCBI chr 6:145,162,425...145,197,631
Ensembl chr 6:145,162,425...145,195,965

G

lymphoid enhancer binding factor 1

CTD Direct Evidence: marker/mechanism

NCBI chr 3:130,903,972...131,018,006
Ensembl chr 3:130,904,120...131,018,005

G

leucine rich repeat containing 56

ClinVar Annotator: match by term: Leukemia, B-cell, chronic

PMID:12835555 PMID:16329078 PMID:16372351 PMID:16835863 PMID:17211612 More...

NCBI chr 7:140,774,024...140,789,968
Ensembl chr 7:140,774,070...140,789,968

G

microRNA 143

CTD Direct Evidence: marker/mechanism

NCBI chr18:61,782,267...61,782,329
Ensembl chr18:61,782,267...61,782,329

G

microRNA 145a

CTD Direct Evidence: marker/mechanism

NCBI chr18:61,780,896...61,780,965
Ensembl chr18:61,780,896...61,780,965

G

membrane-spanning 4-domains, subfamily A, member 1

RGD

NCBI chr19:11,227,043...11,243,513
Ensembl chr19:11,227,039...11,243,605

G

methylenetetrahydrofolate reductase

CTD Direct Evidence: marker/mechanism

NCBI chr 4:148,123,534...148,144,019
Ensembl chr 4:148,123,534...148,144,008

G

myeloid differentiation primary response gene 88

ClinVar Annotator: match by term: Leukemia, B-cell, chronic

PMID:21179087 PMID:22931316 PMID:23215570 PMID:23355535 PMID:26619011 More...

NCBI chr 9:119,165,000...119,169,084
Ensembl chr 9:119,165,000...119,170,477

G

neuroblastoma ras oncogene

ClinVar Annotator: match by term: Leukemia, B-cell, chronic

PMID:1654209 PMID:2278970 PMID:2674680 PMID:3122217 PMID:6587382 More...

NCBI chr 3:102,965,643...102,975,230
Ensembl chr 3:102,965,601...102,975,230

G

purinergic receptor P2X, ligand-gated ion channel, 7

CTD Direct Evidence: marker/mechanism

NCBI chr 5:122,781,990...122,830,399
Ensembl chr 5:122,781,974...122,829,495

G

platelet/endothelial cell adhesion molecule 1

severity

protein:increased expression:B cell (human)

RGD

NCBI chr11:106,545,039...106,606,107
Ensembl chr11:106,545,043...106,641,454

G

phospholipase C, gamma 2

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: B-cell chronic lymphocytic leukemia

PMID:24869598 PMID:27542411 PMID:28492532

NCBI chr 8:118,225,014...118,361,881
Ensembl chr 8:118,225,030...118,361,881

G

phorbol-12-myristate-13-acetate-induced protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr18:66,591,675...66,598,629
Ensembl chr18:66,591,604...66,598,636

G

polymerase (DNA directed), beta

CTD Direct Evidence: marker/mechanism

NCBI chr 8:23,118,135...23,143,482
Ensembl chr 8:23,118,142...23,143,451

G

protein phosphatase 2, regulatory subunit B', gamma

CTD Direct Evidence: marker/mechanism

NCBI chr12:110,413,532...110,549,509
Ensembl chr12:110,413,554...110,549,496

G

PRAME like, X-linked 1

protein:increased expression:mononuclear cell (human)

RGD

NCBI chr X:134,513,662...134,528,437
Ensembl chr X:134,513,751...134,528,454

G

protein kinase D2

CTD Direct Evidence: marker/mechanism

NCBI chr 7:16,576,827...16,604,386
Ensembl chr 7:16,576,827...16,604,389

G

prostaglandin-endoperoxide synthase 2

CTD Direct Evidence: marker/mechanism

NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978

G

protein tyrosine phosphatase, non-receptor type 11

ClinVar Annotator: match by term: B-cell chronic lymphocytic leukemia | ClinVar Annotator: match by term: Leukemia, B-cell, chronic

PMID:12161469 PMID:12717436 PMID:14644997 PMID:14982869 PMID:15385933 More...

NCBI chr 5:121,268,596...121,329,460
Ensembl chr 5:121,268,596...121,329,460

G

glutaminyl-peptide cyclotransferase (glutaminyl cyclase)

CTD Direct Evidence: marker/mechanism

NCBI chr17:79,359,335...79,397,807
Ensembl chr17:79,359,335...79,397,807

G

RB transcriptional corepressor like 2

CTD Direct Evidence: marker/mechanism

NCBI chr 8:91,796,685...91,850,472
Ensembl chr 8:91,796,685...91,850,472

G

splicing factor 3b, subunit 1

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: B-cell chronic lymphocytic leukemia | ClinVar Annotator: match by term: Leukemia, B-cell, chronic

PMID:22158541 PMID:23634996 PMID:25741868 PMID:26619011

NCBI chr 1:55,024,328...55,066,660
Ensembl chr 1:55,024,328...55,066,640

G

splicing factor 3b, subunit 2

ClinVar Annotator: match by term: B-cell chronic lymphocytic leukemia | ClinVar Annotator: match by term: Leukemia, B-cell, chronic

NCBI chr19:5,323,949...5,345,485
Ensembl chr19:5,323,960...5,345,483

G

telomerase reverse transcriptase

disease_progression

RGD

NCBI chr13:73,775,030...73,797,962
Ensembl chr13:73,775,030...73,797,962

G

transferrin receptor

CTD Direct Evidence: marker/mechanism

NCBI chr16:32,427,714...32,451,612
Ensembl chr16:32,427,738...32,451,612

G

thrombomodulin

RGD

NCBI chr 2:148,246,391...148,250,108
Ensembl chr 2:148,246,386...148,250,108

G

tumor necrosis factor

disease_progression

protein:increased expression:bone marrow, blood, lymphocyte

RGD

PMID:12010662 PMID:22945689

RGD:10449463, RGD:11041895

NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983

G

tumor necrosis factor receptor superfamily, member 10b

susceptibility

DNA:missense mutation:cds:p.E228A (c.683A>C) (human)
DNA:SNP: :1322A>G (human)

RGD

PMID:16217763 PMID:15531454

RGD:11038717, RGD:11038718

NCBI chr14:70,004,921...70,021,860
Ensembl chr14:70,004,921...70,021,860

G

tumor necrosis factor receptor superfamily, member 11a, NFKB activator

CTD Direct Evidence: marker/mechanism

NCBI chr 1:105,708,443...105,777,172
Ensembl chr 1:105,708,443...105,775,709

G

tumor necrosis factor (ligand) superfamily, member 11

CTD Direct Evidence: marker/mechanism

NCBI chr14:78,514,886...78,545,483
Ensembl chr14:78,514,885...78,545,483

G

tumor necrosis factor (ligand) superfamily, member 13

protein:increased expression:serum

RGD

NCBI chr11:69,573,403...69,576,380
Ensembl chr11:69,573,672...69,576,610

G

tumor necrosis factor (ligand) superfamily, member 8

CTD Direct Evidence: marker/mechanism

NCBI chr 4:63,749,439...63,779,745
Ensembl chr 4:63,749,545...63,779,584

G

topoisomerase (DNA) II binding protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr 9:103,182,351...103,227,627
Ensembl chr 9:103,182,414...103,227,627

G

transformation related protein 53

disease_progression

DNA:deletion: :
ClinVar Annotator: match by term: B-cell chronic lymphocytic leukemia | ClinVar Annotator: match by term: Leukemia, B-cell, chronic
CTD Direct Evidence: marker/mechanism

ClinVar
CTD
RGD

PMID:253702 PMID:1565143 PMID:1565144 PMID:1631137 PMID:1679237 More...

NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699

G

vitamin D (1,25-dihydroxyvitamin D3) receptor

CTD Direct Evidence: marker/mechanism

NCBI chr15:97,752,308...97,806,177
Ensembl chr15:97,752,306...97,808,511

G

exportin 1

ClinVar Annotator: match by term: Leukemia, B-cell, chronic

NCBI chr11:23,205,768...23,248,250
Ensembl chr11:23,206,055...23,248,249

G

X-ray repair complementing defective repair in Chinese hamster cells 1

severity
no_association

DNA:SNP: :p.R399Q (rs25487) (human)
DNA:SNP: :p.R194W (rs1799782), p.R280H (25489) (human)

RGD

PMID:19484764 PMID:19484764

RGD:11252204, RGD:11252204

NCBI chr 7:24,246,124...24,272,863
Ensembl chr 7:24,245,714...24,272,865

B-cell lymphoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily G member 2 (Junior blood group)

susceptibility

DNA:SNP: :rs6857600(human)

RGD

NCBI chr 6:58,561,476...58,669,436
Ensembl chr 6:58,561,508...58,672,661

G

activation-induced cytidine deaminase

RGD

NCBI chr 6:122,530,768...122,541,139
Ensembl chr 6:122,530,760...122,541,139

G

BCL2-like 2

disease_progression

RGD

NCBI chr14:55,120,900...55,125,691
Ensembl chr14:55,120,834...55,125,691

G

B cell leukemia/lymphoma 6

diffuse large B-cell lymphoma

RGD

NCBI chr16:23,780,058...23,807,602
Ensembl chr16:23,783,802...23,807,602

G

bromodomain containing 2

RGD

NCBI chr17:34,330,993...34,341,581
Ensembl chr17:34,330,997...34,341,608

G

Bruton agammaglobulinemia tyrosine kinase

treatment

human cell in a mouse model

RGD

PMID:25662332 PMID:28348046

RGD:11040764, RGD:124713554

NCBI chr X:133,443,083...133,484,366
Ensembl chr X:133,443,085...133,484,319

G

chromobox 7

RGD

NCBI chr15:79,800,005...79,855,344
Ensembl chr15:79,800,008...79,855,320

G

CD40 antigen

RGD

NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868

G

colony stimulating factor 2 (granulocyte-macrophage)

treatment

RGD

NCBI chr11:54,138,096...54,140,725
Ensembl chr11:54,138,097...54,140,493

G

colony stimulating factor 3 (granulocyte)

CTD Direct Evidence: therapeutic

NCBI chr11:98,591,287...98,594,457
Ensembl chr11:98,592,089...98,594,455

G

ELL associated factor 2

CTD Direct Evidence: marker/mechanism

NCBI chr16:36,613,246...36,695,275
Ensembl chr16:36,613,246...36,695,365

G

enhancer of zeste 2 polycomb repressive complex 2 subunit

severity
treatment

PMID:23982173 PMID:29456795

RGD:10755356, RGD:126781726

NCBI chr 6:47,507,208...47,613,843
Ensembl chr 6:47,507,073...47,572,275

G

interleukin 21 receptor

diffuse large B-cell lymphoma

RGD

NCBI chr 7:125,202,424...125,232,742
Ensembl chr 7:125,202,601...125,232,742

G

Janus kinase 3

CTD Direct Evidence: marker/mechanism

NCBI chr 8:72,129,027...72,143,221
Ensembl chr 8:72,128,940...72,143,219

G

K(lysine) acetyltransferase 5

severity

RGD

NCBI chr19:5,653,042...5,661,584
Ensembl chr19:5,653,042...5,660,265

G

lectin, galactose binding, soluble 1

protein:increased expression:primary tumor (rat)

RGD

NCBI chr15:78,810,925...78,814,665
Ensembl chr15:78,810,925...78,814,665

G

microRNA 143

CTD Direct Evidence: marker/mechanism

NCBI chr18:61,782,267...61,782,329
Ensembl chr18:61,782,267...61,782,329

G

microRNA 145a

CTD Direct Evidence: marker/mechanism

NCBI chr18:61,780,896...61,780,965
Ensembl chr18:61,780,896...61,780,965

G

neuroblastoma ras oncogene

CTD Direct Evidence: marker/mechanism

NCBI chr 3:102,965,643...102,975,230
Ensembl chr 3:102,965,601...102,975,230

G

prostaglandin-endoperoxide synthase 2

CTD Direct Evidence: marker/mechanism

NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978

G

protein tyrosine phosphatase, non-receptor type 1

CTD Direct Evidence: marker/mechanism

NCBI chr 2:167,772,670...167,821,305
Ensembl chr 2:167,773,977...167,821,305

G

signal transducer and activator of transcription 5A

RGD

NCBI chr11:100,750,177...100,775,995
Ensembl chr11:100,750,177...100,775,995

G

tumor necrosis factor (ligand) superfamily, member 8

CTD Direct Evidence: marker/mechanism

NCBI chr 4:63,749,439...63,779,745
Ensembl chr 4:63,749,545...63,779,584

G

tumor necrosis factor (ligand) superfamily, member 9

RGD

NCBI chr17:57,412,113...57,414,757
Ensembl chr17:57,412,325...57,414,757

B-lymphoblastic leukemia/lymphoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

c-abl oncogene 1, non-receptor tyrosine kinase

treatment

RGD

NCBI chr 2:31,578,256...31,697,105
Ensembl chr 2:31,578,388...31,694,239

G

aryl-hydrocarbon receptor

CTD Direct Evidence: marker/mechanism

NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037

G

aldo-keto reductase family 1, member C18

treatment

RGD

NCBI chr13:4,182,614...4,200,645
Ensembl chr13:4,182,614...4,200,653

G

activating transcription factor 7 interacting protein

CTD Direct Evidence: marker/mechanism

NCBI chr 6:136,495,787...136,587,848
Ensembl chr 6:136,483,165...136,587,860

G

BCL2-like 1

severity

RGD

NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648

G

BCR activator of RhoGEF and GTPase

BCR/ABL fusion

RGD

NCBI chr10:74,896,384...75,020,753
Ensembl chr10:74,896,424...75,020,753

G

bromodomain containing 2

RGD

NCBI chr17:34,330,993...34,341,581
Ensembl chr17:34,330,997...34,341,608

G

cellular communication network factor 2

CTD Direct Evidence: marker/mechanism

NCBI chr10:24,471,340...24,474,581
Ensembl chr10:24,471,340...24,474,581

G

cyclin D1

mRNA:increased expression:B cell (mouse)

RGD

NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662

G

cyclin dependent kinase inhibitor 2A

treatment
susceptibility

DNA:mutation:cds:c.442C>T,p.A148T,rs3731249 (human)

RGD

PMID:16618932 PMID:26104880 PMID:21622646

RGD:11251751, RGD:11057958, RGD:11251772

NCBI chr 4:89,192,710...89,212,856
Ensembl chr 4:89,192,708...89,212,890

G

cytokine receptor-like factor 2

CTD Direct Evidence: marker/mechanism

NCBI chr 5:109,702,575...109,707,301
Ensembl chr 5:109,702,575...109,706,859

G

cytochrome P450, family 3, subfamily a, polypeptide 13

treatment

DNA:polymorphisms: :

RGD

NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881

G

double homeobox B-like 1

CTD Direct Evidence: marker/mechanism

NCBI chr14:25,979,011...25,990,590
Ensembl chr14:25,979,001...25,990,512

G

ets variant 6

CTD Direct Evidence: marker/mechanism

PMID:15217836 PMID:24413735 PMID:25807284

NCBI chr 6:134,012,663...134,247,121
Ensembl chr 6:134,012,663...134,247,121

G

coagulation factor XIII, A1 subunit

protein:increased expression:B lymphoblast:

RGD

NCBI chr13:37,051,150...37,234,220
Ensembl chr13:37,051,152...37,234,220

G

coagulation factor III

treatment

RGD

NCBI chr 3:121,517,186...121,528,701
Ensembl chr 3:121,517,186...121,528,697

G

fumarate hydratase 1

ClinVar Annotator: match by term: B Lymphoblastic Leukemia/Lymphoma, Not Otherwise Specified

PMID:25741868 PMID:28492532

NCBI chr 1:175,428,944...175,453,201
Ensembl chr 1:175,427,940...175,453,201

G

FMS-like tyrosine kinase 3

mRNA,protein:increased expression:bone marrow:

RGD

NCBI chr 5:147,267,551...147,337,299
Ensembl chr 5:147,267,551...147,337,299

G

GATA binding protein 3

CTD Direct Evidence: marker/mechanism

NCBI chr 2:9,861,889...9,894,845
Ensembl chr 2:9,861,889...9,894,845

G

indoleamine 2,3-dioxygenase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 8:25,074,148...25,086,987
Ensembl chr 8:25,074,152...25,087,025

G

IKAROS family zinc finger 1

disease_progression

DNA:mutations: :
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:24141364 PMID:22699455

NCBI chr11:11,634,970...11,722,930
Ensembl chr11:11,634,980...11,722,926

G

interleukin 5

RGD

NCBI chr11:53,611,621...53,615,930
Ensembl chr11:53,611,621...53,615,933

G

interferon regulatory factor 4

RGD

PMID:25006123 PMID:20585039 PMID:21818355

RGD:11526159, RGD:11530030, RGD:11530020

NCBI chr13:30,933,191...30,950,965
Ensembl chr13:30,933,209...30,950,959

G

interferon regulatory factor 8

RGD

NCBI chr 8:121,463,097...121,483,433
Ensembl chr 8:121,463,097...121,483,433

G

intestine specific homeobox

CTD Direct Evidence: marker/mechanism

NCBI chr 8:75,599,326...75,620,134
Ensembl chr 8:75,599,801...75,620,134

G

Wt1 promoter region

ClinVar Annotator: match by term: Pre-B-cell acute lymphoblastic leukemia

PMID:8621495 PMID:12640141 PMID:16987884 PMID:25741868 PMID:28492532 More...

NCBI chr 2:104,956,361...104,957,127

G

MAX gene associated

CTD Direct Evidence: marker/mechanism

NCBI chr 2:119,702,974...119,800,610
Ensembl chr 2:119,727,709...119,800,062

G

myeloblastosis oncogene

disease_progression

mRNA:splice variants:cds:

RGD

NCBI chr10:21,000,829...21,036,883
Ensembl chr10:21,000,834...21,036,883

G

myelocytomatosis oncogene

RGD

NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223

G

paired box 5

CTD Direct Evidence: marker/mechanism

PMID:24013638 PMID:30643249

NCBI chr 4:44,524,748...44,710,694
Ensembl chr 4:44,524,757...44,710,487

G

platelet derived growth factor receptor, alpha polypeptide

treatment

RGD

NCBI chr 5:75,311,988...75,358,867
Ensembl chr 5:75,312,953...75,358,876

G

RB transcriptional corepressor 1

ClinVar Annotator: match by term: B Lymphoblastic Leukemia/Lymphoma, Not Otherwise Specified

PMID:25741868 PMID:28492532

NCBI chr14:73,430,298...73,563,446
Ensembl chr14:73,421,113...73,563,262

G

runt related transcription factor 1

onset

DNA:amplification
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:15217836 PMID:24413735 PMID:21822204

NCBI chr16:92,398,354...92,622,962
Ensembl chr16:92,398,354...92,623,037

G

signal transducer and activator of transcription 3

CTD Direct Evidence: marker/mechanism

NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366

G

signal transducer and activator of transcription 5A

protein:increased phosphorylation:bone marrow (human)

RGD

NCBI chr11:100,750,177...100,775,995
Ensembl chr11:100,750,177...100,775,995

G

serine/threonine kinase 11

ClinVar Annotator: match by term: B Lymphoblastic Leukemia/Lymphoma, Not Otherwise Specified

PMID:25741868 PMID:26080840 PMID:26295973 PMID:28492532

NCBI chr10:79,951,602...79,966,513
Ensembl chr10:79,951,637...79,966,516

G

SUFU negative regulator of hedgehog signaling

ClinVar Annotator: match by term: B Lymphoblastic Leukemia/Lymphoma, Not Otherwise Specified

PMID:25741868 PMID:28492532

NCBI chr19:46,385,335...46,477,243
Ensembl chr19:46,385,335...46,477,243

G

transcription factor 3

CTD Direct Evidence: marker/mechanism

NCBI chr10:80,245,375...80,269,814
Ensembl chr10:80,245,348...80,269,481

G

tryptophan 2,3-dioxygenase

CTD Direct Evidence: marker/mechanism

NCBI chr 3:81,865,719...81,883,035
Ensembl chr 3:81,864,397...81,883,509

G

tissue factor pathway inhibitor

treatment

RGD

NCBI chr 2:84,263,199...84,307,119
Ensembl chr 2:84,263,199...84,307,119

G

tumor necrosis factor (ligand) superfamily, member 13

RGD

NCBI chr11:69,573,403...69,576,380
Ensembl chr11:69,573,672...69,576,610

G

tumor necrosis factor (ligand) superfamily, member 8

CTD Direct Evidence: marker/mechanism

NCBI chr 4:63,749,439...63,779,745
Ensembl chr 4:63,749,545...63,779,584

G

transformation related protein 53

disease_progression

DNA:mutations: :

RGD

NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699

G

WT1 transcription factor

ClinVar Annotator: match by term: Pre-B-cell acute lymphoblastic leukemia

PMID:8621495 PMID:12640141 PMID:16987884 PMID:25741868 PMID:28492532 More...

NCBI chr 2:104,956,874...105,003,959
Ensembl chr 2:104,956,874...105,003,961

B-lymphoblastic leukemia/lymphoma MLL rearranged

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

WT1 transcription factor

ClinVar Annotator: match by term: Mixed phenotype acute leukemia with t(v;11q23.3)

NCBI chr 2:104,956,874...105,003,959
Ensembl chr 2:104,956,874...105,003,961

B-lymphoblastic leukemia/lymphoma with BCR-ABL1

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

mutS homolog 6

ClinVar Annotator: match by term: B Lymphoblastic Leukemia/Lymphoma with t(9;22)(q34.1;q11.2); BCR-ABL1

PMID:22658618 PMID:25741868 PMID:28492532

NCBI chr17:88,282,478...88,298,320
Ensembl chr17:88,282,490...88,298,320

B-lymphoblastic leukemia/lymphoma with ETV6-RUNX1

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

bone morphogenetic protein receptor, type 1A

ClinVar Annotator: match by term: B Lymphoblastic Leukemia/Lymphoma with t(12;21)(p13.2;q22.1); ETV6-RUNX1

PMID:25741868 PMID:28492532 PMID:30093976

NCBI chr14:34,133,018...34,225,335
Ensembl chr14:34,132,691...34,225,298

G

partner and localizer of BRCA2

ClinVar Annotator: match by term: B Lymphoblastic Leukemia/Lymphoma with t(12;21)(p13.2;q22.1); ETV6-RUNX1

PMID:25741868 PMID:28492532 PMID:33471991

NCBI chr 7:121,706,485...121,732,203
Ensembl chr 7:121,706,485...121,732,208

G

RB transcriptional corepressor 1

ClinVar Annotator: match by term: B Lymphoblastic Leukemia/Lymphoma with t(12;21)(p13.2;q22.1); ETV6-RUNX1

PMID:25741868 PMID:28492532

NCBI chr14:73,430,298...73,563,446
Ensembl chr14:73,421,113...73,563,262

G

RecQ protein-like 4

ClinVar Annotator: match by term: B Lymphoblastic Leukemia/Lymphoma with t(12;21)(p13.2;q22.1); ETV6-RUNX1

PMID:10678659 PMID:12734318 PMID:12838562 PMID:12952869 PMID:15897384 More...

NCBI chr15:76,587,753...76,594,820
Ensembl chr15:76,587,753...76,594,748

B-lymphoblastic leukemia/lymphoma with hyperdiploidy

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

Casitas B-lineage lymphoma

ClinVar Annotator: match by term: B lymphoblastic leukemia lymphoma with hyperdiploidy

PMID:24033266 PMID:25741868 PMID:28492532

NCBI chr 9:44,054,273...44,145,556
Ensembl chr 9:44,054,273...44,145,346

B-lymphoblastic leukemia/lymphoma with hypodiploidy

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

succinate dehydrogenase complex, subunit A, flavoprotein (Fp)

ClinVar Annotator: match by term: B-lymphoblastic leukemia/lymphoma with hypodiploidy

PMID:25741868 PMID:28492532

NCBI chr13:74,470,374...74,498,359
Ensembl chr13:74,470,373...74,498,399

Burkitt lymphoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

alpha 1,4-galactosyltransferase

CTD Direct Evidence: marker/mechanism

NCBI chr15:83,110,923...83,135,930
Ensembl chr15:83,110,923...83,135,975

G

AT-rich interaction domain 1A

CTD Direct Evidence: marker/mechanism

NCBI chr 4:133,406,319...133,484,682
Ensembl chr 4:133,406,319...133,484,080

G

BCL2 binding component 3

CTD Direct Evidence: marker/mechanism

NCBI chr 7:16,042,307...16,052,130
Ensembl chr 7:16,042,318...16,052,130

G

BCL2-like 2

mRNA:increased expression:lymph node

RGD

NCBI chr14:55,120,900...55,125,691
Ensembl chr14:55,120,834...55,125,691

G

breast cancer 1, early onset

ClinVar Annotator: match by term: Burkitt lymphoma

PMID:17262179 PMID:25741868 PMID:26467025 PMID:28492532 PMID:31911673 More...

NCBI chr11:101,379,587...101,442,808
Ensembl chr11:101,379,590...101,442,781

G

Bruton agammaglobulinemia tyrosine kinase

ameliorates
treatment

Human cell line in a mouse model
mRNA:increased expression:multiple (human)

PMID:28474336 PMID:30546948

RGD:124713565, RGD:124715474

NCBI chr X:133,443,083...133,484,366
Ensembl chr X:133,443,085...133,484,319

G

calreticulin

treatment

human cells and recombinant protein in a mouse model
human cell line and recombinant protein in a mouse model

RGD

PMID:9858521 PMID:10961892

RGD:150521687, RGD:150521702

NCBI chr 8:85,568,717...85,573,560
Ensembl chr 8:85,568,479...85,573,563

G

chaperonin containing TCP1 subunit 6B

CTD Direct Evidence: marker/mechanism

NCBI chr11:82,603,938...82,655,154
Ensembl chr11:82,610,076...82,655,147

G

CD40 antigen

treatment

human cell line in a mouse model

RGD

NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868

G

CD79B antigen

treatment

human cells in mouse model

RGD

NCBI chr11:106,202,167...106,205,388
Ensembl chr11:106,202,167...106,205,588

G

formiminotransferase cyclodeaminase

CTD Direct Evidence: marker/mechanism

NCBI chr10:76,411,482...76,426,172
Ensembl chr10:76,411,482...76,426,172

G

guanine nucleotide binding protein, alpha 13

CTD Direct Evidence: marker/mechanism

NCBI chr11:109,253,620...109,292,195
Ensembl chr11:109,253,657...109,292,195

G

inhibitor of DNA binding 3

CTD Direct Evidence: marker/mechanism

PMID:23143595 PMID:23143597

NCBI chr 4:135,871,133...135,872,703
Ensembl chr 4:135,870,808...135,873,066

G

microRNA 21a

treatment

RGD

NCBI chr11:86,474,893...86,474,984
Ensembl chr11:86,474,893...86,474,984

G

microRNA 23b

treatment

RGD

NCBI chr13:63,448,298...63,448,371
Ensembl chr13:63,448,298...63,448,371

G

myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11

CTD Direct Evidence: marker/mechanism

NCBI chr 3:95,125,852...95,139,486
Ensembl chr 3:95,126,446...95,139,482

G

myelocytomatosis oncogene

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Burkitt lymphoma
OMIM:113970
DNA:mutations:exons:multiple (human)

CTD
ClinVar
MouseDO
OMIM
RGD

PMID:8220424 PMID:25157968 PMID:27993330 PMID:8220424 PMID:8397370

RGD:1601453, RGD:10059619

NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223

G

pre B cell leukemia homeobox 1

CTD Direct Evidence: marker/mechanism

PMID:1967982 PMID:17244677

NCBI chr 1:167,946,933...168,259,898
Ensembl chr 1:167,946,933...168,259,839

G

pyruvate carboxylase

CTD Direct Evidence: marker/mechanism

NCBI chr19:4,560,500...4,671,780
Ensembl chr19:4,560,500...4,671,780

G

phosphoinositide-3-kinase regulatory subunit 1

CTD Direct Evidence: marker/mechanism

NCBI chr13:101,817,269...101,904,725
Ensembl chr13:101,817,071...101,904,725

G

ret proto-oncogene

CTD Direct Evidence: marker/mechanism

NCBI chr 6:118,128,709...118,174,705
Ensembl chr 6:118,128,706...118,174,679

G

spalt like transcription factor 3

CTD Direct Evidence: marker/mechanism

NCBI chr18:81,010,204...81,030,236
Ensembl chr18:81,009,591...81,029,986

G

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4

CTD Direct Evidence: marker/mechanism

NCBI chr 9:21,527,377...21,615,526
Ensembl chr 9:21,527,465...21,615,526

G

transcription factor 3

CTD Direct Evidence: marker/mechanism

PMID:1967982 PMID:17244677

NCBI chr10:80,245,375...80,269,814
Ensembl chr10:80,245,348...80,269,481

central nervous system lymphoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

Bruton agammaglobulinemia tyrosine kinase

ameliorates

RGD

NCBI chr X:133,443,083...133,484,366
Ensembl chr X:133,443,085...133,484,319

G

CD79B antigen

treatment

RGD

NCBI chr11:106,202,167...106,205,388
Ensembl chr11:106,202,167...106,205,588

G

interleukin 10

DNA:SNP:promoter:-1082G>A (human)

RGD

NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711

G

myeloid differentiation primary response gene 88

treatment

RGD

NCBI chr 9:119,165,000...119,169,084
Ensembl chr 9:119,165,000...119,170,477

childhood acute lymphocytic leukemia

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

CCCTC-binding factor

disease_progression

mRNA, protein:increased expression:bone marrow, blood (human)

RGD

NCBI chr 8:106,351,135...106,409,554
Ensembl chr 8:106,363,200...106,409,554

chronic lymphocytic leukemia

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

adenylate kinase 3

protein:increased expression:peripheral blood mononuclear cell

RGD

NCBI chr19:28,968,715...29,026,122
Ensembl chr19:28,998,233...29,025,361

G

Rho GTPase activating protein 44

mRNA:increased expression: (human)

RGD

NCBI chr11:64,892,865...65,053,779
Ensembl chr11:64,892,865...65,053,787

G

Braf transforming gene

ClinVar Annotator: match by term: Chronic lymphatic leukemia

PMID:12068308 PMID:12198537 PMID:12960123 PMID:14612909 PMID:14679157 More...

NCBI chr 6:39,580,171...39,702,592
Ensembl chr 6:39,580,171...39,702,397

G

CD40 ligand

protein:increased expression:serum (human)

RGD

NCBI chr X:56,257,448...56,269,402
Ensembl chr X:56,257,503...56,269,402

G

CD79B antigen

protein:decreased expression:peripheral blood cells (human)
mRNA, protein:splice variants, alternative forms:exon 3 (human)
protein:decreased expression:blood, B cell (human)
protein:decreased expression:blood cells (human)

RGD

PMID:10516749 PMID:10090943 PMID:10329919 PMID:10753858

RGD:151665125, RGD:151665190, RGD:11531139, RGD:151665152

NCBI chr11:106,202,167...106,205,388
Ensembl chr11:106,202,167...106,205,588

G

CD86 antigen

DNA:hypermethylation (human)

RGD

NCBI chr16:36,389,318...36,486,439
Ensembl chr16:36,424,231...36,486,443

G

F-box and WD-40 domain protein 7

ClinVar Annotator: match by term: Chronic lymphatic leukemia

PMID:25741868 PMID:26619011

NCBI chr 3:84,721,901...84,886,505
Ensembl chr 3:84,722,575...84,886,505

G

Harvey rat sarcoma virus oncogene

ClinVar Annotator: match by term: Chronic lymphatic leukemia

PMID:12835555 PMID:16329078 PMID:16372351 PMID:16835863 PMID:17211612 More...

NCBI chr 7:140,770,839...140,773,938
Ensembl chr 7:140,769,018...140,773,918

G

interleukin 5

protein:increased expression:serum

RGD

NCBI chr11:53,611,621...53,615,930
Ensembl chr11:53,611,621...53,615,933

G

interferon regulatory factor 4

disease_progression

DNA:SNPs:3' utr:multiple
DNA:SNP: :rs872071 (human)
DNA:missense mutation:exon:p.L116R (human)

RGD

PMID:23897826 PMID:20123861 PMID:20731705 PMID:23926303 PMID:20090783 More...

RGD:11526156, RGD:11530031, RGD:11530029, RGD:11530026, RGD:11530021, RGD:11526158

NCBI chr13:30,933,191...30,950,965
Ensembl chr13:30,933,209...30,950,959

G

Kirsten rat sarcoma viral oncogene homolog

ClinVar Annotator: match by term: Chronic lymphatic leukemia

PMID:2278970 PMID:3122217 PMID:12460918 PMID:15696205 PMID:16361624 More...

NCBI chr 6:145,162,425...145,197,631
Ensembl chr 6:145,162,425...145,195,965

G

leucine rich repeat containing 56

ClinVar Annotator: match by term: Chronic lymphatic leukemia

PMID:12835555 PMID:16329078 PMID:16372351 PMID:16835863 PMID:17211612 More...

NCBI chr 7:140,774,024...140,789,968
Ensembl chr 7:140,774,070...140,789,968

G

microRNA 155

miRNA:increased expression:peripheral blood mononuclear cell

RGD

NCBI chr16:84,511,028...84,511,092
Ensembl chr16:84,511,028...84,511,092

G

microRNA 21a

miRNA:increased expression:peripheral blood mononuclear cell

RGD

NCBI chr11:86,474,893...86,474,984
Ensembl chr11:86,474,893...86,474,984

G

myelocytomatosis oncogene

disease_progression

RGD

NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223

G

myeloid differentiation primary response gene 88

ClinVar Annotator: match by term: Chronic lymphatic leukemia

PMID:21179087 PMID:22931316 PMID:23215570 PMID:23355535 PMID:26619011 More...

NCBI chr 9:119,165,000...119,169,084
Ensembl chr 9:119,165,000...119,170,477

G

neuroblastoma ras oncogene

ClinVar Annotator: match by term: Chronic lymphatic leukemia

PMID:1654209 PMID:2278970 PMID:2674680 PMID:3122217 PMID:6587382 More...

NCBI chr 3:102,965,643...102,975,230
Ensembl chr 3:102,965,601...102,975,230

G

paraoxonase 1

susceptibility

DNA:missense mutations:cds:p.L55M, p.Q192R (human)

RGD

NCBI chr 6:5,168,101...5,193,824
Ensembl chr 6:5,168,090...5,193,946

G

protein tyrosine phosphatase, non-receptor type 11

ClinVar Annotator: match by term: Chronic lymphatic leukemia

PMID:12717436 PMID:14644997 PMID:15385933 PMID:15710330 PMID:15928039 More...

NCBI chr 5:121,268,596...121,329,460
Ensembl chr 5:121,268,596...121,329,460

G

protein tyrosine phosphatase, non-receptor type 22 (lymphoid)

susceptibility

DNA:snp:cds:p.R620W (rs2476601) (human)
protein:increased expression:B cell (human)

RGD

PMID:23287625 PMID:22569400

RGD:11533998, RGD:11535006

NCBI chr 3:103,763,891...103,819,568
Ensembl chr 3:103,767,111...103,819,563

G

splicing factor 3b, subunit 1

ClinVar Annotator: match by term: Chronic lymphatic leukemia

NCBI chr 1:55,024,328...55,066,660
Ensembl chr 1:55,024,328...55,066,640

G

splicing factor 3b, subunit 2

ClinVar Annotator: match by term: Chronic lymphatic leukemia

NCBI chr19:5,323,949...5,345,485
Ensembl chr19:5,323,960...5,345,483

G

signal transducer and activator of transcription 3

protein:increased phosphorylation:peripheral blood mononuclear cell

RGD

NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366

G

transformation related protein 53

ClinVar Annotator: match by term: Chronic lymphatic leukemia

PMID:253702 PMID:1565143 PMID:1565144 PMID:1631137 PMID:1683921 More...

NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699

G

exportin 1

ClinVar Annotator: match by term: Chronic lymphatic leukemia

NCBI chr11:23,205,768...23,248,250
Ensembl chr11:23,206,055...23,248,249

diffuse large B-cell lymphoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP-binding cassette, sub-family B member 1A

CTD Direct Evidence: marker/mechanism

NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575

G

ATP binding cassette subfamily G member 2 (Junior blood group)

CTD Direct Evidence: marker/mechanism

NCBI chr 6:58,561,476...58,669,436
Ensembl chr 6:58,561,508...58,672,661

G

anaplastic lymphoma kinase

CTD Direct Evidence: marker/mechanism

NCBI chr17:72,174,206...72,911,719
Ensembl chr17:72,175,967...72,911,622

G

beta-2 microglobulin

CTD Direct Evidence: marker/mechanism

NCBI chr 2:121,978,168...121,983,563
Ensembl chr 2:121,978,167...121,983,564

G

BCAS2 pre-mRNA processing factor

CTD Direct Evidence: marker/mechanism

NCBI chr 3:103,078,971...103,086,479
Ensembl chr 3:103,078,971...103,086,482

G

B cell leukemia/lymphoma 2

CTD Direct Evidence: marker/mechanism

NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004

G

BCL2-like 2

disease_progression

RGD

NCBI chr14:55,120,900...55,125,691
Ensembl chr14:55,120,834...55,125,691

G

B cell leukemia/lymphoma 6

disease_progression

diffuse large B-cell lymphoma

RGD

PMID:11821949 PMID:15701085

RGD:1600111, RGD:11530023

NCBI chr16:23,780,058...23,807,602
Ensembl chr16:23,783,802...23,807,602

G

Braf transforming gene

ClinVar Annotator: match by term: Diffuse large B cell lymphoma

NCBI chr 6:39,580,171...39,702,592
Ensembl chr 6:39,580,171...39,702,397

G

breast cancer 2, early onset

ClinVar Annotator: match by term: Diffuse large B cell lymphoma

PMID:9150172 PMID:18489799 PMID:20104584 PMID:21138478 PMID:22798144 More...

NCBI chr 5:150,445,759...150,493,612
Ensembl chr 5:150,446,095...150,493,794

G

Bruton agammaglobulinemia tyrosine kinase

ClinVar Annotator: match by term: Diffuse large B cell lymphoma

PMID:24869598 PMID:25082755 PMID:25189416 PMID:25741868 PMID:27199251 More...

NCBI chr X:133,443,083...133,484,366
Ensembl chr X:133,443,085...133,484,319

G

caspase recruitment domain family, member 11

DNA:missense mutations:exons:multiple (human)
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:25049379 PMID:26192916 PMID:18323416

NCBI chr 5:140,858,109...140,986,398
Ensembl chr 5:140,858,745...140,986,337

G

catalase

CTD Direct Evidence: marker/mechanism

NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505

G

coiled-coil domain containing 86

CTD Direct Evidence: marker/mechanism

NCBI chr19:10,918,845...10,926,630
Ensembl chr19:10,918,845...10,926,630

G

CD22 antigen

treatment

RGD

NCBI chr 7:30,564,829...30,579,767
Ensembl chr 7:30,564,827...30,579,767

G

CD40 antigen

susceptibility

DNA:SNP:5' utr:c.-1C>T (rs1883832) (human)

RGD

NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868

G

CD79A antigen (immunoglobulin-associated alpha)

CTD Direct Evidence: marker/mechanism

NCBI chr 7:24,596,922...24,601,283
Ensembl chr 7:24,596,806...24,601,622

G

CD79B antigen

severity
treatment

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Diffuse large B cell lymphoma
DNA:missense mutation:multiple, exon 5 (human)
DNA:missense mutation:multiple, exon 5-6 (human)
DNA:mutation:multiple (human)

CTD
ClinVar
RGD

PMID:11160144 PMID:21173233 PMID:31402495 PMID:31609782 PMID:25347427 More...

RGD:151665203, RGD:11075852, RGD:151665133, RGD:151665120

NCBI chr11:106,202,167...106,205,388
Ensembl chr11:106,202,167...106,205,588

G

cyclin dependent kinase 1

CTD Direct Evidence: marker/mechanism

NCBI chr10:69,170,976...69,188,742
Ensembl chr10:69,170,976...69,188,768

G

cyclin dependent kinase inhibitor 2A

CTD Direct Evidence: marker/mechanism

NCBI chr 4:89,192,710...89,212,856
Ensembl chr 4:89,192,708...89,212,890

G

checkpoint kinase 2

ClinVar Annotator: match by term: Diffuse large B cell lymphoma

PMID:16199547 PMID:21876083 PMID:24713400 PMID:28492532

NCBI chr 5:110,987,668...111,022,006
Ensembl chr 5:110,987,845...111,022,011

G

clathrin heavy chain

CTD Direct Evidence: marker/mechanism

NCBI chr11:86,585,178...86,648,637
Ensembl chr11:86,585,177...86,648,391

G

CREB binding protein

ClinVar Annotator: match by term: Diffuse large B cell lymphoma

PMID:24755471 PMID:28481359 PMID:30239046 PMID:33323405

NCBI chr16:3,899,198...4,031,864
Ensembl chr16:3,899,192...4,031,861

G

dicer 1, ribonuclease type III

disease_progression

RGD

NCBI chr12:104,654,001...104,718,331
Ensembl chr12:104,654,001...104,718,211

G

DNA methyltransferase 3A

ClinVar Annotator: match by term: Diffuse large B cell lymphoma

PMID:25363760 PMID:25741868 PMID:29900417 PMID:30478443 PMID:32581362 More...

NCBI chr12:3,851,559...3,964,442
Ensembl chr12:3,856,007...3,964,443

G

ets variant 6

ClinVar Annotator: match by term: Diffuse large B cell lymphoma

NCBI chr 6:134,012,663...134,247,121
Ensembl chr 6:134,012,663...134,247,121

G

enhancer of zeste 2 polycomb repressive complex 2 subunit

CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:20081860 PMID:28438623

NCBI chr 6:47,507,208...47,613,843
Ensembl chr 6:47,507,073...47,572,275

G

Fas cell surface death receptor

CTD Direct Evidence: marker/mechanism

NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172

G

Fc receptor, IgG, low affinity III

disease_progression

DNA:SNP: :rs1801274 (human)

RGD

NCBI chr 1:170,878,738...170,893,477
Ensembl chr 1:170,878,743...170,892,504

G

forkhead box O1

ClinVar Annotator: match by term: Diffuse large B cell lymphoma

PMID:26314988 PMID:29721381 PMID:35079069

NCBI chr 3:52,175,758...52,257,530
Ensembl chr 3:52,175,757...52,260,642

G

GLI-Kruppel family member GLI1

CTD Direct Evidence: marker/mechanism

NCBI chr10:127,165,751...127,177,448
Ensembl chr10:127,165,751...127,177,843

G

glutathione S-transferase, mu 1

treatment

RGD

NCBI chr 3:107,919,566...107,925,289
Ensembl chr 3:107,919,571...107,925,289

G

glutathione S-transferase, pi 1

susceptibility

DNA:SNP: :(rs1695)(human)

RGD

NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985

G

glutathione S-transferase, theta 1

severity

DNA:deletion:cds:

RGD

NCBI chr10:75,619,647...75,634,418
Ensembl chr10:75,619,647...75,634,418

G

intercellular adhesion molecule 1

disease_progression

proteion:increased expression:serum:

RGD

NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113

G

interleukin 21 receptor

diffuse large B-cell lymphoma

RGD

NCBI chr 7:125,202,424...125,232,742
Ensembl chr 7:125,202,601...125,232,742

G

IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)

CTD Direct Evidence: marker/mechanism

NCBI chr12:41,074,060...42,002,371
Ensembl chr12:41,074,089...42,002,371

G

interferon regulatory factor 4

disease_progression

RGD

NCBI chr13:30,933,191...30,950,965
Ensembl chr13:30,933,209...30,950,959

G

lysine (K)-specific methyltransferase 2D

CTD Direct Evidence: marker/mechanism

NCBI chr15:98,729,550...98,771,958
Ensembl chr15:98,729,550...98,769,085

G

MALT1 paracaspase

CTD Direct Evidence: marker/mechanism

NCBI chr18:65,564,010...65,612,138
Ensembl chr18:65,564,009...65,612,138

G

antigen identified by monoclonal antibody Ki 67

disease_progression

RGD

NCBI chr 7:135,291,513...135,318,286
Ensembl chr 7:135,291,513...135,318,090

G

methylenetetrahydrofolate reductase

susceptibility

DNA:transition, transversion, haplotype:cds:g.677C>T, g.1298A>C (human)

RGD

NCBI chr 4:148,123,534...148,144,019
Ensembl chr 4:148,123,534...148,144,008

G

myelocytomatosis oncogene

CTD Direct Evidence: marker/mechanism

NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223

G

myeloid differentiation primary response gene 88

severity

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Diffuse large B cell lymphoma
DNA:missense mutation:L265P (human)
DNA:mutation:L265P, L265S (human)

CTD
ClinVar
RGD

PMID:21179087 PMID:22931316 PMID:23215570 PMID:23355535 PMID:25049379 More...

RGD:151665203, RGD:11075852, RGD:151665120

NCBI chr 9:119,165,000...119,169,084
Ensembl chr 9:119,165,000...119,170,477

G

nibrin

ClinVar Annotator: match by term: Diffuse large B cell lymphoma

PMID:9590180 PMID:16415040 PMID:28492532

NCBI chr 4:15,955,388...15,992,589
Ensembl chr 4:15,957,925...15,992,589

G

nectin cell adhesion molecule 2

CTD Direct Evidence: marker/mechanism

NCBI chr 7:19,450,569...19,483,498
Ensembl chr 7:19,450,569...19,484,408

G

neurofibromin 1

ClinVar Annotator: match by term: Diffuse large B cell lymphoma

PMID:21390130 PMID:22158541 PMID:23292937

NCBI chr11:79,223,541...79,472,435
Ensembl chr11:79,230,519...79,472,438

G

nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha

no_association

RGD

NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432

G

nucleolar protein with MIF4G domain 1

CTD Direct Evidence: marker/mechanism

NCBI chr 5:29,637,338...29,658,504
Ensembl chr 5:29,639,662...29,662,841

G

3-phosphoinositide dependent protein kinase 1

CTD Direct Evidence: marker/mechanism

NCBI chr17:24,292,654...24,370,957
Ensembl chr17:24,292,654...24,369,898

G

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

CTD Direct Evidence: marker/mechanism

NCBI chr 3:32,451,203...32,520,256
Ensembl chr 3:32,451,820...32,522,635

G

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta

CTD Direct Evidence: marker/mechanism

NCBI chr 9:98,920,455...99,022,264
Ensembl chr 9:98,918,707...99,022,674

G

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta

CTD Direct Evidence: marker/mechanism

NCBI chr 4:149,733,625...149,787,023
Ensembl chr 4:149,733,625...149,787,028

G

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma

CTD Direct Evidence: marker/mechanism

NCBI chr12:32,223,128...32,258,675
Ensembl chr12:32,223,472...32,258,658

G

PMS1 homolog2, mismatch repair system component

ClinVar Annotator: match by term: Diffuse large B cell lymphoma

NCBI chr 5:143,846,379...143,922,538
Ensembl chr 5:143,846,782...143,870,786
Ensembl chr 5:143,846,782...143,870,786

G

PR domain containing 1, with ZNF domain

disease_progression

RGD

NCBI chr10:44,313,170...44,404,579
Ensembl chr10:44,313,173...44,404,497

G

peroxiredoxin 3

CTD Direct Evidence: marker/mechanism

NCBI chr19:60,852,504...60,862,976
Ensembl chr19:60,852,489...60,862,994

G

peroxiredoxin 4

CTD Direct Evidence: marker/mechanism

NCBI chr X:154,106,914...154,125,268
Ensembl chr X:154,106,914...154,123,750

G

protein arginine N-methyltransferase 5

CTD Direct Evidence: marker/mechanism

NCBI chr14:54,744,639...54,754,927
Ensembl chr14:54,744,644...54,754,982

G

phosphatase and tensin homolog

ClinVar Annotator: match by term: Diffuse large B cell lymphoma

PMID:10468583 PMID:10555148 PMID:10698513 PMID:10866302 PMID:10866658 More...

NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560

G

RAN GTPase activating protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr15:81,588,449...81,614,120
Ensembl chr15:81,588,449...81,629,731

G

ribosomal protein S6 kinase, polypeptide 1

CTD Direct Evidence: marker/mechanism

NCBI chr11:86,389,695...86,435,711
Ensembl chr11:86,389,697...86,435,631

G

SEC31 homolog A, COPII coat complex component

CTD Direct Evidence: marker/mechanism

NCBI chr 5:100,509,508...100,564,132
Ensembl chr 5:100,509,508...100,564,093

G

splicing factor 3a, subunit 1

ClinVar Annotator: match by term: Diffuse large B cell lymphoma

PMID:22037554 PMID:26498691 PMID:33563892

NCBI chr11:4,110,354...4,132,541
Ensembl chr11:4,110,350...4,132,541

G

S-phase kinase-associated protein 2

CTD Direct Evidence: marker/mechanism

NCBI chr15:9,112,070...9,155,512
Ensembl chr15:9,112,073...9,155,512

G

SMAD specific E3 ubiquitin protein ligase 2

NCBI chr11:106,710,887...106,811,544
Ensembl chr11:106,710,892...106,811,541

G

suppressor of cytokine signaling 1

ClinVar Annotator: match by term: Diffuse large B cell lymphoma

PMID:19734449 PMID:23296022 PMID:26336985 PMID:28302137 PMID:29625055

NCBI chr16:10,601,672...10,603,400
Ensembl chr16:10,600,104...10,603,400

G

superoxide dismutase 2, mitochondrial

CTD Direct Evidence: marker/mechanism

NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950

G

superoxide dismutase 3, extracellular

CTD Direct Evidence: marker/mechanism

NCBI chr 5:52,521,146...52,527,080
Ensembl chr 5:52,521,133...52,528,760

G

signal transducer and activator of transcription 3

ClinVar Annotator: match by term: Diffuse large B cell lymphoma

PMID:21690253 PMID:22591296 PMID:22859607 PMID:23926297 PMID:25873174 More...

NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366

G

spleen tyrosine kinase

CTD Direct Evidence: marker/mechanism

NCBI chr13:52,736,670...52,802,828
Ensembl chr13:52,737,209...52,802,828

G

transducin (beta)-like 1X-linked receptor 1

ClinVar Annotator: match by term: Diffuse large B cell lymphoma

PMID:9450851 PMID:16492805 PMID:21156281 PMID:21156282 PMID:25741868 More...

NCBI chr 3:22,130,756...22,270,758
Ensembl chr 3:22,130,816...22,270,758

G

transformation related protein 53

ClinVar Annotator: match by term: Diffuse large B cell lymphoma

MouseDO
ClinVar

PMID:1631137 PMID:1978757 PMID:8062826 PMID:8099841 PMID:8425176 More...

NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699

G

thioredoxin interacting protein

CTD Direct Evidence: marker/mechanism

NCBI chr 3:96,465,273...96,469,173
Ensembl chr 3:96,465,273...96,469,199

Enteropathy-Associated T-Cell Lymphoma

term browser