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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:lymphoma
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Accession:DOID:0060058 term browser browse the term
Definition:A hematologic cancer that affects lymphocytes that reside in the lymphatic system and in blood-forming organs. (DO)
Synonyms:exact_synonym: germinoblastic sarcoma;   germinoblastic sarcomas;   germinoblastoma;   germinoblastomas;   lymphoid cancer;   lymphomas;   malignant lymphoma;   malignant lymphomas;   reticulolymphosarcoma;   reticulolymphosarcomas
 narrow_synonym: lymphoma, somatic
 xref: EFO:0000574;   ICD10CM:C85.9;   ICDO:9590/3;   MESH:D008223;   MONDO:0005062;   NCI:C128121;   NCI:C134786;   NCI:C21602;   NCI:C3208;   NCI:C60448;   NCI:C7065



show annotations for term's descendants           Sort by:
lymphoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATM ATM serine/threonine kinase ISO DNA:missense mutation:cds:
DNA:deletion:exon:
RGD PMID:27895165 PMID:28007901 RGD:12879393, RGD:12879399 NCBI chr11:108,223,067...108,369,102
Ensembl chr11:108,222,804...108,369,102
JBrowse link
G BCL11B BCL11 transcription factor B EXP CTD Direct Evidence: marker/mechanism CTD PMID:17941976 NCBI chr14:99,169,287...99,272,197
Ensembl chr14:99,169,287...99,272,197
JBrowse link
G CCNB1 cyclin B1 ISO RGD PMID:19666607 RGD:2315935 NCBI chr 5:69,167,150...69,178,245
Ensembl chr 5:69,167,135...69,178,245
JBrowse link
G CD274 CD274 molecule EXP CTD Direct Evidence: marker/mechanism CTD PMID:28736328 NCBI chr 9:5,450,542...5,470,554
Ensembl chr 9:5,450,503...5,470,566
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A EXP CTD Direct Evidence: marker/mechanism CTD PMID:9488045 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301
JBrowse link
G CDKN2B cyclin dependent kinase inhibitor 2B EXP CTD Direct Evidence: marker/mechanism CTD PMID:9488045 NCBI chr 9:22,002,903...22,009,313
Ensembl chr 9:22,002,903...22,009,305
JBrowse link
G CHD4 chromodomain helicase DNA binding protein 4 IAGP DNA:missense mutation:CDS p.D140E (rs7479004) (human) RGD PMID:25407497 RGD:153323305 NCBI chr12:6,570,082...6,607,379
Ensembl chr12:6,570,082...6,614,524
JBrowse link
G EPHX1 epoxide hydrolase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:11406608 NCBI chr 1:225,810,124...225,845,563
Ensembl chr 1:225,810,124...225,845,563
JBrowse link
G ERCC6 ERCC excision repair 6, chromatin remodeling factor susceptibility ISO RGD PMID:11238917 RGD:11567233 NCBI chr10:49,434,881...49,539,538
Ensembl chr10:49,454,168...49,539,538
JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit IAGP ClinVar Annotator: match by term: Lymphoma ClinVar PMID:23023262 PMID:24563539 PMID:26619011 NCBI chr 7:148,807,383...148,884,291
Ensembl chr 7:148,807,257...148,884,321
JBrowse link
G HMGA1 high mobility group AT-hook 1 ISS MouseDO NCBI chr 6:34,236,873...34,246,231
Ensembl chr 6:34,236,873...34,246,231
JBrowse link
G IDH1 isocitrate dehydrogenase (NADP(+)) 1 IAGP ClinVar Annotator: match by term: Lymphoma ClinVar NCBI chr 2:208,236,227...208,255,071
Ensembl chr 2:208,236,229...208,266,074
JBrowse link
G IKZF1 IKAROS family zinc finger 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:11980663 NCBI chr 7:50,303,455...50,405,101
Ensembl chr 7:50,304,068...50,405,101
JBrowse link
G KMT2D lysine methyltransferase 2D IAGP ClinVar Annotator: match by term: Lymphoma ClinVar NCBI chr12:49,018,978...49,060,794
Ensembl chr12:49,018,975...49,060,794
JBrowse link
G KRAS KRAS proto-oncogene, GTPase EXP CTD Direct Evidence: marker/mechanism CTD PMID:9205081 NCBI chr12:25,205,246...25,250,929
Ensembl chr12:25,205,246...25,250,936
JBrowse link
G MAD1L1 mitotic arrest deficient 1 like 1 IAGP RGD PMID:11423979 RGD:1599865 NCBI chr 7:1,815,795...2,232,945
Ensembl chr 7:1,815,793...2,233,243
JBrowse link
G MALT1 MALT1 paracaspase IAGP RGD PMID:10523859 RGD:1599913 NCBI chr18:58,671,465...58,754,477
Ensembl chr18:58,671,465...58,754,477
JBrowse link
G MIR143 microRNA 143 EXP CTD Direct Evidence: therapeutic CTD PMID:28736328 NCBI chr 5:149,428,918...149,429,023
Ensembl chr 5:149,428,918...149,429,023
JBrowse link
G MIR155 microRNA 155 ISS MouseDO NCBI chr21:25,573,980...25,574,044
Ensembl chr21:25,573,980...25,574,044
JBrowse link
G MLH1 mutL homolog 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15700306 NCBI chr 3:36,993,466...37,050,846
Ensembl chr 3:36,993,226...37,050,896
JBrowse link
G MTHFR methylenetetrahydrofolate reductase EXP CTD Direct Evidence: marker/mechanism CTD PMID:16799656 NCBI chr 1:11,785,723...11,805,964
Ensembl chr 1:11,785,723...11,806,455
JBrowse link
G MTR 5-methyltetrahydrofolate-homocysteine methyltransferase EXP CTD Direct Evidence: marker/mechanism CTD PMID:16799656 NCBI chr 1:236,795,281...236,903,981
Ensembl chr 1:236,795,260...236,921,278
JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor IAGP ClinVar Annotator: match by term: Lymphoma ClinVar PMID:21179087 PMID:22931316 PMID:23215570 PMID:23355535 PMID:26619011 More... NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024
JBrowse link
G NOTCH1 notch receptor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18798262 NCBI chr 9:136,494,433...136,546,048
Ensembl chr 9:136,494,433...136,546,048
JBrowse link
G NRAS NRAS proto-oncogene, GTPase EXP CTD Direct Evidence: marker/mechanism CTD PMID:9205081 NCBI chr 1:114,704,469...114,716,771
Ensembl chr 1:114,704,469...114,716,771
JBrowse link
G NSD2 nuclear receptor binding SET domain protein 2 IAGP ClinVar Annotator: match by term: Lymphoma ClinVar PMID:25741868 NCBI chr 4:1,871,393...1,982,192
Ensembl chr 4:1,871,393...1,982,207
JBrowse link
G OGG1 8-oxoguanine DNA glycosylase EXP CTD Direct Evidence: therapeutic CTD PMID:17441966 NCBI chr 3:9,749,952...9,783,108
Ensembl chr 3:9,749,944...9,788,219
JBrowse link
G PAFAH1B2 platelet activating factor acetylhydrolase 1b catalytic subunit 2 IAGP DNA:translocation:intron:t(ll;14)(q23;q32) (human) RGD PMID:11983068 RGD:4107059 NCBI chr11:117,144,287...117,178,173
Ensembl chr11:117,144,284...117,176,894
JBrowse link
G PON1 paraoxonase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22800774 NCBI chr 7:95,297,676...95,324,532
Ensembl chr 7:95,297,676...95,324,532
JBrowse link
G PPP1R9B protein phosphatase 1 regulatory subunit 9B susceptibility ISO RGD PMID:21670604 RGD:10043812 NCBI chr17:50,133,737...50,150,677
Ensembl chr17:50,133,737...50,150,677
JBrowse link
G PSMB9 proteasome 20S subunit beta 9 IDA RGD PMID:17609424 RGD:6483350 NCBI chr 6:32,854,192...32,859,851
Ensembl chr 6:32,844,136...32,859,851
JBrowse link
G PTEN phosphatase and tensin homolog EXP CTD Direct Evidence: marker/mechanism CTD PMID:22287727 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930
JBrowse link
G PTGER4 prostaglandin E receptor 4 EXP CTD Direct Evidence: therapeutic CTD PMID:19075289 NCBI chr 5:40,679,915...40,746,800
Ensembl chr 5:40,679,915...40,693,735
JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 IAGP ClinVar Annotator: match by term: Lymphoma ClinVar PMID:11704759 PMID:11992261 PMID:12161469 PMID:12325025 PMID:12634870 More... NCBI chr12:112,418,947...112,509,918
Ensembl chr12:112,418,351...112,509,918
JBrowse link
G RAC2 Rac family small GTPase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19783987 NCBI chr22:37,225,270...37,244,269
Ensembl chr22:37,225,270...37,259,594
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit IAGP DNA:point mutation:codon 494:Glu-Asp RGD PMID:9047386 RGD:2298891 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090
JBrowse link
G RPL11 ribosomal protein L11 susceptibility ISO RGD PMID:26489471 RGD:11535971 NCBI chr 1:23,691,779...23,696,835
Ensembl chr 1:23,691,742...23,696,835
JBrowse link
G SETBP1 SET binding protein 1 IAGP ClinVar Annotator: match by term: Lymphoma ClinVar NCBI chr18:44,680,073...45,068,510
Ensembl chr18:44,680,173...45,068,510
JBrowse link
G SOX4 SRY-box transcription factor 4 ISO RGD PMID:15231650 RGD:1581305 NCBI chr 6:21,593,751...21,598,619
Ensembl chr 6:21,593,751...21,598,619
JBrowse link
G TP53 tumor protein p53 ISO
IAGP
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Lymphoma
CTD
ClinVar
PMID:1565143 PMID:1683921 PMID:1978757 PMID:7887414 PMID:8023157 More... NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546
JBrowse link
G TWF1 twinfilin actin binding protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19783987 NCBI chr12:43,793,723...43,806,317
Ensembl chr12:43,793,723...43,806,328
JBrowse link
acute biphenotypic leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DOT1L DOT1 like histone lysine methyltransferase treatment IDA RGD PMID:23801631 RGD:9588291 NCBI chr19:2,163,933...2,232,578
Ensembl chr19:2,163,933...2,232,578
JBrowse link
G RNF20 ring finger protein 20 disease_progression ISO RGD PMID:23412334 RGD:9831405 NCBI chr 9:101,533,853...101,563,344
Ensembl chr 9:101,533,853...101,563,344
JBrowse link
acute leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit IAGP ClinVar Annotator: match by term: Mixed Phenotype Acute Leukemia, T/Myeloid, Not Otherwise Specified ClinVar PMID:7585650 PMID:8571952 PMID:9195225 PMID:9238033 PMID:15982307 More... NCBI chr19:45,349,837...45,370,573
Ensembl chr19:45,349,837...45,370,918
JBrowse link
acute lymphoblastic leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 susceptibility IAGP
EXP
DNA:snps, haplotype:multiple (human)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:22674224 PMID:22674224 RGD:8657089 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 treatment IAGP DNA:SNP:5'UTR:rs717620(human)
DNA:SNPs: :rs717620(human)
RGD PMID:24404132 PMID:25007187 RGD:11080959, RGD:11080979 NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594
JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) disease_progression IEP mRNA:increased expression:mononuclear cell: RGD PMID:15521915 PMID:12100141 RGD:11081076, RGD:11081143 NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628
JBrowse link
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase EXP CTD Direct Evidence: marker/mechanism CTD PMID:11984797 PMID:21898527 NCBI chr 9:130,713,043...130,887,675
Ensembl chr 9:130,713,043...130,887,675
JBrowse link
G ABO ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase susceptibility IAGP RGD PMID:17065136 RGD:11100012 NCBI chr 9:133,250,401...133,275,201
Ensembl chr 9:133,233,278...133,276,024
JBrowse link
G AICDA activation induced cytidine deaminase treatment IEP RGD PMID:19759560 RGD:11039451 NCBI chr12:8,602,170...8,612,859
Ensembl chr12:8,602,155...8,613,242
JBrowse link
G ARID5B AT-rich interaction domain 5B EXP CTD Direct Evidence: marker/mechanism CTD PMID:19684603 PMID:19684604 NCBI chr10:61,901,699...62,096,944
Ensembl chr10:61,901,684...62,096,944
JBrowse link
G ARNT aryl hydrocarbon receptor nuclear translocator EXP CTD Direct Evidence: marker/mechanism CTD PMID:22674224 NCBI chr 1:150,809,713...150,876,599
Ensembl chr 1:150,809,713...150,876,708
JBrowse link
G BAX BCL2 associated X, apoptosis regulator IAGP
EXP
CTD Direct Evidence: marker/mechanism OMIM
CTD
NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BCL2 BCL2 apoptosis regulator severity IEP mRNA:increased expression:bone marrow (human) RGD PMID:25982455 RGD:11076595 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BCL2L1 BCL2 like 1 treatment IDA
IEP
mRNA:increased expression:blood, mononuclear cell (human) RGD PMID:12469194 PMID:19020783 RGD:11353852, RGD:11353866 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989
JBrowse link
G BCR BCR activator of RhoGEF and GTPase IAGP
EXP
CTD Direct Evidence: marker/mechanism OMIM
CTD
NCBI chr22:23,180,509...23,318,037
Ensembl chr22:23,179,704...23,318,037
JBrowse link
G CASP8 caspase 8 EXP CTD Direct Evidence: therapeutic CTD PMID:22010212 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836
JBrowse link
G CAST calpastatin IEP protein:increased expresssion:B cell RGD PMID:11264179 RGD:5509822 NCBI chr 5:95,961,429...96,774,683
Ensembl chr 5:96,525,267...96,779,595
Ensembl chr 5:96,525,267...96,779,595
JBrowse link
G CCND1 cyclin D1 IEP mRNA:increased expression:bone marrow (human) RGD PMID:22391157 RGD:11352824 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
JBrowse link
G CD40LG CD40 ligand ISO RGD PMID:9292526 RGD:11352271 NCBI chr  X:136,648,158...136,660,390
Ensembl chr  X:136,648,158...136,660,390
JBrowse link
G CD46 CD46 molecule IEP protein:increased expression:peripheral blood mononuclear cell (human) RGD PMID:16353080 RGD:11352810 NCBI chr 1:207,752,038...207,795,516
Ensembl chr 1:207,752,037...207,795,513
JBrowse link
G CD79B CD79b molecule IEP protein:decreased expression:bone marrow, mononuclear cell (human) RGD PMID:21487112 RGD:11250414 NCBI chr17:63,928,740...63,932,331
Ensembl chr17:63,928,738...63,932,336
JBrowse link
G CD86 CD86 molecule severity IEP protein:increased expression:peripheral blood, bone marrow, mononuclear cell (human) RGD PMID:24283754 RGD:11354967 NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139
JBrowse link
G CDK6 cyclin dependent kinase 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24736461 NCBI chr 7:92,604,921...92,836,573
Ensembl chr 7:92,604,921...92,836,573
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A disease_progression
susceptibility
no_association
IAGP
EXP
IEP
DNA:deletion: :
ClinVar Annotator: match by term: Acute lymphocytic leukemia
ClinVar Annotator: match by term: Acute lymphoid leukemia
CTD Direct Evidence: marker/mechanism
DNA:missense mutations:cds:
ClinVar
CTD
RGD
PMID:7566978 PMID:7647780 PMID:7718873 PMID:7987387 PMID:8573142 More... RGD:11251764, RGD:11057958, RGD:11252082, RGD:11252081 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301
JBrowse link
G CDKN2B cyclin dependent kinase inhibitor 2B IAGP ClinVar Annotator: match by term: Acute lymphoid leukemia ClinVar PMID:27993330 NCBI chr 9:22,002,903...22,009,313
Ensembl chr 9:22,002,903...22,009,305
JBrowse link
G CDKN2B-AS1 CDKN2B antisense RNA 1 IAGP ClinVar Annotator: match by term: Acute lymphoid leukemia ClinVar PMID:27993330 NCBI chr 9:21,994,791...22,128,142
Ensembl chr 9:21,994,139...22,128,103
JBrowse link
G CEBPE CCAAT enhancer binding protein epsilon EXP CTD Direct Evidence: marker/mechanism CTD PMID:19684604 NCBI chr14:23,117,306...23,119,255
Ensembl chr14:23,117,036...23,120,256
JBrowse link
G CFB complement factor B IAGP DNA:missense mutation:p.R32Q b(human) RGD PMID:6958349 RGD:11041155 NCBI chr 6:31,946,095...31,952,084
Ensembl chr 6:31,945,650...31,952,086
JBrowse link
G CREBBP CREB binding protein disease_progression IAGP DNA:mutations:multiple RGD PMID:25917266 RGD:11060149 NCBI chr16:3,725,054...3,880,713
Ensembl chr16:3,725,054...3,880,713
JBrowse link
G CRLF2 cytokine receptor like factor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19838194 NCBI chr  X:1,190,490...1,212,649
NCBI chr  Y:1,190,490...1,212,649
Ensembl chr  Y:1,190,490...1,212,723
Ensembl chr  X:1,190,490...1,212,723
JBrowse link
G CSF3 colony stimulating factor 3 treatment IDA RGD PMID:9250830 RGD:11039038 NCBI chr17:40,015,440...40,017,813
Ensembl chr17:40,015,361...40,017,813
JBrowse link
G CSPG4 chondroitin sulfate proteoglycan 4 severity IEP RGD PMID:8562939 RGD:734840 NCBI chr15:75,674,322...75,713,466
Ensembl chr15:75,674,322...75,712,848
JBrowse link
G CYBA cytochrome b-245 alpha chain IEP mRNA:increased expression:peripheral blood mononuclear cell: RGD PMID:19222940 RGD:11040545 NCBI chr16:88,643,289...88,651,053
Ensembl chr16:88,643,275...88,651,083
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 susceptibility
no_association
IAGP DNA:polymorphism:3"UTR:rs4646903(human)
DNA:polymorphism:3'UTR:3801T>C(human)
DNA:polymorphism:cds:2452C>A(p.T461N)(human)
RGD PMID:22964275 PMID:16676594 PMID:23725389 RGD:11352714, RGD:11352728, RGD:11352725 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22674224 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607
JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22674224 NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902
JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22674224 NCBI chr10:95,036,772...95,069,497
Ensembl chr10:95,036,772...95,069,497
JBrowse link
G CYP2D6 cytochrome P450 family 2 subfamily D member 6 susceptibility IAGP DNA:polymorphisms: :
DNA:SNP,deletion:splice junction,exon:1934G>A(human)
RGD PMID:11037802 PMID:19593802 RGD:11352820, RGD:11252111 NCBI chr22:42,126,499...42,130,810
Ensembl chr22:42,126,499...42,130,865
JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:11774269 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220
JBrowse link
G CYP3A5 cytochrome P450 family 3 subfamily A member 5 disease_progression
susceptibility
IEP
IAGP
DNA:polymorphism: : RGD PMID:19650988 PMID:22215203 RGD:11353796, RGD:11353805 NCBI chr 7:99,648,194...99,679,996
Ensembl chr 7:99,648,194...99,679,996
JBrowse link
G DHFR dihydrofolate reductase disease_progression IAGP
IEP
DNA:polymorphisms, haplotype:promoter:
DNA:polymorphisms: :-317A>G, 829C>T (human)
RGD PMID:19861437 PMID:12972803 PMID:22969948 PMID:9226157 RGD:11039542, RGD:11039545, RGD:11039544, RGD:11039543 NCBI chr 5:80,626,226...80,654,983
Ensembl chr 5:80,626,226...80,654,983
JBrowse link
G DNMT3A DNA methyltransferase 3 alpha treatment IAGP DNA:mutations:exon, intron:p.R882(human) RGD PMID:25242092 RGD:11041125 NCBI chr 2:25,227,874...25,342,590
Ensembl chr 2:25,227,855...25,342,590
JBrowse link
G DNTT DNA nucleotidylexotransferase IEP protein:increased activity:peripheral blood,bone marrow: RGD PMID:7020399 RGD:8694149 NCBI chr10:96,304,434...96,338,564
Ensembl chr10:96,304,409...96,338,564
JBrowse link
G DPYD dihydropyrimidine dehydrogenase no_association
disease_progression
IAGP DNA:SNP: :85T>C (human)
DNA:SNPs: :2194G>A, 1156G>T (human)
DNA:splice-site mutation:intron:IVS14+1G>A (human)
RGD PMID:26846104 PMID:26846104 PMID:26846104 RGD:11098453, RGD:11098453, RGD:11098453 NCBI chr 1:97,077,743...97,921,059
Ensembl chr 1:97,077,743...97,995,000
JBrowse link
G DUX4 double homeobox 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27776115 NCBI chr 4:190,173,774...190,185,911
Ensembl chr 4:190,173,774...190,185,942
JBrowse link
G EHMT1 euchromatic histone lysine methyltransferase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:32889036 NCBI chr 9:137,619,005...137,836,127
Ensembl chr 9:137,618,992...137,870,016
JBrowse link
G EHMT2 euchromatic histone lysine methyltransferase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:32889036 NCBI chr 6:31,879,759...31,897,698
Ensembl chr 6:31,879,759...31,897,698
JBrowse link
G ENG endoglin disease_progression IEP RGD PMID:17572488 RGD:11041565 NCBI chr 9:127,815,016...127,854,658
Ensembl chr 9:127,811,130...127,854,773
JBrowse link
G EPHX1 epoxide hydrolase 1 susceptibility
no_association
IAGP
EXP
DNA:missense mutation, haplotype:exon:p.Y113H (human)
CTD Direct Evidence: marker/mechanism
DNA:SNPs:exon:rs1051740, rs2234922 (human)
DNA:polymorphisms:exon
DNA:missense mutation, haplotype:exon:p.H139R (human)
CTD
RGD
PMID:21983886 PMID:21983886 PMID:22200898 PMID:22930568 PMID:19593802 More... RGD:11252110, RGD:11252114, RGD:11252113, RGD:11252111, RGD:11252110 NCBI chr 1:225,810,124...225,845,563
Ensembl chr 1:225,810,124...225,845,563
JBrowse link
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit susceptibility IAGP DNA:SNPs: :8092C>A, 19007G>A (human)
DNA:SNPs, haplotypes: :p.R194W, p.R280H, p.R399Q (human)
RGD PMID:16723154 PMID:16435384 RGD:11252160, RGD:11340204 NCBI chr19:45,407,334...45,451,547
Ensembl chr19:45,407,334...45,478,828
JBrowse link
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit no_association IAGP DNA:missense mutations: :p.D312N, p.K751Q (human)
DNA:haplotype
RGD PMID:19101034 PMID:21987080 RGD:11252192, RGD:11340201 NCBI chr19:45,349,837...45,370,573
Ensembl chr19:45,349,837...45,370,918
JBrowse link
G ERG ETS transcription factor ERG EXP
IAGP
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Acute lymphoid leukemia
CTD
ClinVar
PMID:27776115 PMID:27993330 NCBI chr21:38,367,261...38,661,783
Ensembl chr21:38,380,027...38,661,780
JBrowse link
G ETV6 ETS variant transcription factor 6 EXP
IAGP
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Acute lymphoid leukemia
CTD
ClinVar
PMID:17255265 PMID:26102509 NCBI chr12:11,649,674...11,895,377
Ensembl chr12:11,649,674...11,895,377
JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit ISS OMIM:247640 | OMIM:613065 | OMIM:613067 | OMIM:615545 MouseDO NCBI chr 7:148,807,383...148,884,291
Ensembl chr 7:148,807,257...148,884,321
JBrowse link
G F3 coagulation factor III, tissue factor IEP RGD PMID:8429686 RGD:11340211 NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759
JBrowse link
G FAS Fas cell surface death receptor disease_progression IEP protein:increased expression:CD34+ bone marrow cell RGD PMID:10500800 PMID:9711907 RGD:11049148, RGD:11049157 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605
JBrowse link
G FGA fibrinogen alpha chain IEP protein:increased expression:serum (human) RGD PMID:25317080 RGD:11040558 NCBI chr 4:154,583,126...154,590,742
Ensembl chr 4:154,583,126...154,590,742
JBrowse link
G FLT3 fms related receptor tyrosine kinase 3 IAGP
EXP
ClinVar Annotator: match by term: Acute lymphoid leukemia
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
OMIM
PMID:11290608 PMID:11442493 PMID:14604974 PMID:14670924 PMID:15256420 More... NCBI chr13:28,003,274...28,100,576
Ensembl chr13:28,003,274...28,100,592
JBrowse link
G FPGS folylpolyglutamate synthase EXP CTD Direct Evidence: marker/mechanism CTD PMID:25013492 NCBI chr 9:127,802,858...127,814,506
Ensembl chr 9:127,794,597...127,814,327
JBrowse link
G GATA3 GATA binding protein 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:35115686 NCBI chr10:8,045,333...8,075,198
Ensembl chr10:8,045,378...8,075,198
JBrowse link
G GFI1B growth factor independent 1B transcriptional repressor IEP mRNA:increased expression:blood: RGD PMID:19360458 RGD:11040460 NCBI chr 9:132,945,531...132,993,434
Ensembl chr 9:132,944,000...132,991,687
JBrowse link
G GH1 growth hormone 1 treatment IDA RGD PMID:2494952 RGD:11352727 NCBI chr17:63,917,203...63,918,839
Ensembl chr17:63,917,200...63,918,839
JBrowse link
G GNB1 G protein subunit beta 1 IAGP
EXP
ClinVar Annotator: match by term: Lymphoblastic leukemia
ClinVar Annotator: match by term: Acute lymphoid leukemia
ClinVar Annotator: match by term: Acute lymphoblastic leukemia
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
OMIM
PMID:25485910 PMID:25741868 PMID:27108799 PMID:28492532 PMID:32134617 More... NCBI chr 1:1,785,286...1,891,087
Ensembl chr 1:1,785,285...1,892,292
JBrowse link
G GPI glucose-6-phosphate isomerase IEP RGD PMID:6589021 RGD:11051848 NCBI chr19:34,359,718...34,402,413
Ensembl chr19:34,359,480...34,402,413
JBrowse link
G GPX1 glutathione peroxidase 1 treatment IDA RGD PMID:17317918 PMID:24698347 RGD:11352774, RGD:11352812 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605
JBrowse link
G GSR glutathione-disulfide reductase IEP RGD PMID:24191316 RGD:11059506 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
JBrowse link
G GSTM1 glutathione S-transferase mu 1 disease_progression
susceptibility
no_association
IAGP RGD PMID:10666194 PMID:14607752 PMID:12827651 PMID:15738600 RGD:10450829, RGD:10755410, RGD:10755409, RGD:10755321 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039
JBrowse link
G GSTP1 glutathione S-transferase pi 1 disease_progression
no_association
susceptibility
IAGP DNA:haplotype:cds:
DNA:polymorphism: :1578 a>G(human)
DNA:transition mutation:exon:
RGD PMID:10666194 PMID:23979883 PMID:15738600 RGD:10450829, RGD:10755417, RGD:10755321 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656
JBrowse link
G GSTT1 glutathione S-transferase theta 1 disease_progression
susceptibility
IAGP RGD PMID:10666194 PMID:14607752 RGD:10450829, RGD:10755410
G H1-2 H1.2 linker histone, cluster member susceptibility IAGP DNA:SNP, haplotype:enhancer: (rs807212) (human) RGD PMID:19806355 RGD:10755490 NCBI chr 6:26,055,740...26,056,470
Ensembl chr 6:26,055,740...26,056,470
JBrowse link
G HCK HCK proto-oncogene, Src family tyrosine kinase EXP CTD Direct Evidence: marker/mechanism CTD PMID:17344919 NCBI chr20:32,052,242...32,101,856
Ensembl chr20:32,052,197...32,101,856
JBrowse link
G HDAC1 histone deacetylase 1 disease_progression IEP mRNA:increased expression:bone marrow,blood: RGD PMID:23948281 RGD:9681454 NCBI chr 1:32,292,083...32,333,626
Ensembl chr 1:32,292,083...32,333,635
JBrowse link
G HDAC2 histone deacetylase 2 disease_progression IEP mRNA:increased expression:bone marrow,blood: RGD PMID:23948281 RGD:9681454 NCBI chr 6:113,933,028...113,971,148
Ensembl chr 6:113,933,028...114,011,308
JBrowse link
G HDAC4 histone deacetylase 4 treatment IEP RGD PMID:23948281 RGD:9681454 NCBI chr 2:239,048,168...239,401,649
Ensembl chr 2:239,048,168...239,401,654
JBrowse link
G HFE homeostatic iron regulator no_association IAGP DNA:missense mutation:cds:p.H63D (human)
DNA:missense mutation: :p.H63D (human)
DNA:missense mutation:cds:p.C282Y (human)
RGD PMID:10627122 PMID:17107905 PMID:10627122 RGD:10755557, RGD:10755558, RGD:10755557 NCBI chr 6:26,087,429...26,098,343
Ensembl chr 6:26,087,226...26,098,343
JBrowse link
G HK1 hexokinase 1 IDA protein:decreased activity:platelet RGD PMID:21921332 RGD:11353881 NCBI chr10:69,270,000...69,401,882
Ensembl chr10:69,269,984...69,401,884
JBrowse link
G HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 IAGP DNA:polymorphisms, haplotype:cds:HLA-DQA1*01 (human) RGD PMID:9744491 RGD:11041762 NCBI chr 6:32,637,406...32,655,272
Ensembl chr 6:32,628,179...32,647,062
JBrowse link
G HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 IAGP DNA:polymorphisms, haplotypes:cds:multiple
DNA:polymorphisms, haplotype:cds:HLA-DQB1*0501 (human)
RGD PMID:22434102 PMID:9744491 RGD:11041749, RGD:11041762 NCBI chr 6:32,659,467...32,666,657
Ensembl chr 6:32,659,467...32,668,383
JBrowse link
G HLF HLF transcription factor, PAR bZIP family member EXP CTD Direct Evidence: marker/mechanism CTD PMID:26214592 NCBI chr17:55,264,960...55,325,187
Ensembl chr17:55,264,960...55,325,187
JBrowse link
G HOXD4 homeobox D4 IAGP
EXP
ClinVar Annotator: match by term: Leukemia, acute lymphoblastic, susceptibility to
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
PMID:15776434 NCBI chr 2:176,151,550...176,153,226
Ensembl chr 2:176,151,550...176,153,226
JBrowse link
G IDH1 isocitrate dehydrogenase (NADP(+)) 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22674224 NCBI chr 2:208,236,227...208,255,071
Ensembl chr 2:208,236,229...208,266,074
JBrowse link
G IFNG interferon gamma susceptibility IAGP DNA:SNP: :rs2069727(human) RGD PMID:21067287 RGD:10755691 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G IKZF1 IKAROS family zinc finger 1 EXP
IAGP
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Acute lymphoid leukemia | ClinVar Annotator: match by term: Leukemia, acute lymphocytic, susceptibility to, 2
ClinVar Annotator: match by term: Acute lymphocytic leukemia | ClinVar Annotator: match by term: Acute lymphoid leukemia
DNA:SNPs: (human)
CTD
ClinVar
RGD
PMID:19684604 PMID:25741868 PMID:27993330 PMID:28492532 PMID:24786325 RGD:151347631 NCBI chr 7:50,303,455...50,405,101
Ensembl chr 7:50,304,068...50,405,101
JBrowse link
G IKZF2 IKAROS family zinc finger 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23334668 NCBI chr 2:212,999,698...213,152,456
Ensembl chr 2:212,999,691...213,152,427
JBrowse link
G IKZF3 IKAROS family zinc finger 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23334668 NCBI chr17:39,757,715...39,864,312
Ensembl chr17:39,757,718...39,864,312
JBrowse link
G IL10 interleukin 10 treatment IEP protein:decreased expression:blood RGD PMID:21653647 PMID:15860861 RGD:11049158, RGD:11049169 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G IRF4 interferon regulatory factor 4 IAGP DNA:SNP:intron:rs12203592 (human) RGD PMID:19897031 RGD:11526162 NCBI chr 6:391,752...411,443
Ensembl chr 6:391,739...411,443
JBrowse link
G ITPA inosine triphosphatase treatment
no_association
IAGP DNA:SNPs:exon:94C>A, 138G>A (human)
DNA:SNP:intron
RGD PMID:22009189 PMID:22009189 RGD:10766474, RGD:10766474 NCBI chr20:3,204,065...3,227,449
Ensembl chr20:3,208,868...3,223,870
JBrowse link
G KDM2B lysine demethylase 2B IEP mRNA:increased expression:bone marrow (human) RGD PMID:21310926 RGD:9588255 NCBI chr12:121,408,461...121,582,279
Ensembl chr12:121,429,096...121,581,023
JBrowse link
G KDM3B lysine demethylase 3B IEP protein:increased expression:bone marrow, mononuclear cell (human) RGD PMID:22615488 RGD:9586728 NCBI chr 5:138,352,685...138,437,027
Ensembl chr 5:138,352,685...138,437,028
JBrowse link
G KDM6A lysine demethylase 6A severity IAGP DNA:mutations:cds:multiple (human) RGD PMID:22377896 RGD:9684944 NCBI chr  X:44,873,188...45,112,779
Ensembl chr  X:44,873,188...45,112,779
JBrowse link
G KMT2A lysine methyltransferase 2A EXP
ISS
CTD Direct Evidence: marker/mechanism
OMIM:247640 | OMIM:613065
CTD
MouseDO
PMID:24736461 PMID:25730765 NCBI chr11:118,436,492...118,526,832
Ensembl chr11:118,436,456...118,526,832
JBrowse link
G KRAS KRAS proto-oncogene, GTPase disease_progression IAGP RGD PMID:17910045 PMID:25917266 RGD:11060148, RGD:11060149 NCBI chr12:25,205,246...25,250,929
Ensembl chr12:25,205,246...25,250,936
JBrowse link
G LMO2 LIM domain only 2 ISS OMIM:247640 | OMIM:613065 MouseDO NCBI chr11:33,858,576...33,892,076
Ensembl chr11:33,858,576...33,892,076
JBrowse link
G LOC105376032 uncharacterized LOC105376032 IAGP ClinVar Annotator: match by term: Acute lymphoid leukemia
ClinVar Annotator: match by term: Leukemia, acute lymphoblastic, susceptibility to, 3
ClinVar PMID:24013638 PMID:25741868 PMID:27993330 PMID:35094443 NCBI chr 9:37,002,193...37,009,052 JBrowse link
G LOC126860438 MED14-independent group 3 enhancer GRCh37_chr8:90959982-90961181 IAGP ClinVar Annotator: match by term: Acute lymphoid leukemia ClinVar PMID:23555315 PMID:25186627 PMID:25318351 PMID:25741868 PMID:25980754 More... NCBI chr 8:89,947,754...89,948,953 JBrowse link
G LOC126861452 CDK7 strongly-dependent group 2 enhancer GRCh37_chr12:12037195-12038394 IAGP ClinVar Annotator: match by term: Acute lymphoid leukemia ClinVar PMID:26102509 NCBI chr12:11,884,261...11,885,460 JBrowse link
G LOC130001608 ATAC-STARR-seq lymphoblastoid silent region 19815 IAGP ClinVar Annotator: match by term: Acute lymphoid leukemia ClinVar PMID:27993330 NCBI chr 9:22,008,647...22,008,846 JBrowse link
G MEFV MEFV innate immunity regulator, pyrin susceptibility IAGP DNA:polymorphisms:cds:p.E148Q,M680I(human) RGD PMID:22942567 RGD:11531121 NCBI chr16:3,242,027...3,256,633
Ensembl chr16:3,242,027...3,256,633
JBrowse link
G MTHFR methylenetetrahydrofolate reductase disease_progression
treatment
IAGP
EXP
DNA:missense mutation:cds:677C>T (p.A222V) (rs1801133) (human)
CTD Direct Evidence: marker/mechanism
DNA:missense mutation:cds:677C>T (human)
CTD
RGD
PMID:16706930 PMID:19923983 PMID:21644011 RGD:10449398, RGD:10449407 NCBI chr 1:11,785,723...11,805,964
Ensembl chr 1:11,785,723...11,806,455
JBrowse link
G MTR 5-methyltetrahydrofolate-homocysteine methyltransferase disease_progression
susceptibility
no_association
IAGP DNA:SNP::rs10925235(human)
DNA:polymorphism: :66A>G(human)
DNA:polymorphism: :2756A>G(human)
RGD PMID:26605150 PMID:21618417 PMID:15159311 PMID:22453148 RGD:11531136, RGD:11531141, RGD:11531140, RGD:11531137 NCBI chr 1:236,795,281...236,903,981
Ensembl chr 1:236,795,260...236,921,278
JBrowse link
G MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase susceptibility IAGP
EXP
DNA:haplotype:cds:
CTD Direct Evidence: marker/mechanism
DNA:SNP: :rs3776455(human)
CTD
RGD
PMID:17136115 PMID:17136115 PMID:23940529 RGD:11531133, RGD:11531135 NCBI chr 5:7,850,859...7,901,113
Ensembl chr 5:7,851,186...7,906,025
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor disease_progression IEP RGD PMID:25784651 RGD:11532748 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
JBrowse link
G NAT2 N-acetyltransferase 2 susceptibility
no_association
IAGP
EXP
DNA:polymorphisms: :
CTD Direct Evidence: marker/mechanism
DNA:polymorphisms,haplotype: :
CTD
RGD
PMID:22200898 PMID:25804798 PMID:22215203 PMID:21888617 RGD:11532767, RGD:11353805, RGD:11532769 NCBI chr 8:18,386,301...18,401,218
Ensembl chr 8:18,391,282...18,401,218
JBrowse link
G NBN nibrin IAGP
EXP
ClinVar Annotator: match by term: Acute lymphoid leukemia
ClinVar Annotator: match by term: Lymphoblastic leukemia
ClinVar Annotator: match by term: Acute lymphoblastic leukemia
ClinVar Annotator: match by term: Acute lymphocytic leukemia
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
OMIM
PMID:9590180 PMID:11325820 PMID:12353271 PMID:14559852 PMID:15338273 More... NCBI chr 8:89,933,331...89,984,667
Ensembl chr 8:89,924,515...90,003,228
JBrowse link
G NOS3 nitric oxide synthase 3 susceptibility
disease_progression
IAGP DNA:SNP: :rs3918186(human)
DNA:polymorphism, haplotype:cds,intron:P.E298D,-786T>C(human)
RGD PMID:23922896 PMID:20510681 RGD:11533639, RGD:11533646 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588
JBrowse link
G NOTCH3 notch receptor 3 ISS OMIM:247640 | OMIM:613065 MouseDO NCBI chr19:15,159,038...15,200,995
Ensembl chr19:15,159,038...15,200,995
JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 IAGP
EXP
DNA:mutation: :609C>T (human)
CTD Direct Evidence: marker/mechanism
DNA:missense mutations: :p.R139W (465C>T), p.P187S (609C>T) (human)
CTD
RGD
PMID:11774269 PMID:17332311 PMID:18444911 PMID:11774269 RGD:10769347, RGD:10769359 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
JBrowse link
G NRAS NRAS proto-oncogene, GTPase disease_progression IAGP DNA:missense mutation:cds: RGD PMID:25204082 RGD:11535045 NCBI chr 1:114,704,469...114,716,771
Ensembl chr 1:114,704,469...114,716,771
JBrowse link
G NSD2 nuclear receptor binding SET domain protein 2 EXP CTD Direct Evidence: therapeutic CTD PMID:24076604 NCBI chr 4:1,871,393...1,982,192
Ensembl chr 4:1,871,393...1,982,207
JBrowse link
G NT5C2 5'-nucleotidase, cytosolic II EXP CTD Direct Evidence: marker/mechanism CTD PMID:23377183 NCBI chr10:103,088,017...103,193,272
Ensembl chr10:103,087,185...103,277,605
JBrowse link
G NUP214 nucleoporin 214 susceptibility EXP
IAGP
CTD Direct Evidence: marker/mechanism CTD
OMIM
NCBI chr 9:131,125,586...131,234,663
Ensembl chr 9:131,125,573...131,234,663
JBrowse link
G P2RY8 P2Y receptor family member 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19838194 NCBI chr  X:1,462,581...1,537,185
NCBI chr  Y:1,462,581...1,537,185
Ensembl chr  Y:1,462,581...1,537,185
Ensembl chr  X:1,462,581...1,537,185
JBrowse link
G PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23334668 NCBI chr 8:80,967,810...81,112,068
Ensembl chr 8:80,967,810...81,112,068
JBrowse link
G PAX5 paired box 5 susceptibility IAGP
EXP
ClinVar Annotator: match by term: Leukemia, acute lymphoblastic, susceptibility to, 3
ClinVar Annotator: match by term: Acute lymphoid leukemia
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
CTD
PMID:24013638 PMID:24728327 PMID:25741868 PMID:26214592 PMID:27993330 More... NCBI chr 9:36,833,269...37,034,268
Ensembl chr 9:36,833,269...37,034,268
JBrowse link
G PON1 paraoxonase 1 susceptibility IAGP DNA:missense mutations:cds:p.L55M (rs854560), p.Q192R (rs662) (human) RGD PMID:22976839 RGD:11552580 NCBI chr 7:95,297,676...95,324,532
Ensembl chr 7:95,297,676...95,324,532
JBrowse link
G PRAME PRAME nuclear receptor transcriptional regulator severity IEP mRNA:increased expression:blood (human) RGD PMID:27275197 RGD:11535025 NCBI chr22:22,547,701...22,559,265
Ensembl chr22:22,547,701...22,559,361
JBrowse link
G PRDM14 PR/SET domain 14 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19043588 NCBI chr 8:70,051,651...70,071,252
Ensembl chr 8:70,051,651...70,071,693
JBrowse link
G PTEN phosphatase and tensin homolog ISS OMIM:247640 | OMIM:613065 | OMIM:613067 | OMIM:615545 MouseDO NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930
JBrowse link
G RB1 RB transcriptional corepressor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23334668 NCBI chr13:48,303,751...48,481,890
Ensembl chr13:48,303,744...48,599,436
JBrowse link
G RUNX1 RUNX family transcription factor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17255265 NCBI chr21:34,787,801...35,049,302
Ensembl chr21:34,787,801...36,004,667
JBrowse link
G SLC19A1 solute carrier family 19 member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17255265 NCBI chr21:45,502,517...45,563,025
Ensembl chr21:45,493,572...45,573,365
JBrowse link
G SNRPE small nuclear ribonucleoprotein polypeptide E severity IEP mRNA:decreased expression:bone marrow, blood, mononuclear cell (human) RGD PMID:23915977 RGD:10768836 NCBI chr 1:203,861,599...203,871,152
Ensembl chr 1:203,861,599...203,871,152
JBrowse link
G TAL1 TAL bHLH transcription factor 1, erythroid differentiation factor IAGP
EXP
CTD Direct Evidence: marker/mechanism OMIM
CTD
NCBI chr 1:47,216,290...47,232,335
Ensembl chr 1:47,216,290...47,232,225
JBrowse link
G TAL2 TAL bHLH transcription factor 2 IAGP
EXP
CTD Direct Evidence: marker/mechanism OMIM
CTD
NCBI chr 9:105,662,457...105,663,124
Ensembl chr 9:105,662,457...105,663,124
JBrowse link
G TCF3 transcription factor 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26214592 NCBI chr19:1,609,292...1,652,615
Ensembl chr19:1,609,291...1,652,615
JBrowse link
G TCN2 transcobalamin 2 IEP protein:altered activity:plasma: RGD PMID:8754152 RGD:11059889 NCBI chr22:30,607,174...30,627,271
Ensembl chr22:30,607,003...30,627,271
JBrowse link
G TERT telomerase reverse transcriptase IAGP
IEP
DNA:SNPs:promoter, introns:g.1296486C>T, g.12866516A>C, g.1279790G>A (rs2735940, rs2736100, rs10069690) (human) RGD PMID:23066086 PMID:15621763 RGD:11038654, RGD:11038667 NCBI chr 5:1,253,167...1,295,068
Ensembl chr 5:1,253,147...1,295,068
JBrowse link
G TM9SF2 transmembrane 9 superfamily member 2 IEP mRNA:increased expression:bone marrow, mononuclear cells (human) RGD PMID:12730115 RGD:2317244 NCBI chr13:99,501,472...99,564,048
Ensembl chr13:99,446,311...99,564,048
JBrowse link
G TP53 tumor protein p53 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23334668 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546
JBrowse link
G TPMT thiopurine S-methyltransferase treatment
no_association
IAGP DNA:SNPs:multiple
DNA:SNPs:introns:12356C>T, 16638C>T, 26354G>T (rs4449636, rs2518463, rs2842949) (human)
DNA:SNPs:exon:374C>T, 719A>G (rs2842934, rs1142345) (human)
DNA:SNPs: :multiple
RGD PMID:17164697 PMID:22009189 PMID:22009189 PMID:24499706 RGD:11038720, RGD:10766474, RGD:10766474, RGD:11038723 NCBI chr 6:18,128,311...18,155,169
Ensembl chr 6:18,128,311...18,155,077
JBrowse link
G TTC12 tetratricopeptide repeat domain 12 IDA DNA:hypermethylation:5'end:CpG dinucleotide RGD PMID:17657212 RGD:405866376 NCBI chr11:113,314,583...113,373,297
Ensembl chr11:113,314,579...113,383,544
JBrowse link
G TYMS thymidylate synthetase treatment IAGP DNA:repeats: : rs347430033(human) RGD PMID:25007187 RGD:11080979 NCBI chr18:657,653...673,578
Ensembl chr18:657,653...673,578
JBrowse link
G VPREB1 V-set pre-B cell surrogate light chain 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26214592 NCBI chr22:22,244,786...22,245,515
Ensembl chr22:22,244,780...22,245,515
JBrowse link
G XRCC1 X-ray repair cross complementing 1 susceptibility
no_association
IAGP
EXP
DNA:missense mutation, haplotype: :p.R399Q (human)
CTD Direct Evidence: marker/mechanism
DNA:missense mutation: :p.R399Q (human)
DNA:missense mutation: :p.R194W (human)
CTD
RGD
PMID:21983886 PMID:21983886 PMID:19101034 PMID:19101034 RGD:11252110, RGD:11252192, RGD:11252192 NCBI chr19:43,543,311...43,575,527
Ensembl chr19:43,543,311...43,580,473
JBrowse link
Acute Lymphoblastic Leukemia, with Lymphomatous Features term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase IAGP ClinVar Annotator: match by term: Lymphoblastic leukemia, acute, with lymphomatous features ClinVar PMID:10988075 PMID:11423618 PMID:11853795 PMID:11861307 PMID:11964322 More... NCBI chr 9:130,713,043...130,887,675
Ensembl chr 9:130,713,043...130,887,675
JBrowse link
G CRLF2 cytokine receptor like factor 2 IAGP ClinVar Annotator: match by term: Lymphoblastic leukemia, acute, with lymphomatous features ClinVar PMID:19907440 PMID:19965641 PMID:20018760 PMID:22368272 NCBI chr  X:1,190,490...1,212,649
NCBI chr  Y:1,190,490...1,212,649
Ensembl chr  Y:1,190,490...1,212,723
Ensembl chr  X:1,190,490...1,212,723
JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 susceptibility IAGP DNA:polymorphism:G15631T RGD PMID:19144407 RGD:6480472 NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398
JBrowse link
G FGFR1 fibroblast growth factor receptor 1 IAGP ClinVar Annotator: match by term: Lymphoblastic leukemia, acute, with lymphomatous features ClinVar PMID:25705862 PMID:26619011 PMID:26942290 PMID:33448156 NCBI chr 8:38,411,143...38,468,635
Ensembl chr 8:38,400,215...38,468,834
JBrowse link
G IL7R interleukin 7 receptor IAGP ClinVar Annotator: match by term: Lymphoblastic leukemia, acute, with lymphomatous features ClinVar PMID:22897847 PMID:22955920 NCBI chr 5:35,856,891...35,879,603
Ensembl chr 5:35,852,695...35,879,603
JBrowse link
G INSL6 insulin like 6 IAGP ClinVar Annotator: match by term: Lymphoblastic leukemia, acute, with lymphomatous features ClinVar PMID:18805579 PMID:19470474 PMID:20585391 PMID:22368270 PMID:22955920 NCBI chr 9:4,991,976...5,185,639
Ensembl chr 9:5,123,880...5,185,647
JBrowse link
G JAK1 Janus kinase 1 IAGP ClinVar Annotator: match by term: Lymphoblastic leukemia, acute, with lymphomatous features ClinVar PMID:16239216 PMID:19139102 PMID:19470474 PMID:19838194 PMID:20167706 More... NCBI chr 1:64,833,229...65,067,746
Ensembl chr 1:64,833,223...65,067,754
JBrowse link
G JAK2 Janus kinase 2 IAGP ClinVar Annotator: match by term: Lymphoblastic leukemia, acute, with lymphomatous features ClinVar PMID:18805579 PMID:19470474 PMID:20585391 PMID:22368270 PMID:22955920 NCBI chr 9:4,984,390...5,129,948
Ensembl chr 9:4,984,390...5,129,948
JBrowse link
G JAK3 Janus kinase 3 IAGP ClinVar Annotator: match by term: LYMPHOMATOUS ALL ClinVar PMID:10982185 PMID:16843266 PMID:18270328 PMID:20132407 PMID:20372971 More... NCBI chr19:17,824,782...17,847,982
Ensembl chr19:17,824,780...17,848,071
JBrowse link
G LOC126805749 BRD4-independent group 4 enhancer GRCh37_chr1:65312286-65313485 IAGP ClinVar Annotator: match by term: Lymphoblastic leukemia, acute, with lymphomatous features ClinVar PMID:16239216 PMID:19139102 PMID:19470474 PMID:19838194 PMID:20167706 More... NCBI chr 1:64,846,284...64,847,802 JBrowse link
adult T-cell leukemia/lymphoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BIRC5 baculoviral IAP repeat containing 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16497974 NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636
JBrowse link
G BMP6 bone morphogenetic protein 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18688853 NCBI chr 6:7,726,099...7,881,728
Ensembl chr 6:7,726,099...7,881,728
JBrowse link
G CARD11 caspase recruitment domain family member 11 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr 7:2,906,142...3,043,867
Ensembl chr 7:2,906,142...3,044,228
JBrowse link
G CCR4 C-C motif chemokine receptor 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr 3:32,951,644...32,956,349
Ensembl chr 3:32,951,644...32,956,349
JBrowse link
G CCR7 C-C motif chemokine receptor 7 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr17:40,553,769...40,565,472
Ensembl chr17:40,553,769...40,565,472
JBrowse link
G CD163 CD163 molecule disease_progression IEP protein:increased expression:lymph node tumor (human) RGD PMID:23557330 RGD:42721976 NCBI chr12:7,470,811...7,503,777
Ensembl chr12:7,470,811...7,503,893
JBrowse link
G CD274 CD274 molecule disease_progression IEP RGD PMID:27418641 RGD:41412177 NCBI chr 9:5,450,542...5,470,554
Ensembl chr 9:5,450,503...5,470,566
JBrowse link
G CD28 CD28 molecule EXP CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr 2:203,706,482...203,738,912
Ensembl chr 2:203,706,475...203,738,912
JBrowse link
G CD68 CD68 molecule disease_progression IEP protein:increased expression:lymph node tumor (human) RGD PMID:23557330 RGD:42721976 NCBI chr17:7,579,638...7,582,111
Ensembl chr17:7,579,491...7,582,111
JBrowse link
G CD80 CD80 molecule ISO RGD PMID:10590132 RGD:6902938 NCBI chr 3:119,524,293...119,559,614
Ensembl chr 3:119,524,293...119,559,614
JBrowse link
G CD86 CD86 molecule ISO RGD PMID:10590132 RGD:6902938 NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139
JBrowse link
G CSNK1A1 casein kinase 1 alpha 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr 5:149,492,982...149,551,439
Ensembl chr 5:149,492,982...149,551,471
JBrowse link
G CSNK2A1 casein kinase 2 alpha 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr20:472,498...543,790
Ensembl chr20:472,498...543,835
JBrowse link
G CSNK2B casein kinase 2 beta EXP CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr 6:31,666,080...31,670,067
Ensembl chr 6:31,665,227...31,670,343
JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr 2:203,867,771...203,873,965
Ensembl chr 2:203,853,888...203,873,965
JBrowse link
G FAS Fas cell surface death receptor susceptibility IAGP
IEP
DNA:polymorphism:promoter: -670 G>A(human)
protein:increased expression:peripheral blood mononuclear cell:
RGD PMID:17962369 PMID:7513372 RGD:11049147, RGD:11049453 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605
JBrowse link
G FOXP3 forkhead box P3 disease_progression EXP
IEP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:23962110 PMID:23797717 RGD:38456007 NCBI chr  X:49,250,438...49,264,710
Ensembl chr  X:49,250,438...49,264,800
JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase EXP CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr 6:111,660,332...111,873,452
Ensembl chr 6:111,660,332...111,873,452
JBrowse link
G GATA3 GATA binding protein 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr10:8,045,333...8,075,198
Ensembl chr10:8,045,378...8,075,198
JBrowse link
G GPR183 G protein-coupled receptor 183 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr13:99,294,539...99,307,399
Ensembl chr13:99,294,539...99,307,399
JBrowse link
G HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr 7:26,189,927...26,200,746
Ensembl chr 7:26,171,151...26,201,529
JBrowse link
G ICOS inducible T cell costimulator EXP CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr 2:203,936,763...203,961,577
Ensembl chr 2:203,936,763...203,961,577
JBrowse link
G IFNA1 interferon alpha 1 EXP CTD Direct Evidence: therapeutic CTD PMID:20370541 NCBI chr 9:21,440,439...21,441,316
Ensembl chr 9:21,440,439...21,441,316
JBrowse link
G IFNA2 interferon alpha 2 EXP CTD Direct Evidence: therapeutic CTD PMID:12560223 PMID:17077332 NCBI chr 9:21,384,255...21,385,398
Ensembl chr 9:21,384,255...21,385,398
JBrowse link
G IFNG interferon gamma treatment ISO
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:23962110 PMID:8800741 RGD:10755707 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G IKZF2 IKAROS family zinc finger 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr 2:212,999,698...213,152,456
Ensembl chr 2:212,999,691...213,152,427
JBrowse link
G IL10 interleukin 10 IEP
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:23962110 PMID:8704212 RGD:11049460 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G IL2 interleukin 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23962110 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725
JBrowse link
G IL4 interleukin 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23962110 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678
JBrowse link
G IL5 interleukin 5 disease_progression IEP protein:increased expression:serum RGD PMID:16425276 RGD:11354942 NCBI chr 5:132,541,445...132,556,815
Ensembl chr 5:132,541,445...132,556,838
JBrowse link
G IL6 interleukin 6 IEP protein:increased expression:serum (human) RGD PMID:10374863 RGD:11060275 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G IRF4 interferon regulatory factor 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr 6:391,752...411,443
Ensembl chr 6:391,739...411,443
JBrowse link
G JAK3 Janus kinase 3 IAGP DNA:missense mutations: :p.L156P, p.R172Q, p.E183G (human) RGD PMID:21821710 RGD:11531131 NCBI chr19:17,824,782...17,847,982
Ensembl chr19:17,824,780...17,848,071
JBrowse link
G MYB MYB proto-oncogene, transcription factor disease_progression IEP mRNA:splice variants:CD4+ T cell: RGD PMID:27307595 RGD:11532670 NCBI chr 6:135,181,308...135,219,172
Ensembl chr 6:135,181,308...135,219,173
JBrowse link
G NOTCH1 notch receptor 1 IAGP DNA:mutations:multiple (human) RGD PMID:16707600 RGD:1580759 NCBI chr 9:136,494,433...136,546,048
Ensembl chr 9:136,494,433...136,546,048
JBrowse link
G NRAS NRAS proto-oncogene, GTPase disease_progression ISO RGD PMID:21586752 RGD:11535055 NCBI chr 1:114,704,469...114,716,771
Ensembl chr 1:114,704,469...114,716,771
JBrowse link
G PLCG1 phospholipase C gamma 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr20:41,137,543...41,177,626
Ensembl chr20:41,136,960...41,196,801
JBrowse link
G PRKCB protein kinase C beta EXP CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr16:23,835,983...24,220,611
Ensembl chr16:23,835,983...24,220,611
JBrowse link
G STAT3 signal transducer and activator of transcription 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24090995 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568
JBrowse link
G TAL2 TAL bHLH transcription factor 2 IAGP RGD PMID:1763056 RGD:1599285 NCBI chr 9:105,662,457...105,663,124
Ensembl chr 9:105,662,457...105,663,124
JBrowse link
G TERF2 telomeric repeat binding factor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17643074 NCBI chr16:69,355,567...69,386,007
Ensembl chr16:69,355,567...69,408,571
JBrowse link
G TLX1 T cell leukemia homeobox 1 IAGP
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:1717256 PMID:1683261 RGD:1599439 NCBI chr10:101,131,300...101,137,789
Ensembl chr10:101,131,300...101,137,789
JBrowse link
G TNFSF8 TNF superfamily member 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:9058727 NCBI chr 9:114,893,343...114,930,595
Ensembl chr 9:114,893,343...114,930,595
JBrowse link
G TP53 tumor protein p53 IEA GAD PMID:15118671 RGD:1331525 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546
JBrowse link
G TP73 tumor protein p73 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr 1:3,652,516...3,736,201
Ensembl chr 1:3,652,516...3,736,201
JBrowse link
G VAV1 vav guanine nucleotide exchange factor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26437031 NCBI chr19:6,772,708...6,857,361
Ensembl chr19:6,772,708...6,857,366
JBrowse link
anaplastic large cell lymphoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALK ALK receptor tyrosine kinase TAS
EXP
DNA:translocation:fusion_protein
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:16151469 PMID:19503098 PMID:21345110 PMID:22155737 PMID:22920921 More... RGD:1600902 NCBI chr 2:29,192,774...29,921,586
Ensembl chr 2:29,192,774...29,921,586
JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17157164 NCBI chr14:102,080,742...102,139,749
Ensembl chr14:102,080,742...102,139,699
JBrowse link
G IRF4 interferon regulatory factor 4 IAGP DNA:translocation RGD PMID:18987657 RGD:11526155 NCBI chr 6:391,752...411,443
Ensembl chr 6:391,739...411,443
JBrowse link
G JUNB JunB proto-oncogene, AP-1 transcription factor subunit IEP RGD PMID:12145210 RGD:1549449 NCBI chr19:12,791,486...12,793,315
Ensembl chr19:12,791,486...12,793,315
JBrowse link
G NPM1 nucleophosmin 1 TAS DNA:translocation:fusion_protein RGD PMID:15659732 RGD:1600902 NCBI chr 5:171,387,116...171,410,900
Ensembl chr 5:171,387,116...171,411,810
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit EXP CTD Direct Evidence: marker/mechanism CTD PMID:17261581 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090
JBrowse link
G STAT3 signal transducer and activator of transcription 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22155737 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568
JBrowse link
G TNFRSF8 TNF receptor superfamily member 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:10908157 PMID:17261581 NCBI chr 1:12,063,303...12,144,207
Ensembl chr 1:12,063,303...12,144,207
JBrowse link
G TWIST1 twist family bHLH transcription factor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22155737 NCBI chr 7:19,113,047...19,117,636
Ensembl chr 7:19,020,991...19,117,636
JBrowse link
angioimmunoblastic T-cell lymphoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TET2 tet methylcytosine dioxygenase 2 IAGP ClinVar Annotator: match by term: Angioimmunoblastic T-cell lymphoma ClinVar PMID:19797729 PMID:27210295 PMID:27276561 PMID:28337768 PMID:28492532 More... NCBI chr 4:105,145,875...105,279,803
Ensembl chr 4:105,145,875...105,279,816
JBrowse link
G TET2-AS1 TET2 antisense RNA 1 IAGP ClinVar Annotator: match by term: Angioimmunoblastic T-cell lymphoma ClinVar PMID:19797729 PMID:27210295 PMID:27276561 PMID:28337768 PMID:28492532 More... NCBI chr 4:105,171,354...105,352,881
Ensembl chr 4:105,171,354...105,178,063
JBrowse link
B-cell acute lymphoblastic leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ERCC4 ERCC excision repair 4, endonuclease catalytic subunit IAGP ClinVar Annotator: match by term: Precursor B-cell acute lymphoblastic leukemia ClinVar PMID:23623386 PMID:25741868 NCBI chr16:13,920,154...13,952,348
Ensembl chr16:13,920,138...13,952,348
JBrowse link
G LOC107982234 WT1/WT1-AS bi-directional promoter region IAGP ClinVar Annotator: match by term: B Acute Lymphoblastic Leukemia ClinVar PMID:8621495 PMID:12640141 PMID:16987884 PMID:25741868 PMID:28492532 More... NCBI chr11:32,430,169...32,437,423 JBrowse link
G NF1 neurofibromin 1 IAGP ClinVar Annotator: match by term: Precursor B-cell acute lymphoblastic leukemia ClinVar PMID:9536098 PMID:17576681 PMID:23656349 PMID:25741868 PMID:28492532 NCBI chr17:31,094,927...31,377,677
Ensembl chr17:31,094,927...31,382,116
JBrowse link
G WT1 WT1 transcription factor IAGP ClinVar Annotator: match by term: B Acute Lymphoblastic Leukemia ClinVar PMID:8621495 PMID:12640141 PMID:16987884 PMID:25741868 PMID:28492532 More... NCBI chr11:32,387,775...32,435,539
Ensembl chr11:32,387,775...32,435,564
JBrowse link
B-Cell Chronic Lymphocytic Leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) susceptibility IAGP DNA:SNPs,haplotype: :rs1481012,rs2231142(human) RGD PMID:21918980 RGD:11080977 NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628
JBrowse link
G ACOXL acyl-CoA oxidase like EXP CTD Direct Evidence: marker/mechanism CTD PMID:23770605 NCBI chr 2:110,732,573...111,118,548
Ensembl chr 2:110,732,539...111,118,548
JBrowse link
G AICDA activation induced cytidine deaminase disease_progression IEP RGD PMID:21133730 RGD:11039455 NCBI chr12:8,602,170...8,612,859
Ensembl chr12:8,602,155...8,613,242
JBrowse link
G APOE apolipoprotein E disease_progression IAGP RGD PMID:18784741 RGD:11040549 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393
JBrowse link
G ATM ATM serine/threonine kinase EXP CTD Direct Evidence: marker/mechanism CTD PMID:17968022 NCBI chr11:108,223,067...108,369,102
Ensembl chr11:108,222,804...108,369,102
JBrowse link
G BCL11A BCL11 transcription factor A IAGP DNA:translocation:5' utr: (human) RGD PMID:11719382 RGD:11100004 NCBI chr 2:60,450,520...60,553,924
Ensembl chr 2:60,450,520...60,554,467
JBrowse link
G BCL2 BCL2 apoptosis regulator treatment
severity
no_association
IMP
EXP
IEP
IAGP
CTD Direct Evidence: marker/mechanism
protein:increased expression:B cell (human)
DNA:snp:promoter:g.-938C>A (human)
CTD
RGD
PMID:21750559 PMID:23770605 PMID:17296974 PMID:20001236 PMID:17959858 More... RGD:11522735, RGD:11526110, RGD:11526105, RGD:11526104 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BMF Bcl2 modifying factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:23770605 NCBI chr15:40,087,890...40,108,879
Ensembl chr15:40,087,890...40,108,892
JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase IAGP ClinVar Annotator: match by term: Leukemia, B-cell, chronic
ClinVar Annotator: match by term: B-cell chronic lymphocytic leukemia
ClinVar PMID:12068308 PMID:12198537 PMID:12692057 PMID:12960123 PMID:14612909 More... NCBI chr 7:140,713,328...140,924,929
Ensembl chr 7:140,719,327...140,924,929
JBrowse link
G BTK Bruton tyrosine kinase treatment IMP
IAGP
ClinVar Annotator: match by term: B-cell chronic lymphocytic leukemia ClinVar
RGD
PMID:24869598 PMID:25741868 PMID:28492532 PMID:23045577 RGD:11040699 NCBI chr  X:101,349,450...101,390,796
Ensembl chr  X:101,349,338...101,390,796
JBrowse link
G C11orf21 chromosome 11 open reading frame 21 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23770605 NCBI chr11:2,295,628...2,303,140
Ensembl chr11:2,295,628...2,303,049
JBrowse link
G CBL Cbl proto-oncogene severity IEP
IDA
mRNA,protein:increased expression:CD5+ B cell:
DNA:hypophosphorylation:CD5+ B cell:
RGD PMID:17804547 PMID:17804547 RGD:11038803, RGD:11038803 NCBI chr11:119,206,339...119,308,149
Ensembl chr11:119,206,298...119,313,926
JBrowse link
G CCDC50 coiled-coil domain containing 50 IDA RGD PMID:19641524 RGD:9685139 NCBI chr 3:191,329,394...191,398,659
Ensembl chr 3:191,329,085...191,398,659
JBrowse link
G CD40 CD40 molecule IMP RGD PMID:20616215 RGD:5490532 NCBI chr20:46,118,314...46,129,858
Ensembl chr20:46,118,271...46,129,863
JBrowse link
G CD40LG CD40 ligand IMP mouse-human chimeric gene in human RGD PMID:20882050 RGD:11352235 NCBI chr  X:136,648,158...136,660,390
Ensembl chr  X:136,648,158...136,660,390
JBrowse link
G CD5 CD5 molecule EXP CTD Direct Evidence: marker/mechanism CTD PMID:18006695 NCBI chr11:61,093,963...61,127,852
Ensembl chr11:61,102,489...61,127,852
JBrowse link
G CD79B CD79b molecule IEP
IAGP
protein:decreased expression:B lymphocyte, cell surface (human)
DNA:polymorphism:multiple (human)
mRNA, protein:splice variants, alternative forms:exon 3 (human)
RGD PMID:9269755 PMID:10552962 PMID:10090943 RGD:11250403, RGD:151665202, RGD:151665190 NCBI chr17:63,928,740...63,932,331
Ensembl chr17:63,928,738...63,932,336
JBrowse link
G CD86 CD86 molecule severity IEP protein:increased expression:peripheral blood mononuclear cell (human) RGD PMID:25179679 RGD:11354969 NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139
JBrowse link
G CDKN2B-AS1 CDKN2B antisense RNA 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23770605 NCBI chr 9:21,994,791...22,128,142
Ensembl chr 9:21,994,139...22,128,103
JBrowse link
G CPEB1 cytoplasmic polyadenylation element binding protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20062064 NCBI chr15:82,543,201...82,648,795
Ensembl chr15:82,543,201...82,648,861
JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 IEP protein:increased expression:T cell RGD PMID:16094420 PMID:15914560 RGD:11344923, RGD:11352246 NCBI chr 2:203,867,771...203,873,965
Ensembl chr 2:203,853,888...203,873,965
JBrowse link
G DKC1 dyskerin pseudouridine synthase 1 IEP RGD PMID:18077792 RGD:11251735 NCBI chr  X:154,762,864...154,777,689
Ensembl chr  X:154,762,742...154,777,689
JBrowse link
G DNMT3B DNA methyltransferase 3 beta IEP mRNA:decreased expression: B cell RGD PMID:15467427 RGD:9589146 NCBI chr20:32,762,385...32,809,356
Ensembl chr20:32,762,385...32,809,359
JBrowse link
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit severity IAGP DNA:SNP: :p.K751Q (rs13181) (human) RGD PMID:22739018 PMID:19484764 RGD:11252203, RGD:11252204 NCBI chr19:45,349,837...45,370,573
Ensembl chr19:45,349,837...45,370,918
JBrowse link
G FARP2 FERM, ARH/RhoGEF and pleckstrin domain protein 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20062064 NCBI chr 2:241,356,285...241,494,841
Ensembl chr 2:241,356,285...241,494,841
JBrowse link
G FAS Fas cell surface death receptor disease_progression IEP RGD PMID:12901972 RGD:11049461 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605
JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 IAGP ClinVar Annotator: match by term: Leukemia, B-cell, chronic ClinVar PMID:25741868 PMID:26619011 NCBI chr 4:152,320,544...152,536,092
Ensembl chr 4:152,320,544...152,536,092
JBrowse link
G FCGR3A Fc gamma receptor IIIa no_association IAGP DNA:SNP:exon:p.F158V (rs396991) (human) RGD PMID:14563637 RGD:11352260 NCBI chr 1:161,541,759...161,550,737
Ensembl chr 1:161,541,759...161,550,968
JBrowse link
G GNAS GNAS complex locus disease_progression IAGP DNA:polymorphism:393T>C (human) RGD PMID:17020971 RGD:1601379 NCBI chr20:58,839,748...58,911,192
Ensembl chr20:58,839,718...58,911,192
JBrowse link
G HRAS HRas proto-oncogene, GTPase IAGP ClinVar Annotator: match by term: Leukemia, B-cell, chronic
ClinVar Annotator: match by term: B-cell chronic lymphocytic leukemia
ClinVar PMID:12835555 PMID:16329078 PMID:16372351 PMID:16835863 PMID:17211612 More... NCBI chr11:532,242...535,576
Ensembl chr11:532,242...537,321
JBrowse link
G ICAM1 intercellular adhesion molecule 1 severity IEP RGD PMID:7658704 RGD:11354983 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
JBrowse link
G IFNG interferon gamma susceptibility IAGP DNA:polymorphism: :847A>T(human) RGD PMID:19757192 RGD:10755703 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G IGHV3-21 immunoglobulin heavy variable 3-21 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15817677 NCBI chr14:106,235,062...106,235,515
Ensembl chr14:106,235,064...106,235,594
JBrowse link
G IL10 interleukin 10 disease_progression
no_association
IEP
IAGP
protein:increased expression:serum
DNA:SNPs: :multiple
DNA:SNPs: :rs1800890, rs4072227, rs17015865 (human)
RGD PMID:22945689 PMID:10638947 PMID:19573080 PMID:19573080 RGD:11041895, RGD:11049174, RGD:11049165, RGD:11049165 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G IL19 interleukin 19 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18006695 NCBI chr 1:206,770,773...206,842,981
Ensembl chr 1:206,770,764...206,842,981
JBrowse link
G IL1A interleukin 1 alpha IAGP RGD PMID:19074885 RGD:11051968 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
JBrowse link
G IL1B interleukin 1 beta severity IAGP
IEP
DNA:SNP:promoter:-511C>T (human)
protein:decreased expression:plasma:
RGD PMID:18271063 PMID:10870116 RGD:11051967, RGD:11522755 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL1RN interleukin 1 receptor antagonist IEP protein:decreased expression:plasma: RGD PMID:10870116 RGD:11522755 NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016
JBrowse link
G IL6 interleukin 6 IEP
EXP
protein:increased expression:plasma:
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:18006695 PMID:10870116 RGD:11522755 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G IRF4 interferon regulatory factor 4 disease_progression IEP
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:18758461 PMID:12393648 PMID:12079517 RGD:11526160, RGD:11530024 NCBI chr 6:391,752...411,443
Ensembl chr 6:391,739...411,443
JBrowse link
G ITGA4 integrin subunit alpha 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21093051 NCBI chr 2:181,457,205...181,538,940
Ensembl chr 2:181,457,202...181,538,940
JBrowse link
G KLRC4 killer cell lectin like receptor C4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18006695 NCBI chr12:10,407,384...10,409,757
Ensembl chr12:10,407,384...10,409,757
JBrowse link
G KRAS KRAS proto-oncogene, GTPase IAGP ClinVar Annotator: match by term: Leukemia, B-cell, chronic ClinVar PMID:2278970 PMID:3122217 PMID:12460918 PMID:15696205 PMID:16361624 More... NCBI chr12:25,205,246...25,250,929
Ensembl chr12:25,205,246...25,250,936
JBrowse link
G LEF1 lymphoid enhancer binding factor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23770605 NCBI chr 4:108,047,548...108,168,932
Ensembl chr 4:108,047,545...108,168,956
JBrowse link
G LILRA4 leukocyte immunoglobulin like receptor A4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18006695 NCBI chr19:54,333,185...54,339,162
Ensembl chr19:54,333,185...54,339,162
JBrowse link
G LRRC56 leucine rich repeat containing 56 IAGP ClinVar Annotator: match by term: Leukemia, B-cell, chronic ClinVar PMID:12835555 PMID:16329078 PMID:16372351 PMID:16835863 PMID:17211612 More... NCBI chr11:506,462...554,912
Ensembl chr11:537,527...554,912
JBrowse link
G MIR143 microRNA 143 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17892514 NCBI chr 5:149,428,918...149,429,023
Ensembl chr 5:149,428,918...149,429,023
JBrowse link
G MIR145 microRNA 145 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17892514 NCBI chr 5:149,430,646...149,430,733
Ensembl chr 5:149,430,646...149,430,733
JBrowse link
G MS4A1 membrane spanning 4-domains A1 IDA RGD PMID:19911856 RGD:2316994 NCBI chr11:60,455,847...60,470,752
Ensembl chr11:60,455,846...60,470,752
JBrowse link
G MTHFR methylenetetrahydrofolate reductase EXP CTD Direct Evidence: marker/mechanism CTD PMID:16706930 NCBI chr 1:11,785,723...11,805,964
Ensembl chr 1:11,785,723...11,806,455
JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor IAGP ClinVar Annotator: match by term: Leukemia, B-cell, chronic ClinVar PMID:21179087 PMID:22931316 PMID:23215570 PMID:23355535 PMID:26619011 More... NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024
JBrowse link
G NRAS NRAS proto-oncogene, GTPase IAGP ClinVar Annotator: match by term: Leukemia, B-cell, chronic ClinVar PMID:1654209 PMID:2278970 PMID:2674680 PMID:3122217 PMID:6587382 More... NCBI chr 1:114,704,469...114,716,771
Ensembl chr 1:114,704,469...114,716,771
JBrowse link
G P2RX7 purinergic receptor P2X 7 EXP CTD Direct Evidence: marker/mechanism CTD PMID:11003599 NCBI chr12:121,132,876...121,188,032
Ensembl chr12:121,132,819...121,188,032
JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 severity IEP protein:increased expression:B cell (human) RGD PMID:12673718 RGD:11541127 NCBI chr17:64,319,415...64,390,860
Ensembl chr17:64,319,415...64,413,776
JBrowse link
G PLCG2 phospholipase C gamma 2 EXP
IAGP
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: B-cell chronic lymphocytic leukemia
CTD
ClinVar
PMID:24869598 PMID:27542411 PMID:28492532 NCBI chr16:81,779,291...81,962,685
Ensembl chr16:81,779,279...81,962,685
JBrowse link
G PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23770605 NCBI chr18:59,899,996...59,904,305
Ensembl chr18:59,899,996...59,904,305
JBrowse link
G POLB DNA polymerase beta EXP CTD Direct Evidence: marker/mechanism CTD PMID:18006695 NCBI chr 8:42,338,494...42,371,808
Ensembl chr 8:42,338,454...42,371,808
JBrowse link
G PPP2R5C protein phosphatase 2 regulatory subunit B'gamma EXP CTD Direct Evidence: marker/mechanism CTD PMID:16038780 NCBI chr14:101,760,573...101,927,992
Ensembl chr14:101,761,709...101,927,989
JBrowse link
G PRAME PRAME nuclear receptor transcriptional regulator IEP protein:increased expression:mononuclear cell (human) RGD PMID:16620968 RGD:11535021 NCBI chr22:22,547,701...22,559,265
Ensembl chr22:22,547,701...22,559,361
JBrowse link
G PRKD2 protein kinase D2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18758461 NCBI chr19:46,674,316...46,717,114
Ensembl chr19:46,674,275...46,717,127
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16314473 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 IAGP ClinVar Annotator: match by term: Leukemia, B-cell, chronic
ClinVar Annotator: match by term: B-cell chronic lymphocytic leukemia
ClinVar PMID:12161469 PMID:12717436 PMID:14644997 PMID:14982869 PMID:15385933 More... NCBI chr12:112,418,947...112,509,918
Ensembl chr12:112,418,351...112,509,918
JBrowse link
G QPCT glutaminyl-peptide cyclotransferase EXP CTD Direct Evidence: marker/mechanism CTD PMID:23770605 NCBI chr 2:37,344,630...37,373,322
Ensembl chr 2:37,342,827...37,373,322
JBrowse link
G RBL2 RB transcriptional corepressor like 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16038780 NCBI chr16:53,434,471...53,491,648
Ensembl chr16:53,433,977...53,491,648
JBrowse link
G SF3B1 splicing factor 3b subunit 1 EXP
IAGP
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: B-cell chronic lymphocytic leukemia | ClinVar Annotator: match by term: Leukemia, B-cell, chronic
CTD
ClinVar
PMID:22158541 PMID:23634996 PMID:25741868 PMID:26619011 NCBI chr 2:197,389,784...197,435,093
Ensembl chr 2:197,388,515...197,435,079
JBrowse link
G SF3B2 splicing factor 3b subunit 2 IAGP ClinVar Annotator: match by term: B-cell chronic lymphocytic leukemia | ClinVar Annotator: match by term: Leukemia, B-cell, chronic ClinVar PMID:26619011 NCBI chr11:66,052,364...66,069,308
Ensembl chr11:66,050,729...66,069,308
JBrowse link
G SP140 SP140 nuclear body protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:18758461 NCBI chr 2:230,186,151...230,316,571
Ensembl chr 2:230,203,110...230,313,215
JBrowse link
G TERT telomerase reverse transcriptase disease_progression IEP RGD PMID:17344921 RGD:11038662 NCBI chr 5:1,253,167...1,295,068
Ensembl chr 5:1,253,147...1,295,068
JBrowse link
G TFRC transferrin receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:16904380 NCBI chr 3:196,049,284...196,082,090
Ensembl chr 3:196,012,511...196,082,153
JBrowse link
G THBD thrombomodulin IEP RGD PMID:21812019 RGD:5685033 NCBI chr20:23,045,633...23,049,672
Ensembl chr20:23,045,633...23,049,672
JBrowse link
G TNF tumor necrosis factor disease_progression IEP protein:increased expression:bone marrow, blood, lymphocyte RGD PMID:12010662 PMID:22945689 RGD:10449463, RGD:11041895 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TNFRSF10A TNF receptor superfamily member 10a susceptibility IAGP DNA:missense mutation:cds:p.E228A (c.683A>C) (human)
DNA:SNP: :1322A>G (human)
RGD PMID:16217763 PMID:15531454 RGD:11038717, RGD:11038718 NCBI chr 8:23,190,452...23,225,102
Ensembl chr 8:23,190,452...23,225,102
JBrowse link
G TNFRSF11A TNF receptor superfamily member 11a EXP CTD Direct Evidence: marker/mechanism CTD PMID:16270354 NCBI chr18:62,325,310...62,391,288
Ensembl chr18:62,325,287...62,391,288
JBrowse link
G TNFSF11 TNF superfamily member 11 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16270354 NCBI chr13:42,562,736...42,608,013
Ensembl chr13:42,562,736...42,608,013
JBrowse link
G TNFSF13 TNF superfamily member 13 IEP protein:increased expression:serum RGD PMID:15488762 RGD:1549466 NCBI chr17:7,558,282...7,561,601
Ensembl chr17:7,558,292...7,561,608
JBrowse link
G TNFSF8 TNF superfamily member 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:9058727 NCBI chr 9:114,893,343...114,930,595
Ensembl chr 9:114,893,343...114,930,595
JBrowse link
G TOPBP1 DNA topoisomerase II binding protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18006695 NCBI chr 3:133,600,238...133,661,941
Ensembl chr 3:133,598,175...133,662,380
JBrowse link
G TP53 tumor protein p53 disease_progression IAGP
EXP
DNA:deletion: :
ClinVar Annotator: match by term: Leukemia, B-cell, chronic
ClinVar Annotator: match by term: B-cell chronic lymphocytic leukemia
ClinVar Annotator: match by term: B-cell chronic lymphocytic leukemia | ClinVar Annotator: match by term: Leukemia, B-cell, chronic
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
RGD
PMID:253702 PMID:1359493 PMID:1565143 PMID:1565144 PMID:1631137 More... RGD:11075074 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546
JBrowse link
G VDR vitamin D receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:12446453 NCBI chr12:47,841,537...47,904,994
Ensembl chr12:47,841,537...47,943,048
JBrowse link
G XPO1 exportin 1 IAGP ClinVar Annotator: match by term: Leukemia, B-cell, chronic ClinVar PMID:26619011 NCBI chr 2:61,477,849...61,538,612
Ensembl chr 2:61,476,032...61,538,741
JBrowse link
G XRCC1 X-ray repair cross complementing 1 severity
no_association
IAGP DNA:SNP: :p.R399Q (rs25487) (human)
DNA:SNP: :p.R194W (rs1799782), p.R280H (25489) (human)
RGD PMID:19484764 PMID:19484764 RGD:11252204, RGD:11252204 NCBI chr19:43,543,311...43,575,527
Ensembl chr19:43,543,311...43,580,473
JBrowse link
B-cell lymphoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) susceptibility IAGP DNA:SNP: :rs6857600(human) RGD PMID:21918980 RGD:11080977 NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628
JBrowse link
G AICDA activation induced cytidine deaminase ISO RGD PMID:17251349 RGD:11039449 NCBI chr12:8,602,170...8,612,859
Ensembl chr12:8,602,155...8,613,242
JBrowse link
G BCL2L2 BCL2 like 2 disease_progression ISO RGD PMID:28094768 RGD:14394511 NCBI chr14:23,306,833...23,311,751
Ensembl chr14:23,298,790...23,311,751
JBrowse link
G BCL6 BCL6 transcription repressor IAGP diffuse large B-cell lymphoma DNA:translocation:promoter,CDS:t(3;16)(q27;p11) results in IL21R promoter fused to BCL6 coding region RGD PMID:11821949 RGD:1600111 NCBI chr 3:187,721,377...187,745,468
Ensembl chr 3:187,721,377...187,745,725
JBrowse link
G BRD2 bromodomain containing 2 IMP RGD PMID:14563639 RGD:9586345 NCBI chr 6:32,968,594...32,981,505
Ensembl chr 6:32,968,594...32,981,505
JBrowse link
G BTK Bruton tyrosine kinase treatment ISO
IMP
human cell in a mouse model RGD PMID:25662332 PMID:28348046 RGD:11040764, RGD:124713554 NCBI chr  X:101,349,450...101,390,796
Ensembl chr  X:101,349,338...101,390,796
JBrowse link
G CBX7 chromobox 7 ISO RGD PMID:17374722 RGD:11352707 NCBI chr22:39,130,772...39,152,680
Ensembl chr22:39,120,167...39,152,680
JBrowse link
G CD40 CD40 molecule IMP RGD PMID:20616215 RGD:5490532 NCBI chr20:46,118,314...46,129,858
Ensembl chr20:46,118,271...46,129,863
JBrowse link
G CSF2 colony stimulating factor 2 treatment ISO RGD PMID:8469286 RGD:10450244 NCBI chr 5:132,073,789...132,076,170
Ensembl chr 5:132,073,789...132,076,170
JBrowse link
G CSF3 colony stimulating factor 3 EXP CTD Direct Evidence: therapeutic CTD PMID:11042651 NCBI chr17:40,015,440...40,017,813
Ensembl chr17:40,015,361...40,017,813
JBrowse link
G EAF2 ELL associated factor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20564326 NCBI chr 3:121,835,209...121,886,526
Ensembl chr 3:121,835,183...121,886,526
JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit severity
treatment
ISO
IMP
ISS
MouseDO
RGD
PMID:23982173 PMID:29456795 RGD:10755356, RGD:126781726 NCBI chr 7:148,807,383...148,884,291
Ensembl chr 7:148,807,257...148,884,321
JBrowse link
G IL21R interleukin 21 receptor IAGP diffuse large B-cell lymphoma DNA:translocation:promoter,CDS:t(3;16)(q27;p11) results in IL21R promoter fused to BCL6 coding region RGD PMID:11821949 RGD:1600111 NCBI chr16:27,402,174...27,452,042
Ensembl chr16:27,402,174...27,452,042
JBrowse link
G JAK3 Janus kinase 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24837469 NCBI chr19:17,824,782...17,847,982
Ensembl chr19:17,824,780...17,848,071
JBrowse link
G KAT5 lysine acetyltransferase 5 severity ISO RGD PMID:17728759 RGD:9588481 NCBI chr11:65,712,018...65,719,604
Ensembl chr11:65,711,996...65,719,604
JBrowse link
G LGALS1 galectin 1 ISO protein:increased expression:primary tumor (rat) RGD PMID:16733672 RGD:2316550 NCBI chr22:37,675,636...37,679,802
Ensembl chr22:37,675,636...37,679,802
JBrowse link
G MIR143 microRNA 143 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17892514 NCBI chr 5:149,428,918...149,429,023
Ensembl chr 5:149,428,918...149,429,023
JBrowse link
G MIR145 microRNA 145 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17892514 NCBI chr 5:149,430,646...149,430,733
Ensembl chr 5:149,430,646...149,430,733
JBrowse link
G NRAS NRAS proto-oncogene, GTPase EXP CTD Direct Evidence: marker/mechanism CTD PMID:14633661 NCBI chr 1:114,704,469...114,716,771
Ensembl chr 1:114,704,469...114,716,771
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:14654083 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
JBrowse link
G PTPN1 protein tyrosine phosphatase non-receptor type 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24531327 NCBI chr20:50,510,383...50,585,241
Ensembl chr20:50,510,321...50,585,241
JBrowse link
G STAT5A signal transducer and activator of transcription 5A ISO RGD PMID:27018255 RGD:151665817 NCBI chr17:42,287,439...42,311,943
Ensembl chr17:42,287,547...42,311,943
JBrowse link
G TNFSF8 TNF superfamily member 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:9058727 NCBI chr 9:114,893,343...114,930,595
Ensembl chr 9:114,893,343...114,930,595
JBrowse link
G TNFSF9 TNF superfamily member 9 ISO RGD PMID:10202049 RGD:2317349 NCBI chr19:6,531,026...6,535,924
Ensembl chr19:6,531,026...6,535,924
JBrowse link
B-lymphoblastic leukemia/lymphoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase treatment IMP RGD PMID:21481795 RGD:11038814 NCBI chr 9:130,713,043...130,887,675
Ensembl chr 9:130,713,043...130,887,675
JBrowse link
G AHR aryl hydrocarbon receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:35687267 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152
JBrowse link
G AKR1C3 aldo-keto reductase family 1 member C3 treatment IDA RGD PMID:26116659 RGD:11541128 NCBI chr10:5,048,781...5,107,686
Ensembl chr10:5,035,354...5,107,686
JBrowse link
G ATF7IP activating transcription factor 7 interacting protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:24413735 NCBI chr12:14,365,682...14,502,930
Ensembl chr12:14,365,676...14,502,931
JBrowse link
G BCL2L1 BCL2 like 1 severity ISO RGD PMID:18216295 RGD:11531108 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989
JBrowse link
G BCR BCR activator of RhoGEF and GTPase ISO BCR/ABL fusion RGD PMID:9310467 RGD:41404633 NCBI chr22:23,180,509...23,318,037
Ensembl chr22:23,179,704...23,318,037
JBrowse link
G BRD2 bromodomain containing 2 IMP RGD PMID:14563639 RGD:9586345 NCBI chr 6:32,968,594...32,981,505
Ensembl chr 6:32,968,594...32,981,505
JBrowse link
G CCN2 cellular communication network factor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24154679 NCBI chr 6:131,948,176...131,951,372
Ensembl chr 6:131,948,176...131,951,372
JBrowse link
G CCND1 cyclin D1 ISO mRNA:increased expression:B cell (mouse) RGD PMID:23169640 RGD:11353783 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A treatment
susceptibility
ISO
IAGP
DNA:mutation:cds:c.442C>T,p.A148T,rs3731249 (human) RGD PMID:16618932 PMID:26104880 PMID:21622646 RGD:11251751, RGD:11057958, RGD:11251772 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301
JBrowse link
G CRLF2 cytokine receptor like factor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24141364 NCBI chr  X:1,190,490...1,212,649
NCBI chr  Y:1,190,490...1,212,649
Ensembl chr  Y:1,190,490...1,212,723
Ensembl chr  X:1,190,490...1,212,723
JBrowse link
G CYP3A5 cytochrome P450 family 3 subfamily A member 5 treatment IAGP DNA:polymorphisms: : RGD PMID:21225912 RGD:11353807 NCBI chr 7:99,648,194...99,679,996
Ensembl chr 7:99,648,194...99,679,996
JBrowse link
G DUX4 double homeobox 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27019113 NCBI chr 4:190,173,774...190,185,911
Ensembl chr 4:190,173,774...190,185,942
JBrowse link
G ETV6 ETS variant transcription factor 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15217836 PMID:24413735 PMID:25807284 NCBI chr12:11,649,674...11,895,377
Ensembl chr12:11,649,674...11,895,377
JBrowse link
G F13A1 coagulation factor XIII A chain IEP protein:increased expression:B lymphoblast: RGD PMID:16894461 RGD:11041855 NCBI chr 6:6,144,084...6,320,662
Ensembl chr 6:6,144,084...6,321,013
JBrowse link
G F3 coagulation factor III, tissue factor treatment IDA RGD PMID:19874310 RGD:11341694 NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759
JBrowse link
G FH fumarate hydratase IAGP ClinVar Annotator: match by term: B Lymphoblastic Leukemia/Lymphoma, Not Otherwise Specified ClinVar PMID:25741868 PMID:28492532 NCBI chr 1:241,497,603...241,519,755
Ensembl chr 1:241,497,511...241,519,799
JBrowse link
G FLT3 fms related receptor tyrosine kinase 3 IEP mRNA,protein:increased expression:bone marrow: RGD PMID:8562934 RGD:11049466 NCBI chr13:28,003,274...28,100,576
Ensembl chr13:28,003,274...28,100,592
JBrowse link
G GATA3 GATA binding protein 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24141364 NCBI chr10:8,045,333...8,075,198
Ensembl chr10:8,045,378...8,075,198
JBrowse link
G IDO1 indoleamine 2,3-dioxygenase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:35687267 NCBI chr 8:39,913,891...39,928,790
Ensembl chr 8:39,902,275...39,928,790
JBrowse link
G IKZF1 IKAROS family zinc finger 1 disease_progression IAGP
EXP
DNA:mutations: :
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:24141364 PMID:22699455 RGD:11075072 NCBI chr 7:50,303,455...50,405,101
Ensembl chr 7:50,304,068...50,405,101
JBrowse link
G IL5 interleukin 5 ISO RGD PMID:15368290 RGD:7241068 NCBI chr 5:132,541,445...132,556,815
Ensembl chr 5:132,541,445...132,556,838
JBrowse link
G IRF4 interferon regulatory factor 4 ISO RGD PMID:25006123 PMID:20585039 PMID:21818355 RGD:11526159, RGD:11530030, RGD:11530020 NCBI chr 6:391,752...411,443
Ensembl chr 6:391,739...411,443
JBrowse link
G IRF8 interferon regulatory factor 8 ISO RGD PMID:20585039 RGD:11530030 NCBI chr16:85,899,162...85,922,609
Ensembl chr16:85,899,116...85,922,606
JBrowse link
G ISX intestine specific homeobox EXP CTD Direct Evidence: marker/mechanism CTD PMID:35687267 NCBI chr22:35,066,158...35,087,387
Ensembl chr22:35,066,136...35,087,387
JBrowse link
G LOC107982234 WT1/WT1-AS bi-directional promoter region IAGP ClinVar Annotator: match by term: Pre-B-cell acute lymphoblastic leukemia ClinVar PMID:8621495 PMID:12640141 PMID:16987884 PMID:25741868 PMID:28492532 More... NCBI chr11:32,430,169...32,437,423 JBrowse link
G LOC130062899 ATAC-STARR-seq lymphoblastoid active region 13597 IAGP ClinVar Annotator: match by term: B Lymphoblastic Leukemia/Lymphoma, Not Otherwise Specified ClinVar PMID:25741868 PMID:26080840 PMID:26295973 PMID:28492532 NCBI chr19:1,223,046...1,223,255 JBrowse link
G MGA MAX dimerization protein MGA EXP CTD Direct Evidence: marker/mechanism CTD PMID:24413735 NCBI chr15:41,621,224...41,769,940
Ensembl chr15:41,621,134...41,773,081
JBrowse link
G MYB MYB proto-oncogene, transcription factor disease_progression IEP mRNA:splice variants:cds: RGD PMID:21853052 RGD:11532669 NCBI chr 6:135,181,308...135,219,172
Ensembl chr 6:135,181,308...135,219,173
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor ISO RGD PMID:22120021 RGD:7207416 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
JBrowse link
G PAX5 paired box 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24013638 PMID:30643249 NCBI chr 9:36,833,269...37,034,268
Ensembl chr 9:36,833,269...37,034,268
JBrowse link
G PDGFRA platelet derived growth factor receptor alpha treatment ISO RGD PMID:22447844 RGD:11075097 NCBI chr 4:54,229,293...54,298,245
Ensembl chr 4:54,229,280...54,298,245
JBrowse link
G RB1 RB transcriptional corepressor 1 IAGP ClinVar Annotator: match by term: B Lymphoblastic Leukemia/Lymphoma, Not Otherwise Specified ClinVar PMID:25741868 PMID:28492532 NCBI chr13:48,303,751...48,481,890
Ensembl chr13:48,303,744...48,599,436
JBrowse link
G RUNX1 RUNX family transcription factor 1 onset IAGP DNA:amplification RGD PMID:21822204 RGD:6482828 NCBI chr21:35,372,507...35,580,764
Ensembl chr21:34,787,801...36,004,667
JBrowse link
G RUNX1 RUNX family transcription factor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15217836 PMID:24413735 NCBI chr21:34,787,801...35,049,302
Ensembl chr21:34,787,801...36,004,667
JBrowse link
G STAT3 signal transducer and activator of transcription 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19796711 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568
JBrowse link
G STAT5A signal transducer and activator of transcription 5A IEP protein:increased phosphorylation:bone marrow (human) RGD PMID:27018255 RGD:151665817 NCBI chr17:42,287,439...42,311,943
Ensembl chr17:42,287,547...42,311,943
JBrowse link
G STK11 serine/threonine kinase 11 IAGP ClinVar Annotator: match by term: B Lymphoblastic Leukemia/Lymphoma, Not Otherwise Specified ClinVar PMID:25741868 PMID:26080840 PMID:26295973 PMID:28492532 NCBI chr19:1,205,778...1,228,431
Ensembl chr19:1,177,558...1,228,431
JBrowse link
G SUFU SUFU negative regulator of hedgehog signaling IAGP ClinVar Annotator: match by term: B Lymphoblastic Leukemia/Lymphoma, Not Otherwise Specified ClinVar PMID:25741868 PMID:28492532 NCBI chr10:102,502,819...102,633,535
Ensembl chr10:102,503,972...102,633,535
JBrowse link
G TCF3 transcription factor 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19246562 NCBI chr19:1,609,292...1,652,615
Ensembl chr19:1,609,291...1,652,615
JBrowse link
G TDO2 tryptophan 2,3-dioxygenase EXP CTD Direct Evidence: marker/mechanism CTD PMID:35687267 NCBI chr 4:155,903,696...155,920,406
Ensembl chr 4:155,854,738...155,920,406
JBrowse link
G TFPI tissue factor pathway inhibitor treatment IDA RGD PMID:19874310 RGD:11341694 NCBI chr 2:187,464,230...187,554,435
Ensembl chr 2:187,464,230...187,565,760
JBrowse link
G TNFSF13 TNF superfamily member 13 IMP RGD PMID:15488762 RGD:1549466 NCBI chr17:7,558,282...7,561,601
Ensembl chr17:7,558,292...7,561,608
JBrowse link
G TNFSF8 TNF superfamily member 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:9058727 NCBI chr 9:114,893,343...114,930,595
Ensembl chr 9:114,893,343...114,930,595
JBrowse link
G TP53 tumor protein p53 disease_progression IAGP DNA:mutations: : RGD PMID:22699455 RGD:11075072 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546
JBrowse link
G WT1 WT1 transcription factor IAGP ClinVar Annotator: match by term: Pre-B-cell acute lymphoblastic leukemia ClinVar PMID:8621495 PMID:12640141 PMID:16987884 PMID:25741868 PMID:28492532 More... NCBI chr11:32,387,775...32,435,539
Ensembl chr11:32,387,775...32,435,564
JBrowse link
B-lymphoblastic leukemia/lymphoma MLL rearranged term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WT1 WT1 transcription factor IAGP ClinVar Annotator: match by term: Mixed phenotype acute leukemia with t(v;11q23.3) ClinVar PMID:25741868 NCBI chr11:32,387,775...32,435,539
Ensembl chr11:32,387,775...32,435,564
JBrowse link
B-lymphoblastic leukemia/lymphoma with BCR-ABL1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MSH6 mutS homolog 6 IAGP ClinVar Annotator: match by term: B Lymphoblastic Leukemia/Lymphoma with t(9;22)(q34.1;q11.2); BCR-ABL1 ClinVar PMID:22658618 PMID:25741868 PMID:28492532 NCBI chr 2:47,783,145...47,810,101
Ensembl chr 2:47,695,530...47,810,063
JBrowse link
B-lymphoblastic leukemia/lymphoma with ETV6-RUNX1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMPR1A bone morphogenetic protein receptor type 1A IAGP ClinVar Annotator: match by term: B Lymphoblastic Leukemia/Lymphoma with t(12;21)(p13.2;q22.1); ETV6-RUNX1 ClinVar PMID:25741868 PMID:28492532 PMID:30093976 NCBI chr10:86,755,763...86,932,844
Ensembl chr10:86,755,786...86,932,825
JBrowse link
G PALB2 partner and localizer of BRCA2 IAGP ClinVar Annotator: match by term: B Lymphoblastic Leukemia/Lymphoma with t(12;21)(p13.2;q22.1); ETV6-RUNX1 ClinVar PMID:25741868 PMID:28492532 PMID:33471991 NCBI chr16:23,603,165...23,641,310
Ensembl chr16:23,603,160...23,641,321
JBrowse link
G RB1 RB transcriptional corepressor 1 IAGP ClinVar Annotator: match by term: B Lymphoblastic Leukemia/Lymphoma with t(12;21)(p13.2;q22.1); ETV6-RUNX1 ClinVar PMID:25741868 PMID:28492532 NCBI chr13:48,303,751...48,481,890
Ensembl chr13:48,303,744...48,599,436
JBrowse link
G RECQL4 RecQ like helicase 4 IAGP ClinVar Annotator: match by term: B Lymphoblastic Leukemia/Lymphoma with t(12;21)(p13.2;q22.1); ETV6-RUNX1 ClinVar PMID:10678659 PMID:12734318 PMID:12838562 PMID:12952869 PMID:15897384 More... NCBI chr 8:144,511,288...144,517,833
Ensembl chr 8:144,511,288...144,517,845
JBrowse link
B-lymphoblastic leukemia/lymphoma with hyperdiploidy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CBL Cbl proto-oncogene IAGP ClinVar Annotator: match by term: B lymphoblastic leukemia lymphoma with hyperdiploidy ClinVar PMID:24033266 PMID:25741868 PMID:28492532 NCBI chr11:119,206,339...119,308,149
Ensembl chr11:119,206,298...119,313,926
JBrowse link
B-lymphoblastic leukemia/lymphoma with hypodiploidy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SDHA succinate dehydrogenase complex flavoprotein subunit A IAGP ClinVar Annotator: match by term: B-lymphoblastic leukemia/lymphoma with hypodiploidy ClinVar PMID:25741868 PMID:28492532 NCBI chr 5:218,320...268,746
Ensembl chr 5:218,303...257,082
JBrowse link
Burkitt lymphoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A4GALT alpha 1,4-galactosyltransferase (P1PK blood group) EXP CTD Direct Evidence: marker/mechanism CTD PMID:11482875 NCBI chr22:42,692,121...42,721,301
Ensembl chr22:42,692,121...42,721,298
JBrowse link
G ARID1A AT-rich interaction domain 1A EXP CTD Direct Evidence: marker/mechanism CTD PMID:23143597 NCBI chr 1:26,696,015...26,782,104
Ensembl chr 1:26,693,236...26,782,104
JBrowse link
G BBC3 BCL2 binding component 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18573879 NCBI chr19:47,220,824...47,232,860
Ensembl chr19:47,220,822...47,232,766
JBrowse link
G BCL2L2 BCL2 like 2 IEP mRNA:increased expression:lymph node RGD PMID:28094768 RGD:14394511 NCBI chr14:23,306,833...23,311,751
Ensembl chr14:23,298,790...23,311,751
JBrowse link
G BRCA1 BRCA1 DNA repair associated IAGP ClinVar Annotator: match by term: Burkitt lymphoma ClinVar PMID:17262179 PMID:25741868 PMID:26467025 PMID:28492532 PMID:31911673 More... NCBI chr17:43,044,295...43,170,327
Ensembl chr17:43,044,295...43,170,245
JBrowse link
G BTK Bruton tyrosine kinase treatment
ameliorates
HEP
IMP
mRNA:increased expression:multiple (human)
Human cell line in a mouse model
RGD PMID:28474336 PMID:30546948 RGD:124713565, RGD:124715474 NCBI chr  X:101,349,450...101,390,796
Ensembl chr  X:101,349,338...101,390,796
JBrowse link
G CALR calreticulin treatment IMP human cells and recombinant protein in a mouse model
human cell line and recombinant protein in a mouse model
RGD PMID:9858521 PMID:10961892 RGD:150521687, RGD:150521702 NCBI chr19:12,938,609...12,944,489
Ensembl chr19:12,938,578...12,944,489
JBrowse link
G CCT6B chaperonin containing TCP1 subunit 6B EXP CTD Direct Evidence: marker/mechanism CTD PMID:23143597 NCBI chr17:34,927,861...34,961,460
Ensembl chr17:34,927,859...34,981,078
JBrowse link
G CD40 CD40 molecule treatment IMP human cell line in a mouse model RGD PMID:9192773 RGD:11520790 NCBI chr20:46,118,314...46,129,858
Ensembl chr20:46,118,271...46,129,863
JBrowse link
G CD79B CD79b molecule treatment IMP human cells in mouse model RGD PMID:17374736 RGD:151665154 NCBI chr17:63,928,740...63,932,331
Ensembl chr17:63,928,738...63,932,336
JBrowse link
G FTCD formimidoyltransferase cyclodeaminase EXP CTD Direct Evidence: marker/mechanism CTD PMID:23143597 NCBI chr21:46,136,262...46,155,579
Ensembl chr21:46,136,160...46,155,579
JBrowse link
G GNA13 G protein subunit alpha 13 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23143597 NCBI chr17:65,009,289...65,056,740
Ensembl chr17:65,009,289...65,056,740
JBrowse link
G ID3 inhibitor of DNA binding 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23143595 PMID:23143597 NCBI chr 1:23,557,926...23,559,501
Ensembl chr 1:23,557,926...23,559,501
JBrowse link
G MIR21 microRNA 21 treatment IEP RGD PMID:27991481 RGD:41404643 NCBI chr17:59,841,266...59,841,337
Ensembl chr17:59,841,266...59,841,337
JBrowse link
G MIR23B microRNA 23b treatment IEP RGD PMID:27991481 RGD:41404643 NCBI chr 9:95,085,208...95,085,304
Ensembl chr 9:95,085,208...95,085,304
JBrowse link
G MLLT11 MLLT11 transcription factor 7 cofactor EXP CTD Direct Evidence: marker/mechanism CTD PMID:31587870 NCBI chr 1:151,060,397...151,069,544
Ensembl chr 1:151,060,397...151,069,544
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor IAGP
ISS
EXP
ClinVar Annotator: match by term: Burkitt lymphoma
OMIM:113970
CTD Direct Evidence: marker/mechanism
DNA:mutations:exons:multiple (human)
ClinVar
MouseDO
CTD
OMIM
RGD
PMID:8220424 PMID:25157968 PMID:27993330 PMID:8220424 PMID:8397370 RGD:1601453, RGD:10059619 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
JBrowse link
G PBX1 PBX homeobox 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:1967982 PMID:17244677 NCBI chr 1:164,559,184...164,886,047
Ensembl chr 1:164,555,584...164,899,296
JBrowse link
G PC pyruvate carboxylase EXP CTD Direct Evidence: marker/mechanism CTD PMID:23143597 NCBI chr11:66,848,420...66,958,383
Ensembl chr11:66,848,417...66,958,386
JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23143597 NCBI chr 5:68,215,756...68,301,821
Ensembl chr 5:68,215,740...68,301,821
JBrowse link
G RET ret proto-oncogene EXP CTD Direct Evidence: marker/mechanism CTD PMID:23143597 NCBI chr10:43,077,069...43,130,351
Ensembl chr10:43,077,064...43,130,351
JBrowse link
G SALL3 spalt like transcription factor 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23143597 NCBI chr18:78,979,818...78,998,969
Ensembl chr18:78,979,818...79,002,677
JBrowse link
G SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23143597 NCBI chr19:10,961,030...11,062,273
Ensembl chr19:10,960,932...11,079,426
JBrowse link
G TCF3 transcription factor 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:1967982 PMID:17244677 NCBI chr19:1,609,292...1,652,615
Ensembl chr19:1,609,291...1,652,615
JBrowse link
central nervous system lymphoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BTK Bruton tyrosine kinase ameliorates IMP RGD PMID:28552327 RGD:124715478 NCBI chr  X:101,349,450...101,390,796
Ensembl chr  X:101,349,338...101,390,796
JBrowse link
G CD79B CD79b molecule treatment IAGP RGD PMID:28619981 RGD:151665208 NCBI chr17:63,928,740...63,932,331
Ensembl chr17:63,928,738...63,932,336
JBrowse link
G IL10 interleukin 10 IAGP DNA:SNP:promoter:-1082G>A (human) RGD PMID:22628023 RGD:7364831 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor treatment IAGP RGD PMID:28619981 RGD:151665208 NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024
JBrowse link
childhood acute lymphocytic leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CTCF CCCTC-binding factor disease_progression IEP mRNA, protein:increased expression:bone marrow, blood (human) RGD PMID:24393203 RGD:151356757 NCBI chr16:67,562,526...67,639,185
Ensembl chr16:67,562,467...67,639,177
JBrowse link
chronic lymphocytic leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AK3 adenylate kinase 3 IEP protein:increased expression:peripheral blood mononuclear cell RGD PMID:27078856 RGD:13842476 NCBI chr 9:4,709,556...4,742,043
Ensembl chr 9:4,709,556...4,742,043
JBrowse link
G ARHGAP44 Rho GTPase activating protein 44 HEP mRNA:increased expression: (human) RGD PMID:36595475 RGD:401901275 NCBI chr17:12,789,498...12,991,643
Ensembl chr17:12,789,498...12,991,643
JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase IAGP ClinVar Annotator: match by term: Chronic lymphatic leukemia ClinVar PMID:12068308 PMID:12198537 PMID:12960123 PMID:14612909 PMID:14679157 More... NCBI chr 7:140,713,328...140,924,929
Ensembl chr 7:140,719,327...140,924,929
JBrowse link
G CD40LG CD40 ligand IEP protein:increased expression:serum (human) RGD PMID:9450802 RGD:11522717 NCBI chr  X:136,648,158...136,660,390
Ensembl chr  X:136,648,158...136,660,390
JBrowse link
G CD79B CD79b molecule IEP
IAGP
protein:decreased expression:peripheral blood cells (human)
mRNA, protein:splice variants, alternative forms:exon 3 (human)
protein:decreased expression:blood, B cell (human)
DNA:mutation:multiple (human)
protein:decreased expression:blood cells (human)
RGD PMID:10516749 PMID:10090943 PMID:10329919 PMID:10753858 PMID:10753858 RGD:151665125, RGD:151665190, RGD:11531139, RGD:151665152, RGD:151665152 NCBI chr17:63,928,740...63,932,331
Ensembl chr17:63,928,738...63,932,336
JBrowse link
G CD86 CD86 molecule IDA DNA:hypermethylation (human) RGD PMID:23154584 RGD:11354975 NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139
JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 IAGP ClinVar Annotator: match by term: Chronic lymphatic leukemia ClinVar PMID:25741868 PMID:26619011 NCBI chr 4:152,320,544...152,536,092
Ensembl chr 4:152,320,544...152,536,092
JBrowse link
G HRAS HRas proto-oncogene, GTPase IAGP ClinVar Annotator: match by term: Chronic lymphatic leukemia ClinVar PMID:12835555 PMID:16329078 PMID:16372351 PMID:16835863 PMID:17211612 More... NCBI chr11:532,242...535,576
Ensembl chr11:532,242...537,321
JBrowse link
G IL5 interleukin 5 IEP protein:increased expression:serum RGD PMID:21911837 RGD:11354912 NCBI chr 5:132,541,445...132,556,815
Ensembl chr 5:132,541,445...132,556,838
JBrowse link
G IRF4 interferon regulatory factor 4 disease_progression ISO
IAGP
DNA:SNPs:3' utr:multiple
DNA:SNP: :rs872071 (human)
DNA:missense mutation:exon:p.L116R (human)
RGD PMID:23897826 PMID:20123861 PMID:20731705 PMID:23926303 PMID:20090783 More... RGD:11526156, RGD:11530031, RGD:11530029, RGD:11530026, RGD:11530021, RGD:11526158 NCBI chr 6:391,752...411,443
Ensembl chr 6:391,739...411,443
JBrowse link
G KRAS KRAS proto-oncogene, GTPase IAGP ClinVar Annotator: match by term: Chronic lymphatic leukemia ClinVar PMID:2278970 PMID:3122217 PMID:12460918 PMID:15696205 PMID:16361624 More... NCBI chr12:25,205,246...25,250,929
Ensembl chr12:25,205,246...25,250,936
JBrowse link
G LRRC56 leucine rich repeat containing 56 IAGP ClinVar Annotator: match by term: Chronic lymphatic leukemia ClinVar PMID:12835555 PMID:16329078 PMID:16372351 PMID:16835863 PMID:17211612 More... NCBI chr11:506,462...554,912
Ensembl chr11:537,527...554,912
JBrowse link
G MIR155 microRNA 155 IEP miRNA:increased expression:peripheral blood mononuclear cell RGD PMID:29658610 RGD:21081544 NCBI chr21:25,573,980...25,574,044
Ensembl chr21:25,573,980...25,574,044
JBrowse link
G MIR21 microRNA 21 IEP miRNA:increased expression:peripheral blood mononuclear cell RGD PMID:29658610 RGD:21081544 NCBI chr17:59,841,266...59,841,337
Ensembl chr17:59,841,266...59,841,337
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor disease_progression IEP RGD PMID:20956327 RGD:11340590 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor IAGP ClinVar Annotator: match by term: Chronic lymphatic leukemia ClinVar PMID:21179087 PMID:22931316 PMID:23215570 PMID:23355535 PMID:26619011 More... NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024
JBrowse link
G NRAS NRAS proto-oncogene, GTPase IAGP ClinVar Annotator: match by term: Chronic lymphatic leukemia ClinVar PMID:1654209 PMID:2278970 PMID:2674680 PMID:3122217 PMID:6587382 More... NCBI chr 1:114,704,469...114,716,771
Ensembl chr 1:114,704,469...114,716,771
JBrowse link
G PON1 paraoxonase 1 susceptibility IAGP DNA:missense mutations:cds:p.L55M, p.Q192R (human) RGD PMID:26254371 RGD:11073982 NCBI chr 7:95,297,676...95,324,532
Ensembl chr 7:95,297,676...95,324,532
JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 IAGP ClinVar Annotator: match by term: Chronic lymphatic leukemia ClinVar PMID:12717436 PMID:14644997 PMID:15385933 PMID:15710330 PMID:15928039 More... NCBI chr12:112,418,947...112,509,918
Ensembl chr12:112,418,351...112,509,918
JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 susceptibility IAGP
IEP
DNA:snp:cds:p.R620W (rs2476601) (human)
protein:increased expression:B cell (human)
RGD PMID:23287625 PMID:22569400 RGD:11533998, RGD:11535006 NCBI chr 1:113,813,811...113,871,759
Ensembl chr 1:113,813,811...113,871,753
JBrowse link
G SF3B1 splicing factor 3b subunit 1 IAGP ClinVar Annotator: match by term: Chronic lymphatic leukemia ClinVar PMID:26619011 NCBI chr 2:197,389,784...197,435,093
Ensembl chr 2:197,388,515...197,435,079
JBrowse link
G SF3B2 splicing factor 3b subunit 2 IAGP ClinVar Annotator: match by term: Chronic lymphatic leukemia ClinVar PMID:26619011 NCBI chr11:66,052,364...66,069,308
Ensembl chr11:66,050,729...66,069,308
JBrowse link
G STAT3 signal transducer and activator of transcription 3 IEP protein:increased phosphorylation:peripheral blood mononuclear cell RGD PMID:29658610 RGD:21081544 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568
JBrowse link
G TP53 tumor protein p53 IAGP ClinVar Annotator: match by term: Chronic lymphatic leukemia ClinVar PMID:253702 PMID:1359493 PMID:1565143 PMID:1565144 PMID:1631137 More... NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546
JBrowse link
G XPO1 exportin 1 IAGP ClinVar Annotator: match by term: Chronic lymphatic leukemia ClinVar PMID:26619011 NCBI chr 2:61,477,849...61,538,612
Ensembl chr 2:61,476,032...61,538,741
JBrowse link
diffuse large B-cell lymphoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21325069 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) EXP CTD Direct Evidence: marker/mechanism CTD PMID:21625222 NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628
JBrowse link
G ALK ALK receptor tyrosine kinase EXP CTD Direct Evidence: marker/mechanism CTD PMID:22474449 NCBI chr 2:29,192,774...29,921,586
Ensembl chr 2:29,192,774...29,921,586
JBrowse link
G B2M beta-2-microglobulin EXP CTD Direct Evidence: marker/mechanism CTD PMID:7688627 NCBI chr15:44,711,517...44,718,145
Ensembl chr15:44,711,358...44,718,851
JBrowse link
G BCAS2 BCAS2 pre-mRNA processing factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:27356265 NCBI chr 1:114,567,557...114,581,615
Ensembl chr 1:114,567,557...114,581,629
JBrowse link
G BCL2 BCL2 apoptosis regulator EXP CTD Direct Evidence: marker/mechanism CTD PMID:16081686 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BCL2L2 BCL2 like 2 disease_progression IEP RGD PMID:28094768 RGD:14394511 NCBI chr14:23,306,833...23,311,751
Ensembl chr14:23,298,790...23,311,751
JBrowse link
G BCL6 BCL6 transcription repressor disease_progression IAGP
IEP
diffuse large B-cell lymphoma DNA:translocation:promoter,CDS:t(3;16)(q27;p11) results in IL21R promoter fused to BCL6 coding region RGD PMID:11821949 PMID:15701085 RGD:1600111, RGD:11530023 NCBI chr 3:187,721,377...187,745,468
Ensembl chr 3:187,721,377...187,745,725
JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase IAGP ClinVar Annotator: match by term: Diffuse large B cell lymphoma ClinVar NCBI chr 7:140,713,328...140,924,929
Ensembl chr 7:140,719,327...140,924,929
JBrowse link
G BRCA2 BRCA2 DNA repair associated IAGP ClinVar Annotator: match by term: Diffuse large B cell lymphoma ClinVar PMID:9150172 PMID:18489799 PMID:20104584 PMID:21138478 PMID:22798144 More... NCBI chr13:32,315,508...32,400,268
Ensembl chr13:32,315,086...32,400,268
JBrowse link
G BTK Bruton tyrosine kinase IAGP ClinVar Annotator: match by term: Diffuse large B cell lymphoma ClinVar PMID:24869598 PMID:25082755 PMID:25189416 PMID:25741868 PMID:27199251 More... NCBI chr  X:101,349,450...101,390,796
Ensembl chr  X:101,349,338...101,390,796
JBrowse link
G CARD11 caspase recruitment domain family member 11 IAGP
EXP
DNA:missense mutations:exons:multiple (human)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:25049379 PMID:26192916 PMID:18323416 RGD:11100036 NCBI chr 7:2,906,142...3,043,867
Ensembl chr 7:2,906,142...3,044,228
JBrowse link
G CAT catalase EXP CTD Direct Evidence: marker/mechanism CTD PMID:16081686 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CCDC86 coiled-coil domain containing 86 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23828858 NCBI chr11:60,842,113...60,851,081
Ensembl chr11:60,842,113...60,851,081
JBrowse link
G CD22 CD22 molecule treatment IMP RGD PMID:25708834 RGD:151665133 NCBI chr19:35,329,187...35,347,361
Ensembl chr19:35,319,261...35,347,361
JBrowse link
G CD40 CD40 molecule susceptibility IAGP DNA:SNP:5' utr:c.-1C>T (rs1883832) (human) RGD PMID:20473910 RGD:5490541 NCBI chr20:46,118,314...46,129,858
Ensembl chr20:46,118,271...46,129,863
JBrowse link
G CD79A CD79a molecule EXP CTD Direct Evidence: marker/mechanism CTD PMID:25049379 NCBI chr19:41,877,279...41,881,372
Ensembl chr19:41,877,279...41,881,372
JBrowse link
G CD79B CD79b molecule severity
treatment
EXP
IAGP
IMP
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Diffuse large B cell lymphoma
DNA:missense mutation:multiple, exon 5 (human)
DNA:missense mutation:multiple, exon 5-6 (human)
DNA:mutation:multiple (human)
CTD
ClinVar
RGD
PMID:11160144 PMID:21173233 PMID:31402495 PMID:31609782 PMID:25347427 More... RGD:151665203, RGD:11075852, RGD:151665133, RGD:151665120 NCBI chr17:63,928,740...63,932,331
Ensembl chr17:63,928,738...63,932,336
JBrowse link
G CDK1 cyclin dependent kinase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19223503 NCBI chr10:60,778,331...60,794,852
Ensembl chr10:60,778,331...60,794,852
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A EXP CTD Direct Evidence: marker/mechanism CTD PMID:21325069 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301
JBrowse link
G CHEK2 checkpoint kinase 2 IAGP ClinVar Annotator: match by term: Diffuse large B cell lymphoma ClinVar PMID:16199547 PMID:21876083 PMID:24713400 PMID:28492532 NCBI chr22:28,687,743...28,741,834
Ensembl chr22:28,687,743...28,742,422
JBrowse link
G CLTC clathrin heavy chain EXP CTD Direct Evidence: marker/mechanism CTD PMID:22474449 NCBI chr17:59,619,895...59,696,956
Ensembl chr17:59,619,680...59,696,956
JBrowse link
G CREBBP CREB binding protein IAGP ClinVar Annotator: match by term: Diffuse large B cell lymphoma ClinVar PMID:24755471 PMID:28481359 PMID:30239046 PMID:33323405 NCBI chr16:3,725,054...3,880,713
Ensembl chr16:3,725,054...3,880,713
JBrowse link
G DICER1 dicer 1, ribonuclease III disease_progression IEP RGD PMID:25195038 RGD:149735347 NCBI chr14:95,086,228...95,158,010
Ensembl chr14:95,086,228...95,158,010
JBrowse link
G DNMT3A DNA methyltransferase 3 alpha IAGP ClinVar Annotator: match by term: Diffuse large B cell lymphoma ClinVar PMID:25363760 PMID:25741868 PMID:29900417 PMID:30478443 PMID:32581362 More... NCBI chr 2:25,227,874...25,342,590
Ensembl chr 2:25,227,855...25,342,590
JBrowse link
G ETV6 ETS variant transcription factor 6 IAGP ClinVar Annotator: match by term: Diffuse large B cell lymphoma ClinVar PMID:35053500 NCBI chr12:11,649,674...11,895,377
Ensembl chr12:11,649,674...11,895,377
JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit EXP
IEP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:20081860 PMID:28438623 RGD:126779596 NCBI chr 7:148,807,383...148,884,291
Ensembl chr 7:148,807,257...148,884,321
JBrowse link
G FAS Fas cell surface death receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:26192916 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605
JBrowse link
G FCGR2A Fc gamma receptor IIa disease_progression IAGP DNA:SNP: :rs1801274 (human) RGD PMID:27282998 RGD:11344967 NCBI chr 1:161,505,457...161,524,048
Ensembl chr 1:161,505,430...161,524,013
JBrowse link
G FOXO1 forkhead box O1 IAGP ClinVar Annotator: match by term: Diffuse large B cell lymphoma ClinVar PMID:26314988 PMID:29721381 PMID:35079069 NCBI chr13:40,555,667...40,666,641
Ensembl chr13:40,555,667...40,666,641
JBrowse link
G GH-LCR growth hormone locus control region IAGP ClinVar Annotator: match by term: Diffuse large B cell lymphoma ClinVar PMID:11160144 PMID:31402495 NCBI chr17:63,917,193...63,958,852 JBrowse link
G GLI1 GLI family zinc finger 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21625222 NCBI chr12:57,459,785...57,472,268
Ensembl chr12:57,459,785...57,472,268
JBrowse link
G GSTM1 glutathione S-transferase mu 1 treatment IAGP RGD PMID:20303013 RGD:10450835 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039
JBrowse link
G GSTP1 glutathione S-transferase pi 1 susceptibility IAGP DNA:SNP: :(rs1695)(human) RGD PMID:19338043 RGD:8547939 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656
JBrowse link
G GSTT1 glutathione S-transferase theta 1 severity IAGP DNA:deletion:cds: RGD PMID:20303013 RGD:10450835
G ICAM1 intercellular adhesion molecule 1 disease_progression IEP proteion:increased expression:serum: RGD PMID:12598355 RGD:11354982 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
JBrowse link
G IL21R interleukin 21 receptor IAGP diffuse large B-cell lymphoma DNA:translocation:promoter,CDS:t(3;16)(q27;p11) results in IL21R promoter fused to BCL6 coding region RGD PMID:11821949 RGD:1600111 NCBI chr16:27,402,174...27,452,042
Ensembl chr16:27,402,174...27,452,042
JBrowse link
G IMMP2L inner mitochondrial membrane peptidase subunit 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27356265 NCBI chr 7:110,662,644...111,562,492
Ensembl chr 7:110,662,644...111,562,517
JBrowse link
G IRF4 interferon regulatory factor 4 disease_progression IEP RGD PMID:15701085 RGD:11530023 NCBI chr 6:391,752...411,443
Ensembl chr 6:391,739...411,443
JBrowse link
G KMT2D lysine methyltransferase 2D EXP CTD Direct Evidence: marker/mechanism CTD PMID:21804550 NCBI chr12:49,018,978...49,060,794
Ensembl chr12:49,018,975...49,060,794
JBrowse link
G MALT1 MALT1 paracaspase EXP CTD Direct Evidence: marker/mechanism CTD PMID:21173233 NCBI chr18:58,671,465...58,754,477
Ensembl chr18:58,671,465...58,754,477
JBrowse link
G MKI67 marker of proliferation Ki-67 disease_progression IEP RGD PMID:20919850 RGD:6483541 NCBI chr10:128,096,659...128,126,423
Ensembl chr10:128,096,659...128,126,423
JBrowse link
G MTHFR methylenetetrahydrofolate reductase susceptibility IAGP DNA:transition, transversion, haplotype:cds:g.677C>T, g.1298A>C (human) RGD PMID:17712558 RGD:6893517 NCBI chr 1:11,785,723...11,805,964
Ensembl chr 1:11,785,723...11,806,455
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:27356265 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor severity EXP
IAGP
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Diffuse large B cell lymphoma
DNA:missense mutation:L265P (human)
DNA:mutation:L265P, L265S (human)
CTD
ClinVar
RGD
PMID:21179087 PMID:22931316 PMID:23215570 PMID:23355535 PMID:25049379 More... RGD:151665203, RGD:11075852, RGD:151665120 NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024
JBrowse link
G NBN nibrin IAGP ClinVar Annotator: match by term: Diffuse large B cell lymphoma ClinVar PMID:9590180 PMID:16415040 PMID:28492532 NCBI chr 8:89,933,331...89,984,667
Ensembl chr 8:89,924,515...90,003,228
JBrowse link
G NECTIN2 nectin cell adhesion molecule 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27356265 NCBI chr19:44,846,297...44,889,223
Ensembl chr19:44,846,175...44,889,223
JBrowse link
G NF1 neurofibromin 1 IAGP ClinVar Annotator: match by term: Diffuse large B cell lymphoma ClinVar PMID:21390130 PMID:22158541 PMID:23292937 NCBI chr17:31,094,927...31,377,677
Ensembl chr17:31,094,927...31,382,116
JBrowse link
G NFKBIA NFKB inhibitor alpha no_association IAGP SNA:polymorphism(s) RGD PMID:15198731 RGD:2298905 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749
JBrowse link
G NOM1 nucleolar protein with MIF4G domain 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22474449 NCBI chr 7:156,949,712...156,973,176
Ensembl chr 7:156,949,712...156,973,176
JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21173233 NCBI chr16:2,538,021...2,603,188
Ensembl chr16:2,537,979...2,603,188
JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:21173233 NCBI chr 3:179,148,126...179,240,093
Ensembl chr 3:179,148,114...179,240,093
JBrowse link
G PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta EXP CTD Direct Evidence: marker/mechanism CTD PMID:21173233 NCBI chr 3:138,652,698...138,834,928
Ensembl chr 3:138,652,698...138,834,928
JBrowse link
G PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta EXP CTD Direct Evidence: marker/mechanism CTD PMID:21173233 NCBI chr 1:9,627,258...9,729,114
Ensembl chr 1:9,629,889...9,729,114
JBrowse link
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma EXP CTD Direct Evidence: marker/mechanism CTD PMID:21173233 NCBI chr 7:106,865,282...106,908,980
Ensembl chr 7:106,865,278...106,908,980
JBrowse link
G PMS2 PMS1 homolog 2, mismatch repair system component IAGP ClinVar Annotator: match by term: Diffuse large B cell lymphoma ClinVar NCBI chr 7:5,970,925...6,009,106
Ensembl chr 7:5,970,925...6,009,130
JBrowse link
G PRDM1 PR/SET domain 1 disease_progression IEP RGD PMID:22321048 RGD:150530470 NCBI chr 6:105,992,690...106,109,938
Ensembl chr 6:105,993,463...106,109,939
JBrowse link
G PRDX3 peroxiredoxin 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16081686 NCBI chr10:119,167,720...119,178,812
Ensembl chr10:119,167,720...119,178,812
JBrowse link
G PRDX4 peroxiredoxin 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16081686 NCBI chr  X:23,667,493...23,686,397
Ensembl chr  X:23,664,262...23,686,397
JBrowse link
G PRMT5 protein arginine methyltransferase 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:31123343 NCBI chr14:22,920,529...22,929,376
Ensembl chr14:22,920,525...22,929,408
JBrowse link
G PTEN phosphatase and tensin homolog IAGP ClinVar Annotator: match by term: Diffuse large B cell lymphoma ClinVar PMID:10468583 PMID:10555148 PMID:10698513 PMID:10866302 PMID:10866658 More... NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930
JBrowse link
G RANGAP1 Ran GTPase activating protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27150054 NCBI chr22:41,244,779...41,302,369
Ensembl chr22:41,244,779...41,286,187
JBrowse link
G RPS6KB1 ribosomal protein S6 kinase B1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19223503 NCBI chr17:59,893,121...59,950,574
Ensembl chr17:59,893,046...59,950,574
JBrowse link
G SEC31A SEC31 homolog A, COPII coat complex component EXP CTD Direct Evidence: marker/mechanism CTD PMID:22474449 NCBI chr 4:82,818,509...82,900,569
Ensembl chr 4:82,818,509...82,901,166
JBrowse link
G SF3A1 splicing factor 3a subunit 1 IAGP ClinVar Annotator: match by term: Diffuse large B cell lymphoma ClinVar PMID:22037554 PMID:26498691 PMID:33563892 NCBI chr22:30,331,988...30,356,894
Ensembl chr22:30,331,988...30,356,919
JBrowse link
G SKP2 S-phase kinase associated protein 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18850583 NCBI chr 5:36,152,111...36,193,530
Ensembl chr 5:36,151,989...36,196,849
JBrowse link
G SMURF2 SMAD specific E3 ubiquitin protein ligase 2 ISS MouseDO NCBI chr17:64,542,282...64,662,307
Ensembl chr17:64,542,282...64,662,307
JBrowse link
G SOCS1 suppressor of cytokine signaling 1 IAGP ClinVar Annotator: match by term: Diffuse large B cell lymphoma ClinVar PMID:19734449 PMID:23296022 PMID:26336985 PMID:28302137 PMID:29625055 NCBI chr16:11,254,417...11,256,204
Ensembl chr16:11,254,417...11,256,204
JBrowse link
G SOD2 superoxide dismutase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16081686 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
JBrowse link
G SOD3 superoxide dismutase 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16081686 NCBI chr 4:24,795,573...24,800,842
Ensembl chr 4:24,789,912...24,800,842
JBrowse link
G STAT3 signal transducer and activator of transcription 3 IAGP ClinVar Annotator: match by term: Diffuse large B cell lymphoma ClinVar PMID:21690253 PMID:22591296 PMID:22859607 PMID:23926297 PMID:25873174 More... NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568
JBrowse link
G SYK spleen associated tyrosine kinase EXP CTD Direct Evidence: marker/mechanism CTD PMID:33782605 NCBI chr 9:90,801,600...90,898,549
Ensembl chr 9:90,801,787...90,898,549
JBrowse link
G TBL1XR1 TBL1X/Y related 1 IAGP ClinVar Annotator: match by term: Diffuse large B cell lymphoma ClinVar PMID:9450851 PMID:16492805 PMID:21156281 PMID:21156282 PMID:25741868 More... NCBI chr 3:177,019,344...177,201,800
Ensembl chr 3:177,019,340...177,228,000
JBrowse link
G TP53 tumor protein p53 ISS
IAGP
ClinVar Annotator: match by term: Diffuse large B cell lymphoma MouseDO
ClinVar
PMID:1631137 PMID:1978757 PMID:8062826 PMID:8099841 PMID:8425176 More... NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546
JBrowse link
G TXNIP thioredoxin interacting protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:16081686 NCBI chr 1:145,992,435...145,996,579
Ensembl chr 1:145,992,435...145,996,579
JBrowse link
Enteropathy-Associated T-Cell Lymphoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SETD2 SET domain containing 2, histone lysine methyltransferase IAGP DNA:mutations:multiple (human) RGD PMID:27600764 RGD:150429643 NCBI chr 3:47,016,436...47,164,840
Ensembl chr 3:47,016,428...47,164,113
JBrowse link
G STAT5B signal transducer and activator of transcription 5B EXP CTD Direct Evidence: marker/mechanism CTD PMID:29200404 NCBI chr17:42,199,177...42,288,370
Ensembl chr17:42,199,176...42,288,633
JBrowse link
extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL10 BCL10 immune signaling adaptor IAGP ClinVar Annotator: match by term: MALT lymphoma ClinVar
OMIM
PMID:9989495 PMID:10380920 PMID:10408400 NCBI chr 1:85,265,776...85,276,632
Ensembl chr 1:85,265,776...85,276,632
JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 treatment IAGP DNA:gene fusion: (human) RGD PMID:21465313 RGD:153305955 NCBI chr11:102,317,484...102,339,403
Ensembl chr11:102,317,484...102,339,403
JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 IEP protein:increased expression: mucosa-associated lymphoid tissue (human) RGD PMID:27544389 RGD:152023632 NCBI chr 2:136,114,349...136,118,149
Ensembl chr 2:136,114,349...136,119,177
JBrowse link
G HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 treatment IAGP associated with Helicobacter Infections; DNA:polymorphim, haplotype: :HLA-DQA1*0103 (human) RGD PMID:16234023 RGD:5147794 NCBI chr 6:32,637,406...32,655,272
Ensembl chr 6:32,628,179...32,647,062
JBrowse link
follicular lymphoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP6AP1 ATPase H+ transporting accessory protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26691987 NCBI chr  X:154,428,677...154,436,516
Ensembl chr  X:154,428,633...154,436,516
JBrowse link
G ATP6V1B2 ATPase H+ transporting V1 subunit B2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26691987 NCBI chr 8:20,197,381...20,221,696
Ensembl chr 8:20,197,381...20,226,819
JBrowse link
G BCL10 BCL10 immune signaling adaptor IAGP ClinVar Annotator: match by term: Follicular lymphoma ClinVar PMID:9989495 NCBI chr 1:85,265,776...85,276,632
Ensembl chr 1:85,265,776...85,276,632
JBrowse link
G BCL2 BCL2 apoptosis regulator susceptibility IAGP
EXP
IEP
DNA:translocation: ;t(14;18)(q32;q21)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:3287162 PMID:12855623 PMID:16671111 PMID:3287162 RGD:1599473, RGD:734639 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G CD40 CD40 molecule susceptibility IAGP DNA:SNP:5' utr:c.-1C>T (rs1883832) (human) RGD PMID:20473910 RGD:5490541 NCBI chr20:46,118,314...46,129,858
Ensembl chr20:46,118,271...46,129,863
JBrowse link
G CD40LG CD40 ligand IMP human gene in a mouse model RGD PMID:25582824 RGD:11344981 NCBI chr  X:136,648,158...136,660,390
Ensembl chr  X:136,648,158...136,660,390
JBrowse link
G CD79B CD79b molecule treatment IMP human cells in mouse model RGD PMID:17374736 RGD:151665154 NCBI chr17:63,928,740...63,932,331
Ensembl chr17:63,928,738...63,932,336
JBrowse link
G CREBBP CREB binding protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:24362818 NCBI chr16:3,725,054...3,880,713
Ensembl chr16:3,725,054...3,880,713
JBrowse link
G EBF1 EBF transcription factor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24362818 NCBI chr 5:158,695,920...159,099,916
Ensembl chr 5:158,695,920...159,099,916
JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit EXP CTD Direct Evidence: marker/mechanism CTD PMID:24362818 NCBI chr 7:148,807,383...148,884,291
Ensembl chr 7:148,807,257...148,884,321
JBrowse link
G IFNA2 interferon alpha 2 EXP CTD Direct Evidence: therapeutic CTD PMID:12855623 NCBI chr 9:21,384,255...21,385,398
Ensembl chr 9:21,384,255...21,385,398
JBrowse link
G IRF4 interferon regulatory factor 4 severity IEP RGD PMID:17296585 RGD:11530032 NCBI chr 6:391,752...411,443
Ensembl chr 6:391,739...411,443
JBrowse link
G KDSR 3-ketodihydrosphingosine reductase IAGP
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:25526675 PMID:8417785 RGD:1598985 NCBI chr18:63,327,726...63,367,206
Ensembl chr18:63,327,726...63,367,228
JBrowse link
G KMT2D lysine methyltransferase 2D EXP CTD Direct Evidence: marker/mechanism CTD PMID:24362818 NCBI chr12:49,018,978...49,060,794
Ensembl chr12:49,018,975...49,060,794
JBrowse link
G MTHFR methylenetetrahydrofolate reductase EXP CTD Direct Evidence: marker/mechanism CTD PMID:16410450 NCBI chr 1:11,785,723...11,805,964
Ensembl chr 1:11,785,723...11,806,455
JBrowse link
G MTR 5-methyltetrahydrofolate-homocysteine methyltransferase EXP CTD Direct Evidence: marker/mechanism CTD PMID:16410450 NCBI chr 1:236,795,281...236,903,981
Ensembl chr 1:236,795,260...236,921,278
JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:24362818 NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024
JBrowse link
G RARRES1 retinoic acid receptor responder 1 ISS OMIM:151430 MouseDO NCBI chr 3:158,696,892...158,732,457
Ensembl chr 3:158,696,892...158,732,489
JBrowse link
G RRAGC Ras related GTP binding C EXP CTD Direct Evidence: marker/mechanism CTD PMID:26691987 NCBI chr 1:38,838,198...38,859,772
Ensembl chr 1:38,838,198...38,859,772
JBrowse link
G TNFAIP3 TNF alpha induced protein 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24362818 NCBI chr 6:137,866,349...137,883,312
Ensembl chr 6:137,867,214...137,883,314
JBrowse link
G TYMS thymidylate synthetase EXP CTD Direct Evidence: marker/mechanism CTD PMID:16410450 NCBI chr18:657,653...673,578
Ensembl chr18:657,653...673,578
JBrowse link
gastrointestinal lymphoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KMT2D lysine methyltransferase 2D disease_progression IEP RGD PMID:26722499 RGD:11553660 NCBI chr12:49,018,978...49,060,794
Ensembl chr12:49,018,975...49,060,794
JBrowse link
hairy cell leukemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GPX1 glutathione peroxidase 1 IDA RGD PMID:8843970 RGD:11353776 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605
JBrowse link
G IL1RN interleukin 1 receptor antagonist treatment IEP RGD PMID:9613675 RGD:11522762 NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016
JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24241536 NCBI chr15:66,386,912...66,491,544
Ensembl chr15:66,386,837...66,491,656
JBrowse link
G TNFSF8 TNF superfamily member 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:9058727 NCBI chr 9:114,893,343...114,930,595
Ensembl chr 9:114,893,343...114,930,595
JBrowse link
Hodgkin's lymphoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD40 CD40 molecule EXP CTD Direct Evidence: marker/mechanism CTD PMID:7621881 NCBI chr20:46,118,314...46,129,858
Ensembl chr20:46,118,271...46,129,863
JBrowse link
G CD40LG CD40 ligand EXP CTD Direct Evidence: marker/mechanism CTD PMID:7621881 PMID:8656679 NCBI chr  X:136,648,158...136,660,390
Ensembl chr  X:136,648,158...136,660,390
JBrowse link
G CD68 CD68 molecule severity IEP associated with Epstein-Barr Virus Infections;protein:increased expression:tumor(human)
protein:increased expression:tumor (human)
RGD PMID:21071500 PMID:23045593 RGD:40925944, RGD:40925946 NCBI chr17:7,579,638...7,582,111
Ensembl chr17:7,579,491...7,582,111
JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator EXP CTD Direct Evidence: marker/mechanism CTD PMID:17659339 NCBI chr 2:201,116,164...201,176,687
Ensembl chr 2:201,116,154...201,176,687
JBrowse link
G CSF3 colony stimulating factor 3 EXP CTD Direct Evidence: therapeutic CTD PMID:17562247 NCBI chr17:40,015,440...40,017,813
Ensembl chr17:40,015,361...40,017,813
JBrowse link
G FGFR3 fibroblast growth factor receptor 3 IAGP ClinVar Annotator: match by term: Classic Hodgkin lymphoma ClinVar PMID:28492532 PMID:32934698 NCBI chr 4:1,793,293...1,808,867
Ensembl chr 4:1,793,293...1,808,872
JBrowse link
G FGFR4 fibroblast growth factor receptor 4 IAGP ClinVar Annotator: match by term: Classic Hodgkin lymphoma ClinVar PMID:25741868 PMID:32934698 NCBI chr 5:177,086,915...177,098,144
Ensembl chr 5:177,086,905...177,098,144
JBrowse link
G GATA3 GATA binding protein 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21037568 NCBI chr10:8,045,333...8,075,198
Ensembl chr10:8,045,378...8,075,198
JBrowse link
G GSTM1 glutathione S-transferase mu 1 disease_progression IAGP RGD PMID:21916526 RGD:10450802 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039
JBrowse link
G GSTP1 glutathione S-transferase pi 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:11406608 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656
JBrowse link
G GSTT1 glutathione S-transferase theta 1 disease_progression IAGP RGD PMID:21916526 RGD:10450802
G ICAM1 intercellular adhesion molecule 1 IEP
EXP
protein:increased expression:serum:
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:7621881 PMID:8656679 PMID:7686390 RGD:11520780 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
JBrowse link
G IFNA2 interferon alpha 2 EXP CTD Direct Evidence: therapeutic CTD PMID:16170182 NCBI chr 9:21,384,255...21,385,398
Ensembl chr 9:21,384,255...21,385,398
JBrowse link
G IL10 interleukin 10 treatment IEP RGD PMID:21466366 RGD:11049168 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G IL6 interleukin 6 treatment IAGP
IEP
DNA:SNPs: :multiple RGD PMID:19573080 PMID:21466366 RGD:11049165, RGD:11049168 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit IEP RGD PMID:12145210 RGD:1549449 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048