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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:ovarian serous carcinoma
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Accession:DOID:0050933 term browser browse the term
Definition:An ovarian carcinoma that has_material_basis_in the lining of the ovary and produces a serum-like fluid. (DO)
Synonyms:exact_synonym: serous carcinoma of ovary
 xref: EFO:0002917;   EFO:1001516;   MONDO:0005211


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ovarian serous carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgef10l Rho guanine nucleotide exchange factor 10 like susceptibility ISO DNA:SNP:intron:rs10788679(human) RGD PMID:29979793 RGD:14348955 NCBI chr 5:152,792,247...152,935,255
Ensembl chr 5:152,792,252...152,919,538 		JBrowse link
G Ccng1 cyclin G1 severity ISO mRNA, protein:increased expression:ovary (human) RGD PMID:30565428 RGD:151361205 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641 		JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 ISO ovarian serous carcinoma RGD PMID:16627982 RGD:2293332 NCBI chr10:50,842,348...50,947,063
Ensembl chr10:50,344,915...50,447,993 		JBrowse link
G Ncam1 neural cell adhesion molecule 1 disease_progression ISO RGD PMID:25455994 RGD:40907066 NCBI chr 8:49,865,629...50,165,687
Ensembl chr 8:49,865,633...50,166,014 		JBrowse link
G Pten phosphatase and tensin homolog exacerbates ISO protein:increased expression:ovary, peritoneum (human) RGD PMID:26166715 RGD:11532228 NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Wt1 WT1 transcription factor ISO RGD PMID:19856421 RGD:2315539 NCBI chr 3:112,019,721...112,068,454
Ensembl chr 3:91,567,001...91,613,643 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19143
    disease of cellular proliferation 7895
      cancer 5723
        cell type cancer 3784
          carcinoma 3272
            ovarian carcinoma 95
              ovarian serous carcinoma 6
Path 2
Term Annotations click to browse term
  disease 19143
    disease of anatomical entity 18456
      Urogenital Diseases 5402
        Female Urogenital Diseases and Pregnancy Complications 2679
          Female Urogenital Diseases 2195
            female reproductive system disease 2192
              Adnexal Diseases 1080
                ovarian disease 1071
                  Ovarian Neoplasms 757
                    ovarian cancer 638
                      ovary epithelial cancer 120
                        malignant ovarian surface epithelial-stromal neoplasm 95
                          ovarian carcinoma 95
                            ovarian serous carcinoma 6
paths to the root