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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:splenic marginal zone lymphoma
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Accession:DOID:0050750 term browser browse the term
Definition:A marginal zone B-cell lymphocyte located_in the spleen comprised of B-cells in place of white pulp. (DO)
Synonyms:exact_synonym: splenic lymphoma with villous lymphocytes;   splenic marginal zone B-cell lymphoma
 xref: EFO:1000550;   NCI:C4663


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splenic marginal zone lymphoma term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd79b CD79b molecule ISO protein:decreased expression:blood, B cell (human) RGD PMID:10329919 RGD:11531139 NCBI chr10:91,239,354...91,242,500
Ensembl chr10:91,239,356...91,242,625 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19050
    disease of cellular proliferation 7793
      Neoplasms by Site 7249
        Splenic Neoplasms 3
          spleen cancer 2
            splenic marginal zone lymphoma 1
Path 2
Term Annotations click to browse term
  disease 19050
    disease of anatomical entity 18384
      Immune & Inflammatory Diseases 5742
        immune system disease 4930
          lymphatic system disease 1749
            lymphatic system cancer 669
              lymphoma 581
                non-Hodgkin lymphoma 490
                  B-cell lymphoma 348
                    marginal zone lymphoma 8
                      splenic marginal zone lymphoma 1
paths to the root