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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:marginal zone lymphoma
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Accession:DOID:0050748 term browser browse the term
Definition:A B-cell lymphoma arising from the marginal zone of lymphoid tissues that is characterized by the presence of small to medium sized atypical lymphocytes. (DO)
Synonyms:exact_synonym: marginal zone B-cell lymphoma
 primary_id: MESH:D018442
 xref: EFO:1000630


show annotations for term's descendants           Sort by:
marginal zone lymphoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl10 BCL10, immune signaling adaptor ISO CTD Direct Evidence: marker/mechanism CTD NCBI chr 2:237,501,181...237,510,821
Ensembl chr 2:237,501,134...237,511,829 		JBrowse link
G Gfi1 growth factor independent 1 transcriptional repressor disease_progression ISO RGD PMID:15231650 RGD:1581305 NCBI chr14:2,185,489...2,204,191
Ensembl chr14:2,187,286...2,196,730 		JBrowse link
G RT1-Ba RT1 class II, locus Ba ISO associated with Helicobacter Infections;DNA:polymorphism: :HLA-DQA1*0103 (human) RGD PMID:16234023 RGD:5147794 NCBI chr20:4,577,057...4,581,650
Ensembl chr20:4,576,843...4,581,653 		JBrowse link
G RT1-Bb RT1 class II, locus Bb ISO associated with Helicobacter Infections;DNA:polymorphism: :HLA-DQB1*0601 (human) RGD PMID:16234023 RGD:5147794 NCBI chr20:4,598,475...4,604,118
Ensembl chr20:4,598,475...4,604,118 		JBrowse link
G Tp53 tumor protein p53 ISO GAD PMID:15118671 RGD:1331525 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl10 BCL10, immune signaling adaptor ISO ClinVar Annotator: match by term: MALT lymphoma ClinVar
OMIM		 PMID:9989495 PMID:10380920 PMID:10408400 NCBI chr 2:237,501,181...237,510,821
Ensembl chr 2:237,501,134...237,511,829 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 treatment ISO DNA:gene fusion: (human) RGD PMID:21465313 RGD:153305955 NCBI chr 8:13,285,702...13,313,329
Ensembl chr 8:13,285,703...13,298,590 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 ISO protein:increased expression: mucosa-associated lymphoid tissue (human) RGD PMID:27544389 RGD:152023632 NCBI chr13:42,630,383...42,634,288
Ensembl chr13:42,630,104...42,634,459 		JBrowse link
G RT1-Ba RT1 class II, locus Ba treatment ISO associated with Helicobacter Infections; DNA:polymorphim, haplotype: :HLA-DQA1*0103 (human) RGD PMID:16234023 RGD:5147794 NCBI chr20:4,577,057...4,581,650
Ensembl chr20:4,576,843...4,581,653 		JBrowse link
splenic marginal zone lymphoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd79b CD79b molecule ISO protein:decreased expression:blood, B cell (human) RGD PMID:10329919 RGD:11531139 NCBI chr10:91,739,134...91,742,312
Ensembl chr10:91,739,137...91,742,405 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14566
    disease of anatomical entity 13676
      hematopoietic system disease 1590
        leukocyte disease 580
          B-cell lymphoma 339
            marginal zone lymphoma 8
              extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue + 4
              nodal marginal zone lymphoma 0
              splenic marginal zone lymphoma 1
Path 2
Term Annotations click to browse term
  disease 14566
    disease of cellular proliferation 5586
      cancer 4230
        organ system cancer 3954
          immune system cancer 659
            lymphatic system cancer 659
              lymphoma 574
                non-Hodgkin lymphoma 482
                  B-cell lymphoma 339
                    marginal zone lymphoma 8
                      extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue + 4
                      nodal marginal zone lymphoma 0
                      splenic marginal zone lymphoma 1
paths to the root