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CLINICAL MEASUREMENT - ANNOTATIONS

The Clinical Measurement Ontology (CMO), Measurement Methods Ontology (MMO), and Experimental Condition Ontology (XCO) are currently being developed at the Rat Genome Database. For more information about these vocabularies please see Shimoyama et al. Three ontologies to define phenotype measurement data. Front Genet. 2012;3:87. Epub 2012 May 28 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:logarithm of the concentration of norepinephrine at which the force of blood vessel contraction is half the maximum value
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Accession:CMO:0003677 term browser browse the term
Definition:A calculated value for logarithm of the concentration of norepinephrine at which the energy produced by the active reduction in the diameter of a blood vessel in response to the application of norepinephrine is halfway between the baseline value and the highest achievable value of such norepinephrine-induced contractile energy. The logarithm of the concentration is the exponent indicating the power to which 10 must be raised to obtain that concentration value.
Synonyms:exact_synonym: logarithm of the concentration of noradrenaline at which the force of blood vessel contraction is half the maximum value;   noradrenaline -pEC50;   noradrenaline Log EC50
 xref: CHEBI:33569;   PMID:23868088


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Path 1
Term Annotations click to browse term
  clinical measurement 0
    chemical response/sensitivity measurement 0
      norepinephrine response/sensitivity measurement 0
        logarithm of the concentration of norepinephrine at which the force of blood vessel contraction is half the maximum value 0
Path 2
Term Annotations click to browse term
  clinical measurement 0
    cardiovascular measurement 0
      blood vessel measurement 0
        blood vessel constriction measurement 0
          blood vessel contractile force measurement 0
            calculated blood vessel contractile force measurement 0
              logarithm of the concentration of vasoconstrictor at which the force of blood vessel contraction is half the maximum value (Log EC50) 0
                logarithm of the concentration of norepinephrine at which the force of blood vessel contraction is half the maximum value 0
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