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CLINICAL MEASUREMENT - ANNOTATIONS

The Clinical Measurement Ontology (CMO), Measurement Methods Ontology (MMO), and Experimental Condition Ontology (XCO) are currently being developed at the Rat Genome Database. For more information about these vocabularies please see Shimoyama et al. Three ontologies to define phenotype measurement data. Front Genet. 2012;3:87. Epub 2012 May 28 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:CD11b/c+ splenocyte count
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Accession:CMO:0003534 term browser browse the term
Definition:The number of splenocytes expressing CD11B and/or CD11C molecules on their surface in a specified sample of spleen tissue. The CD11B molecule (ITGAM, integrin alpha M chain) combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 (Mac-1), or inactivated-C3b (iC3b) receptor 3 (CR3). The CD11C molecule (ITGAX, integrin subunit alpha X chain) combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4).


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Related Phenotype Data for Term "CD11b/c+ splenocyte count" (CMO:0003534)

Rat Strains:
Clinical Measurements:
Experimental Conditions:
Measurement Methods:
Term paths to the root
Path 1
Term Annotations click to browse term
  clinical measurement 2369
    cell measurement 24
      mononuclear cell measurement 7
        mononuclear cell count 7
          spleen mononuclear cell count 3
            CD11b/c+ splenocyte count 0
Path 2
Term Annotations click to browse term
  clinical measurement 2369
    cell measurement 24
      immune cell measurement 16
        white blood cell measurement 15
          white blood cell count 15
            mononuclear cell count 7
              spleen mononuclear cell count 3
                CD11b/c+ splenocyte count 0
paths to the root