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CLINICAL MEASUREMENT - ANNOTATIONS

The Clinical Measurement Ontology (CMO), Measurement Methods Ontology (MMO), and Experimental Condition Ontology (XCO) are currently being developed at the Rat Genome Database. For more information about these vocabularies please see Shimoyama et al. Three ontologies to define phenotype measurement data. Front Genet. 2012;3:87. Epub 2012 May 28 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:concentration of potassium chloride at which the force of blood vessel contraction is half the maximum value (EC50)
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Accession:CMO:0002462 term browser browse the term
Definition:A calculated value for the concentration of potassium chloride (KCl) at which the energy produced by the active reduction in the diameter of a blood vessel in response to the application of KCl is halfway between the baseline value and the highest achievable value of such KCl-induced contractile energy. Potassium chloride is the salt of the potassium cation (K+) and the chlorine/chloride anion (Cl-). It is used as an eletroylyte replenisher and has mild vasoconstrictive properties when applied directly to blood vessels.
Synonyms:exact_synonym: potassium chloride half maximal effective concentration (EC50)
 related_synonym: KCl half maximal effective concentration (EC50)
 xref: CHEBI:32588


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Path 1
Term Annotations click to browse term
  clinical measurement 2369
    chemical response/sensitivity measurement 0
      potassium chloride response/sensitivity measurement 0
        concentration of potassium chloride at which the force of blood vessel contraction is half the maximum value (EC50) 0
Path 2
Term Annotations click to browse term
  clinical measurement 2369
    cardiovascular measurement 610
      blood vessel measurement 44
        blood vessel constriction measurement 0
          blood vessel contractile force measurement 0
            calculated blood vessel contractile force measurement 0
              concentration of vasoconstrictor at which the force of blood vessel contraction is half the maximum value (EC50) 0
                concentration of potassium chloride at which the force of blood vessel contraction is half the maximum value (EC50) 0
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