The Clinical Measurement Ontology (CMO), Measurement Methods Ontology (MMO), and Experimental Condition Ontology (XCO) are currently being developed at the Rat Genome Database. For more information about these vocabularies please see Shimoyama et al. Three ontologies to define phenotype measurement data. Front Genet. 2012;3:87. Epub 2012 May 28 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Measurement of the number of lymphocytes in a specified sample of blood which express both the surface CD45RC antigen and surface CD4 antigen. D45RC, also known as the leukocyte common antigen, is the protein produced by the PTPRC (protein tyrosine phosphatase, receptor type, C) gene and has been shown to be an essential regulator of T- and B-cell antigen receptor signaling.
Synonyms:
related_synonym:
blood CD45RC(+) CD4(+) T cell count; blood CD45RC+ CD4+ T cell count; blood LCA T4 T cell count