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CLINICAL MEASUREMENT - ANNOTATIONS

The Clinical Measurement Ontology (CMO), Measurement Methods Ontology (MMO), and Experimental Condition Ontology (XCO) are currently being developed at the Rat Genome Database. For more information about these vocabularies please see Shimoyama et al. Three ontologies to define phenotype measurement data. Front Genet. 2012;3:87. Epub 2012 May 28 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:spinal cord Cd74 protein level
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Accession:CMO:0002131 term browser browse the term
Definition:The amount in a specified sample of spinal cord of Cd74, a cell surface protein which associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for the immune response. Cd74 also serves as the cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) for initiation of survival pathways and cell proliferation.


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spinal cord Cd74 protein level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
Q Neuinf5 Neuroinflammation QTL 5 IDA RGD PMID:19525015 RGD:2311085 NCBI chr 7:9,462,246...58,265,113 JBrowse link
Term paths to the root
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Term Annotations click to browse term
  clinical measurement 2369
    tissue composition measurement 26
      tissue molecular composition measurement 26
        spinal cord molecular composition measurement 11
          spinal cord protein/peptide composition measurement 6
            spinal cord Cd74 protein level 1
Path 2
Term Annotations click to browse term
  clinical measurement 2369
    nervous system measurement 63
      central nervous system measurement 29
        spinal cord measurement 11
          spinal cord morphological measurement 11
            spinal cord molecular composition measurement 11
              spinal cord protein/peptide composition measurement 6
                spinal cord Cd74 protein level 1
paths to the root