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CLINICAL MEASUREMENT - ANNOTATIONS

The Clinical Measurement Ontology (CMO), Measurement Methods Ontology (MMO), and Experimental Condition Ontology (XCO) are currently being developed at the Rat Genome Database. For more information about these vocabularies please see Shimoyama et al. Three ontologies to define phenotype measurement data. Front Genet. 2012;3:87. Epub 2012 May 28 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:serum immunoglobulin G2a level
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Accession:CMO:0002116 term browser browse the term
Definition:The amount in a specified sample of serum of the G2a subclass of immunoglobulin G (IgG), the most abundant class of antibodies found in blood serum and lymph. IgG antibodies are active against bacteria, fungi, viruses, and foreign particles, and trigger action of the complement system. IgG subclasses differ in the structure of their hinge regions. IgG2a is able to activate complement and bind to the Fc receptor on phagocytic cells.
Synonyms:exact_synonym: serum IgG2a level


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serum immunoglobulin G2a level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
Q Pia39 Pristane induced arthritis QTL 39 IDA RGD PMID:14674011 RGD:2302026 NCBI chr14:8,267,090...53,267,090 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  clinical measurement 2369
    immune system measurement 49
      immunoglobulin measurement 21
        blood immunoglobulin measurement 21
          blood immunoglobulin G level 9
            serum immunoglobulin G level 9
              serum immunoglobulin G subclass level 6
                serum immunoglobulin G2a level 1
Path 2
Term Annotations click to browse term
  clinical measurement 2369
    blood measurement 443
      blood chemistry measurement 426
        blood protein measurement 188
          blood globulin measurement 21
            blood immunoglobulin measurement 21
              serum immunoglobulin measurement 21
                serum immunoglobulin G level 9
                  serum immunoglobulin G subclass level 6
                    serum immunoglobulin G2a level 1
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