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CLINICAL MEASUREMENT - ANNOTATIONS

The Clinical Measurement Ontology (CMO), Measurement Methods Ontology (MMO), and Experimental Condition Ontology (XCO) are currently being developed at the Rat Genome Database. For more information about these vocabularies please see Shimoyama et al. Three ontologies to define phenotype measurement data. Front Genet. 2012;3:87. Epub 2012 May 28 or contact us (http://rgd.mcw.edu/contact/index.shtml).

Term:blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio
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Accession:CMO:0001990 term browser browse the term
Definition:A calculated measurement in which the number of lymphocytes expressing both a relatively high amount of surface CD45RC antigen and surface CD8 antigen is divided by the number of lymphocytes expressing both a relatively low amount of surface CD45RC antigen and surface CD8 antigen, and presented as a ratio, fraction, quotient or percentage. CD45RC, also known as the leukocyte common antigen, is the protein produced by the PTPRC (protein tyrosine phosphatase, receptor type, C) gene and has been shown to be an essential regulator of T- and B-cell antigen receptor signaling.
Synonyms:exact_synonym: blood CD45RChigh CD8 T cell count to CD45RClow CD8 T cell count ratio



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blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
Q Cdexp1 CD45RC expression in CD8 T cells QTL 1 IDA RGD PMID:15322174 RGD:1302824 NCBI chr 9:1,024,537...67,509,080 JBrowse link
Q Cdexp2 CD45RC expression in CD8 T cells QTL 2 IDA RGD PMID:15322174 RGD:1302824 NCBI chr20:3,621,649...10,078,919 JBrowse link

Related Phenotype Data for Term "blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio" (CMO:0001990)

Rat Strains:
Clinical Measurements:
Experimental Conditions:
Measurement Methods:

Term paths to the root
Path 1
Term Annotations click to browse term
  clinical measurement 2369
    cell measurement 24
      mononuclear cell measurement 7
        mononuclear cell count 7
          blood mononuclear cell count 3
            blood lymphocyte count 3
              blood T lymphocyte count 3
                blood CD8 cell count 2
                  calculated blood CD8 cell count 2
                    blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio 2
Path 2
Term Annotations click to browse term
  clinical measurement 2369
    immune system measurement 49
      immune cell measurement 16
        immune cell count 15
          white blood cell count 11
            blood differential white blood cell count 6
              blood mononuclear cell count 3
                blood lymphocyte count 3
                  blood T lymphocyte count 3
                    blood CD8 cell count 2
                      calculated blood CD8 cell count 2
                        blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio 2
paths to the root