The Clinical Measurement Ontology (CMO), Measurement Methods Ontology (MMO), and Experimental Condition Ontology (XCO) are currently being developed at the Rat Genome Database. For more information about these vocabularies please see Shimoyama et al. Three ontologies to define phenotype measurement data. Front Genet. 2012;3:87. Epub 2012 May 28 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:
percentage of study population developing chronic experimental autoimmune encephalomyelitis during a period of time
The number of new cases of chronic experimental autoimmune encephalomyelitis (EAE) appearing in a study population during a certain period compared to the total number of individuals in the study population, expressed as a percentage. EAE is an animal model of brain inflammation in which inflammation is induced through immunization of the animal with central nervous system antigens or by the passive transfer of autoreactive T cells. Chronic EAE is a variant of EAE characterized by a long duration and slow, constant progression.
Comment:
For disease characterized by repeated symptomatic attacks followed by complete or almost complete improvement, use the term for relapsing-remitting experimental autoimmune encephalomyelitis.
Synonyms:
related_synonym:
chronic EAE incidence; percentage of study population developing chronic EAE during a period of time