The Clinical Measurement Ontology (CMO), Measurement Methods Ontology (MMO), and Experimental Condition Ontology (XCO) are currently being developed at the Rat Genome Database. For more information about these vocabularies please see Shimoyama et al. Three ontologies to define phenotype measurement data. Front Genet. 2012;3:87. Epub 2012 May 28 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:
percentage of study population displaying chronic experimental autoimmune encephalomyelitis at a point in time
A measurement in which the number of individuals in a study population that display, i.e., are manifesting symptoms of or have been diagnosed with, chronic experimental autoimmune encephalomyelitis (EAE) at a point in time are compared to the total number of individuals in the study population. Often expressed as a percentage but could be expressed as a ratio. EAE is an animal model of brain inflammation in which inflammation is induced through immunization of the animal with central nervous system antigens or by the passive transfer of autoreactive T cells. Chronic EAE is a variant of EAE characterized by a long duration and slow, constant progression.
Comment:
For disease characterized by repeated symptomatic attacks followed by complete or almost complete improvement, use the term for relapsing-remitting experimental autoimmune encephalomyelitis.
Synonyms:
related_synonym:
chronic EAE prevalence; percentage of study population displaying chronic EAE at a point in time