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CLINICAL MEASUREMENT - ANNOTATIONS

The Clinical Measurement Ontology (CMO), Measurement Methods Ontology (MMO), and Experimental Condition Ontology (XCO) are currently being developed at the Rat Genome Database. For more information about these vocabularies please see Shimoyama et al. Three ontologies to define phenotype measurement data. Front Genet. 2012;3:87. Epub 2012 May 28 or contact us (http://rgd.mcw.edu/contact/index.shtml).

Term:antibody titer
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Accession:CMO:0001862 term browser browse the term
Definition:Measurement of the amount of a specific antibody determined as the maximal dilution of the antibody solution at which that antibody can still be detected. The value represents the denominator of the dilution ratio, i.e., a titer of 32 means that the sample can be maximally diluted 1/32 and still contain enough antibody to be detected. An antibody is an immunoglobulin molecule possessing a specific amino acid sequence that binds to a specific antigen, a substance introduced into an organism which initiates an immune response including the production of the very antibodies which bind to it in an effort to destroy it.



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calculated serum anti-rat type 2 collagen autoantibody titer term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
Q Ciaa1 CIA Autoantibody QTL 1 IDA RGD PMID:11001927 RGD:61067 NCBI chr20:2,646,395...4,597,031 JBrowse link
Q Ciaa4 CIA Autoantibody QTL 4 IDA RGD PMID:11001927 RGD:61067 NCBI chr 4:126,395,976...167,139,601 JBrowse link
Q Ciaa5 CIA Autoantibody QTL 5 IDA RGD PMID:11001927 RGD:61067 NCBI chr 5:94,858,972...143,070,159 JBrowse link
calculated serum anti-type 2 collagen antibody titer term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
Q Ciaa2 CIA Autoantibody QTL 2 IDA RGD PMID:10857786 RGD:61066 NCBI chr10:63,221,094...107,211,142 JBrowse link
Q Ciaa3 CIA Autoantibody QTL 3 IDA RGD PMID:10857786 RGD:61066 NCBI chr 9:7,954,720...22,071,169 JBrowse link

Term paths to the root
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Term Annotations click to browse term
  clinical measurement 2369
    immune system measurement 49
      immunoglobulin measurement 21
        antibody measurement 12
          antibody titer 5
            autoantibody titer + 3
            blood antibody titer + 5
            change in antibody titer + 0
paths to the root