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CLINICAL MEASUREMENT - ANNOTATIONS

The Clinical Measurement Ontology (CMO), Measurement Methods Ontology (MMO), and Experimental Condition Ontology (XCO) are currently being developed at the Rat Genome Database. For more information about these vocabularies please see Shimoyama et al. Three ontologies to define phenotype measurement data. Front Genet. 2012;3:87. Epub 2012 May 28 or contact us (http://rgd.mcw.edu/contact/index.shtml).

Term:blood high density lipoprotein cholesterol level
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Accession:CMO:0000052 term browser browse the term
Definition:Measurement of the amount of cholesterol, a eukaryotic sterol that in higher animals is the precursor of bile acids and steroid hormones and a key constituent of cell membranes, carried in high-density lipoprotein (HDL) molecules in a specified volume of blood, the fluid that circulates through the heart, arteries, capillaries and veins carrying nutrients and oxygen to the body tissues and metabolites away from them. HDL is the smallest of the major lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The HDL class of lipoproteins, specifically the subtypes of HDL2 and HDL3, have densities between 1.063 and 1.210 g/ml.
Comment:Values for density ranges of the lipoprotein classes are approximate. The classes may be defined differently by different researchers, in part because class definitions depend on the number of subclasses into which the lipoprotein fractions are divided.
Synonyms:exact_synonym: blood HDL-C
 related_synonym: blood HDL level



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blood high density lipoprotein cholesterol level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
Q Scl32 Serum cholesterol level QTL 32 IDA RGD PMID:15452030 RGD:1302893 NCBI chr17:15,781,592...60,781,592 JBrowse link
Q Scl76 Serum cholesterol level QTL 76 IDA RGD PMID:25296178 RGD:10402111 NCBI chr 4:49,178,116...57,114,705 JBrowse link
Q Scl77 Serum cholesterol level QTL 77 IDA RGD PMID:25296178 RGD:10402111 NCBI chr 4:49,178,116...57,114,705 JBrowse link
serum high density lipoprotein cholesterol level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
Q Scl12 Serum cholesterol level QTL 12 IDA RGD PMID:8698878 RGD:61079 NCBI chr19:13,926,401...30,303,727 JBrowse link
Q Scl27 Serum cholesterol level QTL 27 IDA RGD PMID:11721057 RGD:70849 NCBI chr18:52,292,875...59,796,643 JBrowse link
Q Scl28 Serum cholesterol level QTL 28 IDA RGD PMID:11721057 RGD:70849 NCBI chr18:11,944,299...24,797,117 JBrowse link
Q Scl61 Serum cholesterol level QTL 61 IDA RGD PMID:10720472 RGD:619689 NCBI chr17:27,389,946...53,481,766 JBrowse link

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  clinical measurement 2369
    blood measurement 439
      blood chemistry measurement 426
        blood protein measurement 188
          blood lipoprotein measurement 70
            blood lipoprotein level 70
              blood lipoprotein cholesterol level 19
                blood high density lipoprotein cholesterol level 7
                  plasma high density lipoprotein cholesterol level 0
                  serum high density lipoprotein cholesterol level + 4
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