CHEBI ONTOLOGY - ANNOTATIONS |
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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
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Term: | trovafloxacin |
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Accession: | CHEBI:9763
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browse the term
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Definition: | A 1,8-naphthyridine derivative that is 4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid bearing additional 2,4-difluorophenyl, fluoro and 6-amino-3-azabicyclo[3.1.0]hex-3-yl substituents at positions 1, 6 and 7 respectively. A broad-spectrum antibiotic that was withdrawn from the market due to risk of liver failure. |
Synonyms: | exact_synonym: | 7-[(1R,5S,6s)-6-amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid |
| related_synonym: | Formula=C20H15F3N4O3; InChI=1S/C20H15F3N4O3/c21-8-1-2-15(13(22)3-8)27-7-12(20(29)30)17(28)9-4-14(23)19(25-18(9)27)26-5-10-11(6-26)16(10)24/h1-4,7,10-11,16H,5-6,24H2,(H,29,30)/t10-,11+,16+; InChIKey=WVPSKSLAZQPAKQ-CDMJZVDBSA-N; SMILES=N[C@H]1[C@@H]2CN(C[C@H]12)c1nc2n(cc(C(O)=O)c(=O)c2cc1F)-c1ccc(F)cc1F; trovafloxacine; trovafloxacino; trovafloxacinum |
| xref: | CAS:147059-72-1; DrugBank:DB00685; Drug_Central:2777; HMDB:HMDB0014823; KEGG:C07664; KEGG:D08654 |
| xref_mesh: | MESH:C080163 |
| xref: | PMID:20022474; PMID:20462743; PMID:20538741; PMID:20655887; PMID:21151465; PMID:22305082; PMID:23727874; PMID:24097668; PMID:24525298; Reaxys:8172628; Wikipedia:Trovafloxacin |
| cyclic_relationship: | is_conjugate_base_of CHEBI:77569 |
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Aars1 |
alanyl-tRNA synthetase 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of AARS1 mRNA |
CTD |
PMID:35537566 |
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NCBI chr19:38,999,130...39,021,152
Ensembl chr19:38,999,163...39,021,147
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Aarsd1 |
alanyl-tRNA synthetase domain containing 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of AARSD1 mRNA |
CTD |
PMID:35537566 |
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NCBI chr10:86,340,625...86,353,732
Ensembl chr10:86,340,626...86,353,729
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Aatk |
apoptosis-associated tyrosine kinase |
decreases expression |
ISO |
trovafloxacin results in decreased expression of AATK mRNA |
CTD |
PMID:35537566 |
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NCBI chr10:105,290,752...105,327,219
Ensembl chr10:105,291,585...105,327,112
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Abca2 |
ATP binding cassette subfamily A member 2 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ABCA2 mRNA |
CTD |
PMID:35537566 |
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NCBI chr 3:8,244,515...8,264,545
Ensembl chr 3:8,244,639...8,264,537
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Abca5 |
ATP binding cassette subfamily A member 5 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ABCA5 mRNA |
CTD |
PMID:35537566 |
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NCBI chr10:95,240,159...95,309,195
Ensembl chr10:95,240,154...95,308,976
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Abca7 |
ATP binding cassette subfamily A member 7 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ABCA7 mRNA |
CTD |
PMID:35537566 |
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NCBI chr 7:9,691,452...9,711,466
Ensembl chr 7:9,691,449...9,711,425
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Abca8 |
ATP binding cassette subfamily A member 8 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ABCA8B mRNA |
CTD |
PMID:35537566 |
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NCBI chr10:94,917,520...94,991,199
Ensembl chr10:94,917,520...94,990,988
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Abcb7 |
ATP binding cassette subfamily B member 7 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ABCB7 mRNA |
CTD |
PMID:35537566 |
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NCBI chr X:69,295,598...69,436,775
Ensembl chr X:69,295,552...69,436,858
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Abcd2 |
ATP binding cassette subfamily D member 2 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ABCD2 mRNA |
CTD |
PMID:35537566 |
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NCBI chr 7:122,263,034...122,311,642
Ensembl chr 7:122,263,032...122,311,642
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Abhd15 |
abhydrolase domain containing 15 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ABHD15 mRNA |
CTD |
PMID:35537566 |
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NCBI chr10:62,363,209...62,368,600
Ensembl chr10:62,363,209...62,368,600
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Acaca |
acetyl-CoA carboxylase alpha |
decreases expression |
EXP |
trovafloxacin results in decreased expression of ACACA mRNA |
CTD |
PMID:24136188 |
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NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
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Acap1 |
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ACAP1 mRNA |
CTD |
PMID:35537566 |
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NCBI chr10:54,605,323...54,619,472
Ensembl chr10:54,605,323...54,619,472
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Ackr4 |
atypical chemokine receptor 4 |
increases expression |
ISO |
trovafloxacin results in increased expression of ACKR4 mRNA |
CTD |
PMID:35537566 |
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NCBI chr 8:104,716,537...104,720,972
Ensembl chr 8:104,716,067...104,723,617
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Acot3 |
acyl-CoA thioesterase 3 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ACOT3 mRNA |
CTD |
PMID:35537566 |
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NCBI chr 6:103,682,518...103,688,735
Ensembl chr 6:103,682,596...103,688,427 Ensembl chr 6:103,682,596...103,688,427
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Acot4 |
acyl-CoA thioesterase 4 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ACOT4 mRNA |
CTD |
PMID:35537566 |
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NCBI chr 6:103,668,699...103,674,037
Ensembl chr 6:103,668,753...103,673,917
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Acrbp |
acrosin binding protein |
increases expression |
ISO |
trovafloxacin results in increased expression of ACRBP mRNA |
CTD |
PMID:35537566 |
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NCBI chr 4:157,851,149...157,864,211
Ensembl chr 4:157,841,841...157,864,213
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Acsf2 |
acyl-CoA synthetase family member 2 |
decreases expression |
EXP |
trovafloxacin results in decreased expression of ACSF2 mRNA |
CTD |
PMID:24136188 |
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NCBI chr10:79,504,510...79,546,714
Ensembl chr10:79,504,511...79,546,673
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Acsf3 |
acyl-CoA synthetase family member 3 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ACSF3 mRNA |
CTD |
PMID:35537566 |
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NCBI chr19:50,835,116...50,875,557
Ensembl chr19:50,835,221...50,875,553
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Acss1 |
acyl-CoA synthetase short-chain family member 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ACSS1 mRNA |
CTD |
PMID:35537566 |
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NCBI chr 3:139,450,383...139,500,325
Ensembl chr 3:139,450,383...139,500,325
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Acss2 |
acyl-CoA synthetase short-chain family member 2 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ACSS2 mRNA |
CTD |
PMID:35537566 |
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NCBI chr 3:144,003,808...144,047,452
Ensembl chr 3:144,004,336...144,059,675
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Actb |
actin, beta |
decreases expression |
EXP |
trovafloxacin results in decreased expression of ACTB mRNA |
CTD |
PMID:24136188 |
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NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
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Actg1 |
actin, gamma 1 |
decreases expression |
EXP |
trovafloxacin results in decreased expression of ACTG1 mRNA |
CTD |
PMID:24136188 |
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NCBI chr10:105,619,738...105,622,587
Ensembl chr10:105,619,737...105,624,232 Ensembl chr 3:105,619,737...105,624,232
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Actr3b |
actin related protein 3B |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ACTR3B mRNA |
CTD |
PMID:35537566 |
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NCBI chr 4:9,261,631...9,355,496
Ensembl chr 4:9,262,233...9,355,441
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Acvrl1 |
activin A receptor like type 1 |
increases expression |
ISO |
trovafloxacin results in increased expression of ACVRL1 mRNA |
CTD |
PMID:35537566 |
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NCBI chr 7:132,239,200...132,256,592
Ensembl chr 7:132,239,729...132,256,591
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Acy1 |
aminoacylase 1 |
decreases expression |
EXP |
trovafloxacin results in decreased expression of ACY1 mRNA |
CTD |
PMID:24136188 |
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NCBI chr 8:107,072,354...107,077,756
Ensembl chr 8:107,072,358...107,077,682
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Adam1a |
ADAM metallopeptidase domain 1a |
increases expression |
ISO |
trovafloxacin results in increased expression of ADAM1A mRNA |
CTD |
PMID:35537566 |
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NCBI chr12:35,017,433...35,020,300
Ensembl chr12:35,017,315...35,020,311
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Adam22 |
ADAM metallopeptidase domain 22 |
increases expression |
ISO |
trovafloxacin results in increased expression of ADAM22 mRNA |
CTD |
PMID:35537566 |
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NCBI chr 4:25,716,055...25,970,932
Ensembl chr 4:25,715,990...25,964,962
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Adam33 |
ADAM metallopeptidase domain 33 |
increases expression |
ISO |
trovafloxacin results in increased expression of ADAM33 mRNA |
CTD |
PMID:35537566 |
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NCBI chr 3:118,262,395...118,283,456
Ensembl chr 3:118,271,029...118,283,461
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Adam3a |
ADAM metallopeptidase domain 3A |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ADAM3 mRNA |
CTD |
PMID:35537566 |
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NCBI chr16:67,299,949...67,349,970
Ensembl chr16:67,299,949...67,349,968
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Adam8 |
ADAM metallopeptidase domain 8 |
increases expression |
ISO |
trovafloxacin results in increased expression of ADAM8 mRNA |
CTD |
PMID:35537566 |
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NCBI chr 1:194,776,559...194,789,330
Ensembl chr 1:194,770,060...194,788,801
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Adamts4 |
ADAM metallopeptidase with thrombospondin type 1 motif, 4 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ADAMTS4 mRNA |
CTD |
PMID:35537566 |
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NCBI chr13:83,670,556...83,680,045
Ensembl chr13:83,670,183...83,680,065
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Adap2 |
ArfGAP with dual PH domains 2 |
increases expression decreases expression |
EXP ISO |
trovafloxacin results in increased expression of ADAP2 mRNA trovafloxacin results in decreased expression of ADAP2 mRNA |
CTD |
PMID:24136188 PMID:35537566 |
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NCBI chr10:65,138,006...65,166,147
Ensembl chr10:65,138,020...65,165,604
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Add3 |
adducin 3 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ADD3 mRNA |
CTD |
PMID:35537566 |
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NCBI chr 1:252,147,341...252,255,126
Ensembl chr 1:252,147,386...252,255,124
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Adgre4 |
adhesion G protein-coupled receptor E4 |
increases expression |
ISO |
trovafloxacin results in increased expression of ADGRE4 mRNA |
CTD |
PMID:35537566 |
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NCBI chr 9:9,758,106...9,901,908
Ensembl chr 9:9,760,355...9,900,760
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Adgrl1 |
adhesion G protein-coupled receptor L1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ADGRL1 mRNA |
CTD |
PMID:35537566 |
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NCBI chr19:24,202,405...24,244,137
Ensembl chr19:24,204,360...24,244,139
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Adgrv1 |
adhesion G protein-coupled receptor V1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ADGRV1 mRNA |
CTD |
PMID:35537566 |
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NCBI chr 2:11,331,434...11,911,713
Ensembl chr 2:11,331,442...11,911,688
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Adh7 |
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ADH7 mRNA |
CTD |
PMID:35537566 |
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NCBI chr 2:226,748,724...226,763,183
Ensembl chr 2:226,741,788...226,763,182
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Adipor2 |
adiponectin receptor 2 |
decreases expression |
EXP |
trovafloxacin results in decreased expression of ADIPOR2 mRNA |
CTD |
PMID:24136188 |
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NCBI chr 4:152,524,604...152,588,848
Ensembl chr 4:152,524,623...152,559,355
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Adm |
adrenomedullin |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ADM mRNA |
CTD |
PMID:35537566 |
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NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
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Adra1a |
adrenoceptor alpha 1A |
increases expression |
ISO |
trovafloxacin results in increased expression of ADRA1A mRNA |
CTD |
PMID:35537566 |
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NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500
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Adrb2 |
adrenoceptor beta 2 |
multiple interactions |
ISO |
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of ADRB2 mRNA |
CTD |
PMID:18930950 |
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NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
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Aen |
apoptosis enhancing nuclease |
increases expression |
ISO |
trovafloxacin results in increased expression of AEN mRNA |
CTD |
PMID:35537566 |
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NCBI chr 1:132,815,094...132,824,522
Ensembl chr 1:132,815,142...132,824,523
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Afap1l1 |
actin filament associated protein 1-like 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of AFAP1L1 mRNA |
CTD |
PMID:35537566 |
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NCBI chr18:55,183,786...55,244,174
Ensembl chr18:55,183,786...55,244,146
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Agbl3 |
AGBL carboxypeptidase 3 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of AGBL3 mRNA |
CTD |
PMID:35537566 |
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NCBI chr 4:63,448,789...63,535,538
Ensembl chr 4:63,453,940...63,531,188
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Agbl5 |
AGBL carboxypeptidase 5 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of AGBL5 mRNA |
CTD |
PMID:35537566 |
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NCBI chr 6:25,472,333...25,492,173
Ensembl chr 6:25,472,333...25,490,738
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Agl |
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase |
decreases expression |
ISO |
trovafloxacin results in decreased expression of AGL mRNA |
CTD |
PMID:35537566 |
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NCBI chr 2:204,705,053...204,760,966
Ensembl chr 2:204,705,053...204,760,828
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Agmo |
alkylglycerol monooxygenase |
decreases expression |
ISO |
trovafloxacin results in decreased expression of AGMO mRNA |
CTD |
PMID:35537566 |
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NCBI chr 6:53,986,236...54,317,838
Ensembl chr 6:53,986,292...54,317,623
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Agtpbp1 |
ATP/GTP binding carboxypeptidase 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of AGTPBP1 mRNA |
CTD |
PMID:35537566 |
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NCBI chr17:5,120,540...5,238,874
Ensembl chr17:5,120,609...5,238,869
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Ahcyl1 |
adenosylhomocysteinase-like 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of AHCYL1 mRNA |
CTD |
PMID:35537566 |
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NCBI chr 2:195,294,149...195,328,586
Ensembl chr 2:195,294,153...195,345,815
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Ahi1 |
Abelson helper integration site 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of AHI1 mRNA |
CTD |
PMID:35537566 |
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NCBI chr 1:15,762,485...15,891,213
Ensembl chr 1:15,762,462...15,891,041
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Ak1 |
adenylate kinase 1 |
increases expression |
ISO |
trovafloxacin results in increased expression of AK1 mRNA |
CTD |
PMID:35537566 |
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NCBI chr 3:15,912,431...15,923,045
Ensembl chr 3:15,912,485...15,923,041
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Ak6 |
adenylate kinase 6 |
increases expression |
ISO |
trovafloxacin results in increased expression of AK6 mRNA |
CTD |
PMID:35537566 |
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NCBI chr 2:31,794,316...31,806,375
Ensembl chr 2:31,794,519...31,806,371 Ensembl chr20:31,794,519...31,806,371
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Akap7 |
A-kinase anchoring protein 7 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of AKAP7 mRNA |
CTD |
PMID:35537566 |
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NCBI chr 1:20,087,190...20,217,799
Ensembl chr 1:20,087,373...20,217,797
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Akna |
AT-hook transcription factor |
decreases expression |
ISO |
trovafloxacin results in decreased expression of AKNA mRNA |
CTD |
PMID:35537566 |
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NCBI chr 5:76,777,415...76,824,380
Ensembl chr 5:76,777,415...76,816,017
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Akr1b7 |
aldo-keto reductase family 1, member B7 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of AKR1B7 mRNA |
CTD |
PMID:35537566 |
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NCBI chr 4:63,053,560...63,100,934
Ensembl chr 4:63,076,800...63,089,502
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Akr7a3 |
aldo-keto reductase family 7 member A3 |
decreases expression |
EXP |
trovafloxacin results in decreased expression of AKR7A3 mRNA |
CTD |
PMID:24136188 |
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NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394
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Akt1 |
AKT serine/threonine kinase 1 |
increases phosphorylation multiple interactions |
ISO |
trovafloxacin results in increased phosphorylation of AKT1 protein TNF protein promotes the reaction [trovafloxacin results in increased phosphorylation of AKT1 protein] |
CTD |
PMID:33609687 |
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NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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Aldh16a1 |
aldehyde dehydrogenase 16 family, member A1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ALDH16A1 mRNA |
CTD |
PMID:35537566 |
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NCBI chr 1:95,626,727...95,639,808
Ensembl chr 1:95,613,558...95,640,131
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Aldh18a1 |
aldehyde dehydrogenase 18 family, member A1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ALDH18A1 mRNA |
CTD |
PMID:35537566 |
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NCBI chr 1:239,375,657...239,407,956
Ensembl chr 1:239,375,669...239,407,890
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Aldh1a1 |
aldehyde dehydrogenase 1 family, member A1 |
decreases expression |
EXP |
trovafloxacin results in decreased expression of ALDH1A1 mRNA |
CTD |
PMID:24136188 |
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NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
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Aldh1b1 |
aldehyde dehydrogenase 1 family, member B1 |
decreases expression |
EXP |
trovafloxacin results in decreased expression of ALDH1B1 mRNA |
CTD |
PMID:24136188 |
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NCBI chr 5:60,063,370...60,068,378
Ensembl chr 5:60,063,225...60,068,378
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Aldh1l2 |
aldehyde dehydrogenase 1 family, member L2 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ALDH1L2 mRNA |
CTD |
PMID:35537566 |
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NCBI chr 7:20,254,246...20,305,793
Ensembl chr 7:20,254,233...20,305,776
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Alkbh4 |
alkB homolog 4, lysine demethylase |
increases expression |
ISO |
trovafloxacin results in increased expression of ALKBH4 mRNA |
CTD |
PMID:35537566 |
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NCBI chr12:20,524,030...20,529,947
Ensembl chr12:20,524,030...20,529,947
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Alms1 |
ALMS1, centrosome and basal body associated protein |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ALMS1 mRNA |
CTD |
PMID:35537566 |
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NCBI chr 4:118,125,581...118,226,005
Ensembl chr 4:118,125,607...118,226,005
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Amacr |
alpha-methylacyl-CoA racemase |
decreases expression |
ISO |
trovafloxacin results in decreased expression of AMACR mRNA |
CTD |
PMID:35537566 |
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NCBI chr 2:59,946,158...59,958,255
Ensembl chr 2:59,946,153...59,958,255
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Amd1 |
adenosylmethionine decarboxylase 1 |
decreases expression |
EXP |
trovafloxacin results in decreased expression of AMD1 mRNA |
CTD |
PMID:24136188 |
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NCBI chr20:43,695,783...43,711,476
Ensembl chr20:43,697,237...43,711,476
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Amdhd2 |
amidohydrolase domain containing 2 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of AMDHD2 mRNA |
CTD |
PMID:35537566 |
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NCBI chr10:13,187,579...13,196,148
Ensembl chr10:13,187,578...13,196,095
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Amh |
anti-Mullerian hormone |
increases expression |
ISO |
trovafloxacin results in increased expression of AMH mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 7:8,906,776...8,909,192
Ensembl chr 7:8,906,836...8,909,282
|
|
G |
Amigo3 |
adhesion molecule with Ig like domain 3 |
increases expression |
ISO |
trovafloxacin results in increased expression of AMIGO3 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 8:108,741,899...108,743,425
Ensembl chr 8:108,693,060...108,744,555
|
|
G |
Ammecr1l |
AMMECR1 like |
increases expression |
EXP |
trovafloxacin results in increased expression of AMMECR1L mRNA |
CTD |
PMID:24136188 |
|
NCBI chr18:23,386,114...23,411,177
Ensembl chr18:23,386,903...23,410,920
|
|
G |
Amotl1 |
angiomotin-like 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of AMOTL1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 8:11,348,651...11,467,564
Ensembl chr 8:11,353,674...11,467,573
|
|
G |
Amotl2 |
angiomotin like 2 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of AMOTL2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 8:103,303,368...103,319,161
Ensembl chr 8:103,302,992...103,318,910
|
|
G |
Amz1 |
archaelysin family metallopeptidase 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of AMZ1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr12:13,886,518...13,924,275
Ensembl chr12:13,891,123...13,909,783
|
|
G |
Anapc1 |
anaphase promoting complex subunit 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ANAPC1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 3:115,850,117...115,930,259
Ensembl chr 3:115,850,185...115,930,273
|
|
G |
Anapc5 |
anaphase-promoting complex subunit 5 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ANAPC5 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr12:33,748,709...33,781,709
Ensembl chr12:33,748,735...33,781,781
|
|
G |
Ang |
angiogenin |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ANG mRNA |
CTD |
PMID:35537566 |
|
NCBI chr15:24,312,711...24,323,361
|
|
G |
Angel1 |
angel homolog 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ANGEL1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 6:106,349,125...106,386,202
Ensembl chr 6:106,349,126...106,386,209
|
|
G |
Angel2 |
angel homolog 2 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ANGEL2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr13:102,509,111...102,529,501
Ensembl chr13:102,510,589...102,529,493
|
|
G |
Angptl3 |
angiopoietin-like 3 |
increases expression |
ISO |
trovafloxacin results in increased expression of ANGPTL3 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 5:113,703,007...113,710,044
Ensembl chr 5:113,703,012...113,709,957
|
|
G |
Angptl4 |
angiopoietin-like 4 |
multiple interactions |
ISO |
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of ANGPTL4 mRNA |
CTD |
PMID:18930950 |
|
NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
|
|
G |
Angptl6 |
angiopoietin-like 6 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ANGPTL6 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 8:19,413,617...19,419,925
Ensembl chr 8:19,413,619...19,419,925
|
|
G |
Ankhd1 |
ankyrin repeat and KH domain containing 1 |
increases expression |
EXP |
trovafloxacin results in increased expression of ANKHD1-EIF4EBP3 mRNA |
CTD |
PMID:24136188 |
|
NCBI chr18:28,161,882...28,260,917
Ensembl chr18:28,162,311...28,268,024
|
|
G |
Ankle1 |
ankyrin repeat and LEM domain containing 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ANKLE1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr16:18,076,413...18,082,356
Ensembl chr16:18,076,492...18,083,729
|
|
G |
Ankrd23 |
ankyrin repeat domain 23 |
increases expression |
ISO |
trovafloxacin results in increased expression of ANKRD23 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 9:38,773,234...38,778,705
Ensembl chr 9:38,773,240...38,779,839
|
|
G |
Ankrd55 |
ankyrin repeat domain 55 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ANKRD55 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 2:43,883,877...43,983,820
Ensembl chr 2:43,883,857...43,983,680
|
|
G |
Ankzf1 |
ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ANKZF1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 9:76,688,194...76,695,162
Ensembl chr 9:76,688,194...76,696,469
|
|
G |
Anln |
anillin, actin binding protein |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ANLN mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 8:20,858,227...20,921,602
Ensembl chr 8:20,858,228...20,921,538
|
|
G |
Ano7 |
anoctamin 7 |
increases expression |
ISO |
trovafloxacin results in increased expression of ANO7 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 9:93,917,524...93,945,323
Ensembl chr 9:93,917,524...93,945,323
|
|
G |
Antkmt |
adenine nucleotide translocase lysine methyltransferase |
decreases expression |
ISO |
trovafloxacin results in decreased expression of FAM173A mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:14,812,274...14,814,798
Ensembl chr10:14,812,269...14,814,193
|
|
G |
Antxr2 |
ANTXR cell adhesion molecule 2 |
increases expression |
ISO |
trovafloxacin results in increased expression of ANTXR2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr14:11,541,718...11,682,110
Ensembl chr14:11,541,772...11,682,094
|
|
G |
Anxa9 |
annexin A9 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ANXA9 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 2:182,873,185...182,884,501
Ensembl chr 2:182,872,929...182,883,374
|
|
G |
Ap1g2 |
adaptor related protein complex 1 subunit gamma 2 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of AP1G2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr15:28,571,571...28,579,421
Ensembl chr15:28,571,568...28,589,004
|
|
G |
Ap1s1 |
adaptor related protein complex 1 subunit sigma 1 |
decreases expression |
EXP |
trovafloxacin results in decreased expression of AP1S1 mRNA |
CTD |
PMID:24136188 |
|
NCBI chr12:19,625,267...19,635,792
Ensembl chr12:19,625,332...19,756,713
|
|
G |
Ap5z1 |
adaptor related protein complex 5 subunit zeta 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of AP5Z1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr12:12,093,834...12,109,043
Ensembl chr12:12,093,834...12,108,511
|
|
G |
Apbb3 |
amyloid beta precursor protein binding family B member 3 |
increases expression |
ISO |
trovafloxacin results in increased expression of APBB3 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr18:28,273,168...28,280,347
Ensembl chr18:28,270,545...28,280,094
|
|
G |
Apc2 |
APC regulator of WNT signaling pathway 2 |
increases expression |
ISO |
trovafloxacin results in increased expression of APC2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 7:9,392,336...9,414,364
Ensembl chr 7:9,392,336...9,414,310
|
|
G |
Apeh |
acylaminoacyl-peptide hydrolase |
decreases expression |
ISO |
trovafloxacin results in decreased expression of APEH mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 8:108,773,791...108,782,903
Ensembl chr 8:108,773,794...108,782,933
|
|
G |
Apex1 |
apurinic/apyrimidinic endodeoxyribonuclease 1 |
multiple interactions |
ISO |
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of APEX1 mRNA |
CTD |
PMID:18930950 |
|
NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785
|
|
G |
Apex2 |
apurinic/apyrimidinic endodeoxyribonuclease 2 |
increases expression |
ISO |
trovafloxacin results in increased expression of APEX2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr X:19,425,684...19,508,459
Ensembl chr X:19,487,419...19,508,439
|
|
G |
Apoa5 |
apolipoprotein A5 |
multiple interactions |
ISO |
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of APOA5 mRNA |
CTD |
PMID:18930950 |
|
NCBI chr 8:46,561,180...46,563,818
Ensembl chr 8:46,561,229...46,563,816
|
|
G |
Apoe |
apolipoprotein E |
increases expression |
ISO |
trovafloxacin results in increased expression of APOE mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
|
|
G |
Aqp9 |
aquaporin 9 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of AQP9 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395
|
|
G |
Arf2 |
ADP-ribosylation factor 2 |
increases expression |
ISO |
trovafloxacin results in increased expression of ARF2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:88,867,836...88,889,654
Ensembl chr10:88,867,836...88,889,659
|
|
G |
Arhgap19 |
Rho GTPase activating protein 19 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ARHGAP19 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:240,571,554...240,617,361
Ensembl chr 1:240,580,871...240,617,287
|
|
G |
Arhgap24 |
Rho GTPase activating protein 24 |
decreases expression |
EXP |
trovafloxacin results in decreased expression of ARHGAP24 mRNA |
CTD |
PMID:24136188 |
|
NCBI chr14:6,800,624...7,183,877
Ensembl chr14:6,800,631...7,183,823
|
|
G |
Arhgap26 |
Rho GTPase activating protein 26 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ARHGAP26 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr18:30,835,806...31,237,945
Ensembl chr18:30,838,671...31,235,194
|
|
G |
Arhgap33 |
Rho GTPase activating protein 33 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ARHGAP33 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:85,776,112...85,789,767
Ensembl chr 1:85,776,108...85,789,678
|
|
G |
Arhgap6 |
Rho GTPase activating protein 6 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ARHGAP6 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr X:24,953,464...25,490,003
Ensembl chr X:24,953,464...25,488,663
|
|
G |
Arhgef17 |
Rho guanine nucleotide exchange factor 17 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ARHGEF17 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:155,230,607...155,290,163
Ensembl chr 1:155,233,168...155,290,498
|
|
G |
Arhgef3 |
Rho guanine nucleotide exchange factor 3 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ARHGEF3 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr16:2,301,573...2,581,951
Ensembl chr16:2,300,138...2,581,945
|
|
G |
Arhgef39 |
Rho guanine nucleotide exchange factor 39 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ARHGEF39 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 5:57,752,509...57,756,079
Ensembl chr 5:57,752,509...57,756,109
|
|
G |
Arid5a |
AT-rich interaction domain 5A |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ARID5A mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 9:38,534,612...38,549,467
Ensembl chr 9:38,534,590...38,547,597
|
|
G |
Arid5b |
AT-rich interaction domain 5B |
multiple interactions |
ISO |
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of ARID5B mRNA |
CTD |
PMID:18930950 |
|
NCBI chr20:20,307,731...20,490,746
Ensembl chr20:20,307,731...20,487,433
|
|
G |
Arl10 |
ADP-ribosylation factor like GTPase 10 |
increases expression |
ISO |
trovafloxacin results in increased expression of ARL10 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr17:10,030,213...10,038,625
Ensembl chr17:10,030,213...10,038,703
|
|
G |
Arl11 |
ADP-ribosylation factor like GTPase 11 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ARL11 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr15:35,483,330...35,485,579
Ensembl chr15:35,480,018...35,496,596
|
|
G |
Arl4c |
ADP ribosylation factor like GTPase 4C |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ARL4C mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 9:89,300,335...89,303,770
Ensembl chr 9:89,298,005...89,304,513
|
|
G |
Arl4d |
ADP-ribosylation factor like GTPase 4D |
increases expression |
ISO |
trovafloxacin results in increased expression of ARL4D mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:86,592,054...86,602,843
Ensembl chr10:86,595,661...86,602,836
|
|
G |
Arl6ip5 |
ADP-ribosylation factor like GTPase 6 interacting protein 5 |
increases expression |
ISO |
trovafloxacin results in increased expression of ARL6IP5 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 4:129,810,650...129,838,628
Ensembl chr 4:129,810,645...129,838,608
|
|
G |
Armc2 |
armadillo repeat containing 2 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ARMC2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr20:45,395,859...45,501,808
Ensembl chr20:45,394,127...45,504,819
|
|
G |
Armc7 |
armadillo repeat containing 7 |
increases expression |
ISO |
trovafloxacin results in increased expression of ARMC7 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:100,723,080...100,739,636
Ensembl chr10:100,723,105...100,739,636
|
|
G |
Armt1 |
acidic residue methyltransferase 1 |
decreases expression |
EXP |
trovafloxacin results in decreased expression of ARMT1 mRNA |
CTD |
PMID:24136188 |
|
NCBI chr 1:40,894,558...40,918,302
Ensembl chr 1:40,894,550...40,918,302
|
|
G |
Arrb1 |
arrestin, beta 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ARRB1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:153,837,964...153,912,111
Ensembl chr 1:153,838,078...153,904,061
|
|
G |
Arsa |
arylsulfatase A |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ARSA mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 7:120,542,788...120,547,577
Ensembl chr 7:120,543,362...120,548,783
|
|
G |
Arv1 |
ARV1 homolog, fatty acid homeostasis modulator |
increases expression |
ISO |
trovafloxacin results in increased expression of ARV1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr19:52,692,337...52,704,156
Ensembl chr19:52,692,337...52,704,156
|
|
G |
Asb10 |
ankyrin repeat and SOCS box-containing 10 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ASB10 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 4:10,630,318...10,644,270
Ensembl chr 4:10,630,448...10,639,060
|
|
G |
Asb6 |
ankyrin repeat and SOCS box-containing 6 |
increases expression |
ISO |
trovafloxacin results in increased expression of ASB6 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 3:14,110,628...14,115,274
Ensembl chr 3:14,110,628...14,115,242
|
|
G |
Asf1b |
anti-silencing function 1B histone chaperone |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ASF1B mRNA |
CTD |
PMID:35537566 |
|
NCBI chr19:24,181,024...24,195,604
Ensembl chr19:24,181,028...24,195,549
|
|
G |
Asns |
asparagine synthetase (glutamine-hydrolyzing) |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ASNS mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
|
|
G |
Aspm |
assembly factor for spindle microtubules |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ASPM mRNA |
CTD |
PMID:35537566 |
|
NCBI chr13:51,074,849...51,123,755
Ensembl chr13:51,074,849...51,123,755
|
|
G |
Aspscr1 |
ASPSCR1 tether for SLC2A4, UBX domain containing |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ASPSCR1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:105,952,215...105,990,059
Ensembl chr10:105,952,227...105,989,904
|
|
G |
Asrgl1 |
asparaginase and isoaspartyl peptidase 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ASRGL1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:206,006,103...206,027,115
Ensembl chr 1:206,006,109...206,027,108
|
|
G |
Atf2 |
activating transcription factor 2 |
multiple interactions increases phosphorylation |
ISO |
pyrazolanthrone inhibits the reaction [trovafloxacin results in increased phosphorylation of ATF2 protein] |
CTD |
PMID:24525298 |
|
NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236
|
|
G |
Atf4 |
activating transcription factor 4 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ATF4 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
|
|
G |
Atf5 |
activating transcription factor 5 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ATF5 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:95,295,610...95,299,707
|
|
G |
Atg10 |
autophagy related 10 |
multiple interactions |
ISO |
[trovafloxacin co-treated with TNF protein] results in increased expression of ATG10 mRNA |
CTD |
PMID:33609687 |
|
NCBI chr 2:22,109,304...22,398,313
Ensembl chr 2:22,108,426...22,398,233
|
|
G |
Atg101 |
autophagy related 101 |
increases expression |
ISO |
trovafloxacin results in increased expression of ATG101 mRNA |
CTD |
PMID:33609687 |
|
NCBI chr 7:132,398,477...132,407,643
Ensembl chr 7:132,398,483...132,407,633
|
|
G |
Atg12 |
autophagy related 12 |
increases expression |
ISO |
trovafloxacin results in increased expression of ATG12 mRNA |
CTD |
PMID:33609687 PMID:35537566 |
|
NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418
|
|
G |
Atg14 |
autophagy related 14 |
increases expression multiple interactions |
ISO |
trovafloxacin results in increased expression of ATG14 mRNA TNF protein inhibits the reaction [trovafloxacin results in increased expression of ATG14 mRNA] |
CTD |
PMID:33609687 |
|
NCBI chr15:20,795,750...20,827,113
Ensembl chr15:20,795,750...20,827,113
|
|
G |
Atg16l1 |
autophagy related 16-like 1 |
increases expression multiple interactions |
ISO |
trovafloxacin results in increased expression of ATG16L1 mRNA [trovafloxacin co-treated with TNF protein] results in increased expression of ATG16L1 mRNA |
CTD |
PMID:33609687 |
|
NCBI chr 9:88,420,737...88,457,530
Ensembl chr 9:88,422,038...88,457,529
|
|
G |
Atg16l2 |
autophagy related 16-like 2 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ATG16L2 mRNA |
CTD |
PMID:33609687 |
|
NCBI chr 1:155,687,386...155,703,419
Ensembl chr 1:155,684,564...155,703,420
|
|
G |
Atg2a |
autophagy related 2A |
multiple interactions |
ISO |
[trovafloxacin co-treated with TNF protein] results in increased expression of ATG2A mRNA |
CTD |
PMID:33609687 |
|
NCBI chr 1:203,542,559...203,562,242
Ensembl chr 1:203,542,559...203,562,242
|
|
G |
Atg2b |
autophagy related 2B |
increases expression |
ISO |
trovafloxacin results in increased expression of ATG2B mRNA |
CTD |
PMID:33609687 |
|
NCBI chr 6:124,522,283...124,592,412
Ensembl chr 6:124,525,523...124,592,015
|
|
G |
Atg3 |
autophagy related 3 |
increases expression multiple interactions |
ISO |
trovafloxacin results in increased expression of ATG3 mRNA [trovafloxacin co-treated with TNF protein] results in increased expression of ATG3 mRNA |
CTD |
PMID:33609687 |
|
NCBI chr11:55,624,914...55,653,249
Ensembl chr11:55,624,917...55,653,224
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G |
Atg4a |
autophagy related 4A, cysteine peptidase |
increases expression multiple interactions |
ISO |
trovafloxacin results in increased expression of ATG4A mRNA [trovafloxacin co-treated with TNF protein] results in increased expression of ATG4A mRNA |
CTD |
PMID:33609687 |
|
NCBI chr X:104,665,345...104,765,271
Ensembl chr X:104,665,345...104,765,268
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|
G |
Atg4c |
autophagy related 4C, cysteine peptidase |
multiple interactions |
ISO |
[trovafloxacin co-treated with TNF protein] results in decreased expression of ATG4C mRNA |
CTD |
PMID:33609687 |
|
NCBI chr 5:113,867,218...113,935,534
Ensembl chr 5:113,867,092...113,934,830
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|
G |
Atg5 |
autophagy related 5 |
affects response to substance multiple interactions increases expression |
ISO |
ATG5 protein affects the susceptibility to trovafloxacin ATG5 protein affects the reaction [trovafloxacin results in increased cleavage of CASP3 protein]; ATG5 protein affects the reaction [trovafloxacin results in increased cleavage of PARP1 protein]; ATG5 protein affects the reaction [trovafloxacin results in increased phosphorylation of MAPK1 protein]; ATG5 protein affects the reaction [trovafloxacin results in increased phosphorylation of MAPK3 protein]; ATG5 protein affects the reaction [trovafloxacin results in increased phosphorylation of MAPK8 protein]; TNF protein inhibits the reaction [trovafloxacin results in increased expression of ATG5 mRNA] |
CTD |
PMID:33609687 |
|
NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209
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|
G |
Atg9b |
autophagy related 9B |
increases expression multiple interactions |
ISO |
trovafloxacin results in increased expression of ATG9B mRNA TNF protein promotes the reaction [trovafloxacin results in increased expression of ATG9B mRNA]; trovafloxacin promotes the reaction [TNF protein results in increased expression of ATG9B mRNA] |
CTD |
PMID:33609687 |
|
NCBI chr 4:10,784,934...10,793,832
Ensembl chr 4:10,786,114...10,793,651
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|
G |
Atm |
ATM serine/threonine kinase |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ATM mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
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|
G |
Atosb |
atos homolog B |
increases expression |
ISO |
trovafloxacin results in increased expression of ATOSB mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 5:57,260,839...57,274,524
Ensembl chr 5:57,260,841...57,268,892
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|
G |
Atp11c |
ATPase phospholipid transporting 11C |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ATP11C mRNA |
CTD |
PMID:35537566 |
|
NCBI chr X:138,564,459...138,752,116
Ensembl chr X:138,565,836...138,751,204
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|
G |
Atp1a3 |
ATPase Na+/K+ transporting subunit alpha 3 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ATP1A3 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:80,572,790...80,601,936
Ensembl chr 1:80,572,796...80,601,918
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|
G |
Atp5mc3 |
ATP synthase membrane subunit c locus 3 |
increases expression |
ISO |
trovafloxacin results in increased expression of ATP5MC3 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 3:58,810,535...58,813,185
Ensembl chr 3:58,810,535...58,814,279
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|
G |
Atp5me |
ATP synthase membrane subunit e |
increases expression |
ISO |
trovafloxacin results in increased expression of ATP5ME mRNA |
CTD |
PMID:35537566 |
|
NCBI chr14:1,319,868...1,320,996
Ensembl chr14:1,319,868...1,321,013
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|
G |
Atp5mk |
ATP synthase membrane subunit K |
increases expression |
ISO |
trovafloxacin results in increased expression of ATP5MK mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:245,973,910...245,980,702
Ensembl chr 1:245,973,914...245,980,761 Ensembl chr10:245,973,914...245,980,761
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|
G |
Atp6v0e2 |
ATPase, H+ transporting V0 subunit e2 |
decreases expression increases expression |
EXP ISO |
trovafloxacin results in decreased expression of ATP6V0E2 mRNA trovafloxacin results in increased expression of ATP6V0E2 mRNA |
CTD |
PMID:24136188 PMID:35537566 |
|
NCBI chr 4:77,484,868...77,488,016
Ensembl chr 4:77,482,226...77,488,777
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|
G |
Atp8a1 |
ATPase phospholipid transporting 8A1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ATP8A1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr14:40,315,013...40,557,572
Ensembl chr14:40,315,049...40,554,611
|
|
G |
Atr |
ATR serine/threonine kinase |
multiple interactions decreases expression |
ISO |
4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine inhibits the reaction [[trovafloxacin co-treated with TNF protein] results in increased phosphorylation of ATR protein]; 4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine inhibits the reaction [trovafloxacin results in increased phosphorylation of ATR protein]; [trovafloxacin co-treated with TNF protein] results in increased phosphorylation of and results in increased activity of ATR protein; trovafloxacin results in increased phosphorylation of and results in increased activity of ATR protein; U 0126 inhibits the reaction [trovafloxacin results in increased activity of ATR protein] trovafloxacin results in decreased expression of ATR mRNA |
CTD |
PMID:25748550 PMID:35537566 |
|
NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136
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|
G |
Atrn |
attractin |
increases expression |
EXP |
trovafloxacin results in increased expression of ATRN mRNA |
CTD |
PMID:24136188 |
|
NCBI chr 3:118,110,320...118,244,326
Ensembl chr 3:118,110,229...118,244,322
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|
G |
Atxn7l3b |
ataxin 7-like 3B |
increases expression |
ISO |
trovafloxacin results in increased expression of ATXN7L3B mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 7:48,322,451...48,325,975
Ensembl chr 7:48,321,755...48,328,878
|
|
G |
Aunip |
aurora kinase A and ninein interacting protein |
decreases expression |
ISO |
trovafloxacin results in decreased expression of AUNIP mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 5:146,722,329...146,734,924
Ensembl chr 5:146,722,337...146,736,501
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|
G |
Aurka |
aurora kinase A |
decreases expression |
ISO |
trovafloxacin results in decreased expression of AURKA mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390
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|
G |
Aurkb |
aurora kinase B |
decreases expression |
ISO |
trovafloxacin results in decreased expression of AURKB mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837
|
|
G |
B2m |
beta-2 microglobulin |
multiple interactions |
ISO |
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of B2M mRNA |
CTD |
PMID:18930950 |
|
NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766
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|
G |
B4galnt2 |
beta-1,4-N-acetyl-galactosaminyl transferase 2 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of B4GALNT2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:80,801,594...80,828,005
Ensembl chr10:80,802,941...80,857,700
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|
G |
Baiap2l1 |
BAR/IMD domain containing adaptor protein 2 like 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of BAIAP2L1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr12:10,250,434...10,339,937
Ensembl chr12:10,250,473...10,339,928
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|
G |
Bard1 |
BRCA1 associated RING domain 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of BARD1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 9:72,616,070...72,694,553
Ensembl chr 9:72,623,155...72,694,265
|
|
G |
Batf2 |
basic leucine zipper ATF-like transcription factor 2 |
increases expression |
ISO |
trovafloxacin results in increased expression of BATF2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:203,467,291...203,479,428
Ensembl chr 1:203,468,097...203,475,889
|
|
G |
Bbs9 |
Bardet-Biedl syndrome 9 |
increases expression |
ISO |
trovafloxacin results in increased expression of BBS9 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 8:21,013,865...21,437,934
Ensembl chr 8:21,013,944...21,437,930
|
|
G |
Bcar3 |
BCAR3 adaptor protein, NSP family member |
increases expression |
ISO |
trovafloxacin results in increased expression of BCAR3 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 2:210,525,260...210,638,674
Ensembl chr 2:210,525,260...210,638,798
|
|
G |
Bcat1 |
branched chain amino acid transaminase 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of BCAT1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 4:177,964,834...178,046,573
Ensembl chr 4:177,964,834...178,046,597
|
|
G |
Bcdin3d |
BCDIN3 domain containing RNA methyltransferase |
decreases expression |
ISO |
trovafloxacin results in decreased expression of BCDIN3D mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 7:130,605,540...130,610,134
Ensembl chr 7:130,605,541...130,610,115
|
|
G |
Bco2 |
beta-carotene oxygenase 2 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of BCO2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 8:50,882,174...50,907,676
Ensembl chr 8:50,882,181...50,915,467
|
|
G |
Bdh1 |
3-hydroxybutyrate dehydrogenase 1 |
increases expression |
ISO |
trovafloxacin results in increased expression of BDH1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr11:69,302,534...69,343,173
Ensembl chr11:69,302,534...69,337,671
|
|
G |
Bdh2 |
3-hydroxybutyrate dehydrogenase 2 |
increases expression |
ISO |
trovafloxacin results in increased expression of BDH2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 2:223,702,410...223,723,076
Ensembl chr 2:223,702,412...223,723,072
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|
G |
Bend6 |
BEN domain containing 6 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of BEND6 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 9:36,081,033...36,135,309
Ensembl chr 9:36,081,484...36,135,228
|
|
G |
Bet1l |
Bet1 golgi vesicular membrane trafficking protein-like |
increases expression |
ISO |
trovafloxacin results in increased expression of BET1L mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:195,931,407...195,935,072
Ensembl chr 1:195,931,411...195,935,040
|
|
G |
Bhlhe40 |
basic helix-loop-helix family, member e40 |
multiple interactions |
ISO |
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of BHLHE40 mRNA |
CTD |
PMID:18930950 |
|
NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774
|
|
G |
Birc2 |
baculoviral IAP repeat-containing 2 |
multiple interactions decreases expression |
ISO |
trovafloxacin inhibits the reaction [TNF protein results in increased expression of BIRC2 mRNA] trovafloxacin results in decreased expression of BIRC2 mRNA [trovafloxacin co-treated with TNF protein] results in decreased expression of BIRC2 mRNA trovafloxacin results in decreased expression of BIRC2 protein |
CTD |
PMID:32035082 |
|
NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732
|
|
G |
Birc3 |
baculoviral IAP repeat-containing 3 |
multiple interactions decreases expression |
ISO |
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of BIRC3 mRNA trovafloxacin results in decreased expression of BIRC3 mRNA [trovafloxacin co-treated with TNF protein] results in increased expression of BIRC3 mRNA |
CTD |
PMID:18930950 PMID:32035082 |
|
NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
|
|
G |
Birc5 |
baculoviral IAP repeat-containing 5 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of BIRC5 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
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|
G |
Blm |
BLM RecQ like helicase |
decreases expression |
ISO |
trovafloxacin results in decreased expression of BLM mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:134,409,832...134,496,073
Ensembl chr 1:134,409,857...134,484,312
|
|
G |
Bloc1s2 |
biogenesis of lysosomal organelles complex-1, subunit 2 |
increases expression |
ISO |
trovafloxacin results in increased expression of BLOC1S2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:243,024,611...243,031,749
Ensembl chr 1:243,024,614...243,031,653
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|
G |
Blzf1 |
basic leucine zipper nuclear factor 1 |
increases expression |
ISO |
trovafloxacin results in increased expression of BLZF1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr13:76,641,757...76,656,977
Ensembl chr13:76,641,515...76,656,999
|
|
G |
Bmf |
Bcl2 modifying factor |
decreases expression |
ISO |
trovafloxacin results in decreased expression of BMF mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145
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|
G |
Bok |
BCL2 family apoptosis regulator BOK |
decreases expression |
ISO |
trovafloxacin results in decreased expression of BOK mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 9:94,223,493...94,234,476
Ensembl chr 9:94,223,389...94,234,476
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|
G |
Bora |
bora, aurora kinase A activator |
decreases expression |
ISO |
trovafloxacin results in decreased expression of BORA mRNA |
CTD |
PMID:35537566 |
|
NCBI chr15:75,797,624...75,835,599
Ensembl chr15:75,797,891...75,821,322
|
|
G |
Borcs5 |
BLOC-1 related complex subunit 5 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of BORCS5 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 4:167,458,640...167,543,556
Ensembl chr 4:167,473,177...167,540,993
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|
G |
Bphl |
biphenyl hydrolase like |
decreases expression |
ISO |
trovafloxacin results in decreased expression of BPHL mRNA |
CTD |
PMID:35537566 |
|
NCBI chr17:30,800,939...30,837,277
Ensembl chr17:30,799,629...30,837,288
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|
G |
Bpnt1 |
3'(2'), 5'-bisphosphate nucleotidase 1 |
decreases expression |
EXP |
trovafloxacin results in decreased expression of BPNT1 mRNA |
CTD |
PMID:24136188 |
|
NCBI chr13:96,865,634...96,893,506
Ensembl chr13:96,868,580...96,893,503
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|
G |
Brca1 |
BRCA1, DNA repair associated |
decreases expression |
ISO |
trovafloxacin results in decreased expression of BRCA1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
|
|
G |
Brca2 |
BRCA2, DNA repair associated |
decreases expression |
ISO |
trovafloxacin results in decreased expression of BRCA2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
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|
G |
Brd2 |
bromodomain containing 2 |
increases expression |
ISO |
trovafloxacin results in increased expression of BRD2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr20:4,727,078...4,735,389
Ensembl chr20:4,728,151...4,735,388
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|
G |
Brdt |
bromodomain testis associated |
decreases expression |
ISO |
trovafloxacin results in decreased expression of BRDT mRNA |
CTD |
PMID:35537566 |
|
NCBI chr14:2,387,372...2,445,857
Ensembl chr14:2,387,796...2,445,842
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|
G |
Brip1 |
BRCA1 interacting helicase 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of BRIP1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:70,907,266...71,031,502
Ensembl chr10:70,907,371...71,030,324
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|
G |
Bsdc1 |
BSD domain containing 1 |
increases expression |
ISO |
trovafloxacin results in increased expression of BSDC1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 5:141,798,918...141,827,091
Ensembl chr 5:141,798,981...141,827,092
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|
G |
Bst2 |
bone marrow stromal cell antigen 2 |
decreases expression increases expression |
EXP ISO |
trovafloxacin results in decreased expression of BST2 mRNA trovafloxacin results in increased expression of BST2 mRNA |
CTD |
PMID:24136188 PMID:35537566 |
|
NCBI chr16:18,216,605...18,220,979
Ensembl chr16:18,217,407...18,220,979
|
|
G |
Bub1 |
BUB1 mitotic checkpoint serine/threonine kinase |
decreases expression |
ISO |
trovafloxacin results in decreased expression of BUB1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650
|
|
G |
Bub1b |
BUB1 mitotic checkpoint serine/threonine kinase B |
decreases expression |
ISO |
trovafloxacin results in decreased expression of BUB1B mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547
|
|
G |
C11h21orf91 |
similar to human chromosome 21 open reading frame 91 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of D16ERTD472E mRNA |
CTD |
PMID:35537566 |
|
NCBI chr11:17,229,129...17,262,307
Ensembl chr11:17,229,138...17,262,483
|
|
G |
C1d |
C1D nuclear receptor corepressor |
increases expression |
ISO |
trovafloxacin results in increased expression of C1D mRNA |
CTD |
PMID:35537566 |
|
NCBI chr14:91,660,951...91,673,177
Ensembl chr14:91,660,989...91,672,852
|
|
G |
C1qtnf12 |
C1q and TNF related 12 |
increases expression |
ISO |
trovafloxacin results in increased expression of FAM132A mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 5:166,551,628...166,556,003
Ensembl chr 5:166,551,628...166,556,003
|
|
G |
C1qtnf6 |
C1q and TNF related 6 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of C1QTNF6 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 7:110,077,867...110,084,584
Ensembl chr 7:110,077,878...110,084,412
|
|
G |
C1rl |
complement C1r subcomponent like |
decreases expression |
ISO |
trovafloxacin results in decreased expression of C1RL mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 4:157,394,183...157,410,771
Ensembl chr 4:157,394,200...157,410,134
|
|
G |
C2cd5 |
C2 calcium-dependent domain containing 5 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of C2CD5 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 4:175,969,544...176,055,597
Ensembl chr 4:175,969,545...176,055,558
|
|
G |
C2h4orf33 |
similar to human chromosome 4 open reading frame 33 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of D3ERTD751E mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 2:124,764,263...124,830,001
Ensembl chr 2:124,769,940...124,832,449
|
|
G |
C5h1orf50 |
similar to human chromosome 1 open reading frame 50 |
increases expression |
EXP |
trovafloxacin results in increased expression of C5H1ORF50 mRNA |
CTD |
PMID:24136188 |
|
NCBI chr 5:132,837,135...132,841,744
Ensembl chr 5:132,836,506...132,841,762
|
|
G |
C5l1 |
complement C5 like 1 |
increases expression |
EXP |
trovafloxacin results in increased expression of C5L1 mRNA |
CTD |
PMID:24136188 |
|
NCBI chr 3:18,401,716...18,420,064
Ensembl chr 3:18,404,899...18,420,054
|
|
G |
C8h11orf54 |
similar to human chromosome 11 open reading frame 54 |
decreases expression |
EXP |
trovafloxacin results in decreased expression of C8H11ORF54 mRNA |
CTD |
PMID:24136188 |
|
NCBI chr 8:12,123,839...12,146,412
Ensembl chr 8:12,123,823...12,146,473
|
|
G |
Cacna1d |
calcium voltage-gated channel subunit alpha1 D |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CACNA1D mRNA |
CTD |
PMID:35537566 |
|
NCBI chr16:5,227,157...5,521,163
Ensembl chr16:5,228,306...5,668,215
|
|
G |
Cad |
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CAD mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 6:25,292,133...25,315,078
Ensembl chr 6:25,292,133...25,319,861
|
|
G |
Calhm2 |
calcium homeostasis modulator family member 2 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CALHM2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:246,022,324...246,028,050
Ensembl chr 1:246,022,324...246,028,218
|
|
G |
Calhm6 |
calcium homeostasis modulator family member 6 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of FAM26F mRNA |
CTD |
PMID:35537566 |
|
NCBI chr20:26,095,591...26,097,336
Ensembl chr20:26,095,592...26,097,278
|
|
G |
Camkk2 |
calcium/calmodulin-dependent protein kinase kinase 2 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CAMKK2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr12:33,791,023...33,845,000
Ensembl chr12:33,791,052...33,843,279
|
|
G |
Camsap3 |
calmodulin regulated spectrin-associated protein family, member 3 |
increases expression |
ISO |
trovafloxacin results in increased expression of CAMSAP3 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr12:1,643,062...1,666,685
Ensembl chr12:1,643,251...1,666,685
|
|
G |
Caprin1 |
cell cycle associated protein 1 |
multiple interactions |
ISO |
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of CAPRIN1 mRNA |
CTD |
PMID:18930950 |
|
NCBI chr 3:90,152,305...90,230,447
Ensembl chr 3:90,153,620...90,230,502
|
|
G |
Car12 |
carbonic anhydrase 12 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CAR12 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 8:67,274,739...67,330,428
Ensembl chr 8:67,274,359...67,330,440
|
|
G |
Car7 |
carbonic anhydrase 7 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CAR7 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr19:429,063...438,478
Ensembl chr19:429,075...438,467
|
|
G |
Card11 |
caspase recruitment domain family, member 11 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CARD11 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr12:13,621,140...13,758,115
Ensembl chr12:13,621,087...13,758,112
|
|
G |
Carmil2 |
capping protein regulator and myosin 1 linker 2 |
increases expression |
ISO |
trovafloxacin results in increased expression of RLTPR mRNA |
CTD |
PMID:35537566 |
|
NCBI chr19:33,571,255...33,586,783
Ensembl chr19:33,574,257...33,586,965
|
|
G |
Cars1 |
cysteinyl-tRNA synthetase 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CARS1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:198,753,689...198,796,016
Ensembl chr 1:198,753,691...198,795,941
|
|
G |
Casd1 |
CAS1 domain containing 1 |
multiple interactions |
ISO |
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of CASD1 mRNA |
CTD |
PMID:18930950 |
|
NCBI chr 4:32,659,196...32,739,228
Ensembl chr 4:32,658,748...32,739,202
|
|
G |
Casp3 |
caspase 3 |
multiple interactions increases activity increases cleavage |
ISO |
[TNF protein co-treated with IL6 protein co-treated with IL1B protein] promotes the reaction [trovafloxacin results in increased activity of CASP3 protein]; [TNF protein co-treated with trovafloxacin] results in increased activity of CASP3 protein; [trovafloxacin co-treated with [TNF protein co-treated with IL6 protein co-treated with IL1B protein]] results in increased activity of CASP3 protein; [trovafloxacin co-treated with IL1B protein] results in increased activity of CASP3 protein; [trovafloxacin co-treated with IL6 protein] results in increased activity of CASP3 protein; [trovafloxacin co-treated with TNF protein] results in increased activity of CASP3 protein; ATG5 protein affects the reaction [trovafloxacin results in increased cleavage of CASP3 protein]; U 0126 inhibits the reaction [[TNF protein co-treated with trovafloxacin] results in increased activity of CASP3 protein] [TNF protein co-treated with trovafloxacin] results in increased cleavage of CASP3 protein |
CTD |
PMID:19638433 PMID:24097668 PMID:25748550 PMID:30876886 PMID:33609687 |
|
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
|
|
G |
Casp6 |
caspase 6 |
increases expression |
EXP |
trovafloxacin results in increased expression of CASP6 mRNA |
CTD |
PMID:24136188 |
|
NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502
|
|
G |
Casp7 |
caspase 7 |
decreases expression |
EXP |
trovafloxacin results in decreased expression of CASP7 mRNA |
CTD |
PMID:24136188 |
|
NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729
|
|
G |
Casp8 |
caspase 8 |
multiple interactions |
ISO |
[trovafloxacin co-treated with TNF protein] results in increased activity of CASP8 protein |
CTD |
PMID:24097668 |
|
NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
|
|
G |
Casp9 |
caspase 9 |
multiple interactions |
ISO |
[trovafloxacin co-treated with TNF protein] results in increased activity of CASP9 protein |
CTD |
PMID:24097668 |
|
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
|
|
G |
Cav1 |
caveolin 1 |
increases expression |
ISO |
trovafloxacin results in increased expression of CAV1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
|
|
G |
Cbfa2t3 |
CBFA2/RUNX1 partner transcriptional co-repressor 3 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CBFA2T3 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr19:50,679,897...50,750,028
Ensembl chr19:50,680,729...50,749,610
|
|
G |
Cbs |
cystathionine beta synthase |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CBS mRNA |
CTD |
PMID:35537566 |
|
NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764
|
|
G |
Cc2d1b |
coiled-coil and C2 domain containing 1B |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CC2D1B mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 5:123,353,289...123,367,343
Ensembl chr 5:123,353,292...123,367,318
|
|
G |
Cc2d2a |
coiled-coil and C2 domain containing 2A |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CC2D2A mRNA |
CTD |
PMID:35537566 |
|
NCBI chr14:67,349,004...67,435,883
Ensembl chr14:67,351,353...67,435,949
|
|
G |
Ccdc137 |
coiled-coil domain containing 137 |
increases expression |
ISO |
trovafloxacin results in increased expression of CCDC137 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:105,730,776...105,737,158
Ensembl chr10:105,730,739...105,737,158
|
|
G |
Ccdc15 |
coiled-coil domain containing 15 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CCDC15 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 8:36,991,147...37,068,849
Ensembl chr 8:36,998,867...37,068,919
|
|
G |
Ccdc163 |
coiled-coil domain containing 163 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CCDC163 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 5:130,172,014...130,178,934
Ensembl chr 5:130,172,774...130,178,929
|
|
G |
Ccdc18 |
coiled-coil domain containing 18 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CCDC18 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr14:1,501,749...1,607,672
Ensembl chr14:1,501,784...1,607,711
|
|
G |
Ccdc181 |
coiled-coil domain containing 181 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CCDC181 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr13:76,624,567...76,638,224
Ensembl chr13:76,624,567...76,638,224
|
|
G |
Ccdc34 |
coiled-coil domain containing 34 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CCDC34 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 3:96,553,074...96,588,310
Ensembl chr 3:96,552,992...96,588,146
|
|
G |
Ccdc6 |
coiled-coil domain containing 6 |
multiple interactions |
ISO |
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of CCDC6 mRNA |
CTD |
PMID:18930950 |
|
NCBI chr20:18,432,177...18,528,186
Ensembl chr20:18,433,695...18,528,658
|
|
G |
Ccdc62 |
coiled-coil domain containing 62 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CCDC62 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr12:32,623,170...32,659,912
Ensembl chr12:32,623,170...32,660,017
|
|
G |
Ccdc74a |
coiled-coil domain containing 74A |
increases expression |
ISO |
trovafloxacin results in increased expression of CCDC74A mRNA |
CTD |
PMID:35537566 |
|
NCBI chr11:83,355,888...83,360,269
Ensembl chr11:83,355,874...83,360,378
|
|
G |
Ccdc86 |
coiled-coil domain containing 86 |
increases expression |
ISO |
trovafloxacin results in increased expression of CCDC86 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:207,590,167...207,596,547
Ensembl chr 1:207,590,168...207,596,544
|
|
G |
Ccdc91 |
coiled-coil domain containing 91 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CCDC91 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 4:180,402,327...180,574,364
Ensembl chr 4:180,402,376...180,574,364
|
|
G |
Ccdc96 |
coiled-coil domain containing 96 |
increases expression |
ISO |
trovafloxacin results in increased expression of CCDC96 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr14:74,276,568...74,279,072
Ensembl chr14:74,276,960...74,278,888
|
|
G |
Ccl2 |
C-C motif chemokine ligand 2 |
multiple interactions |
ISO |
trovafloxacin promotes the reaction [TNF protein results in increased expression of CCL2 protein] |
CTD |
PMID:19638433 |
|
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
|
|
G |
Ccl22 |
C-C motif chemokine ligand 22 |
increases expression |
ISO |
trovafloxacin results in increased expression of CCL22 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr19:10,257,602...10,264,373
Ensembl chr19:10,257,601...10,264,400
|
|
G |
Ccl3 |
C-C motif chemokine ligand 3 |
increases expression |
ISO |
trovafloxacin results in increased expression of CCL3 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
|
|
G |
Ccl4 |
C-C motif chemokine ligand 4 |
increases expression |
ISO |
trovafloxacin results in increased expression of CCL4 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231
|
|
G |
Ccna2 |
cyclin A2 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CCNA2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
|
|
G |
Ccnb1 |
cyclin B1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CCNB1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
|
|
G |
Ccnb2 |
cyclin B2 |
decreases expression |
EXP ISO |
trovafloxacin results in decreased expression of CCNB2 mRNA |
CTD |
PMID:24136188 PMID:35537566 |
|
NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
|
|
G |
Ccnd1 |
cyclin D1 |
decreases expression increases expression |
EXP ISO |
trovafloxacin results in decreased expression of CCND1 mRNA trovafloxacin results in increased expression of CCND1 mRNA |
CTD |
PMID:24136188 PMID:35537566 |
|
NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
|
|
G |
Ccng2 |
cyclin G2 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CCNG2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr14:14,804,321...14,812,819
Ensembl chr14:14,804,322...14,812,830
|
|
G |
Ccnj |
cyclin J |
increases expression |
ISO |
trovafloxacin results in increased expression of CCNJ mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:239,659,588...239,677,367
|
|
G |
Ccnl1 |
cyclin L1 |
increases expression |
ISO |
trovafloxacin results in increased expression of CCNL1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 2:150,184,865...150,199,524
Ensembl chr 2:150,184,798...150,197,368
|
|
G |
Ccr10 |
C-C motif chemokine receptor 10 |
increases expression |
ISO |
trovafloxacin results in increased expression of CCR10 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:86,108,551...86,110,988
Ensembl chr10:86,108,551...86,110,988
|
|
G |
Ccsap |
centriole, cilia and spindle-associated protein |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CCSAP mRNA |
CTD |
PMID:35537566 |
|
NCBI chr19:51,824,954...51,843,469
Ensembl chr19:51,826,994...51,842,753
|
|
G |
Cd101 |
CD101 molecule |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CD101 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 2:188,422,989...188,459,536
Ensembl chr 2:188,422,351...188,459,502
|
|
G |
Cd109 |
CD109 molecule |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CD109 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 8:79,454,480...79,569,195
Ensembl chr 8:79,454,480...79,569,194
|
|
G |
Cd200r1l |
CD200 receptor 1-like |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CD200R4 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr11:55,842,632...55,860,914
Ensembl chr11:55,842,634...55,885,680
|
|
G |
Cd207 |
CD207 molecule |
increases expression |
ISO |
trovafloxacin results in increased expression of CD207 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 4:116,155,229...116,161,587
Ensembl chr 4:116,155,212...116,161,518
|
|
G |
Cd24 |
CD24 molecule |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CD24A mRNA |
CTD |
PMID:35537566 |
|
NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662
|
|
G |
Cd244 |
CD244 molecule |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CD244 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr13:84,051,339...84,082,864
Ensembl chr13:84,052,493...84,074,492
|
|
G |
Cd27 |
CD27 molecule |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CD27 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 4:158,030,700...158,035,862
Ensembl chr 4:158,030,703...158,035,592
|
|
G |
Cd300lb |
CD300 molecule-like family member b |
increases expression |
ISO |
trovafloxacin results in increased expression of CD300LB mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:99,964,801...99,974,790
Ensembl chr10:99,964,801...99,974,790
|
|
G |
Cd33 |
CD33 molecule |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CD33 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:93,935,418...93,940,452
Ensembl chr 1:93,930,971...93,950,149
|
|
G |
Cd36 |
CD36 molecule |
decreases expression |
EXP |
trovafloxacin results in decreased expression of CD36 mRNA |
CTD |
PMID:24136188 |
|
NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
|
|
G |
Cd5 |
Cd5 molecule |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CD5 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:207,365,337...207,386,313
Ensembl chr 1:207,365,337...207,386,313
|
|
G |
Cd80 |
Cd80 molecule |
increases expression |
ISO |
trovafloxacin results in increased expression of CD80 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030
|
|
G |
Cd86 |
CD86 molecule |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CD86 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
|
|
G |
Cd8b |
CD8 subunit beta |
multiple interactions |
ISO |
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of CD8B mRNA |
CTD |
PMID:18930950 |
|
NCBI chr 4:103,312,596...103,328,523
Ensembl chr 4:103,312,578...103,328,553
|
|
G |
Cdc20 |
cell division cycle 20 |
decreases expression |
EXP ISO |
trovafloxacin results in decreased expression of CDC20 mRNA |
CTD |
PMID:24136188 PMID:35537566 |
|
NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
|
|
G |
Cdc25b |
cell division cycle 25B |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CDC25B mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 3:118,407,127...118,417,272
Ensembl chr 3:118,407,128...118,417,272
|
|
G |
Cdc25c |
cell division cycle 25C |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CDC25C mRNA |
CTD |
PMID:35537566 |
|
NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185
|
|
G |
Cdc26 |
cell division cycle 26 |
increases expression |
ISO |
trovafloxacin results in increased expression of CDC26 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 5:75,844,852...75,859,830
|
|
G |
Cdc34 |
cell division cycle 34, ubiqiutin conjugating enzyme |
increases expression |
ISO |
trovafloxacin results in increased expression of CDC34 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 7:10,017,588...10,023,586
Ensembl chr 7:10,017,588...10,023,186
|
|
G |
Cdc42ep4 |
CDC42 effector protein 4 |
increases expression |
EXP |
trovafloxacin results in increased expression of CDC42EP4 mRNA |
CTD |
PMID:24136188 |
|
NCBI chr10:98,772,613...98,797,924
Ensembl chr10:98,772,495...98,797,695
|
|
G |
Cdca2 |
cell division cycle associated 2 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CDCA2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr15:41,895,946...41,942,226
Ensembl chr15:41,895,901...41,941,611
|
|
G |
Cdca3 |
cell division cycle associated 3 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CDCA3 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 4:157,634,775...157,638,799
Ensembl chr 4:157,634,928...157,638,799
|
|
G |
Cdca5 |
cell division cycle associated 5 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CDCA5 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:203,378,550...203,392,027
Ensembl chr 1:203,378,577...203,392,023
|
|
G |
Cdca8 |
cell division cycle associated 8 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CDCA8 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 5:137,176,414...137,198,686
Ensembl chr 5:137,176,417...137,198,629
|
|
G |
Cdin1 |
CDAN1 interacting nuclease 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CDIN1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 3:102,441,553...102,646,935
Ensembl chr 3:102,441,704...102,646,682
|
|
G |
Cdk1 |
cyclin-dependent kinase 1 |
decreases expression |
EXP ISO |
trovafloxacin results in decreased expression of CDK1 mRNA |
CTD |
PMID:24136188 PMID:35537566 |
|
NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
|
|
G |
Cdk10 |
cyclin-dependent kinase 10 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CDK10 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr19:51,260,012...51,273,009
Ensembl chr19:51,261,356...51,269,078
|
|
G |
Cdk16 |
cyclin-dependent kinase 16 |
multiple interactions |
ISO |
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of CDK16 mRNA |
CTD |
PMID:18930950 |
|
NCBI chr X:1,492,814...1,504,309
Ensembl chr X:1,492,814...1,504,148
|
|
G |
Cdk2ap2 |
cyclin-dependent kinase 2 associated protein 2 |
increases expression |
ISO |
trovafloxacin results in increased expression of CDK2AP2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:201,391,056...201,393,137
Ensembl chr 1:201,391,466...201,393,137
|
|
G |
Cdk5rap2 |
CDK5 regulatory subunit associated protein 2 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CDK5RAP2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 5:83,792,282...83,961,129
Ensembl chr 5:83,792,284...83,960,782
|
|
G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
multiple interactions increases expression |
ISO |
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of CDKN1A mRNA trovafloxacin results in increased expression of CDKN1A mRNA |
CTD |
PMID:18930950 PMID:25748550 PMID:35537566 |
|
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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|
G |
Cdkn2c |
cyclin-dependent kinase inhibitor 2C |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CDKN2C mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 5:124,411,123...124,416,278
Ensembl chr 5:124,411,124...124,416,278
|
|
G |
Cdkn2d |
cyclin dependent kinase inhibitor 2D |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CDKN2D mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 8:19,831,874...19,834,640
Ensembl chr 8:19,831,866...19,834,674
|
|
G |
Cdkn3 |
cyclin-dependent kinase inhibitor 3 |
decreases expression |
EXP ISO |
trovafloxacin results in decreased expression of CDKN3 mRNA |
CTD |
PMID:24136188 PMID:35537566 |
|
NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945
|
|
G |
Cdo1 |
cysteine dioxygenase type 1 |
increases expression |
ISO |
trovafloxacin results in increased expression of CDO1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr18:39,432,473...39,447,253
Ensembl chr18:39,432,474...39,447,296
|
|
G |
Cdon |
cell adhesion associated, oncogene regulated |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CDON mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 8:33,775,123...33,861,635
Ensembl chr 8:33,806,183...33,859,033
|
|
G |
Cdsn |
corneodesmosin |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CDSN mRNA |
CTD |
PMID:35537566 |
|
NCBI chr20:3,179,432...3,184,252
Ensembl chr20:3,179,438...3,184,250
|
|
G |
Cebpa |
CCAAT/enhancer binding protein alpha |
multiple interactions |
ISO |
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of CEBPA mRNA |
CTD |
PMID:18930950 |
|
NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
|
|
G |
Cebpg |
CCAAT/enhancer binding protein gamma |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CEBPG mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:87,683,060...87,692,772
Ensembl chr 1:87,684,019...87,694,569
|
|
G |
Celf6 |
CUGBP, Elav-like family member 6 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CELF6 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 8:59,975,095...60,006,060
Ensembl chr 8:59,975,088...60,005,041
|
|
G |
Cenatac |
centrosomal AT-AC splicing factor |
increases expression |
ISO |
trovafloxacin results in increased expression of CENATAC mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 8:44,735,968...44,742,859
Ensembl chr 8:44,735,972...44,742,837
|
|
G |
Cenpa |
centromere protein A |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CENPA mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 6:25,700,142...25,711,767
Ensembl chr 6:25,700,142...25,711,675
|
|
G |
Cenpe |
centromere protein E |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CENPE mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 2:223,637,035...223,695,692
Ensembl chr 2:223,636,998...223,695,669
|
|
G |
Cenpf |
centromere protein F |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CENPF mRNA |
CTD |
PMID:35537566 |
|
NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669
|
|
G |
Cenpi |
centromere protein I |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CENPI mRNA |
CTD |
PMID:35537566 |
|
NCBI chr X:97,515,919...97,567,671
Ensembl chr X:97,515,972...97,567,657
|
|
G |
Cenpk |
centromere protein K |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CENPK mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 2:35,360,390...35,421,372
Ensembl chr 2:35,360,132...35,385,706
|
|
G |
Cenpl |
centromere protein L |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CENPL mRNA |
CTD |
PMID:35537566 |
|
NCBI chr13:73,337,235...73,352,115
Ensembl chr13:73,337,257...73,352,114
|
|
G |
Cenpm |
centromere protein M |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CENPM mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 7:113,748,026...113,759,296
Ensembl chr 7:113,747,516...113,764,258
|
|
G |
Cenpn |
centromere protein N |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CENPN mRNA |
CTD |
PMID:35537566 |
|
NCBI chr19:44,971,265...44,994,019
Ensembl chr19:44,968,308...44,994,012
|
|
G |
Cenpp |
centromere protein P |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CENPP mRNA |
CTD |
PMID:35537566 |
|
NCBI chr17:15,014,087...15,189,312
Ensembl chr17:15,014,058...15,189,304
|
|
G |
Cenpq |
centromere protein Q |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CENPQ mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 9:19,957,122...19,972,807
Ensembl chr 9:19,957,048...19,972,789
|
|
G |
Cenpu |
centromere protein U |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CENPU mRNA |
CTD |
PMID:35537566 |
|
NCBI chr16:45,715,821...45,739,038
Ensembl chr16:45,714,294...45,738,823
|
|
G |
Cep128 |
centrosomal protein 128 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CEP128 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 6:109,951,009...110,328,686
Ensembl chr 6:109,951,061...110,328,713
|
|
G |
Cep131 |
centrosomal protein 131 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CEP131 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:105,346,015...105,370,380
Ensembl chr10:105,346,015...105,370,380
|
|
G |
Cep162 |
centrosomal protein 162 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CEP162 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 8:88,149,726...88,208,249
Ensembl chr 8:88,149,726...88,206,830
|
|
G |
Cep192 |
centrosomal protein 192 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CEP192 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr18:61,373,937...61,458,405
Ensembl chr18:61,332,158...61,458,379
|
|
G |
Cep290 |
centrosomal protein 290 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CEP290 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 7:35,310,071...35,399,388
Ensembl chr 7:35,310,199...35,399,392
|
|
G |
Cep55 |
centrosomal protein 55 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CEP55 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:235,832,823...235,848,401
Ensembl chr 1:235,832,878...235,848,394
|
|
G |
Cep57l1 |
centrosomal protein 57-like 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CEP57L1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr20:45,238,039...45,294,575
Ensembl chr20:45,238,044...45,294,540
|
|
G |
Cep72 |
centrosomal protein 72 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CEP72 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:29,225,312...29,255,294
Ensembl chr 1:29,225,361...29,255,271
|
|
G |
Cep78 |
centrosomal protein 78 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CEP78 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:213,246,183...213,275,275
Ensembl chr 1:213,246,187...213,275,181
|
|
G |
Cep83 |
centrosomal protein 83 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CEP83 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 7:29,280,358...29,389,574
Ensembl chr 7:29,280,419...29,389,574
|
|
G |
Cerkl |
ceramide kinase-like |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CERKL mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 3:64,238,714...64,344,695
Ensembl chr 3:64,237,522...64,340,675
|
|
G |
Cfl2 |
cofilin 2 |
increases expression |
ISO |
trovafloxacin results in increased expression of CFL2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 6:72,355,664...72,359,709
Ensembl chr 6:72,355,664...72,359,674
|
|
G |
Chac1 |
ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CHAC1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526
|
|
G |
Chadl |
chondroadherin-like |
increases expression |
ISO |
trovafloxacin results in increased expression of CHADL mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 7:113,205,323...113,218,678
Ensembl chr 7:113,210,748...113,217,272
|
|
G |
Chd5 |
chromodomain helicase DNA binding protein 5 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CHD5 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 5:162,848,273...162,898,997
Ensembl chr 5:162,848,394...162,896,291
|
|
G |
Chfr |
checkpoint with forkhead and ring finger domains |
multiple interactions |
ISO |
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of CHFR mRNA |
CTD |
PMID:18930950 |
|
NCBI chr12:46,504,497...46,538,104
Ensembl chr12:46,504,497...46,538,014
|
|
G |
Chka |
choline kinase alpha |
multiple interactions |
ISO |
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of CHKA mRNA |
CTD |
PMID:18930950 |
|
NCBI chr 1:201,076,804...201,125,517
Ensembl chr 1:201,076,860...201,125,516
|
|
G |
Chpf |
chondroitin polymerizing factor |
increases expression |
ISO |
trovafloxacin results in increased expression of CHPF mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 9:76,963,178...76,967,878
Ensembl chr 9:76,963,184...76,967,878
|
|
G |
Chst1 |
carbohydrate sulfotransferase 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CHST1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 3:78,552,059...78,574,740
Ensembl chr 3:78,548,525...78,574,883
|
|
G |
Chst7 |
carbohydrate sulfotransferase 7 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CHST7 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr X:2,396,260...2,432,828
Ensembl chr X:2,393,874...2,432,840
|
|
G |
Chtf18 |
chromosome transmission fidelity factor 18 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CHTF18 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:14,743,006...14,751,044
Ensembl chr10:14,742,621...14,751,050
|
|
G |
Cib2 |
calcium and integrin binding family member 2 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CIB2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 8:54,930,265...54,947,157
|
|
G |
Cip2a |
cellular inhibitor of PP2A |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CIP2A mRNA |
CTD |
PMID:35537566 |
|
NCBI chr11:51,792,143...51,823,016
Ensembl chr11:51,795,024...51,822,938
|
|
G |
Cit |
citron rho-interacting serine/threonine kinase |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CIT mRNA |
CTD |
PMID:35537566 |
|
NCBI chr12:40,603,073...40,764,846
Ensembl chr12:40,605,563...40,763,860
|
|
G |
Ckap2 |
cytoskeleton associated protein 2 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CKAP2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr16:69,839,668...69,864,852
Ensembl chr16:69,839,630...69,864,913
|
|
G |
Ckap2l |
cytoskeleton associated protein 2-like |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CKAP2L mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 3:116,497,186...116,524,302
Ensembl chr 3:116,498,022...116,524,366
|
|
G |
Ckap5 |
cytoskeleton associated protein 5 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CKAP5 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 3:77,491,195...77,593,300
Ensembl chr 3:77,491,276...77,593,264
|
|
G |
Cks2 |
CDC28 protein kinase regulatory subunit 2 |
decreases expression |
EXP |
trovafloxacin results in decreased expression of CKS2 mRNA |
CTD |
PMID:24136188 |
|
NCBI chr17:13,570,611...13,575,770
|
|
G |
Clcn5 |
chloride voltage-gated channel 5 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CLCN5 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr X:15,185,380...15,339,977
Ensembl chr X:15,185,451...15,334,264
|
|
G |
Cldn11 |
claudin 11 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CLDN11 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 2:112,207,745...112,221,050
Ensembl chr 2:112,207,745...112,221,050
|
|
G |
Cldn14 |
claudin 14 |
multiple interactions |
ISO |
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of CLDN14 mRNA |
CTD |
PMID:18930950 |
|
NCBI chr11:33,232,281...33,329,440
Ensembl chr11:33,232,220...33,329,171
|
|
G |
Clec2l |
C-type lectin domain family 2, member L |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CLEC2L mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 4:67,392,118...67,414,539
Ensembl chr 4:67,397,873...67,414,537
|
|
G |
Clec4a1 |
C-type lectin domain family 4, member A1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CLEC4A1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 4:156,173,894...156,186,009
Ensembl chr 4:156,173,894...156,186,008
|
|
G |
Clec7a |
C-type lectin domain containing 7A |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CLEC7A mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 4:162,902,731...162,913,931
Ensembl chr 4:162,902,732...162,913,897
|
|
G |
Clint1 |
clathrin interactor 1 |
multiple interactions |
ISO |
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of CLINT1 mRNA |
CTD |
PMID:18930950 |
|
NCBI chr10:30,298,618...30,353,185
Ensembl chr10:30,298,704...30,353,063
|
|
G |
Clip2 |
CAP-GLY domain containing linker protein 2 |
increases expression |
ISO |
trovafloxacin results in increased expression of CLIP2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr12:22,163,044...22,227,023
Ensembl chr12:22,163,218...22,227,023
|
|
G |
Clk1 |
CDC-like kinase 1 |
increases expression |
ISO |
trovafloxacin results in increased expression of CLK1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 9:59,947,774...59,959,002
Ensembl chr 9:59,947,764...59,957,000
|
|
G |
Cln6 |
CLN6, transmembrane ER protein |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CLN6 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 8:63,303,356...63,318,360
Ensembl chr 8:63,303,029...63,318,360
|
|
G |
Clspn |
claspin |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CLSPN mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 5:138,850,119...138,885,037
Ensembl chr 5:138,850,128...138,885,034
|
|
G |
Cmah |
cytidine monophospho-N-acetylneuraminic acid hydroxylase |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CMAH mRNA |
CTD |
PMID:35537566 |
|
NCBI chr17:40,557,161...40,642,350
Ensembl chr17:40,583,667...40,642,275
|
|
G |
Cmbl |
carboxymethylenebutenolidase homolog |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CMBL mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 2:82,569,257...82,591,007
Ensembl chr 2:82,571,888...82,591,009
|
|
G |
Cmpk2 |
cytidine/uridine monophosphate kinase 2 |
increases expression |
ISO |
trovafloxacin results in increased expression of CMPK2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 6:43,073,706...43,085,183
Ensembl chr 6:43,073,796...43,085,183
|
|
G |
Cntln |
centlein |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CNTLN mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 5:99,295,865...99,576,402
Ensembl chr 5:99,296,000...99,576,396
|
|
G |
Cntrl |
centriolin |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CNTRL mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 3:18,428,147...18,500,362
Ensembl chr 3:18,428,103...18,500,380
|
|
G |
Cntrob |
centrobin, centriole duplication and spindle assembly protein |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CNTROB mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:54,022,523...54,047,793
Ensembl chr10:54,022,852...54,044,849
|
|
G |
Coasy |
Coenzyme A synthase |
decreases expression |
ISO |
trovafloxacin results in decreased expression of COASY mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:86,014,566...86,018,849
Ensembl chr10:86,014,597...86,018,841
|
|
G |
Col14a1 |
collagen type XIV alpha 1 chain |
decreases expression |
ISO |
trovafloxacin results in decreased expression of COL14A1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 7:86,722,093...86,937,215
Ensembl chr 7:86,722,094...86,937,214
|
|
G |
Col15a1 |
collagen type XV alpha 1 chain |
decreases expression |
ISO |
trovafloxacin results in decreased expression of COL15A1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 5:61,501,963...61,607,591
Ensembl chr 5:61,501,963...61,607,591
|
|
G |
Comt |
catechol-O-methyltransferase |
multiple interactions |
ISO |
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of COMT mRNA |
CTD |
PMID:18930950 |
|
NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
|
|
G |
Copg1 |
COPI coat complex subunit gamma 1 |
decreases expression |
EXP |
trovafloxacin results in decreased expression of COPG1 mRNA |
CTD |
PMID:24136188 |
|
NCBI chr 4:120,366,540...120,392,502
Ensembl chr 4:120,366,542...120,415,616
|
|
G |
Cops9 |
COP9 signalosome subunit 9 |
increases expression |
ISO |
trovafloxacin results in increased expression of MYEOV2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 9:93,209,843...93,214,774
Ensembl chr 9:93,209,843...93,213,317
|
|
G |
Coq10a |
coenzyme Q10A |
decreases expression |
ISO |
trovafloxacin results in decreased expression of COQ10A mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 7:792,089...798,392
Ensembl chr 7:792,089...800,161
|
|
G |
Coq2 |
coenzyme Q2, polyprenyltransferase |
decreases expression |
ISO |
trovafloxacin results in decreased expression of COQ2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr14:8,941,429...8,961,418
Ensembl chr14:8,941,461...8,960,891
|
|
G |
Coro1b |
coronin 1B |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CORO1B mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:201,442,977...201,448,416
Ensembl chr 1:201,443,014...201,448,416
|
|
G |
Coro6 |
coronin 6 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CORO6 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:62,311,552...62,319,659
Ensembl chr10:62,311,660...62,319,659
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G |
Coro7 |
coronin 7 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CORO7 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:10,880,299...10,941,001
Ensembl chr10:10,885,196...10,941,001
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G |
Cox4i2 |
cytochrome c oxidase subunit 4i2 |
increases expression |
ISO |
trovafloxacin results in increased expression of COX4I2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 3:141,228,443...141,239,337
Ensembl chr 3:141,228,443...141,239,331
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|
G |
Cox6a2 |
cytochrome c oxidase subunit 6A2 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of COX6A2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:182,788,528...182,790,746
Ensembl chr 1:182,788,528...182,789,274
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|
G |
Cpe |
carboxypeptidase E |
increases expression |
ISO |
trovafloxacin results in increased expression of CPE mRNA |
CTD |
PMID:35537566 |
|
NCBI chr16:25,030,276...25,142,231
Ensembl chr16:25,030,276...25,142,233
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|
G |
Cpeb4 |
cytoplasmic polyadenylation element binding protein 4 |
increases expression |
ISO |
trovafloxacin results in increased expression of CPEB4 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:15,717,794...15,780,482
Ensembl chr10:15,717,794...15,780,603
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G |
Cped1 |
cadherin-like and PC-esterase domain containing 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CPED1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 4:50,516,712...50,789,651
Ensembl chr 4:50,516,819...50,788,674
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G |
Cpox |
coproporphyrinogen oxidase |
decreases expression |
EXP |
trovafloxacin results in decreased expression of CPOX mRNA |
CTD |
PMID:24136188 |
|
NCBI chr11:41,936,585...41,946,568
Ensembl chr11:41,936,591...41,946,746
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G |
Cpsf1 |
cleavage and polyadenylation specific factor 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CPSF1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 7:108,319,429...108,330,018
Ensembl chr 7:108,319,434...108,329,934
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|
G |
Cpt1a |
carnitine palmitoyltransferase 1A |
increases expression |
EXP |
trovafloxacin results in increased expression of CPT1A mRNA |
CTD |
PMID:24136188 |
|
NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
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|
G |
Cradd |
CASP2 and RIPK1 domain containing adaptor with death domain |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CRADD mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 7:29,940,240...29,952,907
Ensembl chr 7:29,798,586...29,952,907
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|
G |
Crebzf |
CREB/ATF bZIP transcription factor |
increases expression |
ISO |
trovafloxacin results in increased expression of CREBZF mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:144,416,864...144,423,540
Ensembl chr 1:144,417,446...144,428,553
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|
G |
Crk |
CRK proto-oncogene, adaptor protein |
multiple interactions |
ISO |
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of CRK mRNA |
CTD |
PMID:18930950 |
|
NCBI chr10:60,530,469...60,556,703
Ensembl chr10:60,530,464...60,553,406
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G |
Cryzl1 |
crystallin zeta like 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CRYZL1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr11:30,933,140...30,977,936
Ensembl chr11:30,933,144...30,977,867
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|
G |
Cs |
citrate synthase |
decreases expression |
EXP |
trovafloxacin results in decreased expression of CS mRNA |
CTD |
PMID:24136188 |
|
NCBI chr 7:758,074...791,421
Ensembl chr 7:758,345...791,421
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|
G |
Csad |
cysteine sulfinic acid decarboxylase |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CSAD mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 7:133,308,571...133,337,914
Ensembl chr 7:133,308,574...133,337,615
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|
G |
Csrnp1 |
cysteine and serine rich nuclear protein 1 |
increases expression |
ISO |
trovafloxacin results in increased expression of CSRNP1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 8:119,704,712...119,717,767
Ensembl chr 8:119,704,713...119,718,183
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|
G |
Cst7 |
cystatin F |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CST7 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 3:139,396,830...139,405,557
Ensembl chr 3:139,396,850...139,405,557
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|
G |
Cstf2t |
cleavage stimulation factor subunit 2, tau variant |
increases expression |
ISO |
trovafloxacin results in increased expression of CSTF2T mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:228,952,617...228,956,183
Ensembl chr 1:228,952,504...228,955,873
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|
G |
Ctdsp1 |
CTD small phosphatase 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CTDSP1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 9:75,973,694...75,979,298
Ensembl chr 9:75,973,962...75,979,297
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|
G |
Cth |
cystathionine gamma-lyase |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CTH mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234
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|
G |
Ctsc |
cathepsin C |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CTSC mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:142,028,386...142,059,841
Ensembl chr 1:142,028,392...142,060,387
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|
G |
Ctse |
cathepsin E |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CTSE mRNA |
CTD |
PMID:35537566 |
|
NCBI chr13:43,091,954...43,114,509
Ensembl chr13:43,092,128...43,114,502
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|
G |
Ctsf |
cathepsin F |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CTSF mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:202,152,777...202,158,525
Ensembl chr 1:202,152,728...202,158,525
|
|
G |
Cttnbp2nl |
CTTNBP2 N-terminal like |
increases expression |
ISO |
trovafloxacin results in increased expression of CTTNBP2NL mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 2:192,507,963...192,554,548
Ensembl chr 2:192,507,963...192,541,101
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|
G |
Cutc |
cutC copper transporter |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CUTC mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:242,622,281...242,637,048
Ensembl chr 1:242,622,276...242,637,047
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|
G |
Cux2 |
cut-like homeobox 2 |
increases expression |
ISO |
trovafloxacin results in increased expression of CUX2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr12:34,507,723...34,707,581
Ensembl chr12:34,520,959...34,705,806
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|
G |
Cxcl2 |
C-X-C motif chemokine ligand 2 |
multiple interactions increases expression |
ISO |
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of CXCL2 mRNA; trovafloxacin promotes the reaction [TNF protein results in increased expression of CXCL2 protein] trovafloxacin results in increased expression of CXCL2 mRNA |
CTD |
PMID:18930950 PMID:19638433 PMID:35537566 |
|
NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
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|
G |
Cxcl3 |
C-X-C motif chemokine ligand 3 |
multiple interactions |
ISO |
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of CXCL3 mRNA; trovafloxacin promotes the reaction [TNF protein results in increased expression of CXCL1 protein] |
CTD |
PMID:18930950 PMID:19638433 |
|
NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
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|
G |
Cyb5a |
cytochrome b5 type A |
increases expression |
ISO |
trovafloxacin results in increased expression of CYB5A mRNA |
CTD |
PMID:35537566 |
|
NCBI chr18:78,213,067...78,245,677
Ensembl chr18:78,202,342...78,258,535 Ensembl chr18:78,202,342...78,258,535
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|
G |
Cyb5d1 |
cytochrome b5 domain containing 1 |
increases expression |
ISO |
trovafloxacin results in increased expression of CYB5D1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:54,113,428...54,117,744
Ensembl chr10:54,113,438...54,117,911
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|
G |
Cyb5rl |
cytochrome b5 reductase-like |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CYB5RL mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 5:121,846,223...121,868,287
Ensembl chr 5:121,847,952...121,868,745
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|
G |
Cyfip2 |
cytoplasmic FMR1 interacting protein 2 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CYFIP2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:30,621,318...30,741,113
Ensembl chr10:30,621,318...30,741,113
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|
G |
Cyp19a1 |
cytochrome P450, family 19, subfamily a, polypeptide 1 |
decreases activity |
ISO |
trovafloxacin results in decreased activity of CYP19A1 protein |
CTD |
PMID:26141389 |
|
NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758
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|
G |
Cyp27a1 |
cytochrome P450, family 27, subfamily a, polypeptide 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CYP27A1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
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|
G |
Cyp2b12 |
cytochrome P450, family 2, subfamily b, polypeptide 12 |
decreases expression |
EXP |
trovafloxacin results in decreased expression of CYP2B12 mRNA |
CTD |
PMID:24136188 |
|
NCBI chr 1:82,007,609...82,019,409
Ensembl chr 1:82,007,609...82,080,480
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|
G |
Cyp2u1 |
cytochrome P450, family 2, subfamily u, polypeptide 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CYP2U1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 2:219,849,403...219,866,959
Ensembl chr 2:219,849,407...219,866,882
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|
G |
Cyp4f39 |
cytochrome P450, family 4, subfamily f, polypeptide 39 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CYP4F39 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 7:11,426,806...11,505,553
Ensembl chr 7:11,433,371...11,536,181
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|
G |
Cyp7a1 |
cytochrome P450 family 7 subfamily A member 1 |
multiple interactions |
ISO |
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of CYP7A1 mRNA |
CTD |
PMID:18930950 |
|
NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
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|
G |
Cyp8b1 |
cytochrome P450 family 8 subfamily B member 1 |
increases expression |
EXP |
trovafloxacin results in increased expression of CYP8B1 mRNA |
CTD |
PMID:24136188 |
|
NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166
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|
G |
Cyren |
cell cycle regulator of NHEJ |
decreases expression |
ISO |
trovafloxacin results in decreased expression of CYREN mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 4:63,547,311...63,553,394
Ensembl chr 4:63,547,335...63,551,602
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|
G |
Cyth4 |
cytohesin 4 |
increases expression |
ISO |
trovafloxacin results in increased expression of CYTH4 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 7:110,152,232...110,176,726
Ensembl chr 7:110,152,272...110,176,741
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|
G |
Dancr |
differentiation antagonizing non-protein coding RNA |
increases expression |
ISO |
trovafloxacin results in increased expression of DANCR mRNA |
CTD |
PMID:35537566 |
|
NCBI chr14:34,126,956...34,127,936
|
|
G |
Dapk1 |
death associated protein kinase 1 |
decreases expression |
EXP |
trovafloxacin results in decreased expression of DAPK1 mRNA |
CTD |
PMID:24136188 |
|
NCBI chr17:3,930,223...4,090,991
Ensembl chr17:3,930,213...4,090,991
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|
G |
Dars2 |
aspartyl-tRNA synthetase 2 (mitochondrial) |
decreases expression |
ISO |
trovafloxacin results in decreased expression of DARS2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr13:73,308,726...73,336,558
Ensembl chr13:73,308,726...73,336,934
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|
G |
Daxx |
death-domain associated protein |
increases expression |
ISO |
trovafloxacin results in increased expression of DAXX mRNA |
CTD |
PMID:35537566 |
|
NCBI chr20:4,970,090...4,976,145
Ensembl chr20:4,970,092...4,975,843
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|
G |
Dbf4 |
DBF4-CDC7 kinase regulatory subunit |
decreases expression |
ISO |
trovafloxacin results in decreased expression of DBF4 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 4:25,676,570...25,701,152
Ensembl chr 4:25,676,634...25,701,066
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|
G |
Dcp1b |
decapping mRNA 1B |
decreases expression |
ISO |
trovafloxacin results in decreased expression of DCP1B mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 4:152,358,267...152,395,747
Ensembl chr 4:152,358,241...152,397,145
|
|
G |
Ddit3 |
DNA-damage inducible transcript 3 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of DDIT3 mRNA |
CTD |
PMID:24136188 PMID:35537566 |
|
NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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|
G |
Ddx1 |
DEAD-box helicase 1 |
decreases expression |
EXP |
trovafloxacin results in decreased expression of DDX1 mRNA |
CTD |
PMID:24136188 |
|
NCBI chr 6:35,996,469...36,027,340
Ensembl chr 6:35,996,469...36,027,365
|
|
G |
Ddx17 |
DEAD-box helicase 17 |
multiple interactions |
ISO |
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of DDX17 mRNA |
CTD |
PMID:18930950 |
|
NCBI chr 7:111,091,127...111,109,353
Ensembl chr 7:111,089,445...111,109,193
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|
G |
Ddx23 |
DEAD-box helicase 23 |
increases expression |
ISO |
trovafloxacin results in increased expression of DDX23 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 7:129,797,620...129,814,909
Ensembl chr 7:129,797,614...129,814,949
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|
G |
Ddx59 |
DEAD-box helicase 59 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of DDX59 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr13:47,876,258...47,901,214
Ensembl chr13:47,876,261...47,901,214
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|
G |
Ddx6 |
DEAD-box helicase 6 |
increases expression |
ISO |
trovafloxacin results in increased expression of DDX6 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 8:44,931,127...44,967,773
Ensembl chr 8:44,931,974...44,964,405
|
|
G |
Ddx60 |
DEXD/H-box helicase 60 |
increases expression |
ISO |
trovafloxacin results in increased expression of DDX60 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr16:28,077,000...28,197,903
Ensembl chr16:28,076,999...28,179,526
|
|
G |
Dek |
DEK proto-oncogene |
decreases expression |
ISO |
trovafloxacin results in decreased expression of DEK mRNA |
CTD |
PMID:35537566 |
|
NCBI chr17:17,580,804...17,602,825
Ensembl chr17:17,580,843...17,602,808
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|
G |
Dennd2d |
DENN domain containing 2D |
decreases expression |
ISO |
trovafloxacin results in decreased expression of DENND2D mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 2:193,973,231...193,992,275
Ensembl chr 2:193,973,231...193,992,270
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|
G |
Dennd4a |
DENN domain containing 4A |
decreases expression |
ISO |
trovafloxacin results in decreased expression of DENND4A mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 8:65,322,920...65,436,331
Ensembl chr 8:65,322,941...65,436,330
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|
G |
Dennd5b |
DENN domain containing 5B |
increases expression |
ISO |
trovafloxacin results in increased expression of DENND5B mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 4:181,959,597...182,089,661
Ensembl chr 4:181,961,386...182,089,362
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|
G |
Depdc1 |
DEP domain containing 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of DEPDC1A mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 2:248,684,508...248,717,951
Ensembl chr 2:248,684,523...248,717,951
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|
G |
Depdc1b |
DEP domain containing 1B |
decreases expression |
ISO |
trovafloxacin results in decreased expression of DEPDC1B mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 2:39,891,163...39,963,779
Ensembl chr 2:39,891,481...39,963,779
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|
G |
Depdc7 |
DEP domain containing 7 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of DEPDC7 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 3:91,099,111...91,121,152
Ensembl chr 3:91,099,835...91,121,124
|
|
G |
Deptor |
DEP domain containing MTOR-interacting protein |
decreases expression |
ISO |
trovafloxacin results in decreased expression of DEPTOR mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 7:86,514,859...86,668,817
Ensembl chr 7:86,514,988...86,667,773
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|
G |
Derl2 |
derlin 2 |
multiple interactions |
ISO |
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of DERL2 mRNA |
CTD |
PMID:18930950 |
|
NCBI chr10:55,727,764...55,739,442
Ensembl chr10:55,727,643...55,739,518
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|
G |
Det1 |
DET1 partner of COP1 E3 ubiquitin ligase |
decreases expression |
ISO |
trovafloxacin results in decreased expression of DET1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:132,749,736...132,765,963
Ensembl chr 1:132,749,756...132,765,923
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|
G |
Dffb |
DNA fragmentation factor subunit beta |
increases expression |
ISO |
trovafloxacin results in increased expression of DFFB mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 5:164,522,446...164,534,733
Ensembl chr 5:164,522,463...164,534,628
|
|
G |
Dgat2 |
diacylglycerol O-acyltransferase 2 |
decreases expression |
EXP ISO |
trovafloxacin results in decreased expression of DGAT2 mRNA |
CTD |
PMID:24136188 PMID:35537566 |
|
NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
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|
G |
Dgke |
diacylglycerol kinase epsilon |
increases expression |
ISO |
trovafloxacin results in increased expression of DGKE mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:73,853,030...73,877,334
Ensembl chr10:73,855,583...73,877,100
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|
G |
Dgkg |
diacylglycerol kinase, gamma |
decreases expression |
ISO |
trovafloxacin results in decreased expression of DGKG mRNA |
CTD |
PMID:35537566 |
|
NCBI chr11:78,384,212...78,579,158
Ensembl chr11:78,384,458...78,577,212
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|
G |
Dguok |
deoxyguanosine kinase |
decreases expression |
ISO |
trovafloxacin results in decreased expression of DGUOK mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 4:115,987,101...116,014,733
Ensembl chr 4:115,979,094...116,014,733
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|
G |
Dhrs3 |
dehydrogenase/reductase 3 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of DHRS3 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 5:156,747,939...156,782,420
Ensembl chr 5:156,747,962...156,782,417
|
|
G |
Dhrs4 |
dehydrogenase/reductase 4 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of DHRS4 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr15:28,966,544...28,978,135
Ensembl chr15:28,966,553...28,978,127
|
|
G |
Dhx58 |
DEXH-box helicase 58 |
increases expression |
ISO |
trovafloxacin results in increased expression of DHX58 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:85,620,352...85,631,776
Ensembl chr10:85,620,357...85,631,525
|
|
G |
Diaph3 |
diaphanous-related formin 3 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of DIAPH3 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr15:62,543,375...63,013,060
Ensembl chr15:62,543,375...63,012,975
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|
G |
Disp3 |
dispatched RND transporter family member 3 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of DISP3 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 5:158,672,015...158,720,806
Ensembl chr 5:158,672,015...158,720,806
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G |
Dixdc1 |
DIX domain containing 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of DIXDC1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 8:51,007,835...51,081,191
Ensembl chr 8:51,007,838...51,081,090
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G |
Dlgap5 |
DLG associated protein 5 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of DLGAP5 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr15:20,633,964...20,664,569
Ensembl chr15:20,633,966...20,664,518
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G |
Dlst |
dihydrolipoamide S-succinyltransferase |
decreases expression |
EXP |
trovafloxacin results in decreased expression of DLST mRNA |
CTD |
PMID:24136188 |
|
NCBI chr 6:104,758,511...104,783,296
Ensembl chr 6:104,758,631...104,783,296
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G |
Dmac1 |
distal membrane arm assembly component 1 |
increases expression |
ISO |
trovafloxacin results in increased expression of DMAC1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 5:89,241,173...89,243,793
Ensembl chr 5:89,242,661...89,243,757
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G |
Dmpk |
DM1 protein kinase |
increases expression |
ISO |
trovafloxacin results in increased expression of DMPK mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:78,730,255...78,740,585
Ensembl chr 1:78,730,275...78,740,593
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G |
Dnah17 |
dynein, axonemal, heavy chain 17 |
increases expression |
ISO |
trovafloxacin results in increased expression of DNAH17 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:103,244,144...103,364,953
Ensembl chr10:103,249,363...103,364,901
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G |
Dnajb2 |
DnaJ heat shock protein family (Hsp40) member B2 |
multiple interactions |
ISO |
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of DNAJB2 mRNA |
CTD |
PMID:18930950 |
|
NCBI chr 9:76,731,060...76,739,278
Ensembl chr 9:76,731,065...76,739,277
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G |
Dnase2 |
deoxyribonuclease 2, lysosomal |
decreases expression |
ISO |
trovafloxacin results in decreased expression of DNASE2A mRNA |
CTD |
PMID:35537566 |
|
NCBI chr19:23,244,656...23,247,376
Ensembl chr19:23,244,664...23,247,376
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G |
Dnd1 |
DND microRNA-mediated repression inhibitor 1 |
increases expression |
ISO |
trovafloxacin results in increased expression of DND1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr18:28,378,692...28,381,316
Ensembl chr18:28,378,692...28,381,316
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G |
Dnmt1 |
DNA methyltransferase 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of DNMT1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
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G |
Dnmt3l |
DNA methyltransferase 3 like |
decreases expression |
ISO |
trovafloxacin results in decreased expression of DNMT3L mRNA |
CTD |
PMID:35537566 |
|
NCBI chr20:10,614,933...10,629,337
Ensembl chr20:10,614,934...10,629,516
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G |
Dnph1 |
2'-deoxynucleoside 5'-phosphate N-hydrolase 1 |
decreases expression |
EXP |
trovafloxacin results in decreased expression of DNPH1 mRNA |
CTD |
PMID:24136188 |
|
NCBI chr 9:14,481,296...14,484,034
Ensembl chr 9:14,481,066...14,484,022
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G |
Dock11 |
dedicator of cytokinesis 11 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of DOCK11 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr X:115,131,720...115,314,854
Ensembl chr X:115,131,909...115,314,854
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G |
Dock2 |
dedicator of cytokinesis 2 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of DOCK2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:18,827,237...19,244,832
Ensembl chr10:18,827,239...19,244,808
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G |
Dock9 |
dedicator of cytokinesis 9 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of DOCK9 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr15:98,611,518...98,883,306
Ensembl chr15:98,618,084...98,883,153
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G |
Donson |
DNA replication fork stabilization factor DONSON |
decreases expression |
ISO |
trovafloxacin results in decreased expression of DONSON mRNA |
CTD |
PMID:35537566 |
|
NCBI chr11:30,919,834...30,933,150
Ensembl chr11:30,923,239...30,932,889
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G |
Dpf1 |
double PHD fingers 1 |
increases expression |
ISO |
trovafloxacin results in increased expression of DPF1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:84,602,212...84,615,954
Ensembl chr 1:84,602,336...84,615,950
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G |
Drc3 |
dynein regulatory complex subunit 3 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of DRC3 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:45,149,094...45,200,659
Ensembl chr10:45,157,354...45,199,369
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G |
Dscc1 |
DNA replication and sister chromatid cohesion 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of DSCC1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 7:86,482,588...86,498,212
Ensembl chr 7:86,482,588...86,498,212
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|
G |
Dsn1 |
DSN1 component of MIS12 kinetochore complex |
decreases expression |
ISO |
trovafloxacin results in decreased expression of DSN1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 3:145,652,741...145,668,025
Ensembl chr 3:145,652,737...145,665,856
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G |
Dtnb |
dystrobrevin, beta |
decreases expression |
ISO |
trovafloxacin results in decreased expression of DTNB mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 6:26,566,418...26,763,467
Ensembl chr 6:26,566,925...26,766,335
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G |
Dtnbp1 |
dystrobrevin binding protein 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of DTNBP1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr17:19,685,218...19,776,668
Ensembl chr17:19,685,215...19,776,661
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G |
Dtx1 |
deltex E3 ubiquitin ligase 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of DTX1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr12:35,849,647...35,880,835
Ensembl chr12:35,849,617...35,880,838
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G |
Dtymk |
deoxythymidylate kinase |
decreases expression |
EXP |
trovafloxacin results in decreased expression of DTYMK mRNA |
CTD |
PMID:24136188 |
|
NCBI chr 9:94,315,552...94,324,386
Ensembl chr 9:94,315,552...94,324,870
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G |
Dus1l |
dihydrouridine synthase 1-like |
decreases expression |
ISO |
trovafloxacin results in decreased expression of DUS1L mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:106,055,519...106,062,656
Ensembl chr10:106,055,519...106,062,781
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G |
Dus4l |
dihydrouridine synthase 4-like |
decreases expression |
ISO |
trovafloxacin results in decreased expression of DUS4L mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 6:48,228,111...48,242,553
Ensembl chr 6:48,228,111...48,242,449
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G |
Dusp1 |
dual specificity phosphatase 1 |
increases expression |
ISO |
trovafloxacin results in increased expression of DUSP1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:16,680,478...16,683,275
|
|
G |
Dusp16 |
dual specificity phosphatase 16 |
multiple interactions |
ISO |
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of DUSP16 mRNA |
CTD |
PMID:18930950 |
|
NCBI chr 4:167,546,780...167,630,173
Ensembl chr 4:167,548,155...167,629,980
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G |
Dusp2 |
dual specificity phosphatase 2 |
increases expression |
ISO |
trovafloxacin results in increased expression of DUSP2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 3:114,556,325...114,558,510
Ensembl chr 3:114,556,325...114,558,499
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G |
Dusp5 |
dual specificity phosphatase 5 |
increases expression |
ISO |
trovafloxacin results in increased expression of DUSP5 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818
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G |
Dusp8 |
dual specificity phosphatase 8 |
multiple interactions |
ISO |
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of DUSP8 mRNA |
CTD |
PMID:18930950 |
|
NCBI chr 1:197,167,392...197,184,285
Ensembl chr 1:197,169,422...197,182,921
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G |
Dut |
deoxyuridine triphosphatase |
decreases expression |
EXP ISO |
trovafloxacin results in decreased expression of DUT mRNA |
CTD |
PMID:24136188 PMID:35537566 |
|
NCBI chr 3:112,498,864...112,509,994
Ensembl chr 3:112,498,982...112,510,771
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G |
Dym |
dymeclin |
decreases expression |
ISO |
trovafloxacin results in decreased expression of DYM mRNA |
CTD |
PMID:35537566 |
|
NCBI chr18:68,605,131...68,900,905
Ensembl chr18:68,605,185...68,900,903
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G |
Dync2i2 |
dynein 2 intermediate chain 2 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of DYNC2I2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 3:13,306,039...13,322,121
Ensembl chr 3:13,306,039...13,322,121
|
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G |
Dyrk1b |
dual specificity tyrosine phosphorylation regulated kinase 1B |
increases expression |
ISO |
trovafloxacin results in increased expression of DYRK1B mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:83,479,168...83,497,011
Ensembl chr 1:83,479,147...83,487,169
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G |
Dyrk3 |
dual specificity tyrosine phosphorylation regulated kinase 3 |
increases expression |
ISO |
trovafloxacin results in increased expression of DYRK3 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr13:42,594,120...42,604,898
Ensembl chr13:42,594,121...42,604,778
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G |
Dzip3 |
DAZ interacting zinc finger protein 3 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of DZIP3 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr11:51,823,235...51,893,353
Ensembl chr11:51,823,231...51,893,353
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|
G |
E2f1 |
E2F transcription factor 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of E2F1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361
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G |
E2f7 |
E2F transcription factor 7 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of E2F7 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 7:46,150,533...46,192,739
Ensembl chr 7:46,151,293...46,192,734
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|
G |
E2f8 |
E2F transcription factor 8 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of E2F8 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:98,565,717...98,584,265
Ensembl chr 1:98,565,717...98,584,098
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|
G |
Eaf1 |
ELL associated factor 1 |
increases expression |
ISO |
trovafloxacin results in increased expression of EAF1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr16:6,698,322...6,713,071
Ensembl chr16:6,698,322...6,713,071
|
|
G |
Ears2 |
glutamyl-tRNA synthetase 2, mitochondrial |
decreases expression |
ISO |
trovafloxacin results in decreased expression of EARS2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:176,597,986...176,625,848
Ensembl chr 1:176,597,986...176,625,836
|
|
G |
Echdc2 |
enoyl CoA hydratase domain containing 2 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ECHDC2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 5:122,915,874...122,934,860
Ensembl chr 5:122,916,134...122,934,859
|
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G |
Echdc3 |
enoyl CoA hydratase domain containing 3 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ECHDC3 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr17:72,070,697...72,093,519
Ensembl chr17:72,070,668...72,093,516
|
|
G |
Eci1 |
enoyl-CoA delta isomerase 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ECI1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:13,456,715...13,470,061
Ensembl chr10:13,456,563...13,470,061
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|
G |
Ect2 |
epithelial cell transforming 2 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ECT2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 2:109,975,813...110,037,911
Ensembl chr 2:109,975,813...110,037,911
|
|
G |
Eda2r |
ectodysplasin A2 receptor |
increases expression |
ISO |
trovafloxacin results in increased expression of EDA2R mRNA |
CTD |
PMID:35537566 |
|
NCBI chr X:62,224,763...62,269,333
Ensembl chr X:62,228,229...62,269,268
|
|
G |
Eef2k |
eukaryotic elongation factor-2 kinase |
decreases expression |
ISO |
trovafloxacin results in decreased expression of EEF2K mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:175,393,119...175,456,756
Ensembl chr 1:175,393,154...175,455,164
|
|
G |
Eef2kmt |
eukaryotic elongation factor 2 lysine methyltransferase |
decreases expression |
ISO |
trovafloxacin results in decreased expression of EEF2KMT mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:10,336,933...10,349,463
Ensembl chr10:10,336,974...10,347,039
|
|
G |
Efcab11 |
EF-hand calcium binding domain 11 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of EFCAB11 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 6:119,008,908...119,162,994
Ensembl chr 6:119,008,919...119,162,046
|
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G |
Efcab2 |
EF-hand calcium binding domain 2 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of EFCAB2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr13:90,152,002...90,237,918
Ensembl chr13:90,152,185...90,238,218
|
|
G |
Efcab5 |
EF-hand calcium binding domain 5 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of EFCAB5 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:61,926,419...62,042,745
Ensembl chr10:61,926,953...62,042,749
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G |
Efnb3 |
ephrin B3 |
increases expression |
ISO |
trovafloxacin results in increased expression of EFNB3 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:54,274,506...54,281,951
Ensembl chr10:54,274,506...54,280,471
|
|
G |
Egfl7 |
EGF-like-domain, multiple 7 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of EGFL7 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 3:9,404,622...9,416,879
Ensembl chr 3:9,407,520...9,416,879
|
|
G |
Egfr |
epidermal growth factor receptor |
multiple interactions |
ISO |
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of EGFR mRNA |
CTD |
PMID:18930950 |
|
NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
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|
G |
Egr3 |
early growth response 3 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of EGR3 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr15:45,150,335...45,156,052
Ensembl chr15:45,150,567...45,154,627
|
|
G |
Ei24 |
EI24, autophagy associated transmembrane protein |
increases expression |
ISO |
trovafloxacin results in increased expression of EI24 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 8:36,494,289...36,510,653
Ensembl chr 8:36,494,289...36,510,571
|
|
G |
Eid1 |
EP300 interacting inhibitor of differentiation 1 |
increases expression |
ISO |
trovafloxacin results in increased expression of EID1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 3:112,922,961...112,924,680
Ensembl chr 3:112,922,668...112,924,752
|
|
G |
Eid2b |
EP300 interacting inhibitor of differentiation 2B |
increases expression |
ISO |
trovafloxacin results in increased expression of EID2B mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:83,545,530...83,547,338
Ensembl chr 1:83,545,563...83,546,734
|
|
G |
Eif2ak2 |
eukaryotic translation initiation factor 2-alpha kinase 2 |
increases expression |
ISO |
trovafloxacin results in increased expression of EIF2AK2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 6:16,189,000...16,224,972
Ensembl chr 6:16,188,979...16,224,971
|
|
G |
Eif2b2 |
eukaryotic translation initiation factor 2B subunit beta |
decreases expression |
ISO |
trovafloxacin results in decreased expression of EIF2B2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 6:104,866,926...104,873,351
Ensembl chr 6:104,866,753...104,873,353
|
|
G |
Eif2s1 |
eukaryotic translation initiation factor 2 subunit alpha |
decreases expression |
EXP |
trovafloxacin results in decreased expression of EIF2S1 mRNA |
CTD |
PMID:24136188 |
|
NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
|
|
G |
Eif2s2 |
eukaryotic translation initiation factor 2 subunit beta |
multiple interactions |
ISO |
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of EIF2S2 mRNA |
CTD |
PMID:18930950 |
|
NCBI chr 3:143,374,652...143,395,460
Ensembl chr 3:143,373,686...143,395,432
|
|
G |
Eif3a |
eukaryotic translation initiation factor 3, subunit A |
multiple interactions |
ISO |
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of EIF3A mRNA |
CTD |
PMID:18930950 |
|
NCBI chr 1:259,902,767...259,932,976
Ensembl chr 1:259,902,680...259,932,976
|
|
G |
Eif3c |
eukaryotic translation initiation factor 3, subunit C |
decreases expression |
EXP |
trovafloxacin results in decreased expression of EIF3C mRNA |
CTD |
PMID:24136188 |
|
NCBI chr 1:181,134,604...181,152,489
Ensembl chr 1:181,134,604...181,152,493
|
|
G |
Eif3l |
eukaryotic translation initiation factor 3, subunit L |
decreases expression |
EXP |
trovafloxacin results in decreased expression of EIF3L mRNA |
CTD |
PMID:24136188 |
|
NCBI chr 7:110,652,565...110,663,614
Ensembl chr 7:110,627,107...110,663,614
|
|
G |
Eif4a2 |
eukaryotic translation initiation factor 4A2 |
increases expression |
EXP ISO |
trovafloxacin results in increased expression of EIF4A2 mRNA |
CTD |
PMID:24136188 PMID:35537566 |
|
NCBI chr11:77,764,126...77,770,810
Ensembl chr11:77,764,124...77,770,781
|
|
G |
Eif4ebp1 |
eukaryotic translation initiation factor 4E binding protein 1 |
multiple interactions decreases expression |
ISO |
[trovafloxacin co-treated with TNF protein] results in increased phosphorylation of EIF4EBP1 protein; Sirolimus inhibits the reaction [[trovafloxacin co-treated with TNF protein] results in increased phosphorylation of EIF4EBP1 protein] trovafloxacin results in decreased expression of EIF4EBP1 mRNA |
CTD |
PMID:33609687 PMID:35537566 |
|
NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
|
|
G |
Eif6 |
eukaryotic translation initiation factor 6 |
multiple interactions |
ISO |
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of EIF6 mRNA |
CTD |
PMID:18930950 |
|
NCBI chr 3:144,325,038...144,331,396
Ensembl chr 3:144,325,036...144,331,401
|
|
G |
Ell2 |
elongation factor for RNA polymerase II 2 |
increases expression |
ISO |
trovafloxacin results in increased expression of ELL2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 2:5,189,375...5,258,781
Ensembl chr 2:5,189,971...5,258,781
|
|
G |
Elmo3 |
engulfment and cell motility 3 |
increases expression |
ISO |
trovafloxacin results in increased expression of ELMO3 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr19:33,181,952...33,186,399
Ensembl chr19:33,182,036...33,186,410
|
|
G |
Elovl6 |
ELOVL fatty acid elongase 6 |
decreases expression |
EXP |
trovafloxacin results in decreased expression of ELOVL6 mRNA |
CTD |
PMID:24136188 |
|
NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186
|
|
G |
Emc1 |
ER membrane protein complex subunit 1 |
decreases expression |
EXP |
trovafloxacin results in decreased expression of EMC1 mRNA |
CTD |
PMID:24136188 |
|
NCBI chr 5:151,608,557...151,633,888
Ensembl chr 5:151,608,568...151,633,888
|
|
G |
Eme1 |
essential meiotic structure-specific endonuclease 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of EME1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:79,586,718...79,595,515
Ensembl chr10:79,586,729...79,595,435
|
|
G |
Eml6 |
EMAP like 6 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of EML6 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr14:103,471,537...103,806,120
Ensembl chr14:103,476,372...103,805,849
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G |
Endog |
endonuclease G |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ENDOG mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 3:13,449,113...13,451,715
Ensembl chr 3:13,449,086...13,451,932
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G |
Eno3 |
enolase 3 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ENO3 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:55,370,531...55,375,921
Ensembl chr10:55,366,975...55,375,921
|
|
G |
Enpp1 |
ectonucleotide pyrophosphatase/phosphodiesterase 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ENPP1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715
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|
G |
Enpp6 |
ectonucleotide pyrophosphatase/phosphodiesterase 6 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ENPP6 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr16:45,165,883...45,294,126
Ensembl chr16:45,169,178...45,294,077
|
|
G |
Entpd1 |
ectonucleoside triphosphate diphosphohydrolase 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ENTPD1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:239,425,515...239,552,323
Ensembl chr 1:239,425,430...239,552,317
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G |
Epha2 |
Eph receptor A2 |
increases expression |
ISO |
trovafloxacin results in increased expression of EPHA2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 5:153,605,644...153,634,115
Ensembl chr 5:153,605,644...153,634,117
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|
G |
Ephx1 |
epoxide hydrolase 1 |
decreases expression |
EXP |
trovafloxacin results in decreased expression of EPHX1 mRNA |
CTD |
PMID:24136188 |
|
NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235
|
|
G |
Epm2a |
EPM2A glucan phosphatase, laforin |
decreases expression |
ISO |
trovafloxacin results in decreased expression of EPM2A mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:5,727,111...5,845,338
Ensembl chr 1:5,727,066...5,920,555
|
|
G |
Epm2aip1 |
EPM2A interacting protein 1 |
increases expression |
ISO |
trovafloxacin results in increased expression of EPM2AIP1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 8:111,233,871...111,241,219
Ensembl chr 8:111,233,826...111,241,871
|
|
G |
Eprs1 |
glutamyl-prolyl-tRNA synthetase 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of EPRS1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr13:96,901,548...96,971,966
Ensembl chr13:96,901,575...96,971,966
|
|
G |
Ercc1 |
ERCC excision repair 1, endonuclease non-catalytic subunit |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ERCC1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963
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|
G |
Ercc6l |
ERCC excision repair 6 like, spindle assembly checkpoint helicase |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ERCC6L mRNA |
CTD |
PMID:35537566 |
|
NCBI chr X:67,245,414...67,261,222
Ensembl chr X:67,245,414...67,280,756
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|
G |
Ergic1 |
endoplasmic reticulum-golgi intermediate compartment 1 |
decreases expression |
EXP |
trovafloxacin results in decreased expression of ERGIC1 mRNA |
CTD |
PMID:24136188 |
|
NCBI chr10:16,531,192...16,626,974
Ensembl chr10:16,531,194...16,626,957
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|
G |
Ermp1 |
endoplasmic reticulum metallopeptidase 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ERMP1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:227,383,992...227,422,120
Ensembl chr 1:227,387,920...227,436,909
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|
G |
Erp29 |
endoplasmic reticulum protein 29 |
decreases expression |
EXP |
trovafloxacin results in decreased expression of ERP29 mRNA |
CTD |
PMID:24136188 |
|
NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376
|
|
G |
Errfi1 |
ERBB receptor feedback inhibitor 1 |
multiple interactions |
ISO |
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of ERRFI1 mRNA |
CTD |
PMID:18930950 |
|
NCBI chr 5:161,323,981...161,337,289
Ensembl chr 5:161,323,998...161,337,282
|
|
G |
Esco2 |
establishment of sister chromatid cohesion N-acetyltransferase 2 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ESCO2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr15:40,034,566...40,052,295
Ensembl chr15:40,034,568...40,055,306
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|
G |
Esd |
esterase D |
increases expression |
ISO |
trovafloxacin results in increased expression of ESD mRNA |
CTD |
PMID:35537566 |
|
NCBI chr15:50,043,634...50,063,134
Ensembl chr15:50,043,632...50,063,144
|
|
G |
Espl1 |
extra spindle pole bodies like 1, separase |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ESPL1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 7:133,424,027...133,450,984
Ensembl chr 7:133,424,130...133,450,984
|
|
G |
Esr1 |
estrogen receptor 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ESR1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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|
G |
Esyt1 |
extended synaptotagmin 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ESYT1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 7:928,848...946,199
Ensembl chr 7:928,848...946,199
|
|
G |
Esyt2 |
extended synaptotagmin 2 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of ESYT2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 6:137,219,653...137,312,590
Ensembl chr 6:137,219,707...137,312,590
|
|
G |
Ets2 |
ETS proto-oncogene 2, transcription factor |
multiple interactions |
ISO |
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of ETS2 mRNA |
CTD |
PMID:18930950 |
|
NCBI chr11:35,021,536...35,038,322
Ensembl chr11:35,021,596...35,038,319
|
|
G |
Etv3 |
ETS variant transcription factor 3 |
increases expression |
ISO |
trovafloxacin results in increased expression of ETV3 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 2:172,965,461...172,980,320
Ensembl chr 2:172,965,588...172,980,314
|
|
G |
Evi2a |
ecotropic viral integration site 2A |
increases expression |
ISO |
trovafloxacin results in increased expression of EVI2A mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:64,485,760...64,489,660
Ensembl chr10:64,485,200...64,489,843
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|
G |
Evi5 |
ecotropic viral integration site 5 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of EVI5 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr14:1,875,601...2,021,678
Ensembl chr14:1,875,647...2,021,678
|
|
G |
Exd2 |
exonuclease 3'-5' domain containing 2 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of EXD2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 6:100,116,867...100,150,452
Ensembl chr 6:100,116,867...100,150,442
|
|
G |
Extl1 |
exostosin-like glycosyltransferase 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of EXTL1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 5:146,573,911...146,589,115
Ensembl chr 5:146,573,912...146,589,115
|
|
G |
Eya4 |
EYA transcriptional coactivator and phosphatase 4 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of EYA4 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:22,172,275...22,415,978
Ensembl chr 1:22,172,275...22,415,976
|
|
G |
Ezh2 |
enhancer of zeste 2 polycomb repressive complex 2 subunit |
decreases expression |
ISO |
trovafloxacin results in decreased expression of EZH2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362
|
|
G |
F10 |
coagulation factor X |
decreases expression |
ISO |
trovafloxacin results in decreased expression of F10 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr16:76,468,834...76,488,141
Ensembl chr16:76,468,838...76,488,141
|
|
G |
F12 |
coagulation factor XII |
increases expression |
ISO |
trovafloxacin results in increased expression of F12 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530
|
|
G |
F2 |
coagulation factor II, thrombin |
multiple interactions |
ISO |
[Lipopolysaccharides co-treated with trovafloxacin] results in increased activity of F2 protein |
CTD |
PMID:19367693 |
|
NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
|
|
G |
F7 |
coagulation factor VII |
decreases expression |
ISO |
trovafloxacin results in decreased expression of F7 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr16:76,489,775...76,500,636
Ensembl chr16:76,489,717...76,500,610
|
|
G |
Faah |
fatty acid amide hydrolase |
decreases expression |
ISO |
trovafloxacin results in decreased expression of FAAH mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 5:129,479,774...129,499,018
Ensembl chr 5:129,479,824...129,498,677
|
|
G |
Faap100 |
FA core complex associated protein 100 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of FAAP100 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:105,641,677...105,653,809
Ensembl chr10:105,639,414...105,653,494
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|
G |
Faf1 |
Fas associated factor 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of FAF1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 5:124,426,032...124,790,014
Ensembl chr 5:124,426,062...124,789,977
|
|
G |
Fam120c |
family with sequence similarity 120 member C |
decreases expression |
ISO |
trovafloxacin results in decreased expression of FAM120C mRNA |
CTD |
PMID:35537566 |
|
NCBI chr X:20,324,046...20,477,831
Ensembl chr X:20,323,381...20,477,275
|
|
G |
Fam131a |
family with sequence similarity 131, member A |
decreases expression |
ISO |
trovafloxacin results in decreased expression of FAM131A mRNA |
CTD |
PMID:35537566 |
|
NCBI chr11:80,211,577...80,221,527
Ensembl chr11:80,211,745...80,221,511
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|
G |
Fam13c |
family with sequence similarity 13, member C |
decreases expression |
ISO |
trovafloxacin results in decreased expression of FAM13C mRNA |
CTD |
PMID:35537566 |
|
NCBI chr20:18,065,625...18,187,792
Ensembl chr20:18,065,628...18,187,592
|
|
G |
Fam171a2 |
family with sequence similarity 171, member A2 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of FAM171A2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:87,393,888...87,404,051
Ensembl chr10:87,394,007...87,404,053
|
|
G |
Fam171b |
family with sequence similarity 171, member B |
decreases expression |
ISO |
trovafloxacin results in decreased expression of FAM171B mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 3:68,930,755...68,986,113
Ensembl chr 3:68,930,822...68,986,127
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|
G |
Fam222b |
family with sequence similarity 222, member B |
increases expression |
ISO |
trovafloxacin results in increased expression of FAM222B mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:62,986,571...63,052,350
Ensembl chr10:62,986,571...63,052,350
|
|
G |
Fam83d |
family with sequence similarity 83, member D |
decreases expression |
ISO |
trovafloxacin results in decreased expression of FAM83D mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 3:147,421,941...147,441,211
Ensembl chr 3:147,421,908...147,441,192
|
|
G |
Fam83h |
family with sequence similarity 83, member H |
increases expression |
ISO |
trovafloxacin results in increased expression of FAM83H mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 7:107,716,431...107,724,619
Ensembl chr 7:107,716,431...107,728,672
|
|
G |
Fam98a |
family with sequence similarity 98, member A |
decreases expression |
EXP |
trovafloxacin results in decreased expression of FAM98A mRNA |
CTD |
PMID:24136188 |
|
NCBI chr 6:19,874,082...19,888,744
Ensembl chr 6:19,874,071...19,888,742
|
|
G |
Fanca |
FA complementation group A |
decreases expression |
ISO |
trovafloxacin results in decreased expression of FANCA mRNA |
CTD |
PMID:35537566 |
|
NCBI chr19:51,304,126...51,362,586
Ensembl chr19:51,304,021...51,362,527
|
|
G |
Fancb |
FA complementation group B |
decreases expression |
ISO |
trovafloxacin results in decreased expression of FANCB mRNA |
CTD |
PMID:35537566 |
|
NCBI chr X:29,403,771...29,420,484
Ensembl chr X:29,403,771...29,420,192
|
|
G |
Fancc |
FA complementation group C |
decreases expression |
ISO |
trovafloxacin results in decreased expression of FANCC mRNA |
CTD |
PMID:35537566 |
|
NCBI chr17:1,680,660...1,822,610
Ensembl chr17:1,681,324...1,829,376
|
|
G |
Fancd2 |
FA complementation group D2 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of FANCD2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 4:146,679,014...146,743,422
Ensembl chr 4:146,679,179...146,743,412
|
|
G |
Fanci |
FA complementation group I |
decreases expression |
ISO |
trovafloxacin results in decreased expression of FANCI mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:133,327,264...133,383,661
Ensembl chr 1:133,327,297...133,383,640
|
|
G |
Fasn |
fatty acid synthase |
multiple interactions decreases expression |
ISO EXP |
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of FASN mRNA trovafloxacin results in decreased expression of FASN mRNA |
CTD |
PMID:18930950 PMID:24136188 |
|
NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
|
|
G |
Fbxl12 |
F-box and leucine-rich repeat protein 12 |
increases expression |
ISO |
trovafloxacin results in increased expression of FBXL12 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 8:19,175,864...19,183,373
Ensembl chr 8:19,160,352...19,183,607
|
|
G |
Fbxo15 |
F-box protein 15 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of FBXO15 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr18:78,319,577...78,634,695
Ensembl chr18:78,319,534...78,390,765
|
|
G |
Fbxo33 |
F-box protein 33 |
increases expression |
ISO |
trovafloxacin results in increased expression of FBXO33 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 6:76,900,619...76,934,232
Ensembl chr 6:76,900,631...76,932,669
|
|
G |
Fbxo36 |
F-box protein 36 |
increases expression |
ISO |
trovafloxacin results in increased expression of FBXO36 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 9:86,042,522...86,107,220
Ensembl chr 9:86,040,862...86,107,229
|
|
G |
Fbxo48 |
F-box protein 48 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of FBXO48 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr14:91,380,857...91,382,314
Ensembl chr14:91,380,857...91,382,314
|
|
G |
Fbxo5 |
F-box protein 5 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of FBXO5 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:42,196,068...42,202,437
Ensembl chr 1:42,196,068...42,202,437
|
|
G |
Fbxo9 |
f-box protein 9 |
multiple interactions |
ISO |
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of FBXO9 mRNA |
CTD |
PMID:18930950 |
|
NCBI chr 8:78,958,482...78,984,015
Ensembl chr 8:78,958,483...78,983,949
|
|
G |
Fbxw10 |
F-box and WD repeat domain containing 10 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of FBXW10 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:47,513,313...47,551,909
Ensembl chr10:47,486,297...47,551,907
|
|
G |
Fcf1 |
Fcf1 rRNA-processing protein |
increases expression |
ISO |
trovafloxacin results in increased expression of FCF1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 6:104,617,780...104,629,643
Ensembl chr 6:104,617,770...104,629,643
|
|
G |
Fcgr2b |
Fc gamma receptor 2B |
decreases expression |
ISO |
trovafloxacin results in decreased expression of FCGR2B mRNA |
CTD |
PMID:35537566 |
|
NCBI chr13:83,191,253...83,207,778
Ensembl chr13:83,193,163...83,207,778
|
|
G |
Fchsd1 |
FCH and double SH3 domains 1 |
increases expression |
ISO |
trovafloxacin results in increased expression of FCHSD1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr18:29,793,899...29,804,533
Ensembl chr18:29,793,899...29,804,466
|
|
G |
Fdxr |
ferredoxin reductase |
decreases expression |
ISO |
trovafloxacin results in decreased expression of FDXR mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:100,507,863...100,516,649
Ensembl chr10:100,507,865...100,516,658
|
|
G |
Ffar4 |
free fatty acid receptor 4 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of FFAR4 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:235,873,576...235,891,597
Ensembl chr 1:235,873,576...235,891,597
|
|
G |
Fga |
fibrinogen alpha chain |
multiple interactions |
ISO |
[Lipopolysaccharides co-treated with trovafloxacin] results in increased expression of FGA protein |
CTD |
PMID:19367693 |
|
NCBI chr 2:168,374,120...168,381,523
Ensembl chr 2:168,374,120...168,381,528
|
|
G |
Fgd4 |
FYVE, RhoGEF and PH domain containing 4 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of FGD4 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr11:84,399,989...84,551,013
Ensembl chr11:84,399,816...84,546,972
|
|
G |
Fgf22 |
fibroblast growth factor 22 |
increases expression |
ISO |
trovafloxacin results in increased expression of FGF22 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 7:9,947,632...9,956,918
Ensembl chr 7:9,948,071...9,950,486
|
|
G |
Fignl2 |
fidgetin-like 2 |
increases expression |
ISO |
trovafloxacin results in increased expression of FIGNL2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 7:132,160,006...132,187,896
Ensembl chr 7:132,162,390...132,164,336
|
|
G |
Filip1l |
filamin A interacting protein 1-like |
decreases expression |
ISO |
trovafloxacin results in decreased expression of FILIP1L mRNA |
CTD |
PMID:35537566 |
|
NCBI chr11:42,937,353...43,177,085
Ensembl chr11:42,940,467...43,177,415
|
|
G |
Fkbp11 |
FKBP prolyl isomerase 11 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of FKBP11 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 7:129,871,870...129,877,760
Ensembl chr 7:129,871,870...129,875,303
|
|
G |
Fkbp15 |
FKBP prolyl isomerase family member 15 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of FKBP15 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 5:75,750,786...75,815,038
Ensembl chr 5:75,750,787...75,814,990
|
|
G |
Fkbp4 |
FKBP prolyl isomerase 4 |
decreases expression |
EXP |
trovafloxacin results in decreased expression of FKBP4 mRNA |
CTD |
PMID:24136188 |
|
NCBI chr 4:161,703,379...161,711,833
Ensembl chr 4:161,703,379...161,711,833
|
|
G |
Fkbp8 |
FKBP prolyl isomerase 8 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of FKBP8 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr16:18,895,608...18,902,648
Ensembl chr16:18,893,576...18,902,612
|
|
G |
Fkbpl |
FKBP prolyl isomerase like |
decreases expression |
ISO |
trovafloxacin results in decreased expression of FKBPL mRNA |
CTD |
PMID:35537566 |
|
NCBI chr20:4,099,845...4,101,315
Ensembl chr20:4,099,806...4,101,368
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|
G |
Flrt2 |
fibronectin leucine rich transmembrane protein 2 |
increases expression |
ISO |
trovafloxacin results in increased expression of FLRT2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 6:114,777,547...114,872,688
Ensembl chr 6:114,777,599...114,872,785
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|
G |
Fmo3 |
flavin containing dimethylaniline monoxygenase 3 |
increases expression |
EXP |
trovafloxacin results in increased expression of FMO3 mRNA |
CTD |
PMID:24136188 |
|
NCBI chr13:75,309,367...75,334,915
Ensembl chr13:75,309,374...75,328,028
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|
G |
Fmo5 |
flavin containing dimethylaniline monoxygenase 5 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of FMO5 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 2:185,197,184...185,249,699
Ensembl chr 2:185,222,204...185,249,693
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|
G |
Fnbp1l |
formin binding protein 1-like |
increases expression |
ISO |
trovafloxacin results in increased expression of FNBP1L mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 2:210,647,241...210,748,203
Ensembl chr 2:210,647,246...210,738,455
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|
G |
Fnbp4 |
formin binding protein 4 |
increases expression |
ISO |
trovafloxacin results in increased expression of FNBP4 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 3:76,733,012...76,763,077
Ensembl chr 3:76,733,027...76,763,079
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|
G |
Fndc8 |
fibronectin type III domain containing 8 |
increases expression |
ISO |
trovafloxacin results in increased expression of FNDC8 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:67,825,952...67,834,090
Ensembl chr10:67,825,952...67,834,090
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|
G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
multiple interactions increases expression |
ISO |
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of FOS mRNA trovafloxacin results in increased expression of FOS mRNA |
CTD |
PMID:18930950 PMID:35537566 |
|
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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|
G |
Fosl1 |
FOS like 1, AP-1 transcription factor subunit |
increases expression |
ISO |
trovafloxacin results in increased expression of FOSL1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
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|
G |
Fosl2 |
FOS like 2, AP-1 transcription factor subunit |
increases expression |
ISO |
trovafloxacin results in increased expression of FOSL2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 6:24,297,898...24,319,219
Ensembl chr 6:24,300,956...24,320,034
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|
G |
Foxm1 |
forkhead box M1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of FOXM1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 4:161,639,538...161,652,012
Ensembl chr 4:161,638,816...161,650,684
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|
G |
Frat2 |
FRAT regulator of WNT signaling pathway 2 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of FRAT2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:240,654,120...240,656,449
Ensembl chr 1:240,654,137...240,656,517
|
|
G |
Frs3 |
fibroblast growth factor receptor substrate 3 |
increases expression |
ISO |
trovafloxacin results in increased expression of FRS3 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 9:13,288,559...13,297,285
Ensembl chr 9:13,288,667...13,295,382
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|
G |
Fry |
FRY microtubule binding protein |
decreases expression |
ISO |
trovafloxacin results in decreased expression of FRY mRNA |
CTD |
PMID:35537566 |
|
NCBI chr12:4,493,890...4,887,118
Ensembl chr12:4,493,891...4,799,116
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|
G |
Fubp1 |
far upstream element binding protein 1 |
increases expression |
ISO |
trovafloxacin results in increased expression of FUBP1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 2:241,159,481...241,186,591
Ensembl chr 2:241,159,512...241,186,602
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|
G |
Fut10 |
fucosyltransferase 10 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of FUT10 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr16:60,868,761...60,958,762
Ensembl chr16:60,877,952...60,958,683
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|
G |
Fut4 |
fucosyltransferase 4 |
increases expression |
ISO |
trovafloxacin results in increased expression of FUT4 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 8:11,586,721...11,590,682
Ensembl chr 8:11,586,721...11,590,682
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|
G |
Fut8 |
fucosyltransferase 8 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of FUT8 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 6:95,949,246...96,176,677
Ensembl chr 6:95,949,991...96,176,677
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|
G |
Fuz |
fuzzy planar cell polarity protein |
decreases expression |
ISO |
trovafloxacin results in decreased expression of FUZ mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:95,379,542...95,384,532
Ensembl chr 1:95,379,587...95,384,530
|
|
G |
Fzd7 |
frizzled class receptor 7 |
multiple interactions |
ISO |
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of FZD7 mRNA |
CTD |
PMID:18930950 |
|
NCBI chr 9:60,931,433...60,934,252
Ensembl chr 9:60,930,875...60,935,781
|
|
G |
Fzd8 |
frizzled class receptor 8 |
increases expression |
ISO |
trovafloxacin results in increased expression of FZD8 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr17:57,312,924...57,320,551
Ensembl chr17:57,314,450...57,320,650
|
|
G |
G2e3 |
G2/M-phase specific E3 ubiquitin protein ligase |
decreases expression |
ISO |
trovafloxacin results in decreased expression of G2E3 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 6:68,763,847...68,795,305
Ensembl chr 6:68,764,185...68,793,924
|
|
G |
G6pc1 |
glucose-6-phosphatase catalytic subunit 1 |
multiple interactions |
ISO |
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of G6PC1 mRNA |
CTD |
PMID:18930950 |
|
NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804
|
|
G |
G6pd |
glucose-6-phosphate dehydrogenase |
decreases expression |
EXP |
trovafloxacin results in decreased expression of G6PD mRNA |
CTD |
PMID:24136188 |
|
NCBI chr X:152,201,081...152,220,863
Ensembl chr X:152,201,098...152,220,801
|
|
G |
Gaa |
alpha glucosidase |
decreases expression |
ISO |
trovafloxacin results in decreased expression of GAA mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:104,529,673...104,546,836
Ensembl chr10:104,529,747...104,546,836
|
|
G |
Gabarapl1 |
GABA type A receptor associated protein like 1 |
multiple interactions increases expression |
ISO |
[trovafloxacin co-treated with TNF protein] results in increased expression of GABARAPL1 mRNA trovafloxacin results in increased expression of GABARAPL1 mRNA |
CTD |
PMID:33609687 |
|
NCBI chr 4:162,980,309...162,989,452
Ensembl chr 4:162,980,249...162,989,450
|
|
G |
Gabarapl2 |
GABA type A receptor associated protein like 2 |
multiple interactions increases expression |
ISO |
TNF protein inhibits the reaction [trovafloxacin results in increased expression of GABARAPL2 mRNA] |
CTD |
PMID:33609687 |
|
NCBI chr19:39,910,572...39,921,408
Ensembl chr19:39,910,534...39,924,628 Ensembl chr 8:39,910,534...39,924,628
|
|
G |
Gadd45a |
growth arrest and DNA-damage-inducible, alpha |
decreases expression |
ISO |
trovafloxacin results in decreased expression of GADD45A mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
|
|
G |
Gadd45b |
growth arrest and DNA-damage-inducible, beta |
increases expression |
ISO |
trovafloxacin results in increased expression of GADD45B mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046
|
|
G |
Gadd45g |
growth arrest and DNA-damage-inducible, gamma |
decreases expression increases expression |
EXP ISO |
trovafloxacin results in decreased expression of GADD45G mRNA trovafloxacin results in increased expression of GADD45G mRNA |
CTD |
PMID:24136188 PMID:35537566 |
|
NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610
|
|
G |
Gal3st4 |
galactose-3-O-sulfotransferase 4 |
increases expression |
ISO |
trovafloxacin results in increased expression of GAL3ST4 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr12:17,267,963...17,276,951
Ensembl chr12:17,267,963...17,276,833
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|
G |
Galc |
galactosylceramidase |
decreases expression |
ISO |
trovafloxacin results in decreased expression of GALC mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 6:117,452,888...117,522,281
Ensembl chr 6:117,452,895...117,515,830
|
|
G |
Gan |
gigaxonin |
increases expression |
ISO |
trovafloxacin results in increased expression of GAN mRNA |
CTD |
PMID:35537566 |
|
NCBI chr19:45,207,783...45,265,066
Ensembl chr19:45,207,184...45,254,107
|
|
G |
Ganc |
glucosidase, alpha; neutral C |
decreases expression |
ISO |
trovafloxacin results in decreased expression of GANC mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 3:107,353,369...107,406,104
Ensembl chr 3:107,353,369...107,405,241
|
|
G |
Gapdh |
glyceraldehyde-3-phosphate dehydrogenase |
decreases expression |
EXP |
trovafloxacin results in decreased expression of GAPDH mRNA |
CTD |
PMID:24136188 |
|
NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
|
|
G |
Gapdhs |
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic |
increases expression |
ISO |
trovafloxacin results in increased expression of GAPDHS mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:85,979,096...85,994,153
Ensembl chr 1:85,979,098...85,993,640
|
|
G |
Gars1 |
glycyl-tRNA synthetase 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of GARS1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 4:84,171,596...84,212,609
Ensembl chr 4:84,171,596...84,212,609
|
|
G |
Gas2 |
growth arrest-specific 2 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of GAS2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:101,452,361...101,582,619
Ensembl chr 1:101,482,591...101,582,619
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|
G |
Gas5 |
growth arrest specific 5 |
increases expression |
ISO |
trovafloxacin results in increased expression of GAS5 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr13:73,303,611...73,306,932
|
|
G |
Gas8 |
growth arrest specific 8 |
increases expression |
ISO |
trovafloxacin results in increased expression of GAS8 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr19:51,552,770...51,572,323
Ensembl chr19:51,552,816...51,572,305
|
|
G |
Gbp1 |
guanylate binding protein 1 |
increases expression |
ISO |
trovafloxacin results in increased expression of GBP2B mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 2:231,398,136...231,432,773
Ensembl chr 2:231,398,163...231,432,131 Ensembl chr 2:231,398,163...231,432,131
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|
G |
Gbp2 |
guanylate binding protein 2 |
increases expression |
ISO |
trovafloxacin results in increased expression of GBP2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 2:231,332,488...231,348,573
Ensembl chr 2:231,332,284...231,348,571
|
|
G |
Gbp6 |
guanylate binding protein family member 6 |
increases expression |
ISO |
trovafloxacin results in increased expression of GBP6 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr14:4,730,286...4,756,508
Ensembl chr14:4,730,453...4,839,062 Ensembl chr14:4,730,453...4,839,062
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|
G |
Gbp7 |
guanylate binding protein 7 |
increases expression |
ISO |
trovafloxacin results in increased expression of GBP7 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 2:231,275,521...231,297,289
Ensembl chr 2:231,275,640...231,297,278
|
|
G |
Gcat |
glycine C-acetyltransferase |
decreases expression |
ISO |
trovafloxacin results in decreased expression of GCAT mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 7:110,595,126...110,601,474
Ensembl chr 7:110,595,091...110,601,473
|
|
G |
Gcgr |
glucagon receptor |
multiple interactions |
ISO |
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of GCGR mRNA |
CTD |
PMID:18930950 |
|
NCBI chr10:105,808,474...105,816,641
Ensembl chr10:105,808,473...105,816,640
|
|
G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
decreases expression multiple interactions |
EXP ISO |
trovafloxacin results in decreased expression of GCLC mRNA [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of GCLC mRNA |
CTD |
PMID:18930950 PMID:24136188 |
|
NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
|
|
G |
Gen1 |
GEN1 Holliday junction 5' flap endonuclease |
decreases expression |
ISO |
trovafloxacin results in decreased expression of GEN1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 6:33,947,599...33,978,461
Ensembl chr 6:33,948,206...33,978,401
|
|
G |
Get1 |
guided entry of tail-anchored proteins factor 1 |
increases expression |
ISO |
trovafloxacin results in increased expression of WRB mRNA |
CTD |
PMID:35537566 |
|
NCBI chr11:35,438,555...35,460,156
Ensembl chr11:35,445,815...35,459,973
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|
G |
Gfm1 |
G elongation factor, mitochondrial 1 |
decreases expression |
EXP |
trovafloxacin results in decreased expression of GFM1 mRNA |
CTD |
PMID:24136188 |
|
NCBI chr 2:151,700,573...151,745,477
Ensembl chr 2:151,700,564...151,745,471
|
|
G |
Gfod2 |
Gfo/Idh/MocA-like oxidoreductase domain containing 2 |
increases expression |
ISO |
trovafloxacin results in increased expression of GFOD2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr19:33,599,689...33,647,060
Ensembl chr19:33,604,187...33,647,004
|
|
G |
Ggcx |
gamma-glutamyl carboxylase |
decreases expression |
EXP |
trovafloxacin results in decreased expression of GGCX mRNA |
CTD |
PMID:24136188 |
|
NCBI chr 4:104,469,737...104,485,631
Ensembl chr 4:104,469,765...104,487,063
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|
G |
Gins2 |
GINS complex subunit 2 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of GINS2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr19:48,626,770...48,639,523
Ensembl chr19:48,626,770...48,639,339
|
|
G |
Gipc1 |
GIPC PDZ domain containing family, member 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of GIPC1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr19:24,474,291...24,487,083
Ensembl chr19:24,453,123...24,486,997
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|
G |
Gja1 |
gap junction protein, alpha 1 |
multiple interactions increases expression |
ISO |
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of GJA1 mRNA trovafloxacin results in increased expression of GJA1 mRNA |
CTD |
PMID:18930950 PMID:35537566 |
|
NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
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|
G |
Glis2 |
GLIS family zinc finger 2 |
increases expression |
ISO |
trovafloxacin results in increased expression of GLIS2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:10,951,157...10,978,524
Ensembl chr10:10,951,371...10,971,578
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|
G |
Glmp |
glycosylated lysosomal membrane protein |
decreases expression |
ISO |
trovafloxacin results in decreased expression of GLMP mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 2:173,794,273...173,797,863
Ensembl chr 2:173,794,255...173,799,960
|
|
G |
Glp2r |
glucagon-like peptide 2 receptor |
increases expression |
ISO |
trovafloxacin results in increased expression of GLP2R mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:52,402,748...52,466,012
Ensembl chr10:52,402,748...52,466,012
|
|
G |
Glrx3 |
glutaredoxin 3 |
decreases expression |
EXP |
trovafloxacin results in decreased expression of GLRX3 mRNA |
CTD |
PMID:24136188 |
|
NCBI chr 1:192,241,707...192,272,012
Ensembl chr 1:192,241,701...192,272,010
|
|
G |
Gls2 |
glutaminase 2 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of GLS2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 7:617,252...633,424
Ensembl chr 7:617,288...633,426
|
|
G |
Glyat |
glycine-N-acyltransferase |
increases expression |
EXP |
trovafloxacin results in increased expression of GLYAT mRNA |
CTD |
PMID:24136188 |
|
NCBI chr 1:209,704,213...209,724,949
Ensembl chr 1:209,704,268...209,724,942
|
|
G |
Gmfb |
glia maturation factor, beta |
increases expression |
ISO |
trovafloxacin results in increased expression of GMFB mRNA |
CTD |
PMID:35537566 |
|
NCBI chr15:20,069,923...20,081,005
Ensembl chr15:20,067,263...20,080,331
|
|
G |
Gnat2 |
G protein subunit alpha transducin 2 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of GNAT2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 2:195,726,371...195,735,866
Ensembl chr 2:195,726,762...195,735,866
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|
G |
Gnl3 |
G protein nucleolar 3 |
increases expression |
EXP |
trovafloxacin results in increased expression of GNL3 mRNA |
CTD |
PMID:24136188 |
|
NCBI chr16:6,207,402...6,213,491
Ensembl chr16:6,207,402...6,213,392
|
|
G |
Gnpat |
glyceronephosphate O-acyltransferase |
decreases expression |
ISO |
trovafloxacin results in decreased expression of GNPAT mRNA |
CTD |
PMID:35537566 |
|
NCBI chr19:52,822,326...52,848,872
Ensembl chr19:52,822,319...52,852,361
|
|
G |
Gnpnat1 |
glucosamine-phosphate N-acetyltransferase 1 |
multiple interactions |
ISO |
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of GNPNAT1 mRNA |
CTD |
PMID:18930950 |
|
NCBI chr15:18,596,180...18,608,854
Ensembl chr15:18,596,442...18,608,739
|
|
G |
Gnptg |
N-acetylglucosamine-1-phosphate transferase subunit gamma |
decreases expression |
ISO |
trovafloxacin results in decreased expression of GNPTG mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:14,252,186...14,257,128
Ensembl chr10:14,251,136...14,257,096
|
|
G |
Golga2 |
golgin A2 |
multiple interactions |
ISO |
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of GOLGA2 mRNA |
CTD |
PMID:18930950 |
|
NCBI chr 3:15,583,862...15,604,279
Ensembl chr 3:15,584,039...15,604,279
|
|
G |
Golga4 |
golgin A4 |
multiple interactions |
ISO |
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of GOLGA4 mRNA |
CTD |
PMID:18930950 |
|
NCBI chr 8:118,208,200...118,285,003
|
|
G |
Gpaa1 |
glycosylphosphatidylinositol anchor attachment 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of GPAA1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 7:108,051,896...108,055,479
Ensembl chr 7:108,051,861...108,055,484
|
|
G |
Gpam |
glycerol-3-phosphate acyltransferase, mitochondrial |
decreases expression |
EXP |
trovafloxacin results in decreased expression of GPAM mRNA |
CTD |
PMID:24136188 |
|
NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639
|
|
G |
Gpat3 |
glycerol-3-phosphate acyltransferase 3 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of AGPAT9 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr14:8,715,367...8,768,051
Ensembl chr14:8,714,373...8,766,490
|
|
G |
Gpatch3 |
G patch domain containing 3 |
increases expression |
ISO |
trovafloxacin results in increased expression of GPATCH3 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 5:145,800,107...145,809,519
Ensembl chr 5:145,800,111...145,809,250
|
|
G |
Gpc1 |
glypican 1 |
increases expression |
ISO |
trovafloxacin results in increased expression of GPC1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 9:93,396,234...93,424,047
Ensembl chr 9:93,396,234...93,424,047
|
|
G |
Gphn |
gephyrin |
decreases expression |
ISO |
trovafloxacin results in decreased expression of GPHN mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 6:96,954,365...97,483,617
Ensembl chr 6:96,892,148...97,483,612
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|
G |
Gpld1 |
glycosylphosphatidylinositol specific phospholipase D1 |
increases expression |
EXP |
trovafloxacin results in increased expression of GPLD1 mRNA |
CTD |
PMID:24136188 |
|
NCBI chr17:40,084,427...40,132,035
Ensembl chr17:40,084,617...40,126,939
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G |
Gpr155 |
G protein-coupled receptor 155 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of GPR155 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 3:58,216,422...58,270,350
Ensembl chr 3:58,216,423...58,270,275
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G |
Gpr160 |
G protein-coupled receptor 160 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of GPR160 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 2:112,483,364...112,563,072
Ensembl chr 2:112,484,935...112,563,148
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G |
Gpr17 |
G protein-coupled receptor 17 |
increases expression |
ISO |
trovafloxacin results in increased expression of GPR17 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr18:23,576,232...23,583,153
Ensembl chr18:23,577,242...23,582,966
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G |
Gpr176 |
G protein-coupled receptor 176 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of GPR176 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 3:105,236,794...105,337,664
Ensembl chr 3:105,236,795...105,337,226
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G |
Gpr19 |
G protein-coupled receptor 19 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of GPR19 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 4:167,710,944...167,739,232
Ensembl chr 4:167,710,666...167,741,036
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G |
Gpr34 |
G protein-coupled receptor 34 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of GPR34 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr X:9,104,829...9,113,796
Ensembl chr X:9,104,565...9,148,601
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|
G |
Gpr35 |
G protein-coupled receptor 35 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of GPR35 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 9:93,527,165...93,539,573
Ensembl chr 9:93,527,127...93,539,299
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|
G |
Gpr65 |
G-protein coupled receptor 65 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of GPR65 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 6:117,515,786...117,536,514
Ensembl chr 6:117,515,648...117,536,512
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|
G |
Gpsm2 |
G-protein signaling modulator 2 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of GPSM2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 2:196,327,149...196,375,322
Ensembl chr 2:196,327,149...196,375,154
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|
G |
Gpt2 |
glutamic--pyruvic transaminase 2 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of GPT2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr19:21,526,800...21,561,314
Ensembl chr19:21,517,621...21,560,610
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|
G |
Grhl1 |
grainyhead-like transcription factor 1 |
increases expression |
ISO |
trovafloxacin results in increased expression of GRHL1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 6:41,207,325...41,257,516
Ensembl chr 6:41,207,348...41,254,301
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|
G |
Grin3b |
glutamate ionotropic receptor NMDA type subunit 3B |
increases expression |
ISO |
trovafloxacin results in increased expression of GRIN3B mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 7:9,730,861...9,737,183
Ensembl chr 7:9,730,862...9,737,183
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G |
Grwd1 |
glutamate-rich WD repeat containing 1 |
increases expression |
ISO |
trovafloxacin results in increased expression of GRWD1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:96,301,260...96,306,962
Ensembl chr 1:96,301,261...96,307,201
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|
G |
Gsr |
glutathione-disulfide reductase |
decreases expression |
EXP |
trovafloxacin results in decreased expression of GSR mRNA |
CTD |
PMID:24136188 |
|
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
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|
G |
Gss |
glutathione synthetase |
decreases expression |
EXP |
trovafloxacin results in decreased expression of GSS mRNA |
CTD |
PMID:24136188 |
|
NCBI chr 3:144,047,849...144,078,197
Ensembl chr 3:144,047,850...144,078,198
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|
G |
Gsta3 |
glutathione S-transferase alpha 3 |
decreases expression |
EXP |
trovafloxacin results in decreased expression of GSTA3 mRNA |
CTD |
PMID:24136188 |
|
NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240
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|
G |
Gtf3a |
general transcription factor III A |
decreases expression |
ISO |
trovafloxacin results in decreased expression of GTF3A mRNA |
CTD |
PMID:35537566 |
|
NCBI chr12:8,136,746...8,144,690
Ensembl chr12:8,136,747...8,144,690
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|
G |
Gtpbp2 |
GTP binding protein 2 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of GTPBP2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 9:14,813,964...14,823,419
Ensembl chr 9:14,813,964...14,823,241
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|
G |
Gtpbp6 |
GTP binding protein 6 (putative) |
increases expression |
ISO |
trovafloxacin results in increased expression of GTPBP6 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr12:46,574,913...46,578,873
Ensembl chr12:46,574,435...46,578,873
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|
G |
Gtse1 |
G-2 and S-phase expressed 1 |
increases expression |
ISO |
trovafloxacin results in increased expression of GTSE1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 7:116,949,997...116,966,826
Ensembl chr 7:116,950,053...116,966,806
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|
G |
Gvin1 |
GTPase, very large interferon inducible 1 |
increases expression |
ISO |
trovafloxacin results in increased expression of GVIN2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:160,279,767...160,306,701
Ensembl chr 1:160,277,126...160,306,331
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|
G |
H1f0 |
H1.0 linker histone |
decreases expression |
ISO |
trovafloxacin results in decreased expression of H1F0 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 7:110,592,834...110,594,694
Ensembl chr 7:110,592,208...110,594,694
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|
G |
H1f10 |
H1.10 linker histone |
decreases expression |
ISO |
trovafloxacin results in decreased expression of H1F10 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 4:120,440,515...120,441,578
Ensembl chr 4:120,440,870...120,441,448
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|
G |
H1f2 |
H1.2 linker histone, cluster member |
decreases expression |
ISO |
trovafloxacin results in decreased expression of H1F2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr17:41,391,106...41,392,597
Ensembl chr17:41,388,477...41,392,635
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|
G |
H1f4 |
H1.4 linker histone, cluster member |
decreases expression |
ISO |
trovafloxacin results in decreased expression of H1F4 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr17:41,486,574...41,487,355
Ensembl chr17:41,486,560...41,487,403
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|
G |
H1f5 |
H1.5 linker histone, cluster member |
decreases expression |
ISO |
trovafloxacin results in decreased expression of H1F5 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr17:42,726,132...42,727,162
Ensembl chr17:42,726,127...42,769,160
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|
G |
H2ac10 |
H2A clustered histone 10 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of H2AC10 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr17:41,570,532...41,571,020
Ensembl chr17:41,570,273...41,571,049
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|
G |
H2ac4 |
H2A clustered histone 4 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of H2AC4 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr17:42,799,884...42,800,387
Ensembl chr17:42,799,652...42,800,381
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|
G |
H2ax |
H2A.X variant histone |
multiple interactions increases expression increases phosphorylation decreases expression |
ISO |
[TNF protein co-treated with trovafloxacin] results in increased expression of H2AX protein modified form; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[TNF protein co-treated with trovafloxacin] results in increased expression of H2AX protein modified form]; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [trovafloxacin results in increased expression of H2AX protein modified form]; TNF protein promotes the reaction [trovafloxacin results in increased expression of H2AX protein modified form] trovafloxacin results in increased phosphorylation of H2AX protein trovafloxacin results in decreased expression of H2AX mRNA |
CTD |
PMID:24817034 PMID:25748550 PMID:35537566 |
|
NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
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|
G |
H2bc18 |
H2B clustered histone 18 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of H2BC18 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 2:183,838,331...183,842,769
Ensembl chr 2:183,838,334...183,841,529
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|
G |
H2bc3 |
H2B clustered histone 3 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of H2BC3 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr17:41,380,056...41,380,686
|
|
G |
H2bc6 |
H2B clustered histone 6 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of H2BC6 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr17:41,520,775...41,521,238
|
|
G |
H2bc8 |
H2B clustered histone 8 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of H2BC8 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr17:42,708,658...42,709,408
|
|
G |
H2bc9 |
H2B clustered histone 9 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of H2BC9 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr17:42,470,593...42,478,590
|
|
G |
H3c1 |
H3 clustered histone 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of H3C10 mRNA; trovafloxacin results in decreased expression of H3C4 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr17:41,368,379...41,368,902
Ensembl chr17:41,368,386...41,368,856 Ensembl chr17:41,368,386...41,368,856 Ensembl chr17:41,368,386...41,368,856 Ensembl chr17:41,368,386...41,368,856
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|
G |
H4cl1 |
histone H4C like 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of H4C6 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr17:41,368,743...41,426,735
|
|
G |
H4f3 |
H1.3 linker histone, cluster member |
decreases expression |
ISO |
trovafloxacin results in decreased expression of H1F3 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr17:41,551,524...41,552,303
Ensembl chr17:41,529,667...41,552,334
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|
G |
Hacd3 |
3-hydroxyacyl-CoA dehydratase 3 |
decreases expression |
EXP |
trovafloxacin results in decreased expression of HACD3 mRNA |
CTD |
PMID:24136188 |
|
NCBI chr 8:65,501,240...65,538,507
Ensembl chr 8:65,501,240...65,538,507
|
|
G |
Hacd4 |
3-hydroxyacyl-CoA dehydratase 4 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of HACD4 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 5:102,887,597...102,915,376
Ensembl chr 5:102,887,588...102,915,338
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|
G |
Hacl1 |
2-hydroxyacyl-CoA lyase 1 |
increases expression decreases expression |
EXP ISO |
trovafloxacin results in increased expression of HACL1 mRNA trovafloxacin results in decreased expression of HACL1 mRNA |
CTD |
PMID:24136188 PMID:35537566 |
|
NCBI chr16:6,826,881...6,863,027
Ensembl chr16:6,824,906...6,863,027
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|
G |
Hao2 |
hydroxyacid oxidase 2 |
increases expression |
EXP |
trovafloxacin results in increased expression of HAO2 mRNA |
CTD |
PMID:24136188 |
|
NCBI chr 2:186,200,137...186,232,997
Ensembl chr 2:186,200,504...186,224,425
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|
G |
Haspin |
histone H3 associated protein kinase |
decreases expression |
ISO |
trovafloxacin results in decreased expression of GSG2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:57,747,731...57,750,518
Ensembl chr10:57,747,573...57,750,512
|
|
G |
Haus4 |
HAUS augmin-like complex, subunit 4 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of HAUS4 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr15:27,994,530...28,006,147
Ensembl chr15:27,994,532...28,005,938
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|
G |
Haus5 |
HAUS augmin-like complex, subunit 5 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of HAUS5 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:85,912,371...85,924,327
Ensembl chr 1:85,912,374...85,923,337
|
|
G |
Hbegf |
heparin-binding EGF-like growth factor |
increases expression |
ISO |
trovafloxacin results in increased expression of HBEGF mRNA |
CTD |
PMID:35537566 |
|
NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441
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|
G |
Hcn2 |
hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of HCN2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 7:9,969,801...9,988,839
Ensembl chr 7:9,970,368...9,988,841
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|
G |
Hdhd3 |
haloacid dehalogenase-like hydrolase domain containing 3 |
increases expression |
ISO |
trovafloxacin results in increased expression of HDHD3 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 5:75,951,308...75,954,775
Ensembl chr 5:75,946,013...75,955,266
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|
G |
Hdlbp |
high density lipoprotein binding protein |
decreases expression |
ISO |
trovafloxacin results in decreased expression of HDLBP mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 9:93,948,099...94,018,040
Ensembl chr 9:93,949,913...94,018,048
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|
G |
Hemk1 |
HemK methyltransferase family member 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of HEMK1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 8:107,999,658...108,010,732
Ensembl chr 8:107,999,644...108,010,256
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|
G |
Herc1 |
HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of HERC1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 8:66,857,169...67,070,318
Ensembl chr 8:66,856,935...67,070,312
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|
G |
Herpud1 |
homocysteine inducible ER protein with ubiquitin like domain 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of HERPUD1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424
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|
G |
Hilpda |
hypoxia inducible lipid droplet-associated |
increases expression |
ISO |
trovafloxacin results in increased expression of HILPDA mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 4:57,871,088...57,874,048
Ensembl chr 4:57,871,110...57,874,557
|
|
G |
Hip1r |
huntingtin interacting protein 1 related |
decreases expression |
ISO |
trovafloxacin results in decreased expression of HIP1R mRNA |
CTD |
PMID:35537566 |
|
NCBI chr12:32,590,164...32,618,841
Ensembl chr12:32,590,165...32,618,734
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|
G |
Hirip3 |
HIRA interacting protein 3 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of HIRIP3 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 1:181,472,537...181,475,082
Ensembl chr 1:181,472,056...181,475,079
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|
G |
Hist1h2af |
histone cluster 1 H2A family member F |
decreases expression |
ISO |
trovafloxacin results in decreased expression of H2AC8 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr17:41,379,404...41,379,796
Ensembl chr17:41,379,404...41,379,796
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|
G |
Hist1h2ail1 |
histone cluster 1 H2a family member I like 1 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of H3C6 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr17:41,568,181...41,569,093
Ensembl chr17:41,568,471...41,569,109
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|
G |
Hist1h2bc |
histone cluster 1, H2bc |
decreases expression |
ISO |
trovafloxacin results in decreased expression of H2BC4 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr17:42,692,335...42,696,601
Ensembl chr17:42,694,723...42,696,642
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|
G |
Hist1h4b |
histone cluster 1 H4 family member B |
decreases expression |
ISO |
trovafloxacin results in decreased expression of H4C9 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr17:42,480,467...42,484,912
Ensembl chr17:42,480,313...42,485,370
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|
G |
Hist1h4m |
histone cluster 1, H4m |
decreases expression |
ISO |
trovafloxacin results in decreased expression of H4C1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr17:42,698,016...42,698,420
Ensembl chr17:42,698,025...42,698,958
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|
G |
Hltf |
helicase-like transcription factor |
decreases expression |
ISO |
trovafloxacin results in decreased expression of HLTF mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 2:102,549,724...102,609,492
Ensembl chr 2:102,549,724...102,609,327
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|
G |
Hmga2 |
high mobility group AT-hook 2 |
increases expression |
ISO |
trovafloxacin results in increased expression of HMGA2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784
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G |
Hmgb2 |
high mobility group box 2 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of HMGB2 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140
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|
G |
Hmgb3 |
high mobility group box 3 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of HMGB3 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr X:149,296,303...149,301,290
Ensembl chr X:149,296,375...149,301,292
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G |
Hmgn3 |
high mobility group nucleosomal binding domain 3 |
decreases expression |
EXP |
trovafloxacin results in decreased expression of HMGN3 mRNA |
CTD |
PMID:24136188 |
|
NCBI chr 8:84,022,493...84,059,329
Ensembl chr 8:84,022,495...84,062,976
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|
G |
Hmgn5 |
high mobility group nucleosome binding domain 5 |
decreases expression |
ISO |
trovafloxacin results in decreased expression of HMGN5 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr X:74,085,871...74,094,488
Ensembl chr X:74,085,875...74,094,441
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|
G |
Hmmr |
hyaluronan-mediated motility receptor |
decreases expression |
ISO |
trovafloxacin results in decreased expression of HMMR mRNA |
CTD |
PMID:35537566 |
|
NCBI chr10:25,132,933...25,163,029
Ensembl chr10:25,132,977...25,163,060
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|
G |
Hmox1 |
heme oxygenase 1 |
multiple interactions |
ISO |
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of HMOX1 mRNA |
CTD |
PMID:18930950 |
|
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
|
|
G |
Hnrnpa1 |
heterogeneous nuclear ribonucleoprotein A1 |
increases expression |
ISO |
trovafloxacin results in increased expression of HNRNPA1 mRNA |
CTD |
PMID:35537566 |
|
NCBI chr 7:134,375,318...134,381,610
Ensembl chr 7:134,375,150...134,381,609
|
|
G |
Hnrnpdl |
heterogeneous nuclear ribonucleoprotein D-like |
increases expression |
ISO |
trovafloxacin results in increased expression of HNRNPDL mRNA |
CTD |
PMID:35537566 |
|
NCBI chr14:9,557,430...9,563,659
Ensembl chr14:9,557,425...9,562,506
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G |
Hnrnpf |
heterogeneous nuclear ribonucleoprotein F |
multiple inter | |