CHEBI ONTOLOGY - ANNOTATIONS |
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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
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Term: | thapsigargin |
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Accession: | CHEBI:9516
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browse the term
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Definition: | An organic heterotricyclic compound that is a hexa-oxygenated 6,7-guaianolide isolated fron the roots of Thapsia garganica L., Apiaceae. A potent skin irritant, it is used in traditional medicine as a counter-irritant. Thapsigargin inhibits Ca(2+)-transporting ATPase mediated uptake of calcium ions into sarcoplasmic reticulum and is used in experimentation examining the impacts of increasing cytosolic calcium concentrations. |
Synonyms: | related_synonym: | (3S,3aR,4S,6S,6aR,7S,8S,9bS)-6-(acetyloxy)-4-(butanoyloxy)-3,3a-dihydroxy-3,6,9-trimethyl-8-{[(2Z)-2-methylbut-2-enoyl]oxy}-2-oxo-2,3,3a,4,5,6,6a,7,8,9b-decahydroazuleno[4,5-b]furan-7-yl octanoate; Formula=C34H50O12; InChI=1S/C34H50O12/c1-9-12-13-14-15-17-24(37)43-28-26-25(20(5)27(28)44-30(38)19(4)11-3)29-34(41,33(8,40)31(39)45-29)22(42-23(36)16-10-2)18-32(26,7)46-21(6)35/h11,22,26-29,40-41H,9-10,12-18H2,1-8H3/b19-11-/t22-,26+,27-,28-,29-,32-,33+,34+/m0/s1; InChIKey=IXFPJGBNCFXKPI-FSIHEZPISA-N; SMILES=[H][C@@]1(OC(=O)C(\\C)=C/C)[C@@H](OC(=O)CCCCCCC)[C@@]2([H])C(=C1C)[C@]1([H])OC(=O)[C@@](C)(O)[C@@]1(O)[C@H](C[C@]2(C)OC(C)=O)OC(=O)CCC; Tg; octanoic acid {3S-[3alpha,3abeta,4alpha,6beta,6abeta,7beta,8alpha(Z),9balpha]}-6-(acetoxy)-2,3,3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-[(2-methyl-1-oxo-2-butenyl)oxy]-2-oxo-4-(1-oxobutoxy)-azuleno[4,5-b]furan-7-yl ester; thapsigargine |
| alt_id: | CHEBI:363811; CHEBI:45970 |
| xref: | CAS:67526-95-8; KEGG:C09561; KNApSAcK:C00003375; LIPID_MAPS_instance:LMPR0103410001 |
| xref_mesh: | MESH:D019284 |
| xref: | PDBeChem:TG1; PMID:10477042; PMID:12410314; PMID:16874404; PMID:17825049; PMID:20357004; PMID:24598360; PMID:9014219; Reaxys:4649293; Wikipedia:Thapsigargin |
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AACS |
acetoacetyl-CoA synthetase |
increases expression |
ISO |
Thapsigargin results in increased expression of AACS protein |
CTD |
PMID:35544339 |
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NCBI chr12:125,065,435...125,143,316
Ensembl chr12:125,065,434...125,143,333
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AARS1 |
alanyl-tRNA synthetase 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of AARS1 protein |
CTD |
PMID:24648495 PMID:35544339 |
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NCBI chr16:70,252,298...70,289,506
Ensembl chr16:70,251,983...70,289,707
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ABCB1 |
ATP binding cassette subfamily B member 1 |
multiple interactions decreases expression |
EXP |
1-(4-chlorophenyl)-3-(3-(4-chlorophenyl)-5,5-dimethyl-1-(3-(5-nitrofuran-2-yl)allyldienehydrazinocarbonylmethyl)-2-oxoimidazolidin-4-yl)-1-hydroxyurea inhibits the reaction [Thapsigargin results in decreased expression of ABCB1 protein] Thapsigargin results in decreased expression of ABCB1 mRNA; Thapsigargin results in decreased expression of ABCB1 protein |
CTD |
PMID:34915026 |
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NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
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ABCC8 |
ATP binding cassette subfamily C member 8 |
increases expression |
ISO |
Thapsigargin results in increased expression of ABCC8 protein |
CTD |
PMID:35544339 |
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NCBI chr11:17,392,498...17,476,845
Ensembl chr11:17,392,498...17,476,894
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ABCF3 |
ATP binding cassette subfamily F member 3 |
increases expression |
ISO |
Thapsigargin results in increased expression of ABCF3 protein |
CTD |
PMID:35544339 |
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NCBI chr 3:184,186,199...184,194,005
Ensembl chr 3:184,186,095...184,194,012
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ABHD16A |
abhydrolase domain containing 16A, phospholipase |
increases expression |
ISO |
Thapsigargin results in increased expression of ABHD16A protein |
CTD |
PMID:35544339 |
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NCBI chr 6:31,686,955...31,703,324
Ensembl chr 6:31,686,955...31,703,356
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ABR |
ABR activator of RhoGEF and GTPase |
increases expression |
ISO |
Thapsigargin results in increased expression of ABR protein |
CTD |
PMID:35544339 |
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NCBI chr17:1,003,519...1,229,722
Ensembl chr17:1,003,519...1,229,738
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ACACA |
acetyl-CoA carboxylase alpha |
increases expression |
ISO |
Thapsigargin results in increased expression of ACACA protein |
CTD |
PMID:35544339 |
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NCBI chr17:37,084,992...37,406,836
Ensembl chr17:37,084,992...37,406,836
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ACAD11 |
acyl-CoA dehydrogenase family member 11 |
increases expression |
EXP |
Thapsigargin results in increased expression of ACAD11 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 3:132,558,141...132,659,809
Ensembl chr 3:132,558,138...132,660,082
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ACAD9 |
acyl-CoA dehydrogenase family member 9 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of ACAD9 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 3:128,879,620...128,913,114
Ensembl chr 3:128,879,596...128,924,003
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ACADVL |
acyl-CoA dehydrogenase very long chain |
increases expression |
EXP |
Thapsigargin results in increased expression of ACADVL mRNA |
CTD |
PMID:22378314 |
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NCBI chr17:7,217,125...7,225,266
Ensembl chr17:7,217,125...7,225,266
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ACAT2 |
acetyl-CoA acetyltransferase 2 |
decreases expression increases expression |
EXP ISO |
Thapsigargin results in decreased expression of ACAT2 mRNA Thapsigargin results in increased expression of ACAT2 protein |
CTD |
PMID:22378314 PMID:35544339 |
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NCBI chr 6:159,762,045...159,779,112
Ensembl chr 6:159,762,045...159,779,112
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ACBD3 |
acyl-CoA binding domain containing 3 |
increases expression |
EXP |
Thapsigargin results in increased expression of ACBD3 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 1:226,144,679...226,186,741
Ensembl chr 1:226,144,679...226,186,741
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ACKR1 |
atypical chemokine receptor 1 (Duffy blood group) |
increases expression |
EXP |
Thapsigargin results in increased expression of ACKR1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 1:159,204,875...159,206,500
Ensembl chr 1:159,204,875...159,206,500
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ACLY |
ATP citrate lyase |
increases expression |
ISO |
Thapsigargin results in increased expression of ACLY protein |
CTD |
PMID:24648495 PMID:35544339 |
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NCBI chr17:41,866,917...41,930,545
Ensembl chr17:41,866,917...41,930,542
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ACO1 |
aconitase 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of ACO1 protein |
CTD |
PMID:35544339 |
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NCBI chr 9:32,384,643...32,454,769
Ensembl chr 9:32,384,603...32,454,769
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ACO2 |
aconitase 2 |
increases expression |
ISO |
Thapsigargin results in increased expression of ACO2 protein |
CTD |
PMID:24648495 |
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NCBI chr22:41,469,117...41,528,974
Ensembl chr22:41,447,830...41,529,273
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ACOT13 |
acyl-CoA thioesterase 13 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of ACOT13 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 6:24,667,077...24,705,046
Ensembl chr 6:24,667,035...24,705,065
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ACOT2 |
acyl-CoA thioesterase 2 |
increases expression |
ISO |
Thapsigargin results in increased expression of ACOT2 protein |
CTD |
PMID:35544339 |
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NCBI chr14:73,567,620...73,575,658
Ensembl chr14:73,567,620...73,575,658
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ACOT7 |
acyl-CoA thioesterase 7 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of ACOT7 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 1:6,264,272...6,393,767
Ensembl chr 1:6,264,269...6,393,767
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ACSL5 |
acyl-CoA synthetase long chain family member 5 |
increases expression |
ISO |
Thapsigargin results in increased expression of ACSL5 protein |
CTD |
PMID:35544339 |
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NCBI chr10:112,374,116...112,428,376
Ensembl chr10:112,374,116...112,428,379
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ACTA2 |
actin alpha 2, smooth muscle |
increases expression decreases expression |
EXP |
Thapsigargin results in increased expression of ACTA2 mRNA Thapsigargin results in decreased expression of ACTA2 mRNA |
CTD |
PMID:22378314 PMID:29453283 |
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NCBI chr10:88,935,074...88,991,337
Ensembl chr10:88,934,822...88,991,339
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ACTG1 |
actin gamma 1 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of ACTG1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr17:81,509,971...81,512,799
Ensembl chr17:81,509,413...81,523,847
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ACTN1 |
actinin alpha 1 |
decreases expression |
EXP ISO |
Thapsigargin results in decreased expression of ACTN1 mRNA Thapsigargin results in decreased expression of ACTN1 protein |
CTD |
PMID:22378314 PMID:35544339 |
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NCBI chr14:68,874,128...68,979,302
Ensembl chr14:68,874,123...68,979,440
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ACTN4 |
actinin alpha 4 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ACTN4 protein |
CTD |
PMID:35544339 |
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NCBI chr19:38,647,649...38,731,589
Ensembl chr19:38,647,649...38,731,589
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ACTR1A |
actin related protein 1A |
increases expression |
ISO |
Thapsigargin results in increased expression of ACTR1A protein |
CTD |
PMID:35544339 |
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NCBI chr10:102,479,229...102,502,712
Ensembl chr10:102,461,881...102,502,712
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ACVR1 |
activin A receptor type 1 |
increases expression |
EXP |
Thapsigargin results in increased expression of ACVR1 mRNA |
CTD |
PMID:29453283 |
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NCBI chr 2:157,736,446...157,876,330
Ensembl chr 2:157,736,251...157,876,330
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ADAMTS4 |
ADAM metallopeptidase with thrombospondin type 1 motif 4 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of ADAMTS4 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 1:161,184,302...161,199,054
Ensembl chr 1:161,184,302...161,199,054
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ADAMTS9 |
ADAM metallopeptidase with thrombospondin type 1 motif 9 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of ADAMTS9 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 3:64,515,654...64,688,000
Ensembl chr 3:64,515,654...64,688,000
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ADD3 |
adducin 3 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ADD3 protein |
CTD |
PMID:35544339 |
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NCBI chr10:109,996,373...110,135,565
Ensembl chr10:109,996,368...110,135,565
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ADHFE1 |
alcohol dehydrogenase iron containing 1 |
increases expression |
EXP |
Thapsigargin results in increased expression of ADHFE1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 8:66,432,504...66,468,907
Ensembl chr 8:66,432,492...66,468,907
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ADI1 |
acireductone dioxygenase 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ADI1 protein |
CTD |
PMID:24648495 |
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NCBI chr 2:3,497,366...3,519,531
Ensembl chr 2:3,497,366...3,519,531
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ADM |
adrenomedullin |
decreases expression increases expression |
EXP |
Thapsigargin results in decreased expression of ADM mRNA Thapsigargin results in increased expression of ADM mRNA |
CTD |
PMID:20682585 PMID:22378314 |
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NCBI chr11:10,305,073...10,307,397
Ensembl chr11:10,305,073...10,307,397
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ADM2 |
adrenomedullin 2 |
increases expression |
EXP |
Thapsigargin results in increased expression of ADM2 mRNA |
CTD |
PMID:22378314 |
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NCBI chr22:50,481,543...50,486,437
Ensembl chr22:50,481,543...50,486,440
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ADRA2A |
adrenoceptor alpha 2A |
multiple interactions |
EXP |
Thapsigargin inhibits the reaction [Norepinephrine binds to and results in increased activity of ADRA2A protein] |
CTD |
PMID:10742289 |
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NCBI chr10:111,077,029...111,080,907
Ensembl chr10:111,077,029...111,080,907
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AFAP1 |
actin filament associated protein 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of AFAP1 protein |
CTD |
PMID:24648495 |
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NCBI chr 4:7,758,713...7,939,861
Ensembl chr 4:7,758,714...7,939,926
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AFDN |
afadin, adherens junction formation factor |
increases expression |
ISO |
Thapsigargin results in increased expression of AFDN protein |
CTD |
PMID:24648495 |
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NCBI chr 6:167,826,564...167,972,023
Ensembl chr 6:167,826,893...167,972,023
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AFG3L1P |
AFG3 like matrix AAA peptidase subunit 1, pseudogene |
decreases expression |
EXP |
Thapsigargin results in decreased expression of AFG3L1P mRNA |
CTD |
PMID:22378314 |
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NCBI chr16:89,972,580...90,000,787
Ensembl chr16:89,972,581...90,002,161 Ensembl chr16:89,972,581...90,002,161
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AGO3 |
argonaute RISC catalytic component 3 |
affects localization multiple interactions |
ISO |
Thapsigargin affects the localization of AGO3 mRNA Cycloheximide inhibits the reaction [Thapsigargin affects the localization of AGO3 mRNA]; Emetine inhibits the reaction [Thapsigargin affects the localization of AGO3 mRNA] |
CTD |
PMID:29576526 |
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NCBI chr 1:35,930,718...36,072,500
Ensembl chr 1:35,930,718...36,072,500
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AHNAK |
AHNAK nucleoprotein |
increases expression |
EXP |
Thapsigargin results in increased expression of AHNAK mRNA |
CTD |
PMID:19442820 |
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NCBI chr11:62,433,544...62,546,806
Ensembl chr11:62,433,542...62,556,235
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AHR |
aryl hydrocarbon receptor |
multiple interactions |
ISO |
Thapsigargin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein] |
CTD |
PMID:15364539 |
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NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152
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AIP |
aryl hydrocarbon receptor interacting protein |
decreases expression |
ISO |
Thapsigargin results in decreased expression of AIP protein |
CTD |
PMID:35544339 |
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NCBI chr11:67,483,026...67,491,103
Ensembl chr11:67,468,174...67,491,154
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AK2 |
adenylate kinase 2 |
decreases expression |
EXP ISO |
Thapsigargin results in decreased expression of AK2 mRNA Thapsigargin results in decreased expression of AK2 protein |
CTD |
PMID:22378314 PMID:35544339 |
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NCBI chr 1:33,007,940...33,036,883
Ensembl chr 1:33,007,986...33,080,996
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AK3 |
adenylate kinase 3 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of AK3 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 9:4,709,556...4,742,043
Ensembl chr 9:4,709,556...4,742,043
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AK4 |
adenylate kinase 4 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of AK4 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 1:65,147,552...65,232,145
Ensembl chr 1:65,147,549...65,232,145
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AKAP17A |
A-kinase anchoring protein 17A |
increases expression |
EXP |
Thapsigargin results in increased expression of AKAP17A mRNA |
CTD |
PMID:22378314 |
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NCBI chr X:1,591,604...1,602,520 NCBI chr Y:1,591,604...1,602,520
Ensembl chr Y:1,591,604...1,602,520 Ensembl chr X:1,591,604...1,602,520
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AKAP8L |
A-kinase anchoring protein 8 like |
increases expression |
ISO |
Thapsigargin results in increased expression of AKAP8L protein |
CTD |
PMID:24648495 |
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NCBI chr19:15,380,050...15,418,988
Ensembl chr19:15,380,050...15,419,141
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AKIRIN1 |
akirin 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of AKIRIN1 protein |
CTD |
PMID:24648495 |
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NCBI chr 1:38,991,276...39,006,059
Ensembl chr 1:38,991,276...39,006,059
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AKNA |
AT-hook transcription factor |
increases expression |
EXP |
Thapsigargin results in increased expression of AKNA mRNA |
CTD |
PMID:22378314 |
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NCBI chr 9:114,330,504...114,398,472
Ensembl chr 9:114,334,156...114,394,405
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AKT1 |
AKT serine/threonine kinase 1 |
multiple interactions increases phosphorylation decreases phosphorylation decreases expression |
EXP ISO |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Thapsigargin results in increased phosphorylation of AKT1 protein]; NRF1 protein inhibits the reaction [Thapsigargin results in decreased phosphorylation of AKT1 protein]; TFAM protein inhibits the reaction [Thapsigargin results in decreased phosphorylation of AKT1 protein] 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Thapsigargin results in increased phosphorylation of AKT1 protein]; Wortmannin inhibits the reaction [Thapsigargin results in increased phosphorylation of AKT1 protein] [Thapsigargin co-treated with HRAS protein] results in increased phosphorylation of AKT1 protein Thapsigargin results in decreased expression of AKT1 protein modified form |
CTD |
PMID:15339911 PMID:16338971 PMID:22378314 PMID:24898257 PMID:25398788 |
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NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759
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AKTIP |
AKT interacting protein |
decreases expression |
ISO |
Thapsigargin results in decreased expression of AKTIP protein |
CTD |
PMID:24648495 |
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NCBI chr16:53,491,040...53,504,412
Ensembl chr16:53,491,040...53,504,411
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ALCAM |
activated leukocyte cell adhesion molecule |
increases expression |
EXP |
Thapsigargin results in increased expression of ALCAM mRNA |
CTD |
PMID:22378314 |
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NCBI chr 3:105,366,909...105,576,900
Ensembl chr 3:105,366,909...105,576,900
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ALDH18A1 |
aldehyde dehydrogenase 18 family member A1 |
increases expression |
ISO |
Thapsigargin results in increased expression of ALDH18A1 protein |
CTD |
PMID:24648495 |
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NCBI chr10:95,605,941...95,656,711
Ensembl chr10:95,605,941...95,656,711
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ALDH1A1 |
aldehyde dehydrogenase 1 family member A1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ALDH1A1 protein |
CTD |
PMID:35544339 |
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NCBI chr 9:72,900,671...72,953,053
Ensembl chr 9:72,900,671...73,080,442
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ALDH1A2 |
aldehyde dehydrogenase 1 family member A2 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of ALDH1A2 mRNA |
CTD |
PMID:29453283 |
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NCBI chr15:57,953,429...58,065,711
Ensembl chr15:57,953,424...58,497,866
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ALDH1A3 |
aldehyde dehydrogenase 1 family member A3 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of ALDH1A3 mRNA |
CTD |
PMID:22378314 |
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NCBI chr15:100,879,831...100,916,626
Ensembl chr15:100,861,924...100,916,626
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ALDH3A2 |
aldehyde dehydrogenase 3 family member A2 |
increases expression |
ISO |
Thapsigargin results in increased expression of ALDH3A2 protein |
CTD |
PMID:35544339 |
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NCBI chr17:19,648,136...19,677,596
Ensembl chr17:19,648,136...19,685,760
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ALDH5A1 |
aldehyde dehydrogenase 5 family member A1 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of ALDH5A1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 6:24,494,969...24,537,207
Ensembl chr 6:24,494,867...24,537,207
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ALDH6A1 |
aldehyde dehydrogenase 6 family member A1 |
increases expression |
EXP |
Thapsigargin results in increased expression of ALDH6A1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr14:74,056,847...74,084,453
Ensembl chr14:74,056,847...74,084,492
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ALDH7A1 |
aldehyde dehydrogenase 7 family member A1 |
increases expression |
ISO |
Thapsigargin results in increased expression of ALDH7A1 protein |
CTD |
PMID:35544339 |
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NCBI chr 5:126,541,841...126,595,219
Ensembl chr 5:126,531,200...126,595,362
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ALDOA |
aldolase, fructose-bisphosphate A |
increases expression |
ISO |
Thapsigargin results in increased expression of ALDOA protein |
CTD |
PMID:35544339 |
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NCBI chr16:30,064,279...30,070,420
Ensembl chr16:30,064,164...30,070,457
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ALDOC |
aldolase, fructose-bisphosphate C |
decreases expression |
EXP |
Thapsigargin results in decreased expression of ALDOC mRNA |
CTD |
PMID:22378314 |
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NCBI chr17:28,573,120...28,576,895
Ensembl chr17:28,573,115...28,576,948
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ALG5 |
ALG5 dolichyl-phosphate beta-glucosyltransferase |
increases expression |
EXP |
Thapsigargin results in increased expression of ALG5 mRNA |
CTD |
PMID:22378314 PMID:29453283 |
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NCBI chr13:36,949,738...36,999,367
Ensembl chr13:36,949,738...37,000,763
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ALOX5 |
arachidonate 5-lipoxygenase |
multiple interactions |
EXP |
1-Butanol inhibits the reaction [Thapsigargin results in increased activity of and results in increased localization of ALOX5 protein]; 1-oleoyl-2-acetoyl-sn-glycerol inhibits the reaction [1-Butanol inhibits the reaction [Thapsigargin results in increased activity of and results in increased localization of ALOX5 protein]]; SB 203580 inhibits the reaction [Thapsigargin results in increased phosphorylation of and results in increased activity of ALOX5 protein]; Thapsigargin results in increased activity of and results in increased localization of ALOX5 protein; Thapsigargin results in increased phosphorylation of and results in increased activity of ALOX5 protein |
CTD |
PMID:10779545 PMID:18218859 |
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NCBI chr10:45,374,216...45,446,117
Ensembl chr10:45,374,176...45,446,119
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ALPP |
alkaline phosphatase, placental |
increases expression |
EXP |
Thapsigargin results in increased expression of ALPP mRNA |
CTD |
PMID:29453283 |
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NCBI chr 2:232,378,751...232,382,889
Ensembl chr 2:232,378,724...232,382,889
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AMOT |
angiomotin |
decreases expression |
EXP |
Thapsigargin results in decreased expression of AMOT mRNA |
CTD |
PMID:29453283 |
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NCBI chr X:112,774,877...112,840,831
Ensembl chr X:112,774,503...112,840,831
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AMT |
aminomethyltransferase |
increases expression |
EXP |
Thapsigargin results in increased expression of AMT mRNA |
CTD |
PMID:22378314 |
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NCBI chr 3:49,416,778...49,422,473
Ensembl chr 3:49,416,778...49,422,685
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AMY1B |
amylase alpha 1B |
decreases expression |
EXP |
Thapsigargin results in decreased expression of AMY1B mRNA |
CTD |
PMID:22378314 |
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NCBI chr 1:103,687,415...103,696,453
Ensembl chr 1:103,687,415...103,696,454
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AMY1C |
amylase alpha 1C |
decreases expression |
EXP |
Thapsigargin results in decreased expression of AMY1C mRNA |
CTD |
PMID:22378314 |
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NCBI chr 1:103,749,654...103,758,692
Ensembl chr 1:103,745,323...103,758,726
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ANGPTL2 |
angiopoietin like 2 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ANGPTL2 protein |
CTD |
PMID:24648495 |
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NCBI chr 9:127,087,348...127,122,635
Ensembl chr 9:127,087,348...127,122,635
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ANGPTL3 |
angiopoietin like 3 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of ANGPTL3 mRNA |
CTD |
PMID:32535746 |
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NCBI chr 1:62,597,520...62,606,313
Ensembl chr 1:62,597,520...62,606,313
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G |
ANK3 |
ankyrin 3 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ANK3 protein |
CTD |
PMID:35544339 |
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NCBI chr10:60,026,298...60,733,528
Ensembl chr10:60,026,298...60,733,490
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ANKH |
ANKH inorganic pyrophosphate transport regulator |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ANKH protein |
CTD |
PMID:35544339 |
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NCBI chr 5:14,704,800...14,871,778
Ensembl chr 5:14,704,800...14,871,778
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ANKRD10 |
ankyrin repeat domain 10 |
increases expression |
EXP |
Thapsigargin results in increased expression of ANKRD10 mRNA |
CTD |
PMID:29453283 |
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NCBI chr13:110,878,540...110,915,069
Ensembl chr13:110,878,540...110,915,069
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ANKRD17 |
ankyrin repeat domain 17 |
increases expression |
ISO |
Thapsigargin results in increased expression of ANKRD17 protein |
CTD |
PMID:24648495 |
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NCBI chr 4:73,073,376...73,258,798
Ensembl chr 4:73,073,376...73,258,798
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ANTXR2 |
ANTXR cell adhesion molecule 2 |
increases expression |
EXP |
Thapsigargin results in increased expression of ANTXR2 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 4:79,901,146...80,073,472
Ensembl chr 4:79,901,146...80,125,454
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ANXA1 |
annexin A1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ANXA1 protein |
CTD |
PMID:35544339 |
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NCBI chr 9:73,151,865...73,170,393
Ensembl chr 9:73,151,865...73,170,629
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ANXA4 |
annexin A4 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ANXA4 protein |
CTD |
PMID:35544339 |
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NCBI chr 2:69,643,808...69,827,112
Ensembl chr 2:69,644,425...69,827,112
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ANXA5 |
annexin A5 |
increases expression |
EXP ISO |
Thapsigargin results in increased expression of ANXA5 mRNA Thapsigargin results in increased expression of ANXA5 protein |
CTD |
PMID:22378314 PMID:35544339 |
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NCBI chr 4:121,667,946...121,696,980
Ensembl chr 4:121,667,946...121,696,995
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AP2M1 |
adaptor related protein complex 2 subunit mu 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of AP2M1 protein |
CTD |
PMID:24648495 |
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NCBI chr 3:184,174,855...184,184,091
Ensembl chr 3:184,174,689...184,184,214
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G |
AP3B1 |
adaptor related protein complex 3 subunit beta 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of AP3B1 protein |
CTD |
PMID:24648495 |
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NCBI chr 5:78,000,522...78,294,698
Ensembl chr 5:77,991,640...78,294,762
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APEH |
acylaminoacyl-peptide hydrolase |
increases expression |
ISO |
Thapsigargin results in increased expression of APEH protein |
CTD |
PMID:35544339 |
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NCBI chr 3:49,673,117...49,683,971
Ensembl chr 3:49,674,014...49,683,971
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G |
APOB |
apolipoprotein B |
decreases secretion decreases expression |
EXP |
Thapsigargin results in decreased secretion of APOB protein Thapsigargin results in decreased expression of APOB mRNA |
CTD |
PMID:32535746 |
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NCBI chr 2:21,001,429...21,044,073
Ensembl chr 2:21,001,429...21,044,073
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G |
APOC3 |
apolipoprotein C3 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of APOC3 mRNA |
CTD |
PMID:32535746 |
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NCBI chr11:116,829,907...116,833,072
Ensembl chr11:116,829,706...116,833,072
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G |
APP |
amyloid beta precursor protein |
increases expression |
ISO |
Thapsigargin results in increased expression of APP protein |
CTD |
PMID:35544339 |
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NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128
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G |
AQR |
aquarius intron-binding spliceosomal factor |
increases expression |
ISO |
Thapsigargin results in increased expression of AQR protein |
CTD |
PMID:24648495 |
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NCBI chr15:34,851,782...34,969,742
Ensembl chr15:34,851,782...34,969,742
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AR |
androgen receptor |
multiple interactions |
EXP |
Thapsigargin results in increased degradation of and results in decreased expression of AR protein |
CTD |
PMID:30280407 |
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NCBI chr X:67,544,021...67,730,619
Ensembl chr X:67,544,021...67,730,619
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G |
ARAF |
A-Raf proto-oncogene, serine/threonine kinase |
increases expression |
ISO |
Thapsigargin results in increased expression of ARAF protein |
CTD |
PMID:35544339 |
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NCBI chr X:47,561,205...47,571,908
Ensembl chr X:47,561,205...47,571,908
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G |
ARCN1 |
archain 1 |
increases expression |
EXP ISO |
Thapsigargin results in increased expression of ARCN1 mRNA Thapsigargin results in increased expression of ARCN1 protein |
CTD |
PMID:22378314 PMID:35544339 |
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NCBI chr11:118,572,409...118,603,033
Ensembl chr11:118,572,390...118,603,033
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G |
ARF3 |
ARF GTPase 3 |
decreases expression increases expression |
EXP ISO |
Thapsigargin results in decreased expression of ARF3 mRNA Thapsigargin results in increased expression of ARF3 protein |
CTD |
PMID:29453283 PMID:35544339 |
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NCBI chr12:48,935,723...48,957,487
Ensembl chr12:48,935,723...48,957,487
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ARF4 |
ARF GTPase 4 |
increases expression |
EXP ISO |
Thapsigargin results in increased expression of ARF4 mRNA Thapsigargin results in increased expression of ARF4 protein |
CTD |
PMID:22378314 PMID:35544339 |
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NCBI chr 3:57,571,363...57,597,344
Ensembl chr 3:57,571,363...57,598,220
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ARFGAP3 |
ARF GTPase activating protein 3 |
increases expression |
EXP ISO |
Thapsigargin results in increased expression of ARFGAP3 mRNA Thapsigargin results in increased expression of ARFGAP3 protein |
CTD |
PMID:22378314 PMID:35544339 |
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NCBI chr22:42,796,502...42,857,273
Ensembl chr22:42,796,502...42,858,106
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ARFIP1 |
ARF interacting protein 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of ARFIP1 protein |
CTD |
PMID:35544339 |
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NCBI chr 4:152,779,954...152,912,357
Ensembl chr 4:152,779,937...152,918,463
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ARG2 |
arginase 2 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of ARG2 mRNA |
CTD |
PMID:22378314 |
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NCBI chr14:67,619,920...67,651,708
Ensembl chr14:67,619,920...67,651,708
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ARHGAP17 |
Rho GTPase activating protein 17 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ARHGAP17 protein |
CTD |
PMID:35544339 |
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NCBI chr16:24,919,389...25,015,369
Ensembl chr16:24,919,389...25,015,666
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ARHGDIA |
Rho GDP dissociation inhibitor alpha |
increases expression |
ISO |
Thapsigargin results in increased expression of ARHGDIA protein |
CTD |
PMID:35544339 |
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NCBI chr17:81,867,721...81,871,337
Ensembl chr17:81,867,719...81,871,378
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ARHGEF2 |
Rho/Rac guanine nucleotide exchange factor 2 |
increases expression |
EXP |
Thapsigargin results in increased expression of ARHGEF2 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 1:155,946,854...155,979,617
Ensembl chr 1:155,946,851...156,007,070
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ARID4A |
AT-rich interaction domain 4A |
increases expression |
ISO |
Thapsigargin results in increased expression of ARID4A protein |
CTD |
PMID:24648495 |
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NCBI chr14:58,298,555...58,373,876
Ensembl chr14:58,298,504...58,373,887
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ARID4B |
AT-rich interaction domain 4B |
increases expression |
ISO |
Thapsigargin results in increased expression of ARID4B protein |
CTD |
PMID:24648495 |
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NCBI chr 1:235,166,902...235,328,179
Ensembl chr 1:235,131,634...235,328,219
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ARL1 |
ARF like GTPase 1 |
increases expression |
EXP |
Thapsigargin results in increased expression of ARL1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr12:101,393,116...101,407,820
Ensembl chr12:101,393,116...101,407,772
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G |
ARMCX1 |
armadillo repeat containing X-linked 1 |
increases expression |
EXP |
Thapsigargin results in increased expression of ARMCX1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr X:101,550,547...101,554,700
Ensembl chr X:101,550,547...101,554,700
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G |
ARMCX3 |
armadillo repeat containing X-linked 3 |
increases expression |
EXP ISO |
Thapsigargin results in increased expression of ARMCX3 mRNA Thapsigargin results in increased expression of ARMCX3 protein |
CTD |
PMID:22378314 PMID:35544339 |
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NCBI chr X:101,623,151...101,627,843
Ensembl chr X:101,622,797...101,627,843
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G |
ARPC3 |
actin related protein 2/3 complex subunit 3 |
increases expression |
EXP |
Thapsigargin results in increased expression of ARPC3 mRNA |
CTD |
PMID:22378314 |
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NCBI chr12:110,434,823...110,450,337
Ensembl chr12:110,434,823...110,450,422
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G |
ARSB |
arylsulfatase B |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ARSB protein |
CTD |
PMID:35544339 |
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NCBI chr 5:78,777,209...78,985,958
Ensembl chr 5:78,777,209...78,986,087
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G |
ASB5 |
ankyrin repeat and SOCS box containing 5 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ASB5 protein |
CTD |
PMID:24648495 |
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NCBI chr 4:176,213,673...176,277,524
Ensembl chr 4:176,213,673...176,277,571
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G |
ASCL1 |
achaete-scute family bHLH transcription factor 1 |
increases expression |
EXP |
Thapsigargin results in increased expression of ASCL1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr12:102,957,674...102,960,513
Ensembl chr12:102,957,674...102,960,513
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G |
ASF1B |
anti-silencing function 1B histone chaperone |
decreases expression |
EXP |
Thapsigargin results in decreased expression of ASF1B mRNA |
CTD |
PMID:22378314 |
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NCBI chr19:14,119,512...14,136,589
Ensembl chr19:14,119,512...14,136,613
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G |
ASGR1 |
asialoglycoprotein receptor 1 |
increases expression |
EXP |
Thapsigargin results in increased expression of ASGR1 mRNA |
CTD |
PMID:29453283 |
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NCBI chr17:7,173,431...7,179,370
Ensembl chr17:7,173,431...7,179,564
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G |
ASNS |
asparagine synthetase (glutamine-hydrolyzing) |
increases expression |
EXP |
Thapsigargin results in increased expression of ASNS mRNA |
CTD |
PMID:22378314 PMID:29453283 |
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NCBI chr 7:97,851,677...97,928,441
Ensembl chr 7:97,851,677...97,872,542
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ASPH |
aspartate beta-hydroxylase |
increases expression |
ISO |
Thapsigargin results in increased expression of ASPH protein |
CTD |
PMID:24648495 |
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NCBI chr 8:61,500,556...61,714,592
Ensembl chr 8:61,500,556...61,714,640
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G |
ATAD2 |
ATPase family AAA domain containing 2 |
decreases expression increases expression |
EXP ISO |
Thapsigargin results in decreased expression of ATAD2 mRNA Thapsigargin results in increased expression of ATAD2 protein |
CTD |
PMID:22378314 PMID:24648495 |
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NCBI chr 8:123,319,850...123,416,350
Ensembl chr 8:123,319,850...123,416,350
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G |
ATF3 |
activating transcription factor 3 |
multiple interactions increases expression |
EXP ISO |
ATF3 mutant form promotes the reaction [Thapsigargin results in increased expression of PMAIP1 mRNA] Thapsigargin results in increased expression of ATF3 mRNA Thapsigargin results in increased expression of ATF3 mRNA; Thapsigargin results in increased expression of ATF3 protein |
CTD |
PMID:17332266 PMID:20022965 PMID:21694771 PMID:22641616 PMID:22935518 PMID:29453283 PMID:33770205 More...
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NCBI chr 1:212,565,407...212,620,777
Ensembl chr 1:212,565,334...212,620,777
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G |
ATF4 |
activating transcription factor 4 |
multiple interactions increases expression increases activity decreases response to substance |
EXP ISO |
2-(4-chlorophenoxy)-N-(4-(2-(4-chlorophenoxy)acetamido)cyclohexyl)acetamide inhibits the reaction [Thapsigargin results in increased expression of ATF4 protein]; ATF4 mutant form inhibits the reaction [Thapsigargin results in increased expression of PMAIP1 mRNA]; ATF4 mutant form inhibits the reaction [Thapsigargin results in increased expression of PMAIP1 protein]; Dactinomycin inhibits the reaction [Thapsigargin results in increased expression of ATF4 mRNA]; Dactinomycin inhibits the reaction [Thapsigargin results in increased expression of ATF4 protein]; Doxorubicin inhibits the reaction [Thapsigargin results in increased expression of ATF4 protein]; NUPR1 mutant form promotes the reaction [Thapsigargin results in increased expression of ATF4 mRNA]; Thapsigargin promotes the reaction [ATF4 protein binds to PMAIP1 promoter] 4-phenylbutyric acid inhibits the reaction [Thapsigargin results in increased expression of ATF4 protein]; salubrinal promotes the reaction [Thapsigargin results in increased expression of ATF4 protein] Thapsigargin results in increased expression of ATF4 mRNA; Thapsigargin results in increased expression of ATF4 protein 2-aminoethoxydiphenyl borate inhibits the reaction [Thapsigargin results in increased expression of ATF4 mRNA]; 2-aminoethoxydiphenyl borate inhibits the reaction [Thapsigargin results in increased expression of ATF4 protein]; 7-methyl-5-(1-((3-(trifluoromethyl)phenyl)acetyl)-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo(2,3-d)pyrimidin-4-amine inhibits the reaction [Thapsigargin results in increased expression of ATF4 protein]; ATF4 gene mutant form inhibits the reaction [Thapsigargin results in increased expression of IBTK mRNA alternative form]; Dantrolene inhibits the reaction [Thapsigargin results in increased expression of ATF4 protein]; Dantrolene promotes the reaction [Thapsigargin results in increased expression of ATF4 mRNA]; EIF2S1 protein modified form affects the reaction [Thapsigargin results in increased expression of ATF4 mRNA]; GSK2656157 inhibits the reaction [Thapsigargin results in increased expression of ATF4 protein] Thapsigargin results in increased activity of ATF4 protein ATF4 results in decreased susceptibility to Thapsigargin |
CTD |
PMID:16298333 PMID:17283163 PMID:20022965 PMID:20589738 PMID:22378314 PMID:23383089 PMID:23741617 PMID:24648495 PMID:24865413 PMID:27226639 PMID:27358234 PMID:27587023 PMID:28223344 PMID:28844859 PMID:29109149 PMID:32357311 PMID:32578922 More...
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NCBI chr22:39,520,559...39,522,686
Ensembl chr22:39,519,695...39,522,686
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G |
ATF5 |
activating transcription factor 5 |
increases expression |
EXP ISO |
Thapsigargin results in increased expression of ATF5 mRNA Thapsigargin results in increased expression of ATF5 mRNA; Thapsigargin results in increased expression of ATF5 protein |
CTD |
PMID:22378314 PMID:24648495 PMID:28942281 |
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NCBI chr19:49,928,906...49,933,935
Ensembl chr19:49,928,702...49,933,935
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G |
ATF6 |
activating transcription factor 6 |
multiple interactions increases cleavage increases expression increases activity |
ISO EXP |
1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea inhibits the reaction [Thapsigargin results in increased expression of ATF6 protein]; Apigenin inhibits the reaction [Thapsigargin results in increased cleavage of ATF6 protein] Thapsigargin results in increased expression of ATF6 mRNA; Thapsigargin results in increased expression of ATF6 protein; Thapsigargin results in increased expression of ATF6 protein modified form 1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea inhibits the reaction [Thapsigargin results in increased expression of ATF6 protein]; ATF6 promotes the reaction [Thapsigargin results in increased expression of DDIT3 protein]; ATF6 promotes the reaction [Thapsigargin results in increased expression of HSPA5 protein]; demethoxycurcumin analog inhibits the reaction [Thapsigargin results in increased expression of ATF6 protein]; Luteolin inhibits the reaction [Thapsigargin results in increased expression of ATF6 protein modified form]; Thapsigargin results in increased cleavage of and affects the localization of ATF6 protein Thapsigargin results in increased activity of ATF6 protein |
CTD |
PMID:17963750 PMID:18477628 PMID:20493918 PMID:22378314 PMID:23383089 PMID:23576437 PMID:23741617 PMID:24638036 PMID:26264395 PMID:27358234 PMID:27587023 PMID:28223344 PMID:30796460 PMID:32407927 More...
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NCBI chr 1:161,766,320...161,964,070
Ensembl chr 1:161,766,298...161,977,574
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ATG10 |
autophagy related 10 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ATG10 protein |
CTD |
PMID:24648495 |
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NCBI chr 5:81,972,023...82,256,133
Ensembl chr 5:81,972,023...82,276,857
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G |
ATP1A1 |
ATPase Na+/K+ transporting subunit alpha 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of ATP1A1 protein |
CTD |
PMID:35544339 |
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NCBI chr 1:116,373,244...116,404,774
Ensembl chr 1:116,372,668...116,410,261
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G |
ATP1B1 |
ATPase Na+/K+ transporting subunit beta 1 |
increases expression |
EXP |
Thapsigargin results in increased expression of ATP1B1 mRNA |
CTD |
PMID:33770205 |
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NCBI chr 1:169,106,690...169,132,719
Ensembl chr 1:169,105,697...169,310,992
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G |
ATP2A2 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 |
affects response to substance increases expression decreases activity multiple interactions |
EXP ISO |
ATP2A2 protein affects the susceptibility to Thapsigargin Thapsigargin results in increased expression of ATP2A2 mRNA; Thapsigargin results in increased expression of ATP2A2 protein Thapsigargin results in decreased activity of ATP2A2 protein [Thapsigargin results in decreased activity of ATP2A2 protein] which results in decreased transport of Calcium; Tetradecanoylphorbol Acetate inhibits the reaction [Thapsigargin results in increased expression of ATP2A2 mRNA]; Thapsigargin results in increased expression of and results in decreased activity of ATP2A2 protein |
CTD |
PMID:17287366 PMID:17475205 PMID:19244478 PMID:20816668 PMID:35544339 |
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NCBI chr12:110,280,616...110,351,093
Ensembl chr12:110,280,756...110,351,093
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G |
ATP2A3 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 |
multiple interactions |
EXP |
[Thapsigargin co-treated with Ionomycin] promotes the reaction [STIM1 protein binds to ATP2A3 protein] |
CTD |
PMID:18439569 |
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NCBI chr17:3,923,873...3,964,437
Ensembl chr17:3,923,868...3,964,464
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G |
ATP2B1 |
ATPase plasma membrane Ca2+ transporting 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ATP2B1 protein |
CTD |
PMID:35544339 |
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NCBI chr12:89,588,049...89,709,366
Ensembl chr12:89,588,049...89,709,366
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G |
ATP2B1-AS1 |
ATP2B1 antisense RNA 1 |
increases expression |
EXP |
Thapsigargin results in increased expression of ATP2B1-AS1 mRNA |
CTD |
PMID:29453283 |
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NCBI chr12:89,708,955...89,711,952
Ensembl chr12:89,708,177...90,143,524
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G |
ATP5F1A |
ATP synthase F1 subunit alpha |
increases expression |
EXP |
Thapsigargin results in increased expression of ATP5F1A mRNA |
CTD |
PMID:22378314 |
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NCBI chr18:46,080,248...46,104,227
Ensembl chr18:46,080,248...46,104,334
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G |
ATP5F1C |
ATP synthase F1 subunit gamma |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ATP5F1C protein |
CTD |
PMID:35544339 |
|
NCBI chr10:7,788,177...7,807,801
Ensembl chr10:7,788,147...7,807,815
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ATP5F1E |
ATP synthase F1 subunit epsilon |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ATP5F1E protein |
CTD |
PMID:35544339 |
|
NCBI chr20:59,025,475...59,032,335
Ensembl chr20:59,025,475...59,032,345
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G |
ATP5MC1 |
ATP synthase membrane subunit c locus 1 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of ATP5MC1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr17:48,892,787...48,895,871
Ensembl chr17:48,892,765...48,895,871
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ATP5MC3 |
ATP synthase membrane subunit c locus 3 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of ATP5MC3 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 2:175,176,258...175,181,710
Ensembl chr 2:175,176,258...175,181,710
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ATP5MF |
ATP synthase membrane subunit f |
decreases expression |
EXP |
Thapsigargin results in decreased expression of ATP5MF mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 7:99,458,195...99,466,167
Ensembl chr 7:99,448,475...99,466,186
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ATP6AP2 |
ATPase H+ transporting accessory protein 2 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ATP6AP2 protein |
CTD |
PMID:35544339 |
|
NCBI chr X:40,580,970...40,606,848
Ensembl chr X:40,579,372...40,606,848
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ATP6V0A1 |
ATPase H+ transporting V0 subunit a1 |
increases expression decreases expression |
EXP ISO |
Thapsigargin results in increased expression of ATP6V0A1 mRNA Thapsigargin results in decreased expression of ATP6V0A1 protein |
CTD |
PMID:29453283 PMID:35544339 |
|
NCBI chr17:42,458,878...42,522,579
Ensembl chr17:42,458,844...42,522,582
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ATP6V0A2 |
ATPase H+ transporting V0 subunit a2 |
increases expression |
EXP |
Thapsigargin results in increased expression of ATP6V0A2 mRNA |
CTD |
PMID:29453283 |
|
NCBI chr12:123,712,353...123,761,755
Ensembl chr12:123,712,353...123,761,755
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G |
ATP6V0D2 |
ATPase H+ transporting V0 subunit d2 |
multiple interactions decreases expression |
EXP |
4-methoxycinnamate methyl ester promotes the reaction [Thapsigargin results in decreased expression of ATP6V0D2 mRNA]; caffeic acid promotes the reaction [Thapsigargin results in decreased expression of ATP6V0D2 mRNA] |
CTD |
PMID:19442820 |
|
NCBI chr 8:86,098,910...86,154,225
Ensembl chr 8:85,987,323...86,154,225
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G |
ATP8A1 |
ATPase phospholipid transporting 8A1 |
increases expression |
ISO |
Thapsigargin results in increased expression of ATP8A1 protein |
CTD |
PMID:24648495 |
|
NCBI chr 4:42,408,373...42,657,105
Ensembl chr 4:42,408,373...42,657,121
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G |
ATP8B1 |
ATPase phospholipid transporting 8B1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ATP8B1 protein |
CTD |
PMID:35544339 |
|
NCBI chr18:57,646,426...57,803,315
Ensembl chr18:57,646,426...57,803,315
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G |
ATRX |
ATRX chromatin remodeler |
increases expression |
ISO |
Thapsigargin results in increased expression of ATRX protein |
CTD |
PMID:24648495 |
|
NCBI chr X:77,504,880...77,786,216
Ensembl chr X:77,504,880...77,786,233
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G |
AUH |
AU RNA binding methylglutaconyl-CoA hydratase |
increases expression |
EXP |
Thapsigargin results in increased expression of AUH mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 9:91,213,823...91,361,918
Ensembl chr 9:91,213,815...91,361,918
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G |
AURKB |
aurora kinase B |
decreases expression |
EXP |
Thapsigargin results in decreased expression of AURKB mRNA |
CTD |
PMID:22378314 |
|
NCBI chr17:8,204,731...8,210,575
Ensembl chr17:8,204,733...8,210,600
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AVEN |
apoptosis and caspase activation inhibitor |
increases expression |
EXP |
Thapsigargin results in increased expression of AVEN mRNA |
CTD |
PMID:29453283 |
|
NCBI chr15:33,851,781...34,075,325
Ensembl chr15:33,858,782...34,075,155
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G |
B4GALT5 |
beta-1,4-galactosyltransferase 5 |
increases expression |
EXP |
Thapsigargin results in increased expression of B4GALT5 mRNA |
CTD |
PMID:29453283 |
|
NCBI chr20:49,632,945...49,713,878
Ensembl chr20:49,632,945...49,713,878
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G |
BACH2 |
BTB domain and CNC homolog 2 |
increases expression |
EXP |
Thapsigargin results in increased expression of BACH2 mRNA |
CTD |
PMID:24247028 |
|
NCBI chr 6:89,926,528...90,296,843
Ensembl chr 6:89,926,528...90,296,843
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G |
BAD |
BCL2 associated agonist of cell death |
increases expression |
EXP |
Thapsigargin results in increased expression of BAD mRNA |
CTD |
PMID:22378314 |
|
NCBI chr11:64,269,828...64,284,704
Ensembl chr11:64,269,830...64,284,704
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G |
BANF1 |
barrier to autointegration nuclear assembly factor 1 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of BANF1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr11:66,002,079...66,004,149
Ensembl chr11:66,002,228...66,004,149
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G |
BASP1 |
brain abundant membrane attached signal protein 1 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of BASP1 mRNA |
CTD |
PMID:22378314 PMID:29453283 |
|
NCBI chr 5:17,216,823...17,276,834
Ensembl chr 5:17,065,598...17,276,843
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G |
BAX |
BCL2 associated X, apoptosis regulator |
increases activity increases expression multiple interactions |
EXP ISO |
Thapsigargin results in increased activity of BAX protein Thapsigargin results in increased expression of BAX protein [Thapsigargin co-treated with dapagliflozin] inhibits the reaction [IL1B protein results in increased expression of BAX protein]; shikonin inhibits the reaction [Thapsigargin results in increased expression of BAX protein] Thapsigargin promotes the reaction [arsenite results in increased expression of BAX protein] |
CTD |
PMID:20130848 PMID:26677073 PMID:35028790 PMID:35033536 PMID:37741535 |
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NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
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G |
BAZ1A |
bromodomain adjacent to zinc finger domain 1A |
increases expression |
ISO |
Thapsigargin results in increased expression of BAZ1A protein |
CTD |
PMID:24648495 |
|
NCBI chr14:34,752,731...34,875,360
Ensembl chr14:34,752,731...34,875,647
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G |
BAZ1B |
bromodomain adjacent to zinc finger domain 1B |
increases expression |
ISO |
Thapsigargin results in increased expression of BAZ1B protein |
CTD |
PMID:24648495 |
|
NCBI chr 7:73,440,406...73,522,293
Ensembl chr 7:73,440,406...73,522,293
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G |
BBC3 |
BCL2 binding component 3 |
increases expression |
ISO EXP |
Thapsigargin results in increased expression of BBC3 mRNA |
CTD |
PMID:16018998 PMID:22378314 |
|
NCBI chr19:47,220,824...47,232,860
Ensembl chr19:47,220,822...47,232,766
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G |
BCAM |
basal cell adhesion molecule (Lutheran blood group) |
decreases expression |
ISO |
Thapsigargin results in decreased expression of BCAM protein |
CTD |
PMID:35544339 |
|
NCBI chr19:44,809,059...44,821,421
Ensembl chr19:44,809,071...44,821,421
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G |
BCAS2 |
BCAS2 pre-mRNA processing factor |
decreases expression |
ISO |
Thapsigargin results in decreased expression of BCAS2 protein |
CTD |
PMID:24648495 |
|
NCBI chr 1:114,567,557...114,581,615
Ensembl chr 1:114,567,557...114,581,629
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G |
BCAT1 |
branched chain amino acid transaminase 1 |
increases expression |
EXP |
Thapsigargin results in increased expression of BCAT1 mRNA |
CTD |
PMID:22378314 PMID:29453283 |
|
NCBI chr12:24,810,024...24,949,340
Ensembl chr12:24,810,024...24,949,101
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G |
BCAT2 |
branched chain amino acid transaminase 2 |
increases expression |
EXP |
Thapsigargin results in increased expression of BCAT2 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr19:48,795,064...48,811,029
Ensembl chr19:48,795,062...48,811,029
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G |
BCKDK |
branched chain keto acid dehydrogenase kinase |
decreases expression |
EXP ISO |
Thapsigargin results in decreased expression of BCKDK mRNA Thapsigargin results in decreased expression of BCKDK protein |
CTD |
PMID:22378314 PMID:24648495 |
|
NCBI chr16:31,108,386...31,117,640
Ensembl chr16:31,106,107...31,112,791
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G |
BCL2 |
BCL2 apoptosis regulator |
increases expression decreases expression multiple interactions |
EXP ISO |
Thapsigargin results in increased expression of BCL2 mRNA Thapsigargin results in decreased expression of BCL2 protein shikonin inhibits the reaction [Thapsigargin results in decreased expression of BCL2 protein] 4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Thapsigargin results in decreased expression of BCL2 protein]; O-1602 compound inhibits the reaction [Thapsigargin results in decreased expression of BCL2 protein] Thapsigargin promotes the reaction [arsenite results in decreased expression of BCL2 protein] |
CTD |
PMID:22378314 PMID:26677073 PMID:30841431 PMID:35028790 PMID:35033536 |
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NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
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G |
BCL2L1 |
BCL2 like 1 |
multiple interactions decreases expression increases expression affects splicing |
ISO EXP |
6-(bromomethylene)tetrahydro-3-(1-naphthaleneyl)-2H-pyran-2-one inhibits the reaction [Thapsigargin affects the splicing of BCL2L1 mRNA]; GW 4869 inhibits the reaction [Thapsigargin affects the splicing of BCL2L1 mRNA]; PLA2G6 mutant form inhibits the reaction [Thapsigargin affects the splicing of BCL2L1 mRNA] Thapsigargin results in decreased expression of BCL2L1 protein 4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Thapsigargin results in decreased expression of BCL2L1 protein]; O-1602 compound inhibits the reaction [Thapsigargin results in decreased expression of BCL2L1 protein] BCL2L1 protein inhibits the reaction [Thapsigargin results in increased expression of ERN1 protein]; BCL2L1 protein inhibits the reaction [Thapsigargin results in increased expression of XBP1 protein alternative form] Thapsigargin results in increased expression of BCL2L1 protein |
CTD |
PMID:23885834 PMID:25762722 PMID:30841431 |
|
NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989
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G |
BCLAF1 |
BCL2 associated transcription factor 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of BCLAF1 protein |
CTD |
PMID:24648495 |
|
NCBI chr 6:136,256,627...136,289,846
Ensembl chr 6:136,256,627...136,289,851
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G |
BEGAIN |
brain enriched guanylate kinase associated |
decreases expression |
EXP |
Thapsigargin results in decreased expression of BEGAIN mRNA |
CTD |
PMID:22378314 |
|
NCBI chr14:100,537,147...100,587,417
Ensembl chr14:100,537,147...100,587,417
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G |
BEND6 |
BEN domain containing 6 |
increases expression |
EXP |
Thapsigargin results in increased expression of BEND6 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 6:56,955,107...57,027,346
Ensembl chr 6:56,955,107...57,027,346
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G |
BEST1 |
bestrophin 1 |
increases expression |
EXP |
Thapsigargin results in increased expression of BEST1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr11:61,949,821...61,965,515
Ensembl chr11:61,950,063...61,965,515
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G |
BET1 |
Bet1 golgi vesicular membrane trafficking protein |
decreases expression multiple interactions |
EXP |
Thapsigargin results in decreased expression of BET1 mRNA [Thapsigargin co-treated with 4-methoxycinnamate methyl ester] results in decreased expression of BET1 mRNA |
CTD |
PMID:19442820 |
|
NCBI chr 7:93,962,762...94,004,355
Ensembl chr 7:93,962,762...94,004,382
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G |
BET1L |
Bet1 golgi vesicular membrane trafficking protein like |
increases expression |
EXP |
Thapsigargin results in increased expression of BET1L mRNA |
CTD |
PMID:22378314 |
|
NCBI chr11:202,924...207,399
Ensembl chr11:167,784...207,399
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G |
BEX2 |
brain expressed X-linked 2 |
increases expression |
EXP |
Thapsigargin results in increased expression of BEX2 mRNA |
CTD |
PMID:29453283 |
|
NCBI chr X:103,309,346...103,310,990
Ensembl chr X:103,309,346...103,311,007
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G |
BHLHE40 |
basic helix-loop-helix family member e40 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of BHLHE40 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 3:4,979,437...4,985,323
Ensembl chr 3:4,979,437...4,985,323
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G |
BID |
BH3 interacting domain death agonist |
decreases expression |
EXP |
Thapsigargin results in decreased expression of BID mRNA |
CTD |
PMID:22378314 |
|
NCBI chr22:17,734,138...17,774,665
Ensembl chr22:17,734,138...17,774,770
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G |
BIN1 |
bridging integrator 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of BIN1 protein |
CTD |
PMID:35544339 |
|
NCBI chr 2:127,048,023...127,107,154
Ensembl chr 2:127,048,027...127,107,288
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G |
BIRC2 |
baculoviral IAP repeat containing 2 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of BIRC2 protein |
CTD |
PMID:16382148 |
|
NCBI chr11:102,347,214...102,378,670
Ensembl chr11:102,347,211...102,378,670
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G |
BIRC3 |
baculoviral IAP repeat containing 3 |
multiple interactions increases expression |
EXP |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Thapsigargin results in increased expression of BIRC3 mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Thapsigargin results in increased expression of BIRC3 protein] Thapsigargin results in increased expression of BIRC3 mRNA; Thapsigargin results in increased expression of BIRC3 protein |
CTD |
PMID:15339911 |
|
NCBI chr11:102,317,484...102,339,403
Ensembl chr11:102,317,484...102,339,403
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G |
BLM |
BLM RecQ like helicase |
increases expression |
ISO |
Thapsigargin results in increased expression of BLM protein |
CTD |
PMID:24648495 |
|
NCBI chr15:90,717,346...90,816,166
Ensembl chr15:90,717,346...90,816,166
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G |
BLNK |
B cell linker |
decreases expression |
ISO |
Thapsigargin results in decreased expression of BLNK protein |
CTD |
PMID:24648495 |
|
NCBI chr10:96,189,171...96,271,569
Ensembl chr10:96,189,171...96,271,587
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G |
BLOC1S2 |
biogenesis of lysosomal organelles complex 1 subunit 2 |
increases expression |
EXP |
Thapsigargin results in increased expression of BLOC1S2 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr10:100,273,278...100,286,680
Ensembl chr10:100,273,280...100,286,680
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G |
BMF |
Bcl2 modifying factor |
decreases expression |
EXP |
Thapsigargin results in decreased expression of BMF mRNA |
CTD |
PMID:33770205 |
|
NCBI chr15:40,087,890...40,108,879
Ensembl chr15:40,087,890...40,108,892
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G |
BMP2K |
BMP2 inducible kinase |
decreases expression |
ISO |
Thapsigargin results in decreased expression of BMP2K protein |
CTD |
PMID:24648495 |
|
NCBI chr 4:78,776,350...78,916,365
Ensembl chr 4:78,776,342...78,916,365
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G |
BMS1 |
BMS1 ribosome biogenesis factor |
increases expression |
ISO |
Thapsigargin results in increased expression of BMS1 protein |
CTD |
PMID:24648495 |
|
NCBI chr10:42,782,795...42,834,937
Ensembl chr10:42,782,795...42,834,937
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G |
BNC2 |
basonuclin zinc finger protein 2 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of BNC2 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 9:16,409,503...16,870,670
Ensembl chr 9:16,409,503...16,870,843
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G |
BNIP3 |
BCL2 interacting protein 3 |
decreases expression |
EXP ISO |
Thapsigargin results in decreased expression of BNIP3 mRNA Thapsigargin results in decreased expression of BNIP3 protein |
CTD |
PMID:22378314 PMID:24648495 |
|
NCBI chr10:131,967,684...131,981,923
Ensembl chr10:131,967,684...131,981,967
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G |
BOLA3 |
bolA family member 3 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of BOLA3 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 2:74,135,400...74,147,912
Ensembl chr 2:74,135,400...74,147,912
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G |
BPHL |
biphenyl hydrolase like |
decreases expression |
EXP |
Thapsigargin results in decreased expression of BPHL mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 6:3,118,376...3,153,578
Ensembl chr 6:3,118,374...3,153,599
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G |
BRCA1 |
BRCA1 DNA repair associated |
increases expression affects localization multiple interactions |
EXP ISO |
Thapsigargin results in increased expression of BRCA1 mRNA; Thapsigargin results in increased expression of BRCA1 protein Thapsigargin affects the localization of BRCA1 mRNA Cycloheximide inhibits the reaction [Thapsigargin affects the localization of BRCA1 mRNA]; Emetine inhibits the reaction [Thapsigargin affects the localization of BRCA1 mRNA] |
CTD |
PMID:16434996 PMID:29576526 |
|
NCBI chr17:43,044,295...43,170,327
Ensembl chr17:43,044,295...43,170,245
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G |
BRCA2 |
BRCA2 DNA repair associated |
increases expression |
EXP |
Thapsigargin results in increased expression of BRCA2 mRNA; Thapsigargin results in increased expression of BRCA2 protein |
CTD |
PMID:16434996 |
|
NCBI chr13:32,315,077...32,400,268
Ensembl chr13:32,315,086...32,400,268
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G |
BRINP1 |
BMP/retinoic acid inducible neural specific 1 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of BRINP1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 9:119,166,629...119,369,435
Ensembl chr 9:119,153,458...119,369,435
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G |
BRIX1 |
biogenesis of ribosomes BRX1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of BRIX1 protein |
CTD |
PMID:35544339 |
|
NCBI chr 5:34,915,711...34,925,996
Ensembl chr 5:34,915,677...34,925,996
|
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G |
BRSK1 |
BR serine/threonine kinase 1 |
increases expression |
EXP |
Thapsigargin results in increased expression of BRSK1 mRNA |
CTD |
PMID:29453283 |
|
NCBI chr19:55,283,997...55,312,562
Ensembl chr19:55,282,072...55,312,562
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G |
BTBD8 |
BTB domain containing 8 |
increases expression |
ISO |
Thapsigargin results in increased expression of BTBD8 protein |
CTD |
PMID:35544339 |
|
NCBI chr 1:92,080,345...92,184,723
Ensembl chr 1:92,080,305...92,184,725
|
|
G |
BUB1B |
BUB1 mitotic checkpoint serine/threonine kinase B |
decreases expression |
EXP |
Thapsigargin results in decreased expression of BUB1B mRNA |
CTD |
PMID:22378314 |
|
NCBI chr15:40,161,069...40,221,123
Ensembl chr15:40,161,023...40,221,123
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G |
BYSL |
bystin like |
increases expression |
ISO |
Thapsigargin results in increased expression of BYSL protein |
CTD |
PMID:35544339 |
|
NCBI chr 6:41,908,759...41,933,046
Ensembl chr 6:41,921,229...41,933,050
|
|
G |
C11orf96 |
chromosome 11 open reading frame 96 |
increases expression |
EXP |
Thapsigargin results in increased expression of C11ORF96 mRNA |
CTD |
PMID:29453283 |
|
NCBI chr11:43,942,637...43,943,878
Ensembl chr11:43,942,637...43,943,878
|
|
G |
C12orf43 |
chromosome 12 open reading frame 43 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of C12H12ORF43 protein |
CTD |
PMID:35544339 |
|
NCBI chr12:121,000,486...121,016,487
Ensembl chr12:121,000,486...121,016,502
|
|
G |
C12orf57 |
chromosome 12 open reading frame 57 |
increases expression |
EXP |
Thapsigargin results in increased expression of C12ORF57 mRNA |
CTD |
PMID:29453283 |
|
NCBI chr12:6,943,433...6,946,003
Ensembl chr12:6,942,978...6,946,003
|
|
G |
C1orf162 |
chromosome 1 open reading frame 162 |
increases expression |
EXP |
Thapsigargin results in increased expression of C1ORF162 mRNA |
CTD |
PMID:29453283 |
|
NCBI chr 1:111,473,984...111,478,512
Ensembl chr 1:111,473,792...111,478,512
|
|
G |
C1QBP |
complement C1q binding protein |
decreases expression |
EXP |
Thapsigargin results in decreased expression of C1QBP mRNA |
CTD |
PMID:22378314 |
|
NCBI chr17:5,432,777...5,439,155
Ensembl chr17:5,432,777...5,448,830
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G |
C5 |
complement C5 |
increases expression |
EXP |
Thapsigargin results in increased expression of C5 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 9:120,952,335...121,074,865
Ensembl chr 9:120,932,987...121,075,195
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G |
C6orf141 |
chromosome 6 open reading frame 141 |
increases expression |
EXP |
Thapsigargin results in increased expression of C6ORF141 mRNA |
CTD |
PMID:29453283 |
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NCBI chr 6:49,550,668...49,561,916
Ensembl chr 6:49,550,666...49,561,907
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G |
CA10 |
carbonic anhydrase 10 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of CA10 mRNA |
CTD |
PMID:22378314 |
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NCBI chr17:51,630,313...52,160,023
Ensembl chr17:51,630,313...52,160,017
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G |
CA5B |
carbonic anhydrase 5B |
increases expression |
EXP |
Thapsigargin results in increased expression of CA5B mRNA |
CTD |
PMID:22378314 |
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NCBI chr X:15,738,270...15,788,411
Ensembl chr X:15,688,830...15,788,411
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G |
CACNA1A |
calcium voltage-gated channel subunit alpha1 A |
increases expression |
EXP |
Thapsigargin results in increased expression of CACNA1A mRNA |
CTD |
PMID:19442820 |
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NCBI chr19:13,206,442...13,506,479
Ensembl chr19:13,206,442...13,624,489
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G |
CACNA2D1 |
calcium voltage-gated channel auxiliary subunit alpha2delta 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CACNA2D1 protein |
CTD |
PMID:24648495 PMID:35544339 |
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NCBI chr 7:81,946,444...82,443,956
Ensembl chr 7:81,946,444...82,443,956
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G |
CACNA2D2 |
calcium voltage-gated channel auxiliary subunit alpha2delta 2 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of CACNA2D2 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 3:50,362,613...50,504,244
Ensembl chr 3:50,362,613...50,504,244
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G |
CACNG4 |
calcium voltage-gated channel auxiliary subunit gamma 4 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of CACNG4 mRNA |
CTD |
PMID:22378314 |
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NCBI chr17:66,964,707...67,033,398
Ensembl chr17:66,964,707...67,033,398
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G |
CADM1 |
cell adhesion molecule 1 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of CADM1 mRNA |
CTD |
PMID:29453283 |
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NCBI chr11:115,169,236...115,504,415
Ensembl chr11:115,169,218...115,504,957
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G |
CALCA |
calcitonin related polypeptide alpha |
multiple interactions |
EXP |
Thapsigargin promotes the reaction [Lipopolysaccharides results in increased expression of CALCA mRNA] |
CTD |
PMID:20682585 |
|
NCBI chr11:14,966,668...14,972,351
Ensembl chr11:14,966,622...14,972,354
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G |
CALCB |
calcitonin related polypeptide beta |
increases expression |
EXP |
Thapsigargin results in increased expression of CALCB mRNA |
CTD |
PMID:29453283 |
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NCBI chr11:15,073,593...15,078,637
Ensembl chr11:14,904,997...15,082,342
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G |
CALR |
calreticulin |
increases expression |
EXP ISO |
Thapsigargin results in increased expression of CALR mRNA; Thapsigargin results in increased expression of CALR protein |
CTD |
PMID:17353921 PMID:22378314 PMID:27587023 PMID:29453283 PMID:35544339 |
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NCBI chr19:12,938,609...12,944,489
Ensembl chr19:12,938,578...12,944,489
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G |
CALU |
calumenin |
decreases expression increases expression |
EXP ISO |
Thapsigargin results in decreased expression of CALU mRNA; Thapsigargin results in decreased expression of CALU protein Thapsigargin results in increased expression of CALU mRNA |
CTD |
PMID:21692457 PMID:22378314 PMID:35544339 |
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NCBI chr 7:128,739,359...128,773,400
Ensembl chr 7:128,739,292...128,773,400
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G |
CAMK4 |
calcium/calmodulin dependent protein kinase IV |
multiple interactions |
ISO |
Thapsigargin inhibits the reaction [LIF protein results in increased activity of CAMK4 protein] |
CTD |
PMID:11073891 |
|
NCBI chr 5:111,223,583...111,494,886
Ensembl chr 5:111,223,653...111,494,886
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G |
CANX |
calnexin |
increases expression affects localization |
EXP ISO |
Thapsigargin results in increased expression of CANX mRNA; Thapsigargin results in increased expression of CANX protein Thapsigargin affects the localization of CANX protein |
CTD |
PMID:17353921 PMID:22378314 PMID:28315715 PMID:28940366 PMID:29453283 PMID:35544339 More...
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NCBI chr 5:179,678,656...179,731,641
Ensembl chr 5:179,678,628...179,731,641
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G |
CAPN1 |
calpain 1 |
increases expression multiple interactions |
ISO |
Thapsigargin results in increased expression of CAPN1 protein Thapsigargin promotes the reaction [cadmium acetate results in increased expression of CAPN1 protein] |
CTD |
PMID:28347754 |
|
NCBI chr11:65,181,373...65,212,006
Ensembl chr11:65,180,566...65,212,006
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G |
CAPZB |
capping actin protein of muscle Z-line subunit beta |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CAPZB protein |
CTD |
PMID:35544339 |
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NCBI chr 1:19,338,775...19,485,539
Ensembl chr 1:19,338,775...19,485,539
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G |
CARD9 |
caspase recruitment domain family member 9 |
increases expression |
EXP |
Thapsigargin results in increased expression of CARD9 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 9:136,363,956...136,373,669
Ensembl chr 9:136,363,956...136,373,681
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G |
CARHSP1 |
calcium regulated heat stable protein 1 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of CARHSP1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr16:8,852,942...8,869,006
Ensembl chr16:8,852,942...8,869,012
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G |
CASP1 |
caspase 1 |
increases expression |
EXP |
Thapsigargin results in increased expression of CASP1 mRNA |
CTD |
PMID:30796460 |
|
NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250
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G |
CASP12 |
caspase 12 (gene/pseudogene) |
multiple interactions increases expression increases activity increases cleavage |
EXP ISO |
demethoxycurcumin analog inhibits the reaction [Thapsigargin results in increased expression of CASP12 protein modified form]; Resveratrol inhibits the reaction [Thapsigargin results in increased activity of CASP12 protein]; ursodoxicoltaurine inhibits the reaction [Thapsigargin results in increased cleavage of CASP12 protein] 4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Thapsigargin results in increased expression of CASP12 protein modified form]; Apigenin inhibits the reaction [Thapsigargin results in increased activity of CASP12 protein]; O-1602 compound inhibits the reaction [Thapsigargin results in increased expression of CASP12 protein modified form]; Thapsigargin promotes the reaction [Arsenic Trioxide results in increased expression of CASP12 protein modified form] Thapsigargin results in increased cleavage of CASP12 protein alternative form |
CTD |
PMID:12198651 PMID:16338971 PMID:18477628 PMID:20493918 PMID:24224909 PMID:26264395 PMID:27638049 PMID:30841431 More...
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NCBI chr11:104,883,286...104,898,460
Ensembl chr11:104,885,718...104,898,670
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G |
CASP2 |
caspase 2 |
multiple interactions increases activity |
EXP |
Diclofenac inhibits the reaction [Thapsigargin results in increased activity of CASP2 protein] |
CTD |
PMID:16388830 |
|
NCBI chr 7:143,288,351...143,307,696
Ensembl chr 7:143,288,215...143,307,696
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G |
CASP3 |
caspase 3 |
multiple interactions increases expression increases cleavage increases activity increases metabolic processing |
EXP ISO |
1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea inhibits the reaction [Thapsigargin results in increased expression of CASP3 protein]; Bortezomib promotes the reaction [Thapsigargin results in increased activity of CASP3 protein]; Cyclosporine inhibits the reaction [Thapsigargin results in increased activity of CASP3 protein]; Diclofenac inhibits the reaction [Thapsigargin results in increased activity of CASP3 protein]; Melatonin inhibits the reaction [Thapsigargin results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [Thapsigargin results in increased activity of CASP3 protein]; Thapsigargin promotes the reaction [pterostilbene results in increased activity of CASP3 protein]; ursodoxicoltaurine inhibits the reaction [Thapsigargin results in increased activity of CASP3 protein] Thapsigargin results in increased cleavage of CASP3 protein 1-Deoxynojirimycin inhibits the reaction [Thapsigargin results in increased activity of CASP3 protein] 1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea inhibits the reaction [Thapsigargin results in increased expression of CASP3 protein]; 4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Thapsigargin results in increased cleavage of CASP3 protein]; Apigenin inhibits the reaction [Thapsigargin results in increased activity of CASP3 protein]; HR protein affects the reaction [Thapsigargin results in increased activity of CASP3 protein]; O-1602 compound inhibits the reaction [Thapsigargin results in increased cleavage of CASP3 protein]; Thapsigargin promotes the reaction [Arsenic Trioxide results in increased expression of CASP3 protein modified form] Thapsigargin results in increased metabolism of CASP3 protein Thapsigargin results in increased expression of CASP3 protein; Thapsigargin results in increased expression of CASP3 protein alternative form |
CTD |
PMID:12198651 PMID:12871656 PMID:16338971 PMID:16357177 PMID:16382148 PMID:16388830 PMID:17559149 PMID:18178165 PMID:19028522 PMID:20022965 PMID:20130848 PMID:20493918 PMID:20886113 PMID:22800509 PMID:23576437 PMID:25341683 PMID:27638049 PMID:30841431 More...
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NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
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G |
CASP4 |
caspase 4 |
multiple interactions |
EXP |
Thapsigargin promotes the reaction [pterostilbene results in increased activity of CASP4 protein]; Thapsigargin results in increased cleavage of and results in increased activity of CASP4 protein |
CTD |
PMID:17559149 PMID:25341683 |
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NCBI chr11:104,942,866...104,968,574
Ensembl chr11:104,942,866...104,969,366
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G |
CASP6 |
caspase 6 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CASP6 protein |
CTD |
PMID:24648495 |
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NCBI chr 4:109,664,388...109,709,767
Ensembl chr 4:109,688,622...109,703,583
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G |
CASP7 |
caspase 7 |
multiple interactions increases activity |
EXP |
Doxorubicin inhibits the reaction [Thapsigargin results in increased activity of and results in increased cleavage of CASP7 protein]; Thapsigargin results in increased activity of and results in increased cleavage of CASP7 protein; ursodoxicoltaurine inhibits the reaction [Thapsigargin results in increased activity of CASP7 protein] |
CTD |
PMID:12198651 PMID:16298333 PMID:17559149 PMID:19139269 PMID:20022965 |
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NCBI chr10:113,679,194...113,730,909
Ensembl chr10:113,679,162...113,730,907
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G |
CASP8 |
caspase 8 |
increases activity |
ISO |
Thapsigargin results in increased activity of CASP8 protein |
CTD |
PMID:16018998 |
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NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836
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G |
CASP9 |
caspase 9 |
multiple interactions increases cleavage increases activity |
EXP ISO |
Diclofenac inhibits the reaction [Thapsigargin results in increased activity of CASP9 protein]; Melatonin inhibits the reaction [Thapsigargin results in increased activity of CASP9 protein]; Thapsigargin promotes the reaction [pterostilbene results in increased activity of CASP9 protein] 4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Thapsigargin results in increased cleavage of CASP9 protein]; O-1602 compound inhibits the reaction [Thapsigargin results in increased cleavage of CASP9 protein] |
CTD |
PMID:16018998 PMID:16388830 PMID:20130848 PMID:25341683 PMID:30841431 |
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NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
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G |
CASR |
calcium sensing receptor |
multiple interactions |
ISO |
Thapsigargin inhibits the reaction [Spermine binds to and results in increased activity of CASR protein] |
CTD |
PMID:11071898 |
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NCBI chr 3:122,183,668...122,291,629
Ensembl chr 3:122,183,668...122,291,629
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G |
CAT |
catalase |
increases expression |
ISO |
Thapsigargin results in increased expression of CAT protein |
CTD |
PMID:35544339 |
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NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
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G |
CATSPER2 |
cation channel sperm associated 2 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of CATSPER2 mRNA |
CTD |
PMID:19442820 |
|
NCBI chr15:43,628,503...43,648,884
Ensembl chr15:43,628,503...43,668,118
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G |
CBLN2 |
cerebellin 2 precursor |
decreases expression |
EXP |
Thapsigargin results in decreased expression of CBLN2 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr18:72,536,681...72,638,521
Ensembl chr18:72,536,680...72,638,521
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G |
CBR1 |
carbonyl reductase 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of CBR1 protein |
CTD |
PMID:35544339 |
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NCBI chr21:36,070,024...36,073,164
Ensembl chr21:36,069,941...36,073,166
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G |
CC2D1A |
coiled-coil and C2 domain containing 1A |
increases expression |
ISO |
Thapsigargin results in increased expression of CC2D1A protein |
CTD |
PMID:35544339 |
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NCBI chr19:13,906,201...13,930,879
Ensembl chr19:13,906,201...13,930,879
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G |
CCDC171 |
coiled-coil domain containing 171 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of CCDC171 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 9:15,552,885...16,108,926
Ensembl chr 9:15,553,043...16,061,663
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G |
CCDC47 |
coiled-coil domain containing 47 |
increases expression |
ISO |
Thapsigargin results in increased expression of CCDC47 protein |
CTD |
PMID:35544339 |
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NCBI chr17:63,745,255...63,773,597
Ensembl chr17:63,745,255...63,776,351
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G |
CCDC61 |
coiled-coil domain containing 61 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CCDC61 protein |
CTD |
PMID:35544339 |
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NCBI chr19:45,995,467...46,018,616
Ensembl chr19:45,995,461...46,021,318
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G |
CCDC74B |
coiled-coil domain containing 74B |
increases expression |
EXP |
Thapsigargin results in increased expression of CCDC74B mRNA |
CTD |
PMID:22378314 |
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NCBI chr 2:130,139,287...130,145,112
Ensembl chr 2:130,139,287...130,145,134
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G |
CCL2 |
C-C motif chemokine ligand 2 |
increases expression decreases expression multiple interactions |
EXP ISO |
Thapsigargin results in increased expression of CCL2 mRNA Thapsigargin results in decreased expression of CCL2 mRNA Thapsigargin inhibits the reaction [IL1B protein results in increased expression of CCL2 mRNA]; Thapsigargin inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA] |
CTD |
PMID:8764118 PMID:18799549 PMID:18951912 PMID:20830808 |
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NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208
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G |
CCL3 |
C-C motif chemokine ligand 3 |
increases expression |
ISO |
Thapsigargin results in increased expression of CCL3 mRNA; Thapsigargin results in increased expression of CCL3 protein |
CTD |
PMID:20830808 |
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NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169
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G |
CCN1 |
cellular communication network factor 1 |
increases expression |
EXP |
Thapsigargin results in increased expression of CCN1 mRNA |
CTD |
PMID:29453283 |
|
NCBI chr 1:85,580,761...85,583,950
Ensembl chr 1:85,580,761...85,584,589
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G |
CCNA2 |
cyclin A2 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of CCNA2 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 4:121,816,444...121,823,883
Ensembl chr 4:121,816,444...121,823,883
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G |
CCNB1 |
cyclin B1 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of CCNB1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 5:69,167,150...69,178,245
Ensembl chr 5:69,167,135...69,178,245
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G |
CCNB1IP1 |
cyclin B1 interacting protein 1 |
increases expression |
EXP |
Thapsigargin results in increased expression of CCNB1IP1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr14:20,311,370...20,333,279
Ensembl chr14:20,311,368...20,333,312
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G |
CCND1 |
cyclin D1 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of CCND1 mRNA |
CTD |
PMID:17332266 PMID:22378314 |
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NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
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G |
CCNF |
cyclin F |
decreases expression |
EXP |
Thapsigargin results in decreased expression of CCNF mRNA |
CTD |
PMID:22378314 |
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NCBI chr16:2,429,447...2,458,854
Ensembl chr16:2,429,394...2,458,854
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G |
CCNG2 |
cyclin G2 |
increases expression |
EXP |
Thapsigargin results in increased expression of CCNG2 mRNA |
CTD |
PMID:17332266 |
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NCBI chr 4:77,157,207...77,170,060
Ensembl chr 4:77,157,207...77,433,388
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G |
CCNQ |
cyclin Q |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CCNQ protein |
CTD |
PMID:24648495 |
|
NCBI chr X:153,587,925...153,599,139
Ensembl chr X:153,587,925...153,600,045
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G |
CCPG1 |
cell cycle progression 1 |
increases expression |
EXP |
Thapsigargin results in increased expression of CCPG1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr15:55,355,239...55,408,359
Ensembl chr15:55,340,032...55,408,510
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G |
CD2AP |
CD2 associated protein |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CD2AP protein |
CTD |
PMID:35544339 |
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NCBI chr 6:47,477,789...47,627,263
Ensembl chr 6:47,477,789...47,627,263
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G |
CD44 |
CD44 molecule (IN blood group) |
increases expression |
EXP |
Thapsigargin results in increased expression of CD44 mRNA |
CTD |
PMID:29453283 |
|
NCBI chr11:35,139,171...35,232,402
Ensembl chr11:35,138,882...35,232,402
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G |
CD55 |
CD55 molecule (Cromer blood group) |
increases expression |
EXP |
Thapsigargin results in increased expression of CD55 mRNA |
CTD |
PMID:24247028 |
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NCBI chr 1:207,321,678...207,360,966
Ensembl chr 1:207,321,519...207,386,804
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CD69 |
CD69 molecule |
increases expression |
EXP |
Thapsigargin results in increased expression of CD69 mRNA |
CTD |
PMID:24247028 |
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NCBI chr12:9,752,486...9,760,901
Ensembl chr12:9,752,486...9,760,901
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G |
CD70 |
CD70 molecule |
increases expression |
EXP |
Thapsigargin results in increased expression of CD70 mRNA |
CTD |
PMID:29453283 |
|
NCBI chr19:6,581,648...6,591,150
Ensembl chr19:6,583,183...6,604,103
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G |
CDC20 |
cell division cycle 20 |
multiple interactions increases expression |
EXP |
[Thapsigargin co-treated with 4-methoxycinnamate methyl ester] results in increased expression of CDC20 mRNA; [Thapsigargin co-treated with caffeic acid] results in increased expression of CDC20 mRNA; [Thapsigargin co-treated with Drugs, Chinese Herbal] results in increased expression of CDC20 mRNA Thapsigargin results in increased expression of CDC20 mRNA |
CTD |
PMID:19442820 |
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NCBI chr 1:43,358,981...43,363,203
Ensembl chr 1:43,358,981...43,363,203
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G |
CDC45 |
cell division cycle 45 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of CDC45 mRNA |
CTD |
PMID:22378314 |
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NCBI chr22:19,479,466...19,520,612
Ensembl chr22:19,479,457...19,520,612
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G |
CDC5L |
cell division cycle 5 like |
increases expression |
ISO |
Thapsigargin results in increased expression of CDC5L protein |
CTD |
PMID:24648495 |
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NCBI chr 6:44,387,706...44,450,425
Ensembl chr 6:44,387,706...44,450,425
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G |
CDC7 |
cell division cycle 7 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of CDC7 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 1:91,500,851...91,525,764
Ensembl chr 1:91,500,851...91,525,764
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G |
CDC73 |
cell division cycle 73 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CDC73 protein |
CTD |
PMID:35544339 |
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NCBI chr 1:193,122,031...193,254,815
Ensembl chr 1:193,121,983...193,254,815
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G |
CDCA2 |
cell division cycle associated 2 |
increases expression |
ISO |
Thapsigargin results in increased expression of CDCA2 protein |
CTD |
PMID:24648495 |
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NCBI chr 8:25,458,931...25,507,917
Ensembl chr 8:25,459,199...25,507,911
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G |
CDCA7 |
cell division cycle associated 7 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of CDCA7 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 2:173,354,872...173,368,997
Ensembl chr 2:173,354,820...173,368,997
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G |
CDCA7L |
cell division cycle associated 7 like |
decreases expression |
EXP |
Thapsigargin results in decreased expression of CDCA7L mRNA |
CTD |
PMID:22378314 |
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NCBI chr 7:21,900,899...21,945,899
Ensembl chr 7:21,900,899...21,945,903
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G |
CDH15 |
cadherin 15 |
increases expression |
EXP |
Thapsigargin results in increased expression of CDH15 mRNA |
CTD |
PMID:22378314 |
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NCBI chr16:89,171,748...89,195,492
Ensembl chr16:89,171,748...89,195,492
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G |
CDIPT |
CDP-diacylglycerol--inositol 3-phosphatidyltransferase |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CDIPT protein |
CTD |
PMID:24648495 |
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NCBI chr16:29,858,357...29,863,226
Ensembl chr16:29,858,357...29,863,414
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G |
CDK1 |
cyclin dependent kinase 1 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of CDK1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr10:60,778,331...60,794,852
Ensembl chr10:60,778,331...60,794,852
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G |
CDK2 |
cyclin dependent kinase 2 |
multiple interactions decreases expression increases expression |
EXP |
4-methoxycinnamate methyl ester promotes the reaction [Thapsigargin results in increased expression of CDK2 mRNA]; caffeic acid promotes the reaction [Thapsigargin results in increased expression of CDK2 mRNA]; Drugs, Chinese Herbal promotes the reaction [Thapsigargin results in increased expression of CDK2 mRNA] Thapsigargin results in decreased expression of CDK2 mRNA |
CTD |
PMID:19442820 PMID:22378314 |
|
NCBI chr12:55,966,830...55,972,789
Ensembl chr12:55,966,781...55,972,789
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|
G |
CDK2AP2 |
cyclin dependent kinase 2 associated protein 2 |
increases expression |
EXP |
Thapsigargin results in increased expression of CDK2AP2 mRNA |
CTD |
PMID:22378314 PMID:29453283 |
|
NCBI chr11:67,506,497...67,508,162
Ensembl chr11:67,506,497...67,508,649
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G |
CDK5RAP2 |
CDK5 regulatory subunit associated protein 2 |
increases expression |
ISO |
Thapsigargin results in increased expression of CDK5RAP2 protein |
CTD |
PMID:24648495 |
|
NCBI chr 9:120,388,875...120,580,167
Ensembl chr 9:120,388,875...120,580,170
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|
G |
CDK5RAP3 |
CDK5 regulatory subunit associated protein 3 |
increases expression |
EXP ISO |
Thapsigargin results in increased expression of CDK5RAP3 mRNA Thapsigargin results in increased expression of CDK5RAP3 protein |
CTD |
PMID:29453283 PMID:35544339 |
|
NCBI chr17:47,967,904...47,981,781
Ensembl chr17:47,967,810...47,981,781
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G |
CDK7 |
cyclin dependent kinase 7 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CDK7 protein |
CTD |
PMID:24648495 |
|
NCBI chr 5:69,234,795...69,277,430
Ensembl chr 5:69,234,795...69,277,430
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|
G |
CDKN1A |
cyclin dependent kinase inhibitor 1A |
increases expression |
EXP |
Thapsigargin results in increased expression of CDKN1A mRNA |
CTD |
PMID:29453283 PMID:33770205 |
|
NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,397
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|
G |
CDR2 |
cerebellar degeneration related protein 2 |
increases expression |
EXP |
Thapsigargin results in increased expression of CDR2 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr16:22,345,936...22,374,619
Ensembl chr16:22,345,936...22,437,165
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|
G |
CEBPB |
CCAAT enhancer binding protein beta |
increases expression multiple interactions |
EXP |
Thapsigargin results in increased expression of CEBPB mRNA; Thapsigargin results in increased expression of CEBPB protein alternative form Thapsigargin promotes the reaction [CEBPB protein binds to NR1I2 promoter] |
CTD |
PMID:22378314 PMID:25616597 PMID:29453283 |
|
NCBI chr20:50,190,583...50,192,690
Ensembl chr20:50,190,734...50,192,690
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|
G |
CEBPE |
CCAAT enhancer binding protein epsilon |
increases expression |
EXP |
Thapsigargin results in increased expression of CEBPE mRNA |
CTD |
PMID:29453283 |
|
NCBI chr14:23,117,306...23,119,255
Ensembl chr14:23,117,036...23,120,256
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G |
CEBPG |
CCAAT enhancer binding protein gamma |
increases expression |
EXP |
Thapsigargin results in increased expression of CEBPG mRNA |
CTD |
PMID:22378314 PMID:29453283 |
|
NCBI chr19:33,373,709...33,382,686
Ensembl chr19:33,373,685...33,382,686
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G |
CENPA |
centromere protein A |
decreases expression |
EXP |
Thapsigargin results in decreased expression of CENPA mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 2:26,786,056...26,794,589
Ensembl chr 2:26,764,289...26,801,067
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G |
CENPF |
centromere protein F |
increases expression |
EXP |
Thapsigargin results in increased expression of CENPF mRNA |
CTD |
PMID:19442820 |
|
NCBI chr 1:214,603,195...214,664,571
Ensembl chr 1:214,603,185...214,664,574
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G |
CENPU |
centromere protein U |
decreases expression |
EXP |
Thapsigargin results in decreased expression of CENPU mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 4:184,694,085...184,734,096
Ensembl chr 4:184,694,085...184,734,130
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G |
CEP290 |
centrosomal protein 290 |
increases expression |
ISO |
Thapsigargin results in increased expression of CEP290 protein |
CTD |
PMID:24648495 |
|
NCBI chr12:88,049,016...88,142,088
Ensembl chr12:88,049,016...88,142,099
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G |
CES5A |
carboxylesterase 5A |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CES5A protein |
CTD |
PMID:24648495 |
|
NCBI chr16:55,846,154...55,956,031
Ensembl chr16:55,846,154...55,956,031
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G |
CETN2 |
centrin 2 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CETN2 protein |
CTD |
PMID:24648495 |
|
NCBI chr X:152,826,994...152,830,757
Ensembl chr X:152,826,994...152,830,757
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|
G |
CFL1 |
cofilin 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CFL1 protein |
CTD |
PMID:35544339 |
|
NCBI chr11:65,854,673...65,858,180
Ensembl chr11:65,823,022...65,862,026
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|
G |
CFTR |
CF transmembrane conductance regulator |
multiple interactions |
EXP |
Thapsigargin promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; Thapsigargin promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium results in increased activity of CFTR protein mutant form]; Thapsigargin promotes the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; Thapsigargin promotes the reaction [miglustat results in increased activity of CFTR protein mutant form] |
CTD |
PMID:18230692 |
|
NCBI chr 7:117,480,025...117,668,665
Ensembl chr 7:117,287,120...117,715,971
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G |
CGA |
glycoprotein hormones, alpha polypeptide |
increases expression |
EXP |
Thapsigargin results in increased expression of CGA mRNA |
CTD |
PMID:21694771 PMID:29453283 |
|
NCBI chr 6:87,085,498...87,095,106
Ensembl chr 6:87,085,498...87,095,106
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|
G |
CGN |
cingulin |
decreases expression |
EXP |
Thapsigargin results in decreased expression of CGN mRNA |
CTD |
PMID:29453283 |
|
NCBI chr 1:151,510,170...151,538,692
Ensembl chr 1:151,510,510...151,538,692
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G |
CGNL1 |
cingulin like 1 |
increases expression decreases expression |
ISO EXP |
Thapsigargin results in increased expression of CGNL1 protein Thapsigargin results in decreased expression of CGNL1 mRNA |
CTD |
PMID:24648495 PMID:29453283 |
|
NCBI chr15:57,376,505...57,550,717
Ensembl chr15:57,375,967...57,550,717
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G |
CHAC1 |
ChaC glutathione specific gamma-glutamylcyclotransferase 1 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of CHAC1 mRNA |
CTD |
PMID:19442820 |
|
NCBI chr15:40,953,471...40,956,512
Ensembl chr15:40,952,962...40,956,512
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|
G |
CHAF1A |
chromatin assembly factor 1 subunit A |
increases expression decreases expression |
EXP |
Thapsigargin results in increased expression of CHAF1A mRNA Thapsigargin results in decreased expression of CHAF1A mRNA |
CTD |
PMID:19442820 PMID:22378314 |
|
NCBI chr19:4,402,640...4,450,830
Ensembl chr19:4,402,640...4,445,018
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G |
CHAF1B |
chromatin assembly factor 1 subunit B |
decreases expression |
EXP |
Thapsigargin results in decreased expression of CHAF1B mRNA |
CTD |
PMID:22378314 |
|
NCBI chr21:36,385,392...36,419,015
Ensembl chr21:36,385,392...36,419,015
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G |
CHCHD6 |
coiled-coil-helix-coiled-coil-helix domain containing 6 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CHCHD6 protein |
CTD |
PMID:24648495 |
|
NCBI chr 3:126,704,240...126,960,420
Ensembl chr 3:126,704,240...126,960,420
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G |
CHCHD7 |
coiled-coil-helix-coiled-coil-helix domain containing 7 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CHCHD7 protein |
CTD |
PMID:24648495 |
|
NCBI chr 8:56,211,789...56,218,809
Ensembl chr 8:56,211,686...56,218,809
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G |
CHD4 |
chromodomain helicase DNA binding protein 4 |
increases expression |
ISO |
Thapsigargin results in increased expression of CHD4 protein |
CTD |
PMID:24648495 |
|
NCBI chr12:6,570,082...6,607,379
Ensembl chr12:6,570,082...6,614,524
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G |
CHEK1 |
checkpoint kinase 1 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of CHEK1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr11:125,625,136...125,681,124
Ensembl chr11:125,625,163...125,676,255
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|
G |
CHGA |
chromogranin A |
decreases expression increases expression |
EXP ISO |
Thapsigargin results in decreased expression of CHGA mRNA Thapsigargin results in increased expression of CHGA protein Thapsigargin results in increased expression of CHGA mRNA |
CTD |
PMID:22378314 PMID:29453283 PMID:35544339 |
|
NCBI chr14:92,922,664...92,935,285
Ensembl chr14:92,923,150...92,935,285
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G |
CHGB |
chromogranin B |
increases expression |
ISO |
Thapsigargin results in increased expression of CHGB protein |
CTD |
PMID:35544339 |
|
NCBI chr20:5,911,510...5,925,353
Ensembl chr20:5,911,510...5,925,353
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|
G |
CHID1 |
chitinase domain containing 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CHID1 protein |
CTD |
PMID:24648495 PMID:35544339 |
|
NCBI chr11:867,859...915,214
Ensembl chr11:867,859...915,058
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|
G |
CHKB |
choline kinase beta |
increases expression |
ISO |
Thapsigargin results in increased expression of CHKB protein |
CTD |
PMID:35544339 |
|
NCBI chr22:50,578,963...50,582,849
Ensembl chr22:50,578,959...50,601,455
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G |
CHPF |
chondroitin polymerizing factor |
increases expression |
EXP |
Thapsigargin results in increased expression of CHPF mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 2:219,538,954...219,543,809
Ensembl chr 2:219,538,954...219,543,809
|
|
G |
CHPT1 |
choline phosphotransferase 1 |
increases expression |
EXP |
Thapsigargin results in increased expression of CHPT1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr12:101,697,640...101,729,074
Ensembl chr12:101,696,947...101,744,140
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|
G |
CHRM1 |
cholinergic receptor muscarinic 1 |
multiple interactions |
ISO |
Thapsigargin inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium] |
CTD |
PMID:18316702 |
|
NCBI chr11:62,908,679...62,921,878
Ensembl chr11:62,908,679...62,921,807
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|
G |
CHRNA3 |
cholinergic receptor nicotinic alpha 3 subunit |
decreases expression |
EXP |
Thapsigargin results in decreased expression of CHRNA3 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr15:78,593,052...78,620,996
Ensembl chr15:78,593,052...78,621,295
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G |
CHRNA5 |
cholinergic receptor nicotinic alpha 5 subunit |
decreases expression |
EXP |
Thapsigargin results in decreased expression of CHRNA5 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr15:78,565,520...78,595,269
Ensembl chr15:78,565,520...78,595,269
|
|
G |
CHRNB4 |
cholinergic receptor nicotinic beta 4 subunit |
decreases expression |
EXP |
Thapsigargin results in decreased expression of CHRNB4 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr15:78,624,111...78,661,641
Ensembl chr15:78,624,111...78,727,754
|
|
G |
CHST15 |
carbohydrate sulfotransferase 15 |
increases expression |
EXP |
Thapsigargin results in increased expression of CHST15 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr10:124,007,668...124,093,598
Ensembl chr10:124,007,668...124,093,598
|
|
G |
CIAPIN1 |
cytokine induced apoptosis inhibitor 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of CIAPIN1 protein |
CTD |
PMID:35544339 |
|
NCBI chr16:57,428,187...57,447,385
Ensembl chr16:57,428,187...57,447,420
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|
G |
CIRBP |
cold inducible RNA binding protein |
increases expression |
EXP |
Thapsigargin results in increased expression of CIRBP mRNA |
CTD |
PMID:29453283 |
|
NCBI chr19:1,269,332...1,274,880
Ensembl chr19:1,259,384...1,274,880
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G |
CKAP5 |
cytoskeleton associated protein 5 |
increases expression |
ISO |
Thapsigargin results in increased expression of CKAP5 protein |
CTD |
PMID:24648495 |
|
NCBI chr11:46,743,048...46,846,280
Ensembl chr11:46,743,048...46,846,308
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|
G |
CKB |
creatine kinase B |
decreases expression |
EXP |
Thapsigargin results in decreased expression of CKB mRNA; Thapsigargin results in decreased expression of CKB protein |
CTD |
PMID:21692457 PMID:22378314 |
|
NCBI chr14:103,519,667...103,522,830
Ensembl chr14:103,519,667...103,522,833
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G |
CLCC1 |
chloride channel CLIC like 1 |
increases expression |
EXP |
Thapsigargin results in increased expression of CLCC1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 1:108,929,505...108,963,484
Ensembl chr 1:108,881,885...108,963,527
|
|
G |
CLEC11A |
C-type lectin domain containing 11A |
increases expression |
EXP |
Thapsigargin results in increased expression of CLEC11A mRNA |
CTD |
PMID:19442820 |
|
NCBI chr19:50,723,364...50,725,708
Ensembl chr19:50,723,364...50,725,708
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|
G |
CLIP2 |
CAP-Gly domain containing linker protein 2 |
increases expression |
ISO |
Thapsigargin results in increased expression of CLIP2 protein |
CTD |
PMID:35544339 |
|
NCBI chr 7:74,289,407...74,405,935
Ensembl chr 7:74,289,407...74,405,935
|
|
G |
CLN8 |
CLN8 transmembrane ER and ERGIC protein |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CLN8 protein |
CTD |
PMID:24648495 |
|
NCBI chr 8:1,753,059...1,786,570
Ensembl chr 8:1,755,778...1,801,711
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|
G |
CLPB |
ClpB family mitochondrial disaggregase |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CLPB protein |
CTD |
PMID:35544339 |
|
NCBI chr11:72,285,495...72,434,531
Ensembl chr11:72,285,495...72,434,680
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|
G |
CLPP |
caseinolytic mitochondrial matrix peptidase proteolytic subunit |
increases expression |
EXP |
Thapsigargin results in increased expression of CLPP mRNA |
CTD |
PMID:22378314 |
|
NCBI chr19:6,361,531...6,370,242
Ensembl chr19:6,361,427...6,370,242
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|
G |
CLTB |
clathrin light chain B |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CLTB protein |
CTD |
PMID:35544339 |
|
NCBI chr 5:176,392,455...176,416,569
Ensembl chr 5:176,392,501...176,416,539
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G |
CLTC |
clathrin heavy chain |
increases expression |
ISO |
Thapsigargin results in increased expression of CLTC protein |
CTD |
PMID:24648495 |
|
NCBI chr17:59,619,895...59,696,956
Ensembl chr17:59,619,680...59,696,956
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G |
CMBL |
carboxymethylenebutenolidase homolog |
increases expression |
ISO |
Thapsigargin results in increased expression of CMBL protein |
CTD |
PMID:35544339 |
|
NCBI chr 5:10,277,595...10,307,902
Ensembl chr 5:10,275,875...10,307,902
|
|
G |
CNDP2 |
carnosine dipeptidase 2 |
increases expression |
ISO |
Thapsigargin results in increased expression of CNDP2 protein |
CTD |
PMID:35544339 |
|
NCBI chr18:74,496,363...74,523,454
Ensembl chr18:74,495,816...74,523,454
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|
G |
CNN3 |
calponin 3 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of CNN3 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 1:94,896,957...94,927,110
Ensembl chr 1:94,896,949...94,927,223
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|
G |
CNTFR |
ciliary neurotrophic factor receptor |
increases expression |
ISO |
Thapsigargin results in increased expression of CNTFR protein |
CTD |
PMID:35544339 |
|
NCBI chr 9:34,551,433...34,590,852
Ensembl chr 9:34,551,432...34,590,140
|
|
G |
CNTNAP2 |
contactin associated protein 2 |
increases expression |
EXP |
Thapsigargin results in increased expression of CNTNAP2 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 7:146,116,801...148,420,998
Ensembl chr 7:146,116,002...148,420,998
|
|
G |
COG1 |
component of oligomeric golgi complex 1 |
increases expression |
EXP |
Thapsigargin results in increased expression of COG1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr17:73,193,055...73,208,507
Ensembl chr17:73,193,055...73,208,507
|
|
G |
COG3 |
component of oligomeric golgi complex 3 |
increases expression |
EXP |
Thapsigargin results in increased expression of COG3 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr13:45,464,939...45,536,701
Ensembl chr13:45,464,898...45,536,701
|
|
G |
COG6 |
component of oligomeric golgi complex 6 |
increases expression |
EXP |
Thapsigargin results in increased expression of COG6 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr13:39,655,627...39,791,666
Ensembl chr13:39,655,627...39,791,666
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|
G |
COL11A1 |
collagen type XI alpha 1 chain |
increases expression |
ISO |
Thapsigargin results in increased expression of COL11A1 protein |
CTD |
PMID:24648495 |
|
NCBI chr 1:102,876,473...103,108,522
Ensembl chr 1:102,876,467...103,108,872
|
|
G |
COL5A1 |
collagen type V alpha 1 chain |
increases expression decreases expression |
EXP |
Thapsigargin results in increased expression of COL5A1 mRNA Thapsigargin results in decreased expression of COL5A1 mRNA |
CTD |
PMID:22378314 PMID:29453283 |
|
NCBI chr 9:134,641,803...134,844,843
Ensembl chr 9:134,641,803...134,844,843
|
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G |
COL5A2 |
collagen type V alpha 2 chain |
increases expression |
ISO |
Thapsigargin results in increased expression of COL5A2 protein |
CTD |
PMID:24648495 |
|
NCBI chr 2:189,031,898...189,441,111
Ensembl chr 2:189,031,898...189,225,312
|
|
G |
COL6A3 |
collagen type VI alpha 3 chain |
multiple interactions |
EXP |
Thapsigargin promotes the reaction [COL6A3 gene mutant form results in increased susceptibility to Rotenone] |
CTD |
PMID:18435905 |
|
NCBI chr 2:237,324,018...237,414,164
Ensembl chr 2:237,324,003...237,414,328
|
|
G |
COLEC12 |
collectin subfamily member 12 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of COLEC12 protein |
CTD |
PMID:24648495 |
|
NCBI chr18:316,737...500,701
Ensembl chr18:316,737...500,722
|
|
G |
COPA |
COPI coat complex subunit alpha |
increases expression |
EXP |
Thapsigargin results in increased expression of COPA mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 1:160,288,594...160,343,250
Ensembl chr 1:160,288,594...160,343,566
|
|
G |
COPB2 |
COPI coat complex subunit beta 2 |
increases expression |
ISO |
Thapsigargin results in increased expression of COPB2 protein |
CTD |
PMID:35544339 |
|
NCBI chr 3:139,357,406...139,389,680
Ensembl chr 3:139,353,946...139,389,736
|
|
G |
COPG1 |
COPI coat complex subunit gamma 1 |
increases expression |
EXP ISO |
Thapsigargin results in increased expression of COPG1 mRNA Thapsigargin results in increased expression of COPG1 protein |
CTD |
PMID:22378314 PMID:29453283 PMID:35544339 |
|
NCBI chr 3:129,249,606...129,277,773
Ensembl chr 3:129,249,606...129,277,773
|
|
G |
COPS4 |
COP9 signalosome subunit 4 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of COPS4 protein |
CTD |
PMID:21692457 |
|
NCBI chr 4:83,035,183...83,075,818
Ensembl chr 4:83,034,447...83,075,818
|
|
G |
COPS7A |
COP9 signalosome subunit 7A |
decreases expression |
ISO |
Thapsigargin results in decreased expression of COPS7A protein |
CTD |
PMID:24648495 |
|
NCBI chr12:6,724,046...6,731,865
Ensembl chr12:6,724,014...6,731,875
|
|
G |
COQ3 |
coenzyme Q3, methyltransferase |
decreases expression |
EXP |
Thapsigargin results in decreased expression of COQ3 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 6:99,369,401...99,394,195
Ensembl chr 6:99,369,401...99,394,195
|
|
G |
COQ8A |
coenzyme Q8A |
increases expression |
EXP |
Thapsigargin results in increased expression of COQ8A mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 1:226,940,294...226,987,544
Ensembl chr 1:226,940,286...226,987,544
|
|
G |
CORO1A |
coronin 1A |
decreases expression |
EXP |
Thapsigargin results in decreased expression of CORO1A mRNA |
CTD |
PMID:22378314 |
|
NCBI chr16:30,183,602...30,189,076
Ensembl chr16:30,182,827...30,189,076
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G |
CORO1B |
coronin 1B |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CORO1B protein |
CTD |
PMID:35544339 |
|
NCBI chr11:67,435,510...67,443,809
Ensembl chr11:67,435,510...67,443,821
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G |
COTL1 |
coactosin like F-actin binding protein 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of COTL1 protein |
CTD |
PMID:24648495 |
|
NCBI chr16:84,565,596...84,618,078
Ensembl chr16:84,565,596...84,618,078
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G |
COX10 |
cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10 |
increases expression |
EXP |
Thapsigargin results in increased expression of COX10 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr17:14,069,504...14,208,677
Ensembl chr17:14,069,490...14,231,736
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G |
COX11 |
cytochrome c oxidase copper chaperone COX11 |
increases expression |
EXP |
Thapsigargin results in increased expression of COX11 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr17:54,951,902...54,968,785
Ensembl chr17:54,951,902...54,968,703
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G |
COX17 |
cytochrome c oxidase copper chaperone COX17 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of COX17 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 3:119,663,975...119,677,406
Ensembl chr 3:119,654,513...119,677,454
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G |
COX4I1 |
cytochrome c oxidase subunit 4I1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of COX4I1 protein |
CTD |
PMID:35544339 |
|
NCBI chr16:85,799,695...85,807,068
Ensembl chr16:85,798,633...85,807,068
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G |
COX5B |
cytochrome c oxidase subunit 5B |
decreases expression |
ISO |
Thapsigargin results in decreased expression of COX5B protein |
CTD |
PMID:35544339 |
|
NCBI chr 2:97,646,062...97,648,383
Ensembl chr 2:97,646,062...97,648,383
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G |
COX6B1 |
cytochrome c oxidase subunit 6B1 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of COX6B1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr19:35,648,323...35,658,782
Ensembl chr19:35,648,323...35,658,782
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G |
COX6C |
cytochrome c oxidase subunit 6C |
decreases expression |
EXP ISO |
Thapsigargin results in decreased expression of COX6C mRNA Thapsigargin results in decreased expression of COX6C protein |
CTD |
PMID:22378314 PMID:35544339 |
|
NCBI chr 8:99,877,865...99,893,707
Ensembl chr 8:99,873,200...99,893,707
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G |
COX7B |
cytochrome c oxidase subunit 7B |
decreases expression |
EXP |
Thapsigargin results in decreased expression of COX7B mRNA |
CTD |
PMID:22378314 |
|
NCBI chr X:77,899,468...77,907,376
Ensembl chr X:77,899,440...77,907,376
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G |
CPNE1 |
copine 1 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of CPNE1 protein |
CTD |
PMID:21692457 |
|
NCBI chr20:35,626,044...35,664,900
Ensembl chr20:35,626,031...35,664,956
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G |
CPOX |
coproporphyrinogen oxidase |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CPOX protein |
CTD |
PMID:35544339 |
|
NCBI chr 3:98,570,488...98,593,611
Ensembl chr 3:98,579,446...98,593,648
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G |
CPSF1 |
cleavage and polyadenylation specific factor 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of CPSF1 protein |
CTD |
PMID:24648495 |
|
NCBI chr 8:144,393,231...144,409,335
Ensembl chr 8:144,393,229...144,409,335
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G |
CPSF7 |
cleavage and polyadenylation specific factor 7 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CPSF7 protein |
CTD |
PMID:35544339 |
|
NCBI chr11:61,402,729...61,429,975
Ensembl chr11:61,402,641...61,430,031
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G |
CPT1C |
carnitine palmitoyltransferase 1C |
increases expression |
EXP |
Thapsigargin results in increased expression of CPT1C mRNA |
CTD |
PMID:22378314 |
|
NCBI chr19:49,690,662...49,713,731
Ensembl chr19:49,690,898...49,713,731
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G |
CR1L |
complement C3b/C4b receptor 1 like |
increases expression |
ISO |
Thapsigargin results in increased expression of CR1L protein |
CTD |
PMID:35544339 |
|
NCBI chr 1:207,645,133...207,723,703
Ensembl chr 1:207,645,113...207,738,416
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G |
CRABP1 |
cellular retinoic acid binding protein 1 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of CRABP1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr15:78,340,353...78,348,225
Ensembl chr15:78,340,353...78,348,225
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G |
CRABP2 |
cellular retinoic acid binding protein 2 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of CRABP2 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 1:156,699,606...156,705,784
Ensembl chr 1:156,699,606...156,705,816
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G |
CRAT |
carnitine O-acetyltransferase |
increases expression |
EXP |
Thapsigargin results in increased expression of CRAT mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 9:129,094,794...129,110,793
Ensembl chr 9:129,094,142...129,111,189
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G |
CREB1 |
cAMP responsive element binding protein 1 |
multiple interactions affects localization |
ISO |
Cycloheximide inhibits the reaction [Thapsigargin affects the localization of CREB1 mRNA]; Emetine inhibits the reaction [Thapsigargin affects the localization of CREB1 mRNA] |
CTD |
PMID:29576526 |
|
NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988
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G |
CREB3L1 |
cAMP responsive element binding protein 3 like 1 |
increases activity multiple interactions |
EXP |
Thapsigargin results in increased activity of CREB3L1 protein [Thapsigargin results in increased activity of CREB3L1 protein] which results in increased expression of VEGFA mRNA |
CTD |
PMID:23383089 |
|
NCBI chr11:46,277,662...46,321,409
Ensembl chr11:46,277,662...46,321,409
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|
G |
CREB3L2 |
cAMP responsive element binding protein 3 like 2 |
increases expression |
EXP |
Thapsigargin results in increased expression of CREB3L2 mRNA |
CTD |
PMID:22378314 PMID:29453283 |
|
NCBI chr 7:137,874,979...138,002,086
Ensembl chr 7:137,874,979...138,002,086
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G |
CREBBP |
CREB binding protein |
increases expression |
EXP |
Thapsigargin results in increased expression of CREBBP mRNA |
CTD |
PMID:24247028 |
|
NCBI chr16:3,725,054...3,880,713
Ensembl chr16:3,725,054...3,880,713
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G |
CREG1 |
cellular repressor of E1A stimulated genes 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CREG1 protein |
CTD |
PMID:24648495 |
|
NCBI chr 1:167,541,013...167,553,762
Ensembl chr 1:167,529,117...167,553,805
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|
G |
CRELD1 |
cysteine rich with EGF like domains 1 |
increases expression |
EXP |
Thapsigargin results in increased expression of CRELD1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 3:9,933,834...9,945,406
Ensembl chr 3:9,933,793...9,945,413
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G |
CRELD2 |
cysteine rich with EGF like domains 2 |
increases expression decreases expression |
EXP ISO |
Thapsigargin results in increased expression of CRELD2 mRNA; Thapsigargin results in increased expression of CRELD2 protein Thapsigargin results in decreased expression of CRELD2 protein |
CTD |
PMID:22378314 PMID:24648495 PMID:29453283 PMID:35544339 |
|
NCBI chr22:49,918,634...49,927,537
Ensembl chr22:49,918,167...49,927,540
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G |
CRK |
CRK proto-oncogene, adaptor protein |
multiple interactions |
ISO |
Thapsigargin inhibits the reaction [Sincalide results in increased phosphorylation of CRK protein] |
CTD |
PMID:16187300 |
|
NCBI chr17:1,420,693...1,456,232
Ensembl chr17:1,420,689...1,463,162
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G |
CRMP1 |
collapsin response mediator protein 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of CRMP1 protein |
CTD |
PMID:35544339 |
|
NCBI chr 4:5,820,764...5,893,086
Ensembl chr 4:5,748,084...5,893,086
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G |
CRNKL1 |
crooked neck pre-mRNA splicing factor 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CRNKL1 protein |
CTD |
PMID:35544339 |
|
NCBI chr20:20,034,368...20,056,046
Ensembl chr20:20,034,368...20,056,046
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G |
CRTAC1 |
cartilage acidic protein 1 |
increases expression |
EXP |
Thapsigargin results in increased expression of CRTAC1 mRNA |
CTD |
PMID:29453283 |
|
NCBI chr10:97,865,000...98,030,621
Ensembl chr10:97,865,000...98,030,828
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G |
CRY1 |
cryptochrome circadian regulator 1 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of CRY1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr12:106,991,364...107,093,549
Ensembl chr12:106,991,364...107,093,549
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|
G |
CRYBB2 |
crystallin beta B2 |
increases expression |
EXP |
Thapsigargin results in increased expression of CRYBB2 mRNA |
CTD |
PMID:29453283 |
|
NCBI chr22:25,211,661...25,231,869
Ensembl chr22:25,212,564...25,231,870
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G |
CRYBG3 |
crystallin beta-gamma domain containing 3 |
increases expression |
ISO |
Thapsigargin results in increased expression of CRYBG3 protein |
CTD |
PMID:24648495 |
|
NCBI chr 3:97,822,011...97,944,984
Ensembl chr 3:97,822,011...97,944,984
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G |
CRYZ |
crystallin zeta |
multiple interactions decreases expression increases expression |
EXP |
Drugs, Chinese Herbal promotes the reaction [Thapsigargin results in increased expression of CRYZ mRNA] Thapsigargin results in decreased expression of CRYZ mRNA |
CTD |
PMID:19442820 PMID:22378314 |
|
NCBI chr 1:74,705,486...74,733,050
Ensembl chr 1:74,705,482...74,733,408
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G |
CS |
citrate synthase |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CS mRNA |
CTD |
PMID:28223344 |
|
NCBI chr12:56,271,699...56,300,330
Ensembl chr12:56,271,699...56,300,391
|
|
G |
CSNK2A2 |
casein kinase 2 alpha 2 |
increases expression |
EXP |
Thapsigargin results in increased expression of CSNK2A2 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr16:58,157,907...58,198,106
Ensembl chr16:58,157,907...58,198,106
|
|
G |
CSPG5 |
chondroitin sulfate proteoglycan 5 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of CSPG5 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 3:47,562,238...47,580,240
Ensembl chr 3:47,562,238...47,580,792
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G |
CSRNP1 |
cysteine and serine rich nuclear protein 1 |
increases expression |
EXP |
Thapsigargin results in increased expression of CSRNP1 mRNA |
CTD |
PMID:29453283 |
|
NCBI chr 3:39,141,855...39,154,641
Ensembl chr 3:39,141,855...39,154,562
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|
G |
CSRP2 |
cysteine and glycine rich protein 2 |
decreases expression |
EXP ISO |
Thapsigargin results in decreased expression of CSRP2 mRNA Thapsigargin results in decreased expression of CSRP2 protein |
CTD |
PMID:22378314 PMID:35544339 |
|
NCBI chr12:76,858,709...76,879,019
Ensembl chr12:76,858,709...76,879,023
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G |
CSTB |
cystatin B |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CSTB protein |
CTD |
PMID:35544339 |
|
NCBI chr21:43,773,950...43,776,308
Ensembl chr21:43,772,511...43,776,330
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G |
CSTF2 |
cleavage stimulation factor subunit 2 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of CSTF2 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr X:100,820,391...100,841,520
Ensembl chr X:100,820,391...100,841,520
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G |
CTBP1 |
C-terminal binding protein 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CTBP1 protein |
CTD |
PMID:35544339 |
|
NCBI chr 4:1,211,445...1,250,355
Ensembl chr 4:1,211,445...1,250,333
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G |
CTBS |
chitobiase |
increases expression |
ISO |
Thapsigargin results in increased expression of CTBS protein |
CTD |
PMID:35544339 |
|
NCBI chr 1:84,549,611...84,574,440
Ensembl chr 1:84,549,611...84,574,480
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G |
CTF1 |
cardiotrophin 1 |
multiple interactions |
EXP |
[Thapsigargin co-treated with 4-methoxycinnamate methyl ester] results in decreased expression of CTF1 mRNA; caffeic acid promotes the reaction [Thapsigargin results in decreased expression of CTF1 mRNA]; Drugs, Chinese Herbal promotes the reaction [Thapsigargin results in decreased expression of CTF1 mRNA] |
CTD |
PMID:19442820 |
|
NCBI chr16:30,895,846...30,903,560
Ensembl chr16:30,896,614...30,903,547
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G |
CTH |
cystathionine gamma-lyase |
increases expression |
EXP |
Thapsigargin results in increased expression of CTH mRNA; Thapsigargin results in increased expression of CTH protein |
CTD |
PMID:29453283 |
|
NCBI chr 1:70,411,268...70,439,851
Ensembl chr 1:70,411,218...70,439,851
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G |
CTNNBL1 |
catenin beta like 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CTNNBL1 protein |
CTD |
PMID:35544339 |
|
NCBI chr20:37,694,030...37,872,118
Ensembl chr20:37,694,030...37,872,129
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G |
CTPS1 |
CTP synthase 1 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of CTPS1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 1:40,979,696...41,012,565
Ensembl chr 1:40,979,300...41,012,565
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G |
CTPS2 |
CTP synthase 2 |
increases expression |
ISO |
Thapsigargin results in increased expression of CTPS2 protein |
CTD |
PMID:35544339 |
|
NCBI chr X:16,587,999...16,712,910
Ensembl chr X:16,587,999...16,712,936
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G |
CTR9 |
CTR9 homolog, Paf1/RNA polymerase II complex component |
increases expression |
ISO |
Thapsigargin results in increased expression of CTR9 protein |
CTD |
PMID:24648495 |
|
NCBI chr11:10,751,246...10,779,746
Ensembl chr11:10,751,018...10,801,625
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G |
CTSB |
cathepsin B |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CTSB protein |
CTD |
PMID:35544339 |
|
NCBI chr 8:11,842,524...11,868,087
Ensembl chr 8:11,842,524...11,869,533
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G |
CTSL |
cathepsin L |
multiple interactions |
EXP |
Thapsigargin inhibits the reaction [Cadmium Chloride results in increased cleavage of CTSL protein] |
CTD |
PMID:25639782 |
|
NCBI chr 9:87,726,119...87,731,469
Ensembl chr 9:87,724,051...87,731,469
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G |
CTTN |
cortactin |
increases expression |
ISO |
Thapsigargin results in increased expression of CTTN protein |
CTD |
PMID:35544339 |
|
NCBI chr11:70,398,529...70,436,575
Ensembl chr11:70,398,404...70,436,584
|
|
G |
CTXN1 |
cortexin 1 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of CTXN1 mRNA |
CTD |
PMID:29453283 |
|
NCBI chr19:7,924,491...7,926,135
Ensembl chr19:7,924,491...7,926,135
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G |
CWC15 |
CWC15 spliceosome associated protein homolog |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CWC15 protein |
CTD |
PMID:35544339 |
|
NCBI chr11:94,962,620...94,973,556
Ensembl chr11:94,962,620...94,973,586
|
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G |
CXCL1 |
C-X-C motif chemokine ligand 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of CXCL1 mRNA |
CTD |
PMID:8764118 |
|
NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308
|
|
G |
CXCL2 |
C-X-C motif chemokine ligand 2 |
multiple interactions |
EXP |
4-methoxycinnamate methyl ester promotes the reaction [Thapsigargin results in decreased expression of CXCL2 mRNA]; caffeic acid promotes the reaction [Thapsigargin results in decreased expression of CXCL2 mRNA]; Drugs, Chinese Herbal promotes the reaction [Thapsigargin results in decreased expression of CXCL2 mRNA] |
CTD |
PMID:19442820 |
|
NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196
|
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G |
CXCL8 |
C-X-C motif chemokine ligand 8 |
increases expression |
EXP |
Thapsigargin results in increased expression of CXCL8 mRNA |
CTD |
PMID:18951912 PMID:29453283 |
|
NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716
|
|
G |
CYB561D2 |
cytochrome b561 family member D2 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CYB561D2 protein |
CTD |
PMID:24648495 |
|
NCBI chr 3:50,350,862...50,354,069
Ensembl chr 3:50,350,845...50,358,460
|
|
G |
CYB5A |
cytochrome b5 type A |
decreases expression |
EXP |
Thapsigargin results in decreased expression of CYB5A mRNA |
CTD |
PMID:22378314 |
|
NCBI chr18:74,250,846...74,291,963
Ensembl chr18:74,250,846...74,291,973
|
|
G |
CYB5B |
cytochrome b5 type B |
decreases expression increases expression |
EXP ISO |
Thapsigargin results in decreased expression of CYB5B mRNA Thapsigargin results in increased expression of CYB5B protein |
CTD |
PMID:22378314 PMID:35544339 |
|
NCBI chr16:69,424,619...69,466,264
Ensembl chr16:69,398,402...69,466,264
|
|
G |
CYB5R1 |
cytochrome b5 reductase 1 |
increases expression decreases expression |
EXP ISO |
Thapsigargin results in increased expression of CYB5R1 mRNA Thapsigargin results in decreased expression of CYB5R1 protein |
CTD |
PMID:29453283 PMID:35544339 |
|
NCBI chr 1:202,961,873...202,967,257
Ensembl chr 1:202,961,873...202,967,275
|
|
G |
CYBA |
cytochrome b-245 alpha chain |
decreases expression |
EXP |
Thapsigargin results in decreased expression of CYBA mRNA |
CTD |
PMID:29453283 |
|
NCBI chr16:88,643,289...88,651,053
Ensembl chr16:88,643,275...88,651,083
|
|
G |
CYCS |
cytochrome c, somatic |
decreases expression |
EXP |
Thapsigargin results in decreased expression of CYCS mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260
|
|
G |
CYFIP1 |
cytoplasmic FMR1 interacting protein 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of CYFIP1 protein |
CTD |
PMID:24648495 |
|
NCBI chr15:22,867,052...22,980,898
Ensembl chr15:22,867,052...22,981,063
|
|
G |
CYGB |
cytoglobin |
decreases expression |
EXP |
Thapsigargin results in decreased expression of CYGB mRNA |
CTD |
PMID:22378314 |
|
NCBI chr17:76,527,356...76,551,193
Ensembl chr17:76,527,356...76,551,175
|
|
G |
CYP1B1 |
cytochrome P450 family 1 subfamily B member 1 |
increases expression |
EXP |
Thapsigargin results in increased expression of CYP1B1 mRNA |
CTD |
PMID:29453283 |
|
NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902
|
|
G |
CYP2A6 |
cytochrome P450 family 2 subfamily A member 6 |
increases expression |
ISO |
Thapsigargin results in increased expression of CYP2A5 mRNA |
CTD |
PMID:35341795 |
|
NCBI chr19:40,843,541...40,850,447
Ensembl chr19:40,843,541...40,850,447
|
|
G |
CYP3A4 |
cytochrome P450 family 3 subfamily A member 4 |
multiple interactions |
EXP |
NR1I2 protein inhibits the reaction [Thapsigargin inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]]; Thapsigargin inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA] |
CTD |
PMID:25616597 |
|
NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248
|
|
G |
CYP4F3 |
cytochrome P450 family 4 subfamily F member 3 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of CYP4F3 mRNA |
CTD |
PMID:19442820 |
|
NCBI chr19:15,640,897...15,662,825
Ensembl chr19:15,640,897...15,662,825
|
|
G |
CYP4V2 |
cytochrome P450 family 4 subfamily V member 2 |
increases expression |
EXP |
Thapsigargin results in increased expression of CYP4V2 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 4:186,191,567...186,213,463
Ensembl chr 4:186,191,567...186,213,463
|
|
G |
CYP4X1 |
cytochrome P450 family 4 subfamily X member 1 |
increases expression |
EXP |
Thapsigargin results in increased expression of CYP4X1 mRNA |
CTD |
PMID:29453283 |
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NCBI chr 1:46,961,364...47,055,432
Ensembl chr 1:47,023,669...47,050,751
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CYP51A1 |
cytochrome P450 family 51 subfamily A member 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of CYP51 protein |
CTD |
PMID:35544339 |
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NCBI chr 7:92,112,153...92,134,803
Ensembl chr 7:92,084,987...92,134,803
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G |
CZIB |
CXXC motif containing zinc binding protein |
decreases expression |
ISO |
Thapsigargin results in decreased expression of CZIB protein |
CTD |
PMID:35544339 |
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NCBI chr 1:53,214,099...53,220,634
Ensembl chr 1:53,214,099...53,220,634
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G |
DAP |
death associated protein |
multiple interactions increases expression |
EXP |
4-methoxycinnamate methyl ester promotes the reaction [Thapsigargin results in decreased expression of DAP mRNA]; caffeic acid promotes the reaction [Thapsigargin results in decreased expression of DAP mRNA]; Drugs, Chinese Herbal promotes the reaction [Thapsigargin results in decreased expression of DAP mRNA] Thapsigargin results in increased expression of DAP mRNA |
CTD |
PMID:19442820 PMID:22378314 |
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NCBI chr 5:10,679,230...10,761,234
Ensembl chr 5:10,679,230...10,761,234
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G |
DBI |
diazepam binding inhibitor, acyl-CoA binding protein |
decreases expression |
EXP |
Thapsigargin results in decreased expression of DBI mRNA |
CTD |
PMID:22378314 |
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NCBI chr 2:119,366,977...119,372,543
Ensembl chr 2:119,366,924...119,372,550
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G |
DBNL |
drebrin like |
decreases expression |
EXP |
Thapsigargin results in decreased expression of DBNL mRNA |
CTD |
PMID:22378314 |
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NCBI chr 7:44,044,702...44,069,456
Ensembl chr 7:44,044,640...44,069,456
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G |
DCK |
deoxycytidine kinase |
decreases expression |
ISO |
Thapsigargin results in decreased expression of DCK protein |
CTD |
PMID:35544339 |
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NCBI chr 4:70,993,649...71,030,914
Ensembl chr 4:70,992,538...71,030,914
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G |
DCTPP1 |
dCTP pyrophosphatase 1 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of DCTPP1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr16:30,423,615...30,430,030
Ensembl chr16:30,423,615...30,430,030
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G |
DCX |
doublecortin |
decreases expression |
ISO |
Thapsigargin results in decreased expression of DCX protein |
CTD |
PMID:35544339 |
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NCBI chr X:111,293,779...111,412,192
Ensembl chr X:111,293,779...111,412,429
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G |
DDAH1 |
dimethylarginine dimethylaminohydrolase 1 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of DDAH1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 1:85,318,485...85,578,200
Ensembl chr 1:85,318,481...85,578,363
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G |
DDB1 |
damage specific DNA binding protein 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of DDB1 protein |
CTD |
PMID:24648495 |
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NCBI chr11:61,299,451...61,333,105
Ensembl chr11:61,299,451...61,342,596
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G |
DDC |
dopa decarboxylase |
decreases expression |
EXP |
Thapsigargin results in decreased expression of DDC mRNA |
CTD |
PMID:22378314 |
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NCBI chr 7:50,458,442...50,565,405
Ensembl chr 7:50,458,436...50,565,405
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G |
DDIAS |
DNA damage induced apoptosis suppressor |
decreases expression |
EXP |
Thapsigargin results in decreased expression of DDIAS mRNA |
CTD |
PMID:22378314 |
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NCBI chr11:82,901,736...82,934,659
Ensembl chr11:82,899,975...82,958,277
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G |
DDIT3 |
DNA damage inducible transcript 3 |
multiple interactions increases expression increases activity decreases response to substance |
EXP ISO |
ATF6 promotes the reaction [Thapsigargin results in increased expression of DDIT3 protein]; demethoxycurcumin analog inhibits the reaction [Thapsigargin results in increased expression of DDIT3 protein]; Doxorubicin inhibits the reaction [Thapsigargin results in increased expression of DDIT3 protein]; EIF2AK3 promotes the reaction [Thapsigargin results in increased expression of DDIT3 protein]; Luteolin inhibits the reaction [Thapsigargin results in increased expression of DDIT3 mRNA]; Luteolin inhibits the reaction [Thapsigargin results in increased expression of DDIT3 protein]; Quercetin inhibits the reaction [Thapsigargin results in increased expression of DDIT3 mRNA]; Thapsigargin promotes the reaction [DDIT3 protein binds to LCN2 promoter]; Thapsigargin promotes the reaction [pterostilbene results in increased expression of DDIT3 protein]; Thapsigargin results in increased expression of and affects the localization of DDIT3 protein thapsigargin promotes the reaction [glucose increases expression of Ddit3 protein in cardiac muscle cell] Thapsigargin results in increased expression of DDIT3 mRNA; Thapsigargin results in increased expression of DDIT3 protein 1-Deoxynojirimycin inhibits the reaction [Thapsigargin results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [Thapsigargin results in increased expression of DDIT3 protein]; GW 506033X inhibits the reaction [Thapsigargin results in increased expression of DDIT3 mRNA]; salubrinal promotes the reaction [Thapsigargin results in increased expression of DDIT3 protein]; Thapsigargin results in increased expression of and affects the localization of DDIT3 protein Thapsigargin results in increased activity of DDIT3 protein 2-aminoethoxydiphenyl borate inhibits the reaction [Thapsigargin results in increased expression of DDIT3 mRNA]; 7-methyl-5-(1-((3-(trifluoromethyl)phenyl)acetyl)-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo(2,3-d)pyrimidin-4-amine inhibits the reaction [Thapsigargin results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Thapsigargin results in increased expression of DDIT3 protein]; Apigenin inhibits the reaction [Thapsigargin results in increased expression of DDIT3 protein]; EIF2S1 protein modified form affects the reaction [Thapsigargin results in increased expression of DDIT3 mRNA]; EIF2S1 protein modified form affects the reaction [Thapsigargin results in increased expression of DDIT3 protein]; Glutathione inhibits the reaction [Thapsigargin results in increased expression of DDIT3 protein]; Luteolin inhibits the reaction [Thapsigargin results in increased expression of DDIT3 protein]; PTPN1 gene mutant form promotes the reaction [Thapsigargin results in increased expression of DDIT3 mRNA]; PTPN1 gene mutant form promotes the reaction [Thapsigargin results in increased expression of DDIT3 protein]; salubrinal inhibits the reaction [Thapsigargin results in increased expression of DDIT3 protein]; Thapsigargin inhibits the reaction [7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid inhibits the reaction [Palmitic Acid results in increased expression of DDIT3 protein]]; Thapsigargin promotes the reaction [Arsenic Trioxide results in increased expression of DDIT3 protein]; Vaticanol B inhibits the reaction [Thapsigargin results in increased expression of DDIT3 protein] DDIT3 results in decreased susceptibility to Thapsigargin |
CTD RGD |
PMID:16298333 PMID:16330322 PMID:16338971 PMID:17283163 PMID:17332266 PMID:17353921 PMID:17475668 PMID:19028522 PMID:19135031 PMID:19139269 PMID:19285962 PMID:19428936 PMID:20022965 PMID:20493918 PMID:20589738 PMID:20626587 PMID:21525004 PMID:21694771 PMID:22378314 PMID:22509299 PMID:22641616 PMID:22800509 PMID:22843330 PMID:22935518 PMID:23123503 PMID:24648495 PMID:24668805 PMID:24865413 PMID:25289770 PMID:25324550 PMID:25341683 PMID:26264395 PMID:26513129 PMID:27226639 PMID:27358234 PMID:27587023 PMID:27638049 PMID:28223344 PMID:28315715 PMID:28844859 PMID:28940366 PMID:28942281 PMID:29109149 PMID:29414781 PMID:29453283 PMID:30508555 PMID:32407927 PMID:32535746 PMID:32574669 PMID:32578922 PMID:34915026 PMID:35033536 PMID:35544339 PMID:36044268 More...
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RGD:156430337 |
NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737
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G |
DDOST |
dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit |
increases expression |
EXP ISO |
Thapsigargin results in increased expression of DDOST mRNA Thapsigargin results in increased expression of DDOST protein |
CTD |
PMID:22378314 PMID:35544339 |
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NCBI chr 1:20,651,777...20,661,369
Ensembl chr 1:20,651,767...20,661,544
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G |
DDR2 |
discoidin domain receptor tyrosine kinase 2 |
increases expression |
ISO |
Thapsigargin results in increased expression of DDR2 protein |
CTD |
PMID:24648495 |
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NCBI chr 1:162,630,863...162,787,405
Ensembl chr 1:162,631,373...162,787,405
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G |
DDRGK1 |
DDRGK domain containing 1 |
increases expression |
EXP |
Thapsigargin results in increased expression of DDRGK1 mRNA |
CTD |
PMID:29453283 |
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NCBI chr20:3,190,350...3,204,682
Ensembl chr20:3,190,350...3,204,685
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G |
DDX21 |
DExD-box helicase 21 |
increases expression |
ISO |
Thapsigargin results in increased expression of DDX21 protein |
CTD |
PMID:35544339 |
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NCBI chr10:68,956,170...68,985,068
Ensembl chr10:68,956,135...68,985,068
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G |
DECR1 |
2,4-dienoyl-CoA reductase 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of DECR1 protein |
CTD |
PMID:35544339 |
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NCBI chr 8:90,001,477...90,053,633
Ensembl chr 8:90,001,405...90,053,633
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G |
DEK |
DEK proto-oncogene |
decreases expression |
ISO |
Thapsigargin results in decreased expression of DEK protein |
CTD |
PMID:35544339 |
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NCBI chr 6:18,223,860...18,264,530
Ensembl chr 6:18,223,860...18,264,548
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G |
DENND4C |
DENN domain containing 4C |
increases expression |
ISO |
Thapsigargin results in increased expression of DENND4C protein |
CTD |
PMID:24648495 |
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NCBI chr 9:19,230,513...19,374,281
Ensembl chr 9:19,230,435...19,374,281
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G |
DEPDC1B |
DEP domain containing 1B |
decreases expression |
EXP |
Thapsigargin results in decreased expression of DEPDC1B mRNA |
CTD |
PMID:22378314 |
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NCBI chr 5:60,596,912...60,700,166
Ensembl chr 5:60,596,912...60,700,190
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G |
DEPTOR |
DEP domain containing MTOR interacting protein |
increases expression |
EXP |
Thapsigargin results in increased expression of DEPTOR mRNA |
CTD |
PMID:22378314 |
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NCBI chr 8:119,873,722...120,050,918
Ensembl chr 8:119,873,717...120,050,918
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G |
DERL2 |
derlin 2 |
increases expression |
EXP |
Thapsigargin results in increased expression of DERL2 mRNA |
CTD |
PMID:22378314 |
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NCBI chr17:5,471,254...5,486,817
Ensembl chr17:5,471,254...5,486,811
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G |
DGLUCY |
D-glutamate cyclase |
decreases expression |
EXP |
Thapsigargin results in decreased expression of DGLUCY mRNA |
CTD |
PMID:22378314 |
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NCBI chr14:91,060,333...91,225,632
Ensembl chr14:91,060,333...91,225,632
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G |
DHCR24 |
24-dehydrocholesterol reductase |
decreases expression increases expression |
EXP ISO |
Thapsigargin results in decreased expression of DHCR24 mRNA Thapsigargin results in increased expression of DHCR24 protein |
CTD |
PMID:22378314 PMID:35544339 |
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NCBI chr 1:54,849,627...54,887,195
Ensembl chr 1:54,849,627...54,887,195
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G |
DHCR7 |
7-dehydrocholesterol reductase |
decreases expression increases expression |
EXP ISO |
Thapsigargin results in decreased expression of DHCR7 mRNA Thapsigargin results in increased expression of DHCR7 protein |
CTD |
PMID:22378314 PMID:35544339 |
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NCBI chr11:71,427,287...71,449,043
Ensembl chr11:71,428,193...71,452,868
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G |
DHRS13 |
dehydrogenase/reductase 13 |
increases expression |
EXP |
Thapsigargin results in increased expression of DHRS13 mRNA |
CTD |
PMID:29453283 |
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NCBI chr17:28,897,781...28,903,079
Ensembl chr17:28,897,781...28,903,079
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G |
DHRS3 |
dehydrogenase/reductase 3 |
increases expression |
EXP |
Thapsigargin results in increased expression of DHRS3 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 1:12,567,910...12,618,210
Ensembl chr 1:12,567,909...12,620,133
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G |
DHX36 |
DEAH-box helicase 36 |
increases expression |
ISO |
Thapsigargin results in increased expression of DHX36 protein |
CTD |
PMID:24648495 PMID:35544339 |
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NCBI chr 3:154,272,546...154,324,487
Ensembl chr 3:154,272,546...154,324,487
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G |
DHX9 |
DExH-box helicase 9 |
increases expression |
ISO |
Thapsigargin results in increased expression of DHX9 protein |
CTD |
PMID:24648495 |
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NCBI chr 1:182,839,347...182,887,982
Ensembl chr 1:182,839,347...182,887,982
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G |
DIABLO |
diablo IAP-binding mitochondrial protein |
affects response to substance increases expression affects localization |
EXP |
DIABLO protein affects the susceptibility to Thapsigargin Thapsigargin results in increased expression of DIABLO mRNA Thapsigargin affects the localization of DIABLO protein |
CTD |
PMID:15339911 PMID:16382148 PMID:22378314 |
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NCBI chr12:122,207,662...122,227,456
Ensembl chr12:122,207,668...122,226,062
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G |
DIAPH2 |
diaphanous related formin 2 |
increases expression |
ISO |
Thapsigargin results in increased expression of DIAP2 protein |
CTD |
PMID:24648495 |
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NCBI chr X:96,684,842...97,604,997
Ensembl chr X:96,684,712...97,604,997
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G |
DIAPH3 |
diaphanous related formin 3 |
increases expression |
ISO |
Thapsigargin results in increased expression of DIAPH3 protein |
CTD |
PMID:24648495 |
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NCBI chr13:59,665,583...60,163,928
Ensembl chr13:59,665,583...60,163,928
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G |
DKK1 |
dickkopf WNT signaling pathway inhibitor 1 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of DKK1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr10:52,314,281...52,317,657
Ensembl chr10:52,314,281...52,318,042
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G |
DLD |
dihydrolipoamide dehydrogenase |
decreases expression |
EXP |
Thapsigargin results in decreased expression of DLD mRNA |
CTD |
PMID:22378314 |
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NCBI chr 7:107,891,107...107,921,198
Ensembl chr 7:107,891,162...107,931,730
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G |
DLG4 |
discs large MAGUK scaffold protein 4 |
increases expression |
EXP |
Thapsigargin results in increased expression of DLG4 mRNA |
CTD |
PMID:22378314 |
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NCBI chr17:7,187,187...7,220,050
Ensembl chr17:7,187,187...7,219,836
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G |
DLGAP5 |
DLG associated protein 5 |
decreases expression increases expression |
EXP ISO |
Thapsigargin results in decreased expression of DLGAP5 mRNA Thapsigargin results in increased expression of DLGAP5 protein |
CTD |
PMID:22378314 PMID:24648495 |
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NCBI chr14:55,148,135...55,191,585
Ensembl chr14:55,148,112...55,191,608
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G |
DLK1 |
delta like non-canonical Notch ligand 1 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of DLK1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr14:100,726,892...100,738,224
Ensembl chr14:100,725,705...100,738,224
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G |
DLST |
dihydrolipoamide S-succinyltransferase |
decreases expression |
ISO |
Thapsigargin results in decreased expression of DLST protein |
CTD |
PMID:35544339 |
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NCBI chr14:74,881,916...74,903,743
Ensembl chr14:74,881,891...74,903,743
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G |
DLX5 |
distal-less homeobox 5 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of DLX5 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 7:97,020,396...97,024,831
Ensembl chr 7:97,020,396...97,024,950
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G |
DMAC2L |
distal membrane arm assembly component 2 like |
decreases expression |
EXP |
Thapsigargin results in decreased expression of DMAC2L mRNA |
CTD |
PMID:22378314 |
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NCBI chr14:50,311,516...50,327,957
Ensembl chr14:50,312,324...50,335,558
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G |
DNAJA1 |
DnaJ heat shock protein family (Hsp40) member A1 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of DNAJA1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 9:33,025,273...33,039,907
Ensembl chr 9:33,025,273...33,039,907
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G |
DNAJA3 |
DnaJ heat shock protein family (Hsp40) member A3 |
increases expression |
EXP |
Thapsigargin results in increased expression of DNAJA3 mRNA |
CTD |
PMID:22378314 |
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NCBI chr16:4,425,868...4,456,775
Ensembl chr16:4,425,805...4,456,775
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G |
DNAJB11 |
DnaJ heat shock protein family (Hsp40) member B11 |
multiple interactions increases expression decreases expression |
EXP ISO |
4-methoxycinnamate methyl ester promotes the reaction [Thapsigargin results in decreased expression of DNAJB11 mRNA]; [DNAJB11 protein results in decreased transport of Calcium] which results in increased susceptibility to Thapsigargin; caffeic acid promotes the reaction [Thapsigargin results in decreased expression of DNAJB11 mRNA] Thapsigargin results in increased expression of DNAJB11 protein Thapsigargin results in increased expression of DNAJB11 mRNA; Thapsigargin results in increased expression of DNAJB11 protein |
CTD |
PMID:19442820 PMID:22378314 PMID:26085089 PMID:29453283 PMID:35544339 |
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NCBI chr 3:186,570,720...186,585,793
Ensembl chr 3:186,567,403...186,585,800
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G |
DNAJB9 |
DnaJ heat shock protein family (Hsp40) member B9 |
increases expression |
EXP ISO |
Thapsigargin results in increased expression of DNAJB9 mRNA |
CTD |
PMID:19135031 PMID:22378314 PMID:23123503 PMID:29453283 |
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NCBI chr 7:108,569,874...108,574,850
Ensembl chr 7:108,569,867...108,574,850
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G |
DNAJC1 |
DnaJ heat shock protein family (Hsp40) member C1 |
affects expression |
EXP |
Thapsigargin affects the expression of DNAJC1 mRNA |
CTD |
PMID:24247028 |
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NCBI chr10:21,756,548...22,003,730
Ensembl chr10:21,756,548...22,003,769
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G |
DNAJC10 |
DnaJ heat shock protein family (Hsp40) member C10 |
increases expression |
EXP |
Thapsigargin results in increased expression of DNAJC10 mRNA; Thapsigargin results in increased expression of DNAJC10 protein |
CTD |
PMID:17353921 PMID:29453283 |
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NCBI chr 2:182,716,257...182,794,464
Ensembl chr 2:182,716,255...182,794,464
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G |
DNAJC3 |
DnaJ heat shock protein family (Hsp40) member C3 |
increases expression multiple interactions |
EXP |
Thapsigargin results in increased expression of DNAJC3 mRNA; Thapsigargin results in increased expression of DNAJC3 protein [DNAJC3 protein results in decreased transport of Calcium] which results in increased susceptibility to Thapsigargin |
CTD |
PMID:19135031 PMID:26085089 PMID:29453283 |
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NCBI chr13:95,677,139...95,794,988
Ensembl chr13:95,677,139...95,794,988
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G |
DNASE2 |
deoxyribonuclease 2, lysosomal |
increases expression |
EXP |
Thapsigargin results in increased expression of DNASE2 mRNA |
CTD |
PMID:22378314 |
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NCBI chr19:12,875,209...12,881,449
Ensembl chr19:12,875,209...12,881,595
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G |
DNHD1 |
dynein heavy chain domain 1 |
increases expression |
EXP |
Thapsigargin results in increased expression of DNHD1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr11:6,497,280...6,572,020
Ensembl chr11:6,497,260...6,593,758
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G |
DNM1L |
dynamin 1 like |
increases expression |
EXP |
Thapsigargin results in increased expression of DNM1L mRNA |
CTD |
PMID:28940366 |
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NCBI chr12:32,679,301...32,745,650
Ensembl chr12:32,679,200...32,745,650
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G |
DNMT1 |
DNA methyltransferase 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of DNMT1 protein |
CTD |
PMID:24648495 |
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NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,342...10,231,286
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G |
DNMT3A |
DNA methyltransferase 3 alpha |
decreases expression |
ISO |
Thapsigargin results in decreased expression of DNMT3A protein |
CTD |
PMID:35544339 |
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NCBI chr 2:25,227,874...25,342,590
Ensembl chr 2:25,227,855...25,342,590
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G |
DOCK7 |
dedicator of cytokinesis 7 |
increases expression |
ISO |
Thapsigargin results in increased expression of DOCK7 protein |
CTD |
PMID:24648495 |
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NCBI chr 1:62,454,726...62,688,386
Ensembl chr 1:62,454,298...62,688,386
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G |
DPF1 |
double PHD fingers 1 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of DPF1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr19:38,211,006...38,229,695
Ensembl chr19:38,211,006...38,229,714
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G |
DPH5 |
diphthamide biosynthesis 5 |
increases expression |
EXP |
Thapsigargin results in increased expression of DPH5 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 1:100,989,623...101,025,784
Ensembl chr 1:100,989,623...101,026,088
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G |
DPYSL3 |
dihydropyrimidinase like 3 |
decreases expression |
EXP ISO |
Thapsigargin results in decreased expression of DPYSL3 mRNA Thapsigargin results in decreased expression of DPYSL3 protein |
CTD |
PMID:22378314 PMID:35544339 |
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NCBI chr 5:147,390,808...147,510,068
Ensembl chr 5:147,390,808...147,510,068
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G |
DPYSL4 |
dihydropyrimidinase like 4 |
multiple interactions increases expression |
EXP |
4-methoxycinnamate methyl ester promotes the reaction [Thapsigargin results in increased expression of DPYSL4 mRNA]; caffeic acid promotes the reaction [Thapsigargin results in increased expression of DPYSL4 mRNA]; Drugs, Chinese Herbal promotes the reaction [Thapsigargin results in increased expression of DPYSL4 mRNA] |
CTD |
PMID:19442820 |
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NCBI chr10:132,186,948...132,205,759
Ensembl chr10:132,186,948...132,205,759
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G |
DPYSL5 |
dihydropyrimidinase like 5 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of DPYSL5 protein |
CTD |
PMID:35544339 |
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NCBI chr 2:26,847,995...26,950,351
Ensembl chr 2:26,847,747...26,950,351
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G |
DSCC1 |
DNA replication and sister chromatid cohesion 1 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of DSCC1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 8:119,833,976...119,855,894
Ensembl chr 8:119,833,976...119,855,894
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G |
DSE |
dermatan sulfate epimerase |
decreases expression |
ISO |
Thapsigargin results in decreased expression of DSE protein |
CTD |
PMID:24648495 |
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NCBI chr 6:116,254,171...116,444,861
Ensembl chr 6:116,254,173...116,444,861
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G |
DTL |
denticleless E3 ubiquitin protein ligase homolog |
decreases expression |
EXP |
Thapsigargin results in decreased expression of DTL mRNA |
CTD |
PMID:22378314 |
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NCBI chr 1:212,035,748...212,105,013
Ensembl chr 1:212,035,553...212,107,400
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G |
DTNA |
dystrobrevin alpha |
decreases expression |
EXP |
Thapsigargin results in decreased expression of DTNA mRNA |
CTD |
PMID:22378314 |
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NCBI chr18:34,493,312...34,891,844
Ensembl chr18:34,493,291...34,891,844
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G |
DUSP1 |
dual specificity phosphatase 1 |
increases expression |
EXP |
Thapsigargin results in increased expression of DUSP1 mRNA |
CTD |
PMID:29453283 |
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NCBI chr 5:172,768,096...172,771,195
Ensembl chr 5:172,768,096...172,771,195
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G |
DUSP26 |
dual specificity phosphatase 26 |
increases expression |
EXP |
Thapsigargin results in increased expression of DUSP26 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 8:33,591,330...33,600,023
Ensembl chr 8:33,591,330...33,600,023
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G |
DUSP5 |
dual specificity phosphatase 5 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of DUSP5 mRNA |
CTD |
PMID:29453283 |
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NCBI chr10:110,497,907...110,511,533
Ensembl chr10:110,497,907...110,511,533
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G |
DUSP6 |
dual specificity phosphatase 6 |
increases expression decreases expression |
EXP |
Thapsigargin results in increased expression of DUSP6 mRNA Thapsigargin results in decreased expression of DUSP6 mRNA |
CTD |
PMID:22378314 PMID:24247028 |
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NCBI chr12:89,347,235...89,352,501
Ensembl chr12:89,347,235...89,352,501
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G |
DUT |
deoxyuridine triphosphatase |
decreases expression |
EXP ISO |
Thapsigargin results in decreased expression of DUT mRNA Thapsigargin results in decreased expression of DUT protein |
CTD |
PMID:22378314 PMID:24648495 |
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NCBI chr15:48,331,095...48,343,373
Ensembl chr15:48,331,011...48,343,373
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G |
DUXAP10 |
double homeobox A pseudogene 10 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of DUXAP10 mRNA |
CTD |
PMID:22378314 |
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NCBI chr14:19,294,785...19,337,674
Ensembl chr14:19,295,306...19,295,921 Ensembl chr14:19,295,306...19,295,921
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G |
DYM |
dymeclin |
decreases expression |
ISO |
Thapsigargin results in decreased expression of DYM protein |
CTD |
PMID:24648495 |
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NCBI chr18:49,036,387...49,460,645
Ensembl chr18:49,036,387...49,461,347
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G |
DYNC1H1 |
dynein cytoplasmic 1 heavy chain 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of DYNC1H1 protein |
CTD |
PMID:35544339 |
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NCBI chr14:101,964,573...102,056,443
Ensembl chr14:101,964,573...102,056,443
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G |
DYNC1I1 |
dynein cytoplasmic 1 intermediate chain 1 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of DYNC1I1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 7:95,772,554...96,110,322
Ensembl chr 7:95,772,506...96,110,322
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G |
DYNC2I2 |
dynein 2 intermediate chain 2 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of DYNC2I2 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 9:128,633,653...128,684,460
Ensembl chr 9:128,633,653...128,656,847
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G |
DYRK4 |
dual specificity tyrosine phosphorylation regulated kinase 4 |
increases expression |
EXP |
Thapsigargin results in increased expression of DYRK4 mRNA |
CTD |
PMID:22378314 |
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NCBI chr12:4,562,208...4,613,875
Ensembl chr12:4,562,208...4,615,302
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G |
E2F1 |
E2F transcription factor 1 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of E2F1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr20:33,675,477...33,686,385
Ensembl chr20:33,675,477...33,686,385
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G |
E2F2 |
E2F transcription factor 2 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of E2F2 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 1:23,505,212...23,531,233
Ensembl chr 1:23,506,438...23,531,233
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G |
E2F7 |
E2F transcription factor 7 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of E2F7 mRNA |
CTD |
PMID:22378314 |
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NCBI chr12:77,021,251...77,065,569
Ensembl chr12:77,021,248...77,065,569
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G |
EARS2 |
glutamyl-tRNA synthetase 2, mitochondrial |
decreases expression |
EXP |
Thapsigargin results in decreased expression of EARS2 mRNA |
CTD |
PMID:29453283 |
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NCBI chr16:23,520,754...23,557,375
Ensembl chr16:23,520,754...23,557,731
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G |
EBF1 |
EBF transcription factor 1 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of EBF1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 5:158,695,920...159,099,916
Ensembl chr 5:158,695,920...159,099,916
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G |
ECH1 |
enoyl-CoA hydratase 1 |
increases expression |
EXP |
Thapsigargin results in increased expression of ECH1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr19:38,815,422...38,831,794
Ensembl chr19:38,815,422...38,831,841
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G |
EDC4 |
enhancer of mRNA decapping 4 |
increases expression |
ISO |
Thapsigargin results in increased expression of EDC4 protein |
CTD |
PMID:24648495 |
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NCBI chr16:67,873,052...67,884,499
Ensembl chr16:67,873,052...67,884,499
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G |
EDEM1 |
ER degradation enhancing alpha-mannosidase like protein 1 |
increases expression |
EXP |
Thapsigargin results in increased expression of EDEM1 mRNA |
CTD |
PMID:22378314 PMID:27587023 |
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NCBI chr 3:5,187,707...5,219,958
Ensembl chr 3:5,187,646...5,219,958
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G |
EEF1A1 |
eukaryotic translation elongation factor 1 alpha 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of EEF1A1 protein |
CTD |
PMID:35544339 |
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NCBI chr 6:73,515,750...73,521,032
Ensembl chr 6:73,489,308...73,525,587
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G |
EEF1A2 |
eukaryotic translation elongation factor 1 alpha 2 |
increases expression |
ISO |
Thapsigargin results in increased expression of EEF1A2 protein |
CTD |
PMID:35544339 |
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NCBI chr20:63,488,014...63,499,083
Ensembl chr20:63,488,013...63,499,239
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G |
EEF1AKMT1 |
EEF1A lysine methyltransferase 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of EEF1AKMT1 protein |
CTD |
PMID:24648495 |
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NCBI chr13:20,728,731...20,773,961
Ensembl chr13:20,728,731...20,773,961
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G |
EEF1D |
eukaryotic translation elongation factor 1 delta |
decreases expression |
ISO |
Thapsigargin results in decreased expression of EEF1D protein |
CTD |
PMID:35544339 |
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NCBI chr 8:143,579,728...143,597,415
Ensembl chr 8:143,579,697...143,599,541
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G |
EEF2 |
eukaryotic translation elongation factor 2 |
increases expression |
ISO |
Thapsigargin results in increased expression of EEF2 protein |
CTD |
PMID:35544339 |
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NCBI chr19:3,976,056...3,985,463
Ensembl chr19:3,976,056...3,985,463
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G |
EEPD1 |
endonuclease/exonuclease/phosphatase family domain containing 1 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of EEPD1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 7:36,153,254...36,301,538
Ensembl chr 7:36,153,254...36,301,538
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G |
EFR3A |
EFR3 homolog A |
decreases expression |
ISO |
Thapsigargin results in decreased expression of EFR3A protein |
CTD |
PMID:24648495 |
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NCBI chr 8:131,904,093...132,013,642
Ensembl chr 8:131,904,093...132,013,642
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G |
EGF |
epidermal growth factor |
multiple interactions |
EXP |
Thapsigargin inhibits the reaction [EGF protein affects the localization of PRKCB protein] |
CTD |
PMID:17991733 |
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NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766
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G |
EGFR |
epidermal growth factor receptor |
increases expression |
ISO |
Thapsigargin results in increased expression of EGFR protein |
CTD |
PMID:24648495 |
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NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628
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G |
EGR1 |
early growth response 1 |
increases expression decreases expression |
ISO EXP |
Thapsigargin results in increased expression of EGR1 mRNA Thapsigargin results in decreased expression of EGR1 mRNA |
CTD |
PMID:8764118 PMID:21694771 PMID:22378314 |
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NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303
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G |
EGR2 |
early growth response 2 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of EGR2 mRNA |
CTD |
PMID:20830808 |
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NCBI chr10:62,811,996...62,819,167
Ensembl chr10:62,811,996...62,819,167
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G |
EIF1 |
eukaryotic translation initiation factor 1 |
increases expression |
EXP |
Thapsigargin results in increased expression of EIF1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr17:41,688,885...41,692,668
Ensembl chr17:41,688,885...41,692,668
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G |
EIF2A |
eukaryotic translation initiation factor 2A |
multiple interactions increases expression increases phosphorylation |
EXP ISO |
Doxorubicin promotes the reaction [Thapsigargin results in increased phosphorylation of EIF2A protein] Thapsigargin results in increased expression of EIF2A mRNA Thapsigargin promotes the reaction [EIF2AK3 protein results in increased phosphorylation of EIF2A protein] |
CTD |
PMID:12606582 PMID:16298333 PMID:17283163 PMID:17353921 PMID:19285962 PMID:19428936 PMID:20589738 PMID:22378314 More...
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NCBI chr 3:150,546,787...150,586,016
Ensembl chr 3:150,546,678...150,586,016
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G |
EIF2AK2 |
eukaryotic translation initiation factor 2 alpha kinase 2 |
multiple interactions increases phosphorylation |
ISO |
imoxin inhibits the reaction [Thapsigargin results in increased phosphorylation of EIF2AK2 protein] |
CTD |
PMID:24150608 |
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NCBI chr 2:37,099,210...37,156,980
Ensembl chr 2:37,099,210...37,157,522
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G |
EIF2AK3 |
eukaryotic translation initiation factor 2 alpha kinase 3 |
multiple interactions increases acetylation increases phosphorylation increases expression increases response to substance |
EXP ISO |
1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea inhibits the reaction [Thapsigargin results in increased phosphorylation of EIF2AK3 protein]; 2-(4-chlorophenoxy)-N-(4-(2-(4-chlorophenoxy)acetamido)cyclohexyl)acetamide promotes the reaction [Thapsigargin results in increased phosphorylation of EIF2AK3 protein]; demethoxycurcumin analog inhibits the reaction [Thapsigargin results in increased phosphorylation of EIF2AK3 protein]; EIF2AK3 mutant form inhibits the reaction [Thapsigargin results in increased phosphorylation of EIF2S1 protein]; EIF2AK3 promotes the reaction [Thapsigargin results in increased expression of DDIT3 protein]; EIF2AK3 promotes the reaction [Thapsigargin results in increased expression of HSPA5 protein]; Thapsigargin promotes the reaction [pterostilbene results in increased phosphorylation of EIF2AK3 protein] glucose promotes the reaction [thapsigargin increases phosphorylation of Eif2ak3 protein in cardiac muscle cells] Thapsigargin results in increased acetylation of EIF2AK3 protein Thapsigargin results in increased expression of EIF2AK3 mRNA; Thapsigargin results in increased expression of EIF2AK3 protein; Thapsigargin results in increased expression of EIF2AK3 protein modified form EIF2AK3 gene mutant form inhibits the reaction [Thapsigargin results in increased phosphorylation of EIF2S1 protein]; shikonin inhibits the reaction [Thapsigargin results in increased phosphorylation of EIF2AK3 protein]; Thapsigargin inhibits the reaction [dapagliflozin inhibits the reaction [IL1B protein results in increased expression of EIF2AK3 mRNA]] 1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea inhibits the reaction [Thapsigargin results in increased phosphorylation of EIF2AK3 protein]; [Thapsigargin co-treated with HRAS protein] results in increased expression of EIF2AK3 protein; EIF2AK3 gene mutant form inhibits the reaction [Thapsigargin results in increased expression of IBTK mRNA alternative form]; PTPN1 gene mutant form promotes the reaction [Thapsigargin results in increased activity of and results in increased phosphorylation of EIF2AK3 protein]; Thapsigargin promotes the reaction [EIF2AK3 protein results in increased phosphorylation of EIF2A protein]; Thapsigargin results in increased activity of and results in increased phosphorylation of EIF2AK3 protein EIF2AK3 gene mutant form results in increased susceptibility to Thapsigargin |
CTD RGD |
PMID:16324875 PMID:17283163 PMID:17963750 PMID:20022965 PMID:22378314 PMID:22509299 PMID:23576437 PMID:23741617 PMID:24150608 PMID:24224909 PMID:24648495 PMID:24865413 PMID:24898257 PMID:25341683 PMID:26264395 PMID:27358234 PMID:29653943 PMID:30796460 PMID:35028790 PMID:37741535 PMID:36044268 More...
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RGD:156430337 |
NCBI chr 2:88,556,741...88,628,145
Ensembl chr 2:88,556,741...88,691,518
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G |
EIF2S1 |
eukaryotic translation initiation factor 2 subunit alpha |
multiple interactions decreases phosphorylation increases expression increases phosphorylation decreases response to substance |
EXP ISO |
1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea inhibits the reaction [Thapsigargin results in increased phosphorylation of EIF2S1 protein]; EIF2AK3 mutant form inhibits the reaction [Thapsigargin results in increased phosphorylation of EIF2S1 protein]; Luteolin inhibits the reaction [Thapsigargin results in increased phosphorylation of EIF2S1 protein] Thapsigargin results in decreased phosphorylation of EIF2S1 protein Thapsigargin results in increased expression of EIF2S1 mRNA 1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea inhibits the reaction [Thapsigargin results in increased phosphorylation of EIF2S1 protein]; EIF2S1 protein modified form affects the reaction [Thapsigargin results in increased expression of ATF4 mRNA]; EIF2S1 protein modified form affects the reaction [Thapsigargin results in increased expression of DDIT3 mRNA]; EIF2S1 protein modified form affects the reaction [Thapsigargin results in increased expression of DDIT3 protein]; EIF2S1 protein modified form affects the reaction [Thapsigargin results in increased expression of PPP1R15A mRNA]; EIF2S1 protein modified form affects the reaction [Thapsigargin results in increased expression of PPP1R15A protein]; EIF2S1 protein mutant form inhibits the reaction [Thapsigargin results in decreased expression of TIMM17A protein]; EIF2S1 protein mutant form inhibits the reaction [Thapsigargin results in increased expression of IBTK mRNA alternative form]; PTPN1 gene mutant form promotes the reaction [Thapsigargin results in increased activity of and results in increased phosphorylation of EIF2S1 protein]; Thapsigargin inhibits the reaction [7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid inhibits the reaction [Palmitic Acid results in increased phosphorylation of EIF2S1 protein]]; Thapsigargin results in increased activity of and results in increased phosphorylation of EIF2S1 protein Thapsigargin results in increased expression of EIF2S1 protein modified form EIF2S1 protein mutant form results in decreased susceptibility to Thapsigargin EIF2AK3 gene mutant form inhibits the reaction [Thapsigargin results in increased phosphorylation of EIF2S1 protein]; salubrinal inhibits the reaction [Thapsigargin results in increased expression of EIF2S1 mRNA]; shikonin inhibits the reaction [Thapsigargin results in increased phosphorylation of EIF2S1 protein] |
CTD |
PMID:16324875 PMID:17553788 PMID:19233273 PMID:20022965 PMID:22509299 PMID:23576437 PMID:23690448 PMID:23741617 PMID:24150608 PMID:24224909 PMID:24315374 PMID:24648495 PMID:27587023 PMID:28844859 PMID:29109149 PMID:29414781 PMID:30508555 PMID:32357311 PMID:32407927 PMID:32578922 PMID:35028790 More...
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NCBI chr14:67,360,328...67,386,516
Ensembl chr14:67,360,328...67,386,516
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G |
EIF2S2 |
eukaryotic translation initiation factor 2 subunit beta |
affects expression increases expression |
EXP |
Thapsigargin affects the expression of EIF2S2 mRNA Thapsigargin results in increased expression of EIF2S2 mRNA |
CTD |
PMID:22378314 PMID:24247028 |
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NCBI chr20:34,088,309...34,112,243
Ensembl chr20:34,088,309...34,112,243
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G |
EIF3A |
eukaryotic translation initiation factor 3 subunit A |
increases expression |
ISO |
Thapsigargin results in increased expression of EIF3A protein |
CTD |
PMID:24648495 |
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NCBI chr10:119,033,670...119,080,817
Ensembl chr10:119,033,670...119,080,817
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G |
EIF3B |
eukaryotic translation initiation factor 3 subunit B |
increases expression |
ISO |
Thapsigargin results in increased expression of EIF3B protein |
CTD |
PMID:35544339 |
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NCBI chr 7:2,354,086...2,380,745
Ensembl chr 7:2,354,086...2,380,745
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G |
EIF3D |
eukaryotic translation initiation factor 3 subunit D |
increases expression |
ISO |
Thapsigargin results in increased expression of EIF3D protein |
CTD |
PMID:35544339 |
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NCBI chr22:36,510,855...36,529,166
Ensembl chr22:36,510,855...36,529,184
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G |
EIF3I |
eukaryotic translation initiation factor 3 subunit I |
decreases expression increases expression |
EXP ISO |
Thapsigargin results in decreased expression of EIF3I protein Thapsigargin results in increased expression of EIF3I protein |
CTD |
PMID:21692457 PMID:35544339 |
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NCBI chr 1:32,222,407...32,236,170
Ensembl chr 1:32,221,077...32,245,397
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G |
EIF4A2 |
eukaryotic translation initiation factor 4A2 |
increases expression |
ISO |
Thapsigargin results in increased expression of EIF4A2 protein |
CTD |
PMID:35544339 |
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NCBI chr 3:186,783,577...186,789,897
Ensembl chr 3:186,783,205...186,789,897
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G |
EIF4E |
eukaryotic translation initiation factor 4E |
decreases expression increases expression |
ISO |
Thapsigargin results in decreased expression of EIF4E mRNA; Thapsigargin results in decreased expression of EIF4E protein Thapsigargin results in increased expression of EIF4E protein |
CTD |
PMID:24648495 PMID:35544339 |
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NCBI chr 4:98,879,276...98,929,133
Ensembl chr 4:98,879,276...98,929,133
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G |
EIF4EBP1 |
eukaryotic translation initiation factor 4E binding protein 1 |
increases expression |
EXP |
Thapsigargin results in increased expression of EIF4EBP1 mRNA; Thapsigargin results in increased expression of EIF4EBP1 protein |
CTD |
PMID:29453283 |
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NCBI chr 8:38,030,534...38,060,365
Ensembl chr 8:38,030,534...38,060,365
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G |
EIF4H |
eukaryotic translation initiation factor 4H |
decreases expression |
ISO |
Thapsigargin results in decreased expression of EIF4H protein |
CTD |
PMID:35544339 |
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NCBI chr 7:74,174,356...74,197,096
Ensembl chr 7:74,174,231...74,197,122
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G |
EIF5 |
eukaryotic translation initiation factor 5 |
increases expression |
ISO |
Thapsigargin results in increased expression of EIF5 protein |
CTD |
PMID:35544339 |
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NCBI chr14:103,334,237...103,345,025
Ensembl chr14:103,333,544...103,345,025
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G |
EIF5A |
eukaryotic translation initiation factor 5A |
affects response to substance |
EXP |
EIF5A protein affects the susceptibility to Thapsigargin |
CTD |
PMID:20376341 |
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NCBI chr17:7,306,999...7,312,463
Ensembl chr17:7,306,999...7,312,463
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G |
EIF5B |
eukaryotic translation initiation factor 5B |
increases expression |
ISO |
Thapsigargin results in increased expression of EIF5B protein |
CTD |
PMID:24648495 |
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NCBI chr 2:99,337,389...99,401,326
Ensembl chr 2:99,337,389...99,401,326
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G |
ELAVL1 |
ELAV like RNA binding protein 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ELAVL1 protein |
CTD |
PMID:35544339 |
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NCBI chr19:7,958,573...8,005,641
Ensembl chr19:7,958,573...8,005,659
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G |
ELF1 |
E74 like ETS transcription factor 1 |
increases expression |
EXP |
Thapsigargin results in increased expression of ELF1 mRNA |
CTD |
PMID:29453283 |
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NCBI chr13:40,931,919...41,061,386
Ensembl chr13:40,931,919...41,061,440
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G |
ELF3 |
E74 like ETS transcription factor 3 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of ELF3 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 1:202,010,587...202,017,183
Ensembl chr 1:202,007,945...202,017,183
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G |
ELMO2 |
engulfment and cell motility 2 |
multiple interactions |
EXP |
4-methoxycinnamate methyl ester promotes the reaction [Thapsigargin results in decreased expression of ELMO2 mRNA]; caffeic acid promotes the reaction [Thapsigargin results in decreased expression of ELMO2 mRNA]; Drugs, Chinese Herbal promotes the reaction [Thapsigargin results in decreased expression of ELMO2 mRNA] |
CTD |
PMID:19442820 |
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NCBI chr20:46,366,050...46,406,615
Ensembl chr20:46,366,050...46,432,985
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G |
ELOVL2 |
ELOVL fatty acid elongase 2 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of ELOVL2 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 6:10,980,759...11,044,305
Ensembl chr 6:10,980,759...11,044,305
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G |
EMC4 |
ER membrane protein complex subunit 4 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of EMC4 protein |
CTD |
PMID:24648495 |
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NCBI chr15:34,225,016...34,230,156
Ensembl chr15:34,225,013...34,230,156
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G |
EMILIN2 |
elastin microfibril interfacer 2 |
increases expression |
EXP |
Thapsigargin results in increased expression of EMILIN2 mRNA |
CTD |
PMID:29453283 |
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NCBI chr18:2,846,232...2,916,003
Ensembl chr18:2,847,006...2,916,003
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G |
EML2 |
EMAP like 2 |
increases expression |
EXP |
Thapsigargin results in increased expression of EML2 mRNA |
CTD |
PMID:22378314 |
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NCBI chr19:45,609,400...45,645,629
Ensembl chr19:45,606,994...45,645,602
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G |
ENC1 |
ectodermal-neural cortex 1 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of ENC1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 5:74,627,409...74,640,728
Ensembl chr 5:74,627,406...74,641,424
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G |
ENDOG |
endonuclease G |
decreases expression |
EXP |
Thapsigargin results in decreased expression of ENDOG mRNA |
CTD |
PMID:22378314 |
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NCBI chr 9:128,818,500...128,822,676
Ensembl chr 9:128,818,500...128,822,676
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G |
ENKD1 |
enkurin domain containing 1 |
increases expression |
EXP |
Thapsigargin results in increased expression of ENKD1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr16:67,662,945...67,666,750
Ensembl chr16:67,662,945...67,667,265
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G |
ENO1 |
enolase 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of ENO1 protein |
CTD |
PMID:35544339 |
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NCBI chr 1:8,861,000...8,878,686
Ensembl chr 1:8,861,000...8,879,190
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G |
ENO2 |
enolase 2 |
increases expression |
EXP |
Thapsigargin results in increased expression of ENO2 mRNA |
CTD |
PMID:29453283 |
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NCBI chr12:6,914,580...6,923,697
Ensembl chr12:6,913,745...6,923,698
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G |
ENO3 |
enolase 3 |
increases expression |
EXP |
Thapsigargin results in increased expression of ENO3 mRNA |
CTD |
PMID:22378314 |
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NCBI chr17:4,948,710...4,957,129
Ensembl chr17:4,948,092...4,957,131
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G |
ENPP2 |
ectonucleotide pyrophosphatase/phosphodiesterase 2 |
decreases expression increases expression |
EXP |
Thapsigargin results in decreased expression of ENPP2 mRNA Thapsigargin results in increased expression of ENPP2 mRNA |
CTD |
PMID:22378314 PMID:29453283 |
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NCBI chr 8:119,557,086...119,673,390
Ensembl chr 8:119,557,086...119,673,453
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G |
ENTPD5 |
ectonucleoside triphosphate diphosphohydrolase 5 (inactive) |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ENTPD5 protein |
CTD |
PMID:24648495 |
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NCBI chr14:73,955,329...74,019,288
Ensembl chr14:73,958,010...74,019,399
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G |
EOGT |
EGF domain specific O-linked N-acetylglucosamine transferase |
increases expression |
ISO |
Thapsigargin results in increased expression of EOGT protein |
CTD |
PMID:35544339 |
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NCBI chr 3:68,975,225...69,013,684
Ensembl chr 3:68,975,217...69,013,684
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G |
EP400 |
E1A binding protein p400 |
increases expression |
ISO |
Thapsigargin results in increased expression of EP400 protein |
CTD |
PMID:24648495 |
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NCBI chr12:131,949,942...132,080,460
Ensembl chr12:131,949,942...132,080,460
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G |
EPAS1 |
endothelial PAS domain protein 1 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of EPAS1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 2:46,297,407...46,386,697
Ensembl chr 2:46,293,667...46,386,697
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G |
EPB41L4A-AS1 |
EPB41L4A antisense RNA 1 |
increases expression |
EXP |
Thapsigargin results in increased expression of EPB41L4A-AS1 mRNA |
CTD |
PMID:22378314 PMID:29453283 |
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NCBI chr 5:112,160,526...112,162,501
Ensembl chr 5:112,160,526...112,164,818
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G |
EPHX4 |
epoxide hydrolase 4 |
increases expression |
EXP |
Thapsigargin results in increased expression of EPHX4 mRNA |
CTD |
PMID:29453283 |
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NCBI chr 1:92,029,985...92,063,538
Ensembl chr 1:92,029,985...92,063,538
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G |
EPRS1 |
glutamyl-prolyl-tRNA synthetase 1 |
increases expression |
EXP ISO |
Thapsigargin results in increased expression of EPRS1 mRNA Thapsigargin results in increased expression of EPRS1 protein |
CTD |
PMID:22378314 PMID:24648495 |
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NCBI chr 1:219,968,600...220,046,505
Ensembl chr 1:219,968,600...220,046,530
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G |
EPS8 |
EGFR pathway substrate 8, signaling adaptor |
decreases expression |
ISO |
Thapsigargin results in decreased expression of EPS8 protein |
CTD |
PMID:35544339 |
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NCBI chr12:15,620,134...15,789,388
Ensembl chr12:15,620,134...15,882,329
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G |
ERAP1 |
endoplasmic reticulum aminopeptidase 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ERAP1 protein |
CTD |
PMID:35544339 |
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NCBI chr 5:96,760,813...96,935,854
Ensembl chr 5:96,760,810...96,808,100
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G |
ERAP2 |
endoplasmic reticulum aminopeptidase 2 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of ERAP2 mRNA |
CTD |
PMID:29453283 |
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NCBI chr 5:96,875,939...96,919,716
Ensembl chr 5:96,875,986...96,919,703
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G |
ERCC6L |
ERCC excision repair 6 like, spindle assembly checkpoint helicase |
decreases expression |
EXP |
Thapsigargin results in decreased expression of ERCC6L mRNA |
CTD |
PMID:22378314 |
|
NCBI chr X:72,204,665...72,239,027
Ensembl chr X:72,204,657...72,239,027
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G |
ERF |
ETS2 repressor factor |
multiple interactions increases expression |
EXP |
caffeic acid promotes the reaction [Thapsigargin results in increased expression of ERF mRNA]; Drugs, Chinese Herbal promotes the reaction [Thapsigargin results in increased expression of ERF mRNA] |
CTD |
PMID:19442820 |
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NCBI chr19:42,247,569...42,255,128
Ensembl chr19:42,247,569...42,255,128
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G |
ERLIN2 |
ER lipid raft associated 2 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ERLIN2 protein |
CTD |
PMID:35544339 |
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NCBI chr 8:37,736,634...37,758,422
Ensembl chr 8:37,736,601...37,758,422
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G |
ERN1 |
endoplasmic reticulum to nucleus signaling 1 |
multiple interactions affects splicing increases expression increases phosphorylation |
ISO EXP |
1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea inhibits the reaction [Thapsigargin results in increased phosphorylation of ERN1 protein]; [Thapsigargin co-treated with HRAS protein] results in increased expression of ERN1 protein; Apigenin inhibits the reaction [Thapsigargin results in increased phosphorylation of ERN1 protein]; Thapsigargin inhibits the reaction [7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid inhibits the reaction [Palmitic Acid results in increased phosphorylation of ERN1 protein]] Thapsigargin affects the splicing of ERN1 mRNA Thapsigargin results in increased expression of ERN1 protein Thapsigargin results in increased expression of ERN1 mRNA; Thapsigargin results in increased expression of ERN1 protein; Thapsigargin results in increased expression of ERN1 protein modified form 1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea inhibits the reaction [Thapsigargin results in increased phosphorylation of ERN1 protein]; 4-phenylbutyric acid inhibits the reaction [Thapsigargin results in increased expression of ERN1 protein]; [Thapsigargin affects the splicing of ERN1 mRNA] which results in increased expression of ERN1 protein alternative form; BCL2L1 protein inhibits the reaction [Thapsigargin results in increased expression of ERN1 protein]; demethoxycurcumin analog inhibits the reaction [Thapsigargin results in increased phosphorylation of ERN1 protein]; EUK-134 inhibits the reaction [Thapsigargin results in increased expression of ERN1 protein]; Luteolin inhibits the reaction [Thapsigargin results in increased expression of and results in increased phosphorylation of ERN1 protein]; Thapsigargin results in increased expression of and results in increased phosphorylation of ERN1 protein |
CTD |
PMID:17963750 PMID:19139269 PMID:20493918 PMID:22378314 PMID:23576437 PMID:23885834 PMID:24224909 PMID:24638036 PMID:24898257 PMID:26264395 PMID:27587023 PMID:29414781 PMID:30796460 PMID:32407927 PMID:32535746 PMID:35033536 More...
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NCBI chr17:64,039,142...64,130,144
Ensembl chr17:64,039,080...64,130,819
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G |
ERO1A |
endoplasmic reticulum oxidoreductase 1 alpha |
increases expression multiple interactions |
ISO EXP |
Thapsigargin results in increased expression of ERO1A protein 2-(4-chlorophenoxy)-N-(4-(2-(4-chlorophenoxy)acetamido)cyclohexyl)acetamide inhibits the reaction [Thapsigargin results in increased expression of ERO1A protein] |
CTD |
PMID:28315715 PMID:35964836 |
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NCBI chr14:52,639,915...52,695,558
Ensembl chr14:52,639,915...52,695,900
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G |
ERO1B |
endoplasmic reticulum oxidoreductase 1 beta |
increases expression |
EXP |
Thapsigargin results in increased expression of ERO1B mRNA |
CTD |
PMID:22378314 |
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NCBI chr 1:236,215,101...236,281,958
Ensembl chr 1:236,214,681...236,282,019
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G |
ERP44 |
endoplasmic reticulum protein 44 |
increases expression |
EXP |
Thapsigargin results in increased expression of ERP44 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 9:99,979,185...100,099,000
Ensembl chr 9:99,979,185...100,099,052
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G |
ESD |
esterase D |
increases expression |
ISO |
Thapsigargin results in increased expression of ESD protein |
CTD |
PMID:35544339 |
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NCBI chr13:46,771,256...46,797,700
Ensembl chr13:46,771,256...46,797,420
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G |
ESF1 |
ESF1 nucleolar pre-rRNA processing protein homolog |
increases expression |
ISO |
Thapsigargin results in increased expression of ESF1 protein |
CTD |
PMID:24648495 |
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NCBI chr20:13,714,325...13,784,919
Ensembl chr20:13,714,322...13,784,919
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G |
ESRP1 |
epithelial splicing regulatory protein 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of ESRP1 protein |
CTD |
PMID:35544339 |
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NCBI chr 8:94,641,174...94,707,466
Ensembl chr 8:94,641,074...94,707,466
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G |
ESRRG |
estrogen related receptor gamma |
decreases expression |
EXP |
Thapsigargin results in decreased expression of ESRRG mRNA |
CTD |
PMID:22378314 |
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NCBI chr 1:216,503,246...217,137,702
Ensembl chr 1:216,503,246...217,137,755
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G |
ESYT1 |
extended synaptotagmin 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of ESYT1 protein |
CTD |
PMID:35544339 |
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NCBI chr12:56,128,267...56,144,674
Ensembl chr12:56,118,250...56,144,674
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G |
ETF1 |
eukaryotic translation termination factor 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of ETF1 protein |
CTD |
PMID:35544339 |
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NCBI chr 5:138,506,095...138,543,236
Ensembl chr 5:138,506,095...138,543,236
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G |
ETHE1 |
ETHE1 persulfide dioxygenase |
decreases expression |
ISO |
Thapsigargin results in decreased expression of ETHE1 protein |
CTD |
PMID:24648495 |
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NCBI chr19:43,506,719...43,527,201
Ensembl chr19:43,506,719...43,527,230
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G |
ETV4 |
ETS variant transcription factor 4 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of ETV4 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr17:43,527,846...43,546,340
Ensembl chr17:43,527,844...43,579,620
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G |
ETV5 |
ETS variant transcription factor 5 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of ETV5 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 3:186,046,314...186,109,089
Ensembl chr 3:186,046,314...186,110,318
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G |
EVI2A |
ecotropic viral integration site 2A |
increases expression |
EXP |
Thapsigargin results in increased expression of EVI2A mRNA |
CTD |
PMID:24247028 |
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NCBI chr17:31,316,410...31,321,622
Ensembl chr17:31,316,410...31,321,749
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G |
EXO1 |
exonuclease 1 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of EXO1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 1:241,847,986...241,889,939
Ensembl chr 1:241,847,967...241,895,148
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G |
EXOC4 |
exocyst complex component 4 |
increases expression |
ISO |
Thapsigargin results in increased expression of EXOC4 protein |
CTD |
PMID:24648495 |
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NCBI chr 7:133,253,078...134,100,951
Ensembl chr 7:133,253,072...134,067,137
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G |
EXOC6 |
exocyst complex component 6 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of EXOC6 protein |
CTD |
PMID:35544339 |
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NCBI chr10:92,826,831...93,059,490
Ensembl chr10:92,826,831...93,059,493
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G |
EXOSC2 |
exosome component 2 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of EXOSC2 mRNA |
CTD |
PMID:24247028 |
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NCBI chr 9:130,693,760...130,704,894
Ensembl chr 9:130,693,721...130,707,288
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G |
EXOSC7 |
exosome component 7 |
affects expression |
EXP |
Thapsigargin affects the expression of EXOSC7 mRNA |
CTD |
PMID:24247028 |
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NCBI chr 3:44,976,244...45,012,668
Ensembl chr 3:44,975,241...45,036,066
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G |
EXT2 |
exostosin glycosyltransferase 2 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of EXT2 protein |
CTD |
PMID:24648495 |
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NCBI chr11:44,095,678...44,251,962
Ensembl chr11:44,095,648...44,251,962
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G |
EYA1 |
EYA transcriptional coactivator and phosphatase 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of EYA1 protein |
CTD |
PMID:24648495 |
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NCBI chr 8:71,197,433...71,548,094
Ensembl chr 8:71,197,433...71,592,025
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G |
F2RL1 |
F2R like trypsin receptor 1 |
decreases expression increases expression |
ISO EXP |
Thapsigargin results in decreased expression of F2RL1 protein Thapsigargin results in increased expression of F2RL1 mRNA |
CTD |
PMID:24648495 PMID:29453283 |
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NCBI chr 5:76,819,030...76,835,315
Ensembl chr 5:76,818,933...76,835,315
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G |
FAAH |
fatty acid amide hydrolase |
increases expression |
ISO |
Thapsigargin results in increased expression of FAAH protein |
CTD |
PMID:35544339 |
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NCBI chr 1:46,394,317...46,413,845
Ensembl chr 1:46,394,317...46,413,848
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G |
FADS1 |
fatty acid desaturase 1 |
increases expression |
EXP ISO |
Thapsigargin results in increased expression of FADS1 mRNA Thapsigargin results in increased expression of FADS1 protein |
CTD |
PMID:29453283 PMID:35544339 |
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NCBI chr11:61,799,627...61,817,003
Ensembl chr11:61,799,627...61,829,318
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G |
FADS2 |
fatty acid desaturase 2 |
increases expression |
ISO |
Thapsigargin results in increased expression of FADS2 protein |
CTD |
PMID:35544339 |
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NCBI chr11:61,816,203...61,867,354
Ensembl chr11:61,792,980...61,867,354
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G |
FADS3 |
fatty acid desaturase 3 |
increases expression |
EXP |
Thapsigargin results in increased expression of FADS3 mRNA |
CTD |
PMID:22378314 |
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NCBI chr11:61,873,526...61,892,224
Ensembl chr11:61,873,519...61,892,051
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G |
FAM107B |
family with sequence similarity 107 member B |
increases expression decreases expression |
EXP ISO |
Thapsigargin results in increased expression of FAM107B mRNA Thapsigargin results in decreased expression of FAM107B protein |
CTD |
PMID:22378314 PMID:24648495 |
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NCBI chr10:14,518,557...14,774,897
Ensembl chr10:14,518,557...14,774,897
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G |
FAM118B |
family with sequence similarity 118 member B |
decreases expression |
ISO |
Thapsigargin results in decreased expression of FAM118B protein |
CTD |
PMID:24648495 |
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NCBI chr11:126,211,724...126,262,987
Ensembl chr11:126,211,724...126,262,984
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G |
FAM120A |
family with sequence similarity 120 member A |
decreases expression |
ISO |
Thapsigargin results in decreased expression of FAM120A protein |
CTD |
PMID:24648495 |
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NCBI chr 9:93,451,685...93,566,112
Ensembl chr 9:93,451,685...93,566,112
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G |
FAM120C |
family with sequence similarity 120 member C |
increases expression |
ISO |
Thapsigargin results in increased expression of FAM120C protein |
CTD |
PMID:24648495 |
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NCBI chr X:54,068,324...54,183,254
Ensembl chr X:54,068,324...54,183,281
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G |
FAM13B |
family with sequence similarity 13 member B |
increases expression |
EXP |
Thapsigargin results in increased expression of FAM13B mRNA |
CTD |
PMID:29453283 |
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NCBI chr 5:137,937,960...138,052,178
Ensembl chr 5:137,937,960...138,051,961
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G |
FAM174B |
family with sequence similarity 174 member B |
increases expression |
EXP |
Thapsigargin results in increased expression of FAM174B mRNA |
CTD |
PMID:29453283 |
|
NCBI chr15:92,617,448...92,655,775
Ensembl chr15:92,617,448...92,809,884
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G |
FAM193A |
family with sequence similarity 193 member A |
increases expression |
ISO |
Thapsigargin results in increased expression of FAM193A protein |
CTD |
PMID:24648495 |
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NCBI chr 4:2,535,375...2,732,573
Ensembl chr 4:2,536,647...2,732,573
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G |
FAM234A |
family with sequence similarity 234 member A |
decreases expression |
ISO |
Thapsigargin results in decreased expression of FAM234A protein |
CTD |
PMID:24648495 |
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NCBI chr16:234,821...269,963
Ensembl chr16:234,521...272,183
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G |
FAM234B |
family with sequence similarity 234 member B |
decreases expression |
ISO |
Thapsigargin results in decreased expression of FAM234B protein |
CTD |
PMID:35544339 |
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NCBI chr12:13,044,381...13,083,449
Ensembl chr12:13,044,381...13,142,521
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G |
FAM24B |
family with sequence similarity 24 member B |
increases expression |
EXP |
Thapsigargin results in increased expression of FAM24B mRNA |
CTD |
PMID:22378314 PMID:29453283 |
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NCBI chr10:122,849,078...122,879,641
Ensembl chr10:122,849,078...122,879,641
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G |
FAM3C |
FAM3 metabolism regulating signaling molecule C |
increases expression |
ISO |
Thapsigargin results in increased expression of FAM3C protein |
CTD |
PMID:35544339 |
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NCBI chr 7:121,348,878...121,396,396
Ensembl chr 7:121,348,878...121,396,364
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G |
FAM83D |
family with sequence similarity 83 member D |
decreases expression |
EXP |
Thapsigargin results in decreased expression of FAM83D mRNA |
CTD |
PMID:22378314 |
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NCBI chr20:38,926,417...38,953,106
Ensembl chr20:38,926,312...38,953,106
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G |
FANCI |
FA complementation group I |
decreases expression |
EXP |
Thapsigargin results in decreased expression of FANCI mRNA |
CTD |
PMID:22378314 |
|
NCBI chr15:89,243,979...89,317,259
Ensembl chr15:89,243,945...89,317,261
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G |
FAS |
Fas cell surface death receptor |
increases expression |
EXP |
Thapsigargin results in increased expression of FAS mRNA |
CTD |
PMID:33770205 |
|
NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605
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G |
FASN |
fatty acid synthase |
increases expression |
ISO |
Thapsigargin results in increased expression of FASN protein |
CTD |
PMID:35544339 |
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NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294
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G |
FBN2 |
fibrillin 2 |
increases expression |
EXP |
Thapsigargin results in increased expression of FBN2 mRNA |
CTD |
PMID:29453283 |
|
NCBI chr 5:128,257,909...128,538,245
Ensembl chr 5:128,257,909...128,659,185
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G |
FBP1 |
fructose-bisphosphatase 1 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of FBP1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 9:94,603,133...94,640,263
Ensembl chr 9:94,603,133...94,640,249
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G |
FBXO32 |
F-box protein 32 |
increases expression |
EXP |
Thapsigargin results in increased expression of FBXO32 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 8:123,497,889...123,541,206
Ensembl chr 8:123,497,889...123,541,206
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G |
FDFT1 |
farnesyl-diphosphate farnesyltransferase 1 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of FDFT1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 8:11,795,582...11,839,298
Ensembl chr 8:11,795,573...11,839,395
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G |
FDPS |
farnesyl diphosphate synthase |
increases expression |
ISO |
Thapsigargin results in increased expression of FDPS protein |
CTD |
PMID:35544339 |
|
NCBI chr 1:155,308,866...155,320,665
Ensembl chr 1:155,308,748...155,320,666
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G |
FDXR |
ferredoxin reductase |
increases expression |
EXP |
Thapsigargin results in increased expression of FDXR mRNA |
CTD |
PMID:22378314 |
|
NCBI chr17:74,862,497...74,872,994
Ensembl chr17:74,862,497...74,873,031
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G |
FEN1 |
flap structure-specific endonuclease 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of FEN1 protein |
CTD |
PMID:35544339 |
|
NCBI chr11:61,792,911...61,797,238
Ensembl chr11:61,792,911...61,797,238
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G |
FGF13 |
fibroblast growth factor 13 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of FGF13 mRNA |
CTD |
PMID:19442820 |
|
NCBI chr X:138,614,727...139,205,023
Ensembl chr X:138,614,727...139,222,777
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G |
FGF21 |
fibroblast growth factor 21 |
multiple interactions increases expression increases secretion |
ISO EXP |
indolo(3,2-b)carbazole inhibits the reaction [Thapsigargin results in increased expression of FGF21 mRNA]; N-(2-(3H-indol-3-yl)ethyl)-9-isopropyl-2-(5-methyl-3-pyridyl)purin-6-amine inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [Thapsigargin results in increased expression of FGF21 mRNA]]; Tetrachlorodibenzodioxin inhibits the reaction [Thapsigargin results in increased expression of FGF21 mRNA] Thapsigargin results in increased secretion of FGF21 protein |
CTD |
PMID:23123503 PMID:27226639 |
|
NCBI chr19:48,755,524...48,758,330
Ensembl chr19:48,755,524...48,758,333
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|
G |
FGGY |
FGGY carbohydrate kinase domain containing |
increases expression |
EXP |
Thapsigargin results in increased expression of FGGY mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 1:59,296,378...59,762,730
Ensembl chr 1:59,296,638...59,810,647
|
|
G |
FH |
fumarate hydratase |
decreases expression |
EXP |
Thapsigargin results in decreased expression of FH mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 1:241,497,603...241,519,755
Ensembl chr 1:241,497,511...241,519,799
|
|
G |
FICD |
FIC domain protein adenylyltransferase |
increases expression |
EXP |
Thapsigargin results in increased expression of FICD mRNA |
CTD |
PMID:22378314 |
|
NCBI chr12:108,515,277...108,521,210
Ensembl chr12:108,515,277...108,525,837
|
|
G |
FIGNL1 |
fidgetin like 1 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of FIGNL1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 7:50,444,133...50,450,350
Ensembl chr 7:50,444,128...50,450,390
|
|
G |
FILIP1L |
filamin A interacting protein 1 like |
increases expression |
ISO |
Thapsigargin results in increased expression of FILIP1L protein |
CTD |
PMID:24648495 |
|
NCBI chr 3:99,828,811...100,114,501
Ensembl chr 3:99,828,811...100,114,513
|
|
G |
FIS1 |
fission, mitochondrial 1 |
increases expression |
EXP |
Thapsigargin results in increased expression of FIS1 mRNA |
CTD |
PMID:28940366 |
|
NCBI chr 7:101,239,472...101,245,081
Ensembl chr 7:101,239,458...101,252,316
|
|
G |
FJX1 |
four-jointed box kinase 1 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of FJX1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr11:35,618,460...35,620,865
Ensembl chr11:35,618,460...35,620,865
|
|
G |
FKBP11 |
FKBP prolyl isomerase 11 |
increases expression |
EXP |
Thapsigargin results in increased expression of FKBP11 mRNA |
CTD |
PMID:22378314 PMID:29453283 |
|
NCBI chr12:48,921,963...48,939,034
Ensembl chr12:48,921,518...48,926,474
|
|
G |
FKBP2 |
FKBP prolyl isomerase 2 |
increases expression |
EXP |
Thapsigargin results in increased expression of FKBP2 mRNA |
CTD |
PMID:22378314 PMID:29453283 |
|
NCBI chr11:64,241,095...64,244,135
Ensembl chr11:64,241,003...64,244,132
|
|
G |
FKBP3 |
FKBP prolyl isomerase 3 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of FKBP3 protein |
CTD |
PMID:24648495 |
|
NCBI chr14:45,115,599...45,134,481
Ensembl chr14:45,115,599...45,135,319
|
|
G |
FLII |
FLII actin remodeling protein |
increases expression |
ISO |
Thapsigargin results in increased expression of FLII protein |
CTD |
PMID:24648495 |
|
NCBI chr17:18,244,815...18,259,022
Ensembl chr17:18,244,815...18,258,738
|
|
G |
FLOT2 |
flotillin 2 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of FLOT2 mRNA |
CTD |
PMID:29453283 |
|
NCBI chr17:28,879,339...28,897,733
Ensembl chr17:28,879,335...28,897,733
|
|
G |
FLRT2 |
fibronectin leucine rich transmembrane protein 2 |
decreases expression multiple interactions |
EXP |
Thapsigargin results in decreased expression of FLRT2 mRNA 4-methoxycinnamate methyl ester promotes the reaction [Thapsigargin results in decreased expression of FLRT2 mRNA]; caffeic acid promotes the reaction [Thapsigargin results in decreased expression of FLRT2 mRNA]; Drugs, Chinese Herbal promotes the reaction [Thapsigargin results in decreased expression of FLRT2 mRNA] |
CTD |
PMID:19442820 |
|
NCBI chr14:85,530,144...85,654,428
Ensembl chr14:85,530,144...85,654,428
|
|
G |
FLT4 |
fms related receptor tyrosine kinase 4 |
multiple interactions |
EXP |
4-methoxycinnamate methyl ester promotes the reaction [Thapsigargin results in decreased expression of FLT4 mRNA]; caffeic acid promotes the reaction [Thapsigargin results in decreased expression of FLT4 mRNA]; Drugs, Chinese Herbal promotes the reaction [Thapsigargin results in decreased expression of FLT4 mRNA] |
CTD |
PMID:19442820 |
|
NCBI chr 5:180,601,506...180,650,298
Ensembl chr 5:180,601,506...180,649,624
|
|
G |
FMR1 |
fragile X messenger ribonucleoprotein 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of FMR1 protein |
CTD |
PMID:35544339 |
|
NCBI chr X:147,911,919...147,951,125
Ensembl chr X:147,911,919...147,951,125
|
|
G |
FN1 |
fibronectin 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of FN1 protein |
CTD |
PMID:35544339 |
|
NCBI chr 2:215,360,865...215,436,068
Ensembl chr 2:215,360,440...215,436,073
|
|
G |
FNBP1L |
formin binding protein 1 like |
decreases expression |
ISO |
Thapsigargin results in decreased expression of FNBP1L protein |
CTD |
PMID:35544339 |
|
NCBI chr 1:93,448,118...93,554,661
Ensembl chr 1:93,448,118...93,554,661
|
|
G |
FNDC3B |
fibronectin type III domain containing 3B |
increases expression |
EXP |
Thapsigargin results in increased expression of FNDC3B mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 3:172,039,578...172,401,669
Ensembl chr 3:172,039,578...172,401,669
|
|
G |
FOS |
Fos proto-oncogene, AP-1 transcription factor subunit |
increases expression |
EXP |
Thapsigargin results in increased expression of FOS mRNA |
CTD |
PMID:21694771 PMID:29453283 |
|
NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,283,190
|
|
G |
FOSB |
FosB proto-oncogene, AP-1 transcription factor subunit |
increases expression |
EXP |
Thapsigargin results in increased expression of FOSB mRNA |
CTD |
PMID:21694771 PMID:29453283 |
|
NCBI chr19:45,467,996...45,475,179
Ensembl chr19:45,467,995...45,475,179
|
|
G |
FOXD2 |
forkhead box D2 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of FOXD2 mRNA |
CTD |
PMID:29453283 |
|
NCBI chr 1:47,438,044...47,440,691
Ensembl chr 1:47,438,044...47,440,691
|
|
G |
FOXO4 |
forkhead box O4 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of FOXO4 mRNA |
CTD |
PMID:29453283 |
|
NCBI chr X:71,095,851...71,103,532
Ensembl chr X:71,095,851...71,103,535
|
|
G |
FUBP1 |
far upstream element binding protein 1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of FUBP1 protein |
CTD |
PMID:35544339 |
|
NCBI chr 1:77,944,055...77,979,501
Ensembl chr 1:77,944,055...77,979,110
|
|
G |
FUNDC2 |
FUN14 domain containing 2 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of FUNDC2 protein |
CTD |
PMID:24648495 |
|
NCBI chr X:155,026,844...155,060,304
Ensembl chr X:155,025,980...155,060,304
|
|
G |
FYB1 |
FYN binding protein 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of FYB1 protein |
CTD |
PMID:35544339 |
|
NCBI chr 5:39,105,252...39,274,528
Ensembl chr 5:39,105,252...39,274,528
|
|
G |
FZD7 |
frizzled class receptor 7 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of FZD7 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 2:202,033,855...202,038,441
Ensembl chr 2:202,033,855...202,038,441
|
|
G |
G3BP1 |
G3BP stress granule assembly factor 1 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of G3BP1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 5:151,771,954...151,812,785
Ensembl chr 5:151,771,045...151,812,911
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|
G |
G6PD |
glucose-6-phosphate dehydrogenase |
increases expression |
ISO |
Thapsigargin results in increased expression of G6PD protein |
CTD |
PMID:35544339 |
|
NCBI chr X:154,531,390...154,547,569
Ensembl chr X:154,517,825...154,547,572
|
|
G |
GABBR1 |
gamma-aminobutyric acid type B receptor subunit 1 |
affects localization |
ISO |
Thapsigargin affects the localization of GABBR1 protein |
CTD |
PMID:24668805 |
|
NCBI chr 6:29,602,238...29,633,183
Ensembl chr 6:29,555,629...29,633,976
|
|
G |
GABBR2 |
gamma-aminobutyric acid type B receptor subunit 2 |
affects localization |
ISO |
Thapsigargin affects the localization of GABBR2 protein |
CTD |
PMID:24668805 |
|
NCBI chr 9:98,288,109...98,708,935
Ensembl chr 9:98,288,109...98,708,935
|
|
G |
GADD45A |
growth arrest and DNA damage inducible alpha |
increases expression |
EXP |
Thapsigargin results in increased expression of GADD45A mRNA |
CTD |
PMID:17332266 PMID:29453283 PMID:33770205 |
|
NCBI chr 1:67,685,201...67,688,334
Ensembl chr 1:67,685,201...67,688,334
|
|
G |
GADD45B |
growth arrest and DNA damage inducible beta |
increases expression |
EXP |
Thapsigargin results in increased expression of GADD45B mRNA |
CTD |
PMID:29453283 |
|
NCBI chr19:2,476,127...2,478,257
Ensembl chr19:2,476,122...2,478,805
|
|
G |
GADD45G |
growth arrest and DNA damage inducible gamma |
increases expression |
EXP |
Thapsigargin results in increased expression of GADD45G mRNA |
CTD |
PMID:29453283 |
|
NCBI chr 9:89,605,012...89,606,555
Ensembl chr 9:89,605,012...89,606,555
|
|
G |
GAL |
galanin and GMAP prepropeptide |
decreases expression |
EXP |
Thapsigargin results in decreased expression of GAL mRNA |
CTD |
PMID:22378314 |
|
NCBI chr11:68,684,544...68,691,175
Ensembl chr11:68,683,779...68,691,175
|
|
G |
GALK2 |
galactokinase 2 |
increases expression |
EXP |
Thapsigargin results in increased expression of GALK2 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr15:49,155,774...49,367,740
Ensembl chr15:49,155,656...49,367,869
|
|
G |
GALNT7 |
polypeptide N-acetylgalactosaminyltransferase 7 |
increases expression |
ISO |
Thapsigargin results in increased expression of GALNT7 protein |
CTD |
PMID:35544339 |
|
NCBI chr 4:173,168,811...173,323,967
Ensembl chr 4:173,168,811...173,323,967
|
|
G |
GALR2 |
galanin receptor 2 |
increases expression |
EXP |
Thapsigargin results in increased expression of GALR2 mRNA |
CTD |
PMID:29453283 |
|
NCBI chr17:76,071,962...76,077,537
Ensembl chr17:76,074,781...76,077,537
|
|
G |
GANAB |
glucosidase II alpha subunit |
increases expression |
EXP ISO |
Thapsigargin results in increased expression of GANAB mRNA Thapsigargin results in increased expression of GANAB protein |
CTD |
PMID:22378314 PMID:24648495 |
|
NCBI chr11:62,624,829...62,646,613
Ensembl chr11:62,624,826...62,646,726
|
|
G |
GAP43 |
growth associated protein 43 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of GAP43 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 3:115,623,510...115,721,483
Ensembl chr 3:115,623,510...115,721,490
|
|
G |
GAPDH |
glyceraldehyde-3-phosphate dehydrogenase |
increases expression |
ISO |
Thapsigargin results in increased expression of GAPDH protein |
CTD |
PMID:35544339 |
|
NCBI chr12:6,534,517...6,538,371
Ensembl chr12:6,534,512...6,538,374
|
|
G |
GARS1 |
glycyl-tRNA synthetase 1 |
increases expression |
EXP ISO |
Thapsigargin results in increased expression of GARS1 mRNA; Thapsigargin results in increased expression of GARS1 protein |
CTD |
PMID:22378314 PMID:29453283 PMID:35544339 |
|
NCBI chr 7:30,594,735...30,634,033
Ensembl chr 7:30,580,533...30,634,033
|
|
G |
GAS1 |
growth arrest specific 1 |
decreases expression increases expression |
ISO EXP |
Thapsigargin results in decreased expression of GAS1 protein Thapsigargin results in increased expression of GAS1 mRNA |
CTD |
PMID:24648495 PMID:29453283 |
|
NCBI chr 9:86,944,362...86,947,506
Ensembl chr 9:86,944,362...86,947,506
|
|
G |
GATA2 |
GATA binding protein 2 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of GATA2 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 3:128,479,422...128,493,201
Ensembl chr 3:128,479,427...128,493,201
|
|
G |
GC |
GC vitamin D binding protein |
increases expression |
ISO |
Thapsigargin results in increased expression of GC protein |
CTD |
PMID:35544339 |
|
NCBI chr 4:71,741,693...71,805,520
Ensembl chr 4:71,741,696...71,804,041
|
|
G |
GCAT |
glycine C-acetyltransferase |
decreases expression |
EXP |
Thapsigargin results in decreased expression of GCAT mRNA |
CTD |
PMID:22378314 |
|
NCBI chr22:37,807,934...37,817,183
Ensembl chr22:37,807,905...37,817,176
|
|
G |
GCDH |
glutaryl-CoA dehydrogenase |
decreases expression |
EXP |
Thapsigargin results in decreased expression of GCDH mRNA |
CTD |
PMID:22378314 |
|
NCBI chr19:12,891,129...12,899,999
Ensembl chr19:12,891,128...12,915,126
|
|
G |
GCK |
glucokinase |
increases expression |
ISO |
Thapsigargin results in increased expression of GCK protein |
CTD |
PMID:35544339 |
|
NCBI chr 7:44,143,213...44,189,439
Ensembl chr 7:44,143,213...44,198,170
|
|
G |
GCLC |
glutamate-cysteine ligase catalytic subunit |
increases expression |
ISO |
Thapsigargin results in increased expression of GCLC protein |
CTD |
PMID:35544339 |
|
NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970
|
|
G |
GCNA |
germ cell nuclear acidic peptidase |
increases expression |
EXP |
Thapsigargin results in increased expression of GCNA mRNA |
CTD |
PMID:29453283 |
|
NCBI chr X:71,578,437...71,613,583
Ensembl chr X:71,578,437...71,613,583
|
|
G |
GDE1 |
glycerophosphodiester phosphodiesterase 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of GDE1 protein |
CTD |
PMID:35544339 |
|
NCBI chr16:19,501,693...19,522,098
Ensembl chr16:19,501,693...19,522,123
|
|
G |
GDF15 |
growth differentiation factor 15 |
increases expression |
EXP |
Thapsigargin results in increased expression of GDF15 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr19:18,386,158...18,389,176
Ensembl chr19:18,374,731...18,389,176
|
|
G |
GDI1 |
GDP dissociation inhibitor 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of GDI1 protein |
CTD |
PMID:35544339 |
|
NCBI chr X:154,437,154...154,443,467
Ensembl chr X:154,436,913...154,443,467
|
|
G |
GDI2 |
GDP dissociation inhibitor 2 |
increases expression |
ISO |
Thapsigargin results in increased expression of GDI2 protein |
CTD |
PMID:35544339 |
|
NCBI chr10:5,765,223...5,813,434
Ensembl chr10:5,765,222...5,842,132
|
|
G |
GEM |
GTP binding protein overexpressed in skeletal muscle |
increases expression |
EXP |
Thapsigargin results in increased expression of GEM mRNA |
CTD |
PMID:21694771 PMID:29453283 |
|
NCBI chr 8:94,249,253...94,262,319
Ensembl chr 8:94,249,253...94,262,350
|
|
G |
GEMIN4 |
gem nuclear organelle associated protein 4 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of GEMIN4 mRNA |
CTD |
PMID:24247028 |
|
NCBI chr17:744,421...754,410
Ensembl chr17:744,421...753,999
|
|
G |
GEMIN5 |
gem nuclear organelle associated protein 5 |
increases expression |
ISO |
Thapsigargin results in increased expression of GEMIN5 protein |
CTD |
PMID:24648495 |
|
NCBI chr 5:154,887,411...154,938,211
Ensembl chr 5:154,887,411...154,938,211
|
|
G |
GET3 |
guided entry of tail-anchored proteins factor 3, ATPase |
increases expression |
ISO |
Thapsigargin results in increased expression of GET3 protein |
CTD |
PMID:35544339 |
|
NCBI chr19:12,737,106...12,748,323
Ensembl chr19:12,737,139...12,748,323
|
|
G |
GFM1 |
G elongation factor mitochondrial 1 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of GFM1 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr 3:158,644,527...158,695,581
Ensembl chr 3:158,644,527...158,695,581
|
|
G |
GFPT1 |
glutamine--fructose-6-phosphate transaminase 1 |
increases expression |
EXP ISO |
Thapsigargin results in increased expression of GFPT1 mRNA Thapsigargin results in increased expression of GFPT1 protein |
CTD |
PMID:22378314 PMID:29453283 PMID:35544339 |
|
NCBI chr 2:69,319,780...69,387,227
Ensembl chr 2:69,319,780...69,387,250
|
|
G |
GGCT |
gamma-glutamylcyclotransferase |
decreases expression |
ISO |
Thapsigargin results in decreased expression of GGCT protein |
CTD |
PMID:24648495 |
|
NCBI chr 7:30,496,621...30,504,829
Ensembl chr 7:30,496,621...30,504,841
|
|
G |
GGT7 |
gamma-glutamyltransferase 7 |
increases expression |
ISO |
Thapsigargin results in increased expression of GGT7 protein |
CTD |
PMID:35544339 |
|
NCBI chr20:34,844,720...34,872,856
Ensembl chr20:34,844,720...34,872,856
|
|
G |
GINS2 |
GINS complex subunit 2 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of GINS2 mRNA |
CTD |
PMID:22378314 |
|
NCBI chr16:85,676,198...85,688,954
Ensembl chr16:85,676,198...85,690,073
|
|
G |
GIPC2 |
GIPC PDZ domain containing family member 2 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of GIPC2 protein |
CTD |
PMID:35544339 |
|
NCBI chr 1:78,044,970...78,138,444
Ensembl chr 1:77,979,542...78,138,444
|
|
G |
GLA |
galactosidase alpha |
increases expression |
EXP |
Thapsigargin results in increased expression of GLA mRNA |
CTD |
PMID:29453283 |
|
NCBI chr X:101,397,803...101,407,925
Ensembl chr X:101,393,273...101,408,012
|
|
G |
GLDC |
glycine decarboxylase |
decreases expression increases expression |
EXP |
Thapsigargin results in decreased expression of GLDC mRNA Thapsigargin results in increased expression of GLDC mRNA |
CTD |
PMID:22378314 PMID:33770205 |
|
NCBI chr 9:6,532,467...6,645,729
Ensembl chr 9:6,532,467...6,645,729
|
|
G |
GLG1 |
golgi glycoprotein 1 |
increases expression decreases expression |
ISO |
Thapsigargin results in increased expression of GLG1 protein Thapsigargin results in decreased expression of GLG1 protein |
CTD |
PMID:24648495 PMID:35544339 |
|
NCBI chr16:74,447,440...74,607,114
Ensembl chr16:74,447,427...74,607,144
|
|
G |
GLO1 |
glyoxalase I |
decreases expression |
ISO |
Thapsigargin results in decreased expression of GLO1 protein |
CTD |
PMID:24648495 |
|
NCBI chr 6:38,675,925...38,703,145
Ensembl chr 6:38,675,925...38,703,145
|
|
G |
GLRX3 |
glutaredoxin 3 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of GLRX3 protein |
CTD |
PMID:24648495 |
|
NCBI chr10:130,136,391...130,180,377
Ensembl chr10:130,136,391...130,184,521
|
|
G |
GLS |
glutaminase |
increases expression decreases expression |
EXP ISO |
Thapsigargin results in increased expression of GLS mRNA Thapsigargin results in decreased expression of GLS protein |
CTD |
PMID:22378314 PMID:29453283 PMID:35544339 |
|
NCBI chr 2:190,880,821...190,965,552
Ensembl chr 2:190,880,821...190,965,552
|
|
G |
GLUL |
glutamate-ammonia ligase |
decreases expression |
ISO |
Thapsigargin results in decreased expression of GLUL protein |
CTD |
PMID:35544339 |
|
NCBI chr 1:182,378,098...182,391,790
Ensembl chr 1:182,378,098...182,392,206
|
|
G |
GLYR1 |
glyoxylate reductase 1 homolog |
decreases expression |
ISO |
Thapsigargin results in decreased expression of GLYR1 protein |
CTD |
PMID:35544339 |
|
NCBI chr16:4,803,203...4,847,288
Ensembl chr16:4,803,203...4,847,288
|
|
G |
GMEB1 |
glucocorticoid modulatory element binding protein 1 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of GMEB1 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 1:28,668,229...28,719,353
Ensembl chr 1:28,668,778...28,719,353
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G |
GMNN |
geminin DNA replication inhibitor |
decreases expression |
EXP |
Thapsigargin results in decreased expression of GMNN mRNA |
CTD |
PMID:22378314 |
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NCBI chr 6:24,774,937...24,786,099
Ensembl chr 6:24,774,931...24,786,099
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G |
GMPPA |
GDP-mannose pyrophosphorylase A |
increases expression |
EXP |
Thapsigargin results in increased expression of GMPPA mRNA |
CTD |
PMID:22378314 |
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NCBI chr 2:219,498,891...219,506,989
Ensembl chr 2:219,498,865...219,513,898
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G |
GNAI3 |
G protein subunit alpha i3 |
increases expression |
ISO |
Thapsigargin results in increased expression of GNAI3 protein |
CTD |
PMID:35544339 |
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NCBI chr 1:109,548,615...109,600,195
Ensembl chr 1:109,548,615...109,600,195
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G |
GNAO1 |
G protein subunit alpha o1 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of GNAO1 protein |
CTD |
PMID:35544339 |
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NCBI chr16:56,191,489...56,357,444
Ensembl chr16:56,189,660...56,357,444
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G |
GNAS |
GNAS complex locus |
increases expression |
ISO |
Thapsigargin results in increased expression of GNAS protein |
CTD |
PMID:35544339 |
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NCBI chr20:58,839,748...58,911,192
Ensembl chr20:58,839,718...58,911,192
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G |
GNB1 |
G protein subunit beta 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of GNB1 protein |
CTD |
PMID:35544339 |
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NCBI chr 1:1,785,286...1,891,087
Ensembl chr 1:1,785,285...1,892,292
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G |
GNG12 |
G protein subunit gamma 12 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of GNG12 mRNA |
CTD |
PMID:29453283 |
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NCBI chr 1:67,701,475...67,833,467
Ensembl chr 1:67,701,475...67,833,467
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G |
GNG2 |
G protein subunit gamma 2 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of GNG2 mRNA |
CTD |
PMID:22378314 |
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NCBI chr14:51,826,174...51,969,795
Ensembl chr14:51,826,195...51,979,342
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G |
GNL3L |
G protein nucleolar 3 like |
increases expression |
EXP |
Thapsigargin results in increased expression of GNL3L mRNA |
CTD |
PMID:22378314 |
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NCBI chr X:54,530,219...54,645,854
Ensembl chr X:54,530,183...54,621,521
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G |
GOLGA2 |
golgin A2 |
increases expression |
EXP |
Thapsigargin results in increased expression of GOLGA2 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 9:128,255,829...128,276,007
Ensembl chr 9:128,255,829...128,276,026
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G |
GOLGA3 |
golgin A3 |
increases expression |
EXP |
Thapsigargin results in increased expression of GOLGA3 mRNA |
CTD |
PMID:22378314 |
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NCBI chr12:132,768,914...132,829,081
Ensembl chr12:132,768,902...132,829,143
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G |
GOLGA5 |
golgin A5 |
increases expression decreases expression |
EXP ISO |
Thapsigargin results in increased expression of GOLGA5 mRNA Thapsigargin results in decreased expression of GOLGA5 protein |
CTD |
PMID:22378314 PMID:35544339 |
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NCBI chr14:92,794,305...92,839,947
Ensembl chr14:92,794,305...92,839,947
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G |
GOLIM4 |
golgi integral membrane protein 4 |
decreases expression |
ISO |
Thapsigargin results in decreased expression of GOLIM4 protein |
CTD |
PMID:35544339 |
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NCBI chr 3:168,008,689...168,095,924
Ensembl chr 3:168,008,689...168,095,924
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G |
GOSR1 |
golgi SNAP receptor complex member 1 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of GOSR1 mRNA |
CTD |
PMID:19442820 |
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NCBI chr17:30,477,408...30,527,592
Ensembl chr17:30,477,362...30,527,592
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G |
GOT2 |
glutamic-oxaloacetic transaminase 2 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of GOT2 mRNA |
CTD |
PMID:22378314 |
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NCBI chr16:58,707,131...58,734,316
Ensembl chr16:58,707,131...58,734,342
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G |
GPD1 |
glycerol-3-phosphate dehydrogenase 1 |
increases expression |
ISO |
Thapsigargin results in increased expression of GPD1 protein |
CTD |
PMID:35544339 |
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NCBI chr12:50,104,008...50,111,313
Ensembl chr12:50,103,982...50,111,313
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G |
GPD2 |
glycerol-3-phosphate dehydrogenase 2 |
increases expression decreases expression |
ISO |
Thapsigargin results in increased expression of GPD2 protein Thapsigargin results in decreased expression of GPD2 protein |
CTD |
PMID:24648495 PMID:35544339 |
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NCBI chr 2:156,400,281...156,586,403
Ensembl chr 2:156,435,290...156,613,735
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G |
GPI |
glucose-6-phosphate isomerase |
increases expression |
ISO |
Thapsigargin results in increased expression of GPI protein |
CTD |
PMID:35544339 |
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NCBI chr19:34,359,718...34,402,413
Ensembl chr19:34,359,480...34,402,413
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G |
GPR137B |
G protein-coupled receptor 137B |
decreases expression |
EXP |
Thapsigargin results in decreased expression of GPR137B mRNA |
CTD |
PMID:29453283 |
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NCBI chr 1:236,142,539...236,208,907
Ensembl chr 1:236,142,505...236,221,865
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G |
GPR22 |
G protein-coupled receptor 22 |
increases expression |
EXP |
Thapsigargin results in increased expression of GPR22 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 7:107,470,057...107,477,845
Ensembl chr 7:107,470,018...107,475,684
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G |
GPRC5B |
G protein-coupled receptor class C group 5 member B |
decreases expression |
ISO |
Thapsigargin results in decreased expression of GPRC5B protein |
CTD |
PMID:24648495 |
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NCBI chr16:19,856,691...19,885,634
Ensembl chr16:19,856,691...19,886,167
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G |
GPS2 |
G protein pathway suppressor 2 |
increases expression |
EXP |
Thapsigargin results in increased expression of GPS2 mRNA |
CTD |
PMID:22378314 |
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NCBI chr17:7,312,661...7,315,360
Ensembl chr17:7,311,324...7,315,564
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G |
GPSM2 |
G protein signaling modulator 2 |
decreases expression |
EXP |
Thapsigargin results in decreased expression of GPSM2 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 1:108,876,985...108,934,545
Ensembl chr 1:108,875,350...108,934,545
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G |
GPT2 |
glutamic--pyruvic transaminase 2 |
increases expression |
EXP |
Thapsigargin results in increased expression of GPT2 mRNA |
CTD |
PMID:22378314 PMID:29453283 |
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NCBI chr16:46,884,362...46,931,289
Ensembl chr16:46,884,362...46,931,289
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G |
GPX4 |
glutathione peroxidase 4 |
increases expression |
ISO |
Thapsigargin results in increased expression of GPX4 protein |
CTD |
PMID:35544339 |
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NCBI chr19:1,103,994...1,106,779
Ensembl chr19:1,103,982...1,106,791
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G |
GPX8 |
glutathione peroxidase 8 (putative) |
increases expression |
EXP |
Thapsigargin results in increased expression of GPX8 mRNA |
CTD |
PMID:29453283 |
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NCBI chr 5:55,160,171...55,167,297
Ensembl chr 5:55,160,167...55,167,297
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G |
GRPEL1 |
GrpE like 1, mitochondrial |
decreases expression |
EXP ISO |
Thapsigargin results in decreased expression of GRPEL1 mRNA Thapsigargin results in decreased expression of GRPEL1 protein |
CTD |
PMID:22378314 PMID:35544339 |
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NCBI chr 4:7,058,895...7,068,064
Ensembl chr 4:7,058,671...7,068,085
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G |
GRPEL2 |
GrpE like 2, mitochondrial |
increases expression |
EXP |
Thapsigargin results in increased expression of GRPEL2 mRNA |
CTD |
PMID:22378314 |
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NCBI chr 5:149,345,499...149,354,583
Ensembl chr 5:149,345,430...149,354,583
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G |
GSDMB |
gasdermin B |
increases expression |
EXP |
Thapsigargin results in increased expression of GSDMB mRNA |
CTD |
PMID:22378314 |
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NCBI chr17:39,904,595...39,918,635
Ensembl chr17:39,904,595...39,919,854
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G |
GSDMD |
gasdermin D |
increases expression |
EXP |
Thapsigargin results in increased expression of GSDMD mRNA |
CTD |
PMID:30796460 |
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NCBI chr 8:143,553,387...143,563,062
Ensembl chr 8:143,553,207...143,563,062
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G |
GSN |
gelsolin |
increases expression |
ISO |
Thapsigargin results in increased expression of GSN protein |
CTD |
PMID:35544339 |
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NCBI chr 9:121,201,483...121,332,842
Ensembl chr 9:121,207,794...121,332,843
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G |
GSR |
glutathione-disulfide reductase |
multiple interactions decreases expression |
EXP |
4-methoxycinnamate methyl ester promotes the reaction [Thapsigargin results in decreased expression of GSR mRNA]; caffeic acid promotes the reaction [Thapsigargin results in decreased expression of GSR mRNA]; Drugs, Chinese Herbal promotes the reaction [Thapsigargin results in decreased expression of GSR mRNA] |
CTD |
PMID:19442820 |
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NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
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G |
GTF2I |
general transcription factor IIi |
decreases expression |
ISO |
Thapsigargin results in decreased expression of GTF2I protein |
CTD |
PMID:35544339 |
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NCBI chr 7:74,657,718...74,760,692
Ensembl chr 7:74,650,231...74,760,692
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G |
H1-0 |
H1.0 linker histone |
decreases expression |
ISO |
Thapsigargin results in decreased expression of H1F0 protein |
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