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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Testosterone propionate
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Accession:CHEBI:9466 term browser browse the term
Definition:A steroid ester that has formula C22H32O3.
Synonyms:related_synonym: Formula=C22H32O3;   InChI=1S/C22H32O3/c1-4-20(24)25-19-8-7-17-16-6-5-14-13-15(23)9-11-21(14,2)18(16)10-12-22(17,19)3/h13,16-19H,4-12H2,1-3H3/t16-,17-,18-,19-,21-,22-/m0/s1;   InChIKey=PDMMFKSKQVNJMI-BLQWBTBKSA-N;   SMILES=CCC(=O)O[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C;   TP;   virormone
 xref: CAS:57-85-2;   Drug_Central:4146;   HMDB:HMDB0015489;   KEGG:C08158;   KEGG:D00959
 xref_mesh: MESH:D043343



show annotations for term's descendants           Sort by:
Testosterone propionate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr2b activin A receptor type 2B multiple interactions
increases expression
EXP Flutamide inhibits the reaction [Testosterone Propionate results in increased expression of SCGB2A2 mRNA]; prochloraz inhibits the reaction [Testosterone Propionate results in increased expression of SCGB2A2 mRNA]; vinclozolin inhibits the reaction [Testosterone Propionate results in increased expression of SCGB2A2 mRNA] CTD PMID:11376863 PMID:12377983 NCBI chr 8:119,138,901...119,178,477
Ensembl chr 8:119,138,812...119,170,458
JBrowse link
G Adcyap1 adenylate cyclase activating polypeptide 1 increases expression EXP Testosterone Propionate results in increased expression of ADCYAP1 mRNA CTD PMID:19427307 NCBI chr 9:113,102,632...113,122,500
Ensembl chr 9:113,103,718...113,109,773
JBrowse link
G Adgrg2 adhesion G protein-coupled receptor G2 increases expression ISO Testosterone Propionate results in increased expression of ADGRG2 mRNA CTD PMID:15601916 NCBI chr  X:34,297,402...34,422,590
Ensembl chr  X:34,297,402...34,422,609
JBrowse link
G Adprhl1 ADP-ribosylhydrolase like 1 decreases expression ISO Testosterone Propionate results in decreased expression of ADPRHL1 mRNA CTD PMID:15601916 NCBI chr16:76,283,186...76,315,075
Ensembl chr16:76,283,103...76,354,440
JBrowse link
G Agt angiotensinogen increases expression EXP Testosterone Propionate results in increased expression of AGT mRNA CTD PMID:1568764 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Amotl1 angiomotin-like 1 increases expression ISO Testosterone Propionate results in increased expression of AMOTL1 mRNA CTD PMID:15601916 NCBI chr 8:11,348,651...11,467,564
Ensembl chr 8:11,353,674...11,467,573
JBrowse link
G Ar androgen receptor affects binding
increases expression
multiple interactions
EXP
ISO
Testosterone Propionate binds to AR protein
Testosterone Propionate results in increased expression of AR protein
Testosterone Propionate inhibits the reaction [Endosulfan results in decreased expression of AR mRNA]
Testosterone Propionate inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]
Diosmin inhibits the reaction [Testosterone Propionate results in increased expression of AR protein]
CTD PMID:14565775 PMID:23669243 PMID:25077688 PMID:31797688 PMID:33049310 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Atp6v0d2 ATPase H+ transporting V0 subunit D2 increases expression ISO Testosterone Propionate results in increased expression of ATP6V0D2 mRNA CTD PMID:15601916 NCBI chr 5:33,336,257...33,385,354
Ensembl chr 5:33,336,264...33,385,354
JBrowse link
G Bdnf brain-derived neurotrophic factor increases expression EXP Testosterone Propionate results in increased expression of BDNF mRNA CTD PMID:19427307 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A increases expression ISO Testosterone Propionate results in increased expression of CACNA1A mRNA CTD PMID:15601916 NCBI chr19:23,520,741...23,819,971
Ensembl chr19:23,520,741...23,823,225
JBrowse link
G Cat catalase decreases expression
multiple interactions
decreases activity
EXP Testosterone Propionate results in decreased expression of CAT protein
Diosmin inhibits the reaction [Testosterone Propionate results in decreased activity of CAT protein]; Testosterone Propionate inhibits the reaction [Vanadium results in decreased activity of CAT protein]
CTD PMID:9430440 PMID:20521886 PMID:31797688 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Clu clusterin multiple interactions
decreases expression
EXP Flutamide inhibits the reaction [Testosterone Propionate results in decreased expression of CLU mRNA]; vinclozolin inhibits the reaction [Testosterone Propionate results in decreased expression of CLU mRNA] CTD PMID:11376863 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Cr1l complement C3b/C4b receptor 1 like multiple interactions ISO Testosterone Propionate inhibits the reaction [Endosulfan results in decreased expression of CR1L mRNA] CTD PMID:25242399 NCBI chr13:106,606,952...106,660,442
Ensembl chr13:106,574,858...106,660,445
JBrowse link
G Creg2 cellular repressor of E1A-stimulated genes 2 decreases expression ISO Testosterone Propionate results in decreased expression of CREG2 mRNA CTD PMID:15601916 NCBI chr 9:41,872,000...41,945,413
Ensembl chr 9:41,902,304...41,945,095
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression ISO Testosterone Propionate results in decreased expression of CYP17A1 mRNA CTD PMID:15601916 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 affects expression ISO Testosterone Propionate affects the expression of CYP2A4 CTD PMID:20943812 NCBI chr 1:82,171,914...82,179,980
Ensembl chr 1:82,169,949...82,179,979
JBrowse link
G Dhx9 DExH-box helicase 9 decreases expression ISO Testosterone Propionate results in decreased expression of DHX9 mRNA CTD PMID:15601916 NCBI chr13:65,602,322...65,639,098
Ensembl chr13:65,602,323...65,639,069
JBrowse link
G Dnai1 dynein, axonemal, intermediate chain 1 increases expression ISO Testosterone Propionate results in increased expression of DNAI1 mRNA CTD PMID:15601916 NCBI chr 5:56,730,179...56,800,926
Ensembl chr 5:56,730,179...56,800,925
JBrowse link
G Epha2 Eph receptor A2 decreases expression ISO Testosterone Propionate results in decreased expression of EPHA2 mRNA CTD PMID:15601916 NCBI chr 5:153,605,644...153,634,115
Ensembl chr 5:153,605,644...153,634,117
JBrowse link
G Esr1 estrogen receptor 1 decreases expression
multiple interactions
EXP
ISO
Testosterone Propionate results in decreased expression of ESR1 protein
Testosterone Propionate binds to and results in increased activity of ESR1 protein
CTD PMID:23669243 PMID:33049310 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO Testosterone Propionate binds to and results in decreased activity of ESR2 protein CTD PMID:33049310 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions EXP Testosterone Propionate inhibits the reaction [Cyclosporine results in increased expression of FSHB protein] CTD PMID:2128298 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370
JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 decreases expression ISO Testosterone Propionate results in decreased expression of GABRA1 mRNA CTD PMID:16957604 NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864
JBrowse link
G Gabra2 gamma-aminobutyric acid type A receptor subunit alpha 2 decreases expression ISO Testosterone Propionate results in decreased expression of GABRA2 mRNA CTD PMID:16957604 NCBI chr14:37,097,251...37,230,030
Ensembl chr14:37,097,279...37,228,944
JBrowse link
G Gabra4 gamma-aminobutyric acid type A receptor subunit alpha 4 increases expression ISO Testosterone Propionate results in increased expression of GABRA4 mRNA CTD PMID:16957604 NCBI chr14:36,590,782...36,667,724
Ensembl chr14:36,590,782...36,665,844
JBrowse link
G Gabra5 gamma-aminobutyric acid type A receptor subunit alpha 5 increases expression ISO Testosterone Propionate results in increased expression of GABRA5 mRNA CTD PMID:16957604 NCBI chr 1:108,268,728...108,381,670
Ensembl chr 1:108,268,776...108,380,917
JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 decreases expression ISO Testosterone Propionate results in decreased expression of GABRG2 mRNA CTD PMID:16957604 NCBI chr10:26,374,693...26,463,937
Ensembl chr10:26,374,694...26,464,346
JBrowse link
G Gap43 growth associated protein 43 increases expression EXP Testosterone Propionate results in increased expression of GAP43 mRNA CTD PMID:19427307 NCBI chr11:58,376,371...58,470,047
Ensembl chr11:58,376,371...58,470,045
JBrowse link
G Ghrh growth hormone releasing hormone affects expression ISO Testosterone Propionate affects the expression of GHRH mRNA CTD PMID:20943812 NCBI chr 3:145,992,762...146,012,528
Ensembl chr 3:145,992,763...146,011,889
JBrowse link
G Gmppb GDP-mannose pyrophosphorylase B decreases expression ISO Testosterone Propionate results in decreased expression of GMPPB mRNA CTD PMID:15601916 NCBI chr 8:108,737,429...108,740,437
Ensembl chr 8:108,693,060...108,767,286
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions
decreases activity
EXP Diosmin inhibits the reaction [Testosterone Propionate results in decreased activity of GSR protein] CTD PMID:31797688 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO Testosterone Propionate inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G H3c1 H3 clustered histone 1 decreases expression ISO Testosterone Propionate results in decreased expression of H3C1 mRNA CTD PMID:15601916 NCBI chr17:41,368,379...41,368,902
Ensembl chr17:41,368,386...41,368,856
Ensembl chr17:41,368,386...41,368,856
Ensembl chr17:41,368,386...41,368,856
Ensembl chr17:41,368,386...41,368,856
JBrowse link
G Hspbap1 HSPB1 associated protein 1 decreases expression ISO Testosterone Propionate results in decreased expression of HSPBAP1 mRNA CTD PMID:15601916 NCBI chr11:64,940,089...64,994,753
Ensembl chr11:64,940,091...64,994,756
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO Testosterone Propionate promotes the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of IL1B mRNA] CTD PMID:21745355 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
ISO
EXP
Testosterone Propionate inhibits the reaction [Endosulfan results in increased expression of IL6 mRNA]; Testosterone Propionate promotes the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of IL6 mRNA]
Diosmin inhibits the reaction [Testosterone Propionate results in increased expression of IL6 protein]
CTD PMID:21745355 PMID:22591281 PMID:31797688 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Klk1c10 kallikrein 1-related peptidase C10 multiple interactions
increases expression
EXP Diosmin inhibits the reaction [Testosterone Propionate results in increased expression of KLK3 protein] CTD PMID:31797688 NCBI chr 1:94,402,993...94,407,052
Ensembl chr 1:94,402,993...94,407,052
JBrowse link
G Lhb luteinizing hormone subunit beta decreases expression
multiple interactions
EXP
ISO
Testosterone Propionate results in decreased expression of LHB protein
Flutamide inhibits the reaction [Testosterone Propionate results in decreased expression of LHB protein]
Testosterone Propionate inhibits the reaction [Endosulfan results in increased expression of LHB]
CTD PMID:2128298 PMID:11376863 PMID:25077688 NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972
JBrowse link
G Mir204 microRNA 204 decreases expression EXP Testosterone Propionate results in decreased expression of MIR204 mRNA CTD PMID:25797256 NCBI chr 1:220,316,931...220,317,040
Ensembl chr 1:220,316,931...220,317,040
JBrowse link
G Mpv17 mitochondrial inner membrane protein MPV17 increases expression ISO Testosterone Propionate results in increased expression of MPV17 mRNA CTD PMID:15601916 NCBI chr 6:25,221,668...25,236,241
Ensembl chr 6:25,222,896...25,236,244
JBrowse link
G Mrpl54 mitochondrial ribosomal protein L54 increases expression ISO Testosterone Propionate results in increased expression of MRPL54 mRNA CTD PMID:15601916 NCBI chr 7:8,452,801...8,455,321
Ensembl chr 7:8,452,716...8,455,321
JBrowse link
G Mycn MYCN proto-oncogene, bHLH transcription factor decreases expression ISO Testosterone Propionate results in decreased expression of MYCN mRNA CTD PMID:15601916 NCBI chr 6:35,717,764...35,723,590
Ensembl chr 6:35,717,764...35,723,590
JBrowse link
G Nphp1 nephrocystin 1 decreases expression ISO Testosterone Propionate results in decreased expression of NPHP1 mRNA CTD PMID:15601916 NCBI chr 3:114,960,650...115,016,234
Ensembl chr 3:114,960,650...115,016,234
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression IEP Testosterone propionate increases NQO1 protein in liver RGD PMID:31819135 RGD:25823186 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO Testosterone Propionate binds to and results in increased activity of NR1I2 protein
Testosterone Propionate binds to and results in decreased activity of NR1I2 protein
CTD PMID:33049310 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Nrn1 neuritin 1 increases expression EXP Testosterone Propionate results in increased expression of NRN1 mRNA CTD PMID:19427307 NCBI chr17:28,129,969...28,138,898
Ensembl chr17:28,129,977...28,138,896
JBrowse link
G Odc1 ornithine decarboxylase 1 multiple interactions
increases expression
EXP Flutamide inhibits the reaction [Testosterone Propionate results in increased expression of ODC1 mRNA]; prochloraz inhibits the reaction [Testosterone Propionate results in increased expression of ODC1 mRNA] CTD PMID:12377983 PMID:17688994 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
JBrowse link
G Osbpl3 oxysterol binding protein-like 3 decreases expression ISO Testosterone Propionate results in decreased expression of OSBPL3 mRNA CTD PMID:15601916 NCBI chr 4:79,346,583...79,523,523
Ensembl chr 4:79,350,349...79,523,393
JBrowse link
G Pgr progesterone receptor decreases expression
increases expression
ISO
EXP
Testosterone Propionate results in decreased expression of PGR mRNA
Testosterone Propionate results in decreased expression of PGR protein
Testosterone Propionate results in increased expression of PGR protein
CTD PMID:17574608 PMID:23669243 NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link
G Plagl1 PLAG1 like zinc finger 1 decreases expression ISO Testosterone Propionate results in decreased expression of PLAGL1 mRNA CTD PMID:15601916 NCBI chr 1:7,477,295...7,517,229
Ensembl chr 1:7,477,177...7,517,228
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO Testosterone Propionate binds to and results in decreased activity of PPARG protein CTD PMID:33049310 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
EXP Diosmin inhibits the reaction [Testosterone Propionate results in increased expression of PTGS2 protein] CTD PMID:31797688 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ptpn23 protein tyrosine phosphatase, non-receptor type 23 decreases expression ISO Testosterone Propionate results in decreased expression of PTPN23 mRNA CTD PMID:15601916 NCBI chr 8:110,360,804...110,383,271
Ensembl chr 8:110,360,804...110,383,271
JBrowse link
G Recql RecQ like helicase decreases expression ISO Testosterone Propionate results in decreased expression of RECQL mRNA CTD PMID:15601916 NCBI chr 4:175,308,337...175,332,965
Ensembl chr 4:175,304,117...175,332,945
JBrowse link
G Ren renin increases expression EXP Testosterone Propionate results in increased expression of REN mRNA; Testosterone Propionate results in increased expression of REN protein CTD PMID:1568764 NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
JBrowse link
G Rnase9 ribonuclease A family member 9 increases expression EXP Testosterone Propionate results in increased expression of RNASE9 mRNA CTD PMID:17005942 NCBI chr15:24,259,525...24,263,079
Ensembl chr15:24,259,525...24,263,079
JBrowse link
G Slc12a1 solute carrier family 12 member 1 increases expression ISO Testosterone Propionate results in increased expression of SLC12A1 mRNA CTD PMID:15601916 NCBI chr 3:112,406,140...112,482,913
Ensembl chr 3:112,406,140...112,482,899
JBrowse link
G Slc9a2 solute carrier family 9 member A2 increases expression ISO Testosterone Propionate results in increased expression of SLC9A2 mRNA CTD PMID:15601916 NCBI chr 9:42,932,001...43,014,447
Ensembl chr 9:42,931,346...43,014,444
JBrowse link
G Syt6 synaptotagmin 6 increases expression ISO Testosterone Propionate results in increased expression of SYT6 mRNA CTD PMID:15601916 NCBI chr 2:191,093,009...191,152,283
Ensembl chr 2:191,093,007...191,149,956
JBrowse link
G Thrb thyroid hormone receptor beta multiple interactions ISO Testosterone Propionate binds to and results in increased activity of THRB protein CTD PMID:33049310 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO Testosterone Propionate promotes the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of TNF mRNA] CTD PMID:21745355 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tshz2 teashirt zinc finger homeobox 2 decreases expression ISO Testosterone Propionate results in decreased expression of TSHZ2 mRNA CTD PMID:15601916 NCBI chr 3:158,405,469...158,666,915
Ensembl chr 3:158,405,423...158,850,128
JBrowse link
G Tuba1a tubulin, alpha 1A increases expression EXP Testosterone Propionate results in increased expression of TUBA1A mRNA CTD PMID:19427307 NCBI chr 7:130,113,214...130,116,880
Ensembl chr 7:130,081,032...130,196,186
JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 decreases expression EXP Testosterone Propionate results in decreased expression of UGT2B1 mRNA CTD PMID:16829708 NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986
JBrowse link
G Ugt8 UDP glycosyltransferase 8 increases expression ISO Testosterone Propionate results in increased expression of UGT8A mRNA CTD PMID:15601916 NCBI chr 2:214,264,483...214,332,769
Ensembl chr 2:214,264,483...214,332,660
JBrowse link
G Xdh xanthine dehydrogenase increases activity
multiple interactions
EXP Testosterone Propionate results in increased activity of XDH protein
Diosmin inhibits the reaction [Testosterone Propionate results in increased activity of XDH protein]
CTD PMID:31797688 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268
JBrowse link
G Xrn1 5'-3' exoribonuclease 1 increases expression EXP Testosterone Propionate results in increased expression of XRN1 protein CTD PMID:25797256 NCBI chr 8:96,527,871...96,637,385
Ensembl chr 8:96,528,195...96,632,739
JBrowse link
G Zfp276 zinc finger protein (C2H2 type) 276 decreases expression ISO Testosterone Propionate results in decreased expression of ZFP276 mRNA CTD PMID:15601916 NCBI chr19:51,291,005...51,304,240
Ensembl chr19:51,290,777...51,304,049
JBrowse link

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  CHEBI ontology 19901
    chemical entity 19899
      atom 19899
        nonmetal atom 19822
          carbon atom 19775
            organic molecular entity 19775
              lipid 18001
                steroid 14731
                  steroid ester 1300
                    Testosterone propionate 68
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  CHEBI ontology 19901
    subatomic particle 19899
      composite particle 19899
        hadron 19899
          baryon 19899
            nucleon 19899
              atomic nucleus 19899
                atom 19899
                  main group element atom 19838
                    p-block element atom 19838
                      carbon group element atom 19778
                        carbon atom 19775
                          organic molecular entity 19775
                            organic molecule 19728
                              organic cyclic compound 19519
                                organic polycyclic compound 17313
                                  steroid 14731
                                    steroid ester 1300
                                      Testosterone propionate 68
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