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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2-ylidene)acetamide
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Accession:CHEBI:94513 term browser browse the term
Definition:A thiadiazole that has formula C5H8N4O3S2.
Synonyms:related_synonym: Formula=C5H8N4O3S2;   InChI=1S/C5H8N4O3S2/c1-3(10)7-4-9(2)8-5(13-4)14(6,11)12/h1-2H3,(H2,6,11,12);   InChIKey=FLOSMHQXBMRNHR-UHFFFAOYSA-N;   N-Methylacetazolamide;   SMILES=CC(=O)N=C1N(N=C(S1)S(=O)(=O)N)C;   metazolamide;   methenamide;   neptazane;   neptazaneat
 xref: CAS:554-57-4;   Drug_Central:1741;   LINCS:LSM-5311
 xref_mesh: MESH:D008704


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N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2-ylidene)acetamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Car1 carbonic anhydrase 1 multiple interactions ISO Methazolamide binds to and results in decreased activity of CA1 protein CTD PMID:17826101 NCBI chr 2:86,829,436...86,872,209
Ensembl chr 2:86,861,897...86,872,208 		JBrowse link
G Car2 carbonic anhydrase 2 multiple interactions
decreases activity		 ISO Methazolamide binds to and results in decreased activity of CA2 protein
Methazolamide results in decreased activity of CA2 protein		 CTD PMID:16858005 PMID:17826101 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818 		JBrowse link
G Car3 carbonic anhydrase 3 multiple interactions ISO Methazolamide binds to and results in decreased activity of CA3 protein CTD PMID:17826101 NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280 		JBrowse link
G Clu clusterin affects expression ISO Methazolamide affects the expression of CLU protein CTD PMID:12388792 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315 		JBrowse link
G Gal galanin and GMAP prepropeptide affects expression ISO Methazolamide affects the expression of GAL protein CTD PMID:12388792 NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959 		JBrowse link
G Gap43 growth associated protein 43 affects expression ISO Methazolamide affects the expression of GAP43 protein CTD PMID:12388792 NCBI chr11:58,376,371...58,470,047
Ensembl chr11:58,376,371...58,470,045 		JBrowse link
G Ret ret proto-oncogene affects expression ISO Methazolamide affects the expression of RET protein CTD PMID:12388792 NCBI chr 4:151,325,969...151,368,176
Ensembl chr 4:151,326,431...151,368,176 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 affects expression ISO Methazolamide affects the expression of TIMP1 protein CTD PMID:12388792 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19874
    chemical entity 19872
      atom 19872
        nonmetal atom 19794
          sulfur atom 17750
            sulfur molecular entity 17750
              organosulfur compound 17449
                sulfonamide 5307
                  N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2-ylidene)acetamide 8
Path 2
Term Annotations click to browse term
  CHEBI ontology 19874
    subatomic particle 19872
      composite particle 19872
        hadron 19872
          baryon 19872
            nucleon 19872
              atomic nucleus 19872
                atom 19872
                  main group element atom 19811
                    p-block element atom 19811
                      chalcogen 19563
                        oxygen atom 19535
                          oxygen molecular entity 19535
                            hydroxides 19341
                              oxoacid 18777
                                chalcogen oxoacid 13781
                                  sulfur oxoacid 13570
                                    sulfonic acid 11616
                                      sulfonic acid derivative 11616
                                        sulfonamide 5307
                                          N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2-ylidene)acetamide 8
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