CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: syringin
Accession: CHEBI:9380
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Definition: A monosaccharide derivative that is trans-sinapyl alcohol attached to a beta-D-glucopyranosyl residue at position 1 via a glycosidic linkage.
Synonyms: exact_synonym: 4-[(1E)-3-hydroxyprop-1-en-1-yl]-2,6-dimethoxyphenyl beta-D-glucopyranoside
related_synonym: (E)-sinapyl alcohol 4-glucoside; 4-O-(beta-D-glucosyl)-trans-4-sinapoyl alcohol; 4-[(1E)-3-hydroxy-1-propen-1-yl]-2,6-dimethoxyphenyl beta-D-glucopyranoside; Eleutheroside B; Formula=C17H24O9; InChI=1S/C17H24O9/c1-23-10-6-9(4-3-5-18)7-11(24-2)16(10)26-17-15(22)14(21)13(20)12(8-19)25-17/h3-4,6-7,12-15,17-22H,5,8H2,1-2H3/b4-3+/t12-,13-,14+,15-,17+/m1/s1; InChIKey=QJVXKWHHAMZTBY-GCPOEHJPSA-N; Ligustrin; Lilacin; MAGNOLENIN A; Methoxyconiferine; SMILES=COc1cc(cc(OC)c1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)\\C=C\\CO; Syrigin; Syringenin; Syringoside; beta-Terpineol
xref: CAS:118-34-3; FooDB:FDB011657; KEGG:C01533; KNApSAcK:C00000010
xref_mesh: MESH:C028305
xref: MetaCyc:CPD-63; PMID:23620140; PMID:23666001; PMID:23678812; PMID:31661774; PMID:33867336; PMID:34658231; PMID:35580997; PMID:35598514; PMID:35706960; PMID:35794555; PMID:36411652; PMID:36840496; PMID:37243678; PMID:37278329; PMID:37882327; PMID:38212029; PMID:38520788; PMID:38611823; Reaxys:97166; Wikipedia:Syringin
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Bax
BCL2 associated X, apoptosis regulator
increases expression
ISO
syringin results in increased expression of BAX protein
CTD
PMID:35580997
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
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Bcl2
BCL2, apoptosis regulator
decreases expression
ISO
syringin results in decreased expression of BCL2 protein
CTD
PMID:35580997
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
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Birc5
baculoviral IAP repeat-containing 5
decreases expression
ISO
syringin results in decreased expression of BIRC5 protein
CTD
PMID:35580997
NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155
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Ccl11
C-C motif chemokine ligand 11
multiple interactions
ISO
syringin inhibits the reaction [Ovalbumin results in increased expression of CCL11 protein]
CTD
PMID:33146439
NCBI chr10:67,525,975...67,530,576
Ensembl chr10:67,525,862...67,530,575
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Ccnd1
cyclin D1
increases expression
ISO
syringin results in increased expression of CCND1 protein
CTD
PMID:35580997
NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
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Cdh1
cadherin 1
increases expression
ISO
syringin results in increased expression of CDH1 protein
CTD
PMID:35580997
NCBI chr19:51,402,178...51,471,572
Ensembl chr19:51,402,034...51,471,565
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Ifng
interferon gamma
multiple interactions
ISO
syringin inhibits the reaction [Ovalbumin results in increased expression of IFNG protein]
CTD
PMID:33146439
NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216
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Il13
interleukin 13
multiple interactions
ISO
syringin inhibits the reaction [Ovalbumin results in increased expression of IL13 protein]
CTD
PMID:33146439
NCBI chr10:38,290,926...38,293,483
Ensembl chr10:38,290,926...38,293,483
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Il4
interleukin 4
multiple interactions
ISO
syringin inhibits the reaction [Ovalbumin results in increased expression of IL4 protein]
CTD
PMID:33146439
NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549
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Il5
interleukin 5
multiple interactions
ISO
syringin inhibits the reaction [Ovalbumin results in increased expression of IL5 protein]
CTD
PMID:33146439
NCBI chr10:38,375,132...38,378,003
Ensembl chr10:38,375,132...38,378,003
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Il6
interleukin 6
multiple interactions
ISO
syringin inhibits the reaction [Ovalbumin results in increased expression of IL6 protein]
CTD
PMID:33146439
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
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Mpo
myeloperoxidase
multiple interactions
ISO
syringin inhibits the reaction [Ovalbumin results in increased activity of MPO protein]
CTD
PMID:33146439
NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056
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Nfkbia
NFKB inhibitor alpha
multiple interactions
ISO
syringin inhibits the reaction [Ovalbumin results in increased expression of and results in increased phosphorylation of NFKBIA protein]
CTD
PMID:33146439
NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072
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Ppara
peroxisome proliferator activated receptor alpha
increases phosphorylation
ISO
syringin results in increased phosphorylation of PPARA protein
CTD
PMID:23691032
NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714
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Prkaa1
protein kinase AMP-activated catalytic subunit alpha 1
decreases phosphorylation
ISO
syringin results in decreased phosphorylation of PRKAA1 protein
CTD
PMID:23691032
NCBI chr 2:55,967,766...56,003,450
Ensembl chr 2:55,967,351...56,003,450
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Prkaa2
protein kinase AMP-activated catalytic subunit alpha 2
decreases phosphorylation
ISO
syringin results in decreased phosphorylation of PRKAA2 protein
CTD
PMID:23691032
NCBI chr 5:125,036,945...125,109,010
Ensembl chr 5:125,042,179...125,108,324
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Rela
RELA proto-oncogene, NF-kB subunit
multiple interactions
ISO
syringin inhibits the reaction [Ovalbumin results in increased expression of and results in increased phosphorylation of RELA protein]
CTD
PMID:33146439
NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
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Sqstm1
sequestosome 1
decreases expression
ISO
syringin results in decreased expression of SQSTM1 protein
CTD
PMID:35580997
NCBI chr10:35,026,598...35,037,750
Ensembl chr10:35,026,598...35,037,750
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Tnf
tumor necrosis factor
multiple interactions
ISO
syringin inhibits the reaction [Ovalbumin results in increased expression of TNF protein]
CTD
PMID:33146439
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
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Tp53
tumor protein p53
increases expression
ISO
syringin results in increased expression of TP53 protein
CTD
PMID:35580997
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
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