CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: Swertiamarin
Accession: CHEBI:9370
browse the term
Definition: A glycoside that has formula C16H22O10.
Synonyms: related_synonym: Formula=C16H22O10; InChI=1S/C16H22O10/c1-2-7-14(24-6-8-13(21)23-4-3-16(7,8)22)26-15-12(20)11(19)10(18)9(5-17)25-15/h2,6-7,9-12,14-15,17-20,22H,1,3-5H2/t7-,9+,10+,11-,12+,14-,15-,16+/m0/s1; InChIKey=HEYZWPRKKUGDCR-QBXMEVCASA-N; SMILES=OC[C@H]1O[C@@H](O[C@@H]2OC=C3C(=O)OCC[C@@]3(O)[C@H]2C=C)[C@H](O)[C@@H](O)[C@@H]1O
xref: CAS:17388-39-5; KEGG:C09800; KNApSAcK:C00003100
xref_mesh: MESH:C013270
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Acp3
acid phosphatase 3
multiple interactions
EXP
swertiamarin inhibits the reaction [Testosterone results in increased secretion of ACP3 protein]
CTD
PMID:27866977
NCBI chr 8:104,905,570...104,956,146
Ensembl chr 8:104,905,586...104,954,236
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Acta2
actin alpha 2, smooth muscle
multiple interactions
EXP
swertiamarin inhibits the reaction [Testosterone results in increased expression of ACTA2 mRNA]
CTD
PMID:27866977
NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
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Ar
androgen receptor
multiple interactions
EXP
swertiamarin inhibits the reaction [Testosterone results in increased expression of AR protein]
CTD
PMID:27866977
NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
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Bax
BCL2 associated X, apoptosis regulator
multiple interactions
EXP
swertiamarin inhibits the reaction [Testosterone results in decreased expression of BAX protein]
CTD
PMID:27866977
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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Bcl2
BCL2, apoptosis regulator
multiple interactions
EXP
swertiamarin inhibits the reaction [Testosterone results in increased expression of BCL2 protein]
CTD
PMID:27866977
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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Cdh1
cadherin 1
multiple interactions
EXP
swertiamarin inhibits the reaction [Testosterone results in decreased expression of CDH1 mRNA]
CTD
PMID:27866977
NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
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Egf
epidermal growth factor
multiple interactions
EXP
swertiamarin inhibits the reaction [Testosterone results in increased expression of EGF protein]
CTD
PMID:27866977
NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064
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Esr1
estrogen receptor 1
multiple interactions
EXP
swertiamarin inhibits the reaction [Testosterone results in increased expression of ESR1 protein]
CTD
PMID:27866977
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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Fgf2
fibroblast growth factor 2
multiple interactions
EXP
swertiamarin inhibits the reaction [Testosterone results in increased expression of FGF2 protein]
CTD
PMID:27866977
NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
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Hif1a
hypoxia inducible factor 1 subunit alpha
multiple interactions
EXP
swertiamarin inhibits the reaction [Testosterone results in increased expression of HIF1A protein]
CTD
PMID:27866977
NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
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Pcna
proliferating cell nuclear antigen
multiple interactions
EXP
swertiamarin inhibits the reaction [Testosterone results in increased expression of PCNA protein]
CTD
PMID:27866977
NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
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Ptgs2
prostaglandin-endoperoxide synthase 2
multiple interactions
EXP
swertiamarin inhibits the reaction [Testosterone results in increased expression of PTGS2 protein]
CTD
PMID:27866977
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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Twist1
twist family bHLH transcription factor 1
multiple interactions
EXP
swertiamarin inhibits the reaction [Testosterone results in increased expression of TWIST1 mRNA]
CTD
PMID:27866977
NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653
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Vim
vimentin
multiple interactions
EXP
swertiamarin inhibits the reaction [Testosterone results in increased expression of VIM mRNA]
CTD
PMID:27866977
NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
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