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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:sulfamethizole
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Accession:CHEBI:9331 term browser browse the term
Definition:A sulfonamide consisting of a 1,3,4-thiadiazole nucleus with a methyl substituent at C-5 and a 4-aminobenzenesulfonamido group at C-2.
Synonyms:exact_synonym: 4-amino-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide
 related_synonym: Formula=C9H10N4O2S2;   InChI=1S/C9H10N4O2S2/c1-6-11-12-9(16-6)13-17(14,15)8-4-2-7(10)3-5-8/h2-5H,10H2,1H3,(H,12,13);   InChIKey=VACCAVUAMIDAGB-UHFFFAOYSA-N;   Rufol;   SMILES=Cc1nnc(NS(=O)(=O)c2ccc(N)cc2)s1;   sulfamethizol;   sulfamethizolum;   sulfamethylthiadiazole;   sulfametizol;   sulphamethazole;   sulphamethiozole
 xref: CAS:144-82-1;   DrugBank:DB00576;   Drug_Central:2512;   KEGG:C08050;   KEGG:D00870;   LINCS:LSM-5455
 xref_mesh: MESH:D013419
 xref: PMID:11431418;   PMID:17180970;   PMID:20303138;   PMID:21275251;   Patent:US2447702;   Reaxys:255002;   Wikipedia:Sulfamethizole


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sulfamethizole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1b interleukin 1 beta multiple interactions ISO Sulfamethizole inhibits the reaction [Poloxalene results in increased expression of IL1B protein] CTD PMID:36799065 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions ISO Sulfamethizole inhibits the reaction [Poloxalene results in increased expression of MTOR protein] CTD PMID:36799065 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO Sulfamethizole inhibits the reaction [Poloxalene results in increased expression of TNF protein] CTD PMID:36799065 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19880
    role 19850
      biological role 19848
        antimicrobial agent 18250
          sulfamethizole 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19880
    subatomic particle 19878
      composite particle 19878
        hadron 19878
          baryon 19878
            nucleon 19878
              atomic nucleus 19878
                atom 19878
                  main group element atom 19817
                    p-block element atom 19817
                      chalcogen 19569
                        oxygen atom 19541
                          oxygen molecular entity 19541
                            hydroxides 19347
                              oxoacid 18782
                                chalcogen oxoacid 13784
                                  sulfur oxoacid 13573
                                    sulfonic acid 11618
                                      sulfonic acid derivative 11618
                                        sulfonamide 5307
                                          sulfonamide antibiotic 2928
                                            sulfamethizole 3
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