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G |
A2m |
alpha-2-macroglobulin |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of A2M mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of A2M mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 6:121,612,920...121,656,197
Ensembl chr 6:121,612,335...121,656,186
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G |
Abca1 |
ATP-binding cassette, sub-family A member 1 |
multiple interactions |
ISO |
[[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in decreased expression of ABCA1 mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of ABCA1 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of ABCA1 mRNA |
CTD |
PMID:35786680 |
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NCBI chr 4:53,030,789...53,159,988
Ensembl chr 4:53,030,787...53,159,895
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G |
Abcb11 |
ATP-binding cassette, sub-family B member 11 |
increases activity increases expression |
ISO EXP |
Streptozocin results in increased activity of ABCB11 protein Streptozocin results in increased expression of ABCB11 protein |
CTD |
PMID:12055592 PMID:23319174 |
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NCBI chr 2:69,068,626...69,172,960
Ensembl chr 2:69,068,626...69,172,958
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G |
Abcb1b |
ATP-binding cassette, sub-family B member 1B |
decreases expression increases expression |
EXP |
Streptozocin results in decreased expression of ABCB1B mRNA; Streptozocin results in decreased expression of ABCB1B protein Streptozocin results in increased expression of ABCB1B protein |
CTD |
PMID:22531820 PMID:23319174 |
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NCBI chr 5:8,848,147...8,916,314
Ensembl chr 5:8,848,147...8,916,315
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G |
Abcb4 |
ATP-binding cassette, sub-family B member 4 |
increases expression |
ISO |
Streptozocin results in increased expression of ABCB4 mRNA; Streptozocin results in increased expression of ABCB4 protein |
CTD |
PMID:12055592 |
|
NCBI chr 5:8,943,614...9,009,226
Ensembl chr 5:8,943,717...9,009,231
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G |
Abcc1 |
ATP-binding cassette, sub-family C member 1 |
increases expression |
EXP |
Streptozocin results in increased expression of ABCC1 mRNA; Streptozocin results in increased expression of ABCC1 protein |
CTD |
PMID:22531820 PMID:23319174 |
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NCBI chr16:14,179,317...14,292,743
Ensembl chr16:14,179,422...14,293,601
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G |
Abcc2 |
ATP-binding cassette, sub-family member 2 |
increases expression |
ISO EXP |
Streptozocin results in increased expression of ABCC2 mRNA Streptozocin results in increased expression of ABCC2 mRNA; Streptozocin results in increased expression of ABCC2 protein |
CTD |
PMID:11752103 PMID:22531820 PMID:23319174 |
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NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179
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G |
Abcc3 |
ATP-binding cassette, sub-family C member 3 |
decreases expression increases expression multiple interactions |
EXP ISO |
Streptozocin results in decreased expression of ABCC3 mRNA Streptozocin results in increased expression of ABCC3 mRNA; Streptozocin results in increased expression of ABCC3 protein [resveratrol co-treated with Streptozocin] results in increased expression of ABCC3 mRNA |
CTD |
PMID:22531820 PMID:23319174 PMID:25905778 |
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NCBI chr11:94,234,121...94,283,843
Ensembl chr11:94,234,121...94,283,823
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G |
Abcc4 |
ATP-binding cassette, sub-family C member 4 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of ABCC4 mRNA; Streptozocin results in increased expression of ABCC4 protein [Dietary Fats co-treated with Streptozocin] results in increased expression of ABCC4 mRNA |
CTD |
PMID:22531820 PMID:23319174 PMID:29382564 |
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NCBI chr14:118,720,104...118,945,475
Ensembl chr14:118,720,104...118,943,631
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G |
Abcc5 |
ATP-binding cassette, sub-family C member 5 |
increases expression |
EXP |
Streptozocin results in increased expression of ABCC5 mRNA; Streptozocin results in increased expression of ABCC5 protein |
CTD |
PMID:22531820 PMID:23319174 |
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NCBI chr16:20,150,053...20,245,178
Ensembl chr16:20,150,053...20,245,144
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G |
Abcc6 |
ATP-binding cassette, sub-family C member 6 |
decreases expression |
EXP |
Streptozocin results in decreased expression of ABCC6 protein |
CTD |
PMID:22531820 |
|
NCBI chr 7:45,625,804...45,679,915
Ensembl chr 7:45,616,979...45,679,726
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G |
Abcg2 |
ATP binding cassette subfamily G member 2 (Junior blood group) |
increases expression |
EXP |
Streptozocin results in increased expression of ABCG2 mRNA; Streptozocin results in increased expression of ABCG2 protein |
CTD |
PMID:23319174 |
|
NCBI chr 6:58,561,476...58,669,436
Ensembl chr 6:58,561,508...58,672,661
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G |
Abcg5 |
ATP binding cassette subfamily G member 5 |
increases expression |
EXP |
Streptozocin results in increased expression of ABCG5 mRNA |
CTD |
PMID:23319174 |
|
NCBI chr17:84,965,602...84,990,439
Ensembl chr17:84,965,662...84,990,439
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G |
Abcg8 |
ATP binding cassette subfamily G member 8 |
increases expression |
EXP |
Streptozocin results in increased expression of ABCG8 mRNA |
CTD |
PMID:23319174 |
|
NCBI chr17:84,983,730...85,007,761
Ensembl chr17:84,983,730...85,007,761
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G |
Abhd2 |
abhydrolase domain containing 2 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of ABHD2 mRNA |
CTD |
PMID:29127188 |
|
NCBI chr 7:78,923,002...79,015,257
Ensembl chr 7:78,922,947...79,015,256
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G |
Acaca |
acetyl-Coenzyme A carboxylase alpha |
multiple interactions decreases expression decreases activity increases expression |
ISO EXP |
Fructose inhibits the reaction [Streptozocin results in decreased activity of ACACA protein]; Fructose inhibits the reaction [Streptozocin results in decreased expression of ACACA mRNA]; Triiodothyronine inhibits the reaction [Streptozocin results in decreased activity of ACACA protein]; Triiodothyronine inhibits the reaction [Streptozocin results in decreased expression of ACACA mRNA] Streptozocin results in increased expression of ACACA mRNA [Dietary Fats co-treated with Streptozocin] results in increased expression of ACACA mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of ACACA mRNA; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of ACACA mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of ACACA mRNA] |
CTD |
PMID:1973097 PMID:28822685 PMID:33812996 PMID:39047806 |
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NCBI chr11:84,020,461...84,292,477
Ensembl chr11:84,020,498...84,292,477
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G |
Acadm |
acyl-Coenzyme A dehydrogenase, medium chain |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of ACADM protein Trientine inhibits the reaction [Streptozocin results in decreased expression of ACADM protein] |
CTD |
PMID:19634143 |
|
NCBI chr 3:153,627,990...153,650,280
Ensembl chr 3:153,627,994...153,650,269
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G |
Acat1 |
acetyl-Coenzyme A acetyltransferase 1 |
decreases expression multiple interactions |
ISO EXP |
Streptozocin results in decreased expression of ACAT1 protein Trientine inhibits the reaction [Streptozocin results in decreased expression of ACAT1 protein] Acrylamide inhibits the reaction [Streptozocin results in decreased expression of ACAT1 mRNA] |
CTD |
PMID:19634143 PMID:34896238 |
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NCBI chr 9:53,491,822...53,521,650
Ensembl chr 9:53,491,822...53,521,682
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G |
Acbd6 |
acyl-Coenzyme A binding domain containing 6 |
increases expression |
ISO |
Streptozocin results in increased expression of ACBD6 mRNA |
CTD |
PMID:25905778 |
|
NCBI chr 1:155,433,845...155,564,120
Ensembl chr 1:155,433,866...155,567,076
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G |
Ace |
angiotensin I converting enzyme |
multiple interactions increases expression increases activity |
ISO EXP |
[INS1 protein co-treated with Pravastatin] inhibits the reaction [Streptozocin results in increased expression of ACE protein]; Bezafibrate inhibits the reaction [Streptozocin results in increased expression of ACE mRNA]; Bezafibrate inhibits the reaction [Streptozocin results in increased expression of ACE protein]; Enalapril inhibits the reaction [Streptozocin results in increased expression of ACE mRNA]; Enalapril inhibits the reaction [Streptozocin results in increased expression of ACE protein]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of ACE mRNA]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of ACE protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of ACE mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of ACE mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of ACE protein] Streptozocin results in increased expression of ACE mRNA; Streptozocin results in increased expression of ACE protein Streptozocin results in increased activity of ACE protein 2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of ACE mRNA]; [Streptozocin co-treated with Niacinamide] results in increased expression of ACE mRNA; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of ACE protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of ACE mRNA] |
CTD |
PMID:15793251 PMID:16979161 PMID:22191573 PMID:23733546 PMID:28468961 PMID:29266779 PMID:29682576 PMID:37120126 More...
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NCBI chr11:105,858,774...105,880,790
Ensembl chr11:105,858,771...105,880,790
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G |
Ace2 |
angiotensin converting enzyme 2 |
decreases expression multiple interactions increases activity |
EXP ISO |
Streptozocin results in decreased expression of ACE2 protein 2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of ACE2 mRNA]; [Streptozocin co-treated with Niacinamide] results in decreased expression of ACE2 mRNA; CEBPB protein inhibits the reaction [Streptozocin results in decreased expression of ACE2 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of ACE2 mRNA]; Telmisartan inhibits the reaction [Streptozocin results in decreased expression of ACE2 protein] [INS1 protein co-treated with Pravastatin] inhibits the reaction [Streptozocin results in decreased expression of ACE2 protein]; ACE2 inhibits the reaction [Streptozocin results in increased expression of AGT protein modified form]; ACE2 inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; ACE2 inhibits the reaction [Streptozocin results in increased expression of VEGFA protein] Streptozocin results in increased activity of ACE2 protein |
CTD |
PMID:20844835 PMID:21381899 PMID:28468961 PMID:29266779 PMID:29682576 PMID:37120126 More...
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NCBI chr X:162,922,338...162,971,414
Ensembl chr X:162,922,328...162,971,416
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G |
Acer2 |
alkaline ceramidase 2 |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of ACER2 mRNA |
CTD |
PMID:25905778 |
|
NCBI chr 4:86,792,585...86,853,059
Ensembl chr 4:86,792,633...86,853,059
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G |
Ache |
acetylcholinesterase |
multiple interactions increases activity decreases activity |
EXP ISO |
Acetylcysteine inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Alendronate inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; bisphenol A diglycidyl ether inhibits the reaction [Lisinopril inhibits the reaction [Streptozocin results in increased activity of ACHE protein]]; bisphenol A diglycidyl ether inhibits the reaction [Telmisartan inhibits the reaction [Streptozocin results in increased activity of ACHE protein]]; Curcumin inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Donepezil inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Genistein inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Indinavir inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Lisinopril inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Physostigmine inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Telmisartan inhibits the reaction [Streptozocin results in increased activity of ACHE protein] [Fructose co-treated with Streptozocin] results in increased expression of ACHE protein; [Propolis co-treated with Chlorpyrifos co-treated with Streptozocin] results in decreased activity of ACHE protein; [Propolis co-treated with Streptozocin] inhibits the reaction [Chlorpyrifos results in decreased activity of ACHE protein]; [Streptozocin co-treated with Chlorpyrifos] results in decreased activity of ACHE protein; [Streptozocin co-treated with Dietary Fats] results in increased activity of ACHE protein; alpha-Tocopherol inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Canagliflozin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased activity of ACHE protein]; Chlorpyrifos inhibits the reaction [Streptozocin results in decreased activity of ACHE protein]; Donepezil inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; geraniol inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Melatonin inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Metformin inhibits the reaction [[Fructose co-treated with Streptozocin] results in increased expression of ACHE protein]; Phycocyanin inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Propolis inhibits the reaction [[Streptozocin co-treated with Chlorpyrifos] results in decreased activity of ACHE protein]; Propolis inhibits the reaction [Streptozocin results in decreased activity of ACHE protein]; pyrazolanthrone inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Rivastigmine inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Streptozocin inhibits the reaction [Chlorpyrifos results in decreased activity of ACHE protein]; Streptozocin promotes the reaction [[Propolis co-treated with Chlorpyrifos] results in decreased activity of ACHE protein]; Tocotrienols inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; vanillin inhibits the reaction [[Fructose co-treated with Streptozocin] results in increased expression of ACHE protein] |
CTD |
PMID:18208924 PMID:18343489 PMID:19464315 PMID:19705549 PMID:20369229 PMID:20600246 PMID:23060470 PMID:24752916 PMID:27087133 PMID:27566243 PMID:28259689 PMID:28499986 PMID:30120923 PMID:30481507 PMID:31400774 PMID:32805344 PMID:33823243 PMID:37354076 More...
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NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728
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G |
Acmsd |
amino carboxymuconate semialdehyde decarboxylase |
increases activity increases expression |
ISO |
Streptozocin results in increased activity of ACMSD protein Streptozocin results in increased expression of ACMSD mRNA |
CTD |
PMID:12042425 |
|
NCBI chr 1:127,657,149...127,695,723
Ensembl chr 1:127,657,150...127,695,715
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G |
Aco2 |
aconitase 2, mitochondrial |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of ACO2 protein Trientine inhibits the reaction [Streptozocin results in decreased expression of ACO2 protein] |
CTD |
PMID:19634143 |
|
NCBI chr15:81,756,664...81,799,338
Ensembl chr15:81,756,510...81,799,334
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G |
Acot1 |
acyl-CoA thioesterase 1 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of ACOT1 mRNA |
CTD |
PMID:29127188 |
|
NCBI chr12:84,056,276...84,064,444
Ensembl chr12:84,056,264...84,065,145
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G |
Acot2 |
acyl-CoA thioesterase 2 |
multiple interactions |
ISO EXP |
[resveratrol co-treated with Streptozocin] results in decreased expression of ACOT2 mRNA [Streptozocin co-treated with Dietary Fats] results in increased expression of ACOT2 mRNA |
CTD |
PMID:25905778 PMID:29127188 |
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NCBI chr12:84,034,635...84,040,651
Ensembl chr12:84,034,635...84,040,647
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G |
Acot9 |
acyl-CoA thioesterase 9 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of ACOT9 mRNA |
CTD |
PMID:29127188 |
|
NCBI chr X:154,045,439...154,080,650
Ensembl chr X:154,045,439...154,080,650
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G |
Acox1 |
acyl-Coenzyme A oxidase 1, palmitoyl |
multiple interactions |
ISO |
[[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of ACOX1 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of ACOX1 mRNA |
CTD |
PMID:35786680 |
|
NCBI chr11:116,062,714...116,089,605
Ensembl chr11:116,062,714...116,089,871
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G |
Acp5 |
acid phosphatase 5, tartrate resistant |
multiple interactions increases activity increases expression |
EXP |
formononetin inhibits the reaction [Streptozocin results in increased activity of ACP5 protein]; formononetin inhibits the reaction [Streptozocin results in increased expression of ACP5 mRNA] |
CTD |
PMID:35315182 |
|
NCBI chr 9:22,038,023...22,047,042
Ensembl chr 9:22,038,023...22,047,007
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G |
Acsm2 |
acyl-CoA synthetase medium-chain family member 2 |
increases expression |
ISO |
Streptozocin results in increased expression of ACSM2 mRNA |
CTD |
PMID:25905778 |
|
NCBI chr 7:119,153,563...119,199,917
Ensembl chr 7:119,153,563...119,199,913
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G |
Acss1 |
acyl-CoA synthetase short-chain family member 1 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of ACSS1 mRNA |
CTD |
PMID:29127188 |
|
NCBI chr 2:150,460,031...150,510,160
Ensembl chr 2:150,460,025...150,510,420
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G |
Acta2 |
actin alpha 2, smooth muscle, aorta |
multiple interactions increases expression decreases expression |
ISO EXP |
[Streptozocin co-treated with Fructose] results in increased expression of ACTA2 protein; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of ACTA2 protein]; Metformin promotes the reaction [dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of ACTA2 protein]] [Dietary Fats co-treated with Streptozocin] results in increased expression of ACTA2 mRNA; [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of ACTA2 mRNA]; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of ACTA2 mRNA; [Streptozocin co-treated with fatostatin] results in increased expression of ACTA2 protein; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of ACTA2 mRNA; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of ACTA2 protein; bisphenol A inhibits the reaction [Streptozocin results in decreased expression of ACTA2 protein]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of ACTA2 mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of ACTA2 mRNA] Streptozocin results in increased expression of ACTA2 protein |
CTD |
PMID:29420703 PMID:29988851 PMID:30551545 PMID:35051763 PMID:35993117 PMID:38282657 PMID:39047806 More...
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NCBI chr19:34,217,736...34,232,985
Ensembl chr19:34,218,490...34,232,990
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G |
Actc1 |
actin, alpha, cardiac muscle 1 |
decreases expression |
ISO |
Streptozocin results in decreased expression of ACTC1 protein |
CTD |
PMID:21136691 |
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NCBI chr 2:113,877,763...113,883,356
Ensembl chr 2:113,877,763...113,884,029
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G |
Actn4 |
actinin alpha 4 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of ACTN4 protein Trientine inhibits the reaction [Streptozocin results in increased expression of ACTN4 protein] |
CTD |
PMID:19634143 |
|
NCBI chr 7:28,592,673...28,661,799
Ensembl chr 7:28,592,673...28,661,765
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G |
Acy1 |
aminoacylase 1 |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of ACY1 protein Trientine inhibits the reaction [Streptozocin results in decreased expression of ACY1 protein] |
CTD |
PMID:19634143 |
|
NCBI chr 9:106,310,180...106,315,594
Ensembl chr 9:106,310,180...106,315,518
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G |
Ada |
adenosine deaminase |
multiple interactions increases activity |
ISO |
[Zinc Sulfate results in increased abundance of Zinc] inhibits the reaction [Streptozocin results in increased activity of ADA protein] |
CTD |
PMID:32864810 |
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NCBI chr 2:163,565,703...163,592,154
Ensembl chr 2:163,568,504...163,592,159
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G |
Adam17 |
a disintegrin and metallopeptidase domain 17 |
multiple interactions increases expression |
ISO |
Diosgenin inhibits the reaction [Streptozocin results in increased expression of ADAM17 mRNA]; Diosgenin inhibits the reaction [Streptozocin results in increased expression of ADAM17 protein] Streptozocin results in increased expression of ADAM17 mRNA; Streptozocin results in increased expression of ADAM17 protein |
CTD |
PMID:35305976 |
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NCBI chr12:21,373,510...21,423,633
Ensembl chr12:21,373,510...21,423,633
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G |
Adgre1 |
adhesion G protein-coupled receptor E1 |
multiple interactions increases expression |
ISO EXP |
stannous mesoporphyrin inhibits the reaction [4-(4-(3-adamantan-1-ylureido)cyclohexyloxy)benzoic acid inhibits the reaction [Streptozocin results in increased expression of ADGRE1 protein]] [fatostatin co-treated with Streptozocin] results in increased expression of ADGRE1 mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of ADGRE1 mRNA; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of ADGRE1 mRNA] Streptozocin results in increased expression of ADGRE1 mRNA |
CTD |
PMID:23611540 PMID:29420703 PMID:39047806 |
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NCBI chr17:57,665,650...57,790,527
Ensembl chr17:57,665,691...57,790,527
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G |
Adgrg7 |
adhesion G protein-coupled receptor G7 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of ADGRG7 mRNA |
CTD |
PMID:33484791 |
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NCBI chr16:56,544,972...56,616,369
Ensembl chr16:56,544,972...56,616,218
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G |
Adh1 |
alcohol dehydrogenase 1 (class I) |
increases expression |
ISO |
Streptozocin results in increased expression of ADH1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 3:137,983,346...137,996,459
Ensembl chr 3:137,966,752...137,996,459
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G |
Adipoq |
adiponectin, C1Q and collagen domain containing |
multiple interactions decreases expression decreases secretion |
ISO EXP |
1,3-dimethoxy-5-methyl-2-(3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl)benzene inhibits the reaction [4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in decreased secretion of ADIPOQ protein]]; 4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in decreased secretion of ADIPOQ protein]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of ADIPOQ protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of ADIPOQ protein; Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOQ mRNA]; Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOQ protein]; Allopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOQ mRNA]]; Allopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOQ protein]]; cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of ADIPOQ protein]; geraniol promotes the reaction [Streptozocin results in decreased expression of ADIPOQ protein]; morin analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of ADIPOQ protein]; Warfarin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of ADIPOQ protein]; Zinc Compounds inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein] Streptozocin results in decreased expression of ADIPOQ mRNA; Streptozocin results in decreased expression of ADIPOQ protein [Dietary Fats co-treated with Streptozocin] results in decreased expression of and results in decreased secretion of ADIPOQ protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of and results in decreased secretion of ADIPOQ protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein]; omaveloxolone analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein] |
CTD |
PMID:17270171 PMID:21439372 PMID:21912612 PMID:22675305 PMID:24854284 PMID:27488359 PMID:28178614 PMID:29274332 PMID:29988851 PMID:32410268 PMID:32495657 PMID:37337224 PMID:37482253 More...
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NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778
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G |
Adipor1 |
adiponectin receptor 1 |
decreases expression multiple interactions increases expression |
ISO |
Streptozocin results in decreased expression of ADIPOR1 protein 1,3-dimethoxy-5-methyl-2-(3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl)benzene inhibits the reaction [4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in increased expression of ADIPOR1 protein]]; 4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in increased expression of ADIPOR1 protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of ADIPOR1 protein] |
CTD |
PMID:17270171 PMID:24413998 PMID:29274332 |
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NCBI chr 1:134,343,116...134,361,089
Ensembl chr 1:134,343,116...134,361,089
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G |
Adipor2 |
adiponectin receptor 2 |
multiple interactions decreases expression |
ISO |
Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOR2 protein]; Allopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOR2 protein]] |
CTD |
PMID:21912612 |
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NCBI chr 6:119,330,111...119,394,489
Ensembl chr 6:119,330,111...119,394,665
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G |
Adora2a |
adenosine A2a receptor |
increases expression |
EXP |
Streptozocin results in increased expression of ADORA2A protein |
CTD |
PMID:26654777 |
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NCBI chr10:75,152,711...75,170,626
Ensembl chr10:75,152,711...75,170,618
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G |
Adra1a |
adrenergic receptor, alpha 1a |
increases expression |
ISO |
Streptozocin results in increased expression of ADRA1A mRNA; Streptozocin results in increased expression of ADRA1A protein |
CTD |
PMID:19133277 |
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NCBI chr14:66,872,705...67,009,549
Ensembl chr14:66,872,700...67,008,617
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G |
Adra1b |
adrenergic receptor, alpha 1b |
increases expression |
ISO |
Streptozocin results in increased expression of ADRA1B mRNA |
CTD |
PMID:19298542 |
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NCBI chr11:43,665,432...43,792,076
Ensembl chr11:43,665,433...43,792,037
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G |
Adra1d |
adrenergic receptor, alpha 1d |
decreases expression |
ISO |
Streptozocin results in decreased expression of ADRA1D mRNA |
CTD |
PMID:19298542 |
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NCBI chr 2:131,387,277...131,404,417
Ensembl chr 2:131,387,770...131,404,203
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G |
Adrb1 |
adrenergic receptor, beta 1 |
multiple interactions decreases expression |
ISO |
Metoprolol inhibits the reaction [Streptozocin results in decreased expression of ADRB1 protein] |
CTD |
PMID:18703049 |
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NCBI chr19:56,710,549...56,713,582
Ensembl chr19:56,710,631...56,721,545
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G |
Adrb2 |
adrenergic receptor, beta 2 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of ADRB2 protein Metoprolol promotes the reaction [Streptozocin results in increased expression of ADRB2 protein] |
CTD |
PMID:18703049 |
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NCBI chr18:62,310,784...62,313,052
Ensembl chr18:62,310,887...62,313,030
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G |
Adrb3 |
adrenergic receptor, beta 3 |
multiple interactions increases expression |
ISO |
Metoprolol promotes the reaction [Streptozocin results in increased expression of ADRB3 protein] |
CTD |
PMID:18703049 |
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NCBI chr 8:27,715,804...27,720,833
Ensembl chr 8:27,715,804...27,740,644
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G |
Afmid |
arylformamidase |
increases expression |
ISO |
Streptozocin results in increased expression of AFMID mRNA |
CTD |
PMID:25905778 |
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NCBI chr11:117,716,329...117,730,734
Ensembl chr11:117,716,750...117,730,734
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G |
Afp |
alpha fetoprotein |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of AFP mRNA |
CTD |
PMID:29127188 |
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NCBI chr 5:90,638,573...90,656,766
Ensembl chr 5:90,638,596...90,656,766
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G |
Ager |
advanced glycosylation end product-specific receptor |
increases expression multiple interactions increases response to substance |
ISO EXP |
Streptozocin results in increased expression of AGER mRNA; Streptozocin results in increased expression of AGER protein [Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of AGER protein]; [Streptozocin co-treated with Dietary Fats] results in increased expression of AGER protein; Dimethyl Fumarate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of AGER protein]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of AGER protein]; Kangen-karyu inhibits the reaction [Streptozocin results in increased expression of AGER protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of AGER protein]; procyanidin B2 inhibits the reaction [Streptozocin results in increased expression of AGER protein]; Sodium Selenite inhibits the reaction [Streptozocin results in increased expression of AGER protein]; Zinc inhibits the reaction [Streptozocin results in increased expression of AGER mRNA] manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Streptozocin results in increased expression of AGER mRNA] AGER protein results in increased susceptibility to Streptozocin |
CTD |
PMID:19397970 PMID:19833897 PMID:22476978 PMID:25199697 PMID:27109771 PMID:31009641 PMID:36999408 More...
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NCBI chr17:34,816,545...34,819,911
Ensembl chr17:34,816,836...34,819,910
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G |
Agrp |
agouti related neuropeptide |
multiple interactions increases expression |
ISO |
INS protein inhibits the reaction [Streptozocin results in increased expression of AGRP mRNA] |
CTD |
PMID:20219977 |
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NCBI chr 8:106,293,327...106,306,477
Ensembl chr 8:106,293,330...106,364,025
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G |
Agt |
angiotensinogen |
multiple interactions increases expression decreases abundance |
EXP ISO |
CEBPB protein affects the reaction [Streptozocin results in increased expression of AGT protein]; CEBPB protein inhibits the reaction [Streptozocin results in decreased abundance of AGT protein modified form]; IGF1 protein inhibits the reaction [Streptozocin results in increased expression of AGT protein]; Valsartan inhibits the reaction [Streptozocin results in decreased abundance of AGT protein modified form]; Valsartan promotes the reaction [Streptozocin results in increased expression of AGT protein] ACE2 inhibits the reaction [Streptozocin results in increased expression of AGT protein modified form]; AGT protein modified form inhibits the reaction [Streptozocin results in decreased abundance of Cyclic GMP]; AGT protein modified form inhibits the reaction [Streptozocin results in increased expression of PDE5 mRNA]; benazepril inhibits the reaction [Streptozocin results in increased expression of AGT protein modified form]; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in increased expression of AGT protein] Streptozocin results in increased expression of AGT mRNA; Streptozocin results in increased expression of AGT protein; Streptozocin results in increased expression of AGT protein modified form |
CTD |
PMID:11375343 PMID:15643138 PMID:17724226 PMID:18487452 PMID:20547220 PMID:20844835 PMID:28299329 PMID:28468961 PMID:29266779 More...
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NCBI chr 8:125,283,326...125,296,445
Ensembl chr 8:125,283,273...125,296,445
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G |
Agtr1a |
angiotensin II receptor, type 1a |
multiple interactions increases expression |
EXP ISO |
2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of AGTR1A mRNA]; [Perindopril co-treated with AM6545] inhibits the reaction [Streptozocin results in increased expression of AGTR1A protein]; [Streptozocin co-treated with Niacinamide] results in increased expression of AGTR1A mRNA; AM6545 inhibits the reaction [Streptozocin results in increased expression of AGTR1A mRNA]; AM6545 inhibits the reaction [Streptozocin results in increased expression of AGTR1A protein]; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of AGTR1 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of AGTR1A mRNA]; Perindopril inhibits the reaction [Streptozocin results in increased expression of AGTR1A mRNA]; Perindopril inhibits the reaction [Streptozocin results in increased expression of AGTR1A protein]; Telmisartan inhibits the reaction [Streptozocin results in increased expression of AGTR1A protein]; Valsartan promotes the reaction [Streptozocin results in increased expression of AGTR1 protein] Streptozocin results in increased expression of AGTR1 protein; Streptozocin results in increased expression of AGTR1A mRNA; Streptozocin results in increased expression of AGTR1A protein [Streptozocin co-treated with Dietary Fats] results in increased expression of AGTR1A mRNA; esculetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of AGTR1A mRNA] |
CTD |
PMID:17724226 PMID:18487452 PMID:21381899 PMID:28946194 PMID:29266779 PMID:30184259 PMID:37120126 More...
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NCBI chr13:30,520,339...30,566,850
Ensembl chr13:30,520,424...30,566,850
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G |
Agtr2 |
angiotensin II receptor, type 2 |
increases expression multiple interactions |
EXP ISO |
Streptozocin results in increased expression of AGTR2 mRNA; Streptozocin results in increased expression of AGTR2 protein [Streptozocin co-treated with Dietary Fats] results in increased expression of AGTR2 mRNA; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in increased expression of AGTR2 mRNA]; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in increased expression of AGTR2 protein]; esculetin promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of AGTR2 mRNA] CEBPB protein inhibits the reaction [Streptozocin results in increased expression of AGTR2 protein]; Valsartan inhibits the reaction [Streptozocin results in increased expression of AGTR2 protein] |
CTD |
PMID:15587404 PMID:17724226 PMID:28946194 PMID:29266779 |
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NCBI chr X:21,350,863...21,355,072
Ensembl chr X:21,350,783...21,355,403
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G |
Agxt2 |
alanine-glyoxylate aminotransferase 2 |
multiple interactions decreases expression |
ISO |
Trientine inhibits the reaction [Streptozocin results in decreased expression of AGXT2 protein] |
CTD |
PMID:19634143 |
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NCBI chr15:10,358,602...10,410,244
Ensembl chr15:10,358,618...10,410,239
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G |
Ahcy |
S-adenosylhomocysteine hydrolase |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of AHCY mRNA; [Streptozocin co-treated with Dietary Fats] results in increased methylation of AHCY gene |
CTD |
PMID:29127188 |
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NCBI chr 2:154,901,230...154,916,417
Ensembl chr 2:154,901,230...154,916,417
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G |
Ahr |
aryl-hydrocarbon receptor |
decreases expression |
EXP |
Streptozocin results in decreased expression of AHR mRNA |
CTD |
PMID:22531820 |
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NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037
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G |
Aifm1 |
apoptosis-inducing factor, mitochondrion-associated 1 |
increases expression multiple interactions |
ISO EXP |
Streptozocin results in increased expression of AIFM1 protein Trientine inhibits the reaction [Streptozocin results in increased expression of AIFM1 protein] [Streptozocin co-treated with NQO1 protein mutant form] results in increased expression of AIFM1 protein; FGF21 protein affects the reaction [Streptozocin results in increased expression of AIFM1] |
CTD |
PMID:19634143 PMID:23458895 PMID:23499715 |
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NCBI chr X:47,563,821...47,602,440
Ensembl chr X:47,563,821...47,602,440
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G |
Ajm1 |
apical junction component 1 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of AJM1 mRNA |
CTD |
PMID:33484791 |
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NCBI chr 2:25,465,428...25,471,760
Ensembl chr 2:25,465,428...25,471,769
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G |
Ak4 |
adenylate kinase 4 |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of AK4 protein Trientine inhibits the reaction [Streptozocin results in decreased expression of AK4 protein] |
CTD |
PMID:19634143 |
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NCBI chr 4:101,273,675...101,324,968
Ensembl chr 4:101,276,474...101,324,192
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G |
Akr1a1 |
aldo-keto reductase family 1, member A1 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of AKR1A1 protein Trientine inhibits the reaction [Streptozocin results in increased expression of AKR1A1 protein] |
CTD |
PMID:19634143 |
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NCBI chr 4:116,493,707...116,508,871
Ensembl chr 4:116,493,707...116,508,877
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G |
Akr1b1 |
aldo-keto reductase family 1 member B |
multiple interactions |
ISO |
Streptozocin inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK1 protein]; Streptozocin inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK3 protein]; Streptozocin inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK8 protein]; Streptozocin inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK9 protein] |
CTD |
PMID:25541468 |
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NCBI chr 6:34,280,865...34,294,424
Ensembl chr 6:34,279,369...34,294,413
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G |
Akr1c18 |
aldo-keto reductase family 1, member C18 |
multiple interactions |
ISO EXP |
[resveratrol co-treated with Streptozocin] results in decreased expression of AKR1C3 mRNA [Streptozocin co-treated with Dietary Fats] results in increased expression of AKR1C18 mRNA |
CTD |
PMID:25905778 PMID:29127188 |
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NCBI chr13:4,182,614...4,200,645
Ensembl chr13:4,182,614...4,200,653
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G |
Akt1 |
thymoma viral proto-oncogene 1 |
multiple interactions decreases expression decreases phosphorylation increases phosphorylation increases expression decreases expression |
ISO EXP |
[cobaltiprotoporphyrin co-treated with Streptozocin] results in increased phosphorylation of AKT1 protein; [Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of AKT1 protein; [Dietary Fats co-treated with Streptozocin] results in increased phosphorylation of AKT1 protein; [Resveratrol co-treated with Streptozocin] results in decreased phosphorylation of AKT1 protein; [Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in decreased phosphorylation of AKT1 protein; [Streptozocin co-treated with Niacinamide] results in decreased phosphorylation of AKT1 protein; asiatic acid inhibits the reaction [Streptozocin results in decreased expression of AKT1 protein]; cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased phosphorylation of AKT1 protein]; Curcumin inhibits the reaction [Streptozocin results in decreased phosphorylation of AKT1 protein]; dapagliflozin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of AKT1 protein]; eupafolin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased phosphorylation of AKT1 protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of AKT1 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in decreased phosphorylation of AKT1 protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of AKT1 mRNA]; morin inhibits the reaction [Streptozocin results in increased expression of AKT1 mRNA]; myrtenal inhibits the reaction [Streptozocin results in decreased expression of AKT1 protein]; nerolidol inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased phosphorylation of AKT1 protein]; Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of AKT1 mRNA]; piperlongumine inhibits the reaction [Streptozocin results in decreased expression of AKT1 protein]; Plant Extracts inhibits the reaction [[Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in decreased phosphorylation of AKT1 protein]; Propofol promotes the reaction [Streptozocin results in decreased phosphorylation of AKT1 protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased phosphorylation of AKT1 protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of AKT1 mRNA]; Rivastigmine inhibits the reaction [Streptozocin results in decreased expression of AKT1 mRNA]; Streptozocin results in decreased expression of and results in decreased phosphorylation of AKT1 protein; STUB1 inhibits the reaction [Streptozocin results in decreased expression of AKT1 protein]; tin mesoporphyrin inhibits the reaction [[cobaltiprotoporphyrin co-treated with Streptozocin] results in increased phosphorylation of AKT1 protein]; Tribulus extract inhibits the reaction [Streptozocin results in decreased phosphorylation of AKT1 protein]; Wortmannin inhibits the reaction [Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of AKT1 mRNA]] Streptozocin results in decreased expression of AKT1 mRNA; Streptozocin results in decreased expression of AKT1 protein [Dietary Fats co-treated with Streptozocin] results in decreased expression of AKT1 mRNA; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of AKT1 protein; [Streptozocin co-treated with CNR1 protein] affects the phosphorylation of AKT1 protein; [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased phosphorylation of AKT1 protein; [Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of AKT1 protein; Metformin inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of AKT1 protein]; Metformin inhibits the reaction [Streptozocin results in decreased phosphorylation of AKT1 protein]; perilla seed oil inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of AKT1 protein]; phillyrin inhibits the reaction [Streptozocin results in decreased phosphorylation of AKT1 protein] streptozocin increases phosphorylation of Akt1 protein in heart Streptozotocin decreases expression of Akt1 protein in the liver Streptozocin decreases phosphorylation of Akt1 protein in the liver |
CTD RGD |
PMID:16595661 PMID:19002579 PMID:22675305 PMID:24810525 PMID:25541178 PMID:26071184 PMID:26286522 PMID:27417257 PMID:30721768 PMID:31743741 PMID:31877369 PMID:32805344 PMID:33359794 PMID:33484791 PMID:33724628 PMID:34391751 PMID:34649470 PMID:35414346 PMID:35442559 PMID:36169646 PMID:36627075 PMID:37081038 PMID:37566541 PMID:38706688 PMID:36044268 PMID:30186875 PMID:29379801 More...
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RGD:156430337, RGD:14401598, RGD:408346751 |
NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318
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G |
Akt2 |
thymoma viral proto-oncogene 2 |
multiple interactions |
ISO |
[Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of AKT2 protein; Butyric Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of AKT2 protein]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of AKT2 protein] |
CTD |
PMID:27270450 |
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NCBI chr 7:27,290,977...27,340,251
Ensembl chr 7:27,290,977...27,340,251
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G |
Alad |
aminolevulinate, delta-, dehydratase |
multiple interactions |
EXP |
[Streptozocin results in increased abundance of Blood Glucose] which results in decreased expression of ALAD protein; alpha-Tocopherol inhibits the reaction [[Streptozocin results in increased abundance of Blood Glucose] which results in decreased expression of ALAD protein] |
CTD |
PMID:7728901 |
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NCBI chr 4:62,422,762...62,438,300
Ensembl chr 4:62,427,406...62,438,155
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G |
Alas1 |
aminolevulinic acid synthase 1 |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of ALAS1 mRNA vanadyl sulfate inhibits the reaction [Streptozocin results in decreased expression of ALAS1 mRNA] |
CTD |
PMID:16684804 |
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NCBI chr 9:106,110,654...106,125,153
Ensembl chr 9:106,110,654...106,125,853
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G |
Alb |
albumin |
multiple interactions increases secretion decreases expression increases expression |
EXP ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Carboxymethylcellulose Sodium] results in increased expression of ALB protein; AM6545 inhibits the reaction [Streptozocin results in increased expression of ALB protein]; naringenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Carboxymethylcellulose Sodium] results in increased expression of ALB protein]; Perindopril inhibits the reaction [Streptozocin results in increased expression of ALB protein]; TXN protein inhibits the reaction [Streptozocin results in increased secretion of ALB protein] [bisphenol A co-treated with Streptozocin] results in decreased expression of ALB protein; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of ALB protein; [Streptozocin co-treated with Cadmium] results in increased expression of ALB protein; [Streptozocin co-treated with Cholesterol, Dietary] results in increased secretion of ALB protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of ALB protein; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of ALB protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of ALB protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of ALB protein]; Eugenol inhibits the reaction [Streptozocin results in decreased expression of ALB protein]; Gallic Acid inhibits the reaction [Streptozocin results in decreased expression of ALB protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Cholesterol, Dietary] results in increased secretion of ALB protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of ALB protein]; hesperetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of ALB protein]; LR-90 inhibits the reaction [Streptozocin results in increased expression of ALB protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of ALB protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of ALB protein]; Plant Extracts inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of ALB protein]; procyanidin B2 inhibits the reaction [Streptozocin results in increased expression of ALB protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of ALB protein] |
CTD |
PMID:12845431 PMID:14871415 PMID:17360766 PMID:18204486 PMID:21450970 PMID:24923654 PMID:25199697 PMID:25240712 PMID:29331653 PMID:30184259 PMID:31063766 PMID:33639173 PMID:34922902 PMID:35187753 PMID:36510688 PMID:38047382 More...
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NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461
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G |
Aldh1a1 |
aldehyde dehydrogenase family 1, subfamily A1 |
increases expression |
ISO |
Streptozocin results in increased expression of ALDH1A1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr19:20,469,947...20,620,827
Ensembl chr19:20,470,079...20,620,829
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G |
Aldh1a3 |
aldehyde dehydrogenase family 1, subfamily A3 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of ALDH1A3 mRNA |
CTD |
PMID:33484791 |
|
NCBI chr 7:66,040,640...66,077,225
Ensembl chr 7:66,040,638...66,077,265
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G |
Aldh2 |
aldehyde dehydrogenase 2, mitochondrial |
increases expression decreases expression multiple interactions |
ISO |
Streptozocin results in increased expression of ALDH2 protein Streptozocin results in decreased expression of ALDH2 mRNA; Streptozocin results in decreased expression of ALDH2 protein Ethanol inhibits the reaction [Streptozocin results in decreased expression of ALDH2] |
CTD |
PMID:21136691 PMID:23500772 |
|
NCBI chr 5:121,704,090...121,731,887
Ensembl chr 5:121,704,090...121,731,887
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G |
Aldob |
aldolase B, fructose-bisphosphate |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of ALDOB protein Trientine inhibits the reaction [Streptozocin results in increased expression of ALDOB protein] |
CTD |
PMID:19634143 |
|
NCBI chr 4:49,535,993...49,549,546
Ensembl chr 4:49,535,995...49,549,546
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|
G |
Alkbh3 |
alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of ALKBH3 mRNA |
CTD |
PMID:20665664 |
|
NCBI chr 2:93,810,979...93,841,099
Ensembl chr 2:93,810,895...93,841,152
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|
G |
Alox5ap |
arachidonate 5-lipoxygenase activating protein |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of ALOX5AP mRNA |
CTD |
PMID:29127188 |
|
NCBI chr 5:149,201,814...149,224,963
Ensembl chr 5:149,201,577...149,224,963
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|
G |
Alpk1 |
alpha-kinase 1 |
increases response to substance multiple interactions |
ISO |
ALPK1 protein results in increased susceptibility to Streptozocin [ALPK1 protein results in increased susceptibility to Streptozocin] which results in decreased expression of PRKG2 mRNA; [ALPK1 protein results in increased susceptibility to Streptozocin] which results in increased expression of TGFB1 mRNA; [ALPK1 protein results in increased susceptibility to Streptozocin] which results in increased expression of TGFB1 protein; ALPK1 protein promotes the reaction [Streptozocin results in decreased secretion of INS1 protein]; ALPK1 protein promotes the reaction [Streptozocin results in increased abundance of Blood Glucose] |
CTD |
PMID:27542954 |
|
NCBI chr 3:127,460,367...127,574,195
Ensembl chr 3:127,463,959...127,574,176
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|
G |
Ambn |
ameloblastin |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of AMBN mRNA |
CTD |
PMID:33484791 |
|
NCBI chr 5:88,603,850...88,616,390
Ensembl chr 5:88,603,850...88,616,390
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|
G |
Amigo1 |
adhesion molecule with Ig like domain 1 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of AMIGO1 protein |
CTD |
PMID:32495657 |
|
NCBI chr 3:108,093,605...108,099,602
Ensembl chr 3:108,093,651...108,099,602
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|
G |
Amy2-ps1 |
amylase 2, pseudogene 1 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of AMY2-PS1 mRNA |
CTD |
PMID:33484791 |
|
NCBI chr 3:113,089,550...113,114,010
Ensembl chr 3:113,089,565...113,114,013
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G |
Angpt1 |
angiopoietin 1 |
increases expression decreases expression multiple interactions |
ISO |
Streptozocin results in increased expression of ANGPT1 mRNA; Streptozocin results in increased expression of ANGPT1 protein Streptozocin results in decreased expression of ANGPT1 mRNA baicalin inhibits the reaction [Streptozocin results in decreased expression of ANGPT1 mRNA] |
CTD |
PMID:15643138 PMID:19958114 PMID:34414639 |
|
NCBI chr15:42,288,063...42,540,373
Ensembl chr15:42,288,119...42,540,373
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|
G |
Angpt2 |
angiopoietin 2 |
multiple interactions increases expression |
ISO |
Enalapril inhibits the reaction [Streptozocin results in increased expression of ANGPT2 mRNA]; Simvastatin inhibits the reaction [Streptozocin results in increased expression of ANGPT2 protein] Streptozocin results in increased expression of ANGPT2 mRNA; Streptozocin results in increased expression of ANGPT2 protein |
CTD |
PMID:15643138 PMID:19958114 PMID:20821229 |
|
NCBI chr 8:18,740,279...18,791,578
Ensembl chr 8:18,740,279...18,791,578
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G |
Angptl4 |
angiopoietin-like 4 |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in decreased expression of ANGPTL4 mRNA |
CTD |
PMID:25905778 |
|
NCBI chr17:33,993,874...34,000,549
Ensembl chr17:33,992,724...34,000,804
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|
G |
Ankrd1 |
ankyrin repeat domain 1 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of ANKRD1 mRNA vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of ANKRD1 mRNA] |
CTD |
PMID:16684804 |
|
NCBI chr19:36,089,365...36,097,244
Ensembl chr19:36,089,361...36,097,499
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|
G |
Ankrd2 |
ankyrin repeat domain 2 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of ANKRD2 mRNA |
CTD |
PMID:33484791 |
|
NCBI chr19:42,024,358...42,033,550
Ensembl chr19:42,024,439...42,033,549
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G |
Anpep |
alanyl aminopeptidase, membrane |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of ANPEP protein Trientine inhibits the reaction [Streptozocin results in decreased expression of ANPEP protein] |
CTD |
PMID:19634143 |
|
NCBI chr 7:79,471,551...79,497,958
Ensembl chr 7:79,471,551...79,510,807
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|
G |
Anxa3 |
annexin A3 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of ANXA3 protein [resveratrol co-treated with Streptozocin] results in increased expression of ANXA3 mRNA; Trientine inhibits the reaction [Streptozocin results in increased expression of ANXA3 protein] |
CTD |
PMID:21136691 PMID:25905778 |
|
NCBI chr 5:96,941,257...96,993,825
Ensembl chr 5:96,941,198...96,993,825
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|
G |
Anxa5 |
annexin A5 |
decreases expression increases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of ANXA5 protein Streptozocin results in increased expression of ANXA5 protein Trientine inhibits the reaction [Streptozocin results in decreased expression of ANXA5 protein]; Trientine inhibits the reaction [Streptozocin results in increased expression of ANXA5 protein] |
CTD |
PMID:19634143 PMID:21136691 |
|
NCBI chr 3:36,503,072...36,530,036
Ensembl chr 3:36,503,072...36,530,043
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|
G |
Apex1 |
apurinic/apyrimidinic endonuclease 1 |
increases response to substance |
ISO |
APEX1 protein mutant form results in increased susceptibility to Streptozocin |
CTD |
PMID:19470598 |
|
NCBI chr14:51,162,406...51,164,645
Ensembl chr14:51,162,425...51,164,596
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G |
Apoa1 |
apolipoprotein A-I |
multiple interactions increases expression |
ISO |
Trientine inhibits the reaction [Streptozocin results in increased expression of APOA1 protein] |
CTD |
PMID:19634143 |
|
NCBI chr 9:46,139,928...46,141,767
Ensembl chr 9:46,139,878...46,141,764
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G |
Apoa4 |
apolipoprotein A-IV |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in decreased expression of APOA4 mRNA |
CTD |
PMID:25905778 |
|
NCBI chr 9:46,152,142...46,154,756
Ensembl chr 9:46,151,994...46,154,757
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G |
Apob |
apolipoprotein B |
multiple interactions |
ISO |
[[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of APOB mRNA |
CTD |
PMID:35786680 |
|
NCBI chr12:8,027,629...8,066,839
Ensembl chr12:8,027,648...8,066,835
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G |
Apoe |
apolipoprotein E |
increases expression multiple interactions |
ISO EXP |
Streptozocin results in increased expression of APOE mRNA vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of APOE mRNA] [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of ACACA mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of ACTA2 mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of ADGRE1 mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of CCL2 mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of CD36 mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of CD68 mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of COL3A1 mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of FASN mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of GPT protein; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of HSL mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of IGFBP1 mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of IGFBP1 protein; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of IL6 mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of LPL mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of LY6C1 mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of LY6G mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of PCK2 protein; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of PNPLA2 protein; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of PPARA mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of PPARA protein; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of PPARG mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of SREBF1 mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of TGFB1 mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of TNF mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the phosphorylation of GSK3B protein; [Streptozocin co-treated with APOE mutant form] results in increased abundance of Glucosamine; INS1 inhibits the reaction [[Streptozocin co-treated with APOE mutant form] results in increased abundance of Glucosamine]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of ACACA mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of ACTA2 mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of ADGRE1 mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of CCL2 mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of CD36 mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of CD68 mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of COL3A1 mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of CPT1A protein]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of FASN mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of GPT protein]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of IGFBP1 mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of IGFBP1 protein]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of IL6 mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of LPL mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of LY6C1 mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of LY6G mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of PCK2 protein]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of PNPLA2 protein]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of PPARA mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of PPARA protein]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of SREBF1 mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of TGFB1 mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of TNF mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the phosphorylation of GSK3B protein] |
CTD |
PMID:16380481 PMID:16684804 PMID:39047806 |
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NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113
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G |
App |
amyloid beta precursor protein |
multiple interactions increases expression |
ISO EXP |
Memantine inhibits the reaction [Streptozocin results in increased expression of APP protein modified form] Streptozocin results in increased expression of APP mRNA; Streptozocin results in increased expression of APP protein; Streptozocin results in increased expression of APP protein modified form 5-Methoxypsoralen inhibits the reaction [Streptozocin results in increased expression of APP protein modified form]; Alendronate inhibits the reaction [Streptozocin results in increased expression of APP protein]; Donepezil inhibits the reaction [Streptozocin results in increased expression of APP protein]; Tadalafil inhibits the reaction [Streptozocin results in increased expression of APP protein modified form] |
CTD |
PMID:21069392 PMID:21290839 PMID:30481507 PMID:34428446 |
|
NCBI chr16:84,751,236...84,972,187
Ensembl chr16:84,746,573...84,970,654
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G |
Aqp1 |
aquaporin 1 |
multiple interactions decreases expression |
ISO |
Trientine inhibits the reaction [Streptozocin results in decreased expression of AQP1 protein] |
CTD |
PMID:19634143 |
|
NCBI chr 6:55,313,284...55,325,540
Ensembl chr 6:55,313,417...55,325,540
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|
G |
Aqp7 |
aquaporin 7 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of AQP7 mRNA vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of AQP7 mRNA] |
CTD |
PMID:16684804 |
|
NCBI chr 4:41,033,074...41,048,237
Ensembl chr 4:41,033,074...41,048,139
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G |
Aqp9 |
aquaporin 9 |
increases expression |
ISO |
Streptozocin results in increased expression of AQP9 protein |
CTD |
PMID:22114114 |
|
NCBI chr 9:71,017,941...71,075,170
Ensembl chr 9:71,017,941...71,075,964
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G |
Arg1 |
arginase, liver |
multiple interactions increases expression decreases expression increases activity |
EXP ISO |
[NTN1 protein co-treated with Streptozocin] results in increased expression of ARG1 protein; AM6545 inhibits the reaction [Streptozocin results in decreased expression of ARG1 mRNA]; ARG1 gene mutant form inhibits the reaction [Streptozocin results in increased expression of GLB1 protein]; Perindopril inhibits the reaction [AM6545 inhibits the reaction [Streptozocin results in decreased expression of ARG1 mRNA]] Streptozocin results in increased expression of ARG1 protein Streptozocin results in increased activity of ARG1 protein |
CTD |
PMID:29059224 PMID:29673160 PMID:30184259 PMID:34039237 |
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NCBI chr10:24,791,105...24,803,368
Ensembl chr10:24,791,119...24,803,382
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|
G |
Arhgap9 |
Rho GTPase activating protein 9 |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of ARHGAP9 mRNA |
CTD |
PMID:25905778 |
|
NCBI chr10:127,157,829...127,165,816
Ensembl chr10:127,157,833...127,165,812
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|
G |
Asns |
asparagine synthetase |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of ASNS mRNA |
CTD |
PMID:25905778 |
|
NCBI chr 6:7,675,169...7,693,209
Ensembl chr 6:7,675,169...7,693,254
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G |
Atf2 |
activating transcription factor 2 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of ATF2 protein resveratrol inhibits the reaction [Streptozocin results in increased expression of ATF2 protein] |
CTD |
PMID:26499206 |
|
NCBI chr 2:73,646,853...73,723,094
Ensembl chr 2:73,646,853...73,722,983
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G |
Atf3 |
activating transcription factor 3 |
multiple interactions |
EXP |
[Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of ATF3 mRNA]; [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of ATF3 protein]; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of ATF3 mRNA; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of ATF3 protein |
CTD |
PMID:38282657 |
|
NCBI chr 1:190,902,493...190,915,530
Ensembl chr 1:190,902,493...190,950,236
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|
G |
Atf4 |
activating transcription factor 4 |
multiple interactions increases expression increases phosphorylation |
EXP ISO |
[Dietary Fats co-treated with Streptozocin] results in increased expression of ATF4 mRNA; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of ATF4 mRNA]; sulforaphane inhibits the reaction [Streptozocin results in increased expression of ATF4 protein] Streptozocin results in increased phosphorylation of ATF4 protein 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased phosphorylation of ATF4 protein] |
CTD |
PMID:24967692 PMID:30980806 PMID:33812996 |
|
NCBI chr15:80,139,385...80,141,746
Ensembl chr15:80,139,385...80,141,742
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|
G |
Atf5 |
activating transcription factor 5 |
decreases expression |
ISO |
Streptozocin results in decreased expression of ATF5 mRNA |
CTD |
PMID:25905778 |
|
NCBI chr 7:44,461,680...44,466,082
Ensembl chr 7:44,461,680...44,466,082
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G |
Atf6 |
activating transcription factor 6 |
multiple interactions increases cleavage increases expression |
ISO EXP |
4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased cleavage of ATF6 protein]; [Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of ATF6 protein; Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of ATF6 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of ATF6 protein] [Dietary Fats co-treated with Streptozocin] results in increased expression of ATF6 mRNA; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of ATF6 mRNA] streptozocin increases expression of Atf6 protein in heart |
CTD RGD |
PMID:30980806 PMID:33812996 PMID:34801538 PMID:36044268 |
RGD:156430337 |
NCBI chr 1:170,532,026...170,696,414
Ensembl chr 1:170,532,243...170,695,340
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|
G |
Atg12 |
autophagy related 12 |
increases expression |
EXP |
Streptozocin results in increased expression of ATG12 mRNA |
CTD |
PMID:24889822 |
|
NCBI chr18:46,865,484...46,874,683
Ensembl chr18:46,863,211...46,874,647
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|
G |
Atg5 |
autophagy related 5 |
increases expression multiple interactions |
EXP ISO |
Streptozocin results in increased expression of ATG5 mRNA [[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in decreased expression of ATG5 mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of ATG5 mRNA Streptozocin results in increased expression of ATG5 protein |
CTD |
PMID:24889822 PMID:35786680 PMID:38706688 |
|
NCBI chr10:44,144,325...44,240,295
Ensembl chr10:44,144,354...44,240,287
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G |
Atox1 |
antioxidant 1 copper chaperone |
decreases expression |
ISO |
Streptozocin results in decreased expression of ATOX1 protein |
CTD |
PMID:24927960 |
|
NCBI chr11:55,337,463...55,352,034
Ensembl chr11:55,337,467...55,352,065
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|
G |
Atp2a2 |
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 |
decreases activity multiple interactions decreases expression |
ISO EXP |
Streptozocin results in decreased activity of ATP2A2 protein [bisphenol A co-treated with Streptozocin] results in decreased expression of ATP2A2 mRNA; [Ethinyl Estradiol co-treated with Streptozocin] results in decreased expression of ATP2A2 mRNA; [octylphenol co-treated with Streptozocin] results in decreased expression of ATP2A2 mRNA Streptozocin results in decreased expression of ATP2A2 mRNA Triterpenes inhibits the reaction [Streptozocin results in decreased expression of ATP2A2 mRNA]; Triterpenes inhibits the reaction [Streptozocin results in decreased expression of ATP2A2 protein] Streptozocin results in decreased expression of ATP2A2 mRNA; Streptozocin results in decreased expression of ATP2A2 protein |
CTD |
PMID:16685413 PMID:19000375 PMID:29935216 |
|
NCBI chr 5:122,591,576...122,640,288
Ensembl chr 5:122,591,576...122,640,288
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G |
Atp2a3 |
ATPase, Ca++ transporting, ubiquitous |
multiple interactions |
EXP |
[Streptozocin co-treated with bisphenol A] results in decreased expression of ATP2A3 mRNA; [Streptozocin co-treated with octylphenol] results in decreased expression of ATP2A3 mRNA |
CTD |
PMID:29935216 |
|
NCBI chr11:72,851,995...72,883,869
Ensembl chr11:72,851,995...72,883,870
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G |
Atp2b1 |
ATPase, Ca++ transporting, plasma membrane 1 |
multiple interactions increases expression |
EXP |
[Streptozocin co-treated with bisphenol A] results in increased expression of ATP2B1 mRNA; [Streptozocin co-treated with octylphenol] results in increased expression of ATP2B1 mRNA Streptozocin results in increased expression of ATP2B1 mRNA |
CTD |
PMID:29935216 |
|
NCBI chr10:98,750,243...98,862,005
Ensembl chr10:98,750,268...98,862,005
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|
G |
Atp5f1a |
ATP synthase F1 subunit alpha |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of ATP5F1A protein Trientine inhibits the reaction [Streptozocin results in increased expression of ATP5F1A protein] |
CTD |
PMID:21136691 |
|
NCBI chr18:77,861,468...77,870,569
Ensembl chr18:77,861,429...77,870,569
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G |
Atp5f1b |
ATP synthase F1 subunit beta |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of ATP5F1B protein Trientine inhibits the reaction [Streptozocin results in increased expression of ATP5F1B protein] |
CTD |
PMID:21136691 |
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NCBI chr10:127,919,176...127,926,257
Ensembl chr10:127,919,142...127,926,260
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G |
Atp5mf |
ATP synthase membrane subunit f |
increases expression multiple interactions affects expression |
ISO EXP |
Streptozocin results in increased expression of ATP5MF protein Trientine inhibits the reaction [Streptozocin results in increased expression of ATP5MF protein] Streptozocin affects the expression of ATP5MF mRNA |
CTD |
PMID:18583417 PMID:19634143 |
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NCBI chr 5:145,120,514...145,128,351
Ensembl chr 5:145,120,508...145,128,872
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G |
Atp5po |
ATP synthase peripheral stalk subunit OSCP |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of ATP5PO protein Trientine inhibits the reaction [Streptozocin results in increased expression of ATP5PO protein] |
CTD |
PMID:19634143 |
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NCBI chr16:91,722,111...91,728,518
Ensembl chr16:91,722,102...91,728,575 Ensembl chr16:91,722,102...91,728,575
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G |
Atp6ap2 |
ATPase, H+ transporting, lysosomal accessory protein 2 |
multiple interactions increases expression |
ISO |
(3,4-dihydroxyphenylamino)-2-imidazoline inhibits the reaction [Streptozocin results in increased expression of ATP6AP2 mRNA]; (3,4-dihydroxyphenylamino)-2-imidazoline inhibits the reaction [Streptozocin results in increased expression of ATP6AP2 protein]; Valsartan inhibits the reaction [Streptozocin results in increased expression of ATP6AP2 mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of ATP6AP2 protein] Streptozocin results in increased expression of ATP6AP2 mRNA; Streptozocin results in increased expression of ATP6AP2 protein |
CTD |
PMID:18192338 |
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NCBI chr X:12,453,998...12,483,290
Ensembl chr X:12,454,040...12,483,288
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G |
Atp7a |
ATPase, copper transporting, alpha polypeptide |
multiple interactions decreases expression |
EXP |
ATP7A gene mutant form promotes the reaction [Streptozocin results in increased chemical synthesis of Superoxides]; ATP7A protein inhibits the reaction [Streptozocin results in increased chemical synthesis of Superoxides]; INS protein inhibits the reaction [Streptozocin results in decreased expression of ATP7A protein] |
CTD |
PMID:23884884 |
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NCBI chr X:105,070,830...105,171,766
Ensembl chr X:105,070,882...105,168,532
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G |
Atp7b |
ATPase, copper transporting, beta polypeptide |
decreases expression |
ISO |
Streptozocin results in decreased expression of ATP7B protein |
CTD |
PMID:24927960 |
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NCBI chr 8:22,482,799...22,550,347
Ensembl chr 8:22,482,801...22,550,321
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G |
Avp |
arginine vasopressin |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in increased expression of AVP mRNA; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in increased expression of AVP mRNA] |
CTD |
PMID:32303808 |
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NCBI chr 2:130,422,540...130,424,508
Ensembl chr 2:130,422,540...130,424,474
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G |
Axl |
AXL receptor tyrosine kinase |
increases expression |
ISO |
Streptozocin results in increased expression of AXL protein |
CTD |
PMID:12644472 |
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NCBI chr 7:25,455,925...25,488,502
Ensembl chr 7:25,456,698...25,488,130
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G |
B2m |
beta-2 microglobulin |
multiple interactions increases expression |
ISO EXP |
diphenyldiselenide inhibits the reaction [Streptozocin results in increased activity of B2M protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of B2M protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of B2M protein] Metformin inhibits the reaction [Streptozocin results in increased expression of B2M protein]; phillyrin inhibits the reaction [Streptozocin results in increased expression of B2M protein] |
CTD |
PMID:33639173 PMID:34649470 |
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NCBI chr 2:121,978,168...121,983,563
Ensembl chr 2:121,978,167...121,983,564
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G |
B3galnt1 |
UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 1 |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of B3GALNT1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 3:69,481,252...69,506,305
Ensembl chr 3:69,481,491...69,506,293
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G |
Baat |
bile acid-Coenzyme A: amino acid N-acyltransferase |
multiple interactions |
EXP |
[Dietary Fats co-treated with Streptozocin] results in decreased expression of BAAT mRNA |
CTD |
PMID:29382564 |
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NCBI chr 4:49,489,416...49,507,915
Ensembl chr 4:49,489,422...49,506,557
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G |
Bace1 |
beta-site APP cleaving enzyme 1 |
multiple interactions increases expression |
EXP |
Alendronate inhibits the reaction [Streptozocin results in increased expression of BACE1 protein]; Donepezil inhibits the reaction [Streptozocin results in increased expression of BACE1 protein] |
CTD |
PMID:30481507 |
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NCBI chr 9:45,749,878...45,775,694
Ensembl chr 9:45,749,878...45,775,697
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G |
Bad |
BCL2-associated agonist of cell death |
multiple interactions decreases expression increases expression |
ISO |
Anthocyanins inhibits the reaction [Streptozocin results in decreased expression of BAD protein modified form]; Anthocyanins inhibits the reaction [Streptozocin results in increased expression of BAD protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased expression of BAD protein]; Streptozocin results in increased phosphorylation of and results in decreased activity of BAD protein Streptozocin results in decreased expression of BAD protein; Streptozocin results in decreased expression of BAD protein modified form |
CTD |
PMID:15976052 PMID:19682444 PMID:28856781 |
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NCBI chr19:6,919,229...6,929,273
Ensembl chr19:6,919,229...6,929,267
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G |
Bak1 |
BCL2-antagonist/killer 1 |
multiple interactions increases expression |
ISO |
Anthocyanins inhibits the reaction [Streptozocin results in increased expression of BAK1 protein] |
CTD |
PMID:28856781 |
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NCBI chr17:27,238,786...27,247,601
Ensembl chr17:27,238,784...27,247,983
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G |
Bax |
BCL2-associated X protein |
multiple interactions increases expression affects expression |
EXP ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of BAX mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of BAX protein; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of BAX protein]; IGF1 protein inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of BAX protein]; montelukast inhibits the reaction [Streptozocin results in increased expression of BAX protein]; phillyrin inhibits the reaction [Streptozocin results in increased expression of BAX protein]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of BAX mRNA]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of BAX protein]; sulforaphane inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Valsartan inhibits the reaction [Streptozocin results in increased expression of BAX protein] Streptozocin results in increased expression of BAX; Streptozocin results in increased expression of BAX mRNA; Streptozocin results in increased expression of BAX protein 2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BAX protein]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Streptozocin results in increased expression of BAX protein]; 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of BAX protein]; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of BAX protein; [Streptozocin co-treated with Isoproterenol] affects the expression of BAX protein; Angiotensin-Converting Enzyme Inhibitors inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Ascorbic Acid inhibits the reaction [Streptozocin results in increased expression of BAX protein]; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of BAX protein]; bisphenol A diglycidyl ether inhibits the reaction [Calcitriol inhibits the reaction [Streptozocin results in increased expression of BAX protein]]; Calcitriol inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Curcumin inhibits the reaction [Streptozocin affects the expression of BAX protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; Diazoxide inhibits the reaction [Streptozocin results in increased expression of BAX protein]; fasudil inhibits the reaction [Streptozocin results in increased expression of BAX protein]; ferulic acid inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of BAX protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Hesperidin inhibits the reaction [2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BAX protein]]; Hesperidin inhibits the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BAX protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; Metformin inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; morin inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; Organoselenium Compounds inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Pentoxifylline inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Phosphocreatine inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Phycocyanin inhibits the reaction [Streptozocin results in increased expression of BAX protein]; piperlongumine inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of BAX]; Rivastigmine inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Sildenafil Citrate inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; Sildenafil Citrate promotes the reaction [Tadalafil inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]]; Streptozocin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of BAX protein]; Tadalafil inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; Tadalafil promotes the reaction [Sildenafil Citrate inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]]; Testosterone inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; Testosterone promotes the reaction [Sildenafil Citrate inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]]; Testosterone promotes the reaction [Sildenafil Citrate promotes the reaction [Tadalafil inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]]]; Testosterone promotes the reaction [Tadalafil inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]]; Testosterone promotes the reaction [Tadalafil promotes the reaction [Sildenafil Citrate inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]]]; Wortmannin inhibits the reaction [Phycocyanin inhibits the reaction [Streptozocin results in increased expression of BAX protein]]; Zinc inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; Zinc inhibits the reaction [Streptozocin results in increased expression of BAX protein] |
CTD |
PMID:11375343 PMID:18758938 PMID:19931367 PMID:20574430 PMID:20650802 PMID:22429817 PMID:23267840 PMID:24954035 PMID:24967692 PMID:25191525 PMID:25301743 PMID:25541178 PMID:27702591 PMID:29266779 PMID:29953732 PMID:30611788 PMID:30980806 PMID:31009641 PMID:31029786 PMID:31323227 PMID:32805344 PMID:33484791 PMID:33724628 PMID:34455488 PMID:34610774 PMID:34649470 PMID:35414346 PMID:36510688 PMID:37431890 More...
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NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
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G |
Baz1b |
bromodomain adjacent to zinc finger domain, 1B |
affects expression |
EXP |
Streptozocin affects the expression of BAZ1B mRNA |
CTD |
PMID:26073000 |
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NCBI chr 5:135,214,094...135,274,985
Ensembl chr 5:135,216,118...135,274,983
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G |
Bbox1 |
gamma-butyrobetaine hydroxylase 1 |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in decreased expression of BBOX1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 2:110,094,401...110,145,158
Ensembl chr 2:110,093,042...110,144,905
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G |
Bche |
butyrylcholinesterase |
multiple interactions increases activity |
EXP |
Acetylcysteine inhibits the reaction [Streptozocin results in increased activity of BCHE protein] |
CTD |
PMID:27087133 PMID:30481507 |
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NCBI chr 3:73,543,138...73,615,767
Ensembl chr 3:73,543,141...73,615,748
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G |
Bckdha |
branched chain ketoacid dehydrogenase E1, alpha polypeptide |
affects expression |
EXP |
Streptozocin affects the expression of BCKDHA mRNA |
CTD |
PMID:18583417 |
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NCBI chr 7:25,329,371...25,358,178
Ensembl chr 7:25,329,371...25,358,406
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G |
Bcl2 |
B cell leukemia/lymphoma 2 |
increases expression decreases expression multiple interactions affects expression |
ISO EXP |
Streptozocin results in increased expression of BCL2 protein Streptozocin results in decreased expression of BCL2 mRNA; Streptozocin results in decreased expression of BCL2 protein [Diethylhexyl Phthalate co-treated with Streptozocin co-treated with Dietary Fats] results in decreased expression of BCL2 protein; [Streptozocin co-treated with arachidonyl-2-chloroethylamide] results in increased expression of BCL2 protein; [Streptozocin co-treated with bisphenol A] results in increased expression of BCL2 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of BCL2 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of BCL2 protein; [Streptozocin co-treated with Ethinyl Estradiol] results in increased expression of BCL2 mRNA; [Streptozocin co-treated with octylphenol] results in increased expression of BCL2 mRNA; AM 251 inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; bisphenol A promotes the reaction [Streptozocin results in decreased expression of BCL2 protein]; CEBPB protein inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; CNR1 protein promotes the reaction [Streptozocin results in decreased expression of BCL2 protein]; Ethinyl Estradiol promotes the reaction [Streptozocin results in decreased expression of BCL2 protein]; Metformin inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; montelukast inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; octylphenol promotes the reaction [Streptozocin results in decreased expression of BCL2 protein]; phillyrin inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of BCL2 mRNA]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of BCL2 protein]; Streptozocin inhibits the reaction [Cisplatin results in increased expression of BCL2 protein]; Valsartan inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein] 2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BCL2 protein]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of BCL2 protein; [Rolipram co-treated with Pentoxifylline] inhibits the reaction [Streptozocin results in increased expression of BCL2 protein]; [Streptozocin co-treated with Arsenic] results in decreased expression of BCL2 mRNA; [Streptozocin co-treated with Cadmium] results in decreased expression of BCL2 mRNA; [Streptozocin co-treated with Isoproterenol] affects the expression of BCL2 protein; [Streptozocin co-treated with Lead co-treated with Manganese co-treated with Cadmium co-treated with Arsenic] results in decreased expression of BCL2 mRNA; [Streptozocin co-treated with Lead] results in decreased expression of BCL2 mRNA; [Streptozocin co-treated with Manganese] results in decreased expression of BCL2 mRNA; Angiotensin-Converting Enzyme Inhibitors inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Anthocyanins inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased expression of BCL2 protein]; Ascorbic Acid inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of BCL2 protein]; bisphenol A diglycidyl ether inhibits the reaction [Calcitriol inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]]; Calcitriol inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Curcumin inhibits the reaction [Streptozocin affects the expression of BCL2 protein]; dapagliflozin inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]; Diazoxide inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; fasudil inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of BCL2 protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Hesperidin inhibits the reaction [2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BCL2 protein]]; Hesperidin inhibits the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BCL2 protein]; IGF2R protein modified form promotes the reaction [Streptozocin results in decreased expression of BCL2 protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of BCL2 mRNA]; morin inhibits the reaction [Streptozocin results in increased expression of BCL2 mRNA]; Organoselenium Compounds inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Pentoxifylline inhibits the reaction [Streptozocin results in increased expression of BCL2 protein]; Phosphocreatine inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; piperlongumine inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Propofol inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Rivastigmine inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Sildenafil Citrate inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]; Sildenafil Citrate promotes the reaction [Tadalafil inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]]; Streptozocin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased expression of BCL2 protein]; Streptozocin promotes the reaction [IGF2R protein modified form results in decreased expression of BCL2 protein modified form]; Tadalafil inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]; Tadalafil promotes the reaction [Sildenafil Citrate inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]]; Testosterone inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]; Testosterone promotes the reaction [Sildenafil Citrate inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]]; Testosterone promotes the reaction [Sildenafil Citrate promotes the reaction [Tadalafil inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]]]; Testosterone promotes the reaction [Tadalafil inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]]; Testosterone promotes the reaction [Tadalafil promotes the reaction [Sildenafil Citrate inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]]]; Zinc inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]; Zinc inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein] |
CTD |
PMID:15056984 PMID:15587404 PMID:15976052 PMID:16909474 PMID:18758938 PMID:19682444 PMID:20574430 PMID:20650802 PMID:22429817 PMID:24781736 PMID:24810525 PMID:24954035 PMID:25301743 PMID:25541178 PMID:25665769 PMID:26967640 PMID:27702591 PMID:28856781 PMID:29266779 PMID:29953732 PMID:30607903 PMID:30611788 PMID:31009641 PMID:31323227 PMID:32246071 PMID:32805344 PMID:33484791 PMID:33724628 PMID:34455488 PMID:34610774 PMID:34649470 PMID:35414346 PMID:36462176 PMID:36510688 PMID:37352119 PMID:37431890 More...
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NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
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G |
Bcl2a1b |
B cell leukemia/lymphoma 2 related protein A1b |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of BCL2A1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 9:89,081,326...89,089,891
Ensembl chr 9:89,081,262...89,089,880
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G |
Bcl2l1 |
BCL2-like 1 |
increases expression multiple interactions decreases expression |
ISO EXP |
Streptozocin results in increased expression of BCL2L1 protein Anthocyanins inhibits the reaction [Streptozocin results in decreased expression of BCL2L1 protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased expression of BCL2L1 protein]; Ascorbic Acid inhibits the reaction [Streptozocin results in decreased expression of BCL2L1 protein]; cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of BCL2L1 protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of BCL2L1 mRNA]; morin inhibits the reaction [Streptozocin results in increased expression of BCL2L1 mRNA]; tin mesoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of BCL2L1 protein]] Streptozocin results in decreased expression of BCL2L1 mRNA; Streptozocin results in decreased expression of BCL2L1 protein |
CTD |
PMID:15976052 PMID:16595661 PMID:18758938 PMID:19682444 PMID:24781736 PMID:28856781 PMID:35414346 More...
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NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648
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G |
Bcl2l11 |
BCL2 like 11 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of BCL2L11 mRNA Chlorpyrifos promotes the reaction [Streptozocin results in increased expression of BCL2L11 mRNA] |
CTD |
PMID:33524429 |
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NCBI chr 2:127,967,958...128,004,467
Ensembl chr 2:127,967,958...128,004,467
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G |
Bcl3 |
B cell leukemia/lymphoma 3 |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of BCL3 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 7:19,542,387...19,556,691
Ensembl chr 7:19,542,387...19,556,695
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G |
Bdh1 |
3-hydroxybutyrate dehydrogenase, type 1 |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in decreased expression of BDH1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr16:31,241,115...31,277,719
Ensembl chr16:31,241,098...31,277,719
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G |
Bdkrb1 |
bradykinin receptor, beta 1 |
increases expression multiple interactions |
EXP ISO |
Streptozocin results in increased expression of BDKRB1 mRNA [HOE 140, desArg(10)- binds to and results in decreased activity of BDKRB1 protein] which results in decreased susceptibility to Streptozocin |
CTD |
PMID:17989505 PMID:19516248 |
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NCBI chr12:105,570,350...105,571,770
Ensembl chr12:105,569,344...105,571,687
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G |
Bdkrb2 |
bradykinin receptor, beta 2 |
increases expression multiple interactions |
EXP ISO |
Streptozocin results in increased expression of BDKRB2 mRNA [icatibant binds to and results in decreased activity of BDKRB2 protein] which results in decreased susceptibility to Streptozocin |
CTD |
PMID:17989505 PMID:19516248 |
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NCBI chr12:105,529,431...105,561,503
Ensembl chr12:105,529,485...105,561,496
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G |
Bdnf |
brain derived neurotrophic factor |
multiple interactions decreases expression |
ISO EXP |
Metformin inhibits the reaction [Streptozocin results in increased expression of BDNF mRNA]; morin inhibits the reaction [Streptozocin results in increased expression of BDNF mRNA]; Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of BDNF protein]; Rivastigmine inhibits the reaction [Streptozocin results in decreased expression of BDNF protein]; Vitamin B 12 inhibits the reaction [Streptozocin results in decreased expression of BDNF protein]; Wortmannin inhibits the reaction [Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of BDNF protein]] Streptozocin results in decreased expression of BDNF mRNA; Streptozocin results in decreased expression of BDNF protein 5-Methoxypsoralen inhibits the reaction [Streptozocin results in decreased expression of BDNF protein]; Tadalafil inhibits the reaction [Streptozocin results in decreased expression of BDNF protein] |
CTD |
PMID:32805344 PMID:34428446 PMID:35414346 PMID:38049026 |
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NCBI chr 2:109,505,045...109,557,388
Ensembl chr 2:109,505,045...109,557,352
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G |
Becn1 |
beclin 1, autophagy related |
increases expression decreases expression multiple interactions |
EXP ISO |
Streptozocin results in increased expression of BECN1 mRNA; Streptozocin results in increased expression of BECN1 protein Streptozocin results in decreased expression of BECN1 protein; Streptozocin results in decreased expression of BECN1 protein modified form 5-Methoxypsoralen inhibits the reaction [Streptozocin results in decreased expression of BECN1 protein modified form]; HU 308 inhibits the reaction [Streptozocin results in decreased expression of BECN1 protein]; Tadalafil inhibits the reaction [Streptozocin results in decreased expression of BECN1 protein modified form] [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of BECN1 mRNA; dapagliflozin affects the reaction [Streptozocin results in decreased expression of BECN1 mRNA] |
CTD |
PMID:24889822 PMID:30459625 PMID:34428446 PMID:35786680 PMID:37352119 |
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NCBI chr11:101,179,084...101,193,112
Ensembl chr11:101,176,778...101,193,112
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G |
Bglap |
bone gamma carboxyglutamate protein |
decreases expression multiple interactions |
ISO EXP |
Streptozocin results in decreased expression of BGLAP mRNA; Streptozocin results in decreased expression of BGLAP protein [Dietary Fats co-treated with Streptozocin] results in decreased expression of BGLAP protein modified form; Warfarin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of BGLAP protein modified form] [Streptozocin co-treated with Dietary Fats] results in decreased expression of BGLAP protein; Calcitriol inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of BGLAP protein] |
CTD |
PMID:25617479 PMID:27488359 PMID:33450223 |
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NCBI chr 3:88,290,802...88,291,773
Ensembl chr 3:88,290,808...88,291,771
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G |
Bhmt |
betaine-homocysteine methyltransferase |
increases activity increases expression multiple interactions |
ISO EXP |
Streptozocin results in increased activity of BHMT protein Streptozocin results in increased expression of BHMT mRNA [Streptozocin co-treated with Dietary Fats] affects the expression of BHMT mRNA |
CTD |
PMID:16835399 PMID:29127188 |
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NCBI chr13:93,753,399...93,774,266
Ensembl chr13:93,753,183...93,774,469
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G |
Bmal1 |
basic helix-loop-helix ARNT like 1 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of BMAL1 mRNA |
CTD |
PMID:29127188 |
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NCBI chr 7:112,777,820...112,913,333
Ensembl chr 7:112,806,672...112,913,333
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G |
Bmp6 |
bone morphogenetic protein 6 |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of BMP6 mRNA esculetin inhibits the reaction [Streptozocin results in decreased expression of BMP6 mRNA] |
CTD |
PMID:21450970 |
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NCBI chr13:38,529,098...38,684,283
Ensembl chr13:38,529,083...38,684,278
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G |
Bmp7 |
bone morphogenetic protein 7 |
increases expression affects expression |
ISO |
Streptozocin results in increased expression of BMP7 protein Streptozocin affects the expression of BMP7 mRNA |
CTD |
PMID:17437042 |
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NCBI chr 2:172,709,805...172,782,114
Ensembl chr 2:172,709,805...172,782,114
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G |
C1qa |
complement component 1, q subcomponent, alpha polypeptide |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of C1QA mRNA |
CTD |
PMID:25905778 |
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NCBI chr 4:136,623,227...136,626,155
Ensembl chr 4:136,623,228...136,626,114
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G |
C1qb |
complement component 1, q subcomponent, beta polypeptide |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of C1QB mRNA [resveratrol co-treated with Streptozocin] results in increased expression of C1QB mRNA; vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of C1QB mRNA] |
CTD |
PMID:16684804 PMID:25905778 |
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NCBI chr 4:136,607,437...136,613,511
Ensembl chr 4:136,607,440...136,613,498
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G |
C1qc |
complement component 1, q subcomponent, C chain |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of C1QC mRNA |
CTD |
PMID:25905778 |
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NCBI chr 4:136,617,115...136,620,225
Ensembl chr 4:136,617,115...136,620,376
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G |
C4b |
complement C4B (Chido blood group) |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of C4B mRNA vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of C4B mRNA] |
CTD |
PMID:16684804 |
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NCBI chr17:34,947,249...34,962,876
Ensembl chr17:34,947,354...34,962,856
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G |
Cacna1b |
calcium channel, voltage-dependent, N type, alpha 1B subunit |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of CACNA1B mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CACNA1B mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 2:24,493,872...24,653,210
Ensembl chr 2:24,493,899...24,653,164
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G |
Cacna1c |
calcium channel, voltage-dependent, L type, alpha 1C subunit |
multiple interactions increases expression |
EXP |
[bisphenol A co-treated with Streptozocin] results in decreased expression of CACNA1C mRNA; [octylphenol co-treated with Streptozocin] results in decreased expression of CACNA1C mRNA Streptozocin results in increased expression of CACNA1C mRNA |
CTD |
PMID:29935216 |
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NCBI chr 6:118,564,201...119,174,345
Ensembl chr 6:118,564,201...119,173,851
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G |
Cacna1s |
calcium channel, voltage-dependent, L type, alpha 1S subunit |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of CACNA1S mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CACNA1S mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 1:135,980,549...136,047,268
Ensembl chr 1:135,980,488...136,047,560
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G |
Calca |
calcitonin/calcitonin-related polypeptide, alpha |
multiple interactions decreases expression |
ISO |
Botulinum Toxins, Type A inhibits the reaction [Streptozocin results in decreased expression of CALCA protein]; capsazepine inhibits the reaction [Streptozocin results in decreased expression of CALCA protein]; RN 1734 inhibits the reaction [Streptozocin results in decreased expression of CALCA protein]; U 0126 inhibits the reaction [Streptozocin results in decreased expression of CALCA protein] |
CTD |
PMID:30583000 |
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NCBI chr 7:114,225,223...114,236,145
Ensembl chr 7:114,230,713...114,235,592
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G |
Calm1 |
calmodulin 1 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in increased expression of CALM1 protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in increased expression of CALM1 protein] |
CTD |
PMID:32303808 |
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NCBI chr12:100,165,694...100,176,083
Ensembl chr12:100,165,694...100,176,073
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G |
Calm3 |
calmodulin 3 |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of CALM3 protein Trientine inhibits the reaction [Streptozocin results in decreased expression of CALM3 protein] |
CTD |
PMID:19634143 |
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NCBI chr 7:16,649,304...16,657,957
Ensembl chr 7:16,649,304...16,658,039
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G |
Calr |
calreticulin |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of CALR protein Trientine inhibits the reaction [Streptozocin results in decreased expression of CALR protein] |
CTD |
PMID:19634143 |
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NCBI chr 8:85,568,717...85,573,560
Ensembl chr 8:85,568,479...85,573,563
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G |
Camk2a |
calcium/calmodulin-dependent protein kinase II alpha |
multiple interactions decreases expression |
EXP ISO |
myristoylated autocamtide-2-related inhibitory peptide inhibits the reaction [Streptozocin results in increased phosphorylation of CAMK2A protein]; resveratrol inhibits the reaction [Streptozocin results in increased expression of and results in increased phosphorylation of and results in increased activity of CAMK2A protein]; Streptozocin results in increased expression of and results in increased phosphorylation of and results in increased activity of CAMK2A protein Ibuprofen inhibits the reaction [Streptozocin results in decreased expression of CAMK2A mRNA]; Ibuprofen inhibits the reaction [Streptozocin results in decreased expression of CAMK2A protein]; Memantine inhibits the reaction [Streptozocin results in decreased expression of CAMK2A mRNA]; Memantine inhibits the reaction [Streptozocin results in decreased expression of CAMK2A protein] Streptozocin results in decreased expression of CAMK2A mRNA; Streptozocin results in decreased expression of CAMK2A protein |
CTD |
PMID:20424226 PMID:24333387 |
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NCBI chr18:61,058,704...61,121,224
Ensembl chr18:61,058,690...61,121,224
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G |
Camp |
cathelicidin antimicrobial peptide |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of CAMP mRNA |
CTD |
PMID:33484791 |
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NCBI chr 9:109,676,445...109,678,524
Ensembl chr 9:109,676,447...109,678,685
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G |
Canx |
calnexin |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of CANX protein; Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of CANX protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of CANX protein] |
CTD |
PMID:34801538 |
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NCBI chr11:50,184,784...50,216,500
Ensembl chr11:50,184,788...50,216,500
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G |
Capg |
capping actin protein, gelsolin like |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of CAPG mRNA |
CTD |
PMID:25905778 |
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NCBI chr 6:72,515,265...72,539,966
Ensembl chr 6:72,521,374...72,539,966
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G |
Capn8 |
calpain 8 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of CAPN8 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CAPN8 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 1:182,392,314...182,462,021
Ensembl chr 1:182,392,572...182,459,917
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G |
Car3 |
carbonic anhydrase 3 |
multiple interactions decreases expression |
ISO |
[resveratrol co-treated with Streptozocin] results in decreased expression of CAR3 mRNA Streptozocin results in decreased expression of CAR3 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 3:14,928,598...14,937,441
Ensembl chr 3:14,928,572...14,937,583
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G |
Cartpt |
CART prepropeptide |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of CARTPT mRNA GHRL protein promotes the reaction [Streptozocin results in decreased expression of CARTPT mRNA] |
CTD |
PMID:20219977 |
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NCBI chr13:100,034,991...100,037,191
Ensembl chr13:100,034,997...100,037,599
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G |
Casp1 |
caspase 1 |
multiple interactions increases expression |
ISO EXP |
[Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased cleavage of CASP1 protein]; [Streptozocin co-treated with Dietary Fats] results in increased cleavage of CASP1 protein; Allopurinol inhibits the reaction [Streptozocin results in increased expression of CASP1 mRNA]; Allopurinol inhibits the reaction [Streptozocin results in increased expression of CASP1 protein]; Dimethyl Fumarate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased cleavage of CASP1 protein]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased cleavage of CASP1 protein]; Insulin promotes the reaction [Ozone inhibits the reaction [Streptozocin results in increased expression of CASP1 mRNA]]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased cleavage of CASP1 protein]; Ozone inhibits the reaction [Streptozocin results in increased expression of CASP1 mRNA]; palbinone inhibits the reaction [Streptozocin results in increased expression of and results in increased cleavage of CASP1 protein]; Quercetin inhibits the reaction [Streptozocin results in increased expression of CASP1 mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of CASP1 protein]; scutellarin inhibits the reaction [Streptozocin results in increased expression of CASP1 mRNA]; Streptozocin results in increased expression of and results in increased cleavage of CASP1 protein Streptozocin results in increased expression of CASP1 mRNA; Streptozocin results in increased expression of CASP1 protein [aucubin co-treated with Streptozocin co-treated with Dietary Fats] results in decreased cleavage of CASP1 protein; [Dietary Fats co-treated with Streptozocin] results in increased expression of CASP1 protein; [Streptozocin co-treated with Dextran Sulfate] results in increased cleavage of CASP1 protein; [Streptozocin co-treated with Dietary Fats] results in increased activity of CASP1 protein; GSDMD protein affects the reaction [Streptozocin results in increased cleavage of CASP1 protein]; loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CASP1 protein]; NLRP3 protein promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased activity of CASP1 protein]; Streptozocin results in increased expression of and results in increased cleavage of CASP1 protein |
CTD |
PMID:23647015 PMID:26614261 PMID:27783111 PMID:32202043 PMID:34212273 PMID:34964214 PMID:35961541 PMID:36999408 PMID:37081038 PMID:37473909 More...
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NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290
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G |
Casp12 |
caspase 12 |
increases expression increases cleavage multiple interactions |
EXP ISO |
Streptozocin results in increased expression of CASP12 protein modified form Streptozocin results in increased cleavage of CASP12 protein FGF21 protein affects the reaction [Streptozocin results in increased expression of CASP12 protein modified form]; sulforaphane inhibits the reaction [Streptozocin results in increased cleavage of CASP12 protein] Curcumin inhibits the reaction [Streptozocin results in increased cleavage of CASP12 protein] |
CTD |
PMID:23499715 PMID:24967692 PMID:25541178 |
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NCBI chr 9:5,345,419...5,373,034
Ensembl chr 9:5,345,430...5,373,032
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G |
Casp3 |
caspase 3 |
multiple interactions increases activity decreases cleavage increases cleavage increases expression decreases expression |
ISO EXP |
3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of CASP3 protein; [Rolipram co-treated with Pentoxifylline] inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; [Streptozocin co-treated with Arsenic] results in increased expression of CASP3 mRNA; [Streptozocin co-treated with Cadmium] results in increased expression of CASP3 mRNA; [Streptozocin co-treated with IGF2R protein modified form] results in increased expression of CASP3 protein modified form; [Streptozocin co-treated with Lead co-treated with Manganese co-treated with Cadmium co-treated with Arsenic] results in increased expression of CASP3 mRNA; [Streptozocin co-treated with Lead] results in increased expression of CASP3 mRNA; [Streptozocin co-treated with Manganese] results in increased expression of CASP3 mRNA; Acetylcysteine inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; Anthocyanins inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of CASP3 protein]; Curcumin inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; diallyl trisulfide inhibits the reaction [Streptozocin results in decreased cleavage of CASP3 protein]; Ellagic Acid inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; Ellagic Acid promotes the reaction [sinapinic acid inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]]; ferulic acid analog inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of CASP3 protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; Ibuprofen inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; Ibuprofen inhibits the reaction [Streptozocin results in increased expression of CASP3 mRNA]; Imatinib Mesylate inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; Insulin promotes the reaction [Ozone inhibits the reaction [Streptozocin results in increased expression of CASP3 mRNA]]; Memantine inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; Memantine inhibits the reaction [Streptozocin results in increased expression of CASP3 mRNA]; Metformin inhibits the reaction [Streptozocin results in increased expression of CASP3 mRNA]; morin inhibits the reaction [Streptozocin results in increased expression of CASP3 mRNA]; nifuroxazide inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; nifuroxazide inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Ozone inhibits the reaction [Streptozocin results in increased expression of CASP3 mRNA]; Pentoxifylline inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Phosphocreatine inhibits the reaction [Streptozocin results in decreased expression of CASP3 protein]; Phosphocreatine inhibits the reaction [Streptozocin results in increased expression of CASP3 protein modified form]; Propofol inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Rivastigmine inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; Rolipram inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Rosiglitazone inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; sinapinic acid inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; sinapinic acid promotes the reaction [Ellagic Acid inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]]; Streptozocin results in increased expression of and results in increased cleavage of CASP3 protein; Thioctic Acid inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; Tropisetron inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; Vitamin B 12 inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein] Streptozocin analog results in increased activity of CASP3 protein; Streptozocin results in increased activity of CASP3 protein [Streptozocin co-treated with bisphenol A] results in increased expression of CASP3 mRNA; [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] affects the cleavage of CASP3 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of CASP3 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of CASP3 protein; [Streptozocin co-treated with NQO1 protein mutant form] results in increased expression of CASP3 protein modified form; [Streptozocin co-treated with octylphenol] results in increased expression of CASP3 mRNA; fatostatin promotes the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Metformin inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; montelukast inhibits the reaction [Streptozocin results in increased expression of CASP3 protein modified form]; NTN1 protein inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; phillyrin inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Quercetin inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CASP3 mRNA]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CASP3 protein]; Streptozocin inhibits the reaction [Cisplatin results in increased expression of CASP3 protein]; Streptozocin inhibits the reaction [Ethinyl Estradiol results in decreased expression of CASP3 mRNA]; sulforaphane inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein] Streptozocin results in increased expression of CASP3 mRNA; Streptozocin results in increased expression of CASP3 protein; Streptozocin results in increased expression of CASP3 protein modified form Streptozocin results in increased expression of CASP3 mRNA; Streptozocin results in increased expression of CASP3 protein modified form Streptozocin results in decreased expression of CASP3 mRNA; Streptozocin results in decreased expression of CASP3 protein |
CTD |
PMID:12502508 PMID:15976052 PMID:18721751 PMID:18758938 PMID:19133311 PMID:19682444 PMID:19840221 PMID:19931367 PMID:19951573 PMID:20053369 PMID:20224876 PMID:20424226 PMID:20654064 PMID:21599458 PMID:23267840 PMID:23453443 PMID:23458895 PMID:24333387 PMID:24810525 PMID:24967692 PMID:25541178 PMID:25665769 PMID:26499206 PMID:26614261 PMID:26887929 PMID:27702591 PMID:28856781 PMID:29059224 PMID:29420703 PMID:29606028 PMID:29935216 PMID:30980806 PMID:31029786 PMID:31323227 PMID:32246071 PMID:32710900 PMID:32805344 PMID:33484791 PMID:34455488 PMID:34610774 PMID:34649470 PMID:34661493 PMID:35414346 PMID:36462176 PMID:36504472 PMID:36510688 PMID:37081038 PMID:37352119 PMID:37431890 PMID:38049026 More...
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NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
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G |
Casp4 |
caspase 4, apoptosis-related cysteine peptidase |
increases expression |
EXP |
Streptozocin results in increased expression of CASP4 mRNA |
CTD |
PMID:34212273 |
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NCBI chr 9:5,308,816...5,336,791
Ensembl chr 9:5,308,828...5,336,783
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G |
Casp6 |
caspase 6 |
increases expression |
ISO |
Streptozocin results in increased expression of CASP6 protein |
CTD |
PMID:15976052 |
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NCBI chr 3:129,695,064...129,707,761
Ensembl chr 3:129,695,074...129,707,752
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G |
Casp7 |
caspase 7 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of CASP7 protein [Streptozocin co-treated with Fructose] results in increased expression of CASP7 protein; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of CASP7 protein]; dapagliflozin promotes the reaction [Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of CASP7 protein]]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of CASP7 protein]; Metformin promotes the reaction [dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of CASP7 protein]] |
CTD |
PMID:15976052 PMID:30551545 |
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NCBI chr19:56,382,640...56,430,780
Ensembl chr19:56,385,561...56,430,776
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G |
Casp8 |
caspase 8 |
multiple interactions increases expression increases cleavage increases activity |
ISO |
Anthocyanins inhibits the reaction [Streptozocin results in increased expression of CASP8 protein]; Curcumin inhibits the reaction [Streptozocin results in increased cleavage of CASP8 protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of CASP8 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of CASP8 mRNA]; nifuroxazide inhibits the reaction [Streptozocin results in increased activity of CASP8 protein] Streptozocin results in increased expression of CASP8 mRNA; Streptozocin results in increased expression of CASP8 protein |
CTD |
PMID:23267840 PMID:25541178 PMID:28856781 PMID:29606028 |
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NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662
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G |
Casp9 |
caspase 9 |
multiple interactions increases expression increases activity decreases expression |
ISO EXP |
[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of CASP9 protein; Anthocyanins inhibits the reaction [Streptozocin results in increased expression of CASP9 protein]; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of CASP9 protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of CASP9 protein]; IGF2R protein modified form inhibits the reaction [Streptozocin results in increased expression of CASP9 protein]; Insulin promotes the reaction [Ozone inhibits the reaction [Streptozocin results in increased expression of CASP9 mRNA]]; nifuroxazide inhibits the reaction [Streptozocin results in increased activity of CASP9 protein]; Ozone inhibits the reaction [Streptozocin results in increased expression of CASP9 mRNA]; Phosphocreatine inhibits the reaction [Streptozocin results in decreased expression of CASP9 protein]; Streptozocin results in increased expression of and results in increased cleavage of CASP9 protein; Thioctic Acid inhibits the reaction [Streptozocin results in increased expression of CASP9 protein] Streptozocin results in increased expression of CASP9 mRNA; Streptozocin results in increased expression of CASP9 protein [Streptozocin co-treated with Dietary Fats] results in increased expression of CASP9 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of CASP9 protein; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CASP9 mRNA]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CASP9 protein] |
CTD |
PMID:15976052 PMID:19951573 PMID:22940631 PMID:26614261 PMID:28856781 PMID:29606028 PMID:34455488 PMID:34610774 PMID:36462176 PMID:36510688 More...
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NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
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G |
Cat |
catalase |
increases expression multiple interactions decreases response to substance increases phosphorylation decreases expression increases activity decreases activity |
EXP ISO |
Streptozocin results in increased expression of CAT mRNA Streptozocin results in increased expression of CAT protein CAT protein promotes the reaction [SOD2 protein results in decreased susceptibility to Streptozocin]; SOD2 protein promotes the reaction [CAT protein results in decreased susceptibility to Streptozocin] Streptozocin results in increased phosphorylation of CAT protein Streptozocin results in decreased expression of CAT; Streptozocin results in decreased expression of CAT mRNA 2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; [Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein; [Dietary Fats co-treated with Streptozocin] results in decreased expression of CAT mRNA; [Streptozocin co-treated with Dextran Sulfate] results in decreased expression of CAT protein; [Streptozocin co-treated with Dietary Fats] results in decreased activity of CAT protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein; [Streptozocin co-treated with INS1 protein co-treated with Glutathione] affects the expression of CAT mRNA; [Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein; Acrylamide promotes the reaction [Streptozocin results in decreased activity of CAT protein]; Alendronate inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein]; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein]; Donepezil inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; pterostilbene inhibits the reaction [Streptozocin results in decreased expression of CAT]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; rhodioloside inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of CAT mRNA]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of CAT protein] Streptozocin results in decreased expression of CAT mRNA; Streptozocin results in decreased expression of CAT protein 1,3-dimethoxy-5-methyl-2-(3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl)benzene inhibits the reaction [4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in increased expression of CAT protein]]; 2-hydroxy-4-methoxy benzoic acid inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; 4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in increased expression of CAT protein]; 4-methyl-2-((2-methylbenzyl) amino)-1,3-thiazole-5-carboxylic acid inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; 5,3'-dihydroxy-3,6,7,4',5'-pentamethoxyflavone inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; [Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein; [Dietary Fats co-treated with Streptozocin] results in decreased expression of CAT protein; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein; [Fructose co-treated with Streptozocin] results in decreased activity of CAT protein; [Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein]; [Niacinamide co-treated with Streptozocin] results in decreased activity of CAT protein; [Phytic Acid co-treated with Inositol] inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; [pimagedine co-treated with Fatty Acids, Omega-3] inhibits the reaction [Streptozocin results in increased activity of CAT protein]; [Propolis co-treated with Chlorpyrifos co-treated with Streptozocin] results in increased activity of CAT protein; [Propolis co-treated with Streptozocin] results in increased activity of CAT protein; [Quercetin co-treated with coenzyme Q10] inhibits the reaction [Streptozocin results in increased activity of CAT protein]; [Quercetin co-treated with Streptozocin] results in increased activity of CAT protein; [Rosiglitazone co-treated with Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein; [Streptozocin co-treated with bisphenol A] results in decreased expression of CAT protein; [Streptozocin co-treated with Chlorpyrifos] results in increased activity of CAT protein; [Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the activity of CAT protein; [Streptozocin co-treated with Dietary Fats] results in decreased activity of CAT protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein; [Streptozocin co-treated with Isoproterenol] affects the activity of CAT protein; [Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of CAT protein; [Zinc co-treated with Selenium] inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; [Zinc Sulfate results in increased abundance of Zinc] inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; allyl methyl sulfide inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; alpha-Tocopherol inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; arjunolic acid inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; asiatic acid inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Berberine affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the activity of CAT protein]; Bezafibrate inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein]; caryophyllene inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; CAT protein inhibits the reaction [Streptozocin results in increased expression of GNA11 protein]; CAT protein inhibits the reaction [Streptozocin results in increased expression of GNAQ protein]; CAT protein inhibits the reaction [Streptozocin results in increased expression of PLCB1 protein]; CAT protein inhibits the reaction [Streptozocin results in increased expression of PLCB2 protein]; Chlorpyrifos promotes the reaction [Streptozocin results in increased activity of CAT protein]; Chromium inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; chromium tripicolinate inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; corilagin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; coumarin inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in decreased activity of CAT protein]; crocin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; dapagliflozin inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; Diltiazem inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Dimethyl Fumarate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein]; Diosmin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of CAT mRNA]; Ellagic Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein]; eupafolin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of CAT protein]; fenugreek seed meal inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Ficusin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased activity of CAT protein]; Gallic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased activity of CAT protein]; Gallic Acid inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; geraniol inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Gliclazide inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in decreased activity of CAT protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; Gliclazide inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein]; Glyburide inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; hesperetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein]; Imatinib Mesylate inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Imipramine inhibits the reaction [Streptozocin results in increased activity of CAT protein]; INS1 protein inhibits the reaction [Streptozocin results in increased activity of CAT protein]; isoquercitrin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Losartan inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; mangiferin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Melatonin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Metformin inhibits the reaction [[Fructose co-treated with Streptozocin] results in decreased activity of CAT protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein]; Metformin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Metformin inhibits the reaction [Streptozocin results in decreased expression of CAT mRNA]; morin analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased activity of CAT protein]; morin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; myrsinoic acid B inhibits the reaction [Streptozocin results in increased activity of CAT protein]; myrtenol inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; naringenin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; nerolidol inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein]; notoginsenoside R1 inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; palbinone inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; pinitol inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Pioglitazone inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased activity of CAT protein]; Pioglitazone inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; Pioglitazone inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; piperlongumine inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; Plant Extracts inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein]; Propolis inhibits the reaction [[Streptozocin co-treated with Chlorpyrifos] results in increased activity of CAT protein]; Propolis inhibits the reaction [Streptozocin results in increased activity of CAT protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of CAT protein]; Quercetin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Quercetin inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; Quercetin inhibits the reaction [Streptozocin results in increased activity of CAT protein]; Resveratrol inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in decreased activity of CAT protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of and results in decreased activity of CAT protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of CAT mRNA]; Resveratrol promotes the reaction [Streptozocin results in decreased expression of CAT mRNA]; rhapontin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Rosiglitazone affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the activity of CAT protein]; S-allylcysteine inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; Saponins inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; sodium arsenate promotes the reaction [Streptozocin results in decreased activity of CAT protein]; Sodium Selenite inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Streptozocin inhibits the reaction [Lipopolysaccharides results in increased expression of CAT protein]; Streptozocin inhibits the reaction [Streptozocin results in increased expression of CAT protein]; Streptozocin promotes the reaction [Chlorpyrifos results in increased activity of CAT protein]; Streptozocin results in decreased expression of and results in decreased activity of CAT protein; Streptozocin results in increased expression of and results in increased activity of CAT protein; Thioctic Acid inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; thymoquinone inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; Tocotrienols inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; U 78517F inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; vanillin inhibits the reaction [[Fructose co-treated with Streptozocin] results in decreased activity of CAT protein]; Zinc Compounds inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased activity of CAT protein]; Zinc inhibits the reaction [Streptozocin results in decreased activity of CAT protein] |
CTD |
PMID:9522273 PMID:11424224 PMID:12123627 PMID:12242689 PMID:15298345 PMID:15821039 PMID:15855331 PMID:15957552 PMID:16177186 PMID:16581090 PMID:16780994 PMID:17042909 PMID:17145126 PMID:18779489 PMID:19133311 PMID:19464315 PMID:19682444 PMID:19840221 PMID:19931367 PMID:20053369 PMID:20307516 PMID:20643114 PMID:20691780 PMID:20828602 PMID:20951120 PMID:21382363 PMID:21439372 PMID:21457706 PMID:21630391 PMID:22056647 PMID:22476978 PMID:22733486 PMID:23122718 PMID:23677724 PMID:23716880 PMID:24740756 PMID:24752916 PMID:24760747 PMID:24854284 PMID:24877639 PMID:24954035 PMID:24967692 PMID:25057273 PMID:25362599 PMID:25503068 PMID:25617480 PMID:25986969 PMID:26286521 PMID:26286522 PMID:26341651 PMID:26499206 PMID:26690102 PMID:26700463 PMID:26748309 PMID:27350165 PMID:28178614 PMID:28757134 PMID:29223569 PMID:29233026 PMID:29247773 PMID:29274332 PMID:29331653 PMID:29409856 PMID:29441829 PMID:29988851 PMID:30144451 PMID:30318971 PMID:30481507 PMID:30582900 PMID:30817903 PMID:30847815 PMID:30958922 PMID:31009641 PMID:31100278 PMID:31400774 PMID:31682803 PMID:32202043 PMID:32233808 PMID:32662907 PMID:32710900 PMID:32812462 PMID:32864810 PMID:33359794 PMID:33639173 PMID:33724628 PMID:33823243 PMID:34039237 PMID:34352274 PMID:34477272 PMID:34610774 PMID:34896238 PMID:34922902 PMID:34964214 PMID:35187753 PMID:35414346 PMID:35961541 PMID:36169646 PMID:36510688 PMID:36999408 PMID:37120126 PMID:37352119 PMID:37354076 PMID:37482253 PMID:37566541 PMID:38602238 PMID:39299373 More...
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NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
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G |
Cav1 |
caveolin 1, caveolae protein |
multiple interactions increases expression |
ISO |
resveratrol inhibits the reaction [Streptozocin promotes the reaction [CAV1 protein binds to NOS3 protein]]; resveratrol inhibits the reaction [Streptozocin results in increased expression of CAV1 protein]; Streptozocin promotes the reaction [CAV1 protein binds to NOS3 protein] |
CTD |
PMID:18266981 |
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NCBI chr 6:17,306,387...17,341,323
Ensembl chr 6:17,306,334...17,341,451
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G |
Cav3 |
caveolin 3 |
multiple interactions decreases expression |
ISO |
resveratrol inhibits the reaction [Streptozocin inhibits the reaction [CAV3 protein binds to SLC2A4 protein]]; resveratrol inhibits the reaction [Streptozocin results in decreased expression of CAV3 protein]; Streptozocin inhibits the reaction [CAV3 protein binds to SLC2A4 protein] |
CTD |
PMID:18266981 |
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NCBI chr 6:112,436,466...112,449,833
Ensembl chr 6:112,436,466...112,449,833
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G |
Cbr1 |
carbonyl reductase 1 |
decreases activity |
ISO |
Streptozocin results in decreased activity of CBR1 protein |
CTD |
PMID:11057757 |
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NCBI chr16:93,404,752...93,407,226
Ensembl chr16:93,402,741...93,407,393
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G |
Cbs |
cystathionine beta-synthase |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of CBS mRNA |
CTD |
PMID:29127188 |
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NCBI chr17:31,831,602...31,856,170
Ensembl chr17:31,827,868...31,856,212
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
increases expression affects response to substance multiple interactions increases secretion |
EXP ISO |
Streptozocin results in increased expression of CCL2; Streptozocin results in increased expression of CCL2 mRNA; Streptozocin results in increased expression of CCL2 protein CCL2 affects the susceptibility to Streptozocin [Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of CCL2 protein; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of CCL2 protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; Flavonoids inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of CCL2 protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; moutan cortex inhibits the reaction [Streptozocin results in increased expression of and results in increased secretion of CCL2 protein]; Mycophenolic Acid inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; Mycophenolic Acid inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]; PD 123319 inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; Pentoxifylline inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]; procyanidin B2 inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; prolinedithiocarbamate inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]; Rosiglitazone inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; Streptozocin results in increased expression of and results in increased secretion of CCL2 protein; Valsartan inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]; vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA] 4-(4-(3-adamantan-1-ylureido)cyclohexyloxy)benzoic acid inhibits the reaction [Streptozocin results in increased secretion of CCL2 protein]; [AM6545 co-treated with Perindopril] inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; [AM6545 co-treated with Perindopril] inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of CCL2 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of CCL2 protein; [fatostatin co-treated with Streptozocin] results in increased expression of CCL2 protein; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of CCL2 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased secretion of CCL2 protein; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased secretion of CCL2 protein]; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]; EPHX2 gene mutant form inhibits the reaction [Streptozocin results in increased secretion of CCL2 protein]; esculetin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CCL2 protein]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CCL2 mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of CCL2 mRNA]; stannous mesoporphyrin inhibits the reaction [4-(4-(3-adamantan-1-ylureido)cyclohexyloxy)benzoic acid inhibits the reaction [Streptozocin results in increased secretion of CCL2 protein]]; Valsartan inhibits the reaction [Streptozocin results in increased expression of CCL2 protein] |
CTD |
PMID:15284299 PMID:16374426 PMID:16684804 PMID:17624267 PMID:18413206 PMID:18999900 PMID:19921414 PMID:21832210 PMID:23611540 PMID:24513509 PMID:25199697 PMID:27664441 PMID:27769711 PMID:29266779 PMID:29420703 PMID:29988851 PMID:30184259 PMID:30551545 PMID:31696645 PMID:33639173 PMID:37482253 PMID:39047806 More...
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NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
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G |
Ccl3 |
C-C motif chemokine ligand 3 |
multiple interactions increases expression |
EXP |
AM6545 inhibits the reaction [Streptozocin results in increased expression of CCL3 mRNA]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in increased expression of CCL3 mRNA]]; Perindopril inhibits the reaction [Streptozocin results in increased expression of CCL3 mRNA]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in increased expression of CCL3 mRNA]] |
CTD |
PMID:30184259 |
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NCBI chr11:83,538,669...83,540,204
Ensembl chr11:83,538,670...83,540,181
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G |
Ccl5 |
C-C motif chemokine ligand 5 |
increases expression |
EXP |
Streptozocin results in increased expression of CCL5 mRNA |
CTD |
PMID:29420703 |
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NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344
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G |
Ccl6 |
C-C motif chemokine ligand 6 |
multiple interactions |
ISO |
[Resveratrol co-treated with Streptozocin] results in increased expression of CCL6 mRNA |
CTD |
PMID:25905778 |
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NCBI chr11:83,478,712...83,483,913
Ensembl chr11:83,478,708...83,483,913
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G |
Ccn2 |
cellular communication network factor 2 |
increases expression multiple interactions |
EXP ISO |
Streptozocin results in increased expression of CCN2; Streptozocin results in increased expression of CCN2 protein [Streptozocin co-treated with Resveratrol co-treated with Ramipril] results in decreased expression of CCN2 protein; Acetylcysteine inhibits the reaction [Streptozocin results in increased expression of CCN2 protein]; Aspirin inhibits the reaction [Streptozocin results in increased expression of CCN2 mRNA]; Enalapril inhibits the reaction [Streptozocin results in increased expression of CCN2 protein]; fenugreek seed meal inhibits the reaction [Streptozocin results in increased expression of CCN2 mRNA]; fenugreek seed meal inhibits the reaction [Streptozocin results in increased expression of CCN2 protein]; idebenone inhibits the reaction [Streptozocin results in increased expression of CCN2 protein]; XLF-III-43 inhibits the reaction [Streptozocin results in increased expression of CCN2 protein]; Zinc inhibits the reaction [Streptozocin results in increased expression of CCN2 protein] [Dietary Fats co-treated with Streptozocin] promotes the reaction [KLF15 gene mutant form results in increased expression of CCN2 protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of CCN2 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of CCN2 protein; CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CCN2 protein]; KLF15 gene mutant form inhibits the reaction [CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CCN2 protein]]; KLF15 gene mutant form promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CCN2 protein]; sulforaphane inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CCN2 protein]; sulforaphane inhibits the reaction [Streptozocin results in increased expression of CCN2 protein] Streptozocin results in increased expression of CCN2 mRNA; Streptozocin results in increased expression of CCN2 protein |
CTD |
PMID:10026205 PMID:14586741 PMID:17270171 PMID:19369054 PMID:19657322 PMID:19895808 PMID:21416479 PMID:24707343 PMID:24967692 PMID:25057273 PMID:28648635 PMID:31062909 PMID:34175429 PMID:34310909 More...
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NCBI chr10:24,471,340...24,474,581
Ensembl chr10:24,471,340...24,474,581
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G |
Ccnd1 |
cyclin D1 |
decreases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of CCND1 mRNA 5-Methoxypsoralen inhibits the reaction [Streptozocin results in decreased expression of CCND1 mRNA]; Tadalafil inhibits the reaction [Streptozocin results in decreased expression of CCND1 mRNA] |
CTD |
PMID:34428446 |
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NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662
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G |
Ccnd2 |
cyclin D2 |
decreases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of CCND2 protein AM 251 inhibits the reaction [Streptozocin results in decreased expression of CCND2 protein]; CNR1 protein promotes the reaction [Streptozocin results in decreased expression of CCND2 protein] |
CTD |
PMID:26967640 |
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NCBI chr 6:127,102,125...127,131,913
Ensembl chr 6:127,102,125...127,129,156
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G |
Ccnt1 |
cyclin T1 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 mRNA; [Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 protein; Berberine affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 mRNA]; Berberine affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 protein]; Fenofibrate affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 mRNA]; Fenofibrate affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 protein]; rosiglitazone affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 mRNA]; rosiglitazone affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 protein] |
CTD |
PMID:20828602 |
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NCBI chr15:98,436,570...98,468,340
Ensembl chr15:98,436,570...98,468,804
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G |
Ccr2 |
C-C motif chemokine receptor 2 |
multiple interactions increases expression |
EXP |
[AM6545 co-treated with Perindopril] inhibits the reaction [Streptozocin results in increased expression of CCR2 mRNA]; AM6545 inhibits the reaction [Streptozocin results in increased expression of CCR2 mRNA]; Perindopril inhibits the reaction [Streptozocin results in increased expression of CCR2 mRNA] |
CTD |
PMID:30184259 |
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NCBI chr 9:123,901,954...123,913,594
Ensembl chr 9:123,901,987...123,913,594
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G |
Ccs |
copper chaperone for superoxide dismutase |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of CCS mRNA; Streptozocin results in decreased expression of CCS protein Trientine inhibits the reaction [Streptozocin results in decreased expression of CCS mRNA]; Trientine inhibits the reaction [Streptozocin results in decreased expression of CCS protein] |
CTD |
PMID:24927960 |
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NCBI chr19:4,875,394...4,889,326
Ensembl chr19:4,875,394...4,889,360
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G |
Cd14 |
CD14 antigen |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of CD14 mRNA |
CTD |
PMID:29127188 |
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NCBI chr18:36,858,117...36,859,868
Ensembl chr18:36,858,120...36,859,851
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G |
Cd163 |
CD163 antigen |
multiple interactions decreases expression |
ISO EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of CD163 mRNA Streptozocin results in decreased expression of CD163 mRNA AM6545 inhibits the reaction [Streptozocin results in decreased expression of CD163 mRNA]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in decreased expression of CD163 mRNA]]; Perindopril inhibits the reaction [Streptozocin results in decreased expression of CD163 mRNA]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in decreased expression of CD163 mRNA]] |
CTD |
PMID:25905778 PMID:30184259 |
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NCBI chr 6:124,281,596...124,307,488
Ensembl chr 6:124,281,615...124,307,486
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G |
Cd200r4 |
CD200 receptor 4 |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of CD200R1L mRNA |
CTD |
PMID:25905778 |
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NCBI chr16:44,632,036...44,659,497
Ensembl chr16:44,632,096...44,659,513
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G |
Cd24a |
CD24a antigen |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of CD24A mRNA |
CTD |
PMID:29127188 |
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NCBI chr10:43,454,433...43,460,261
Ensembl chr10:43,454,280...43,460,261
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G |
Cd36 |
CD36 molecule |
multiple interactions increases expression |
EXP |
[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of CD36 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of CD36 mRNA; Acrylamide inhibits the reaction [Streptozocin results in increased expression of CD36 mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of CD36 mRNA] |
CTD |
PMID:29127188 PMID:34896238 PMID:39047806 |
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NCBI chr 5:17,986,680...18,093,828
Ensembl chr 5:17,986,688...18,093,799
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G |
Cd53 |
CD53 antigen |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of CD53 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 3:106,666,177...106,697,465
Ensembl chr 3:106,667,237...106,697,465
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G |
Cd5l |
CD5 antigen-like |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of CD5L mRNA |
CTD |
PMID:25905778 |
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NCBI chr 3:87,265,188...87,278,381
Ensembl chr 3:87,265,188...87,278,380
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G |
Cd68 |
CD68 antigen |
multiple interactions increases expression |
ISO EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of CD68 mRNA; nifuroxazide inhibits the reaction [Streptozocin results in increased expression of CD68 protein] [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of CD68 mRNA; AM6545 inhibits the reaction [Streptozocin results in increased expression of CD68 mRNA]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in increased expression of CD68 mRNA]]; Perindopril inhibits the reaction [Streptozocin results in increased expression of CD68 mRNA]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in increased expression of CD68 mRNA]]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of CD68 mRNA] |
CTD |
PMID:25905778 PMID:29291386 PMID:30184259 PMID:39047806 |
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NCBI chr11:69,555,039...69,556,996
Ensembl chr11:69,555,039...69,556,979
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G |
Cd80 |
CD80 antigen |
multiple interactions increases expression |
EXP |
Clodronic Acid inhibits the reaction [Streptozocin results in increased expression of CD80 protein] |
CTD |
PMID:15892581 |
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NCBI chr16:38,277,793...38,316,682
Ensembl chr16:38,275,923...38,316,697
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G |
Cd86 |
CD86 antigen |
multiple interactions increases expression |
EXP ISO |
Clodronic Acid inhibits the reaction [Streptozocin results in increased expression of CD86 protein] [resveratrol co-treated with Streptozocin] results in increased expression of CD86 mRNA |
CTD |
PMID:15892581 PMID:25905778 |
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NCBI chr16:36,389,318...36,486,439
Ensembl chr16:36,424,231...36,486,443
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G |
Cdca2 |
cell division cycle associated 2 |
multiple interactions |
EXP |
[Diethylhexyl Phthalate co-treated with Streptozocin co-treated with Dietary Fats] results in increased expression of CDCA2 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of CDCA2 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CDCA2 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr14:67,910,629...67,953,290
Ensembl chr14:67,913,780...67,953,290
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G |
Cdcp3 |
CUB domain containing protein 3 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of CDCP3 mRNA |
CTD |
PMID:33484791 |
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NCBI chr 7:130,776,131...130,908,181
Ensembl chr 7:130,776,131...130,908,180
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G |
Cdh1 |
cadherin 1 |
decreases expression |
ISO |
Streptozocin results in decreased expression of CDH1 |
CTD |
PMID:32469605 |
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NCBI chr 8:107,329,982...107,396,879
Ensembl chr 8:107,329,983...107,396,878
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G |
Cdh2 |
cadherin 2 |
multiple interactions decreases expression |
EXP |
rhodioloside inhibits the reaction [Streptozocin results in decreased expression of CDH2 protein] |
CTD |
PMID:31682803 |
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NCBI chr18:16,721,934...16,942,303
Ensembl chr18:16,721,934...16,942,303
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G |
Cdk15 |
cyclin dependent kinase 15 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of CDK15 mRNA |
CTD |
PMID:33484791 |
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NCBI chr 1:59,296,029...59,391,656
Ensembl chr 1:59,296,065...59,392,152
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G |
Cdk9 |
cyclin dependent kinase 9 |
multiple interactions increases phosphorylation |
ISO EXP |
[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 mRNA; [Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 protein; Berberine affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 mRNA]; Berberine affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 protein]; Fenofibrate affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 mRNA]; Fenofibrate affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 protein]; rosiglitazone affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 mRNA]; rosiglitazone affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 protein] Streptozocin results in increased phosphorylation of CDK9 protein |
CTD |
PMID:20828602 PMID:33631230 |
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NCBI chr 2:32,595,794...32,608,098
Ensembl chr 2:32,595,796...32,603,088
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G |
Cdkn1a |
cyclin dependent kinase inhibitor 1A |
multiple interactions increases expression |
EXP ISO |
2-amino-6-boronohexanoic acid inhibits the reaction [Streptozocin results in increased expression of CDKN1A mRNA]; [Dietary Fats co-treated with Streptozocin] results in increased expression of CDKN1A protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of CDKN1A mRNA; Quercetin inhibits the reaction [Streptozocin results in increased expression of CDKN1A mRNA]; SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of CDKN1A] Streptozocin results in increased expression of CDKN1A; Streptozocin results in increased expression of CDKN1A mRNA Streptozocin results in increased expression of CDKN1A mRNA; Streptozocin results in increased expression of CDKN1A protein Organoselenium Compounds inhibits the reaction [Streptozocin results in increased expression of CDKN1A protein]; Streptozocin promotes the reaction [SETD7 protein binds to CDKN1A promoter] |
CTD |
PMID:19496084 PMID:22744176 PMID:25301743 PMID:27652271 PMID:29127188 PMID:29673160 PMID:38483099 More...
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NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701
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G |
Cdkn2a |
cyclin dependent kinase inhibitor 2A |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of CDKN2A mRNA; Streptozocin results in increased expression of CDKN2A protein 2-amino-6-boronohexanoic acid inhibits the reaction [Streptozocin results in increased expression of CDKN2A mRNA]; 2-amino-6-boronohexanoic acid inhibits the reaction [Streptozocin results in increased expression of CDKN2A protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of CDKN2A protein; NTN1 protein inhibits the reaction [Streptozocin results in increased expression of CDKN2A mRNA]; NTN1 protein inhibits the reaction [Streptozocin results in increased expression of CDKN2A protein] |
CTD |
PMID:29059224 PMID:29673160 PMID:38483099 |
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NCBI chr 4:89,192,710...89,212,856
Ensembl chr 4:89,192,708...89,212,890
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G |
Cebpb |
CCAAT/enhancer binding protein beta |
multiple interactions decreases expression |
EXP |
CEBPB protein affects the reaction [Streptozocin results in increased expression of AGT protein]; CEBPB protein affects the reaction [Streptozocin results in increased expression of TGFB1 protein]; CEBPB protein inhibits the reaction [Streptozocin results in decreased abundance of AGT protein modified form]; CEBPB protein inhibits the reaction [Streptozocin results in decreased abundance of angiotensin I (1-7)]; CEBPB protein inhibits the reaction [Streptozocin results in decreased expression of ACE2 protein]; CEBPB protein inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; CEBPB protein inhibits the reaction [Streptozocin results in decreased expression of MAS1 protein]; CEBPB protein inhibits the reaction [Streptozocin results in decreased expression of MMP2 protein]; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of ACE protein]; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of AGTR1 protein]; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of AGTR2 protein]; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of BAX protein]; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of IL6 protein] Streptozocin results in decreased expression of CEBPB protein |
CTD |
PMID:29266779 |
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NCBI chr 2:167,530,835...167,532,352
Ensembl chr 2:167,530,835...167,532,338
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G |
Cebpd |
CCAAT/enhancer binding protein delta |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of CEBPD mRNA |
CTD |
PMID:25905778 |
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NCBI chr16:15,705,150...15,707,409
Ensembl chr16:15,705,150...15,708,895
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G |
Celf2 |
CUGBP, Elav-like family member 2 |
multiple interactions |
EXP |
[Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of CELF2 mRNA]; [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of CELF2 protein]; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of CELF2 mRNA; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of CELF2 protein |
CTD |
PMID:38282657 |
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NCBI chr 2:6,544,505...7,401,345
Ensembl chr 2:6,544,505...7,514,374
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G |
Celf4 |
CUGBP, Elav-like family member 4 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of CELF4 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CELF4 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr18:25,610,677...25,887,577
Ensembl chr18:25,610,689...25,887,214
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G |
Ces2c |
carboxylesterase 2C |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of CES2C mRNA |
CTD |
PMID:25905778 |
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NCBI chr 8:105,573,700...105,581,115
Ensembl chr 8:105,573,700...105,581,115
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G |
Ces2d-ps |
carboxylesterase 2D, pseudogene |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of CES2D-PS mRNA |
CTD |
PMID:33484791 |
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NCBI chr 8:105,594,056...105,600,715
Ensembl chr 8:105,594,120...105,600,493
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G |
Ces4a |
carboxylesterase 4A |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of CES4A mRNA |
CTD |
PMID:33484791 |
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NCBI chr 8:105,858,432...105,876,741
Ensembl chr 8:105,858,432...105,876,741
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G |
Cfap45 |
cilia and flagella associated protein 45 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of CFAP45 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CFAP45 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 1:172,348,697...172,373,437
Ensembl chr 1:172,348,368...172,373,437
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G |
Cfap69 |
cilia and flagella associated protein 69 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of CFAP69 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CFAP69 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 5:5,629,284...5,714,232
Ensembl chr 5:5,629,278...5,714,239
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G |
Cfd |
complement factor D |
increases expression |
ISO |
Streptozocin results in increased expression of CFD mRNA |
CTD |
PMID:3299706 |
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NCBI chr10:79,726,687...79,728,489
Ensembl chr10:79,726,687...79,728,489
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G |
Cfl1 |
cofilin 1, non-muscle |
multiple interactions increases phosphorylation |
ISO |
fasudil inhibits the reaction [Streptozocin results in increased phosphorylation of CFL1 protein] |
CTD |
PMID:22062134 |
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NCBI chr19:5,540,483...5,544,059
Ensembl chr19:5,540,483...5,545,229
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G |
Cfp |
complement factor properdin |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of CFP mRNA |
CTD |
PMID:25905778 |
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NCBI chr X:20,791,693...20,797,794
Ensembl chr X:20,791,693...20,797,794
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G |
Chat |
choline O-acetyltransferase |
multiple interactions affects localization decreases expression |
ISO |
Inositol inhibits the reaction [Streptozocin affects the localization of CHAT protein]; Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of CHAT protein]; Rivastigmine inhibits the reaction [Streptozocin results in decreased expression of CHAT protein] |
CTD |
PMID:2431858 PMID:32805344 |
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NCBI chr14:32,130,160...32,187,866
Ensembl chr14:32,130,160...32,187,946
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G |
Chga |
chromogranin A |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of CHGA mRNA |
CTD |
PMID:33484791 |
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NCBI chr12:102,521,200...102,531,286
Ensembl chr12:102,521,228...102,531,287
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G |
Chil3 |
chitinase-like 3 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of CHIL3 mRNA |
CTD |
PMID:33484791 |
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NCBI chr 3:106,054,870...106,074,852
Ensembl chr 3:106,054,870...106,074,880
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G |
Chka |
choline kinase alpha |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of CHKA mRNA |
CTD |
PMID:29127188 |
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NCBI chr19:3,901,585...3,944,368
Ensembl chr19:3,901,773...3,944,369
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G |
Chrm2 |
cholinergic receptor, muscarinic 2, cardiac |
multiple interactions affects expression increases expression |
ISO |
1-hexacosanol inhibits the reaction [Streptozocin affects the expression of CHRM2 mRNA]; Phlorhizin inhibits the reaction [Streptozocin results in increased expression of CHRM2 mRNA]; Phlorhizin inhibits the reaction [Streptozocin results in increased expression of CHRM2 protein] Streptozocin results in increased expression of CHRM2 mRNA; Streptozocin results in increased expression of CHRM2 protein |
CTD |
PMID:17989502 PMID:18715473 |
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NCBI chr 6:36,364,928...36,505,573
Ensembl chr 6:36,365,019...36,505,349
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G |
Chrm3 |
cholinergic receptor, muscarinic 3, cardiac |
multiple interactions affects expression |
ISO |
1-hexacosanol inhibits the reaction [Streptozocin affects the expression of CHRM3 mRNA] |
CTD |
PMID:17989502 |
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NCBI chr13:9,925,522...10,411,131
Ensembl chr13:9,925,522...10,410,883
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G |
Chrna4 |
cholinergic receptor, nicotinic, alpha polypeptide 4 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of CHRNA4 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CHRNA4 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 2:180,664,104...180,685,339
Ensembl chr 2:180,660,173...180,685,339
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G |
Chst8 |
carbohydrate sulfotransferase 8 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of CHST8 mRNA |
CTD |
PMID:33484791 |
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NCBI chr 7:34,373,893...34,512,136
Ensembl chr 7:34,373,893...34,512,136
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G |
Chuk |
conserved helix-loop-helix ubiquitous kinase |
multiple interactions increases expression |
ISO |
Quercetin inhibits the reaction [Streptozocin results in increased expression of CHUK protein] |
CTD |
PMID:16177186 |
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NCBI chr19:44,061,773...44,095,940
Ensembl chr19:44,061,774...44,095,919
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G |
Cidea |
cell death-inducing DNA fragmentation factor, alpha subunit-like effector A |
multiple interactions |
ISO EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of CIDEA mRNA [Streptozocin co-treated with Dietary Fats] results in increased expression of CIDEA mRNA |
CTD |
PMID:25905778 PMID:29127188 |
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NCBI chr18:67,476,634...67,500,864
Ensembl chr18:67,476,674...67,500,855
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G |
Cisd1 |
CDGSH iron sulfur domain 1 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of CISD1 protein Trientine inhibits the reaction [Streptozocin results in increased expression of CISD1 protein] |
CTD |
PMID:19634143 |
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NCBI chr10:71,166,324...71,180,679
Ensembl chr10:71,166,310...71,180,784
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G |
Cited2 |
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
increases expression multiple interactions decreases expression |
ISO EXP |
Streptozocin results in increased expression of CITED2 mRNA vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of CITED2 mRNA] SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of CITED2 mRNA] |
CTD |
PMID:16684804 PMID:27629361 |
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NCBI chr10:17,598,452...17,601,422
Ensembl chr10:17,598,966...17,601,422
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G |
Ckmt2 |
creatine kinase, mitochondrial 2 |
multiple interactions decreases expression |
ISO |
vanadyl sulfate inhibits the reaction [Streptozocin results in decreased expression of CKMT2 mRNA] |
CTD |
PMID:16684804 |
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NCBI chr13:92,001,510...92,025,001
Ensembl chr13:92,001,506...92,025,004
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G |
Cldn1 |
claudin 1 |
decreases expression |
ISO |
Streptozocin results in decreased expression of CLDN1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr16:26,175,395...26,190,589
Ensembl chr16:26,175,392...26,190,591
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G |
Cldn11 |
claudin 11 |
multiple interactions decreases expression |
EXP |
rhodioloside inhibits the reaction [Streptozocin results in decreased expression of CLDN11 protein] |
CTD |
PMID:31682803 |
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NCBI chr 3:31,204,069...31,218,475
Ensembl chr 3:31,204,069...31,218,473
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G |
Cldn2 |
claudin 2 |
decreases expression |
ISO |
Streptozocin results in decreased expression of CLDN2 mRNA |
CTD |
PMID:25905778 |
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NCBI chr X:138,701,552...138,712,135
Ensembl chr X:138,701,577...138,712,135
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G |
Clec4d |
C-type lectin domain family 4, member d |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of CLEC4D mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CLEC4D mRNA] |
CTD |
PMID:33484791 |
|
NCBI chr 6:123,239,066...123,252,227
Ensembl chr 6:123,239,070...123,252,224
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G |
Clec4f |
C-type lectin domain family 4, member f |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of CLEC4F mRNA |
CTD |
PMID:25905778 |
|
NCBI chr 6:83,621,524...83,633,098
Ensembl chr 6:83,621,524...83,633,169
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G |
Clic4 |
chloride intracellular channel 4 |
affects expression |
EXP |
Streptozocin affects the expression of CLIC4 mRNA |
CTD |
PMID:18583417 |
|
NCBI chr 4:134,941,280...135,000,071
Ensembl chr 4:134,941,280...135,000,125
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G |
Clpp |
caseinolytic mitochondrial matrix peptidase proteolytic subunit |
affects expression |
EXP |
Streptozocin affects the expression of CLPP mRNA |
CTD |
PMID:18583417 |
|
NCBI chr17:57,297,264...57,303,371
Ensembl chr17:57,297,305...57,303,188
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G |
Clu |
clusterin |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of CLU protein Trientine inhibits the reaction [Streptozocin results in increased expression of CLU protein] |
CTD |
PMID:19634143 |
|
NCBI chr14:66,206,093...66,218,992
Ensembl chr14:66,205,932...66,218,996
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G |
Cnpy1 |
canopy FGF signaling regulator 1 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of CNPY1 mRNA |
CTD |
PMID:33484791 |
|
NCBI chr 5:28,405,817...28,450,786
Ensembl chr 5:28,405,817...28,450,804
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G |
Cnr1 |
cannabinoid receptor 1 |
multiple interactions decreases expression increases expression |
ISO EXP |
[Fructose co-treated with Streptozocin] results in decreased expression of CNR1 mRNA; Ghrelin inhibits the reaction [[Fructose co-treated with Streptozocin] results in decreased expression of CNR1 mRNA] Streptozocin results in decreased expression of CNR1 protein Streptozocin results in increased expression of CNR1 mRNA; Streptozocin results in increased expression of CNR1 protein [Streptozocin co-treated with CNR1 protein] affects the expression of IGF1R protein; [Streptozocin co-treated with CNR1 protein] affects the phosphorylation of AKT1 protein; CNR1 protein promotes the reaction [Streptozocin results in decreased expression of BCL2 protein]; CNR1 protein promotes the reaction [Streptozocin results in decreased expression of CCND2 protein]; CNR1 protein promotes the reaction [Streptozocin results in decreased expression of INS1 protein]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of CNR1 mRNA]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of CNR1 protein] |
CTD |
PMID:26967640 PMID:30184259 PMID:30642005 PMID:30721768 PMID:31468622 |
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NCBI chr 4:33,923,171...33,948,831
Ensembl chr 4:33,924,593...33,948,831
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G |
Col1a1 |
collagen, type I, alpha 1 |
multiple interactions increases expression |
EXP |
[Dietary Fats co-treated with Streptozocin] results in increased expression of COL1A1 mRNA; Curcumin analog inhibits the reaction [Streptozocin results in increased expression of COL1A1 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of COL1A1 mRNA]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of COL1A1 mRNA] |
CTD |
PMID:28700904 PMID:29988851 |
|
NCBI chr11:94,827,050...94,843,868
Ensembl chr11:94,827,050...94,843,868
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G |
Col3a1 |
collagen, type III, alpha 1 |
multiple interactions increases expression |
EXP ISO |
[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of COL3A1 mRNA; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of COL3A1 mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of COL3A1 protein] INS1 protein inhibits the reaction [Streptozocin results in increased expression of COL3A1 protein] |
CTD |
PMID:29266779 PMID:29682576 PMID:39047806 |
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NCBI chr 1:45,350,698...45,388,866
Ensembl chr 1:45,350,698...45,388,866
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G |
Col4a1 |
collagen, type IV, alpha 1 |
decreases expression increases expression multiple interactions |
EXP ISO |
Streptozocin results in decreased expression of COL4A1 mRNA Streptozocin results in increased expression of COL4A1 mRNA benazepril inhibits the reaction [Streptozocin results in increased expression of COL4A1 mRNA]; MFN2 protein mutant form inhibits the reaction [Streptozocin promotes the reaction [TFAP2A protein binds to COL4A1 promoter]]; MFN2 protein mutant form inhibits the reaction [Streptozocin results in increased expression of COL4A1 mRNA]; Streptozocin promotes the reaction [TFAP2A protein binds to COL4A1 promoter] [fatostatin co-treated with Streptozocin] results in increased expression of COL4A1 mRNA |
CTD |
PMID:11798618 PMID:15496156 PMID:17582205 PMID:27997345 PMID:29420703 |
|
NCBI chr 8:11,248,423...11,362,889
Ensembl chr 8:11,248,423...11,362,826
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G |
Col4a2 |
collagen, type IV, alpha 2 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of COL4A2 mRNA MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of COL4A2 mRNA] |
CTD |
PMID:30642005 |
|
NCBI chr 8:11,362,878...11,499,287
Ensembl chr 8:11,362,805...11,499,287
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G |
Col4a3 |
collagen, type IV, alpha 3 |
multiple interactions increases expression |
ISO |
Zinc inhibits the reaction [Streptozocin results in increased expression of COL4A3 mRNA] |
CTD |
PMID:31009641 |
|
NCBI chr 1:82,564,647...82,699,778
Ensembl chr 1:82,564,642...82,699,780
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G |
Col4a4 |
collagen, type IV, alpha 4 |
multiple interactions increases expression |
EXP |
3-((6-(2-methoxyphenyl)pyrimidin-4-yl)amino)phenyl)methane sulfonamide inhibits the reaction [Streptozocin results in increased expression of COL4A4 mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of COL4A4 mRNA] |
CTD |
PMID:33631230 |
|
NCBI chr 1:82,426,140...82,564,570
Ensembl chr 1:82,426,144...82,564,570
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G |
Col6a1 |
collagen, type VI, alpha 1 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of COL6A1 protein Trientine inhibits the reaction [Streptozocin results in increased expression of COL6A1 protein] |
CTD |
PMID:19634143 |
|
NCBI chr10:76,544,626...76,561,869
Ensembl chr10:76,544,626...76,562,002
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G |
Col6a2 |
collagen, type VI, alpha 2 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of COL6A2 protein Trientine inhibits the reaction [Streptozocin results in increased expression of COL6A2 protein] |
CTD |
PMID:19634143 |
|
NCBI chr10:76,431,590...76,459,464
Ensembl chr10:76,431,596...76,459,464
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G |
Col6a3 |
collagen, type VI, alpha 3 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of COL6A3 protein Trientine inhibits the reaction [Streptozocin results in increased expression of COL6A3 protein] |
CTD |
PMID:19634143 |
|
NCBI chr 1:90,694,582...90,771,710
Ensembl chr 1:90,693,645...90,771,693
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G |
Col7a1 |
collagen, type VII, alpha 1 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of COL7A1 mRNA |
CTD |
PMID:33484791 |
|
NCBI chr 9:108,782,654...108,813,943
Ensembl chr 9:108,782,654...108,813,943
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G |
Cotl1 |
coactosin like F-actin binding protein 1 |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of COTL1 mRNA |
CTD |
PMID:25905778 |
|
NCBI chr 8:120,535,953...120,567,318
Ensembl chr 8:120,535,961...120,567,283
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G |
Cox17 |
cytochrome c oxidase assembly protein 17, copper chaperone |
affects expression |
EXP |
Streptozocin affects the expression of COX17 mRNA |
CTD |
PMID:18583417 |
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NCBI chr16:38,167,332...38,173,125
Ensembl chr16:38,167,353...38,182,659
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G |
Cox5b |
cytochrome c oxidase subunit 5B |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of COX5B mRNA; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of COX5B mRNA] |
CTD |
PMID:37337224 |
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NCBI chr 1:36,730,568...36,732,469
Ensembl chr 1:36,730,530...36,732,762
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G |
Cp |
ceruloplasmin |
multiple interactions decreases expression |
ISO |
caryophyllene inhibits the reaction [Streptozocin results in decreased expression of CP protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of CP protein] |
CTD |
PMID:26748309 |
|
NCBI chr 3:20,011,097...20,063,914
Ensembl chr 3:20,011,218...20,063,309
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G |
Cpeb2 |
cytoplasmic polyadenylation element binding protein 2 |
multiple interactions |
EXP |
[Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of CPEB2 mRNA]; [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of CPEB2 protein] |
CTD |
PMID:38282657 |
|
NCBI chr 5:43,382,692...43,447,067
Ensembl chr 5:43,390,513...43,447,067
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G |
Cpeb4 |
cytoplasmic polyadenylation element binding protein 4 |
multiple interactions |
EXP |
[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of CPEB4 mRNA; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of CPEB4 protein |
CTD |
PMID:38282657 |
|
NCBI chr11:31,820,911...31,885,635
Ensembl chr11:31,822,211...31,885,634
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G |
Cpt1a |
carnitine palmitoyltransferase 1a, liver |
increases expression multiple interactions |
ISO EXP |
Streptozocin results in increased expression of CPT1A mRNA [resveratrol co-treated with Streptozocin] results in decreased expression of CPT1A mRNA; vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of CPT1A mRNA] [Dietary Fats co-treated with Streptozocin] results in decreased expression of CPT1A mRNA; Acrylamide inhibits the reaction [Streptozocin results in increased expression of CPT1A mRNA]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of CPT1A mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of CPT1A protein] |
CTD |
PMID:16684804 PMID:25905778 PMID:29988851 PMID:34896238 PMID:39047806 |
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NCBI chr19:3,372,328...3,435,735
Ensembl chr19:3,372,334...3,435,733
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G |
Cpt2 |
carnitine palmitoyltransferase 2 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of CPT2 protein Trientine inhibits the reaction [Streptozocin results in increased expression of CPT2 protein] |
CTD |
PMID:21136691 |
|
NCBI chr 4:107,761,179...107,780,786
Ensembl chr 4:107,761,178...107,780,807
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G |
Creb1 |
cAMP responsive element binding protein 1 |
multiple interactions decreases phosphorylation |
ISO EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of CREB1 mRNA; Memantine inhibits the reaction [Streptozocin results in decreased phosphorylation of CREB1 protein]; xanthoceraside inhibits the reaction [Streptozocin results in decreased phosphorylation of CREB1 protein] [Streptozocin co-treated with Dietary Fats] results in increased expression of CREB1 protein; CREB1 protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein]; HDAC3 protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CREB1 protein]; MIR10A mRNA affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CREB1 protein] |
CTD |
PMID:20665664 PMID:23562514 PMID:27292126 |
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NCBI chr 1:64,571,963...64,643,707
Ensembl chr 1:64,571,804...64,643,707
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G |
Crebbp |
CREB binding protein |
decreases expression |
ISO |
Streptozocin results in decreased expression of CREBBP mRNA |
CTD |
PMID:25905778 |
|
NCBI chr16:3,899,198...4,031,864
Ensembl chr16:3,899,192...4,031,861
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G |
Crot |
carnitine O-octanoyltransferase |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of CROT mRNA [resveratrol co-treated with Streptozocin] results in decreased expression of CROT mRNA |
CTD |
PMID:25905778 |
|
NCBI chr 5:9,016,033...9,047,926
Ensembl chr 5:9,016,033...9,047,324
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G |
Crp |
C-reactive protein, pentraxin-related |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of CRP protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CRP protein] |
CTD |
PMID:33484791 |
|
NCBI chr 1:172,525,623...172,527,533
Ensembl chr 1:172,525,622...172,660,598
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G |
Cry1 |
cryptochrome circadian regulator 1 |
increases expression |
ISO |
Streptozocin results in increased expression of CRY1 mRNA |
CTD |
PMID:25905778 |
|
NCBI chr10:84,967,564...85,020,918
Ensembl chr10:84,967,564...85,020,928
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G |
Crybb3 |
crystallin, beta B3 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of CRYBB3 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CRYBB3 mRNA] |
CTD |
PMID:33484791 |
|
NCBI chr 5:113,223,705...113,230,102
Ensembl chr 5:113,223,705...113,229,450
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G |
Cryz |
crystallin, zeta |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of CRYZ protein Trientine inhibits the reaction [Streptozocin results in decreased expression of CRYZ protein] |
CTD |
PMID:19634143 |
|
NCBI chr 3:154,302,348...154,328,819
Ensembl chr 3:154,302,348...154,328,819
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G |
Csf1r |
colony stimulating factor 1 receptor |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of CSF1R mRNA |
CTD |
PMID:25905778 |
|
NCBI chr18:61,238,644...61,264,211
Ensembl chr18:61,233,670...61,265,221
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G |
Csn1s2a |
casein alpha s2-like A |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of CSN1S2A mRNA |
CTD |
PMID:33484791 |
|
NCBI chr 5:87,922,309...87,936,657
Ensembl chr 5:87,922,426...87,936,656
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G |
Csrp3 |
cysteine and glycine-rich protein 3 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of CSRP3 mRNA vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of CSRP3 mRNA] |
CTD |
PMID:16684804 |
|
NCBI chr 7:48,480,146...48,497,799
Ensembl chr 7:48,480,146...48,497,781
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G |
Cst3 |
cystatin C |
multiple interactions increases expression |
ISO |
[Streptozocin co-treated with Fructose] results in increased expression of CST3 protein; Glyburide inhibits the reaction [Streptozocin results in increased expression of CST3 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of CST3 protein]; Tropisetron inhibits the reaction [Streptozocin results in increased expression of CST3 protein] |
CTD |
PMID:30551545 PMID:33387473 |
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NCBI chr 2:148,713,642...148,717,432
Ensembl chr 2:148,713,642...148,717,612
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G |
Cstdc5 |
cystatin domain containing 5 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of CSTDC5 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CSTDC5 mRNA] |
CTD |
PMID:33484791 |
|
NCBI chr16:36,179,744...36,187,932
Ensembl chr16:36,179,744...36,188,110
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G |
Cth |
cystathionine gamma lyase |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] affects the expression of CTH mRNA |
CTD |
PMID:29127188 |
|
NCBI chr 3:157,599,885...157,630,718
Ensembl chr 3:157,599,885...157,630,714
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G |
Ctnnb1 |
catenin beta 1 |
multiple interactions increases phosphorylation |
EXP |
5-Methoxypsoralen inhibits the reaction [Streptozocin results in increased phosphorylation of CTNNB1 protein]; Tadalafil inhibits the reaction [Streptozocin results in increased phosphorylation of CTNNB1 protein] |
CTD |
PMID:34428446 |
|
NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573
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G |
Ctsd |
cathepsin D |
increases expression |
EXP |
Streptozocin results in increased expression of CTSD protein |
CTD |
PMID:28468961 |
|
NCBI chr 7:141,929,647...141,941,564
Ensembl chr 7:141,929,648...141,941,775
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G |
Ctsk |
cathepsin K |
increases expression multiple interactions |
ISO EXP |
Streptozocin results in increased expression of CTSK mRNA; Streptozocin results in increased expression of CTSK protein formononetin inhibits the reaction [Streptozocin results in increased expression of CTSK mRNA]; formononetin inhibits the reaction [Streptozocin results in increased expression of CTSK protein] |
CTD |
PMID:25617479 PMID:35315182 |
|
NCBI chr 3:95,406,521...95,416,698
Ensembl chr 3:95,406,567...95,416,673
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G |
Ctss |
cathepsin S |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of CTSS mRNA [resveratrol co-treated with Streptozocin] results in increased expression of CTSS mRNA; vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of CTSS mRNA] |
CTD |
PMID:16684804 PMID:25905778 |
|
NCBI chr 3:95,434,097...95,463,716
Ensembl chr 3:95,434,097...95,463,714
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G |
Cubn |
cubilin |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of CUBN protein; bicalutamide promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CUBN protein] |
CTD |
PMID:35151640 |
|
NCBI chr 2:13,281,149...13,496,687
Ensembl chr 2:13,281,149...13,496,624
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G |
Cxcl1 |
C-X-C motif chemokine ligand 1 |
multiple interactions |
ISO |
[Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in increased expression of CXCL1 protein]; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in increased expression of CXCL1 protein]] |
CTD |
PMID:36547818 |
|
NCBI chr 5:91,039,104...91,040,980
Ensembl chr 5:91,039,100...91,040,974
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G |
Cxcl12 |
C-X-C motif chemokine ligand 12 |
multiple interactions decreases expression |
EXP |
[Streptozocin co-treated with Oxygen deficiency] results in decreased expression of CXCL12 mRNA; CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of KLF15 protein]; CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CCN2 protein]; CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FN1 protein]; CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein]; KLF15 gene mutant form inhibits the reaction [CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CCN2 protein]]; KLF15 gene mutant form inhibits the reaction [CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FN1 protein]]; KLF15 gene mutant form inhibits the reaction [CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein]]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [[Streptozocin co-treated with Oxygen deficiency] results in decreased expression of CXCL12 mRNA] Streptozocin results in decreased expression of CXCL12 mRNA; Streptozocin results in decreased expression of CXCL12 protein |
CTD |
PMID:18227068 PMID:34310909 |
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NCBI chr 6:117,145,496...117,158,329
Ensembl chr 6:117,145,496...117,158,328
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G |
Cxcr4 |
C-X-C motif chemokine receptor 4 |
multiple interactions |
ISO |
[Streptozocin co-treated with Tobacco Smoke Pollution] results in increased expression of CXCR4 protein |
CTD |
PMID:30421503 |
|
NCBI chr 1:128,515,936...128,520,036
Ensembl chr 1:128,515,936...128,520,030
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G |
Cyb561 |
cytochrome b-561 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of CYB561 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CYB561 mRNA] |
CTD |
PMID:33484791 |
|
NCBI chr11:105,824,528...105,844,157
Ensembl chr11:105,824,528...105,844,162
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G |
Cyba |
cytochrome b-245, alpha polypeptide |
multiple interactions increases expression |
ISO |
[[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of CYBA mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in increased expression of CYBA protein; [Carbamazepine affects the susceptibility to [Dietary Fats co-treated with Streptozocin]] which results in decreased expression of CYBA mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of CYBA protein; [Resveratrol co-treated with Streptozocin] results in increased expression of CYBA mRNA; Bezafibrate inhibits the reaction [Streptozocin results in increased expression of CYBA mRNA]; candesartan inhibits the reaction [Streptozocin results in increased expression of CYBA mRNA] |
CTD |
PMID:12967931 PMID:16139267 PMID:25905778 PMID:35786680 |
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NCBI chr 8:123,151,510...123,159,679
Ensembl chr 8:123,151,515...123,159,669
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G |
Cybb |
cytochrome b-245, beta polypeptide |
increases expression multiple interactions |
EXP ISO |
Streptozocin results in increased expression of CYBB mRNA; Streptozocin results in increased expression of CYBB protein 2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of NOX2 mRNA]; [fatostatin co-treated with Streptozocin] results in increased expression of CYBB mRNA; [Streptozocin co-treated with Niacinamide] results in increased expression of NOX2 mRNA; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of NOX2 mRNA]; Telmisartan inhibits the reaction [Streptozocin results in increased expression of CYBB protein] [Streptozocin co-treated with Dietary Fats] results in increased expression of CYBB protein; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CYBB protein] |
CTD |
PMID:19957251 PMID:21381899 PMID:29420703 PMID:35085591 PMID:37120126 |
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NCBI chr X:9,301,493...9,354,005
Ensembl chr X:9,301,491...9,354,010
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G |
Cyc1 |
cytochrome c-1 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of CYC1 protein Trientine inhibits the reaction [Streptozocin results in increased expression of CYC1 protein] |
CTD |
PMID:19634143 |
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NCBI chr15:76,227,711...76,230,460
Ensembl chr15:76,227,723...76,230,460
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Cycs |
cytochrome c, somatic |
affects localization multiple interactions increases expression |
ISO EXP |
Streptozocin affects the localization of CYCS protein arjunolic acid inhibits the reaction [Streptozocin affects the localization of CYCS protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of CYCS mRNA]; morin inhibits the reaction [Streptozocin results in increased expression of CYCS mRNA]; Phosphocreatine inhibits the reaction [Streptozocin results in increased expression of CYCS protein]; Thioctic Acid inhibits the reaction [Streptozocin affects the localization of CYCS protein] Streptozocin results in increased expression of CYCS mRNA; Streptozocin results in increased expression of CYCS protein Metformin inhibits the reaction [Streptozocin affects the localization of CYCS protein]; phillyrin inhibits the reaction [Streptozocin affects the localization of CYCS protein] |
CTD |
PMID:19682444 PMID:19951573 PMID:34455488 PMID:34649470 PMID:35414346 PMID:36462176 More...
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NCBI chr 6:50,539,543...50,543,549
Ensembl chr 6:50,539,543...50,543,518
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G |
Cyp11b2 |
cytochrome P450, family 11, subfamily b, polypeptide 2 |
increases expression |
ISO |
Streptozocin results in increased expression of CYP11B2 mRNA; Streptozocin results in increased expression of CYP11B2 protein |
CTD |
PMID:16043663 |
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NCBI chr15:74,722,467...74,728,080
Ensembl chr15:74,722,467...74,728,167
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
multiple interactions increases expression |
EXP ISO |
Metformin promotes the reaction [Streptozocin results in increased expression of CYP1A1 mRNA]; Streptozocin promotes the reaction [Dietary Fats results in decreased expression of CYP1A1 mRNA] [resveratrol co-treated with Streptozocin] results in increased expression of CYP1A1 mRNA |
CTD |
PMID:22342832 PMID:25905778 PMID:29382564 |
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NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
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G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
decreases expression increases expression multiple interactions |
EXP ISO |
Streptozocin results in decreased expression of CYP1A2 protein Streptozocin results in increased expression of CYP1A2 protein [resveratrol co-treated with Streptozocin] results in decreased expression of CYP1A2 mRNA; [Streptozocin results in increased expression of CYP1A2 protein] which results in increased metabolism of Diazinon Streptozocin results in decreased expression of CYP1A2 mRNA [Streptozocin co-treated with Dietary Fats] results in decreased expression of CYP1A2 mRNA |
CTD |
PMID:12700423 PMID:17442507 PMID:25905778 PMID:29127188 |
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NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986
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G |
Cyp26a1 |
cytochrome P450, family 26, subfamily a, polypeptide 1 |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of CYP26A1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr19:37,686,186...37,689,984
Ensembl chr19:37,686,246...37,689,984
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G |
Cyp26b1 |
cytochrome P450, family 26, subfamily b, polypeptide 1 |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of CYP26B1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 6:84,548,396...84,570,890
Ensembl chr 6:84,548,396...84,570,890
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G |
Cyp27a1 |
cytochrome P450, family 27, subfamily a, polypeptide 1 |
multiple interactions |
EXP |
[Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP27A1 mRNA |
CTD |
PMID:29382564 |
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NCBI chr 1:74,752,311...74,777,056
Ensembl chr 1:74,752,733...74,777,051
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G |
Cyp2a22 |
cytochrome P450, family 2, subfamily a, polypeptide 22 |
decreases expression multiple interactions |
ISO EXP |
Streptozocin results in decreased expression of CYP2A1 mRNA [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of CYP2A22 mRNA |
CTD |
PMID:25905778 PMID:33484791 |
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NCBI chr 7:26,631,564...26,638,838
Ensembl chr 7:26,631,056...26,638,809
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G |
Cyp2a4 |
cytochrome P450, family 2, subfamily a, polypeptide 4 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of CYP2A4 mRNA |
CTD |
PMID:33484791 |
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NCBI chr 7:26,006,617...26,014,513
Ensembl chr 7:26,006,594...26,014,513
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G |
Cyp2b10 |
cytochrome P450, family 2, subfamily b, polypeptide 10 |
multiple interactions increases expression |
EXP |
Berberine inhibits the reaction [Streptozocin results in increased expression of CYP2B10 mRNA]; Streptozocin promotes the reaction [Dietary Fats results in decreased expression of CYP2B10 mRNA] |
CTD |
PMID:22342832 PMID:29382564 |
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NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049
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G |
Cyp2b13 |
cytochrome P450, family 2, subfamily b, polypeptide 13 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of CYP2B13 mRNA |
CTD |
PMID:29127188 |
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NCBI chr 7:25,760,813...25,795,622
Ensembl chr 7:25,760,922...25,795,622
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G |
Cyp2b9 |
cytochrome P450, family 2, subfamily b, polypeptide 9 |
multiple interactions increases expression |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of CYP2B9 mRNA; Berberine promotes the reaction [Streptozocin results in increased expression of CYP2B9 mRNA]; Metformin promotes the reaction [Streptozocin results in increased expression of CYP2B9 mRNA] |
CTD |
PMID:22342832 PMID:29127188 |
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NCBI chr 7:25,872,775...25,910,086
Ensembl chr 7:25,872,836...25,910,086
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G |
Cyp2c39 |
cytochrome P450, family 2, subfamily c, polypeptide 39 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of CYP2C39 mRNA |
CTD |
PMID:29127188 |
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NCBI chr19:39,335,790...39,558,012
Ensembl chr19:39,499,306...39,556,973
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G |
Cyp2c52-ps |
cytochrome P450, family 2, subfamily c, polypeptide 52, pseudogene |
multiple interactions |
ISO |
[Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP2C11 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP2C11 protein |
CTD |
PMID:24815820 |
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NCBI chr19:38,965,106...38,992,071
Ensembl chr19:38,965,091...38,991,733
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G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
decreases expression increases expression multiple interactions |
EXP ISO |
Streptozocin results in decreased expression of CYP2E1 protein Streptozocin results in increased expression of CYP2E1 mRNA; Streptozocin results in increased expression of CYP2E1 protein [Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased activity of CYP2E1 protein |
CTD |
PMID:11752103 PMID:12700423 PMID:14693714 PMID:24815820 PMID:25905778 |
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NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900
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G |
Cyp2j9 |
cytochrome P450, family 2, subfamily j, polypeptide 9 |
increases expression |
ISO |
Streptozocin results in increased expression of CYP2J4 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 4:96,456,661...96,480,748
Ensembl chr 4:96,456,666...96,479,815
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G |
Cyp3a11 |
cytochrome P450, family 3, subfamily a, polypeptide 11 |
multiple interactions increases expression |
EXP |
[Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP3A11 mRNA; Berberine inhibits the reaction [Streptozocin results in increased expression of CYP3A11 mRNA] |
CTD |
PMID:22342832 PMID:29382564 |
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NCBI chr 5:145,791,417...145,816,664
Ensembl chr 5:145,791,236...145,816,774
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G |
Cyp3a16 |
cytochrome P450, family 3, subfamily a, polypeptide 16 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of CYP3A16 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CYP3A16 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 5:145,373,119...145,406,550
Ensembl chr 5:145,373,119...145,406,533
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G |
Cyp3a57 |
cytochrome P450, family 3, subfamily a, polypeptide 57 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of CYP3A57 mRNA |
CTD |
PMID:33484791 |
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NCBI chr 5:145,281,959...145,327,736
Ensembl chr 5:145,282,089...145,327,736
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G |
Cyp3a63-ps |
cytochrome P450, family 3, subfamily a, member 63, pseudogene |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of CYP3A63-PS mRNA |
CTD |
PMID:33484791 |
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NCBI chr 5:145,560,905...145,584,717
Ensembl chr 5:145,560,902...145,570,803
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G |
Cyp4a10 |
cytochrome P450, family 4, subfamily a, polypeptide 10 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of CYP4A10 mRNA Berberine inhibits the reaction [Streptozocin results in increased expression of CYP4A10 mRNA] |
CTD |
PMID:22342832 |
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NCBI chr 4:115,375,484...115,390,846
Ensembl chr 4:115,375,461...115,390,846
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G |
Cyp4a12b |
cytochrome P450, family 4, subfamily a, polypeptide 12B |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of CYP4A1 mRNA [Dietary Fats co-treated with Streptozocin] results in increased expression of CYP4A1 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of CYP4A1 protein; [resveratrol co-treated with Streptozocin] results in decreased expression of CYP4A1 mRNA |
CTD |
PMID:24815820 PMID:25905778 |
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NCBI chr 4:115,268,821...115,296,231
Ensembl chr 4:115,268,821...115,296,231
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G |
Cyp4a14 |
cytochrome P450, family 4, subfamily a, polypeptide 14 |
multiple interactions increases expression |
EXP |
Berberine inhibits the reaction [Streptozocin results in increased expression of CYP4A14 mRNA] |
CTD |
PMID:22342832 PMID:23319174 |
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NCBI chr 4:115,343,397...115,353,355
Ensembl chr 4:115,343,397...115,353,339
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G |
Cyp4f14 |
cytochrome P450, family 4, subfamily f, polypeptide 14 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of CYP4F14 mRNA |
CTD |
PMID:29127188 |
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NCBI chr17:33,122,331...33,136,353
Ensembl chr17:33,124,044...33,136,316
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G |
Cyp7a1 |
cytochrome P450, family 7, subfamily a, polypeptide 1 |
increases expression multiple interactions |
ISO EXP |
Streptozocin results in increased expression of CYP7A1 mRNA [Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 protein; Acrylamide inhibits the reaction [Streptozocin results in increased expression of CYP7A1 mRNA] [Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 protein; Fungal Polysaccharides inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 mRNA]; Fungal Polysaccharides inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 protein]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 mRNA]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 protein] |
CTD |
PMID:10393316 PMID:29382564 PMID:31100278 PMID:34896238 |
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NCBI chr 4:6,265,612...6,275,632
Ensembl chr 4:6,265,612...6,275,633
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G |
Cyp7b1 |
cytochrome P450, family 7, subfamily b, polypeptide 1 |
multiple interactions |
EXP |
[Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7B1 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of CYP7B1 mRNA |
CTD |
PMID:29127188 PMID:29382564 |
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NCBI chr 3:18,126,108...18,298,054
Ensembl chr 3:18,126,114...18,297,502
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G |
Cyp8b1 |
cytochrome P450, family 8, subfamily b, polypeptide 1 |
multiple interactions increases expression |
ISO EXP |
[resveratrol co-treated with Streptozocin] results in decreased expression of CYP8B1 mRNA; INS1 protein inhibits the reaction [Streptozocin results in increased expression of CYP8B1 mRNA]; Streptozocin inhibits the reaction [resveratrol results in increased expression of CYP8B1 mRNA] Streptozocin results in increased expression of CYP8B1 mRNA; Streptozocin results in increased expression of CYP8B1 protein [Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP8B1 mRNA |
CTD |
PMID:10393316 PMID:25905778 PMID:29382564 |
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NCBI chr 9:121,743,422...121,745,371
Ensembl chr 9:121,743,422...121,745,371
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G |
Cysltr1 |
cysteinyl leukotriene receptor 1 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of CYSLTR1 mRNA; Streptozocin results in increased expression of CYSLTR1 protein montelukast inhibits the reaction [Streptozocin results in increased expression of CYSLTR1 mRNA]; montelukast inhibits the reaction [Streptozocin results in increased expression of CYSLTR1 protein] |
CTD |
PMID:27702591 |
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NCBI chr X:105,617,952...105,647,329
Ensembl chr X:105,617,952...105,647,285
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G |
Cyyr1 |
cysteine and tyrosine-rich protein 1 |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of CYYR1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr16:85,247,245...85,347,793
Ensembl chr16:85,218,421...85,350,285
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G |
Dao |
D-amino acid oxidase |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of DAO protein Trientine inhibits the reaction [Streptozocin results in increased expression of DAO protein] |
CTD |
PMID:19634143 |
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NCBI chr 5:114,137,696...114,163,736
Ensembl chr 5:114,141,764...114,163,743
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G |
Dapk1 |
death associated protein kinase 1 |
decreases expression |
ISO |
Streptozocin results in decreased expression of DAPK1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr13:60,749,506...60,911,005
Ensembl chr13:60,749,761...60,911,005
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G |
Dapl1 |
death associated protein-like 1 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of DAPL1 mRNA |
CTD |
PMID:33484791 |
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NCBI chr 2:59,314,997...59,335,364
Ensembl chr 2:59,314,997...59,335,364
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G |
Dbn1 |
drebrin 1 |
decreases expression |
ISO |
Streptozocin results in decreased expression of DBN1 protein |
CTD |
PMID:23333261 |
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NCBI chr13:55,621,241...55,635,874
Ensembl chr13:55,621,242...55,635,924
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G |
Dbt |
dihydrolipoamide branched chain transacylase E2 |
affects expression |
EXP |
Streptozocin affects the expression of DBT mRNA |
CTD |
PMID:18583417 |
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NCBI chr 3:116,306,776...116,343,630
Ensembl chr 3:116,306,719...116,343,630
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G |
Dcc |
DCC netrin 1 receptor |
multiple interactions increases expression |
EXP |
NTN1 protein promotes the reaction [Streptozocin results in increased expression of DCC mRNA]; NTN1 protein promotes the reaction [Streptozocin results in increased expression of DCC protein] Streptozocin results in increased expression of DCC mRNA; Streptozocin results in increased expression of DCC protein |
CTD |
PMID:29059224 |
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NCBI chr18:71,386,703...72,484,299
Ensembl chr18:71,386,705...72,484,140
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
increases expression multiple interactions increases expression |
EXP ISO |
Streptozocin results in increased expression of DDIT3; Streptozocin results in increased expression of DDIT3 mRNA; Streptozocin results in increased expression of DDIT3 protein [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of DDIT3 mRNA]; [Streptozocin co-treated with bisphenol A] results in increased expression of DDIT3 protein; [Streptozocin co-treated with Ethinyl Estradiol] results in increased expression of DDIT3 mRNA; [Streptozocin co-treated with Ethinyl Estradiol] results in increased expression of DDIT3 protein; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of DDIT3 mRNA; [Streptozocin co-treated with octylphenol] results in increased expression of DDIT3 mRNA; [Streptozocin co-treated with octylphenol] results in increased expression of DDIT3 protein; FGF21 protein affects the reaction [Streptozocin results in increased expression of DDIT3]; Streptozocin promotes the reaction [bisphenol A results in increased expression of DDIT3 mRNA]; sulforaphane inhibits the reaction [Streptozocin results in increased expression of DDIT3 protein] 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of DDIT3 protein]; [Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of DDIT3 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of DDIT3 mRNA; Bilirubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of DDIT3 mRNA]; Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of DDIT3 protein]; Vitamin B 12 inhibits the reaction [Streptozocin results in increased expression of DDIT3 protein] streptozocin increases expression of Ddit3 protein in heart |
CTD RGD |
PMID:23499715 PMID:24967692 PMID:29935216 PMID:30980806 PMID:34801538 PMID:37054934 PMID:38049026 PMID:38282657 PMID:36044268 More...
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RGD:156430337 |
NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157 Ensembl chr10:127,126,643...127,132,157
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G |
Ddit4 |
DNA-damage-inducible transcript 4 |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of DDIT4 mRNA |
CTD |
PMID:25905778 |
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NCBI chr10:59,785,497...59,787,592
Ensembl chr10:59,785,491...59,787,656
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G |
Decr1 |
2,4-dienoyl CoA reductase 1, mitochondrial |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of DECR1 mRNA vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of DECR1 mRNA] |
CTD |
PMID:16684804 |
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NCBI chr 4:15,917,240...15,945,377
Ensembl chr 4:15,917,240...15,945,507
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G |
Derl1 |
Der1-like domain family, member 1 |
multiple interactions increases expression |
ISO |
4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of DERL1 protein] |
CTD |
PMID:30980806 |
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NCBI chr15:57,732,898...57,755,814
Ensembl chr15:57,732,898...57,755,844
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G |
Derl3 |
Der1-like domain family, member 3 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of DERL3 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of DERL3 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr10:75,729,232...75,731,775
Ensembl chr10:75,729,247...75,731,775
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G |
Des |
desmin |
multiple interactions increases expression |
ISO |
Mycophenolic Acid inhibits the reaction [Streptozocin results in increased expression of DES protein]; Valsartan inhibits the reaction [Streptozocin results in increased expression of DES protein] |
CTD |
PMID:12197670 PMID:17624267 |
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NCBI chr 1:75,336,936...75,345,223
Ensembl chr 1:75,336,973...75,345,223
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G |
Dgat1 |
diacylglycerol O-acyltransferase 1 |
multiple interactions |
EXP |
[Dietary Fats co-treated with Streptozocin] results in increased expression of DGAT1 mRNA; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of DGAT1 mRNA] |
CTD |
PMID:33812996 |
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NCBI chr15:76,386,215...76,396,167
Ensembl chr15:76,386,215...76,396,153
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G |
Dgat2 |
diacylglycerol O-acyltransferase 2 |
multiple interactions |
ISO |
[[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in decreased expression of DGAT2 mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of DGAT2 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of DGAT2 mRNA |
CTD |
PMID:35786680 |
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NCBI chr 7:98,802,870...98,831,920
Ensembl chr 7:98,802,865...98,831,926
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G |
Dgkh |
diacylglycerol kinase, eta |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of DGKH mRNA |
CTD |
PMID:20665664 |
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NCBI chr14:78,796,789...78,970,169
Ensembl chr14:78,796,190...78,970,216
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G |
Dhrs7 |
dehydrogenase/reductase 7 |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in decreased expression of DHRS7 mRNA |
CTD |
PMID:25905778 |
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NCBI chr12:72,697,127...72,711,678
Ensembl chr12:72,697,127...72,711,683
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G |
Dhrs9 |
dehydrogenase/reductase 9 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of DHRS9 mRNA |
CTD |
PMID:29127188 |
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NCBI chr 2:69,210,806...69,233,430
Ensembl chr 2:69,210,789...69,234,877
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G |
Diablo |
diablo, IAP-binding mitochondrial protein |
multiple interactions |
EXP |
[Streptozocin co-treated with NQO1 protein mutant form] results in increased secretion of DIABLO protein |
CTD |
PMID:23458895 |
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NCBI chr 5:123,649,393...123,664,825
Ensembl chr 5:123,647,828...123,662,239
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G |
Dio1 |
deiodinase, iodothyronine, type I |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in decreased expression of DIO1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 4:107,148,662...107,164,365
Ensembl chr 4:107,148,662...107,164,366
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G |
Dio3 |
deiodinase, iodothyronine type III |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of DIO3 mRNA |
CTD |
PMID:33484791 |
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NCBI chr12:110,245,664...110,247,531
Ensembl chr12:110,245,502...110,247,531
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G |
Dlat |
dihydrolipoamide S-acetyltransferase |
multiple interactions increases expression |
ISO |
Trientine inhibits the reaction [Streptozocin results in increased expression of DLAT protein] |
CTD |
PMID:21136691 |
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NCBI chr 9:50,545,933...50,571,080
Ensembl chr 9:50,545,933...50,571,080
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G |
Dld |
dihydrolipoamide dehydrogenase |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of DLD protein Trientine inhibits the reaction [Streptozocin results in increased expression of DLD protein] |
CTD |
PMID:21136691 |
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NCBI chr12:31,381,561...31,401,470
Ensembl chr12:31,381,276...31,401,452
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G |
Dlg4 |
discs large MAGUK scaffold protein 4 |
multiple interactions decreases expression |
ISO |
Ibuprofen inhibits the reaction [Streptozocin results in decreased expression of DLG4 protein]; Memantine inhibits the reaction [Streptozocin results in decreased expression of DLG4 protein] |
CTD |
PMID:24333387 |
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NCBI chr11:69,908,029...69,938,107
Ensembl chr11:69,907,768...69,938,348
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G |
Dlgap2 |
DLG associated protein 2 |
multiple interactions decreases expression |
ISO |
Ibuprofen inhibits the reaction [Streptozocin results in decreased expression of DLGAP2 mRNA]; Memantine inhibits the reaction [Streptozocin results in decreased expression of DLGAP2 mRNA] |
CTD |
PMID:24333387 |
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NCBI chr 8:14,145,793...14,903,426
Ensembl chr 8:14,145,865...14,897,680
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G |
Dlst |
dihydrolipoamide S-succinyltransferase |
multiple interactions increases expression |
ISO |
Trientine inhibits the reaction [Streptozocin results in increased expression of DLST protein] |
CTD |
PMID:19634143 PMID:21136691 |
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NCBI chr12:85,157,597...85,180,865
Ensembl chr12:85,157,607...85,181,619
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G |
Dmbt1 |
deleted in malignant brain tumors 1 |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of DMBT1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 7:130,633,787...130,723,357
Ensembl chr 7:130,633,776...130,723,357
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G |
Dnah5 |
dynein, axonemal, heavy chain 5 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of DNAH5 mRNA |
CTD |
PMID:33484791 |
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NCBI chr15:28,155,000...28,472,191
Ensembl chr15:28,203,898...28,472,198
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G |
Dnm1l |
dynamin 1-like |
increases expression multiple interactions |
ISO EXP |
Streptozocin results in increased expression of DNM1L protein ferulic acid inhibits the reaction [Streptozocin results in increased expression of DNM1L protein] [Dietary Fats co-treated with Streptozocin] results in increased expression of DNM1L mRNA |
CTD |
PMID:31029786 PMID:33812996 |
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NCBI chr16:16,130,092...16,176,863
Ensembl chr16:16,130,094...16,176,823
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G |
Dnmt1 |
DNA methyltransferase 1 |
multiple interactions decreases expression |
EXP ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of DNMT1 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of DNMT1 protein; Folic Acid deficiency promotes the reaction [Streptozocin results in decreased expression of DNMT1 mRNA]; Folic Acid inhibits the reaction [Streptozocin results in decreased expression of DNMT1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in decreased expression of DNMT1 mRNA] [Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in decreased expression of DNMT1 mRNA]; [Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in decreased expression of DNMT1 protein]; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in decreased expression of DNMT1 mRNA]]; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in decreased expression of DNMT1 protein]] |
CTD |
PMID:28422052 PMID:29127188 PMID:36547818 |
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NCBI chr 9:20,818,501...20,871,084
Ensembl chr 9:20,818,505...20,871,184
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G |
Dnmt3a |
DNA methyltransferase 3A |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of DNMT3A mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of DNMT3A protein |
CTD |
PMID:29127188 |
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NCBI chr12:3,851,559...3,964,442
Ensembl chr12:3,856,007...3,964,443
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G |
Dnmt3b |
DNA methyltransferase 3B |
multiple interactions increases expression |
EXP ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of DNMT3B mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of DNMT3B protein Streptozocin results in increased expression of DNMT3B mRNA |
CTD |
PMID:29127188 PMID:37081038 |
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NCBI chr 2:153,491,332...153,529,650
Ensembl chr 2:153,491,370...153,529,650
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G |
Dpp4 |
dipeptidylpeptidase 4 |
increases response to substance decreases activity decreases expression increases expression |
ISO |
DPP4 results in increased susceptibility to Streptozocin Streptozocin results in decreased activity of DPP4 protein Streptozocin results in decreased expression of DPP4 protein Streptozocin results in increased expression of DPP4 mRNA |
CTD |
PMID:16045816 PMID:18931022 |
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NCBI chr 2:62,160,417...62,242,635
Ensembl chr 2:62,160,417...62,242,575
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G |
Drd1 |
dopamine receptor D1 |
increases phosphorylation multiple interactions |
ISO |
Streptozocin results in increased phosphorylation of DRD1 protein tempol inhibits the reaction [Streptozocin results in increased phosphorylation of DRD1 protein] |
CTD |
PMID:16478977 |
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NCBI chr13:54,205,202...54,209,677
Ensembl chr13:54,205,202...54,209,724
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G |
Ece1 |
endothelin converting enzyme 1 |
multiple interactions increases expression |
ISO |
Triterpenes inhibits the reaction [Streptozocin results in increased expression of ECE1 mRNA] |
CTD |
PMID:19000375 |
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NCBI chr 4:137,589,548...137,692,540
Ensembl chr 4:137,589,548...137,692,540
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G |
Echs1 |
enoyl Coenzyme A hydratase, short chain, 1, mitochondrial |
increases expression |
ISO |
Streptozocin results in increased expression of ECHS1 protein |
CTD |
PMID:21136691 |
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NCBI chr 7:139,685,623...139,696,334
Ensembl chr 7:139,685,623...139,696,389
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G |
Edaradd |
EDAR associated via death domain |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of EDARADD mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of EDARADD mRNA] |
CTD |
PMID:33484791 |
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NCBI chr13:12,486,090...12,535,413
Ensembl chr13:12,487,513...12,535,319
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G |
Edem1 |
ER degradation enhancer, mannosidase alpha-like 1 |
increases expression |
ISO |
Streptozocin results in increased expression of EDEM1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 6:108,800,984...108,836,317
Ensembl chr 6:108,805,602...108,836,317
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G |
Edem3 |
ER degradation enhancer, mannosidase alpha-like 3 |
multiple interactions |
EXP |
[Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of EDEM3 mRNA]; [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of EDEM3 protein]; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of EDEM3 mRNA; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of EDEM3 protein |
CTD |
PMID:38282657 |
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NCBI chr 1:151,631,099...151,698,079
Ensembl chr 1:151,631,122...151,697,802
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G |
Edn1 |
endothelin 1 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of EDN1 mRNA; Streptozocin results in increased expression of EDN1 protein Bezafibrate inhibits the reaction [Streptozocin results in increased expression of EDN1 mRNA]; Triterpenes inhibits the reaction [Streptozocin results in increased expression of EDN1 protein] diphenyleneiodonium inhibits the reaction [Streptozocin promotes the reaction [EDN1 protein results in increased chemical synthesis of Inositol 1,4,5-Trisphosphate]]; Streptozocin promotes the reaction [EDN1 protein results in increased chemical synthesis of Inositol 1,4,5-Trisphosphate] |
CTD |
PMID:12458661 PMID:12967931 PMID:19000375 PMID:20691780 |
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NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466
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G |
Efna3 |
ephrin A3 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of EFNA3 mRNA |
CTD |
PMID:33484791 |
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NCBI chr 3:89,221,200...89,231,359
Ensembl chr 3:89,221,206...89,230,272
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G |
Efnb2 |
ephrin B2 |
affects expression |
EXP |
Streptozocin affects the expression of EFNB2 mRNA |
CTD |
PMID:26073000 |
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NCBI chr 8:8,667,235...8,711,242
Ensembl chr 8:8,667,434...8,711,242
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G |
Egfr |
epidermal growth factor receptor |
increases expression |
ISO |
Streptozocin results in increased expression of EGFR mRNA |
CTD |
PMID:37081038 |
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NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158
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G |
Ehhadh |
enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase |
increases expression |
ISO |
Streptozocin results in increased expression of EHHADH mRNA |
CTD |
PMID:25905778 |
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NCBI chr16:21,580,035...21,606,589
Ensembl chr16:21,580,037...21,606,557
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G |
Eif2ak3 |
eukaryotic translation initiation factor 2 alpha kinase 3 |
multiple interactions increases phosphorylation |
EXP ISO |
[Dietary Fats co-treated with Streptozocin] results in increased expression of EIF2AK3 protein; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of EIF2AK3 protein] [Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of EIF2AK3 protein; Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of EIF2AK3 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of EIF2AK3 protein]; Vitamin B 12 inhibits the reaction [Streptozocin results in increased phosphorylation of EIF2AK3 protein] streptozocin increases phosphorylation of Eif2ak3 protein in heart |
CTD RGD |
PMID:33812996 PMID:34801538 PMID:38049026 PMID:36044268 |
RGD:156430337 |
NCBI chr 6:70,821,468...70,882,225
Ensembl chr 6:70,821,499...70,882,229
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G |
Eif2s1 |
eukaryotic translation initiation factor 2, subunit 1 alpha |
multiple interactions |
EXP |
[Dietary Fats co-treated with Streptozocin] results in increased phosphorylation of EIF2S1 protein; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased phosphorylation of EIF2S1 protein] |
CTD |
PMID:33812996 |
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NCBI chr12:78,908,846...78,933,784
Ensembl chr12:78,908,593...78,933,784
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G |
Eif4ebp1 |
eukaryotic translation initiation factor 4E binding protein 1 |
multiple interactions increases expression |
ISO |
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of EIF4EBP1 mRNA] |
CTD |
PMID:16684804 |
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NCBI chr 8:27,750,355...27,765,684
Ensembl chr 8:27,750,357...27,766,702
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G |
Elk1 |
ELK1, member of ETS oncogene family |
increases phosphorylation |
ISO |
Streptozocin results in increased phosphorylation of ELK1 protein |
CTD |
PMID:12642375 |
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NCBI chr X:20,799,634...20,816,847
Ensembl chr X:20,799,634...20,816,847
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G |
Elovl7 |
ELOVL fatty acid elongase 7 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of ELOVL7 mRNA |
CTD |
PMID:29127188 |
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NCBI chr13:108,350,860...108,423,643
Ensembl chr13:108,350,938...108,422,217
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G |
Eno1 |
enolase 1, alpha non-neuron |
increases expression |
ISO |
Streptozocin results in increased expression of ENO1 protein |
CTD |
PMID:24924950 |
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NCBI chr 4:150,321,165...150,333,336
Ensembl chr 4:150,321,178...150,333,336 Ensembl chr18:150,321,178...150,333,336
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G |
Eno2 |
enolase 2, gamma neuronal |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of ENO2 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ENO2 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 6:124,737,018...124,746,489
Ensembl chr 6:124,737,016...124,746,636
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G |
Enpep |
glutamyl aminopeptidase |
multiple interactions increases activity |
ISO EXP |
[resveratrol co-treated with Streptozocin] results in decreased expression of ENPEP mRNA Streptozocin results in increased activity of ENPEP protein |
CTD |
PMID:25905778 PMID:28468961 |
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NCBI chr 3:129,062,826...129,126,398
Ensembl chr 3:129,062,824...129,126,369
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G |
Enpp2 |
ectonucleotide pyrophosphatase/phosphodiesterase 2 |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in decreased expression of ENPP2 mRNA |
CTD |
PMID:25905778 |
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NCBI chr15:54,702,297...54,816,284
Ensembl chr15:54,702,297...54,816,288
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G |
Ep300 |
E1A binding protein p300 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of EP300 mRNA 3-aminobenzamide inhibits the reaction [Streptozocin results in increased expression of EP300 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of EP300 mRNA] |
CTD |
PMID:22228707 |
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NCBI chr15:81,470,329...81,536,273
Ensembl chr15:81,469,552...81,536,278
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G |
Epcam |
epithelial cell adhesion molecule |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of EPCAM mRNA |
CTD |
PMID:25905778 |
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NCBI chr17:87,943,407...87,958,555
Ensembl chr17:87,943,407...87,958,557
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G |
Ephx1 |
epoxide hydrolase 1, microsomal |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of EPHX1 protein Trientine inhibits the reaction [Streptozocin results in increased expression of EPHX1 protein] |
CTD |
PMID:19634143 |
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NCBI chr 1:180,817,121...180,845,134
Ensembl chr 1:180,803,775...180,848,469
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G |
Ephx2 |
epoxide hydrolase 2, cytoplasmic |
increases expression multiple interactions decreases response to substance |
ISO EXP |
Streptozocin results in increased expression of EPHX2 protein EPHX2 gene mutant form inhibits the reaction [Streptozocin results in increased activity of RELA protein]; EPHX2 gene mutant form inhibits the reaction [Streptozocin results in increased secretion of CCL2 protein] EPHX2 gene mutant form results in decreased susceptibility to Streptozocin |
CTD |
PMID:21832210 PMID:23611540 |
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NCBI chr14:66,321,821...66,361,971
Ensembl chr14:66,321,823...66,361,949
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G |
Epo |
erythropoietin |
multiple interactions decreases expression increases expression |
ISO |
[Dietary Fats co-treated with Streptozocin] results in decreased expression of EPO protein; dapagliflozin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of EPO protein]; Enalapril inhibits the reaction [Streptozocin results in increased expression of EPO mRNA]; Simvastatin inhibits the reaction [Streptozocin results in decreased expression of EPO protein]; Simvastatin inhibits the reaction [Streptozocin results in increased expression of EPO mRNA] |
CTD |
PMID:19958114 PMID:20821229 PMID:34391751 |
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NCBI chr 5:137,481,282...137,484,078
Ensembl chr 5:137,481,282...137,531,504
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G |
Epor |
erythropoietin receptor |
multiple interactions decreases expression increases expression |
ISO |
Enalapril inhibits the reaction [Streptozocin results in increased expression of EPOR mRNA]; Enalapril inhibits the reaction [Streptozocin results in increased expression of EPOR protein]; Simvastatin inhibits the reaction [Streptozocin results in decreased expression of EPOR protein]; Simvastatin inhibits the reaction [Streptozocin results in increased expression of EPOR mRNA] Streptozocin results in increased expression of EPOR mRNA; Streptozocin results in increased expression of EPOR protein |
CTD |
PMID:19958114 PMID:20821229 |
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NCBI chr 9:21,870,193...21,874,915
Ensembl chr 9:21,870,193...21,874,802
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G |
Ercc1 |
excision repair cross-complementing rodent repair deficiency, complementation group 1 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of ERCC1 mRNA; Streptozocin results in increased expression of ERCC1 protein 3-aminobenzamide inhibits the reaction [Streptozocin results in increased expression of ERCC1 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of ERCC1 mRNA] |
CTD |
PMID:22228707 |
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NCBI chr 7:19,079,016...19,090,449
Ensembl chr 7:19,078,703...19,090,449
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G |
Ercc4 |
excision repair cross-complementing rodent repair deficiency, complementation group 4 |
multiple interactions increases expression |
ISO |
3-aminobenzamide inhibits the reaction [Streptozocin results in increased expression of ERCC4 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of ERCC4 mRNA] Streptozocin results in increased expression of ERCC4 mRNA; Streptozocin results in increased expression of ERCC4 protein |
CTD |
PMID:22228707 |
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NCBI chr16:12,927,600...12,969,873
Ensembl chr16:12,927,548...12,968,481
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G |
Ermap |
erythroblast membrane-associated protein |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of ERMAP mRNA |
CTD |
PMID:33484791 |
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NCBI chr 4:119,032,654...119,047,210
Ensembl chr 4:119,032,654...119,047,208
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G |
Ern1 |
endoplasmic reticulum to nucleus signalling 1 |
multiple interactions increases expression |
ISO EXP |
4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of ERN1 protein modified form]; [Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of ERN1 protein; Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of ERN1 protein] [Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of ERN1 protein; aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of ERN1 protein] |
CTD |
PMID:20399799 PMID:34801538 PMID:35961541 |
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NCBI chr11:106,285,474...106,378,701
Ensembl chr11:106,285,476...106,378,678
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G |
Ern2 |
endoplasmic reticulum to nucleus signalling 2 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of ERN2 protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ERN2 protein] |
CTD |
PMID:33484791 |
|
NCBI chr 7:121,769,116...121,785,454
Ensembl chr 7:121,769,116...121,785,430
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G |
Esr1 |
estrogen receptor 1 (alpha) |
multiple interactions decreases expression increases expression |
EXP ISO |
bisphenol A inhibits the reaction [Streptozocin results in decreased expression of ESR1 mRNA]; Ethinyl Estradiol inhibits the reaction [Streptozocin results in decreased expression of ESR1 mRNA]; octylphenol inhibits the reaction [Streptozocin results in decreased expression of ESR1 mRNA] [Streptozocin co-treated with Tobacco Smoke Pollution] results in increased expression of ESR1 protein Streptozocin results in increased expression of ESR1 |
CTD |
PMID:24781736 PMID:30421503 PMID:32469605 |
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NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614
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G |
Esr2 |
estrogen receptor 2 (beta) |
multiple interactions decreases expression |
EXP |
bisphenol A inhibits the reaction [Streptozocin results in decreased expression of ESR2 mRNA]; bisphenol A inhibits the reaction [Streptozocin results in decreased expression of ESR2 protein]; ESR2 protein affects the reaction [Raloxifene Hydrochloride inhibits the reaction [Streptozocin results in decreased secretion of MMP2 protein]]; Ethinyl Estradiol inhibits the reaction [Streptozocin results in decreased expression of ESR2 mRNA]; octylphenol inhibits the reaction [Streptozocin results in decreased expression of ESR2 mRNA] Streptozocin results in decreased expression of ESR2 mRNA; Streptozocin results in decreased expression of ESR2 protein |
CTD |
PMID:23471663 PMID:24781736 PMID:35051763 |
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NCBI chr12:76,167,193...76,224,033
Ensembl chr12:76,167,193...76,224,033
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G |
Etfa |
electron transferring flavoprotein, alpha polypeptide |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of ETFA protein Trientine inhibits the reaction [Streptozocin results in decreased expression of ETFA protein] |
CTD |
PMID:19634143 |
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NCBI chr 9:55,361,720...55,419,528
Ensembl chr 9:55,361,792...55,419,527
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G |
Etfb |
electron transferring flavoprotein, beta polypeptide |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of ETFB protein Trientine inhibits the reaction [Streptozocin results in decreased expression of ETFB protein] |
CTD |
PMID:19634143 |
|
NCBI chr 7:43,093,496...43,107,224
Ensembl chr 7:43,093,507...43,107,224
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G |
Etfdh |
electron transferring flavoprotein, dehydrogenase |
affects expression |
EXP |
Streptozocin affects the expression of ETFDH mRNA |
CTD |
PMID:18583417 |
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NCBI chr 3:79,511,095...79,536,074
Ensembl chr 3:79,511,095...79,536,807
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G |
Ets1 |
E26 avian leukemia oncogene 1, 5' domain |
multiple interactions decreases expression |
ISO EXP |
SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of ETS1 mRNA] |
CTD |
PMID:27629361 |
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NCBI chr 9:32,547,501...32,669,116
Ensembl chr 9:32,547,517...32,669,116
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G |
Eya2 |
EYA transcriptional coactivator and phosphatase 2 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of EYA2 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of EYA2 mRNA] |
CTD |
PMID:33484791 |
|
NCBI chr 2:165,436,892...165,613,645
Ensembl chr 2:165,436,952...165,613,647
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G |
Ezh2 |
enhancer of zeste 2 polycomb repressive complex 2 subunit |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of EZH2 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of EZH2 protein |
CTD |
PMID:29127188 |
|
NCBI chr 6:47,507,208...47,613,843
Ensembl chr 6:47,507,073...47,572,275
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G |
F3 |
coagulation factor III, tissue factor |
decreases activity |
ISO |
Streptozocin results in decreased activity of F3 protein |
CTD |
PMID:32864810 |
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NCBI chr 3:121,517,186...121,528,701
Ensembl chr 3:121,517,186...121,528,697
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G |
Fabp4 |
fatty acid binding protein 4, adipocyte |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of FABP4 mRNA |
CTD |
PMID:29127188 |
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NCBI chr 3:10,269,406...10,273,653
Ensembl chr 3:10,269,148...10,273,636
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G |
Fabp7 |
fatty acid binding protein 7, brain |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of FABP7 mRNA |
CTD |
PMID:29127188 |
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NCBI chr10:57,661,019...57,664,546
Ensembl chr10:57,660,977...57,664,546
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G |
Fadd |
Fas associated via death domain |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of FADD protein Anthocyanins inhibits the reaction [Streptozocin results in increased expression of FADD protein] |
CTD |
PMID:28856781 |
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NCBI chr 7:144,132,060...144,136,178
Ensembl chr 7:144,131,055...144,136,200
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G |
Fads1 |
fatty acid desaturase 1 |
decreases expression |
ISO |
Streptozocin results in decreased expression of FADS1 mRNA |
CTD |
PMID:25246140 |
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NCBI chr19:10,160,245...10,174,238
Ensembl chr19:10,160,252...10,174,241
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G |
Fam184a |
family with sequence similarity 184, member A |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of FAM184A mRNA |
CTD |
PMID:33484791 |
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NCBI chr10:53,509,131...53,627,368
Ensembl chr10:53,509,241...53,627,219
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G |
Fars2 |
phenylalanine-tRNA synthetase 2, mitochondrial |
affects expression |
EXP |
Streptozocin affects the expression of FARS2 mRNA |
CTD |
PMID:18583417 |
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NCBI chr13:36,301,373...36,721,569
Ensembl chr13:36,301,395...36,910,254
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G |
Fas |
Fas cell surface death receptor |
multiple interactions increases expression |
ISO |
Anthocyanins inhibits the reaction [Streptozocin results in increased expression of FAS protein] |
CTD |
PMID:28856781 |
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NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
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G |
Fasl |
Fas ligand |
multiple interactions increases expression |
ISO |
Anthocyanins inhibits the reaction [Streptozocin results in increased expression of FASLG protein]; rosiglitazone inhibits the reaction [Streptozocin results in increased expression of FASLG mRNA] Streptozocin results in increased expression of FASLG mRNA; Streptozocin results in increased expression of FASLG protein |
CTD |
PMID:21791967 PMID:28856781 |
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NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064
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G |
Fasn |
fatty acid synthase |
decreases expression multiple interactions increases expression |
ISO EXP |
Streptozocin results in decreased expression of FASN mRNA Allopurinol inhibits the reaction [Streptozocin results in increased expression of FASN mRNA]; Allopurinol inhibits the reaction [Streptozocin results in increased expression of FASN protein]; GHRL protein promotes the reaction [Streptozocin results in decreased expression of FASN mRNA]; INS protein inhibits the reaction [Streptozocin results in decreased expression of FASN mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of FASN mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of FASN protein] Streptozocin results in increased expression of FASN mRNA; Streptozocin results in increased expression of FASN protein [Dietary Fats co-treated with Streptozocin] results in decreased expression of FASN mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of FASN mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of FASN mRNA; Acrylamide inhibits the reaction [Streptozocin results in increased expression of FASN mRNA]; esculetin promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of FASN mRNA]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FASN mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FASN mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of FASN mRNA] |
CTD |
PMID:20219977 PMID:23647015 PMID:27769711 PMID:29988851 PMID:33812996 PMID:34896238 PMID:39047806 More...
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NCBI chr11:120,696,784...120,715,992
Ensembl chr11:120,696,672...120,715,373
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G |
Faxc |
failed axon connections homolog |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of FAXC mRNA |
CTD |
PMID:33484791 |
|
NCBI chr 4:21,930,906...22,001,461
Ensembl chr 4:21,931,329...21,996,839
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G |
Fbp1 |
fructose bisphosphatase 1 |
increases activity multiple interactions |
ISO |
Streptozocin results in increased activity of FBP1 protein citronellol inhibits the reaction [Streptozocin results in increased activity of FBP1 protein] |
CTD |
PMID:26944432 |
|
NCBI chr13:63,012,567...63,036,112
Ensembl chr13:63,012,567...63,036,096
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G |
Fbp2 |
fructose bisphosphatase 2 |
multiple interactions |
EXP |
[1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FBP2 protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of FBP2 protein |
CTD |
PMID:25446853 |
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NCBI chr13:62,984,698...63,006,214
Ensembl chr13:62,984,691...63,006,236
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G |
Fbxo32 |
F-box protein 32 |
multiple interactions increases expression |
ISO EXP |
4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of FBXO32 protein] |
CTD |
PMID:30635400 PMID:30980806 |
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NCBI chr15:58,039,275...58,078,288
Ensembl chr15:58,039,275...58,078,328
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G |
Fcer1g |
Fc receptor, IgE, high affinity I, gamma polypeptide |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of FCER1G mRNA |
CTD |
PMID:25905778 |
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NCBI chr 1:171,057,141...171,061,918
Ensembl chr 1:171,057,141...171,061,934
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G |
Fcgr3 |
Fc receptor, IgG, low affinity III |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of FCGR3 mRNA vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of FCGR3 mRNA] |
CTD |
PMID:16684804 |
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NCBI chr 1:170,878,738...170,893,477
Ensembl chr 1:170,878,743...170,892,504
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G |
Fgf15 |
fibroblast growth factor 15 |
multiple interactions |
EXP |
[Dietary Fats co-treated with Streptozocin] results in increased expression of FGF15 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of FGF15 protein |
CTD |
PMID:29382564 |
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NCBI chr 7:144,450,269...144,454,690
Ensembl chr 7:144,450,268...144,454,690
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G |
Fgf17 |
fibroblast growth factor 17 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in increased expression of FGF17 mRNA; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in increased expression of FGF17 mRNA] |
CTD |
PMID:32303808 |
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NCBI chr14:70,873,643...70,880,064
Ensembl chr14:70,873,643...70,879,708
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G |
Fgf21 |
fibroblast growth factor 21 |
multiple interactions affects response to substance |
EXP |
[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of FGF21 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of FGF21 mRNA; FGF21 protein affects the reaction [Streptozocin results in increased expression of AIFM1]; FGF21 protein affects the reaction [Streptozocin results in increased expression of CASP12 protein modified form]; FGF21 protein affects the reaction [Streptozocin results in increased expression of DDIT3]; Glucagon analog promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of FGF21 protein] FGF21 protein affects the susceptibility to Streptozocin |
CTD |
PMID:23499715 PMID:29127188 PMID:29988851 |
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NCBI chr 7:45,263,314...45,264,914
Ensembl chr 7:45,263,310...45,264,914
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G |
Fgfr1 |
fibroblast growth factor receptor 1 |
multiple interactions decreases expression |
ISO |
rosiglitazone inhibits the reaction [Streptozocin results in decreased expression of FGFR1] |
CTD |
PMID:24136780 |
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NCBI chr 8:26,008,808...26,067,819
Ensembl chr 8:26,003,670...26,065,734
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G |
Fh1 |
fumarate hydratase 1 |
affects expression |
EXP |
Streptozocin affects the expression of FH1 mRNA |
CTD |
PMID:18583417 |
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NCBI chr 1:175,428,944...175,453,201
Ensembl chr 1:175,427,940...175,453,201
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G |
Fis1 |
fission, mitochondrial 1 |
multiple interactions |
EXP |
[Dietary Fats co-treated with Streptozocin] results in increased expression of FIS1 mRNA |
CTD |
PMID:33812996 |
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NCBI chr 5:136,982,129...136,995,088
Ensembl chr 5:136,982,129...136,995,088
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G |
Fitm2 |
fat storage-inducing transmembrane protein 2 |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in decreased expression of FITM2 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 2:163,310,623...163,314,549
Ensembl chr 2:163,308,299...163,314,549
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G |
Fkbp1b |
FK506 binding protein 1b |
multiple interactions decreases expression |
EXP ISO |
Streptozocin promotes the reaction [bisphenol A results in decreased expression of FKBP1B mRNA]; Streptozocin promotes the reaction [octylphenol results in decreased expression of FKBP1B mRNA] Triterpenes inhibits the reaction [Streptozocin results in decreased expression of FKBP1B mRNA]; Triterpenes inhibits the reaction [Streptozocin results in decreased expression of FKBP1B protein] Streptozocin results in decreased expression of FKBP1B mRNA; Streptozocin results in decreased expression of FKBP1B protein |
CTD |
PMID:19000375 PMID:29935216 |
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NCBI chr12:4,883,174...4,891,736
Ensembl chr12:4,883,174...4,891,591
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G |
Flacc1 |
flagellum associated containing coiled-coil domains 1 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of FLACC1 mRNA |
CTD |
PMID:33484791 |
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NCBI chr 1:58,696,085...58,735,167
Ensembl chr 1:58,686,062...58,735,148
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G |
Flt1 |
FMS-like tyrosine kinase 1 |
multiple interactions increases expression |
ISO EXP |
Simvastatin inhibits the reaction [Streptozocin results in increased expression of FLT1 mRNA]; Simvastatin inhibits the reaction [Streptozocin results in increased phosphorylation of and results in increased expression of FLT1 protein]; Streptozocin results in increased phosphorylation of and results in increased expression of FLT1 protein |
CTD |
PMID:20821229 PMID:26073000 |
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NCBI chr 5:147,498,414...147,663,419
Ensembl chr 5:147,498,414...147,662,821
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G |
Fmo2 |
flavin containing monooxygenase 2 |
increases expression |
ISO |
Streptozocin results in increased expression of FMO2 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 1:162,701,886...162,726,327
Ensembl chr 1:162,701,886...162,726,295
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G |
Fmo4 |
flavin containing monooxygenase 4 |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in decreased expression of FMO4 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 1:162,620,757...162,643,788
Ensembl chr 1:162,620,757...162,641,541
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G |
Fn1 |
fibronectin 1 |
increases expression multiple interactions |
ISO EXP |
Streptozocin results in increased expression of FN1; Streptozocin results in increased expression of FN1 mRNA; Streptozocin results in increased expression of FN1 protein 3-aminobenzamide inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; [Streptozocin co-treated with Cadmium] results in increased expression of FN1 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein; Aspirin inhibits the reaction [Streptozocin results in increased expression of FN1]; benazepril inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; Carvedilol inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein]; esculetin inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; esculetin inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; fasudil inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; fenugreek seed meal inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; Gallic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of FN1 protein]; Organoselenium Compounds inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; stannous mesoporphyrin inhibits the reaction [4-(4-(3-adamantan-1-ylureido)cyclohexyloxy)benzoic acid inhibits the reaction [Streptozocin results in increased expression of FN1 protein]]; Trientine inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; XLF-III-43 inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; Zinc inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA] [AM6545 co-treated with Perindopril] inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; [Dietary Fats co-treated with Streptozocin] results in increased expression of FN1 protein; [fatostatin co-treated with Streptozocin] results in increased expression of FN1 mRNA; [fatostatin co-treated with Streptozocin] results in increased expression of FN1 protein; [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of FN1 protein]; [Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of FN1 protein; AM6545 inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; AM6545 inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; CREB1 protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein]; CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FN1 protein]; HDAC3 protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein]; KLF15 gene mutant form inhibits the reaction [CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FN1 protein]]; KLF15 gene mutant form promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FN1 protein]; Perindopril inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; Perindopril inhibits the reaction [Streptozocin results in increased expression of FN1 protein] |
CTD |
PMID:11798618 PMID:12140129 PMID:14586741 PMID:16973718 PMID:19895808 PMID:21300041 PMID:21450970 PMID:21998146 PMID:22228707 PMID:22733486 PMID:23376009 PMID:23611540 PMID:24413998 PMID:24877639 PMID:25057273 PMID:25240712 PMID:25301743 PMID:26341651 PMID:27292126 PMID:29420703 PMID:30184259 PMID:31009641 PMID:34310909 PMID:38282657 More...
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NCBI chr 1:71,624,632...71,692,439
Ensembl chr 1:71,624,679...71,692,359
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G |
Fos |
FBJ osteosarcoma oncogene |
multiple interactions increases expression |
EXP |
formononetin inhibits the reaction [Streptozocin results in increased expression of FOS mRNA]; formononetin inhibits the reaction [Streptozocin results in increased expression of FOS protein] Streptozocin results in increased expression of FOS mRNA; Streptozocin results in increased expression of FOS protein |
CTD |
PMID:35315182 |
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NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
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G |
Fosb |
FBJ osteosarcoma oncogene B |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of FOSB mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of FOSB mRNA] |
CTD |
PMID:33484791 |
|
NCBI chr 7:19,036,621...19,043,970
Ensembl chr 7:19,036,621...19,043,976
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G |
Foxa2 |
forkhead box A2 |
multiple interactions |
ISO |
copper bis(3,5-diisopropylsalicylate) inhibits the reaction [Streptozocin results in decreased expression of FOXA2] |
CTD |
PMID:23795780 |
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NCBI chr 2:147,884,797...147,888,889
Ensembl chr 2:147,884,797...147,888,889
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G |
Foxo1 |
forkhead box O1 |
multiple interactions increases acetylation decreases expression decreases phosphorylation |
EXP ISO |
[Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of FOXO1 protein; resveratrol inhibits the reaction [Streptozocin results in increased acetylation of FOXO1 protein]; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of FOXO1 protein] [Dietary Fats co-treated with Streptozocin] affects the localization of FOXO1 protein; Butyric Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] affects the localization of FOXO1 protein]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] affects the localization of FOXO1 protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of FOXO1 mRNA]; Resveratrol inhibits the reaction [Streptozocin results in increased phosphorylation of and results in decreased activity of FOXO1 protein]; Streptozocin results in increased phosphorylation of and results in decreased activity of FOXO1 protein; Tribulus extract inhibits the reaction [Streptozocin results in decreased phosphorylation of FOXO1 protein] |
CTD |
PMID:22733486 PMID:24889822 PMID:26522834 PMID:27270450 PMID:36627075 |
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NCBI chr 3:52,175,758...52,257,530
Ensembl chr 3:52,175,757...52,260,642
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G |
Foxo3 |
forkhead box O3 |
decreases expression increases expression multiple interactions |
ISO EXP |
Streptozocin results in decreased expression of FOXO3 protein Streptozocin results in increased expression of FOXO3 protein modified form Streptozocin results in increased expression of FOXO3 protein; Streptozocin results in increased expression of FOXO3 protein modified form [Streptozocin co-treated with Resveratrol co-treated with Ramipril] results in increased phosphorylation of FOXO3 protein; [Streptozocin co-treated with Resveratrol] results in increased phosphorylation of FOXO3 protein; Resveratrol inhibits the reaction [Streptozocin results in increased expression of FOXO3 protein] |
CTD |
PMID:17082237 PMID:18703049 PMID:23792339 PMID:31062909 |
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NCBI chr10:42,057,841...42,152,691
Ensembl chr10:42,057,837...42,152,751
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G |
Fshb |
follicle stimulating hormone beta |
decreases expression multiple interactions |
ISO EXP |
Streptozocin results in decreased expression of FSHB protein Sildenafil Citrate inhibits the reaction [Streptozocin results in decreased expression of FSHB protein]; vitexin inhibits the reaction [Streptozocin results in decreased expression of FSHB protein] [Streptozocin co-treated with Fructose] results in decreased expression of FSHB protein; Acetates inhibits the reaction [[Streptozocin co-treated with Fructose] results in decreased expression of FSHB protein]; carvacrol affects the reaction [Streptozocin results in decreased expression of FSHB protein] |
CTD |
PMID:19931367 PMID:30365938 PMID:32153207 PMID:34656705 |
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NCBI chr 2:106,886,331...106,889,996
Ensembl chr 2:106,886,485...106,890,001
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G |
Fshr |
follicle stimulating hormone receptor |
multiple interactions decreases expression |
ISO |
carvacrol affects the reaction [Streptozocin results in decreased expression of FSHR mRNA]; carvacrol affects the reaction [Streptozocin results in decreased expression of FSHR protein] Streptozocin results in decreased expression of FSHR mRNA; Streptozocin results in decreased expression of FSHR protein |
CTD |
PMID:32153207 |
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NCBI chr17:89,292,380...89,508,103
Ensembl chr17:89,292,380...89,508,103
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G |
Fth1 |
ferritin heavy polypeptide 1 |
multiple interactions |
EXP |
[Dietary Fats co-treated with Streptozocin] results in increased expression of FTH1 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of FTH1 mRNA; omaveloxolone analog promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FTH1 mRNA]; omaveloxolone promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FTH1 mRNA] |
CTD |
PMID:32410268 PMID:38483099 |
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NCBI chr19:9,957,964...9,962,475
Ensembl chr19:9,957,962...9,962,462
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G |
Ftl1 |
ferritin light polypeptide 1 |
multiple interactions |
EXP |
[Dietary Fats co-treated with Streptozocin] results in increased expression of FTL1 protein |
CTD |
PMID:38483099 |
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NCBI chr 7:45,107,368...45,109,310
Ensembl chr 7:45,107,368...45,109,308
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G |
Fxyd2 |
FXYD domain-containing ion transport regulator 2 |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of FXYD2 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 9:45,311,007...45,321,576
Ensembl chr 9:45,310,967...45,321,576
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G |
G6pc1 |
glucose-6-phosphatase catalytic subunit 1 |
multiple interactions decreases activity increases activity increases expression decreases expression |
ISO EXP |
4-hydroxyphenylethanol inhibits the reaction [Streptozocin results in increased activity of G6PC1 protein]; bis(maltolato)oxovanadium(IV) inhibits the reaction [Streptozocin results in increased expression of G6PC1 mRNA]; citronellol inhibits the reaction [Streptozocin results in increased activity of G6PC1 protein]; Glyburide inhibits the reaction [Streptozocin results in increased activity of G6PC1 protein]; Phlorhizin inhibits the reaction [Streptozocin results in increased expression of G6PC1 mRNA]; Plant Extracts inhibits the reaction [Streptozocin results in decreased activity of G6PC1 protein]; Plant Extracts inhibits the reaction [Streptozocin results in increased expression of G6PC1 mRNA]; plumbagin inhibits the reaction [Streptozocin results in increased activity of G6PC1 protein]; Polysaccharides inhibits the reaction [Streptozocin results in decreased activity of G6PC1 protein]; Tribulus extract inhibits the reaction [Streptozocin results in increased expression of G6PC1 protein]; Trientine inhibits the reaction [Streptozocin results in increased expression of G6PC1 protein] Streptozocin results in increased expression of G6PC1 mRNA; Streptozocin results in increased expression of G6PC1 protein Streptozocin results in decreased expression of G6PC1 mRNA [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of G6PC1 protein]; [Dietary Fats co-treated with Streptozocin] results in decreased activity of G6PC1 protein; [Dietary Fats co-treated with Streptozocin] results in increased expression of G6PC1 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of G6PC1 mRNA; Acrylamide inhibits the reaction [Streptozocin results in increased expression of G6PC1 mRNA]; esculetin promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of G6PC1 protein]; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of G6PC1 mRNA] |
CTD |
PMID:12446591 PMID:19634143 PMID:22960630 PMID:25446853 PMID:25641191 PMID:25905778 PMID:26522834 PMID:26616445 PMID:26944432 PMID:27038876 PMID:27769711 PMID:34896238 PMID:36627075 More...
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NCBI chr11:101,258,542...101,268,729
Ensembl chr11:101,258,387...101,268,729
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G |
G6pc3 |
glucose 6 phosphatase, catalytic, 3 |
multiple interactions decreases activity |
ISO |
Glyburide inhibits the reaction [Streptozocin results in decreased activity of G6PC3 protein]; Hesperidin inhibits the reaction [Streptozocin results in decreased activity of G6PC3 protein] |
CTD |
PMID:31345080 |
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NCBI chr11:102,080,525...102,084,907
Ensembl chr11:102,080,446...102,084,907
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G |
G6pdx |
glucose-6-phosphate dehydrogenase X-linked |
multiple interactions decreases activity decreases expression |
ISO EXP |
2-tert-butylhydroquinone inhibits the reaction [Streptozocin results in decreased expression of G6PD mRNA]; 2-tert-butylhydroquinone inhibits the reaction [Streptozocin results in decreased expression of G6PD protein]; 4-hydroxyphenylethanol inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]; [Dietary Fats co-treated with Streptozocin] results in decreased activity of G6PD protein; [Phytic Acid co-treated with Inositol] inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]; [Streptozocin co-treated with Cadmium] results in decreased activity of G6PD protein; [Streptozocin co-treated with Niacinamide] affects the activity of G6PD protein; arjunolic acid inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]; citronellol inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]; G6PD protein promotes the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; G6PD protein promotes the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; geraniol inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]; Gliclazide inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]; Glyburide inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]; Hesperidin inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased activity of G6PD protein]; nerolidol inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of G6PD protein]; NFE2L2 protein inhibits the reaction [Streptozocin results in decreased expression of G6PD mRNA]; NFE2L2 protein inhibits the reaction [Streptozocin results in decreased expression of G6PD protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] affects the activity of G6PD protein] [Streptozocin co-treated with Dietary Fats] results in decreased activity of G6PD protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased activity of G6PD protein] Streptozocin results in decreased expression of G6PD mRNA; Streptozocin results in decreased expression of G6PD protein |
CTD |
PMID:19059388 PMID:19133311 PMID:19682444 PMID:24923654 PMID:25641191 PMID:26944432 PMID:28330423 PMID:28757134 PMID:31345080 PMID:33484791 PMID:35478295 PMID:36169646 PMID:37354076 More...
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NCBI chr X:73,453,089...73,472,486
Ensembl chr X:73,453,089...73,472,800
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G |
Gabra4 |
gamma-aminobutyric acid type A receptor subunit alpha 4 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of GABRA4 mRNA |
CTD |
PMID:33484791 |
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NCBI chr 5:71,727,077...71,815,651
Ensembl chr 5:71,727,092...71,815,651
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G |
Gabrr1 |
gamma-aminobutyric acid type A receptor subunit rho 1 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of GABRR1 mRNA; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of GABRR1 mRNA] |
CTD |
PMID:32303808 |
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NCBI chr 4:33,132,556...33,163,606
Ensembl chr 4:33,132,521...33,163,588
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G |
Gad1 |
glutamate decarboxylase 1 |
multiple interactions decreases expression |
ISO |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of GAD1 protein; Curcumin inhibits the reaction [Streptozocin results in decreased expression of GAD1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in decreased expression of GAD1 mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of GAD1 protein] |
CTD |
PMID:23267840 PMID:35085591 |
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NCBI chr 2:70,392,109...70,432,358
Ensembl chr 2:70,383,416...70,432,358
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G |
Gadd45b |
growth arrest and DNA-damage-inducible 45 beta |
multiple interactions |
ISO EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of GADD45B mRNA [Streptozocin co-treated with Dietary Fats] results in increased expression of GADD45B mRNA |
CTD |
PMID:25905778 PMID:29127188 |
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NCBI chr10:80,765,925...80,768,038
Ensembl chr10:80,765,907...80,768,038
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G |
Galt |
galactose-1-phosphate uridyl transferase |
decreases expression |
ISO |
Streptozocin results in decreased expression of GALT mRNA |
CTD |
PMID:25905778 |
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NCBI chr 4:41,755,517...41,759,243
Ensembl chr 4:41,755,228...41,758,695
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G |
Gas6 |
growth arrest specific 6 |
increases expression |
ISO |
Streptozocin results in increased expression of GAS6 protein |
CTD |
PMID:12644472 |
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NCBI chr 8:13,515,374...13,544,535
Ensembl chr 8:13,515,374...13,544,490
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G |
Gatm |
glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
multiple interactions decreases expression |
ISO |
Trientine inhibits the reaction [Streptozocin results in decreased expression of GATM protein] |
CTD |
PMID:19634143 |
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NCBI chr 2:122,424,954...122,441,758
Ensembl chr 2:122,424,948...122,441,784
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G |
Gcg |
glucagon |
multiple interactions decreases expression |
ISO |
[Dietary Fats co-treated with Streptozocin] results in increased expression of GCG protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of GCG mRNA; Butyric Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GCG protein]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GCG protein]; rosiglitazone inhibits the reaction [Streptozocin results in decreased expression of GCG mRNA]; Sitagliptin Phosphate inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GCG mRNA] |
CTD |
PMID:18998217 PMID:23466488 PMID:27270450 |
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NCBI chr 2:62,304,874...62,313,997
Ensembl chr 2:62,304,874...62,313,994
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G |
Gck |
glucokinase |
multiple interactions decreases expression |
EXP ISO |
[1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GCK protein]; [Dietary Fats co-treated with Streptozocin] results in decreased activity of GCK protein; [Dietary Fats co-treated with Streptozocin] results in decreased expression of GCK mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of GCK protein; [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of GCK protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of GCK mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of GCK protein; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GCK mRNA] [Dietary Fats co-treated with Streptozocin] results in decreased activity of GCK protein; [Dietary Fats co-treated with Streptozocin] results in decreased expression of GCK mRNA; nerolidol inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of GCK protein]; Plant Extracts inhibits the reaction [Streptozocin results in decreased expression of GCK mRNA]; repaglinide analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GCK mRNA]; repaglinide inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GCK mRNA] |
CTD |
PMID:25446853 PMID:26522834 PMID:27038876 PMID:27769711 PMID:29127188 PMID:33359794 PMID:33484791 PMID:35702883 PMID:36169646 More...
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NCBI chr11:5,850,816...5,900,081
Ensembl chr11:5,850,820...5,900,081
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G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
multiple interactions decreases expression |
ISO EXP |
[Streptozocin co-treated with Niacinamide] results in decreased expression of GCLC mRNA; [Streptozocin co-treated with Niacinamide] results in decreased expression of GCLC protein; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of GCLC mRNA]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of GCLC protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GCLC mRNA]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GCLC protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GCLC mRNA]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GCLC protein] [Dietary Fats co-treated with Streptozocin] results in decreased expression of GCLC mRNA; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GCLC mRNA] Streptozocin results in decreased expression of GCLC mRNA; Streptozocin results in decreased expression of GCLC protein |
CTD |
PMID:21439372 PMID:33359794 PMID:33639173 |
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NCBI chr 9:77,661,817...77,701,771
Ensembl chr 9:77,661,817...77,701,767
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G |
Gclm |
glutamate-cysteine ligase, modifier subunit |
multiple interactions |
EXP |
[Dietary Fats co-treated with Streptozocin] results in decreased expression of GCLM mRNA |
CTD |
PMID:33359794 |
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NCBI chr 3:122,039,206...122,060,864
Ensembl chr 3:122,039,206...122,064,381
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G |
Gcnt2 |
glucosaminyl (N-acetyl) transferase 2 (I blood group) |
increases expression |
ISO |
Streptozocin results in increased expression of GCNT2 mRNA |
CTD |
PMID:25905778 |
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NCBI chr13:41,013,417...41,114,368
Ensembl chr13:41,013,230...41,114,368
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G |
Gda |
guanine deaminase |
increases expression |
ISO |
Streptozocin results in increased expression of GDA mRNA |
CTD |
PMID:25905778 |
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NCBI chr19:21,368,671...21,450,025
Ensembl chr19:21,368,671...21,450,809
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G |
Gdnf |
glial cell line derived neurotrophic factor |
multiple interactions decreases expression |
ISO |
Vitamin B 12 inhibits the reaction [Streptozocin results in decreased expression of GDNF protein] |
CTD |
PMID:38049026 |
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NCBI chr15:7,839,529...7,867,061
Ensembl chr15:7,840,327...7,867,056
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G |
Gfap |
glial fibrillary acidic protein |
multiple interactions increases expression decreases expression |
ISO EXP |
Ibuprofen inhibits the reaction [Streptozocin results in increased expression of GFAP mRNA]; Ibuprofen inhibits the reaction [Streptozocin results in increased expression of GFAP protein]; Memantine inhibits the reaction [Streptozocin results in increased expression of GFAP mRNA]; Memantine inhibits the reaction [Streptozocin results in increased expression of GFAP protein]; Vitamin B 12 inhibits the reaction [Streptozocin results in increased expression of GFAP protein] Streptozocin results in increased expression of GFAP mRNA; Streptozocin results in increased expression of GFAP protein Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of GFAP protein]; Physostigmine inhibits the reaction [Streptozocin results in decreased expression of GFAP protein] |
CTD |
PMID:24333387 PMID:28499986 PMID:38049026 |
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NCBI chr11:102,778,162...102,791,368
Ensembl chr11:102,778,162...102,791,738
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G |
Gfm1 |
G elongation factor, mitochondrial 1 |
affects expression |
EXP |
Streptozocin affects the expression of GFM1 mRNA |
CTD |
PMID:18583417 |
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NCBI chr 3:67,337,448...67,382,401
Ensembl chr 3:67,337,429...67,383,862
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G |
Ggt1 |
gamma-glutamyltransferase 1 |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of GGT1 protein [resveratrol co-treated with Streptozocin] results in increased expression of GGT1 mRNA; Trientine inhibits the reaction [Streptozocin results in decreased expression of GGT1 protein] |
CTD |
PMID:19634143 PMID:25905778 |
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NCBI chr10:75,396,910...75,422,027
Ensembl chr10:75,397,438...75,422,034
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G |
Ghr |
growth hormone receptor |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in decreased expression of GHR mRNA |
CTD |
PMID:25905778 |
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NCBI chr15:3,347,237...3,612,834
Ensembl chr15:3,347,242...3,612,974
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G |
Ghrl |
ghrelin |
multiple interactions |
ISO |
GHRL protein promotes the reaction [Streptozocin results in decreased expression of CARTPT mRNA]; GHRL protein promotes the reaction [Streptozocin results in decreased expression of FASN mRNA]; GHRL protein promotes the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA] |
CTD |
PMID:20219977 |
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NCBI chr 6:113,693,080...113,696,872
Ensembl chr 6:113,693,080...113,696,841
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G |
Gk |
glycerol kinase |
decreases expression multiple interactions |
ISO EXP |
Streptozocin results in decreased expression of GK mRNA [Dietary Fats co-treated with Streptozocin] results in increased expression of GK mRNA; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GK mRNA] |
CTD |
PMID:25905778 PMID:33812996 |
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NCBI chr X:84,745,543...84,820,425
Ensembl chr X:84,745,543...84,820,425
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G |
Glb1 |
galactosidase, beta 1 |
multiple interactions increases expression |
EXP |
2-amino-6-boronohexanoic acid inhibits the reaction [Streptozocin results in increased expression of GLB1 protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of GLB1 protein; ARG1 gene mutant form inhibits the reaction [Streptozocin results in increased expression of GLB1 protein] |
CTD |
PMID:29673160 PMID:38483099 |
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NCBI chr 9:114,230,146...114,303,447
Ensembl chr 9:114,230,144...114,303,966
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G |
Glis1 |
GLIS family zinc finger 1 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of GLIS1 mRNA |
CTD |
PMID:33484791 |
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NCBI chr 4:107,283,840...107,492,258
Ensembl chr 4:107,291,788...107,492,258
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G |
Glo1 |
glyoxalase 1 |
multiple interactions |
ISO |
[Streptozocin co-treated with Niacinamide] results in decreased activity of GLO1 protein; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of GLO1 protein]; resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of GLO1 protein] |
CTD |
PMID:21439372 |
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NCBI chr17:30,811,835...30,831,633
Ensembl chr17:30,803,910...30,845,845
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G |
Glp1r |
glucagon-like peptide 1 receptor |
multiple interactions |
ISO |
[Fructose co-treated with Streptozocin] results in decreased expression of GLP1R mRNA; Ghrelin inhibits the reaction [[Fructose co-treated with Streptozocin] results in decreased expression of GLP1R mRNA] |
CTD |
PMID:31468622 |
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NCBI chr17:31,120,841...31,155,484
Ensembl chr17:31,120,791...31,159,765
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G |
Glud1 |
glutamate dehydrogenase 1 |
multiple interactions |
ISO |
[Dietary Fats co-treated with Streptozocin] results in decreased expression of GLUD1 mRNA; repaglinide analog affects the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GLUD1 mRNA]; repaglinide inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GLUD1 mRNA] |
CTD |
PMID:35702883 |
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NCBI chr14:34,032,684...34,066,990
Ensembl chr14:34,032,684...34,067,222
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G |
Glul |
glutamate-ammonia ligase |
multiple interactions decreases expression |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of GLUL mRNA; resveratrol inhibits the reaction [Streptozocin results in decreased expression of GLUL mRNA]; resveratrol inhibits the reaction [Streptozocin results in decreased expression of GLUL protein] Streptozocin results in decreased expression of GLUL mRNA; Streptozocin results in decreased expression of GLUL protein |
CTD |
PMID:25905778 PMID:26677078 |
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NCBI chr 1:153,775,692...153,785,469
Ensembl chr 1:153,775,690...153,785,469
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G |
Gna11 |
guanine nucleotide binding protein, alpha 11 |
multiple interactions increases expression |
ISO |
acetovanillone inhibits the reaction [Streptozocin results in increased expression of GNA11 protein]; CAT protein inhibits the reaction [Streptozocin results in increased expression of GNA11 protein] |
CTD |
PMID:20691780 |
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NCBI chr10:81,364,558...81,380,996
Ensembl chr10:81,364,558...81,381,024
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G |
Gnai2 |
G protein subunit alpha i2 |
multiple interactions decreases expression |
ISO |
Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of GNAI2 protein]; diphenyleneiodonium inhibits the reaction [Streptozocin results in decreased expression of GNAI2 protein] |
CTD |
PMID:18441196 |
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NCBI chr 9:107,491,324...107,512,542
Ensembl chr 9:107,491,324...107,512,566
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G |
Gnai3 |
G protein subunit alpha i3 |
multiple interactions decreases expression |
ISO |
Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of GNAI3 protein]; diphenyleneiodonium inhibits the reaction [Streptozocin results in decreased expression of GNAI3 protein] |
CTD |
PMID:18441196 |
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NCBI chr 3:108,014,591...108,053,468
Ensembl chr 3:108,014,596...108,053,462
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G |
Gnaq |
guanine nucleotide binding protein, alpha q polypeptide |
multiple interactions increases expression |
ISO |
acetovanillone inhibits the reaction [Streptozocin results in increased expression of GNAQ protein]; CAT protein inhibits the reaction [Streptozocin results in increased expression of GNAQ protein] |
CTD |
PMID:20691780 |
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NCBI chr19:16,110,048...16,365,884
Ensembl chr19:16,110,195...16,364,827
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G |
Gngt1 |
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of GNGT1 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of GNGT1 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 6:3,989,082...3,997,441
Ensembl chr 6:3,993,792...3,997,436
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G |
Gnmt |
glycine N-methyltransferase |
multiple interactions increases activity increases expression |
ISO |
Folic Acid inhibits the reaction [Streptozocin results in increased activity of GNMT protein] Streptozocin results in increased expression of GNMT mRNA; Streptozocin results in increased expression of GNMT protein |
CTD |
PMID:16835399 |
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NCBI chr17:47,036,590...47,040,091
Ensembl chr17:47,036,590...47,040,094
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G |
Got1 |
glutamic-oxaloacetic transaminase 1, soluble |
multiple interactions increases secretion |
ISO EXP |
[Resveratrol co-treated with Streptozocin] results in decreased expression of GOT1 mRNA; Atorvastatin inhibits the reaction [Streptozocin results in increased secretion of GOT1 protein] [Streptozocin co-treated with Dietary Fats] results in increased expression of GOT1 protein; [Streptozocin co-treated with Dietary Fats] results in increased secretion of GOT1 protein; aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased secretion of GOT1 protein]; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of GOT1 protein] |
CTD |
PMID:25905778 PMID:30657622 PMID:35961541 PMID:37482253 |
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NCBI chr19:43,488,191...43,514,743
Ensembl chr19:43,488,191...43,513,044
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G |
Got2 |
glutamatic-oxaloacetic transaminase 2, mitochondrial |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of GOT2 protein Trientine inhibits the reaction [Streptozocin results in increased expression of GOT2 protein] |
CTD |
PMID:19634143 |
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NCBI chr 8:96,590,761...96,615,029
Ensembl chr 8:96,590,762...96,615,175
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G |
Gpc1 |
glypican 1 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of GPC1 mRNA |
CTD |
PMID:29127188 |
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NCBI chr 1:92,759,367...92,787,933
Ensembl chr 1:92,759,367...92,788,501
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G |
Gpd1 |
glycerol-3-phosphate dehydrogenase 1 (soluble) |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in decreased expression of GPD1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr15:99,615,468...99,622,895
Ensembl chr15:99,615,396...99,622,886
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G |
Gprc6a |
G protein-coupled receptor, family C, group 6, member A |
multiple interactions |
ISO |
[Dietary Fats co-treated with Streptozocin] results in decreased expression of GPRC6A mRNA; Warfarin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GPRC6A mRNA] |
CTD |
PMID:27488359 |
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NCBI chr10:51,490,919...51,507,554
Ensembl chr10:51,490,919...51,507,557
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G |
Gpt |
glutamic pyruvic transaminase, soluble |
multiple interactions increases expression increases activity increases secretion |
ISO EXP |
4-hydroxyisoleucine inhibits the reaction [Streptozocin results in increased expression of GPT protein]; [Dietary Fats co-treated with Streptozocin] results in increased activity of GPT protein; [Dietary Fats co-treated with Streptozocin] results in increased expression of GPT protein; [Streptozocin co-treated with Dietary Fats] results in increased activity of GPT protein; [Zinc co-treated with Selenium] inhibits the reaction [Streptozocin results in increased expression of GPT protein]; allyl isothiocyanate inhibits the reaction [Streptozocin promotes the reaction [Dietary Fats results in increased expression of GPT protein]]; Atorvastatin inhibits the reaction [Streptozocin results in increased secretion of GPT protein]; dapagliflozin inhibits the reaction [Streptozocin results in increased expression of GPT protein]; Ellagic Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GPT protein]; Eugenol inhibits the reaction [Streptozocin results in increased expression of GPT protein]; Ficusin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased activity of GPT protein]; Fungal Polysaccharides inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased activity of GPT protein]; Glyburide inhibits the reaction [Streptozocin results in increased activity of GPT protein]; mangiferin inhibits the reaction [Streptozocin results in increased activity of GPT protein]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased activity of GPT protein]; morin analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased activity of GPT protein]; naringenin inhibits the reaction [Streptozocin results in increased activity of GPT protein]; nerolidol inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased activity of GPT protein]; Pioglitazone inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased activity of GPT protein]; Plant Extracts inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased activity of GPT protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of GPT protein]; sodium tungstate(VI) inhibits the reaction [Streptozocin results in increased activity of GPT protein]; Streptozocin promotes the reaction [Dietary Fats results in increased expression of GPT protein]; Tribulus extract inhibits the reaction [Streptozocin results in increased activity of GPT protein]; Zinc Compounds inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased activity of GPT protein] [Acrylamide co-treated with Streptozocin] results in increased activity of GPT protein; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of GPT protein; [omaveloxolone analog co-treated with Streptozocin co-treated with Dietary Fats] results in increased expression of GPT protein; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of GPT protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of GPT protein; [Streptozocin co-treated with Dietary Fats] results in increased secretion of GPT protein; aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased secretion of GPT protein]; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of GPT protein]; Metformin inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of GPT protein]; perilla seed oil inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of GPT protein]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of GPT protein] |
CTD |
PMID:11357483 PMID:24854284 PMID:24877639 PMID:26071184 PMID:27350165 PMID:29223569 PMID:29614383 PMID:30144451 PMID:30657622 PMID:30927557 PMID:31100278 PMID:31743741 PMID:32233808 PMID:32410268 PMID:32812462 PMID:33524429 PMID:34896238 PMID:35072544 PMID:35961541 PMID:36169646 PMID:36627075 PMID:37054934 PMID:37352119 PMID:37482253 PMID:38047382 PMID:39047806 More...
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NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886
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G |
Gpx1 |
glutathione peroxidase 1 |
multiple interactions decreases activity decreases expression increases expression |
EXP ISO |
[Dietary Fats co-treated with Streptozocin] results in decreased expression of GPX1 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of GPX1 protein; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of GPX1 protein]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GPX1 mRNA]; Sodium Selenite inhibits the reaction [Streptozocin results in decreased activity of GPX1 protein]; Sodium Selenite inhibits the reaction [Streptozocin results in decreased expression of GPX1 mRNA] Streptozocin results in increased expression of GPX1 protein [[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in decreased expression of GPX1 mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of GPX1 mRNA; [Carbamazepine affects the susceptibility to [Dietary Fats co-treated with Streptozocin]] which results in decreased expression of GPX1 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of GPX1 mRNA; allyl methyl sulfide inhibits the reaction [Streptozocin results in decreased activity of GPX1 protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of GPX1 mRNA]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of GPX1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in decreased expression of GPX1 mRNA]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of GPX1 mRNA]; Trientine inhibits the reaction [Streptozocin results in increased expression of GPX1 protein] |
CTD |
PMID:18789669 PMID:19634143 PMID:23267840 PMID:24740756 PMID:30318971 PMID:33359794 PMID:33639173 PMID:35786680 PMID:37482253 More...
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NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542
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G |
Gpx2 |
glutathione peroxidase 2 |
multiple interactions |
ISO |
[[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in increased expression of GPX2 mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in increased expression of GPX2 mRNA; [Carbamazepine affects the susceptibility to [Dietary Fats co-treated with Streptozocin]] which results in increased expression of GPX2 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in increased expression of GPX2 mRNA; [Resveratrol co-treated with Streptozocin] results in increased expression of GPX2 mRNA |
CTD |
PMID:25905778 PMID:35786680 |
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NCBI chr12:76,839,109...76,842,328
Ensembl chr12:76,839,107...76,842,273
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G |
Gpx3 |
glutathione peroxidase 3 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of GPX3 protein Trientine inhibits the reaction [Streptozocin results in increased expression of GPX3 protein] |
CTD |
PMID:19634143 |
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NCBI chr11:54,793,680...54,801,213
Ensembl chr11:54,793,279...54,801,203
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G |
Gpx4 |
glutathione peroxidase 4 |
multiple interactions decreases expression |
EXP ISO |
[Dietary Fats co-treated with Streptozocin] results in decreased expression of GPX4 mRNA; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GPX4 mRNA] Streptozocin results in decreased expression of GPX4 protein [Zinc co-treated with Selenium] inhibits the reaction [Streptozocin results in decreased expression of GPX4 protein] |
CTD |
PMID:32233808 PMID:33359794 |
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NCBI chr10:79,883,000...79,892,273
Ensembl chr10:79,883,000...79,892,273
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G |
Gpx5 |
glutathione peroxidase 5 |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of GPX5 protein [Zinc co-treated with Selenium] inhibits the reaction [Streptozocin results in decreased expression of GPX5 protein] |
CTD |
PMID:32233808 |
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NCBI chr13:21,470,599...21,476,897
Ensembl chr13:21,470,599...21,476,901
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G |
Gramd2a |
GRAM domain containing 2A |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of GRAMD2A mRNA |
CTD |
PMID:33484791 |
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NCBI chr 9:59,587,116...59,626,156
Ensembl chr 9:59,587,427...59,626,157
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G |
Grem1 |
gremlin 1, DAN family BMP antagonist |
increases expression |
ISO |
Streptozocin results in increased expression of GREM1 mRNA |
CTD |
PMID:10744662 |
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NCBI chr 2:113,579,020...113,588,993
Ensembl chr 2:113,576,509...113,588,991
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G |
Gria4 |
glutamate receptor, ionotropic, AMPA4 (alpha 4) |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Streptozocin results in increased expression of GRIA4 protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of GRIA4 protein] |
CTD |
PMID:23267840 |
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NCBI chr 9:4,417,893...4,796,250
Ensembl chr 9:4,417,896...4,796,234
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G |
Grin1 |
glutamate receptor, ionotropic, NMDA1 (zeta 1) |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Streptozocin results in increased expression of GRIN1 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of GRIN1 protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of GRIN1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of GRIN1 protein] Streptozocin results in increased expression of GRIN1 mRNA; Streptozocin results in increased expression of GRIN1 protein |
CTD |
PMID:23267840 |
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NCBI chr 2:25,181,189...25,209,199
Ensembl chr 2:25,181,193...25,209,199
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G |
Grk2 |
G protein-coupled receptor kinase 2 |
increases localization multiple interactions |
ISO |
Streptozocin results in increased localization of GRK2 protein tempol inhibits the reaction [Streptozocin results in increased localization of GRK2 protein] |
CTD |
PMID:16478977 |
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NCBI chr19:4,336,029...4,356,356
Ensembl chr19:4,336,029...4,356,250
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G |
Grm5 |
glutamate receptor, metabotropic 5 |
increases expression |
ISO |
Streptozocin results in increased expression of GRM5 protein |
CTD |
PMID:19840219 |
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NCBI chr 7:87,233,212...87,784,271
Ensembl chr 7:87,233,376...87,784,115
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G |
Gsdmd |
gasdermin D |
multiple interactions increases expression affects response to substance |
EXP ISO |
[Dietary Fats co-treated with Streptozocin] results in increased expression of GSDMD mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of GSDMD protein; GSDMD protein affects the reaction [Streptozocin results in increased cleavage of CASP1 protein]; GSDMD protein affects the reaction [Streptozocin results in increased expression of IL18 protein]; GSDMD protein affects the reaction [Streptozocin results in increased expression of IL1B protein]; Hirudins inhibits the reaction [Streptozocin results in increased expression of and results in increased cleavage of GSDMD protein]; Hirudins inhibits the reaction [Streptozocin results in increased expression of GSDMD mRNA]; loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GSDMD mRNA]; loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GSDMD protein]; Streptozocin results in increased expression of and results in increased cleavage of GSDMD protein GSDMD protein affects the susceptibility to Streptozocin Streptozocin results in increased expression of GSDMD protein scutellarin inhibits the reaction [Streptozocin results in increased expression of GSDMD protein] |
CTD |
PMID:34212273 PMID:37081038 PMID:37473909 |
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NCBI chr15:75,733,990...75,739,257
Ensembl chr15:75,734,176...75,739,257
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G |
Gsk3b |
glycogen synthase kinase 3 beta |
decreases phosphorylation multiple interactions increases expression |
ISO EXP |
Streptozocin results in decreased phosphorylation of GSK3B protein [Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in decreased phosphorylation of GSK3B protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of GSK3B protein; Curcumin inhibits the reaction [Streptozocin results in decreased phosphorylation of GSK3B protein]; hesperetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of GSK3B protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in decreased phosphorylation of GSK3B protein]; Phosphocreatine inhibits the reaction [Streptozocin results in decreased phosphorylation of GSK3B protein]; Plant Extracts inhibits the reaction [[Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in decreased phosphorylation of GSK3B protein]; Plant Extracts inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of GSK3B protein]; Plant Extracts inhibits the reaction [Streptozocin results in increased expression of GSK3B mRNA]; Quercetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of GSK3B protein]; Streptozocin results in decreased expression of and results in decreased phosphorylation of GSK3B protein; STUB1 inhibits the reaction [Streptozocin results in decreased expression of and results in decreased phosphorylation of GSK3B protein]; Tribulus extract inhibits the reaction [Streptozocin results in decreased phosphorylation of GSK3B protein] 5-Methoxypsoralen inhibits the reaction [Streptozocin results in decreased phosphorylation of GSK3B protein]; [Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of GSK3B protein; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the phosphorylation of GSK3B protein; [Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of GSK3B protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of GSK3B protein]; Metformin inhibits the reaction [Streptozocin results in decreased phosphorylation of GSK3B protein]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of GSK3B protein]; phillyrin inhibits the reaction [Streptozocin results in decreased phosphorylation of GSK3B protein]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the phosphorylation of GSK3B protein]; Tadalafil inhibits the reaction [Streptozocin results in decreased phosphorylation of GSK3B protein] |
CTD |
PMID:25541178 PMID:27038876 PMID:28422052 PMID:31877369 PMID:33484791 PMID:33812996 PMID:34428446 PMID:34455488 PMID:34649470 PMID:34922902 PMID:35442559 PMID:36627075 PMID:39047806 More...
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NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446
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G |
Gspt2 |
G1 to S phase transition 2 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of GSPT2 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of GSPT2 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr X:93,679,675...93,682,168
Ensembl chr X:93,679,675...93,686,850
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G |
Gsr |
glutathione reductase |
multiple interactions decreases activity increases activity affects activity decreases expression |
ISO |
[Carmustine results in decreased activity of GSR protein] which results in increased susceptibility to Streptozocin; [Dietary Fats co-treated with Streptozocin] results in decreased activity of GSR protein; [Niacinamide co-treated with Streptozocin] results in decreased activity of GSR protein; [Streptozocin co-treated with Dietary Fats] results in decreased activity of GSR protein; [Streptozocin co-treated with Niacinamide] results in decreased activity of GSR protein; [Zinc Sulfate results in increased abundance of Zinc] inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; Acetylcysteine inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; arjunolic acid inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; Bezafibrate inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; caryophyllene inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; Chromium inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; chromium tripicolinate inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; Ellagic Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of GSR protein]; Gallic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased activity of GSR protein]; geraniol inhibits the reaction [Streptozocin affects the activity of GSR protein]; Gliclazide inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in decreased activity of GSR protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of GSR protein]; Glyburide inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of GSR protein]; INS protein promotes the reaction [Streptozocin results in increased activity of GSR protein]; Metformin inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; morin inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; piperlongumine inhibits the reaction [Streptozocin results in decreased expression of GSR protein]; Resveratrol inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in decreased activity of GSR protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of GSR protein]; Rosiglitazone inhibits the reaction [Streptozocin promotes the reaction [Dietary Fats results in decreased activity of GSR protein]]; Sodium Selenite inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; Streptozocin promotes the reaction [Dietary Fats results in decreased activity of GSR protein]; Zinc inhibits the reaction [Streptozocin results in decreased activity of GSR protein] |
CTD |
PMID:11424224 PMID:15720826 PMID:17145126 PMID:19682444 PMID:19840221 PMID:20053369 PMID:20307516 PMID:20620209 PMID:21439372 PMID:22476978 PMID:22940631 PMID:23122718 PMID:24752916 PMID:24877639 PMID:26341651 PMID:26748309 PMID:29441829 PMID:30817903 PMID:31009641 PMID:32812462 PMID:32864810 PMID:33724628 PMID:34039237 PMID:35414346 PMID:37354076 More...
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NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191
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G |
Gsta1 |
glutathione S-transferase, alpha 1 (Ya) |
multiple interactions increases expression |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of GSTA5 mRNA Streptozocin results in increased expression of GSTA5 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 9:78,137,951...78,149,965
Ensembl chr 9:78,137,938...78,149,966
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G |
Gsta2 |
glutathione S-transferase, alpha 2 (Yc2) |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of GSTA2 protein Trientine inhibits the reaction [Streptozocin results in increased expression of GSTA2 protein] |
CTD |
PMID:19634143 |
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NCBI chr 9:78,238,300...78,254,474
Ensembl chr 9:78,238,300...78,263,070
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G |
Gsta4 |
glutathione S-transferase, alpha 4 |
increases expression |
ISO |
Streptozocin results in increased expression of GSTA4 protein |
CTD |
PMID:14693714 |
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NCBI chr 9:78,099,248...78,116,631
Ensembl chr 9:78,090,056...78,116,631
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G |
Gstm2 |
glutathione S-transferase, mu 2 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of GSTM2 mRNA vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of GSTM2 mRNA] |
CTD |
PMID:16684804 |
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NCBI chr 3:107,889,018...107,893,736
Ensembl chr 3:107,889,018...107,893,769
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G |
Gstm5 |
glutathione S-transferase, mu 5 |
multiple interactions |
ISO |
[Streptozocin co-treated with Niacinamide] results in decreased expression of GSTM3 mRNA; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GSTM3 mRNA]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GSTM3 mRNA] |
CTD |
PMID:21439372 |
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NCBI chr 3:107,803,240...107,806,002
Ensembl chr 3:107,803,137...107,806,002
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G |
Gstp1 |
glutathione S-transferase, pi 1 |
decreases expression |
ISO |
Streptozocin results in decreased expression of GSTP1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985
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G |
Gucy1b2 |
guanylate cyclase 1, soluble, beta 2 |
decreases expression |
ISO |
Streptozocin results in decreased expression of GUCY1B2 mRNA |
CTD |
PMID:25905778 |
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NCBI chr14:62,610,384...62,693,745
Ensembl chr14:62,630,125...62,693,738
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G |
Gys1 |
glycogen synthase 1, muscle |
decreases expression multiple interactions increases phosphorylation |
ISO |
Streptozocin results in decreased expression of GYS1 mRNA Plant Extracts inhibits the reaction [Streptozocin results in decreased expression of GYS1 mRNA]; Tribulus extract inhibits the reaction [Streptozocin results in increased phosphorylation of GYS1 protein] |
CTD |
PMID:27038876 PMID:36627075 |
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NCBI chr 7:45,084,263...45,106,041
Ensembl chr 7:45,084,268...45,106,043
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G |
Gys2 |
glycogen synthase 2 |
multiple interactions |
ISO |
[Streptozocin co-treated with Niacinamide] affects the activity of GYS2 protein; resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] affects the activity of GYS2 protein] |
CTD |
PMID:19059388 |
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NCBI chr 6:142,368,339...142,418,856
Ensembl chr 6:142,368,339...142,418,835
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G |
H19 |
H19, imprinted maternally expressed transcript |
multiple interactions |
ISO |
[Resveratrol co-treated with Streptozocin] results in increased expression of H19 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 7:142,129,267...142,131,883
Ensembl chr 7:142,129,262...142,133,957
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G |
H2-DMa |
histocompatibility 2, class II, locus DMa |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of RT1-DMA mRNA |
CTD |
PMID:25905778 |
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NCBI chr17:34,338,667...34,358,075
Ensembl chr17:34,338,515...34,358,075
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G |
H2-DMb1 |
histocompatibility 2, class II, locus Mb1 |
multiple interactions |
ISO |
[Resveratrol co-treated with Streptozocin] results in increased expression of RT1-DMB mRNA |
CTD |
PMID:25905778 |
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NCBI chr17:34,372,165...34,379,203
Ensembl chr17:34,372,046...34,379,204
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G |
H2bc15 |
H2B clustered histone 15 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of H2BC14 mRNA |
CTD |
PMID:33484791 |
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NCBI chr13:21,938,246...21,938,723
Ensembl chr13:21,938,293...21,938,673
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G |
H2bc3 |
H2B clustered histone 3 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of H2BC3 mRNA |
CTD |
PMID:33484791 |
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NCBI chr13:23,930,717...23,931,206
Ensembl chr13:23,930,717...23,931,224
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G |
H3c2 |
H3 clustered histone 2 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of H3C2 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of H3C2 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr13:23,936,328...23,936,823
Ensembl chr13:23,936,250...23,936,869
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G |
Hamp |
hepcidin antimicrobial peptide |
multiple interactions |
ISO |
[Streptozocin co-treated with iron pentacarbonyl] results in increased expression of HAMP mRNA |
CTD |
PMID:22170771 |
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NCBI chr 7:30,641,793...30,643,454
Ensembl chr 7:30,641,793...30,643,457
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G |
Hao2 |
hydroxyacid oxidase 2 |
multiple interactions decreases expression |
ISO |
[resveratrol co-treated with Streptozocin] results in decreased expression of HAO2 mRNA; Trientine inhibits the reaction [Streptozocin results in decreased expression of HAO2 protein] Streptozocin results in decreased expression of HAO2 mRNA; Streptozocin results in decreased expression of HAO2 protein |
CTD |
PMID:19634143 PMID:25905778 |
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NCBI chr 3:98,781,835...98,802,692
Ensembl chr 3:98,781,837...98,800,555
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G |
Hapln1 |
hyaluronan and proteoglycan link protein 1 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of HAPLN1 mRNA |
CTD |
PMID:33484791 |
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NCBI chr13:89,688,654...89,759,951
Ensembl chr13:89,687,915...89,759,771
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G |
Havcr1 |
hepatitis A virus cellular receptor 1 |
decreases expression multiple interactions increases expression |
EXP ISO |
Streptozocin results in decreased expression of HAVCR1 mRNA [Streptozocin co-treated with Fructose] results in increased expression of HAVCR1 protein; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of HAVCR1 protein]; dapagliflozin promotes the reaction [Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of HAVCR1 protein]]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of HAVCR1 protein]; Metformin promotes the reaction [dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of HAVCR1 protein]]; sulbutiamine inhibits the reaction [Streptozocin results in increased expression of HAVCR1 protein] |
CTD |
PMID:19516248 PMID:30551545 PMID:37224990 |
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NCBI chr11:46,630,644...46,670,405
Ensembl chr11:46,625,907...46,670,405
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G |
Hba-a2 |
hemoglobin alpha, adult chain 2 |
multiple interactions increases glycation |
ISO |
[Streptozocin co-treated with Niacinamide] results in increased glycosylation of HBA1 protein; coumarin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased glycosylation of HBA1 protein] Streptozocin results in increased glycation of HBA1 protein |
CTD |
PMID:19647726 PMID:21139377 |
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NCBI chr11:32,246,492...32,247,310
Ensembl chr11:32,246,489...32,247,298
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G |
Hbb-b1 |
hemoglobin, beta adult major chain |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of HBB-B1 protein Trientine inhibits the reaction [Streptozocin results in decreased expression of HBB-B1 protein] |
CTD |
PMID:19634143 |
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G |
Hck |
hemopoietic cell kinase |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of HCK mRNA |
CTD |
PMID:25905778 |
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NCBI chr 2:152,950,388...152,993,361
Ensembl chr 2:152,950,388...152,993,361
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G |
Hdac3 |
histone deacetylase 3 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of HDAC3 protein; HDAC3 protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of MIR10A mRNA]; HDAC3 protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CREB1 protein]; HDAC3 protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein] |
CTD |
PMID:27292126 |
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NCBI chr18:38,070,024...38,088,073
Ensembl chr18:38,068,897...38,088,069
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G |
Hdac5 |
histone deacetylase 5 |
multiple interactions |
ISO |
[Streptozocin co-treated with Fructose] results in increased expression of HDAC5 protein; Acetates inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of HDAC5 protein] |
CTD |
PMID:34656705 |
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NCBI chr11:102,085,244...102,120,968
Ensembl chr11:102,085,258...102,120,992
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G |
Hesx1 |
homeobox gene expressed in ES cells |
multiple interactions |
EXP |
[Diethylhexyl Phthalate co-treated with Streptozocin co-treated with Dietary Fats] results in decreased expression of HESX1 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of HESX1 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of HESX1 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr14:26,716,322...26,724,286
Ensembl chr14:26,716,373...26,724,286
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G |
Hif1a |
hypoxia inducible factor 1, alpha subunit |
increases expression multiple interactions |
EXP ISO |
Streptozocin results in increased expression of HIF1A protein [Streptozocin co-treated with Dietary Fats] results in increased expression of HIF1A protein; bicalutamide promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of HIF1A protein]; Insulin promotes the reaction [Ozone inhibits the reaction [Streptozocin results in increased expression of HIF1A mRNA]]; Ozone inhibits the reaction [Streptozocin results in increased expression of HIF1A mRNA] |
CTD |
PMID:26073000 PMID:26614261 PMID:35151640 |
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NCBI chr12:73,948,186...73,994,304
Ensembl chr12:73,948,149...73,994,304
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G |
Hk1 |
hexokinase 1 |
decreases activity multiple interactions |
ISO |
Streptozocin results in decreased activity of HK1 protein [homocastasterone analog co-treated with Streptozocin] results in increased expression of HK1 mRNA; plumbagin inhibits the reaction [Streptozocin results in decreased activity of HK1 protein] |
CTD |
PMID:22960630 PMID:28822685 |
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NCBI chr10:62,104,634...62,215,699
Ensembl chr10:62,104,634...62,215,687
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G |
Hmgb1 |
high mobility group box 1 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of HMGB1 mRNA manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Streptozocin results in increased expression of HMGB1 mRNA] |
CTD |
PMID:19833897 |
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NCBI chr 5:148,983,512...148,989,867
Ensembl chr 5:148,983,512...149,121,299
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G |
Hmgcr |
3-hydroxy-3-methylglutaryl-Coenzyme A reductase |
multiple interactions increases expression |
ISO EXP |
[Dietary Fats co-treated with Streptozocin] results in increased expression of HMGCR mRNA; [Streptozocin co-treated with Cadmium] results in increased activity of HMGCR protein; [Streptozocin co-treated with Niacinamide] results in increased activity of HMGCR protein; [tetrahydrocurcumin co-treated with Chlorogenic Acid] results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in increased activity of HMGCR protein]; Chlorogenic Acid results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in increased activity of HMGCR protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased activity of HMGCR protein]; tetrahydrocurcumin results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in increased activity of HMGCR protein]; Warfarin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of HMGCR mRNA] Streptozocin results in increased expression of HMGCR mRNA Acrylamide inhibits the reaction [Streptozocin results in increased expression of HMGCR mRNA] |
CTD |
PMID:20696151 PMID:25240712 PMID:25905778 PMID:27488359 PMID:34896238 |
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NCBI chr13:96,785,470...96,807,444
Ensembl chr13:96,785,475...96,807,444
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G |
Hmgcs2 |
3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of HMGCS2 mRNA vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of HMGCS2 mRNA] |
CTD |
PMID:16684804 |
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NCBI chr 3:98,187,747...98,218,054
Ensembl chr 3:98,187,751...98,218,054
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G |
Hmox1 |
heme oxygenase 1 |
decreases activity multiple interactions increases expression decreases expression |
ISO EXP |
Streptozocin results in decreased activity of HMOX1 protein [cobaltiprotoporphyrin co-treated with Streptozocin] results in increased activity of HMOX1 protein; [cobaltiprotoporphyrin co-treated with Streptozocin] results in increased expression of HMOX1 protein; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of HMOX1 mRNA; [Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of HMOX1 protein]; [Streptozocin co-treated with Dietary Fats] results in decreased expression of HMOX1 protein; [Streptozocin co-treated with Hemin] results in increased activity of HMOX1 protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of HMOX1 protein; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of HMOX1 mRNA]; caffeic acid phenethyl ester inhibits the reaction [Streptozocin results in increased expression of HMOX1 protein]; chromium mesoporphyrin inhibits the reaction [[Streptozocin co-treated with Hemin] results in increased activity of HMOX1 protein]; cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of and results in decreased activity of HMOX1 protein]; cobaltiprotoporphyrin promotes the reaction [Streptozocin results in increased expression of HMOX1 protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein]; diallyl trisulfide inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein]; Dimethyl Fumarate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of HMOX1 protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of HMOX1 mRNA]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of HMOX1 protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of HMOX1 mRNA]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of HMOX1 protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of HMOX1 mRNA]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of HMOX1 mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of HMOX1 protein]; Metformin inhibits the reaction [Streptozocin results in decreased expression of HMOX1 mRNA]; Metformin inhibits the reaction [Streptozocin results in increased expression of HMOX1 mRNA]; palbinone inhibits the reaction [Streptozocin results in decreased expression of HMOX1 mRNA]; Propofol inhibits the reaction [Streptozocin results in decreased activity of HMOX1 protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of HMOX1 protein]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of HMOX1 mRNA]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein]; Streptozocin results in decreased expression of and results in decreased activity of HMOX1 protein; Streptozocin results in increased expression of and results in decreased activity of HMOX1 protein; STUB1 inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of HMOX1 mRNA]; tin mesoporphyrin inhibits the reaction [[cobaltiprotoporphyrin co-treated with Streptozocin] results in increased activity of HMOX1 protein]; tin mesoporphyrin inhibits the reaction [[cobaltiprotoporphyrin co-treated with Streptozocin] results in increased expression of HMOX1 protein] Streptozocin results in increased expression of HMOX1 mRNA; Streptozocin results in increased expression of HMOX1 protein HMOX1 protein inhibits the reaction [Streptozocin results in decreased expression of SLC25A19 protein] [Dietary Fats co-treated with Streptozocin] results in decreased expression of HMOX1 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of HMOX1 mRNA; [Streptozocin co-treated with sulforaphane] results in increased expression of HMOX1; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of HMOX1 mRNA]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of HMOX1 mRNA]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of HMOX1 mRNA]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein] Streptozocin results in decreased expression of HMOX1 mRNA; Streptozocin results in decreased expression of HMOX1 protein |
CTD |
PMID:16309587 PMID:16595661 PMID:19019021 PMID:19190261 PMID:21439372 PMID:21457706 PMID:22023613 PMID:22531820 PMID:22675305 PMID:23453443 PMID:24508943 PMID:24810525 PMID:24967692 PMID:25541178 PMID:30817903 PMID:31173751 PMID:32202043 PMID:32662907 PMID:33359794 PMID:33639173 PMID:34610774 PMID:35442559 PMID:36510688 PMID:36999408 More...
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NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
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G |
Hmox2 |
heme oxygenase 2 |
multiple interactions increases response to substance |
EXP |
cobaltiprotoporphyrin inhibits the reaction [HMOX2 gene mutant form results in increased susceptibility to Streptozocin]; tin mesoporphyrin promotes the reaction [HMOX2 gene mutant form results in increased susceptibility to Streptozocin] |
CTD |
PMID:16524951 |
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NCBI chr16:4,544,225...4,584,606
Ensembl chr16:4,544,225...4,584,606
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G |
Hnf4a |
hepatic nuclear factor 4, alpha |
multiple interactions increases expression |
EXP |
Acrylamide inhibits the reaction [Streptozocin results in increased expression of HNF4A mRNA] |
CTD |
PMID:34896238 |
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NCBI chr 2:163,348,731...163,414,827
Ensembl chr 2:163,348,728...163,414,830
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G |
Hopx |
HOP homeobox |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of HOPX mRNA |
CTD |
PMID:25905778 |
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NCBI chr 5:77,234,831...77,262,970
Ensembl chr 5:77,234,835...77,262,968
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G |
Hp |
haptoglobin |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of HP mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of HP mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 8:110,301,760...110,305,804
Ensembl chr 8:110,301,760...110,305,804
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G |
Hras |
Harvey rat sarcoma virus oncogene |
decreases farnesylation |
ISO |
Streptozocin results in decreased farnesylation of HRAS protein |
CTD |
PMID:19002579 |
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NCBI chr 7:140,770,839...140,773,938
Ensembl chr 7:140,769,018...140,773,918
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G |
Hsd17b10 |
hydroxysteroid (17-beta) dehydrogenase 10 |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of HSD17B10 protein Trientine inhibits the reaction [Streptozocin results in decreased expression of HSD17B10 protein] |
CTD |
PMID:21136691 |
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NCBI chr X:150,784,892...150,787,438
Ensembl chr X:150,784,841...150,787,438
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G |
Hsd17b2 |
hydroxysteroid (17-beta) dehydrogenase 2 |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in decreased expression of HSD17B2 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 8:118,427,752...118,485,767
Ensembl chr 8:118,428,643...118,485,766
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G |
Hsd17b4 |
hydroxysteroid (17-beta) dehydrogenase 4 |
affects expression |
EXP |
Streptozocin affects the expression of HSD17B4 mRNA |
CTD |
PMID:18583417 |
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NCBI chr18:50,261,268...50,329,337
Ensembl chr18:50,261,268...50,329,336
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G |
Hsd3b3 |
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 |
affects expression |
EXP |
Streptozocin affects the expression of HSD3B3 mRNA |
CTD |
PMID:18583417 |
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NCBI chr 3:98,648,792...98,672,465
Ensembl chr 3:98,648,839...98,670,443
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G |
Hsd3b5 |
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of HSD3B5 mRNA |
CTD |
PMID:29127188 |
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NCBI chr 3:98,525,952...98,552,850
Ensembl chr 3:98,525,950...98,537,568
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G |
Hsd3b6 |
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of HSD3B6 mRNA |
CTD |
PMID:29127188 |
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NCBI chr 3:98,712,820...98,721,759
Ensembl chr 3:98,712,820...98,721,759
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G |
Hsp90aa1 |
heat shock protein 90, alpha (cytosolic), class A member 1 |
increases expression |
ISO |
Streptozocin results in increased expression of HSP90AA1 mRNA |
CTD |
PMID:37081038 |
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NCBI chr12:110,657,470...110,662,829
Ensembl chr12:110,657,039...110,669,162
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G |
Hsp90b1 |
heat shock protein 90, beta (Grp94), member 1 |
multiple interactions increases expression |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of HSP90B1 mRNA streptozocin increases expression of Hsp90b1 protein in heart |
CTD RGD |
PMID:26522834 PMID:36044268 |
RGD:156430337 |
NCBI chr10:86,526,705...86,541,308
Ensembl chr10:86,526,073...86,541,373
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G |
Hspa2 |
heat shock protein 2 |
affects expression |
EXP |
Streptozocin affects the expression of HSPA2 mRNA |
CTD |
PMID:18583417 |
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NCBI chr12:76,450,688...76,453,712
Ensembl chr12:76,450,950...76,453,712
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G |
Hspa5 |
heat shock protein 5 |
multiple interactions decreases expression increases expression increases expression |
ISO EXP |
4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of HSPA5 protein]; [Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of HSPA5 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of HSPA5 mRNA; Bilirubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of HSPA5 mRNA]; Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of HSPA5 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of HSPA5 protein]; moutan cortex inhibits the reaction [Streptozocin results in increased expression of and results in increased secretion of HSPA5 protein]; Streptozocin results in increased expression of and results in increased secretion of HSPA5 protein; Trientine inhibits the reaction [Streptozocin results in decreased expression of HSPA5 protein]; Vitamin B 12 inhibits the reaction [Streptozocin results in increased expression of HSPA5 protein] [Dietary Fats co-treated with Streptozocin] results in increased expression of HSPA5 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of HSPA5 protein; [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of HSPA5 mRNA]; [Streptozocin co-treated with Dietary Fats] results in increased expression of HSPA5 protein; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of HSPA5 mRNA; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of HSPA5 mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of HSPA5 protein]; sulforaphane inhibits the reaction [Streptozocin results in increased expression of HSPA5 protein] streptozocin increases expression of Hspa5 protein in heart |
CTD RGD |
PMID:19634143 PMID:24967692 PMID:26522834 PMID:27664441 PMID:30980806 PMID:33812996 PMID:34801538 PMID:37054934 PMID:38049026 PMID:38282657 PMID:36044268 More...
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RGD:156430337 |
NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559
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G |
Hspa9 |
heat shock protein 9 |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of HSPA9 protein Trientine inhibits the reaction [Streptozocin results in decreased expression of HSPA9 protein] |
CTD |
PMID:19634143 |
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NCBI chr18:35,070,467...35,087,404
Ensembl chr18:35,070,467...35,087,410
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G |
Hspb1 |
heat shock protein 1 |
multiple interactions increases phosphorylation |
ISO |
baicalin inhibits the reaction [Streptozocin results in increased phosphorylation of HSPB1 protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of HSPB1 protein] |
CTD |
PMID:18204486 PMID:34414639 |
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NCBI chr 5:135,916,773...135,918,417
Ensembl chr 5:135,916,773...135,918,417
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G |
Hspd1 |
heat shock protein 1 (chaperonin) |
multiple interactions increases expression decreases expression |
ISO |
Trientine inhibits the reaction [Streptozocin results in decreased expression of HSPD1 protein]; Trientine inhibits the reaction [Streptozocin results in increased expression of HSPD1 protein] |
CTD |
PMID:19634143 PMID:21136691 |
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NCBI chr 1:55,116,992...55,127,402
Ensembl chr 1:55,116,994...55,127,402
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G |
Hspe1 |
heat shock protein 1 (chaperonin 10) |
multiple interactions decreases expression |
ISO |
Trientine inhibits the reaction [Streptozocin results in decreased expression of HSPE1 protein] |
CTD |
PMID:19634143 |
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NCBI chr 1:55,127,307...55,130,476
Ensembl chr 1:55,127,291...55,130,466
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G |
Hspg2 |
perlecan (heparan sulfate proteoglycan 2) |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of HSPG2 protein Trientine inhibits the reaction [Streptozocin results in increased expression of HSPG2 protein] |
CTD |
PMID:19634143 |
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NCBI chr 4:137,196,062...137,297,941
Ensembl chr 4:137,196,080...137,297,941
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G |
Htr1a |
5-hydroxytryptamine (serotonin) receptor 1A |
multiple interactions |
ISO |
Streptozocin inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased activity of HTR1A protein] |
CTD |
PMID:18622176 |
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NCBI chr13:105,580,040...105,584,630
Ensembl chr13:105,580,147...105,584,630
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G |
Htr2a |
5-hydroxytryptamine (serotonin) receptor 2A |
multiple interactions |
ISO |
Streptozocin inhibits the reaction [4-iodo-2,5-dimethoxyphenylisopropylamine results in increased activity of HTR2A protein] |
CTD |
PMID:18622176 |
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NCBI chr14:74,878,314...74,944,299
Ensembl chr14:74,878,280...74,946,934
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G |
Htr2c |
5-hydroxytryptamine (serotonin) receptor 2C |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of HTR2C mRNA |
CTD |
PMID:33484791 |
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NCBI chr X:145,745,509...145,980,273
Ensembl chr X:145,745,509...145,980,273
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G |
Iapp |
islet amyloid polypeptide |
multiple interactions decreases expression |
ISO EXP |
rosiglitazone inhibits the reaction [Streptozocin results in decreased expression of IAPP mRNA] [octylphenol co-treated with Streptozocin] results in decreased expression of IAPP mRNA; Streptozocin inhibits the reaction [Ethinyl Estradiol results in decreased expression of IAPP mRNA] |
CTD |
PMID:18998217 PMID:29935216 |
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NCBI chr 6:142,244,151...142,249,546
Ensembl chr 6:142,244,149...142,249,687
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G |
Icam1 |
intercellular adhesion molecule 1 |
multiple interactions increases expression |
EXP ISO |
AM6545 inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; AM6545 inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]]; Clodronic Acid inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; Curcumin analog inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; dehydroxymethylepoxyquinomicin inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; dehydroxymethylepoxyquinomicin inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; Perindopril inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; Perindopril inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; sulforaphane inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; Telmisartan inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA] Streptozocin results in increased expression of ICAM1 mRNA; Streptozocin results in increased expression of ICAM1 protein [Streptozocin co-treated with Cholesterol, Dietary] results in increased expression of ICAM1 protein; Atorvastatin inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; Atorvastatin inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; candesartan inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; cloricromen inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; fasudil inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Cholesterol, Dietary] results in increased expression of ICAM1 protein]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; moutan cortex inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; Rosiglitazone inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; Rosiglitazone inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein] |
CTD |
PMID:10485912 PMID:14871415 PMID:15892581 PMID:16129698 PMID:16139267 PMID:17589825 PMID:17724226 PMID:19246972 PMID:19279317 PMID:22058332 PMID:23376009 PMID:24513509 PMID:24967692 PMID:27664441 PMID:28700904 PMID:30184259 More...
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NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113
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G |
Id2 |
inhibitor of DNA binding 2 |
decreases expression |
ISO |
Streptozocin results in decreased expression of ID2 mRNA |
CTD |
PMID:25905778 |
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NCBI chr12:25,143,798...25,146,091
Ensembl chr12:25,143,798...25,147,139
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G |
Idh2 |
isocitrate dehydrogenase 2 (NADP+), mitochondrial |
affects expression |
EXP |
Streptozocin affects the expression of IDH2 mRNA |
CTD |
PMID:18583417 |
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NCBI chr 7:79,744,594...79,768,356
Ensembl chr 7:79,744,594...79,765,140
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G |
Ifitm3 |
interferon induced transmembrane protein 3 |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of IFITM3 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 7:140,589,503...140,590,657
Ensembl chr 7:140,589,499...140,590,683
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G |
Ifng |
interferon gamma |
multiple interactions increases expression decreases expression |
EXP ISO |
Clodronic Acid inhibits the reaction [Streptozocin results in increased expression of IFNG protein]; Dronabinol inhibits the reaction [Streptozocin results in increased expression of IFNG mRNA]; S-Nitroso-N-Acetylpenicillamine inhibits the reaction [Streptozocin results in increased expression of IFNG protein]; Sodium Selenite inhibits the reaction [Streptozocin results in increased expression of IFNG mRNA] Streptozocin results in increased expression of IFNG mRNA; Streptozocin results in increased expression of IFNG protein arjunolic acid inhibits the reaction [Streptozocin results in decreased expression of IFNG protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of IFNG protein] |
CTD |
PMID:11357882 PMID:15862027 PMID:15892581 PMID:15975818 PMID:18789669 PMID:20053369 PMID:25541178 More...
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NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
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G |
Igdcc4 |
immunoglobulin superfamily, DCC subclass, member 4 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of IGDCC4 mRNA |
CTD |
PMID:33484791 |
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NCBI chr 9:65,008,246...65,045,225
Ensembl chr 9:65,008,768...65,045,222
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G |
Igf1 |
insulin-like growth factor 1 |
multiple interactions decreases expression increases expression |
EXP ISO |
[Dietary Fats co-treated with Streptozocin] results in increased expression of IGF1 mRNA; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IGF1 mRNA]; IGF1 protein inhibits the reaction [Streptozocin results in increased expression of AGT protein]; IGF1 protein inhibits the reaction [Streptozocin results in increased expression of BAX protein]; IGF1 protein inhibits the reaction [Streptozocin results in increased expression of TRP53 protein]; Metformin inhibits the reaction [Streptozocin results in decreased expression of IGF1 protein]; puerarin inhibits the reaction [Streptozocin results in decreased expression of IGF1 protein] Streptozocin results in decreased expression of IGF1 mRNA; Streptozocin results in decreased expression of IGF1 protein Streptozocin results in increased expression of IGF1 protein [Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IGF1 protein]; [Streptozocin co-treated with Dietary Fats] results in increased expression of IGF1 protein; Dimethyl Fumarate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IGF1 protein]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IGF1 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IGF1 protein]; Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of IGF1 protein]; Rivastigmine inhibits the reaction [Streptozocin results in decreased expression of IGF1 protein]; Wortmannin inhibits the reaction [Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of IGF1 protein]] |
CTD |
PMID:7637645 PMID:9868179 PMID:11375343 PMID:23927877 PMID:25617479 PMID:32805344 PMID:33359794 PMID:36999408 More...
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NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904
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G |
Igf1r |
insulin-like growth factor I receptor |
decreases expression multiple interactions |
ISO EXP |
Streptozocin results in decreased expression of IGF1R protein [Dietary Fats co-treated with Streptozocin co-treated with Ovalbumin] results in decreased expression of IGF1R mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Ovalbumin] results in decreased expression of IGF1R protein; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin co-treated with Ovalbumin] results in decreased expression of IGF1R mRNA]; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin co-treated with Ovalbumin] results in decreased expression of IGF1R protein]; xanthoceraside inhibits the reaction [Streptozocin results in decreased expression of IGF1R protein] [Streptozocin co-treated with CNR1 protein] affects the expression of IGF1R protein |
CTD |
PMID:23562514 PMID:30721768 PMID:36547818 |
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NCBI chr 7:67,601,486...67,883,416
Ensembl chr 7:67,602,575...67,883,416
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G |
Igf2bp3 |
insulin-like growth factor 2 mRNA binding protein 3 |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in decreased expression of IGF2BP3 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 6:49,062,152...49,200,225
Ensembl chr 6:49,062,157...49,191,891
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G |
Igf2r |
insulin-like growth factor 2 receptor |
multiple interactions increases expression increases response to substance |
ISO |
[IGF2R protein alternative form results in increased susceptibility to Streptozocin] which results in increased abundance of Cholesterol; [IGF2R protein alternative form results in increased susceptibility to Streptozocin] which results in increased abundance of Triglycerides; [Streptozocin co-treated with IGF2R protein modified form] results in increased expression of CASP3 protein modified form; IGF2R protein modified form inhibits the reaction [Streptozocin results in increased expression of CASP9 protein]; IGF2R protein modified form promotes the reaction [Streptozocin results in decreased expression of BCL2 protein]; IGF2R protein modified form promotes the reaction [Streptozocin results in decreased expression of NFKBIA protein modified form]; IGF2R protein modified form promotes the reaction [Streptozocin results in increased expression of IL1B protein]; IGF2R protein modified form promotes the reaction [Streptozocin results in increased expression of PTGS2 protein]; IGF2R protein modified form promotes the reaction [Streptozocin results in increased expression of RELA protein modified form]; IGF2R protein modified form promotes the reaction [Streptozocin results in increased expression of TNF protein]; Streptozocin promotes the reaction [IGF2R protein alternative form results in increased abundance of Triglycerides]; Streptozocin promotes the reaction [IGF2R protein modified form results in decreased expression of BCL2 protein modified form]; Streptozocin promotes the reaction [IGF2R protein modified form results in decreased expression of NFKBIA protein modified form]; Streptozocin promotes the reaction [IGF2R protein modified form results in increased expression of IL6 protein]; Streptozocin promotes the reaction [IGF2R protein modified form results in increased expression of RELA protein modified form] Streptozocin results in increased expression of IGF2R protein |
CTD |
PMID:35993117 PMID:36462176 |
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NCBI chr17:12,901,293...12,988,593
Ensembl chr17:12,901,293...12,988,551
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G |
Igfbp1 |
insulin-like growth factor binding protein 1 |
multiple interactions |
EXP |
[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of IGFBP1 mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of IGFBP1 protein; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of IGFBP1 mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of IGFBP1 protein] |
CTD |
PMID:39047806 |
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NCBI chr11:7,147,787...7,152,546
Ensembl chr11:7,147,782...7,152,546
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G |
Igfbp2 |
insulin-like growth factor binding protein 2 |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of IGFBP2 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 1:72,863,650...72,891,633
Ensembl chr 1:72,863,662...72,891,633
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G |
Igfbp3 |
insulin-like growth factor binding protein 3 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of IGFBP3 mRNA 2-amino-6-boronohexanoic acid inhibits the reaction [Streptozocin results in increased expression of IGFBP3 mRNA] |
CTD |
PMID:29673160 |
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NCBI chr11:7,156,086...7,165,498
Ensembl chr11:7,156,086...7,163,923
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G |
Igfbp7 |
insulin-like growth factor binding protein 7 |
increases expression |
EXP |
Streptozocin results in increased expression of IGFBP7 mRNA |
CTD |
PMID:29673160 |
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NCBI chr 5:77,497,092...77,555,892
Ensembl chr 5:77,497,087...77,555,888
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G |
Igsf6 |
immunoglobulin superfamily, member 6 |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of IGSF6 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 7:120,663,290...120,673,753
Ensembl chr 7:120,663,290...120,673,795
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G |
Ikbkb |
inhibitor of kappaB kinase beta |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of IKBKB protein; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of IKBKB protein] |
CTD |
PMID:34610774 |
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NCBI chr 8:23,149,228...23,196,605
Ensembl chr 8:23,149,228...23,196,605
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G |
Il10 |
interleukin 10 |
decreases expression multiple interactions increases expression |
EXP ISO |
Streptozocin results in decreased expression of IL10 mRNA [Streptozocin co-treated with Dietary Fats] results in decreased expression of IL10 protein; [Streptozocin co-treated with Sodium Glutamate] results in increased expression of IL10 protein; [Vanadium co-treated with Selenium co-treated with Vitamin E co-treated with Chromium] inhibits the reaction [Streptozocin results in decreased expression of IL10 protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of IL10 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of IL10 protein]; Metformin inhibits the reaction [Streptozocin results in decreased expression of IL10 protein]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of IL10 mRNA]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of IL10 protein] Streptozocin results in decreased expression of IL10 mRNA; Streptozocin results in decreased expression of IL10 protein Streptozocin results in increased expression of IL10 mRNA 2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of IL10 mRNA]; 2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of IL10 protein]; [Streptozocin co-treated with Niacinamide] results in decreased expression of IL10 mRNA; [Streptozocin co-treated with Niacinamide] results in decreased expression of IL10 protein; Chlorpyrifos inhibits the reaction [Streptozocin results in increased expression of IL10 mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of IL10 mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of IL10 protein] Streptozocin results in increased expression of IL10 protein |
CTD |
PMID:15862027 PMID:32662907 PMID:33524429 PMID:33639173 PMID:35085591 PMID:37120126 PMID:38084638 More...
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NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
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G |
Il12b |
interleukin 12b |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of IL12B mRNA Dronabinol inhibits the reaction [Streptozocin results in increased expression of IL12B mRNA] |
CTD |
PMID:11357882 |
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NCBI chr11:44,290,890...44,305,504
Ensembl chr11:44,290,890...44,304,860
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G |
Il17a |
interleukin 17A |
multiple interactions increases expression |
ISO |
stannous mesoporphyrin inhibits the reaction [4-(4-(3-adamantan-1-ylureido)cyclohexyloxy)benzoic acid inhibits the reaction [Streptozocin results in increased expression of IL17A protein]] |
CTD |
PMID:23611540 |
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NCBI chr 1:20,801,129...20,804,720
Ensembl chr 1:20,801,129...20,804,720
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G |
Il18 |
interleukin 18 |
multiple interactions increases expression |
ISO EXP |
[Streptozocin co-treated with Niacinamide co-treated with ENV-2 compound] results in decreased expression of IL18 mRNA; Allopurinol inhibits the reaction [Streptozocin results in increased expression of IL18 protein]; nifuroxazide inhibits the reaction [Streptozocin results in increased expression of IL18 mRNA]; palbinone inhibits the reaction [Streptozocin results in increased expression of IL18 protein]; Quercetin inhibits the reaction [Streptozocin results in increased expression of IL18 protein]; scutellarin inhibits the reaction [Streptozocin results in increased expression of IL18 protein] Streptozocin results in increased expression of IL18 mRNA; Streptozocin results in increased expression of IL18 protein [Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of IL18 protein; [Dietary Fats co-treated with Streptozocin] results in increased expression of IL18 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of IL18 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of IL18 protein; aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL18 protein]; GSDMD protein affects the reaction [Streptozocin results in increased expression of IL18 protein]; Hirudins inhibits the reaction [Streptozocin results in increased expression of IL18 protein]; loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of IL18 protein]; loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL18 mRNA] |
CTD |
PMID:23647015 PMID:28322830 PMID:29291386 PMID:32202043 PMID:34212273 PMID:35961541 PMID:37081038 PMID:37473909 More...
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NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140
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G |
Il1a |
interleukin 1 alpha |
multiple interactions |
EXP |
[Streptozocin co-treated with bisphenol A] results in increased expression of IL1A mRNA; [Streptozocin co-treated with Ethinyl Estradiol] results in increased expression of IL1A mRNA; [Streptozocin co-treated with octylphenol] results in increased expression of IL1A mRNA |
CTD |
PMID:24781736 |
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NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892
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G |
Il1b |
interleukin 1 beta |
multiple interactions increases expression decreases expression |
ISO EXP |
PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA] [Chlorpyrifos co-treated with Streptozocin] results in increased expression of IL1B mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of IL1B protein; [Streptozocin co-treated with Dextran Sulfate] results in increased expression of IL1B protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B protein; [Streptozocin co-treated with Dietary Fats] results in increased secretion of IL1B protein; Acrylamide inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; Alendronate inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Ascorbic Acid inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; asiatic acid inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; asiatic acid promotes the reaction [Carnosine inhibits the reaction [Streptozocin results in increased expression of IL1B protein]]; aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B mRNA]; aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B protein]; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased secretion of IL1B protein]; Carnosine inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Donepezil inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Genistein inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; GSDMD protein affects the reaction [Streptozocin results in increased expression of IL1B protein]; Hirudins inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of IL1B protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; montelukast inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Sodium Selenite inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA] Streptozocin results in increased expression of IL1B mRNA; Streptozocin results in increased expression of IL1B protein 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL1B protein]; [Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in increased expression of IL1B protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of IL1B protein; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of IL1B protein; [Niacinamide co-treated with Streptozocin] results in increased expression of IL1B protein; [pimagedine co-treated with Fatty Acids, Omega-3] inhibits the reaction [Streptozocin results in increased expression of and results in increased secretion of IL1B protein]; [Resveratrol co-treated with Streptozocin] results in increased expression of IL1B mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B protein; [Streptozocin co-treated with Niacinamide co-treated with ENV-2 compound] results in decreased expression of IL1B mRNA; [Streptozocin co-treated with Niacinamide] results in increased expression of IL1B protein; [Streptozocin co-treated with Sodium Glutamate] results in increased expression of IL1B protein; Allopurinol inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Atorvastatin inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of IL1B protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of IL1B protein]; Diosgenin inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; Diosgenin inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of IL1B protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B protein]; Enalapril inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; Gallic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B protein]; Gliclazide inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in increased expression of IL1B protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of IL1B protein]; Gliclazide inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of IL1B protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; Glyburide inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; IGF2R protein modified form promotes the reaction [Streptozocin results in increased expression of IL1B protein]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B protein]; Metformin inhibits the reaction [Streptozocin results in decreased expression of IL1B protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in increased expression of IL1B protein]]; myrtenol inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; palbinone inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Pentoxifylline inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; pinitol inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Plant Extracts inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Resveratrol inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in increased expression of IL1B protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of IL1B protein]; Streptozocin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of IL1B mRNA]; Streptozocin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of IL1B protein]; Streptozocin results in increased expression of and results in increased secretion of IL1B protein; STUB1 inhibits the reaction [Streptozocin results in increased phosphorylation of IL1B protein]; sulbutiamine inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Tropisetron inhibits the reaction [Streptozocin results in increased expression of IL1B protein] |
CTD |
PMID:12123627 PMID:16129698 PMID:17167242 PMID:17589825 PMID:18789669 PMID:20307516 PMID:20446767 PMID:20643114 PMID:21439372 PMID:23647015 PMID:24877639 PMID:25541178 PMID:25635252 PMID:25905778 PMID:26341651 PMID:27702591 PMID:28259689 PMID:28322830 PMID:30481507 PMID:30611788 PMID:30642005 PMID:30802477 PMID:30817903 PMID:31726037 PMID:32202043 PMID:33524429 PMID:33639173 PMID:34212273 PMID:34477272 PMID:34896238 PMID:34964214 PMID:35085591 PMID:35305976 PMID:35442559 PMID:35961541 PMID:36462176 PMID:36504472 PMID:36510688 PMID:36547818 PMID:37224990 PMID:37473909 PMID:37482253 PMID:38084638 More...
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NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
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G |
Il1rl1 |
interleukin 1 receptor-like 1 |
multiple interactions |
ISO |
7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL1RL1 mRNA]; [Dietary Fats co-treated with Streptozocin] results in increased expression of IL1RL1 mRNA |
CTD |
PMID:31726037 |
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NCBI chr 1:40,444,105...40,504,575
Ensembl chr 1:40,468,730...40,504,575
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G |
Il1rn |
interleukin 1 receptor antagonist |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of IL1RN mRNA |
CTD |
PMID:29127188 |
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NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506
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G |
Il2 |
interleukin 2 |
multiple interactions decreases expression |
ISO |
arjunolic acid inhibits the reaction [Streptozocin results in decreased expression of IL2 protein] |
CTD |
PMID:20053369 |
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NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108
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G |
Il22b |
interleukin 22B |
multiple interactions |
EXP |
IL22 protein inhibits the reaction [Streptozocin results in increased abundance of Glucose] |
CTD |
PMID:26064446 |
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NCBI chr10:118,125,534...118,130,943
Ensembl chr10:118,125,534...118,130,943
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G |
Il23a |
interleukin 23, alpha subunit p19 |
multiple interactions increases expression |
EXP |
5-Methoxypsoralen inhibits the reaction [Streptozocin results in increased expression of IL23A protein]; Tadalafil inhibits the reaction [Streptozocin results in increased expression of IL23A protein] |
CTD |
PMID:34428446 |
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NCBI chr10:128,132,009...128,133,953
Ensembl chr10:128,132,008...128,134,621
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G |
Il27 |
interleukin 27 |
multiple interactions increases expression |
EXP |
5-Methoxypsoralen inhibits the reaction [Streptozocin results in increased expression of IL27 protein]; Tadalafil inhibits the reaction [Streptozocin results in increased expression of IL27 protein] |
CTD |
PMID:34428446 |
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NCBI chr 7:126,188,181...126,194,197
Ensembl chr 7:126,188,182...126,194,113
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G |
Il33 |
interleukin 33 |
multiple interactions |
ISO |
7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL33 mRNA]; 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL33 protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of IL33 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of IL33 protein |
CTD |
PMID:31726037 |
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NCBI chr19:29,902,513...29,938,118
Ensembl chr19:29,902,514...29,938,118
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G |
Il4 |
interleukin 4 |
multiple interactions decreases expression |
ISO |
resveratrol inhibits the reaction [Streptozocin results in decreased expression of IL4] |
CTD |
PMID:25191525 |
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NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
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G |
Il6 |
interleukin 6 |
increases expression increases secretion multiple interactions decreases expression |
ISO EXP |
Streptozocin results in increased expression of IL6 mRNA; Streptozocin results in increased expression of IL6 protein Streptozocin results in increased secretion of IL6 protein 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; 4-methyl-2-((2-methylbenzyl) amino)-1,3-thiazole-5-carboxylic acid inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL6 protein]; 7-hydroxycoumarin inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; [Dietary Fats co-treated with Streptozocin co-treated with Plant Extracts] affects the expression of IL6 protein; [Dietary Fats co-treated with Streptozocin co-treated with Quercetin] affects the expression of IL6 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Quercetin] affects the expression of IL6 protein; [Dietary Fats co-treated with Streptozocin] results in increased expression of IL6 protein; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of IL6 protein; [Niacinamide co-treated with Streptozocin] results in increased expression of IL6 protein; [Propolis co-treated with Streptozocin co-treated with Chlorpyrifos] results in increased secretion of IL6 protein; [Propolis co-treated with Streptozocin] results in increased secretion of IL6 protein; [Streptozocin co-treated with Chlorpyrifos] results in increased secretion of IL6 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of IL6 protein; [Streptozocin co-treated with Niacinamide] results in increased expression of IL6 protein; [Streptozocin co-treated with Sodium Glutamate] results in increased expression of IL6 protein; Acetylcysteine inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Allopurinol inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of IL6 protein]; caryophyllene inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; crocin inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Diosgenin inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; Diosgenin inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Dronabinol inhibits the reaction [Streptozocin results in decreased expression of IL6 protein]; Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL6 protein]; Enalapril inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; Flavonoids inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Gallic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL6 protein]; Gliclazide inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in increased expression of IL6 protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of IL6 protein]; Gliclazide inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of IL6 protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; Glyburide inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; hesperetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL6 protein]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; mangiferin inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Melatonin inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL6 protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; Metformin inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; moutan cortex inhibits the reaction [Streptozocin results in increased expression of and results in increased secretion of IL6 protein]; Pentoxifylline inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; pinitol inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; piperlongumine inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; piperlongumine inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Plant Extracts inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL6 protein]; Propolis inhibits the reaction [[Streptozocin co-treated with Chlorpyrifos] results in increased secretion of IL6 protein]; Propolis inhibits the reaction [Streptozocin results in increased secretion of IL6 protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL6 protein]; Resveratrol inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in increased expression of IL6 protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of IL6 protein]; SMe1EC2 promotes the reaction [Streptozocin results in increased expression of IL6 protein]; Streptozocin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of IL6 mRNA]; Streptozocin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of IL6 protein]; Streptozocin promotes the reaction [IGF2R protein modified form results in increased expression of IL6 protein]; Streptozocin results in increased expression of and results in increased secretion of IL6 protein 3-((6-(2-methoxyphenyl)pyrimidin-4-yl)amino)phenyl)methane sulfonamide inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; [Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of IL6 protein; [Dietary Fats co-treated with Streptozocin] results in increased expression of IL6 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of IL6 protein; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of IL6 mRNA; [Streptozocin co-treated with Dextran Sulfate] results in increased expression of IL6 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of IL6 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased secretion of IL6 protein; Acrylamide inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; Alendronate inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; asiatic acid inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; asiatic acid promotes the reaction [Carnosine inhibits the reaction [Streptozocin results in increased expression of IL6 protein]]; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased secretion of IL6 protein]; Carnosine inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Carnosine promotes the reaction [asiatic acid inhibits the reaction [Streptozocin results in increased expression of IL6 protein]]; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Curcumin analog inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; Donepezil inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; esculetin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL6 mRNA]; esculetin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL6 protein]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of IL6 protein]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of IL6 mRNA]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL6 mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of IL6 protein] |
CTD |
PMID:17167242 PMID:17854708 PMID:18999900 PMID:20307516 PMID:20643114 PMID:21439094 PMID:21439372 PMID:21457706 PMID:21912612 PMID:24760747 PMID:24877639 PMID:26341651 PMID:26748309 PMID:27664441 PMID:27769711 PMID:28700904 PMID:28904557 PMID:29181404 PMID:29233026 PMID:29266779 PMID:29409856 PMID:29988851 PMID:30481507 PMID:30611788 PMID:30642005 PMID:30802477 PMID:30817903 PMID:31323227 PMID:31400774 PMID:31696645 PMID:31726037 PMID:32554039 PMID:33631230 PMID:33639173 PMID:33724628 PMID:34610774 PMID:34896238 PMID:34922902 PMID:34964214 PMID:35085591 PMID:35305976 PMID:36462176 PMID:36510688 PMID:36650709 PMID:37044004 PMID:37482253 PMID:38084638 PMID:39047806 More...
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NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
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G |
Il6st |
interleukin 6 signal transducer |
affects expression |
EXP |
Streptozocin affects the expression of IL6ST mRNA |
CTD |
PMID:26073000 |
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NCBI chr13:112,600,604...112,643,394
Ensembl chr13:112,600,604...112,646,620
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G |
Ilk |
integrin linked kinase |
multiple interactions increases activity |
ISO |
notoginsenoside R1 inhibits the reaction [Streptozocin results in increased activity of ILK protein] |
CTD |
PMID:25503068 |
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NCBI chr 7:105,385,797...105,392,132
Ensembl chr 7:105,385,799...105,392,132
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G |
Impa2 |
inositol monophosphatase 2 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of IMPA2 mRNA vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of IMPA2 mRNA] |
CTD |
PMID:16684804 |
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NCBI chr18:67,422,246...67,454,375
Ensembl chr18:67,422,256...67,455,542
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G |
Inava |
innate immunity activator |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of INAVA mRNA |
CTD |
PMID:33484791 |
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NCBI chr 1:136,141,259...136,162,045
Ensembl chr 1:136,141,269...136,162,002
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G |
Inhbb |
inhibin beta-B |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of INHBB mRNA |
CTD |
PMID:29127188 |
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NCBI chr 1:119,343,193...119,349,978
Ensembl chr 1:119,343,195...119,349,978
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G |
Inpp5k |
inositol polyphosphate 5-phosphatase K |
multiple interactions |
EXP |
[Dietary Fats co-treated with Streptozocin] results in increased expression of INPP5K mRNA; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of INPP5K mRNA] |
CTD |
PMID:33812996 |
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NCBI chr11:75,519,893...75,539,691
Ensembl chr11:75,521,814...75,539,697
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G |
Ins1 |
insulin I |
multiple interactions decreases expression decreases secretion increases secretion decreases response to substance increases expression |
EXP ISO |
[1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of and results in decreased secretion of INS1 protein]; [Carnosine co-treated with asiatic acid] inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of and results in decreased secretion of INS1 protein; [Dietary Fats co-treated with Streptozocin] results in decreased expression of INS1 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of INS1 protein; [Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of INS1 protein; [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of INS1 protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of INS1 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of INS1 protein; [Streptozocin co-treated with INS1 protein co-treated with Glutathione] affects the expression of CAT mRNA; [Streptozocin co-treated with INS1 protein co-treated with Glutathione] affects the expression of SOD2 mRNA; AM 251 inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; asiatic acid inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; bisphenol A inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; Carnosine inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; CNR1 protein promotes the reaction [Streptozocin results in decreased expression of INS1 protein]; Dronabinol inhibits the reaction [Streptozocin results in decreased expression of INS1]; Edaravone inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; Ethinyl Estradiol inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of INS1 mRNA]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of INS1 protein]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of INS1 protein]; Glyburide inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; INS1 inhibits the reaction [[Streptozocin co-treated with APOE mutant form] results in increased abundance of Glucosamine]; INS1 protein affects the reaction [Streptozocin results in decreased methylation of PPP2CA protein]; INS1 protein inhibits the reaction [Streptozocin results in decreased expression of DNMT1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of POU1F1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of POU1F1 protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of SLC20A2 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of SLC20A2 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of INS1 protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; octylphenol inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; PQQ Cofactor inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; pterostilbene inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of INS1 protein]; Streptozocin inhibits the reaction [Glucose results in increased secretion of INS1 protein]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of INS1 protein] Streptozocin results in decreased expression of INS1; Streptozocin results in decreased expression of INS1 protein Streptozocin results in increased secretion of INS1 protein Streptozocin results in decreased expression of INS1 protein; Streptozocin results in decreased expression of INS1 protein modified form ALPK1 protein promotes the reaction [Streptozocin results in decreased secretion of INS1 protein] Streptozocin results in decreased susceptibility to INS1 protein Streptozocin results in increased expression of INS1 mRNA; Streptozocin results in increased expression of INS1 protein 4-hydroxyisoleucine inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; 4-hydroxyphenylethanol inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; 4-methyl-2-((2-methylbenzyl) amino)-1,3-thiazole-5-carboxylic acid inhibits the reaction [Streptozocin results in increased expression of INS1 protein]; 7-hydroxycoumarin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of INS1 protein; [Dietary Fats co-treated with Streptozocin] results in decreased secretion of INS1 protein; [Dietary Fats co-treated with Streptozocin] results in increased secretion of INS1 protein; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of INS1 protein; [INS1 protein co-treated with Pravastatin] inhibits the reaction [Streptozocin results in decreased expression of ACE2 protein]; [INS1 protein co-treated with Pravastatin] inhibits the reaction [Streptozocin results in increased expression of ACE protein]; [Niacinamide co-treated with Streptozocin] results in decreased expression of INS1 protein; [Plant Extracts co-treated with glimepiride] inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; [Propolis co-treated with Chlorpyrifos] inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; [Propolis co-treated with Streptozocin co-treated with Chlorpyrifos] results in decreased secretion of INS1 protein; [Propolis co-treated with Streptozocin] promotes the reaction [Chlorpyrifos results in decreased expression of INS1 protein]; [Propolis co-treated with Streptozocin] promotes the reaction [Chlorpyrifos results in decreased secretion of INS1 protein]; [Propolis co-treated with Streptozocin] results in decreased secretion of INS1 protein; [Streptozocin co-treated with Cadmium] results in decreased expression of INS1 protein; [Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in increased expression of INS1 protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of INS1 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of INS1 protein; [Streptozocin co-treated with Fructose] results in increased expression of INS1 protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of INS1 protein; [Streptozocin co-treated with Niacinamide] results in decreased secretion of INS1 protein; [Streptozocin co-treated with Niacinamide] results in increased expression of INS1 protein; [Streptozocin co-treated with Sodium Glutamate] results in decreased expression of INS1 protein; Acetates inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of INS1 protein]; allyl isothiocyanate inhibits the reaction [Streptozocin promotes the reaction [Dietary Fats results in increased expression of INS1 protein]]; anthranilic acid analog inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; asiatic acid inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; baicalin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of INS1 protein]; Butyric Acid inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; carvacrol affects the reaction [Streptozocin results in decreased expression of INS1 protein]; caryophyllene inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; chebulagic acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of INS1 protein]; Chlorpyrifos inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; citronellol inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; corilagin inhibits the reaction [Streptozocin results in increased secretion of INS1 protein]; costunolide inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; coumarin inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in decreased expression of INS1 protein]; coumarin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of INS1 protein]; crocin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; Diosgenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of INS1 protein]; Diosgenin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; Estradiol inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; eupafolin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of INS1 protein]; Ficusin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of INS1 protein]; geraniol inhibits the reaction [Streptozocin results in decreased expression of and results in decreased secretion of INS1 protein]; Gliclazide inhibits the reaction [Streptozocin results in decreased expression of and results in decreased secretion of INS1 protein]; Gliclazide inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; glimepiride inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of INS1 protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of INS1 protein]; Glyburide inhibits the reaction [Streptozocin results in increased secretion of INS1 protein]; Imatinib Mesylate inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; INS1 protein inhibits the reaction [Streptozocin results in decreased expression of GAD1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in decreased expression of GPX1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in decreased expression of SLC1A3 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased activity of CAT protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of CASP8 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of COL3A1 protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of CYP8B1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of GRIA4 protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of GRIN1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of GRIN1 protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of MMP2 protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of MMP9 protein]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of INS1 protein]; Lithium Carbonate inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; mangiferin inhibits the reaction [Streptozocin results in increased expression of INS1 protein]; Melatonin affects the reaction [Streptozocin results in decreased expression of INS1 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in increased expression of INS1 protein]; Metformin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; morin analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of INS1 protein]; morin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased expression of INS1 protein]; myrtenal inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; nerolidol inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of INS1 protein]; palbinone inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; Phosphocreatine inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; Pioglitazone inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of INS1 protein]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of INS1 protein]; Plant Extracts inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased secretion of INS1 protein]; Plant Extracts inhibits the reaction [[Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in increased expression of INS1 protein]; Plant Extracts inhibits the reaction [Streptozocin results in decreased expression of and results in decreased secretion of INS1 protein]; Plant Extracts inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; Plant Extracts inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; plumbagin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; Polysaccharides inhibits the reaction [Streptozocin results in decreased expression of and results in decreased secretion of INS1 protein]; Propolis inhibits the reaction [[Streptozocin co-treated with Chlorpyrifos] results in decreased secretion of INS1 protein]; Propolis inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of INS1 protein]; repaglinide analog affects the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of INS1 protein]; repaglinide inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of INS1 protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of INS1 protein]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; Rosiglitazone promotes the reaction [Streptozocin inhibits the reaction [Dietary Fats results in increased expression of INS1 protein]]; S-allylcysteine inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; Streptozocin affects the reaction [Chlorpyrifos results in decreased secretion of INS1 protein]; Streptozocin inhibits the reaction [Blood Glucose results in increased secretion of INS1 protein]; Streptozocin inhibits the reaction [Dietary Fats results in increased expression of INS1 protein]; Streptozocin promotes the reaction [Dietary Fats results in increased expression of INS1 protein]; Streptozocin results in decreased expression of and results in decreased secretion of INS1 protein; thymoquinone inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of INS1 protein]; thymoquinone inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased secretion of INS1 protein]; TRH protein inhibits the reaction [Streptozocin inhibits the reaction [Blood Glucose results in increased secretion of INS1 protein]]; Tribulus extract inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; Warfarin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased secretion of INS1 protein]; Zinc Compounds inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of INS1 protein] |
CTD |
PMID:6337899 PMID:7564366 PMID:9868179 PMID:10393316 PMID:10700396 PMID:11357483 PMID:11357882 PMID:11766996 PMID:16118471 PMID:16380481 PMID:18291360 PMID:18998217 PMID:19007766 PMID:19071154 PMID:19647726 PMID:20711301 PMID:20801139 PMID:20951120 PMID:21382363 PMID:21630391 PMID:21799698 PMID:22675305 PMID:22960630 PMID:23267840 PMID:23884884 PMID:24001619 PMID:24530320 PMID:24854284 PMID:24923654 PMID:25362599 PMID:25446853 PMID:25541178 PMID:25617479 PMID:25635252 PMID:25641191 PMID:25999625 PMID:26064446 PMID:26071184 PMID:26286522 PMID:26343954 PMID:26522834 PMID:26616445 PMID:26700463 PMID:26721197 PMID:26748309 PMID:26944432 PMID:26967640 PMID:27038876 PMID:27350165 PMID:27417257 PMID:27488359 PMID:27542954 PMID:27769711 PMID:28330423 PMID:28422052 PMID:28625491 PMID:29216956 PMID:29233026 PMID:29274332 PMID:29409856 PMID:29441829 PMID:29614383 PMID:29682576 PMID:29935216 PMID:29953732 PMID:29988851 PMID:30582900 PMID:30802477 PMID:30817903 PMID:30927557 PMID:31400774 PMID:31877369 PMID:32153207 PMID:32202043 PMID:32410268 PMID:32554039 PMID:32662907 PMID:32710900 PMID:33359794 PMID:33450223 PMID:33484791 PMID:33724628 PMID:34352274 PMID:34414639 PMID:34455488 PMID:34470562 PMID:34656705 PMID:35072544 PMID:35305976 PMID:35414346 PMID:35457000 PMID:35702883 PMID:36169646 PMID:36510688 PMID:36627075 PMID:36650709 PMID:37044004 PMID:37337224 PMID:37566541 PMID:38049026 PMID:38084638 PMID:39299373 More...
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NCBI chr19:52,252,735...52,253,453
Ensembl chr19:52,252,735...52,253,914
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G |
Ins2 |
insulin II |
multiple interactions decreases expression |
ISO EXP |
INS protein inhibits the reaction [Streptozocin results in decreased expression of NES mRNA]; Resveratrol inhibits the reaction [Streptozocin inhibits the reaction [INS protein results in increased phosphorylation of INSR protein]]; Streptozocin inhibits the reaction [INS protein results in increased phosphorylation of INSR protein] [Dietary Fats co-treated with Streptozocin] results in decreased expression of INS2 mRNA; [Diethylhexyl Phthalate co-treated with Streptozocin co-treated with Dietary Fats] results in increased expression of INS2 mRNA; [Glyburide co-treated with Streptozocin] results in increased secretion of INS protein; [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of INS2 protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of INS2 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of INS2 mRNA]; INS protein inhibits the reaction [Streptozocin results in decreased activity of SOD3 protein]; INS protein inhibits the reaction [Streptozocin results in decreased expression of ATP7A protein] Streptozocin results in decreased expression of INS protein [Berberine co-treated with Streptozocin] results in increased secretion of INS protein; INS protein inhibits the reaction [Streptozocin results in decreased expression of FASN mRNA]; INS protein inhibits the reaction [Streptozocin results in decreased expression of POMC mRNA]; INS protein inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]; INS protein inhibits the reaction [Streptozocin results in increased expression of AGRP mRNA]; INS protein inhibits the reaction [Streptozocin results in increased expression of NPY mRNA]; INS protein promotes the reaction [Streptozocin results in decreased activity of SOD2 protein]; INS protein promotes the reaction [Streptozocin results in increased activity of GSR protein]; INS protein promotes the reaction [Streptozocin results in increased expression of PPARG mRNA] |
CTD |
PMID:11216864 PMID:15066220 PMID:19388005 PMID:20219977 PMID:22940631 PMID:23884884 PMID:25808216 PMID:33359794 PMID:33484791 More...
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NCBI chr 7:142,232,393...142,233,463
Ensembl chr 7:142,232,393...142,297,118
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G |
Insig1 |
insulin induced gene 1 |
multiple interactions |
EXP |
[Dietary Fats co-treated with Streptozocin] results in increased expression of INSIG1 mRNA |
CTD |
PMID:33359794 |
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NCBI chr 5:28,276,410...28,283,660
Ensembl chr 5:28,276,361...28,283,660
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G |
Insig2 |
insulin induced gene 2 |
decreases expression |
ISO |
Streptozocin results in decreased expression of INSIG2 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 1:121,232,082...121,260,391
Ensembl chr 1:121,232,082...121,260,318
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G |
Insr |
insulin receptor |
affects expression decreases expression decreases phosphorylation increases expression multiple interactions increases expression |
ISO EXP |
Streptozocin affects the expression of INSR protein Streptozocin results in decreased expression of INSR mRNA; Streptozocin results in decreased expression of INSR protein Streptozocin results in decreased phosphorylation of INSR protein Streptozocin results in increased expression of INSR mRNA [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of INSR protein]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of INSR mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of INSR protein; [Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of INSR protein; Metformin inhibits the reaction [Streptozocin results in decreased expression of INSR mRNA]; puerarin inhibits the reaction [Streptozocin results in decreased expression of INSR mRNA] resveratrol inhibits the reaction [Streptozocin inhibits the reaction [INS protein results in increased phosphorylation of INSR protein]]; Streptozocin inhibits the reaction [INS protein results in increased phosphorylation of INSR protein] [Dietary Fats co-treated with Streptozocin co-treated with Ovalbumin] results in decreased expression of INSR mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Ovalbumin] results in decreased expression of INSR protein; [Dietary Fats co-treated with Streptozocin co-treated with Quercetin] affects the expression of INSR mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of INSR mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of INSR protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of INSR protein; asiatic acid inhibits the reaction [Streptozocin results in decreased expression of INSR protein]; Estradiol affects the reaction [Streptozocin affects the expression of INSR protein]; eupafolin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of INSR protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of INSR protein]; Melatonin inhibits the reaction [Streptozocin results in decreased expression of INSR protein]; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin co-treated with Ovalbumin] results in decreased expression of INSR mRNA]; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin co-treated with Ovalbumin] results in decreased expression of INSR protein]; Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of INSR mRNA]; Plant Extracts inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of INSR mRNA]; Plant Extracts inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of INSR protein]; Progesterone affects the reaction [Streptozocin affects the expression of INSR protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of INSR protein]; Rivastigmine inhibits the reaction [Streptozocin results in decreased expression of INSR mRNA]; Wortmannin inhibits the reaction [Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of INSR mRNA]]; xanthoceraside inhibits the reaction [Streptozocin results in decreased expression of INSR protein] streptozocin increases expression of hepatic mRNA |
CTD RGD |
PMID:9243097 PMID:17068109 PMID:18331706 PMID:19705549 PMID:21439094 PMID:23562514 PMID:23927877 PMID:25446853 PMID:25808216 PMID:26286522 PMID:26522834 PMID:29614383 PMID:32805344 PMID:33359794 PMID:36547818 PMID:37566541 PMID:1280238 More...
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RGD:15036814 |
NCBI chr 8:3,200,922...3,329,649
Ensembl chr 8:3,172,061...3,329,617
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G |
Insrr |
insulin receptor-related receptor |
multiple interactions |
EXP |
[Dietary Fats co-treated with Streptozocin] results in decreased expression of INSRR mRNA; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of INSRR mRNA] |
CTD |
PMID:33359794 |
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NCBI chr 3:87,704,215...87,723,408
Ensembl chr 3:87,704,258...87,723,408
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G |
Irak1 |
interleukin-1 receptor-associated kinase 1 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of IRAK1 protein Glyburide inhibits the reaction [Streptozocin results in increased expression of IRAK1 protein]; Tropisetron inhibits the reaction [Streptozocin results in increased expression of IRAK1 protein] |
CTD |
PMID:36504472 |
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NCBI chr X:73,057,520...73,067,527
Ensembl chr X:73,057,520...73,067,524
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G |
Irf1 |
interferon regulatory factor 1 |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of IRF1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr11:53,660,841...53,669,200
Ensembl chr11:53,660,841...53,669,200
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G |
Irf2 |
interferon regulatory factor 2 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of IRF2 mRNA Hirudins inhibits the reaction [Streptozocin results in increased expression of IRF2 mRNA] |
CTD |
PMID:34212273 |
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NCBI chr 8:47,192,751...47,300,493
Ensembl chr 8:47,192,767...47,300,493
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G |
Irs1 |
insulin receptor substrate 1 |
multiple interactions decreases expression decreases phosphorylation |
EXP ISO |
[Dietary Fats co-treated with Streptozocin] results in decreased expression of IRS1 mRNA; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of IRS1 protein; [Streptozocin co-treated with Dietary Fats] affects the phosphorylation of IRS1 protein; [Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of IRS1 protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of IRS1 protein]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of IRS1 mRNA]; Metformin inhibits the reaction [Streptozocin results in decreased expression of IRS1 protein]; Metformin promotes the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of IRS1 protein]; perilla seed oil inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of IRS1 protein]; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] affects the phosphorylation of IRS1 protein] [Dietary Fats co-treated with Streptozocin] results in decreased expression of IRS1 protein; [Streptozocin co-treated with Cadmium] results in decreased expression of IRS1 protein; asiatic acid inhibits the reaction [Streptozocin results in decreased expression of IRS1 protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of IRS1 protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased expression of IRS1 protein]; nerolidol inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of IRS1 protein]; Phosphocreatine inhibits the reaction [Streptozocin results in decreased phosphorylation of IRS1 protein]; Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of IRS1 mRNA]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of IRS1 mRNA]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of IRS1 protein]; Rivastigmine inhibits the reaction [Streptozocin results in decreased expression of IRS1 mRNA]; Wortmannin inhibits the reaction [Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of IRS1 mRNA]] Streptozocin results in decreased expression of IRS1 mRNA; Streptozocin results in decreased expression of IRS1 protein |
CTD |
PMID:23927877 PMID:24923654 PMID:26071184 PMID:26286522 PMID:26522834 PMID:31743741 PMID:32805344 PMID:33359794 PMID:33484791 PMID:34455488 PMID:36169646 More...
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NCBI chr 1:82,210,826...82,269,160
Ensembl chr 1:82,210,822...82,269,137
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G |
Irs2 |
insulin receptor substrate 2 |
multiple interactions decreases expression |
ISO EXP |
[Streptozocin co-treated with Cadmium] results in decreased expression of IRS2 protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of IRS2 protein; asiatic acid inhibits the reaction [Streptozocin results in decreased expression of IRS2 protein]; eupafolin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of IRS2 protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of IRS2 protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased expression of IRS2 protein]; myrtenal inhibits the reaction [Streptozocin results in decreased expression of IRS2 protein]; piperlongumine inhibits the reaction [Streptozocin results in decreased expression of IRS2 protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of IRS2 protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of IRS2 mRNA] Streptozocin results in decreased expression of IRS2 mRNA; Streptozocin results in decreased expression of IRS2 protein [Streptozocin co-treated with bisphenol A] results in decreased expression of IRS2 mRNA; [Streptozocin co-treated with octylphenol] results in decreased expression of IRS2 mRNA |
CTD |
PMID:24923654 PMID:26071184 PMID:26286522 PMID:27417257 PMID:29935216 PMID:33724628 PMID:37566541 More...
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NCBI chr 8:11,034,681...11,058,929
Ensembl chr 8:11,034,681...11,058,458
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G |
Isyna1 |
myo-inositol 1-phosphate synthase A1 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of ISYNA1 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of ISYNA1 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 8:71,047,131...71,049,940
Ensembl chr 8:71,047,023...71,049,940
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G |
Itga3 |
integrin alpha 3 |
multiple interactions decreases expression |
EXP ISO |
notoginsenoside R1 inhibits the reaction [Streptozocin results in decreased expression of ITGA3 mRNA]; notoginsenoside R1 inhibits the reaction [Streptozocin results in decreased expression of ITGA3 protein] Streptozocin results in decreased expression of ITGA3 mRNA; Streptozocin results in decreased expression of ITGA3 protein |
CTD |
PMID:25503068 |
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NCBI chr11:94,935,301...94,967,637
Ensembl chr11:94,935,300...94,967,627
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G |
Itgal |
integrin alpha L |
multiple interactions increases expression |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of ITGAL mRNA; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of ITGAL protein] |
CTD |
PMID:16129698 PMID:25905778 |
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NCBI chr 7:126,895,404...126,934,309
Ensembl chr 7:126,895,432...126,934,310
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G |
Itgam |
integrin alpha M |
multiple interactions increases expression |
ISO |
Ibuprofen inhibits the reaction [Streptozocin results in increased expression of ITGAM mRNA]; Ibuprofen inhibits the reaction [Streptozocin results in increased expression of ITGAM protein]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of ITGAM protein]; Memantine inhibits the reaction [Streptozocin results in increased expression of ITGAM mRNA]; Memantine inhibits the reaction [Streptozocin results in increased expression of ITGAM protein] Streptozocin results in increased expression of ITGAM mRNA; Streptozocin results in increased expression of ITGAM protein |
CTD |
PMID:16129698 PMID:24333387 |
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NCBI chr 7:127,661,812...127,717,663
Ensembl chr 7:127,661,812...127,717,663
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G |
Itgav |
integrin alpha V |
affects expression |
EXP |
Streptozocin affects the expression of ITGAV mRNA |
CTD |
PMID:26073000 |
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NCBI chr 2:83,554,796...83,637,261
Ensembl chr 2:83,554,741...83,637,260
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G |
Itgb1 |
integrin beta 1 (fibronectin receptor beta) |
decreases expression multiple interactions |
ISO EXP |
Streptozocin results in decreased expression of ITGB1 mRNA; Streptozocin results in decreased expression of ITGB1 protein notoginsenoside R1 inhibits the reaction [Streptozocin results in decreased expression of ITGB1 mRNA]; notoginsenoside R1 inhibits the reaction [Streptozocin results in decreased expression of ITGB1 protein] |
CTD |
PMID:25503068 |
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NCBI chr 8:129,412,135...129,460,060
Ensembl chr 8:129,412,135...129,459,681
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G |
Itgb2 |
integrin beta 2 |
multiple interactions increases expression |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of ITGB2 mRNA; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of ITGB2 protein] |
CTD |
PMID:16129698 PMID:25905778 |
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NCBI chr10:77,366,164...77,401,542
Ensembl chr10:77,366,086...77,401,542
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G |
Itpr3 |
inositol 1,4,5-triphosphate receptor 3 |
multiple interactions increases expression |
EXP |
[bisphenol A co-treated with Streptozocin] results in increased expression of ITPR3 mRNA; [octylphenol co-treated with Streptozocin] results in increased expression of ITPR3 mRNA Streptozocin results in increased expression of ITPR3 mRNA |
CTD |
PMID:29935216 |
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NCBI chr17:27,275,976...27,341,197
Ensembl chr17:27,276,278...27,341,197
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G |
Jak2 |
Janus kinase 2 |
multiple interactions increases expression |
ISO |
7-hydroxycoumarin inhibits the reaction [Streptozocin results in increased expression of JAK2 mRNA]; 7-hydroxycoumarin inhibits the reaction [Streptozocin results in increased expression of JAK2 protein]; [Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of JAK2 protein; dapagliflozin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of JAK2 protein] Streptozocin results in increased expression of JAK2 mRNA; Streptozocin results in increased expression of JAK2 protein |
CTD |
PMID:34391751 PMID:36650709 |
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NCBI chr19:29,229,006...29,290,495
Ensembl chr19:29,229,228...29,290,480
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G |
Jun |
jun proto-oncogene |
multiple interactions increases expression |
ISO EXP |
resveratrol inhibits the reaction [Streptozocin results in increased expression of JUN protein] formononetin inhibits the reaction [Streptozocin results in increased expression of JUN mRNA]; formononetin inhibits the reaction [Streptozocin results in increased expression of JUN protein]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of JUN mRNA]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Streptozocin promotes the reaction [JUN protein binds to MMP9 promoter]]; SIRT1 protein inhibits the reaction [Streptozocin promotes the reaction [JUN protein binds to PARP1 protein]]; Streptozocin promotes the reaction [JUN protein binds to MMP9 promoter]; Streptozocin promotes the reaction [JUN protein binds to PARP1 protein] Streptozocin results in increased expression of JUN mRNA; Streptozocin results in increased expression of JUN protein |
CTD |
PMID:26499206 PMID:28478229 PMID:30642005 PMID:35315182 |
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NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459
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G |
Kcnab3 |
potassium voltage-gated channel, shaker-related subfamily, beta member 3 |
multiple interactions |
EXP |
[Dietary Fats co-treated with Streptozocin] results in increased expression of KCNAB3 mRNA; ginsenoside Rh4 affects the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of KCNAB3 mRNA] |
CTD |
PMID:33359794 |
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NCBI chr11:69,217,084...69,223,867
Ensembl chr11:69,217,084...69,223,868
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G |
Kcnh1 |
potassium voltage-gated channel, subfamily H (eag-related), member 1 |
multiple interactions |
EXP |
[Dietary Fats co-treated with Streptozocin] results in increased expression of KCNH1 mRNA; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of KCNH1 mRNA] |
CTD |
PMID:33359794 |
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NCBI chr 1:191,871,759...192,192,467
Ensembl chr 1:191,873,082...192,192,467
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G |
Kcnn2 |
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2 |
increases expression |
EXP |
Streptozocin results in increased expression of KCNN2 protein |
CTD |
PMID:30635400 |
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NCBI chr18:45,401,754...45,818,954
Ensembl chr18:45,401,927...45,818,950
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G |
Kcnn4 |
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 |
increases expression multiple interactions |
ISO EXP |
Streptozocin increases expression of Kcnn4 mRNA and protein in thoracic aorta smooth muscle tissue exendin-4 inhibits the reaction [Streptozocin increases expression of Kcnn4 mRNA and protein in thoracic aorta smooth muscle tissue] streptozocin cotreated with high fat diet increases expression of Kcnn4 protein in aorta |
RGD |
PMID:29167619 PMID:29167619 PMID:35149165 |
RGD:401784495, RGD:401784495, RGD:401784497 |
NCBI chr 7:24,069,750...24,084,635
Ensembl chr 7:24,069,688...24,086,115
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G |
Kcnt1 |
potassium channel, subfamily T, member 1 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of KCNT1 mRNA |
CTD |
PMID:33484791 |
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NCBI chr 2:25,753,807...25,808,285
Ensembl chr 2:25,753,746...25,808,285
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G |
Kdr |
kinase insert domain protein receptor |
multiple interactions increases expression |
ISO EXP |
Simvastatin inhibits the reaction [Streptozocin results in increased expression of KDR mRNA]; Simvastatin inhibits the reaction [Streptozocin results in increased phosphorylation of and results in increased expression of KDR protein]; Streptozocin results in increased phosphorylation of and results in increased expression of KDR protein Streptozocin results in increased expression of KDR mRNA; Streptozocin results in increased expression of KDR protein [Dietary Fats co-treated with Streptozocin] results in increased expression of KDR protein; Rosuvastatin Calcium inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of KDR protein]; sarpogrelate inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of KDR protein] |
CTD |
PMID:15643138 PMID:20821229 PMID:27097221 |
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NCBI chr 5:76,093,487...76,139,880
Ensembl chr 5:76,093,487...76,139,118
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G |
Keap1 |
kelch-like ECH-associated protein 1 |
multiple interactions decreases expression increases expression |
ISO EXP |
[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of KEAP1 mRNA; [Streptozocin co-treated with Niacinamide] results in increased expression of KEAP1 mRNA; [Streptozocin co-treated with Niacinamide] results in increased expression of KEAP1 protein; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of KEAP1 mRNA]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of KEAP1 mRNA]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of KEAP1 protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of KEAP1 mRNA]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of KEAP1 protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of KEAP1 mRNA]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of KEAP1 mRNA]; isoquercitrin inhibits the reaction [Streptozocin results in decreased expression of KEAP1 mRNA]; Metformin inhibits the reaction [Streptozocin results in increased expression of KEAP1 mRNA]; Metformin inhibits the reaction [Streptozocin results in increased expression of KEAP1 protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of KEAP1 mRNA]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of KEAP1 protein]; rhapontin inhibits the reaction [Streptozocin results in increased expression of KEAP1 mRNA]; rhapontin inhibits the reaction [Streptozocin results in increased expression of KEAP1 protein] Streptozocin results in increased expression of KEAP1 mRNA; Streptozocin results in increased expression of KEAP1 protein 2,5-dihydroxybenzoic acid promotes the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of KEAP1 mRNA]; [Streptozocin co-treated with Dietary Fats] results in increased expression of KEAP1 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of KEAP1 protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of KEAP1 mRNA; Acrylamide inhibits the reaction [Streptozocin results in increased expression of KEAP1 mRNA]; Metformin promotes the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of KEAP1 mRNA]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of KEAP1 mRNA]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of KEAP1 protein] |
CTD |
PMID:21439372 PMID:30817903 PMID:32662907 PMID:33639173 PMID:34610774 PMID:34896238 PMID:36510688 PMID:37120126 More...
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NCBI chr 9:21,141,026...21,150,628
Ensembl chr 9:21,141,026...21,150,657
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G |
Kel |
Kell blood group |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of KEL mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of KEL mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 6:41,663,263...41,681,268
Ensembl chr 6:41,663,264...41,681,273
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G |
Kl |
klotho |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of KL rosiglitazone inhibits the reaction [Streptozocin results in decreased expression of KL] |
CTD |
PMID:24136780 |
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NCBI chr 5:150,876,072...150,917,282
Ensembl chr 5:150,876,072...150,917,282
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G |
Klf15 |
Kruppel-like transcription factor 15 |
multiple interactions |
EXP |
[Dietary Fats co-treated with Streptozocin] promotes the reaction [KLF15 gene mutant form results in increased expression of CCN2 protein]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of KLF15 protein; CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of KLF15 protein]; KLF15 gene mutant form inhibits the reaction [CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CCN2 protein]]; KLF15 gene mutant form inhibits the reaction [CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FN1 protein]]; KLF15 gene mutant form inhibits the reaction [CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein]]; KLF15 gene mutant form promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CCN2 protein]; KLF15 gene mutant form promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FN1 protein]; KLF15 gene mutant form promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein]; KLF15 gene mutant form results in increased susceptibility to [Dietary Fats co-treated with Streptozocin] |
CTD |
PMID:34310909 |
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NCBI chr 6:90,437,785...90,468,785
Ensembl chr 6:90,439,558...90,452,220
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G |
Klf4 |
Kruppel-like transcription factor 4 (gut) |
multiple interactions |
ISO |
[Resveratrol co-treated with Streptozocin] results in increased expression of KLF4 mRNA; [Streptozocin co-treated with Niacinamide] promotes the reaction [Dronabinol results in increased expression of KLF4 mRNA] |
CTD |
PMID:25905778 PMID:31081965 |
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NCBI chr 4:55,527,137...55,536,984
Ensembl chr 4:55,527,143...55,532,466
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G |
Klk1 |
kallikrein 1 |
multiple interactions increases expression |
ISO EXP |
KLK1 protein inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of ITGAL protein]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of ITGAM protein]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of ITGB2 protein]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of TNF protein]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of VCAM1 protein] Streptozocin results in increased expression of KLK1 mRNA |
CTD |
PMID:16129698 PMID:19516248 |
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NCBI chr 7:43,874,784...43,879,046
Ensembl chr 7:43,874,784...43,879,042
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G |
Klk1b4 |
kallikrein 1-related pepidase b4 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of KLK1B4 mRNA |
CTD |
PMID:29127188 |
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NCBI chr 7:43,856,857...43,861,178
Ensembl chr 7:43,856,859...43,861,178
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G |
Kng1 |
kininogen 1 |
multiple interactions increases response to substance |
ISO |
Streptozocin promotes the reaction [KNG1 protein modified form results in increased secretion of Dinoprostone]; Streptozocin promotes the reaction [KNG1 protein modified form results in increased secretion of TAC1 protein modified form] Streptozocin results in increased susceptibility to KNG1 protein modified form |
CTD |
PMID:20832942 |
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NCBI chr16:22,876,970...22,900,828
Ensembl chr16:22,876,615...22,900,828
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G |
Krt19 |
keratin 19 |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of KRT19 mRNA |
CTD |
PMID:25905778 |
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NCBI chr11:100,031,636...100,036,752
Ensembl chr11:100,031,636...100,039,491
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G |
Kynu |
kynureninase |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in decreased expression of KYNU mRNA |
CTD |
PMID:25905778 |
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NCBI chr 2:43,445,270...43,572,734
Ensembl chr 2:43,445,341...43,572,734
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G |
Lama1 |
laminin, alpha 1 |
multiple interactions |
EXP |
[Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of LAMA1 protein]; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of LAMA1 protein |
CTD |
PMID:38282657 |
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NCBI chr17:68,004,129...68,129,640
Ensembl chr17:68,004,254...68,129,642
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G |
Lamp1 |
lysosomal-associated membrane protein 1 |
multiple interactions |
ISO |
[[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in decreased expression of LAMP1 mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of LAMP1 mRNA; [Carbamazepine affects the susceptibility to [Dietary Fats co-treated with Streptozocin]] which results in decreased expression of LAMP1 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of LAMP1 mRNA |
CTD |
PMID:35786680 |
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NCBI chr 8:13,209,161...13,225,338
Ensembl chr 8:13,209,161...13,225,338
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G |
Lamp2 |
lysosomal-associated membrane protein 2 |
multiple interactions |
ISO |
[[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in decreased expression of LAMP2 mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of LAMP2 mRNA; [Carbamazepine affects the susceptibility to [Dietary Fats co-treated with Streptozocin]] which results in decreased expression of LAMP2 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of LAMP2 mRNA |
CTD |
PMID:35786680 |
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NCBI chr X:37,488,524...37,545,337
Ensembl chr X:37,490,234...37,545,331
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G |
Lap3 |
leucine aminopeptidase 3 |
affects expression |
EXP |
Streptozocin affects the expression of LAP3 mRNA |
CTD |
PMID:18583417 |
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NCBI chr 5:45,650,716...45,670,033
Ensembl chr 5:45,650,716...45,670,033
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G |
Laptm5 |
lysosomal-associated protein transmembrane 5 |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of LAPTM5 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 4:130,640,627...130,663,459
Ensembl chr 4:130,640,436...130,663,452
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G |
Lcat |
lecithin cholesterol acyltransferase |
multiple interactions |
ISO EXP |
[Streptozocin co-treated with Cadmium] results in decreased activity of LCAT protein; [Streptozocin co-treated with Niacinamide] results in decreased activity of LCAT protein; [tetrahydrocurcumin co-treated with Chlorogenic Acid] results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in decreased activity of LCAT protein]; Chlorogenic Acid results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in decreased activity of LCAT protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased activity of LCAT protein]; tetrahydrocurcumin results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in decreased activity of LCAT protein] [Streptozocin co-treated with Dietary Fats] results in decreased expression of LCAT protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of LCAT protein] |
CTD |
PMID:20696151 PMID:25240712 PMID:33484791 |
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NCBI chr 8:106,666,183...106,670,034
Ensembl chr 8:106,666,183...106,670,014
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G |
Lcn2 |
lipocalin 2 |
multiple interactions |
ISO EXP |
[Resveratrol co-treated with Streptozocin] results in increased expression of LCN2 mRNA; [Streptozocin co-treated with Fructose] results in increased expression of LCN2 protein; [Streptozocin co-treated with iomeprol] results in increased expression of LCN2 protein; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of LCN2 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of LCN2 protein]; palmidrol analog inhibits the reaction [[Streptozocin co-treated with iomeprol] results in increased expression of LCN2 protein] [Streptozocin co-treated with Dietary Fats] results in increased expression of LCN2 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of LCN2 mRNA] |
CTD |
PMID:25905778 PMID:26474837 PMID:30551545 PMID:33484791 |
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NCBI chr 2:32,274,649...32,277,751
Ensembl chr 2:32,274,645...32,278,264
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G |
Ldhb |
lactate dehydrogenase B |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of LDHB protein Trientine inhibits the reaction [Streptozocin results in increased expression of LDHB protein] |
CTD |
PMID:19634143 PMID:21136691 |
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NCBI chr 6:142,435,975...142,453,683
Ensembl chr 6:142,435,975...142,453,683
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G |
Ldlr |
low density lipoprotein receptor |
multiple interactions decreases expression |
EXP |
[Dietary Fats co-treated with Streptozocin] results in decreased expression of LDLR mRNA; Acrylamide inhibits the reaction [Streptozocin results in decreased expression of LDLR mRNA]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of LDLR mRNA] |
CTD |
PMID:33359794 PMID:34896238 |
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NCBI chr 9:21,634,872...21,661,215
Ensembl chr 9:21,634,779...21,661,215
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G |
Lep |
leptin |
multiple interactions |
ISO EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of LEP protein; morin analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of LEP protein]; Zinc Compounds inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of LEP protein] [Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of LEP protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of LEP protein; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of LEP protein]; Omaveloxolone analog promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of LEP protein] |
CTD |
PMID:24854284 PMID:29988851 PMID:32410268 |
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NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876
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G |
Lepr |
leptin receptor |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of LEPR mRNA |
CTD |
PMID:29127188 |
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NCBI chr 4:101,574,393...101,676,375
Ensembl chr 4:101,574,601...101,672,549
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G |
Lgals3 |
lectin, galactose binding, soluble 3 |
multiple interactions increases expression |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of LGALS3 mRNA; vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of LGALS3 mRNA] |
CTD |
PMID:16684804 PMID:25905778 |
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NCBI chr14:47,611,317...47,623,624
Ensembl chr14:47,605,208...47,623,617
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G |
Lhb |
luteinizing hormone beta |
decreases expression multiple interactions |
ISO EXP |
Streptozocin results in decreased expression of LHB protein Sildenafil Citrate inhibits the reaction [Streptozocin results in decreased expression of LHB protein]; vitexin inhibits the reaction [Streptozocin results in decreased expression of LHB protein] [Streptozocin co-treated with Fructose] results in decreased expression of LHB protein; Acetates inhibits the reaction [[Streptozocin co-treated with Fructose] results in decreased expression of LHB protein]; carvacrol affects the reaction [Streptozocin results in decreased expression of LHB protein] |
CTD |
PMID:19931367 PMID:30365938 PMID:32153207 PMID:34656705 |
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NCBI chr 7:45,070,370...45,071,278
Ensembl chr 7:45,070,244...45,071,321
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G |
Lhcgr |
luteinizing hormone/choriogonadotropin receptor |
multiple interactions decreases expression |
ISO |
carvacrol affects the reaction [Streptozocin results in decreased expression of LHCGR mRNA]; carvacrol affects the reaction [Streptozocin results in decreased expression of LHCGR protein] Streptozocin results in decreased expression of LHCGR mRNA; Streptozocin results in decreased expression of LHCGR protein |
CTD |
PMID:32153207 |
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NCBI chr17:89,023,812...89,099,487
Ensembl chr17:89,023,909...89,099,418
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G |
Limk2 |
LIM domain kinase 2 |
multiple interactions increases phosphorylation |
ISO |
fasudil inhibits the reaction [Streptozocin results in increased phosphorylation of LIMK2 protein] |
CTD |
PMID:22062134 |
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NCBI chr11:3,293,297...3,359,238
Ensembl chr11:3,294,256...3,359,189
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G |
Lipc |
lipase, hepatic |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of LIPC protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of LIPC protein] |
CTD |
PMID:33484791 |
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NCBI chr 9:70,705,410...70,859,503
Ensembl chr 9:70,705,410...70,859,508
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G |
Lipe |
lipase, hormone sensitive |
multiple interactions increases expression |
ISO EXP |
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of LIPE mRNA] [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of HSL mRNA |
CTD |
PMID:16684804 PMID:39047806 |
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NCBI chr 7:25,078,952...25,097,911
Ensembl chr 7:25,078,952...25,098,135
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G |
Litaf |
LPS-induced TN factor |
decreases expression |
ISO |
Streptozocin results in decreased expression of LITAF mRNA |
CTD |
PMID:25905778 |
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NCBI chr16:10,777,137...10,810,985
Ensembl chr16:10,777,139...10,884,021
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G |
Lncpint |
long non-protein coding RNA, Trp53 induced transcript |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of LNCPINT mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of LNCPINT mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 6:31,070,498...31,195,409
Ensembl chr 6:31,059,500...31,197,607
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G |
Lpin2 |
lipin 2 |
increases expression |
ISO |
Streptozocin results in increased expression of LPIN2 mRNA |
CTD |
PMID:25905778 |
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NCBI chr17:71,490,527...71,556,813
Ensembl chr17:71,489,555...71,556,812
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G |
Lpl |
lipoprotein lipase |
multiple interactions |
ISO EXP |
[Streptozocin co-treated with Cadmium] results in decreased activity of LPL protein; [Streptozocin co-treated with Niacinamide] results in decreased activity of LPL protein; [tetrahydrocurcumin co-treated with Chlorogenic Acid] results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in decreased activity of LPL protein]; Chlorogenic Acid results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in decreased activity of LPL protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased activity of LPL protein]; tetrahydrocurcumin results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in decreased activity of LPL protein] [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of LPL mRNA]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of LPL mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of LPL mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of LPL mRNA; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of LPL mRNA] |
CTD |
PMID:20696151 PMID:25240712 PMID:25446853 PMID:29127188 PMID:39047806 |
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NCBI chr 8:69,333,207...69,359,584
Ensembl chr 8:69,333,143...69,360,100
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G |
Lrp5 |
low density lipoprotein receptor-related protein 5 |
affects expression |
EXP |
Streptozocin affects the expression of LRP5 mRNA |
CTD |
PMID:18583417 |
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NCBI chr19:3,634,825...3,736,574
Ensembl chr19:3,634,828...3,736,564
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G |
Lst1 |
leukocyte specific transcript 1 |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of LST1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr17:35,404,071...35,407,416
Ensembl chr17:35,404,071...35,407,415
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G |
Ly6c1 |
lymphocyte antigen 6 family member C1 |
multiple interactions |
EXP |
[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of LY6C1 mRNA; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of LY6C1 mRNA] |
CTD |
PMID:39047806 |
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NCBI chr15:74,915,867...74,920,690
Ensembl chr15:74,915,867...74,920,679
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G |
Ly6g |
lymphocyte antigen 6 family member G |
multiple interactions |
EXP |
[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of LY6G mRNA; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of LY6G mRNA] |
CTD |
PMID:39047806 |
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NCBI chr15:75,027,110...75,030,977
Ensembl chr15:75,027,089...75,030,975
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G |
Lyz2 |
lysozyme 2 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of LYZ mRNA vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of LYZ mRNA] |
CTD |
PMID:16684804 |
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NCBI chr10:117,113,446...117,118,177
Ensembl chr10:117,113,236...117,118,226
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G |
Mafa |
MAF bZIP transcription factor A |
multiple interactions decreases expression |
EXP |
[Dietary Fats co-treated with Streptozocin] results in decreased expression of MAFA mRNA; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of MAFA mRNA]; octylphenol inhibits the reaction [Streptozocin results in decreased expression of MAFA mRNA] |
CTD |
PMID:24781736 PMID:29935216 PMID:33359794 |
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NCBI chr15:75,617,350...75,620,170
Ensembl chr15:75,617,339...75,620,077
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G |
Mak |
male germ cell-associated kinase |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of MAK mRNA |
CTD |
PMID:33484791 |
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NCBI chr13:41,178,483...41,233,182
Ensembl chr13:41,178,484...41,233,182
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G |
Map1lc3a |
microtubule-associated protein 1 light chain 3 alpha |
multiple interactions |
ISO |
[Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in increased expression of MAP1LC3A protein |
CTD |
PMID:35786680 |
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NCBI chr 2:155,118,284...155,119,993
Ensembl chr 2:155,118,217...155,119,993
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G |
Map1lc3b |
microtubule-associated protein 1 light chain 3 beta |
multiple interactions increases lipidation decreases expression increases expression |
ISO |
[[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of MAP1LC3B mRNA; [Zinc co-treated with Selenium] inhibits the reaction [Streptozocin results in increased expression of MAP1LC3B protein]; dapagliflozin inhibits the reaction [Streptozocin results in decreased expression of MAP1LC3B mRNA] Streptozocin results in increased lipidation of MAP1LC3B protein |
CTD |
PMID:32233808 PMID:35786680 PMID:37352119 PMID:38706688 |
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NCBI chr 8:122,317,177...122,325,499
Ensembl chr 8:122,317,100...122,325,499
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G |
Map2 |
microtubule-associated protein 2 |
multiple interactions decreases expression |
EXP ISO |
Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of MAP2 protein]; Physostigmine inhibits the reaction [Streptozocin results in decreased expression of MAP2 protein] Vitamin B 12 inhibits the reaction [Streptozocin results in decreased expression of MAP2 protein] |
CTD |
PMID:28499986 PMID:38049026 |
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NCBI chr 1:66,214,337...66,481,742
Ensembl chr 1:66,214,432...66,481,742
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G |
Map2k4 |
mitogen-activated protein kinase kinase 4 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAP2K4 protein; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAP2K4 protein] |
CTD |
PMID:26522834 |
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NCBI chr11:65,579,070...65,679,185
Ensembl chr11:65,579,069...65,679,123
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G |
Map2k6 |
mitogen-activated protein kinase kinase 6 |
increases expression |
ISO |
Streptozocin results in increased expression of MAP2K6 mRNA |
CTD |
PMID:25905778 |
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NCBI chr11:110,289,928...110,416,348
Ensembl chr11:110,289,948...110,416,348
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G |
Map3k5 |
mitogen-activated protein kinase kinase kinase 5 |
multiple interactions increases expression |
EXP ISO |
[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAP3K5 protein; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAP3K5 protein]; Streptozocin promotes the reaction [MAP3K5 protein results in increased expression of SERPINE1 protein] resveratrol inhibits the reaction [Streptozocin results in increased expression of MAP3K5 protein] |
CTD |
PMID:16731828 PMID:26499206 PMID:26522834 |
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NCBI chr10:19,809,847...20,018,496
Ensembl chr10:19,810,218...20,018,499
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G |
Mapk1 |
mitogen-activated protein kinase 1 |
multiple interactions increases activity increases expression increases phosphorylation decreases phosphorylation |
ISO EXP |
1,3-dimethoxy-5-methyl-2-(3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl)benzene inhibits the reaction [4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in decreased phosphorylation of MAPK1 protein]]; 4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in decreased phosphorylation of MAPK1 protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein]; baicalin inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein]; Botulinum Toxins, Type A inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein]; capsazepine inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein]; Donepezil inhibits the reaction [Streptozocin results in decreased phosphorylation of MAPK1 protein]; Memantine inhibits the reaction [Streptozocin results in decreased phosphorylation of MAPK1 protein]; Metformin inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of MAPK1 mRNA]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of MAPK1 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein]; RN 1734 inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein]; Streptozocin results in increased phosphorylation of and results in increased activity of MAPK1 protein; U 0126 inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein]; xanthoceraside inhibits the reaction [Streptozocin results in decreased phosphorylation of MAPK1 protein] Streptozocin results in increased activity of MAPK1 protein Streptozocin results in increased expression of MAPK1 mRNA; Streptozocin results in increased expression of MAPK1 protein Streptozocin inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK1 protein] 3-((6-(2-methoxyphenyl)pyrimidin-4-yl)amino)phenyl)methane sulfonamide inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein]; [Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of and results in decreased phosphorylation of MAPK1 protein; [Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased phosphorylation of MAPK1 protein; [Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAPK1 protein; arachidonyl-2-chloroethylamide promotes the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein]; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAPK1 protein]; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of and results in decreased phosphorylation of MAPK1 protein]; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased phosphorylation of MAPK1 protein]; Streptozocin promotes the reaction [NTN1 protein results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:12642375 PMID:17063547 PMID:19002579 PMID:19133311 PMID:19682444 PMID:20053369 PMID:20474069 PMID:21300041 PMID:23562514 PMID:25541468 PMID:29059224 PMID:29274332 PMID:30583000 PMID:30607903 PMID:32303808 PMID:33484791 PMID:33631230 PMID:33639173 PMID:34414639 More...
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NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
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G |
Mapk10 |
mitogen-activated protein kinase 10 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of MAPK10 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of MAPK10 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 5:103,056,413...103,359,200
Ensembl chr 5:103,055,814...103,359,200
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G |
Mapk11 |
mitogen-activated protein kinase 11 |
multiple interactions |
EXP |
[Dietary Fats co-treated with Streptozocin] results in increased expression of MAPK11 protein |
CTD |
PMID:34310909 |
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NCBI chr15:89,026,685...89,033,809
Ensembl chr15:89,026,689...89,033,831
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Mapk14 |
mitogen-activated protein kinase 14 |
increases phosphorylation multiple interactions |
EXP ISO |
Streptozocin results in increased phosphorylation of MAPK14 protein Atorvastatin inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK14 protein] |
CTD |
PMID:15232685 PMID:17589825 |
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NCBI chr17:28,910,316...28,967,379
Ensembl chr17:28,910,303...28,967,380
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Mapk3 |
mitogen-activated protein kinase 3 |
increases activity increases expression multiple interactions increases phosphorylation decreases phosphorylation |
ISO EXP |
Streptozocin results in increased activity of MAPK3 protein Streptozocin results in increased expression of MAPK3 mRNA 1,3-dimethoxy-5-methyl-2-(3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl)benzene inhibits the reaction [4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in decreased phosphorylation of MAPK3 protein]]; 4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in decreased phosphorylation of MAPK3 protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased phosphorylation of and results in increased activity of MAPK3 protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein]; baicalin inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein]; Botulinum Toxins, Type A inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein]; capsazepine inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein]; Donepezil inhibits the reaction [Streptozocin results in decreased phosphorylation of MAPK3 protein]; Memantine inhibits the reaction [Streptozocin results in decreased phosphorylation of MAPK3 protein]; Metformin inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein]; RN 1734 inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein]; Streptozocin results in increased phosphorylation of and results in increased activity of MAPK3 protein; U 0126 inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein]; xanthoceraside inhibits the reaction [Streptozocin results in decreased phosphorylation of MAPK3 protein] Streptozocin inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK3 protein] 3-((6-(2-methoxyphenyl)pyrimidin-4-yl)amino)phenyl)methane sulfonamide inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein]; [Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased phosphorylation of MAPK3 protein; [Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAPK3 protein; arachidonyl-2-chloroethylamide promotes the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein]; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAPK3 protein]; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased phosphorylation of MAPK3 protein]; Streptozocin promotes the reaction [NTN1 protein results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:12642375 PMID:19002579 PMID:19133311 PMID:19682444 PMID:20053369 PMID:20474069 PMID:21300041 PMID:23562514 PMID:25541468 PMID:29059224 PMID:29274332 PMID:30583000 PMID:30607903 PMID:32303808 PMID:33484791 PMID:33631230 PMID:33639173 PMID:34414639 More...
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NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
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Mapk8 |
mitogen-activated protein kinase 8 |
multiple interactions increases phosphorylation |
ISO EXP |
Streptozocin inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK8 protein] [Carnosine co-treated with asiatic acid] inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein]; [Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAPK8 protein; asiatic acid inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein]; Carnosine inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein]; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAPK8 protein]; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAPK8 protein] [Resveratrol co-treated with Ramipril] inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein]; Ramipril inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein] |
CTD |
PMID:25541468 PMID:26522834 PMID:30802477 PMID:31062909 PMID:33484791 |
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NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115
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Mapk9 |
mitogen-activated protein kinase 9 |
multiple interactions increases expression |
ISO EXP |
chromium mesoporphyrin inhibits the reaction [Hemin inhibits the reaction [Streptozocin results in increased expression of MAPK9 mRNA]]; Hemin inhibits the reaction [Streptozocin results in increased expression of MAPK9 mRNA] Streptozocin inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK9 protein] [Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAPK9 protein; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAPK9 protein] |
CTD |
PMID:19190261 PMID:25541468 PMID:26522834 |
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NCBI chr11:49,737,558...49,777,248
Ensembl chr11:49,737,578...49,777,248
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Mapkapk2 |
MAP kinase-activated protein kinase 2 |
multiple interactions increases expression |
EXP |
telmisartan inhibits the reaction [Streptozocin results in increased expression of MAPKAPK2 protein modified form] |
CTD |
PMID:21381899 |
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NCBI chr 1:130,981,437...131,025,580
Ensembl chr 1:130,981,437...131,025,563
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Mapt |
microtubule-associated protein tau |
increases phosphorylation multiple interactions increases expression |
EXP ISO |
Streptozocin results in increased phosphorylation of MAPT protein 5-Methoxypsoralen inhibits the reaction [Streptozocin results in increased expression of MAPT protein modified form]; Folic Acid inhibits the reaction [Streptozocin results in increased phosphorylation of MAPT protein]; SOD2 protein inhibits the reaction [Streptozocin results in increased phosphorylation of MAPT protein]; Tadalafil inhibits the reaction [Streptozocin results in increased expression of MAPT protein modified form] Melatonin inhibits the reaction [Streptozocin results in increased phosphorylation of MAPT protein]; Melatonin metabolite inhibits the reaction [Streptozocin results in increased phosphorylation of MAPT protein]; N-acetyl-N-formyl-5-methoxykynurenamine inhibits the reaction [Streptozocin results in increased phosphorylation of MAPT protein] |
CTD |
PMID:20976160 PMID:28422052 PMID:31833155 PMID:34428446 |
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NCBI chr11:104,120,235...104,222,916
Ensembl chr11:104,122,216...104,222,916
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Mas1 |
MAS1 oncogene |
decreases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of MAS1 protein CEBPB protein inhibits the reaction [Streptozocin results in decreased expression of MAS1 protein]; Telmisartan inhibits the reaction [Streptozocin results in decreased expression of MAS1 protein] |
CTD |
PMID:21381899 PMID:29266779 |
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NCBI chr17:13,056,981...13,087,037
Ensembl chr17:13,059,966...13,087,030
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Mat1a |
methionine adenosyltransferase 1A |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] affects the expression of MAT1A mRNA |
CTD |
PMID:29127188 |
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NCBI chr14:40,826,969...40,846,385
Ensembl chr14:40,826,992...40,846,369
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Mat2a |
methionine adenosyltransferase 2A |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of MAT2A mRNA |
CTD |
PMID:29127188 |
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NCBI chr 6:72,409,779...72,416,539
Ensembl chr 6:72,409,782...72,416,541
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Mbp |
myelin basic protein |
multiple interactions decreases expression |
ISO |
20-alpha-Dihydroprogesterone inhibits the reaction [Streptozocin results in decreased expression of MBP mRNA]; Progesterone inhibits the reaction [Streptozocin results in decreased expression of MBP mRNA]; Vitamin B 12 inhibits the reaction [Streptozocin results in decreased expression of MBP protein] Streptozocin results in decreased expression of MBP mRNA; Streptozocin results in decreased expression of MBP protein |
CTD |
PMID:20349157 PMID:38049026 |
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NCBI chr18:82,492,883...82,603,762
Ensembl chr18:82,493,271...82,603,762
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Mcemp1 |
mast cell expressed membrane protein 1 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of MCEMP1 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of MCEMP1 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 8:3,715,754...3,718,916
Ensembl chr 8:3,715,754...3,719,259
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Mdh1 |
malate dehydrogenase 1, NAD (soluble) |
multiple interactions increases expression |
ISO |
Trientine inhibits the reaction [Streptozocin results in increased expression of MDH1 protein] |
CTD |
PMID:21136691 |
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NCBI chr11:21,506,692...21,521,934
Ensembl chr11:21,506,692...21,522,367
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Mdh2 |
malate dehydrogenase 2, NAD (mitochondrial) |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of MDH2 protein Trientine inhibits the reaction [Streptozocin results in decreased expression of MDH2 protein] |
CTD |
PMID:19634143 |
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NCBI chr 5:135,807,503...135,819,240
Ensembl chr 5:135,807,334...135,819,252
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Mecr |
mitochondrial trans-2-enoyl-CoA reductase |
increases expression |
ISO |
Streptozocin results in increased expression of MECR mRNA |
CTD |
PMID:25905778 |
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NCBI chr 4:131,570,755...131,595,097
Ensembl chr 4:131,570,781...131,595,097
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Mef2c |
myocyte enhancer factor 2C |
decreases expression multiple interactions |
EXP ISO |
Streptozocin results in decreased expression of MEF2C mRNA SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of MEF2C mRNA] |
CTD |
PMID:27629361 |
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NCBI chr13:83,652,136...83,815,197
Ensembl chr13:83,652,153...83,815,199
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Mefv |
Mediterranean fever |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of MEFV mRNA |
CTD |
PMID:33484791 |
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NCBI chr16:3,524,838...3,536,073
Ensembl chr16:3,525,082...3,535,961
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Mep1a |
meprin 1 alpha |
multiple interactions |
ISO |
Streptozocin results in decreased activity of and results in decreased expression of MEP1A protein |
CTD |
PMID:15942051 |
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NCBI chr17:43,785,215...43,815,034
Ensembl chr17:43,785,215...43,813,703
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G |
Mff |
mitochondrial fission factor |
multiple interactions |
EXP |
[Dietary Fats co-treated with Streptozocin] results in increased expression of MFF mRNA |
CTD |
PMID:33812996 |
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NCBI chr 1:82,702,599...82,730,111
Ensembl chr 1:82,702,611...82,730,115
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Mfn2 |
mitofusin 2 |
multiple interactions decreases expression |
ISO EXP |
ferulic acid inhibits the reaction [Streptozocin results in decreased expression of MFN2 protein]; MFN2 protein mutant form inhibits the reaction [Streptozocin promotes the reaction [TFAP2A protein binds to COL4A1 promoter]]; MFN2 protein mutant form inhibits the reaction [Streptozocin results in increased expression of COL4A1 mRNA] [Dietary Fats co-treated with Streptozocin] results in decreased expression of MFN2 mRNA; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of MFN2 mRNA] |
CTD |
PMID:27997345 PMID:31029786 PMID:33812996 |
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NCBI chr 4:147,958,043...147,989,527
Ensembl chr 4:147,958,056...147,989,161
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Mgll |
monoglyceride lipase |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in decreased expression of MGLL mRNA |
CTD |
PMID:25905778 |
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NCBI chr 6:88,701,397...88,805,342
Ensembl chr 6:88,701,394...88,805,342
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Mgmt |
O-6-methylguanine-DNA methyltransferase |
decreases response to substance |
ISO |
MGMT protein results in decreased susceptibility to Streptozocin |
CTD |
PMID:16039682 |
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NCBI chr 7:136,496,315...136,732,001
Ensembl chr 7:136,496,343...136,731,995
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G |
Mgst2 |
microsomal glutathione S-transferase 2 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of MGST2 mRNA |
CTD |
PMID:29127188 |
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NCBI chr 3:51,544,179...51,590,096
Ensembl chr 3:51,567,781...51,590,098
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G |
Micu1 |
mitochondrial calcium uptake 1 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of MICU1 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of MICU1 protein; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of MICU1 mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of MICU1 protein]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of MICU1 mRNA]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of MICU1 protein] |
CTD |
PMID:37337224 |
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NCBI chr10:59,538,385...59,699,956
Ensembl chr10:59,538,299...59,699,954
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Mir100 |
microRNA 100 |
decreases expression |
EXP |
Streptozocin results in decreased expression of MIR100 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 9:41,442,721...41,442,800
Ensembl chr 9:41,442,721...41,442,800
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G |
Mir101b |
microRNA 101b |
increases expression |
EXP |
Streptozocin results in increased expression of MIR101B mRNA |
CTD |
PMID:27629361 |
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NCBI chr19:29,112,679...29,112,775
Ensembl chr19:29,112,679...29,112,775
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G |
Mir106a |
microRNA 106a |
increases expression |
EXP |
Streptozocin results in increased expression of MIR106A mRNA |
CTD |
PMID:27629361 |
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NCBI chr X:51,831,380...51,831,444
Ensembl chr X:51,831,380...51,831,444
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G |
Mir10a |
microRNA 10a |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of MIR10A mRNA; HDAC3 protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of MIR10A mRNA]; MIR10A mRNA affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CREB1 protein] |
CTD |
PMID:27292126 |
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NCBI chr11:96,207,991...96,208,100
Ensembl chr11:96,207,991...96,208,100
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Mir1188 |
microRNA 1188 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR1188 mRNA |
CTD |
PMID:27629361 |
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NCBI chr12:109,578,256...109,578,375
Ensembl chr12:109,578,256...109,578,375
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G |
Mir1190 |
microRNA 1190 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR1190 mRNA |
CTD |
PMID:27629361 |
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NCBI chr12:100,987,932...100,988,027
Ensembl chr12:100,987,932...100,988,027
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G |
Mir1251 |
microRNA 1251 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR1251 mRNA |
CTD |
PMID:27629361 |
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NCBI chr10:91,973,002...91,973,085
Ensembl chr10:91,973,002...91,973,085
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Mir125b-1 |
microRNA 125b-1 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR125B-1 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 9:41,493,222...41,493,298
Ensembl chr 9:41,493,222...41,493,298
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G |
Mir128-1 |
microRNA 128-1 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR128-1 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 1:128,130,098...128,130,167
Ensembl chr 1:128,130,098...128,130,167
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G |
Mir1298 |
microRNA 1298 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR1298 mRNA |
CTD |
PMID:27629361 |
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NCBI chr X:145,847,901...145,847,998
Ensembl chr X:145,847,901...145,847,998
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G |
Mir1306 |
microRNA 1306 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR1306 mRNA |
CTD |
PMID:27629361 |
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NCBI chr16:18,102,103...18,102,181
Ensembl chr16:18,102,103...18,102,181
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G |
Mir132 |
microRNA 132 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR132 mRNA |
CTD |
PMID:27629361 |
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NCBI chr11:75,064,508...75,064,573
Ensembl chr11:75,064,508...75,064,573
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G |
Mir135a-2 |
microRNA 135a-2 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR135A-2 mRNA |
CTD |
PMID:27629361 |
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NCBI chr10:91,907,948...91,908,047
Ensembl chr10:91,907,948...91,908,047
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Mir135b |
microRNA 135b |
increases expression |
EXP |
Streptozocin results in increased expression of MIR135B mRNA |
CTD |
PMID:27629361 |
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NCBI chr 1:132,125,826...132,125,922
Ensembl chr 1:132,125,826...132,125,922
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Mir140 |
microRNA 140 |
multiple interactions increases expression |
ISO EXP |
[Antagomirs results in decreased expression of MIR140 mRNA] inhibits the reaction [Streptozocin results in decreased expression of SNX12 protein] streptozocin increases expression of Mir140 RNA in heart |
CTD RGD |
PMID:32062618 PMID:36044268 |
RGD:156430337 |
NCBI chr 8:108,277,876...108,277,945
Ensembl chr 8:108,277,876...108,277,945
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G |
Mir142 |
microRNA 142 |
increases expression multiple interactions |
EXP ISO |
Streptozocin results in increased expression of MIR142 mRNA SOD1 protein inhibits the reaction [Streptozocin results in increased expression of MIR142 mRNA] |
CTD |
PMID:27629361 |
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NCBI chr11:87,647,690...87,647,753
Ensembl chr11:87,647,690...87,647,753
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G |
Mir144 |
microRNA 144 |
increases expression multiple interactions |
EXP ISO |
Streptozocin results in increased expression of MIR144 mRNA SOD1 protein inhibits the reaction [Streptozocin results in increased expression of MIR144 mRNA] |
CTD |
PMID:27629361 |
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NCBI chr11:77,963,831...77,963,896
Ensembl chr11:77,963,831...77,963,896
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G |
Mir146 |
microRNA 146 |
multiple interactions increases expression |
ISO |
Glyburide inhibits the reaction [Streptozocin results in increased expression of MIR146A mRNA]; Tropisetron inhibits the reaction [Streptozocin results in increased expression of MIR146A mRNA] |
CTD |
PMID:36504472 |
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NCBI chr11:43,265,224...43,265,288
Ensembl chr11:43,265,224...43,265,288
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Mir146b |
microRNA 146b |
increases expression |
EXP |
Streptozocin results in increased expression of MIR146B mRNA |
CTD |
PMID:27629361 |
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NCBI chr19:46,331,201...46,331,309
Ensembl chr19:46,331,201...46,331,309
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G |
Mir152 |
microRNA 152 |
multiple interactions |
ISO |
[Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in increased expression of MIR152 mRNA]; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in increased expression of MIR152 mRNA]] |
CTD |
PMID:36547818 |
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NCBI chr11:96,741,219...96,741,291
Ensembl chr11:96,741,219...96,741,291
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Mir155 |
microRNA 155 |
decreases expression |
EXP |
Streptozocin results in decreased expression of MIR155 mRNA |
CTD |
PMID:27629361 |
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NCBI chr16:84,511,028...84,511,092
Ensembl chr16:84,511,028...84,511,092
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G |
Mir18 |
microRNA 18 |
decreases expression |
EXP |
Streptozocin results in decreased expression of MIR18 mRNA |
CTD |
PMID:27629361 |
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NCBI chr14:115,281,283...115,281,378
Ensembl chr14:115,281,283...115,281,378
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Mir184 |
microRNA 184 |
decreases expression |
EXP |
Streptozocin results in decreased expression of MIR184 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 9:89,684,313...89,684,381
Ensembl chr 9:89,684,313...89,684,381
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G |
Mir188 |
microRNA 188 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR188 mRNA |
CTD |
PMID:27629361 |
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NCBI chr X:7,114,228...7,114,295
Ensembl chr X:7,114,228...7,114,295
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Mir1894 |
microRNA 1894 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR1894 mRNA |
CTD |
PMID:27629361 |
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NCBI chr17:36,228,781...36,228,861
Ensembl chr17:36,228,781...36,228,861
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G |
Mir1896 |
microRNA 1896 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR1896 mRNA |
CTD |
PMID:27629361 |
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NCBI chr13:21,629,330...21,629,410
Ensembl chr13:21,629,330...21,629,410
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Mir1901 |
microRNA 1901 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR1901 mRNA |
CTD |
PMID:27629361 |
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NCBI chr18:11,973,418...11,973,495
Ensembl chr18:11,973,418...11,973,495
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G |
Mir191 |
microRNA 191 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR191 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 9:108,445,518...108,445,591
Ensembl chr 9:108,445,518...108,445,591
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G |
Mir192 |
microRNA 192 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of MIR192 mRNA dapagliflozin inhibits the reaction [Streptozocin results in increased expression of MIR192 mRNA] |
CTD |
PMID:37352119 |
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NCBI chr19:6,314,874...6,314,962
Ensembl chr19:6,314,874...6,314,962
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G |
Mir1930 |
microRNA 1930 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR1930 mRNA |
CTD |
PMID:27629361 |
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NCBI chr10:77,477,058...77,477,141
Ensembl chr10:77,477,058...77,477,141
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G |
Mir1934 |
microRNA 1934 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR1934 mRNA |
CTD |
PMID:27629361 |
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NCBI chr11:69,553,869...69,553,951
Ensembl chr11:69,553,869...69,553,951
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G |
Mir194-1 |
microRNA 194-1 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR194-1 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 1:185,045,516...185,045,582
Ensembl chr 1:185,045,516...185,045,582
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G |
Mir1945 |
microRNA 1945 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR1945 mRNA |
CTD |
PMID:27629361 |
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NCBI chr16:11,072,232...11,072,309
Ensembl chr16:11,072,232...11,072,309
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Mir1955 |
microRNA 1955 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR1955 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 2:92,022,322...92,022,419
Ensembl chr 2:92,022,322...92,022,419
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Mir1962 |
microRNA 1962 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR1962 mRNA |
CTD |
PMID:27629361 |
|
NCBI chr 7:135,167,891...135,168,011
Ensembl chr 7:135,167,891...135,168,011
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Mir196a-1 |
microRNA 196a-1 |
decreases expression |
EXP |
Streptozocin results in decreased expression of MIR196A-1 mRNA |
CTD |
PMID:27629361 |
|
NCBI chr11:96,155,990...96,156,091
Ensembl chr11:96,155,990...96,156,091
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G |
Mir1981 |
microRNA 1981 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR1981 mRNA |
CTD |
PMID:27629361 |
|
NCBI chr 1:184,554,604...184,554,685
Ensembl chr 1:184,554,604...184,554,685
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G |
Mir1982 |
microRNA 1982 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR1982 mRNA |
CTD |
PMID:27629361 |
|
NCBI chr10:80,664,631...80,664,704
Ensembl chr10:80,664,631...80,664,704
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Mir1b |
microRNA 1b |
increases expression |
EXP |
Streptozocin results in increased expression of MIR1B mRNA |
CTD |
PMID:27629361 |
|
NCBI chr18:10,785,446...10,785,567
Ensembl chr18:10,785,446...10,785,567
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G |
Mir200a |
microRNA 200a |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of MIR200A mRNA 2,5-dihydroxybenzoic acid promotes the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of MIR200A]; [Streptozocin co-treated with Niacinamide] results in increased expression of MIR200A; Metformin promotes the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of MIR200A] |
CTD |
PMID:27629361 PMID:37120126 |
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NCBI chr 4:156,139,353...156,139,442
Ensembl chr 4:156,139,353...156,139,442
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G |
Mir203 |
microRNA 203 |
affects expression |
EXP |
Streptozocin affects the expression of MIR203 mRNA |
CTD |
PMID:27629361 |
|
NCBI chr12:112,097,314...112,097,389
Ensembl chr12:112,097,314...112,097,389
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G |
Mir205 |
microRNA 205 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR205 mRNA |
CTD |
PMID:27629361 |
|
NCBI chr 1:193,189,771...193,189,838
Ensembl chr 1:193,189,771...193,189,838
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G |
Mir20b |
microRNA 20b |
decreases expression |
EXP |
Streptozocin results in decreased expression of MIR20B mRNA |
CTD |
PMID:27629361 |
|
NCBI chr X:51,830,990...51,831,069
Ensembl chr X:51,830,990...51,831,069
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G |
Mir2139 |
microRNA 2139 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR2139 mRNA |
CTD |
PMID:27629361 |
|
NCBI chr 4:139,694,837...139,694,931
Ensembl chr 4:139,694,837...139,694,931
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G |
Mir216a |
microRNA 216a |
increases expression |
EXP |
Streptozocin results in increased expression of MIR216A mRNA |
CTD |
PMID:27629361 |
|
NCBI chr11:28,707,012...28,707,083
Ensembl chr11:28,707,012...28,707,083
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G |
Mir217 |
microRNA 217 |
increases expression decreases expression |
EXP ISO |
Streptozocin results in increased expression of MIR217 mRNA Streptozocin results in decreased expression of MIR217 mRNA |
CTD |
PMID:27629361 PMID:33283391 |
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NCBI chr11:28,713,728...28,713,835
Ensembl chr11:28,713,728...28,713,835
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G |
Mir218-2 |
microRNA 218-2 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR218-2 mRNA |
CTD |
PMID:27629361 |
|
NCBI chr11:35,507,643...35,507,752
Ensembl chr11:35,507,643...35,507,752
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G |
Mir219a-1 |
microRNA 219a-1 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR219A-1 mRNA |
CTD |
PMID:27629361 |
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NCBI chr17:34,243,957...34,244,066
Ensembl chr17:34,243,957...34,244,066
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G |
Mir21a |
microRNA 21a |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of MIR21 mRNA dapagliflozin inhibits the reaction [Streptozocin results in increased expression of MIR21 mRNA] |
CTD |
PMID:37352119 |
|
NCBI chr11:86,474,893...86,474,984
Ensembl chr11:86,474,893...86,474,984
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G |
Mir222 |
microRNA 222 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR222 mRNA |
CTD |
PMID:27629361 |
|
NCBI chr X:19,013,132...19,013,210
Ensembl chr X:19,013,132...19,013,210
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G |
Mir27a |
microRNA 27a |
decreases expression multiple interactions |
EXP ISO |
Streptozocin results in decreased expression of MIR27A mRNA SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of MIR27A mRNA] |
CTD |
PMID:27629361 |
|
NCBI chr 8:84,935,301...84,935,387
Ensembl chr 8:84,935,301...84,935,387
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G |
Mir28b |
microRNA 28b |
decreases expression |
EXP |
Streptozocin results in decreased expression of MIR28B mRNA |
CTD |
PMID:27629361 |
|
NCBI chr 8:73,743,140...73,743,219
Ensembl chr 8:73,743,140...73,743,219
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Mir293 |
microRNA 293 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR293 mRNA |
CTD |
PMID:27629361 |
|
NCBI chr 7:3,269,017...3,269,096
Ensembl chr 7:3,269,017...3,269,096
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G |
Mir298 |
microRNA 298 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR298 mRNA |
CTD |
PMID:27629361 |
|
NCBI chr 2:174,109,297...174,109,378
Ensembl chr 2:174,109,297...174,109,378
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G |
Mir29a |
microRNA 29a |
decreases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of MIR29A mRNA MIR29A mRNA inhibits the reaction [Streptozocin results in decreased expression of PPARG mRNA]; MIR29A mRNA inhibits the reaction [Streptozocin results in decreased expression of PPARG protein]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of CNR1 mRNA]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of CNR1 protein]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of COL4A2 mRNA]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of JUN mRNA]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of TNF mRNA] |
CTD |
PMID:30642005 |
|
NCBI chr 6:31,039,595...31,039,682
Ensembl chr 6:31,039,595...31,039,682
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G |
Mir29c |
microRNA 29c |
increases expression |
EXP |
Streptozocin results in increased expression of MIR29C mRNA |
CTD |
PMID:27629361 |
|
NCBI chr 1:194,719,855...194,719,942
Ensembl chr 1:194,719,855...194,719,942
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G |
Mir302a |
microRNA 302a |
increases expression |
EXP |
Streptozocin results in increased expression of MIR302A mRNA |
CTD |
PMID:27629361 |
|
NCBI chr 3:127,339,145...127,339,213
Ensembl chr 3:127,339,145...127,339,213
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G |
Mir302c |
microRNA 302c |
increases expression |
EXP |
Streptozocin results in increased expression of MIR302C mRNA |
CTD |
PMID:27629361 |
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NCBI chr 3:127,339,012...127,339,079
Ensembl chr 3:127,339,012...127,339,079
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G |
Mir3060 |
microRNA 3060 |
decreases expression |
EXP |
Streptozocin results in decreased expression of MIR3060 mRNA |
CTD |
PMID:27629361 |
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NCBI chr11:4,089,364...4,089,446
Ensembl chr11:4,089,364...4,089,446
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G |
Mir3063 |
microRNA 3063 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR3063 mRNA |
CTD |
PMID:27629361 |
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NCBI chr11:95,854,118...95,854,209
Ensembl chr11:95,854,118...95,854,209
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G |
Mir3067 |
microRNA 3067 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR3067 mRNA |
CTD |
PMID:27629361 |
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NCBI chr12:81,212,925...81,213,008
Ensembl chr12:81,212,925...81,213,008
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G |
Mir3075 |
microRNA 3075 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR3075 mRNA |
CTD |
PMID:27629361 |
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NCBI chr14:25,534,863...25,534,947
Ensembl chr14:25,534,863...25,534,947
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G |
Mir3078 |
microRNA 3078 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR3078 mRNA |
CTD |
PMID:27629361 |
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NCBI chr14:64,828,634...64,828,720
Ensembl chr14:64,828,634...64,828,720
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Mir3083 |
microRNA 3083 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR3083 mRNA |
CTD |
PMID:27629361 |
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NCBI chr17:27,167,030...27,167,093
Ensembl chr17:27,167,030...27,167,093
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G |
Mir3086 |
microRNA 3086 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR3086 mRNA |
CTD |
PMID:27629361 |
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NCBI chr19:58,900,105...58,900,191
Ensembl chr19:58,900,105...58,900,191
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G |
Mir3088 |
microRNA 3088 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR3088 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 2:28,623,290...28,623,363
Ensembl chr 2:28,623,290...28,623,363
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Mir3089 |
microRNA 3089 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR3089 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 2:30,611,222...30,611,305
Ensembl chr 2:30,611,222...30,611,305
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G |
Mir3090 |
microRNA 3090 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR3090 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 2:133,406,628...133,406,714
Ensembl chr 2:133,406,628...133,406,714
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G |
Mir3091 |
microRNA 3091 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR3091 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 2:179,899,329...179,899,404
Ensembl chr 2:179,899,329...179,899,404
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Mir3093 |
microRNA 3093 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR3093 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 3:88,122,478...88,122,564
Ensembl chr 3:88,122,478...88,122,564
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G |
Mir3094 |
microRNA 3094 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR3094 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 4:40,993,695...40,993,758
Ensembl chr 4:40,993,695...40,993,758
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G |
Mir3095 |
microRNA 3095 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR3095 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 4:58,441,012...58,441,098
Ensembl chr 4:58,441,012...58,441,098
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G |
Mir3097 |
microRNA 3097 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR3097 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 5:35,178,393...35,178,459
Ensembl chr 5:35,178,393...35,178,459
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G |
Mir3102 |
microRNA 3102 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR3102 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 7:100,531,513...100,531,616
Ensembl chr 7:100,531,513...100,531,616
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Mir3103 |
microRNA 3103 |
decreases expression |
EXP |
Streptozocin results in decreased expression of MIR3103 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 7:127,887,541...127,887,607
Ensembl chr 7:127,887,541...127,887,607
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G |
Mir3108 |
microRNA 3108 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR3108 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 8:109,663,492...109,663,570
Ensembl chr 8:109,663,492...109,663,570
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Mir3109 |
microRNA 3109 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR3109 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 9:69,364,226...69,364,313
Ensembl chr 9:69,364,226...69,364,313
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Mir3110 |
microRNA 3110 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR3110 mRNA |
CTD |
PMID:27629361 |
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NCBI chr X:37,299,318...37,299,397
Ensembl chr X:37,299,318...37,299,397
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Mir3113 |
microRNA 3113 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR3113 mRNA |
CTD |
PMID:27629361 |
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NCBI chr X:150,642,558...150,642,633
Ensembl chr X:150,642,558...150,642,633
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Mir32 |
microRNA 32 |
increases expression |
ISO |
Streptozocin results in increased expression of MIR32 mRNA |
CTD |
PMID:32959695 |
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NCBI chr 4:56,895,229...56,895,298
Ensembl chr 4:56,895,229...56,895,298
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Mir322 |
microRNA 322 |
decreases expression multiple interactions |
EXP ISO |
Streptozocin results in decreased expression of MIR322 mRNA SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of MIR322 mRNA] |
CTD |
PMID:27629361 |
|
NCBI chr X:52,143,132...52,143,226
Ensembl chr X:52,143,132...52,143,226
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G |
Mir323 |
microRNA 323 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR323 mRNA |
CTD |
PMID:27629361 |
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NCBI chr12:109,678,942...109,679,027
Ensembl chr12:109,678,942...109,679,027
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G |
Mir33 |
microRNA 33 |
multiple interactions |
ISO |
[Fructose co-treated with Streptozocin] results in increased expression of MIR33A mRNA; Ghrelin inhibits the reaction [[Fructose co-treated with Streptozocin] results in increased expression of MIR33A mRNA] |
CTD |
PMID:31468622 |
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NCBI chr15:82,082,323...82,082,391
Ensembl chr15:82,082,323...82,082,391
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Mir330 |
microRNA 330 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR330 mRNA |
CTD |
PMID:27629361 |
|
NCBI chr 7:18,915,390...18,915,487
Ensembl chr 7:18,915,390...18,915,487
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Mir341 |
microRNA 341 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR341 mRNA |
CTD |
PMID:27629361 |
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NCBI chr12:109,577,934...109,578,029
Ensembl chr12:109,577,934...109,578,029
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Mir344f |
microRNA Mir344f |
increases expression |
EXP |
Streptozocin results in increased expression of MIR344F mRNA |
CTD |
PMID:27629361 |
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NCBI chr 7:61,695,929...61,695,996
Ensembl chr 7:61,695,929...61,695,996
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G |
Mir344g |
microRNA 344g |
increases expression |
EXP |
Streptozocin results in increased expression of MIR344G mRNA |
CTD |
PMID:27629361 |
|
NCBI chr 7:61,632,037...61,632,107
Ensembl chr 7:61,632,037...61,632,107
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G |
Mir3475 |
microRNA 3475 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR3475 mRNA |
CTD |
PMID:27629361 |
|
NCBI chr X:139,211,697...139,211,761
Ensembl chr X:139,211,697...139,211,761
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Mir375 |
microRNA 375 |
increases expression |
ISO |
Streptozocin results in increased expression of MIR375 mRNA |
CTD |
PMID:27521901 |
|
NCBI chr 1:74,939,817...74,939,880
Ensembl chr 1:74,939,817...74,939,880
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Mir377 |
microRNA 377 |
multiple interactions |
EXP |
[Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of MIR377]; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of MIR377 |
CTD |
PMID:38282657 |
|
NCBI chr12:109,706,944...109,707,011
Ensembl chr12:109,706,944...109,707,011
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Mir379 |
microRNA 379 |
multiple interactions |
EXP |
[Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of MIR379]; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of MIR379 |
CTD |
PMID:38282657 |
|
NCBI chr12:109,675,494...109,675,559
Ensembl chr12:109,675,494...109,675,559
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Mir380 |
microRNA 380 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR380 mRNA |
CTD |
PMID:27629361 |
|
NCBI chr12:109,678,237...109,678,297
Ensembl chr12:109,678,237...109,678,297
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Mir384 |
microRNA 384 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR384 mRNA |
CTD |
PMID:27629361 |
|
NCBI chr X:104,387,888...104,387,975
Ensembl chr X:104,387,888...104,387,975
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G |
Mir3962 |
microRNA 3962 |
decreases expression |
EXP |
Streptozocin results in decreased expression of MIR3962 mRNA |
CTD |
PMID:27629361 |
|
NCBI chr 1:194,504,309...194,504,372
Ensembl chr 1:194,504,309...194,504,372
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G |
Mir3966 |
microRNA 3966 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR3966 mRNA |
CTD |
PMID:27629361 |
|
NCBI chr10:97,259,340...97,259,424
Ensembl chr10:97,259,340...97,259,424
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G |
Mir3968 |
microRNA 3968 |
decreases expression |
EXP |
Streptozocin results in decreased expression of MIR3968 mRNA |
CTD |
PMID:27629361 |
|
NCBI chr11:115,338,787...115,338,886
Ensembl chr11:115,338,787...115,338,886
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Mir412 |
microRNA 412 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR412 mRNA |
CTD |
PMID:27629361 |
|
NCBI chr12:109,709,723...109,709,802
Ensembl chr12:109,709,723...109,709,802
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Mir421 |
microRNA 421 |
decreases expression |
EXP |
Streptozocin results in decreased expression of MIR421 mRNA |
CTD |
PMID:27629361 |
|
NCBI chr X:102,616,527...102,616,602
Ensembl chr X:102,616,527...102,616,602
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Mir433 |
microRNA 433 |
decreases expression |
EXP |
Streptozocin results in decreased expression of MIR433 mRNA |
CTD |
PMID:27629361 |
|
NCBI chr12:109,558,149...109,558,272
Ensembl chr12:109,558,149...109,558,272
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Mir434 |
microRNA 434 |
decreases expression |
EXP |
Streptozocin results in decreased expression of MIR434 mRNA |
CTD |
PMID:27629361 |
|
NCBI chr12:109,560,940...109,561,033
Ensembl chr12:109,560,940...109,561,033
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Mir448 |
microRNA 448 |
multiple interactions increases expression |
ISO EXP |
SOD1 protein inhibits the reaction [Streptozocin results in increased expression of MIR448 mRNA] |
CTD |
PMID:27629361 |
|
NCBI chr X:145,941,206...145,941,317
Ensembl chr X:145,941,206...145,941,317
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Mir450b |
microRNA 450b |
decreases expression |
EXP |
Streptozocin results in decreased expression of MIR450B mRNA |
CTD |
PMID:27629361 |
|
NCBI chr X:52,136,874...52,136,955
Ensembl chr X:52,136,874...52,136,955
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G |
Mir451a |
microRNA 451a |
increases expression |
EXP |
Streptozocin results in increased expression of MIR451A mRNA |
CTD |
PMID:27629361 |
|
NCBI chr11:77,963,996...77,964,067
Ensembl chr11:77,963,996...77,964,067
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Mir452 |
microRNA 452 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR452 mRNA |
CTD |
PMID:27629361 |
|
NCBI chr X:71,305,830...71,305,914
Ensembl chr X:71,305,830...71,305,914
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Mir466m |
microRNA 466m |
decreases expression |
EXP |
Streptozocin results in decreased expression of MIR466M mRNA |
CTD |
PMID:27629361 |
|
NCBI chr 2:10,471,474...10,471,557
Ensembl chr 2:10,471,474...10,471,557
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G |
Mir467c |
microRNA 467c |
increases expression |
EXP |
Streptozocin results in increased expression of MIR467C mRNA |
CTD |
PMID:27629361 |
|
NCBI chr 2:10,478,742...10,478,838
Ensembl chr 2:10,478,742...10,478,838
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G |
Mir467e |
microRNA 467e |
decreases expression |
EXP |
Streptozocin results in decreased expression of MIR467E mRNA |
CTD |
PMID:27629361 |
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NCBI chr 2:10,510,532...10,510,618
Ensembl chr 2:10,510,532...10,510,618
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Mir468 |
microRNA 468 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR468 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 6:81,873,580...81,873,657
Ensembl chr 6:81,873,580...81,873,657
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Mir471 |
microRNA 471 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR471 mRNA |
CTD |
PMID:27629361 |
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NCBI chr X:65,836,201...65,836,267
Ensembl chr X:65,836,201...65,836,267
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Mir490 |
microRNA 490 |
decreases expression |
EXP |
Streptozocin results in decreased expression of MIR490 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 6:36,398,677...36,398,760
Ensembl chr 6:36,398,677...36,398,760
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Mir494 |
microRNA 494 |
multiple interactions |
EXP |
[Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of MIR494]; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of MIR494 |
CTD |
PMID:38282657 |
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NCBI chr12:109,681,752...109,681,836
Ensembl chr12:109,681,752...109,681,836
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Mir495 |
microRNA 495 |
multiple interactions |
EXP |
[Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of MIR495]; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of MIR495 |
CTD |
PMID:38282657 |
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NCBI chr12:109,685,188...109,685,250
Ensembl chr12:109,685,188...109,685,250
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Mir497 |
microRNA 497 |
multiple interactions decreases expression |
ISO |
MIR497 inhibits the reaction [Streptozocin results in decreased expression of MIR497 protein]; MIR497 inhibits the reaction [Streptozocin results in increased expression of USP15 mRNA]; MIR497 inhibits the reaction [Streptozocin results in increased expression of USP15 protein] |
CTD |
PMID:35478295 |
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NCBI chr11:70,125,543...70,125,626
Ensembl chr11:70,125,543...70,125,626
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Mir499 |
microRNA 499 |
decreases expression |
EXP |
Streptozocin results in decreased expression of MIR499 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 2:155,464,800...155,464,878
Ensembl chr 2:155,464,800...155,464,878
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Mir504 |
microRNA 504 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR504 mRNA |
CTD |
PMID:27629361 |
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NCBI chr X:58,143,018...58,143,096
Ensembl chr X:58,143,018...58,143,096
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Mir5103 |
microRNA 5103 |
decreases expression |
EXP |
Streptozocin results in decreased expression of MIR5103 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 1:34,472,202...34,472,280
Ensembl chr 1:34,472,202...34,472,280
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Mir5107 |
microRNA 5107 |
decreases expression |
EXP |
Streptozocin results in decreased expression of MIR5107 mRNA |
CTD |
PMID:27629361 |
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NCBI chr18:60,945,148...60,945,235
Ensembl chr18:60,945,148...60,945,235
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Mir511 |
microRNA 511 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR511 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 2:14,265,814...14,265,892
Ensembl chr 2:14,265,814...14,265,892
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Mir5127 |
microRNA 5127 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR5127 mRNA |
CTD |
PMID:27629361 |
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NCBI chr18:82,035,225...82,035,295
Ensembl chr18:82,035,225...82,035,295
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Mir544 |
microRNA 544 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR544 mRNA |
CTD |
PMID:27629361 |
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NCBI chr12:109,695,759...109,695,836
Ensembl chr12:109,695,759...109,695,836
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Mir546 |
microRNA 546 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR546 mRNA |
CTD |
PMID:27629361 |
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NCBI chr10:126,834,309...126,834,429
Ensembl chr10:126,834,309...126,834,429
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Mir547 |
microRNA 547 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR547 mRNA |
CTD |
PMID:27629361 |
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NCBI chr X:67,031,980...67,032,057
Ensembl chr X:67,031,980...67,032,057
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Mir5620 |
microRNA 5620 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR5620 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 7:7,301,890...7,301,945
Ensembl chr 7:7,301,890...7,301,945
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Mir5621 |
microRNA 5621 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR5621 mRNA |
CTD |
PMID:27629361 |
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NCBI chr11:115,686,650...115,686,712
Ensembl chr11:115,686,650...115,686,712
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Mir5625 |
microRNA 5625 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR5625 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 5:30,805,280...30,805,359
Ensembl chr 5:30,805,280...30,805,359
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Mir582 |
microRNA 582 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR582 mRNA |
CTD |
PMID:27629361 |
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NCBI chr13:109,461,278...109,461,358
Ensembl chr13:109,461,278...109,461,358
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Mir666 |
microRNA 666 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR666 mRNA |
CTD |
PMID:27629361 |
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NCBI chr12:109,683,519...109,683,617
Ensembl chr12:109,683,519...109,683,617
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Mir669j |
microRNA 669j |
increases expression |
EXP |
Streptozocin results in increased expression of MIR669J mRNA |
CTD |
PMID:27629361 |
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NCBI chr 2:10,482,721...10,482,841
Ensembl chr 2:10,482,721...10,482,841
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Mir669n |
microRNA 669n |
decreases expression |
EXP |
Streptozocin results in decreased expression of MIR669N mRNA |
CTD |
PMID:27629361 |
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NCBI chr 3:115,773,551...115,773,604
Ensembl chr 3:115,773,551...115,773,604
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Mir671 |
microRNA 671 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR671 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 5:24,797,112...24,797,209
Ensembl chr 5:24,797,112...24,797,209
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Mir677 |
microRNA 677 |
decreases expression |
EXP |
Streptozocin results in decreased expression of MIR677 mRNA |
CTD |
PMID:27629361 |
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NCBI chr10:127,921,155...127,921,232
Ensembl chr10:127,921,155...127,921,232 Ensembl chr10:127,921,155...127,921,232
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Mir679 |
microRNA 679 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR679 mRNA |
CTD |
PMID:27629361 |
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NCBI chr12:109,682,011...109,682,084
Ensembl chr12:109,682,011...109,682,084
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Mir697 |
microRNA 697 |
decreases expression |
EXP |
Streptozocin results in decreased expression of MIR697 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 4:124,625,487...124,625,595
Ensembl chr 4:124,625,487...124,625,595
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Mir702 |
microRNA 702 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR702 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 5:137,020,287...137,020,395
Ensembl chr 5:137,020,287...137,020,395
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Mir705 |
microRNA 705 |
decreases expression |
EXP |
Streptozocin results in decreased expression of MIR705 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 6:85,313,274...85,313,355
Ensembl chr 6:85,313,274...85,313,355
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Mir718 |
microRNA 718 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR718 mRNA |
CTD |
PMID:27629361 |
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NCBI chr X:73,067,455...73,067,542
Ensembl chr X:73,067,455...73,067,542
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Mir741 |
microRNA 741 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR741 mRNA |
CTD |
PMID:27629361 |
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NCBI chr X:65,840,411...65,840,481
Ensembl chr X:65,840,411...65,840,481
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Mir743b |
microRNA 743b |
increases expression |
EXP |
Streptozocin results in increased expression of MIR743B mRNA |
CTD |
PMID:27629361 |
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NCBI chr X:65,820,862...65,820,938
Ensembl chr X:65,820,862...65,820,938
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Mir744 |
microRNA 744 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR744 mRNA |
CTD |
PMID:27629361 |
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NCBI chr11:65,625,559...65,625,658
Ensembl chr11:65,625,559...65,625,658
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Mir871 |
microRNA 871 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR871 mRNA |
CTD |
PMID:27629361 |
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NCBI chr X:65,854,034...65,854,110
Ensembl chr X:65,854,034...65,854,110
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Mir873a |
microRNA 873a |
increases expression |
EXP |
Streptozocin results in increased expression of MIR873A mRNA |
CTD |
PMID:27629361 |
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NCBI chr 4:36,668,510...36,668,586
Ensembl chr 4:36,668,510...36,668,586
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Mir875 |
microRNA 875 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR875 mRNA |
CTD |
PMID:27629361 |
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NCBI chr15:35,661,116...35,661,193
Ensembl chr15:35,661,116...35,661,193
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Mir879 |
microRNA 879 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR879 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 5:9,425,704...9,425,779
Ensembl chr 5:9,425,704...9,425,779
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Mir93 |
microRNA 93 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR93 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 5:138,163,785...138,163,872
Ensembl chr 5:138,163,785...138,163,872
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Mir96 |
microRNA 96 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR96 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 6:30,169,445...30,169,550
Ensembl chr 6:30,169,445...30,169,550
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Mir98 |
microRNA 98 |
decreases expression |
EXP |
Streptozocin results in decreased expression of MIR98 mRNA |
CTD |
PMID:27629361 |
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NCBI chr X:150,696,210...150,696,317
Ensembl chr X:150,696,210...150,696,317
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Mknk2 |
MAP kinase-interacting serine/threonine kinase 2 |
increases expression |
ISO |
Streptozocin results in increased expression of MKNK2 mRNA |
CTD |
PMID:25905778 |
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NCBI chr10:80,501,152...80,512,264
Ensembl chr10:80,501,161...80,513,946
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Mme |
membrane metallo endopeptidase |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of MME protein Trientine inhibits the reaction [Streptozocin results in decreased expression of MME protein] |
CTD |
PMID:19634143 |
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NCBI chr 3:63,202,632...63,291,134
Ensembl chr 3:63,148,958...63,293,451
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Mmp13 |
matrix metallopeptidase 13 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of MMP13 mRNA esculetin inhibits the reaction [Streptozocin results in increased expression of MMP13 mRNA] |
CTD |
PMID:21450970 |
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NCBI chr 9:7,272,514...7,283,333
Ensembl chr 9:7,272,514...7,283,331
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Mmp1b |
matrix metallopeptidase 1b (interstitial collagenase) |
increases expression |
ISO |
Streptozocin results in increased expression of MMP1 protein |
CTD |
PMID:35993117 |
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NCBI chr 9:7,367,670...7,388,026
Ensembl chr 9:7,368,239...7,388,047
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Mmp2 |
matrix metallopeptidase 2 |
multiple interactions increases expression decreases expression increases activity decreases secretion |
ISO EXP |
PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of MMP2 mRNA] Streptozocin results in decreased expression of MMP2 mRNA; Streptozocin results in decreased expression of MMP2 protein benazepril inhibits the reaction [Streptozocin results in decreased expression of MMP2 mRNA]; benazepril inhibits the reaction [Streptozocin results in decreased expression of MMP2 protein]; dapagliflozin inhibits the reaction [Streptozocin results in increased expression of MMP2 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of MMP2 protein]; Olive Oil inhibits the reaction [Streptozocin results in increased activity of MMP2 protein]; rhapontin inhibits the reaction [Streptozocin results in increased expression of MMP2 mRNA]; Tropisetron inhibits the reaction [Streptozocin results in decreased expression of MMP2 mRNA] Streptozocin results in increased expression of MMP2 mRNA; Streptozocin results in increased expression of MMP2 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Raloxifene Hydrochloride inhibits the reaction [Streptozocin results in decreased secretion of MMP2 protein]]; CEBPB protein inhibits the reaction [Streptozocin results in decreased expression of MMP2 protein]; ESR2 protein affects the reaction [Raloxifene Hydrochloride inhibits the reaction [Streptozocin results in decreased secretion of MMP2 protein]]; Raloxifene Hydrochloride inhibits the reaction [Streptozocin results in decreased expression of MMP2 mRNA]; Raloxifene Hydrochloride inhibits the reaction [Streptozocin results in decreased secretion of MMP2 protein]; Valsartan inhibits the reaction [Streptozocin results in decreased expression of MMP2 protein] |
CTD |
PMID:16732983 PMID:20446767 PMID:20821936 PMID:23471663 PMID:25246140 PMID:29266779 PMID:29682576 PMID:32662907 PMID:33387473 PMID:37352119 More...
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NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048
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Mmp3 |
matrix metallopeptidase 3 |
increases expression multiple interactions decreases expression |
EXP ISO |
Streptozocin results in increased expression of MMP3 mRNA PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of MMP3 mRNA] Streptozocin results in decreased expression of MMP3 mRNA |
CTD |
PMID:18246672 PMID:20446767 |
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NCBI chr 9:7,445,845...7,455,975
Ensembl chr 9:7,445,822...7,455,975
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Mmp7 |
matrix metallopeptidase 7 |
multiple interactions increases expression |
ISO EXP |
PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of MMP7 mRNA] [Streptozocin co-treated with Dietary Fats] results in increased expression of MMP7 mRNA |
CTD |
PMID:20446767 PMID:29127188 |
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NCBI chr 9:7,692,095...7,699,587
Ensembl chr 9:7,692,091...7,699,587
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Mmp9 |
matrix metallopeptidase 9 |
multiple interactions increases expression increases activity decreases expression |
ISO EXP |
PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of MMP9 mRNA] Streptozocin results in increased expression of MMP9 mRNA; Streptozocin results in increased expression of MMP9 protein [Streptozocin co-treated with Tobacco Smoke Pollution] results in increased expression of MMP9 protein; idebenone inhibits the reaction [Streptozocin results in increased expression of MMP9 protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of MMP9 protein]; Olive Oil inhibits the reaction [Streptozocin results in increased activity of MMP9 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of MMP9 mRNA]; Rosiglitazone inhibits the reaction [Streptozocin deficiency results in increased expression of MMP9 mRNA]; Simvastatin inhibits the reaction [Streptozocin results in increased expression of MMP9 mRNA]; Tropisetron inhibits the reaction [Streptozocin results in decreased expression of MMP9 mRNA] [Dietary Fats co-treated with Streptozocin] results in increased expression of MMP9 mRNA; formononetin inhibits the reaction [Streptozocin results in increased expression of MMP9 mRNA]; formononetin inhibits the reaction [Streptozocin results in increased expression of MMP9 protein]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of MMP9 mRNA]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Streptozocin promotes the reaction [JUN protein binds to MMP9 promoter]]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Streptozocin promotes the reaction [RELA protein binds to MMP9 promoter]]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Streptozocin results in increased expression of MMP9 mRNA]; SIRT1 protein inhibits the reaction [Streptozocin promotes the reaction [PARP1 protein binds to MMP9 promoter]]; Streptozocin promotes the reaction [JUN protein binds to MMP9 promoter]; Streptozocin promotes the reaction [PARP1 protein binds to MMP9 promoter]; Streptozocin promotes the reaction [RELA protein binds to MMP9 promoter] |
CTD |
PMID:19236438 PMID:19820293 PMID:20446767 PMID:22191573 PMID:25246140 PMID:28478229 PMID:28648635 PMID:29682576 PMID:29988851 PMID:30421503 PMID:33387473 PMID:35315182 More...
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NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
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Mmrn1 |
multimerin 1 |
increases expression |
ISO |
Streptozocin results in increased expression of MMRN1 protein |
CTD |
PMID:21450970 |
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NCBI chr 6:60,921,301...60,966,362
Ensembl chr 6:60,901,960...60,966,362
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Mogat1 |
monoacylglycerol O-acyltransferase 1 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of MOGAT1 mRNA |
CTD |
PMID:29127188 |
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NCBI chr 1:78,487,697...78,597,882
Ensembl chr 1:78,487,628...78,514,810
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Mpg |
N-methylpurine-DNA glycosylase |
affects response to substance |
EXP |
MPG protein affects the susceptibility to Streptozocin |
CTD |
PMID:17098815 |
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NCBI chr11:32,176,505...32,182,702
Ensembl chr11:32,176,505...32,182,700
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Mpo |
myeloperoxidase |
multiple interactions increases activity |
EXP ISO |
[Streptozocin co-treated with Dextran Sulfate] results in increased activity of MPO protein; bisphenol A diglycidyl ether inhibits the reaction [Lisinopril inhibits the reaction [Streptozocin results in increased activity of MPO protein]]; bisphenol A diglycidyl ether inhibits the reaction [Telmisartan inhibits the reaction [Streptozocin results in increased activity of MPO protein]]; Donepezil inhibits the reaction [Streptozocin results in increased activity of MPO protein]; Lisinopril inhibits the reaction [Streptozocin results in increased activity of MPO protein]; Telmisartan inhibits the reaction [Streptozocin results in increased activity of MPO protein] Streptozocin results in increased expression of and results in increased activity of MPO protein |
CTD |
PMID:23060470 PMID:24924950 PMID:34039237 PMID:34964214 |
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NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239
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Mpped1 |
metallophosphoesterase domain containing 1 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of MPPED1 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of MPPED1 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr15:83,656,256...83,742,688
Ensembl chr15:83,663,668...83,742,695
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Mpz |
myelin protein zero |
multiple interactions decreases expression |
ISO |
20-alpha-Dihydroprogesterone inhibits the reaction [Streptozocin results in decreased expression of MPZ mRNA]; Progesterone inhibits the reaction [Streptozocin results in decreased expression of MPZ mRNA] |
CTD |
PMID:17187935 |
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NCBI chr 1:170,978,282...170,988,699
Ensembl chr 1:170,978,280...170,988,699
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Mrc1 |
mannose receptor, C type 1 |
decreases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of MRC1 mRNA AM6545 inhibits the reaction [Streptozocin results in decreased expression of MRC1 mRNA]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in decreased expression of MRC1 mRNA]]; Perindopril inhibits the reaction [Streptozocin results in decreased expression of MRC1 mRNA]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in decreased expression of MRC1 mRNA]] |
CTD |
PMID:30184259 |
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NCBI chr 2:14,234,225...14,336,834
Ensembl chr 2:14,234,203...14,336,868
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Mroh6 |
maestro heat-like repeat family member 6 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of MROH6 mRNA |
CTD |
PMID:33484791 |
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NCBI chr15:75,753,085...75,762,544
Ensembl chr15:75,755,986...75,760,619
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Mrpl14 |
mitochondrial ribosomal protein L14 |
affects expression |
EXP |
Streptozocin affects the expression of MRPL14 mRNA |
CTD |
PMID:18583417 |
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NCBI chr17:45,991,689...46,009,421
Ensembl chr17:45,997,248...46,009,421
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Mrpl18 |
mitochondrial ribosomal protein L18 |
affects expression |
EXP |
Streptozocin affects the expression of MRPL18 mRNA |
CTD |
PMID:18583417 |
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NCBI chr17:13,130,232...13,136,674
Ensembl chr17:13,130,236...13,135,232
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Mrpl42 |
mitochondrial ribosomal protein L42 |
affects expression |
EXP |
Streptozocin affects the expression of MRPL42 mRNA |
CTD |
PMID:18583417 |
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NCBI chr10:95,316,667...95,337,811
Ensembl chr10:95,316,667...95,337,802
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G |
Mrps7 |
mitchondrial ribosomal protein S7 |
affects expression |
EXP |
Streptozocin affects the expression of MRPS7 mRNA |
CTD |
PMID:18583417 |
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NCBI chr11:115,494,966...115,498,862
Ensembl chr11:115,494,751...115,498,862
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G |
Ms4a3 |
membrane-spanning 4-domains, subfamily A, member 3 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of MS4A3 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of MS4A3 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr19:11,606,863...11,618,215
Ensembl chr19:11,606,860...11,618,215
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G |
Ms4a6c |
membrane-spanning 4-domains, subfamily A, member 6C |
multiple interactions |
ISO |
[Resveratrol co-treated with Streptozocin] results in increased expression of MS4A6A mRNA |
CTD |
PMID:25905778 |
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NCBI chr19:11,446,718...11,464,433
Ensembl chr19:11,446,730...11,459,556
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G |
Msln |
mesothelin |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of MSLN mRNA |
CTD |
PMID:29127188 |
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NCBI chr17:25,967,587...25,973,352
Ensembl chr17:25,967,587...25,973,352
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G |
Mt1 |
metallothionein 1 |
increases expression decreases expression multiple interactions |
ISO |
Streptozocin results in increased expression of MT1A mRNA Streptozocin results in decreased expression of MT1A mRNA vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of MT1A mRNA]; Zinc promotes the reaction [Streptozocin results in increased expression of MT1A mRNA] |
CTD |
PMID:16684804 PMID:19369054 PMID:24927960 |
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NCBI chr 8:94,905,214...94,906,955
Ensembl chr 8:94,905,710...94,906,955
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G |
Mt2 |
metallothionein 2 |
decreases expression |
ISO |
Streptozocin results in decreased expression of MT2A mRNA |
CTD |
PMID:24927960 |
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NCBI chr 8:94,899,246...94,900,195
Ensembl chr 8:94,899,292...94,900,196
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G |
Mt3 |
metallothionein 3 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of MT3 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of MT3 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 8:94,879,235...94,880,776
Ensembl chr 8:94,879,235...94,880,774
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G |
Mthfr |
methylenetetrahydrofolate reductase |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of MTHFR mRNA |
CTD |
PMID:29127188 |
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NCBI chr 4:148,123,534...148,144,019
Ensembl chr 4:148,123,534...148,144,008
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G |
Mtmr7 |
myotubularin related protein 7 |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in decreased expression of MTMR7 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 8:41,003,184...41,088,210
Ensembl chr 8:41,004,136...41,087,840
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G |
Mtor |
mechanistic target of rapamycin kinase |
multiple interactions decreases expression increases expression increases phosphorylation |
ISO EXP |
Resveratrol inhibits the reaction [Streptozocin results in decreased expression of MTOR mRNA]; Streptozocin results in decreased expression of and results in decreased phosphorylation of MTOR protein 5-Methoxypsoralen inhibits the reaction [Streptozocin results in increased expression of MTOR protein modified form]; [Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of MTOR protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of MTOR protein]; Tadalafil inhibits the reaction [Streptozocin results in increased expression of MTOR protein modified form] streptozocin increases increases phosphorylation of Mtor protein in heart |
CTD RGD |
PMID:26071184 PMID:33484791 PMID:34428446 PMID:38706688 PMID:36044268 |
RGD:156430337 |
NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140
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G |
Mtr |
5-methyltetrahydrofolate-homocysteine methyltransferase |
decreases activity multiple interactions |
ISO EXP |
Streptozocin results in decreased activity of MTR protein [Streptozocin co-treated with Dietary Fats] results in decreased expression of MTR mRNA |
CTD |
PMID:16835399 PMID:29127188 |
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NCBI chr13:12,196,217...12,273,090
Ensembl chr13:12,197,598...12,272,999
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G |
Myd88 |
myeloid differentiation primary response gene 88 |
multiple interactions increases expression |
EXP ISO |
[Dietary Fats co-treated with Streptozocin] results in increased expression of MYD88 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of MYD88 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of MYD88 protein; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of MYD88 mRNA]; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of MYD88 protein]; esculetin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of MYD88 mRNA]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of MYD88 mRNA] myrtenol inhibits the reaction [Streptozocin results in increased expression of MYD88 mRNA] |
CTD |
PMID:27769711 PMID:34477272 PMID:34610774 PMID:37482253 |
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NCBI chr 9:119,165,000...119,169,084
Ensembl chr 9:119,165,000...119,170,477
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G |
Myh3 |
myosin, heavy polypeptide 3, skeletal muscle, embryonic |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of MYH3 mRNA vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of MYH3 mRNA] |
CTD |
PMID:16684804 |
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NCBI chr11:66,969,101...66,993,117
Ensembl chr11:66,969,126...66,993,112
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G |
Myh6 |
myosin, heavy polypeptide 6, cardiac muscle, alpha |
multiple interactions decreases expression |
ISO |
Enalapril inhibits the reaction [Streptozocin results in decreased expression of MYH6 mRNA]; Enalapril inhibits the reaction [Streptozocin results in decreased expression of MYH6 protein]; Losartan inhibits the reaction [Streptozocin results in decreased expression of MYH6 mRNA]; Losartan inhibits the reaction [Streptozocin results in decreased expression of MYH6 protein] Streptozocin results in decreased expression of MYH6 mRNA; Streptozocin results in decreased expression of MYH6 protein |
CTD |
PMID:15362513 |
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NCBI chr14:55,179,378...55,205,553
Ensembl chr14:55,179,378...55,204,384
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G |
Myh7 |
myosin, heavy polypeptide 7, cardiac muscle, beta |
multiple interactions increases expression |
ISO |
Enalapril inhibits the reaction [Streptozocin results in increased expression of MYH7 mRNA]; Enalapril inhibits the reaction [Streptozocin results in increased expression of MYH7 protein]; Losartan inhibits the reaction [Streptozocin results in increased expression of MYH7 mRNA]; Losartan inhibits the reaction [Streptozocin results in increased expression of MYH7 protein] Streptozocin results in increased expression of MYH7 mRNA; Streptozocin results in increased expression of MYH7 protein |
CTD |
PMID:15362513 |
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NCBI chr14:55,208,141...55,232,083
Ensembl chr14:55,208,141...55,232,083
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G |
Naglu |
alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB) |
increases activity multiple interactions |
ISO |
Streptozocin results in increased activity of NAGLU protein Metformin inhibits the reaction [Streptozocin results in increased activity of NAGLU protein] |
CTD |
PMID:33639173 |
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NCBI chr11:100,960,918...100,968,483
Ensembl chr11:100,960,838...100,968,498
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G |
Nampt |
nicotinamide phosphoribosyltransferase |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of NAMPT mRNA [Streptozocin co-treated with Dietary Fats] results in increased expression of NAMPT protein; Rosiglitazone inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NAMPT protein] |
CTD |
PMID:25905778 PMID:29441829 |
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NCBI chr12:32,870,334...32,903,368
Ensembl chr12:32,869,544...32,903,348
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G |
Nat8 |
N-acetyltransferase 8 (GCN5-related) |
multiple interactions increases expression |
ISO |
[resveratrol co-treated with Streptozocin] results in decreased expression of NAT8 mRNA Streptozocin results in increased expression of NAT8 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 6:85,807,369...85,813,839
Ensembl chr 6:85,807,370...85,809,064
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G |
Nat8f3 |
N-acetyltransferase 8 (GCN5-related) family member 3 |
increases expression |
ISO |
Streptozocin results in increased expression of NAT8F3 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 6:85,737,613...85,742,726
Ensembl chr 6:85,709,495...85,742,736
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G |
Ncf1 |
neutrophil cytosolic factor 1 |
increases expression multiple interactions |
EXP ISO |
Streptozocin results in increased expression of NCF1 protein telmisartan inhibits the reaction [Streptozocin results in increased expression of NCF1 protein]; terutroban inhibits the reaction [Streptozocin results in increased expression of NCF1 protein] 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of NCF1 mRNA]; 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of NCF1 protein]; [Streptozocin co-treated with Cholesterol, Dietary] results in increased expression of NCF1 protein; Cholesterol, Dietary promotes the reaction [Streptozocin results in increased expression of NCF1 protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Cholesterol, Dietary] results in increased expression of NCF1 protein] Streptozocin results in increased expression of NCF1 mRNA; Streptozocin results in increased expression of NCF1 protein |
CTD |
PMID:14871415 PMID:16380483 PMID:20399799 PMID:21381899 |
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NCBI chr 5:134,248,907...134,258,479
Ensembl chr 5:134,248,907...134,258,479
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G |
Ncf2 |
neutrophil cytosolic factor 2 |
increases expression multiple interactions |
EXP ISO |
Streptozocin results in increased expression of NCF2 protein telmisartan inhibits the reaction [Streptozocin results in increased expression of NCF2 protein] [Carbamazepine affects the susceptibility to [Dietary Fats co-treated with Streptozocin]] which results in decreased expression of NCF2 mRNA |
CTD |
PMID:21381899 PMID:35786680 |
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NCBI chr 1:152,675,904...152,712,743
Ensembl chr 1:152,675,945...152,712,742
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G |
Ndst1 |
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 |
multiple interactions decreases expression |
ISO |
Enalapril inhibits the reaction [Streptozocin results in decreased expression of NDST1 protein]; Losartan inhibits the reaction [Streptozocin results in decreased expression of NDST1 protein] Streptozocin results in decreased expression of NDST1 mRNA; Streptozocin results in decreased expression of NDST1 protein |
CTD |
PMID:15793251 |
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NCBI chr18:60,817,566...60,907,465
Ensembl chr18:60,817,566...60,881,722
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G |
Ndufa10 |
NADH:ubiquinone oxidoreductase subunit A10 |
multiple interactions increases expression |
ISO |
Trientine inhibits the reaction [Streptozocin results in increased expression of NDUFA10 protein] |
CTD |
PMID:21136691 |
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NCBI chr 1:92,367,208...92,401,547
Ensembl chr 1:92,366,732...92,401,582
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G |
Ndufa8 |
NADH:ubiquinone oxidoreductase subunit A8 |
affects expression |
EXP |
Streptozocin affects the expression of NDUFA8 mRNA |
CTD |
PMID:18583417 |
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NCBI chr 2:35,926,336...35,939,350
Ensembl chr 2:35,926,338...35,939,418
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G |
Ndufab1 |
NADH:ubiquinone oxidoreductase subunit AB1 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of NDUFAB1 protein Trientine inhibits the reaction [Streptozocin results in increased expression of NDUFAB1 protein] |
CTD |
PMID:19634143 |
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NCBI chr 7:121,686,038...121,701,071
Ensembl chr 7:121,684,626...121,701,109
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G |
Ndufs2 |
NADH:ubiquinone oxidoreductase core subunit S2 |
multiple interactions increases expression |
ISO |
Trientine inhibits the reaction [Streptozocin results in increased expression of NDUFS2 protein] |
CTD |
PMID:19634143 |
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NCBI chr 1:171,062,426...171,078,956
Ensembl chr 1:171,062,422...171,078,957
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G |
Ndufs4 |
NADH:ubiquinone oxidoreductase core subunit S4 |
multiple interactions increases expression |
ISO |
Trientine inhibits the reaction [Streptozocin results in increased expression of NDUFS4 protein] |
CTD |
PMID:19634143 |
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NCBI chr13:114,424,331...114,524,630
Ensembl chr13:114,424,331...114,524,794
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G |
Ndufs8 |
NADH:ubiquinone oxidoreductase core subunit S8 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of NDUFS8 mRNA; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NDUFS8 mRNA]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NDUFS8 mRNA] |
CTD |
PMID:37337224 |
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NCBI chr19:3,958,863...3,962,774
Ensembl chr19:3,958,863...3,962,774
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G |
Ndufv2 |
NADH:ubiquinone oxidoreductase core subunit V2 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of NDUFV2 protein Trientine inhibits the reaction [Streptozocin results in increased expression of NDUFV2 protein] |
CTD |
PMID:19634143 |
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NCBI chr17:66,385,790...66,408,554
Ensembl chr17:66,385,633...66,408,554
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G |
Nefh |
neurofilament, heavy polypeptide |
decreases expression |
ISO |
Streptozocin results in decreased expression of NEFH protein |
CTD |
PMID:30583000 |
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NCBI chr11:4,888,754...4,898,064
Ensembl chr11:4,888,754...4,898,064
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G |
Nes |
nestin |
multiple interactions decreases expression |
ISO |
INS protein inhibits the reaction [Streptozocin results in decreased expression of NES mRNA] Streptozocin results in decreased expression of NES mRNA; Streptozocin results in decreased expression of NES protein |
CTD |
PMID:19388005 |
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NCBI chr 3:87,878,400...87,887,758
Ensembl chr 3:87,878,385...87,887,758
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G |
Neu2 |
neuraminidase 2 |
increases expression |
ISO |
Streptozocin results in increased expression of NEU2 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 1:87,501,749...87,525,567
Ensembl chr 1:87,437,611...87,525,567
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G |
Neurod1 |
neurogenic differentiation 1 |
multiple interactions decreases expression |
EXP |
[Streptozocin co-treated with bisphenol A] results in decreased expression of NEUROD1 mRNA; octylphenol inhibits the reaction [Streptozocin results in decreased expression of NEUROD1 mRNA]; Streptozocin inhibits the reaction [Ethinyl Estradiol results in increased expression of NEUROD1 mRNA]; Streptozocin inhibits the reaction [octylphenol results in increased expression of NEUROD1 mRNA] |
CTD |
PMID:24781736 PMID:29935216 |
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NCBI chr 2:79,282,981...79,286,980
Ensembl chr 2:79,282,865...79,287,095
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G |
Nfatc1 |
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of NFATC1 mRNA; Streptozocin results in increased expression of NFATC1 protein formononetin inhibits the reaction [Streptozocin results in increased expression of NFATC1 mRNA]; formononetin inhibits the reaction [Streptozocin results in increased expression of NFATC1 protein] |
CTD |
PMID:35315182 |
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NCBI chr18:80,649,418...80,756,286
Ensembl chr18:80,649,420...80,756,286
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G |
Nfe2l2 |
nuclear factor, erythroid derived 2, like 2 |
multiple interactions increases expression affects response to substance decreases expression affects localization increases activity increases expression |
ISO EXP |
2-tert-butylhydroquinone inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of NFE2L2 mRNA]; 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of NFE2L2 protein]; 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of NFE2L2 protein]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of NFE2L2 protein; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of NFE2L2 mRNA; [Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 protein]; [Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of NFE2L2 mRNA; [Streptozocin co-treated with Niacinamide] results in decreased expression of NFE2L2 protein; [Zinc co-treated with Selenium] inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; allyl isothiocyanate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [NFE2L2 protein inhibits the reaction [Streptozocin results in increased expression of USP15 protein]]; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of NFE2L2 mRNA]; chromium histidinate inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; Curcumin inhibits the reaction [Streptozocin affects the localization of NFE2L2 protein]; dapagliflozin inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; diallyl trisulfide inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; Dimethyl Fumarate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; G6PD protein promotes the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; G6PD protein promotes the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of NFE2L2 mRNA]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of NFE2L2 protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of NFE2L2 mRNA]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of NFE2L2 mRNA]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of NFE2L2 mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 protein]; Metformin inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; NFE2L2 protein inhibits the reaction [Streptozocin results in decreased expression of G6PD mRNA]; NFE2L2 protein inhibits the reaction [Streptozocin results in decreased expression of G6PD protein]; NFE2L2 protein inhibits the reaction [Streptozocin results in increased expression of USP15 protein]; palbinone inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; picolinic acid inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; Plant Extracts inhibits the reaction [Streptozocin affects the localization of NFE2L2 protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of NFE2L2 mRNA]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of NFE2L2 protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; Resveratrol promotes the reaction [Streptozocin affects the localization of NFE2L2 protein]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; Streptozocin results in decreased expression of and results in decreased phosphorylation of NFE2L2 protein; STUB1 inhibits the reaction [Streptozocin results in decreased expression of and results in decreased phosphorylation of NFE2L2 protein]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; USP15 protein inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; USP15 protein inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein] Streptozocin results in increased expression of NFE2L2 mRNA; Streptozocin results in increased expression of NFE2L2 protein NFE2L2 protein affects the susceptibility to Streptozocin Streptozocin results in decreased expression of NFE2L2 mRNA; Streptozocin results in decreased expression of NFE2L2 protein 2,5-dihydroxybenzoic acid promotes the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of NFE2L2 protein]; [Acrylamide co-treated with Streptozocin] results in decreased expression of NFE2L2 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of NFE2L2 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of NFE2L2 protein; [NFE2L2 protein mutant form co-treated with Streptozocin] results in increased abundance of 3-Hydroxybutyric Acid; [NFE2L2 protein mutant form co-treated with Streptozocin] results in increased abundance of Glucose; [NFE2L2 protein mutant form co-treated with Streptozocin] results in increased abundance of Triglycerides; [Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 protein; [Streptozocin co-treated with Niacinamide] results in increased expression of NFE2L2 protein; [Streptozocin co-treated with sulforaphane] results in increased expression of NFE2L2; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of NFE2L2 mRNA]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of NFE2L2 protein]; Metformin promotes the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of NFE2L2 protein]; NFE2L2 protein affects the reaction [Streptozocin results in decreased abundance of Glycogen]; pterostilbene inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; pterostilbene inhibits the reaction [Streptozocin results in decreased phosphorylation of and affects the localization of NFE2L2 protein]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 mRNA]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 protein]; Streptozocin results in decreased expression of and results in decreased phosphorylation of NFE2L2 protein; Streptozocin results in decreased phosphorylation of and affects the localization of NFE2L2 protein; sulforaphane inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 mRNA]; sulforaphane inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 protein]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of and results in decreased phosphorylation of NFE2L2 protein]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA] Streptozocin results in increased activity of NFE2L2 protein streptozocin increases expression of Nfe2l2 protein in heart |
CTD RGD |
PMID:20086057 PMID:20399799 PMID:21439372 PMID:21799698 PMID:22023613 PMID:22790776 PMID:23319174 PMID:23453443 PMID:24707343 PMID:24740756 PMID:24967692 PMID:25541178 PMID:26700463 PMID:30203046 PMID:30817903 PMID:30927557 PMID:31173751 PMID:31726037 PMID:32202043 PMID:32233808 PMID:32662907 PMID:33359794 PMID:33639173 PMID:34610774 PMID:34896238 PMID:35442559 PMID:35478295 PMID:36510688 PMID:36999408 PMID:37120126 PMID:37352119 PMID:36044268 More...
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RGD:156430337 |
NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
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G |
Nfkb1 |
nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 |
increases activity multiple interactions |
ISO EXP |
Streptozocin results in increased activity of NFKB1 protein [Dietary Fats co-treated with Streptozocin] results in increased expression of NFKB1 mRNA; [Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NFKB1 protein]; [Streptozocin co-treated with Dietary Fats] results in increased expression of NFKB1 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of NFKB1 protein; Bilirubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NFKB1 mRNA]; Dimethyl Fumarate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NFKB1 protein]; Fungal Polysaccharides inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of NFKB1 mRNA]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NFKB1 protein]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of NFKB1 mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NFKB1 protein] [Streptozocin co-treated with Dietary Fats] results in increased expression of NFKB1 mRNA; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NFKB1 mRNA] |
CTD |
PMID:15284299 PMID:31100278 PMID:34610774 PMID:36999408 PMID:37054934 |
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NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308
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G |
Nfkbia |
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha |
increases expression multiple interactions decreases expression increases phosphorylation increases degradation |
ISO EXP |
Streptozocin results in increased expression of NFKBIA mRNA; Streptozocin results in increased expression of NFKBIA protein arjunolic acid inhibits the reaction [Streptozocin results in decreased expression of NFKBIA protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased phosphorylation of NFKBIA protein]; benazepril inhibits the reaction [Streptozocin results in decreased expression of NFKBIA mRNA]; bisphenol A diglycidyl ether inhibits the reaction [Calcitriol inhibits the reaction [Streptozocin results in decreased expression of NFKBIA protein]]; Calcitriol inhibits the reaction [Streptozocin results in decreased expression of NFKBIA protein]; chromium histidinate inhibits the reaction [Streptozocin results in decreased expression of NFKBIA protein]; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in decreased expression of NFKBIA mRNA]; fasudil inhibits the reaction [Streptozocin results in decreased expression of NFKBIA protein]; IGF2R protein modified form promotes the reaction [Streptozocin results in decreased expression of NFKBIA protein modified form]; picolinic acid inhibits the reaction [Streptozocin results in decreased expression of NFKBIA protein]; Quercetin inhibits the reaction [Streptozocin results in increased degradation of NFKBIA protein]; Streptozocin promotes the reaction [IGF2R protein modified form results in decreased expression of NFKBIA protein modified form]; vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of NFKBIA mRNA] Streptozocin results in decreased expression of NFKBIA mRNA; Streptozocin results in decreased expression of NFKBIA protein; Streptozocin results in decreased expression of NFKBIA protein modified form |
CTD |
PMID:15284299 PMID:15976052 PMID:16177186 PMID:16684804 PMID:17900838 PMID:20053369 PMID:22790776 PMID:23376009 PMID:24781736 PMID:29953732 PMID:36462176 More...
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NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432
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G |
Nfkbib |
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of NFKBIB mRNA; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NFKBIB mRNA] |
CTD |
PMID:34610774 |
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NCBI chr 7:28,457,676...28,466,069
Ensembl chr 7:28,457,676...28,466,937
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G |
Nfkbiz |
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of NFKBIZ mRNA |
CTD |
PMID:25905778 |
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NCBI chr16:55,631,740...55,659,018
Ensembl chr16:55,631,738...55,659,262
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G |
Ngf |
nerve growth factor |
multiple interactions affects localization increases expression decreases expression |
ISO |
4-methylcatechol inhibits the reaction [Streptozocin results in decreased expression of NGF protein]; Butylated Hydroxytoluene inhibits the reaction [Streptozocin results in increased expression of NGF mRNA]; epalrestat inhibits the reaction [Streptozocin results in decreased expression of NGF protein]; sorbinil inhibits the reaction [Streptozocin results in increased expression of NGF mRNA]; Vitamin B 12 inhibits the reaction [Streptozocin results in decreased expression of NGF protein] Streptozocin affects the localization of NGF protein |
CTD |
PMID:8195800 PMID:9628756 PMID:9748608 PMID:12031555 PMID:38049026 |
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NCBI chr 3:102,377,235...102,428,329
Ensembl chr 3:102,377,235...102,428,329
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G |
Nim1k |
NIM1 serine/threonine protein kinase |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in decreased expression of NIM1K mRNA |
CTD |
PMID:25905778 |
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NCBI chr13:120,171,630...120,217,418
Ensembl chr13:120,171,630...120,217,418
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G |
Nipsnap2 |
nipsnap homolog 2 |
affects expression |
EXP |
Streptozocin affects the expression of NIPSNAP2 mRNA |
CTD |
PMID:18583417 |
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NCBI chr 5:129,802,080...129,835,391
Ensembl chr 5:129,802,127...129,835,391
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G |
Nkap |
NFKB activating protein |
multiple interactions |
ISO |
Streptozocin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of NKAP mRNA] |
CTD |
PMID:30611788 |
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NCBI chr X:36,390,416...36,414,399
Ensembl chr X:36,390,448...36,414,399
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G |
Nlrp3 |
NLR family, pyrin domain containing 3 |
multiple interactions increases expression |
ISO EXP |
[Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NLRP3 protein]; [Streptozocin co-treated with Dietary Fats] results in increased expression of NLRP3 protein; Allopurinol inhibits the reaction [Streptozocin results in increased expression of NLRP3 mRNA]; Allopurinol inhibits the reaction [Streptozocin results in increased expression of NLRP3 protein]; Dimethyl Fumarate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NLRP3 protein]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NLRP3 protein]; myrtenol inhibits the reaction [Streptozocin results in increased expression of NLRP3 mRNA]; palbinone inhibits the reaction [Streptozocin results in increased expression of NLRP3 protein]; Quercetin inhibits the reaction [Streptozocin results in increased expression of NLRP3 mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of NLRP3 protein]; scutellarin inhibits the reaction [Streptozocin results in increased expression of NLRP3 protein] Streptozocin results in increased expression of NLRP3 mRNA; Streptozocin results in increased expression of NLRP3 protein [Dietary Fats co-treated with Streptozocin] results in increased expression of NLRP3 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of NLRP3 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of NLRP3 protein; aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NLRP3 protein]; loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of NLRP3 mRNA]; loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of NLRP3 protein]; NLRP3 protein promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of TJP1 protein]; NLRP3 protein promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of TJP2 protein]; NLRP3 protein promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased activity of CASP1 protein] |
CTD |
PMID:23647015 PMID:27783111 PMID:32202043 PMID:34477272 PMID:35961541 PMID:36999408 PMID:37081038 PMID:37473909 More...
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NCBI chr11:59,432,395...59,457,781
Ensembl chr11:59,432,394...59,457,782
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G |
Nmrk1 |
nicotinamide riboside kinase 1 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of NMRK1 mRNA [resveratrol co-treated with Streptozocin] results in decreased expression of NMRK1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr19:18,609,380...18,629,555
Ensembl chr19:18,609,314...18,629,792
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G |
Nnt |
nicotinamide nucleotide transhydrogenase |
multiple interactions increases expression |
ISO |
Trientine inhibits the reaction [Streptozocin results in increased expression of NNT protein] |
CTD |
PMID:19634143 |
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NCBI chr13:119,472,063...119,545,793
Ensembl chr13:119,471,984...119,545,533 Ensembl chr13:119,471,984...119,545,533
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G |
Nos1 |
nitric oxide synthase 1, neuronal |
multiple interactions decreases expression increases expression |
ISO EXP |
1-hexacosanol inhibits the reaction [Streptozocin results in decreased expression of NOS1 mRNA]; 1-hexacosanol inhibits the reaction [Streptozocin results in decreased expression of NOS1 protein]; [Sildenafil Citrate co-treated with resveratrol] inhibits the reaction [Streptozocin results in decreased expression of NOS1 protein]; resveratrol inhibits the reaction [Streptozocin results in decreased expression of NOS1 protein] Streptozocin results in decreased expression of NOS1 mRNA; Streptozocin results in decreased expression of NOS1 protein Streptozocin results in increased expression of NOS1 mRNA Acrylamide inhibits the reaction [Streptozocin results in increased expression of NOS1 mRNA] |
CTD |
PMID:18528636 PMID:26006044 PMID:34896238 |
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NCBI chr 5:118,004,904...118,096,905
Ensembl chr 5:117,919,097...118,096,905
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G |
Nos2 |
nitric oxide synthase 2, inducible |
multiple interactions increases activity increases expression |
EXP ISO |
[bisphenol A co-treated with Streptozocin] results in decreased expression of NOS2 protein; [Ethinyl Estradiol co-treated with Streptozocin] results in decreased expression of NOS2 protein; [octylphenol co-treated with Streptozocin] results in decreased expression of NOS2 protein; [Streptozocin co-treated with bisphenol A] results in increased expression of NOS2 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of NOS2 mRNA; AM6545 inhibits the reaction [Streptozocin results in increased expression of NOS2 mRNA]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in increased expression of NOS2 mRNA]]; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NOS2 mRNA]; Perindopril inhibits the reaction [Streptozocin results in increased expression of NOS2 mRNA]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in increased expression of NOS2 mRNA]]; Quercetin inhibits the reaction [Streptozocin results in increased expression of NOS2 protein]; Sodium Selenite inhibits the reaction [Streptozocin results in increased activity of NOS2 protein]; Sodium Selenite inhibits the reaction [Streptozocin results in increased expression of NOS2 mRNA]; Streptozocin inhibits the reaction [Ethinyl Estradiol results in decreased expression of NOS2 mRNA]; Streptozocin inhibits the reaction [octylphenol results in decreased expression of NOS2 mRNA]; terutroban inhibits the reaction [Streptozocin results in increased expression of NOS2 protein] Streptozocin results in increased expression of NOS2 mRNA; Streptozocin results in increased expression of NOS2 protein 1-hexacosanol inhibits the reaction [Streptozocin results in increased expression of NOS2 mRNA]; 1-hexacosanol inhibits the reaction [Streptozocin results in increased expression of NOS2 protein]; [Ascorbic Acid co-treated with Vitamin E co-treated with beta Carotene co-treated with Copper] inhibits the reaction [Streptozocin results in increased expression of NOS2 mRNA]; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of NOS2 mRNA; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of NOS2 mRNA]; candesartan inhibits the reaction [Streptozocin results in increased expression of NOS2 protein]; cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in increased expression of NOS2 protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of NOS2 protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased activity of NOS2 protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of NOS2 mRNA]; Kangen-karyu inhibits the reaction [Streptozocin results in increased expression of NOS2 protein]; Metformin inhibits the reaction [Streptozocin results in increased activity of NOS2 protein]; Metoprolol inhibits the reaction [Streptozocin results in increased expression of NOS2 protein]; Plant Extracts inhibits the reaction [Streptozocin results in increased expression of NOS2 mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of NOS2 protein]; tin mesoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in increased expression of NOS2 protein]]; Triterpenes inhibits the reaction [Streptozocin results in increased activity of NOS2 protein]; Triterpenes inhibits the reaction [Streptozocin results in increased expression of NOS2 mRNA] |
CTD |
PMID:15821039 PMID:16139267 PMID:16177186 PMID:16309587 PMID:16380483 PMID:18528636 PMID:18703049 PMID:18779489 PMID:18789669 PMID:19000375 PMID:19397970 PMID:19957251 PMID:22675305 PMID:25541178 PMID:25635252 PMID:26690102 PMID:26887929 PMID:29935216 PMID:30184259 PMID:33484791 PMID:33639173 PMID:36510688 More...
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NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
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G |
Nos3 |
nitric oxide synthase 3, endothelial cell |
multiple interactions increases expression decreases phosphorylation decreases expression |
ISO |
1,3-dimethoxy-5-methyl-2-(3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl)benzene inhibits the reaction [4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in decreased phosphorylation of NOS3 protein]]; 1-hexacosanol inhibits the reaction [Streptozocin results in decreased expression of NOS3 protein]; 4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in decreased phosphorylation of NOS3 protein]; [Sildenafil Citrate co-treated with Resveratrol] inhibits the reaction [Streptozocin results in decreased expression of NOS3 protein]; [Streptozocin co-treated with Dietary Fats] results in decreased expression of NOS3 mRNA; Acetylcysteine inhibits the reaction [Streptozocin results in decreased phosphorylation of NOS3 protein]; Allopurinol inhibits the reaction [Streptozocin results in decreased phosphorylation of NOS3 protein]; Allopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased phosphorylation of NOS3 protein]]; Atorvastatin inhibits the reaction [Streptozocin results in decreased expression of NOS3 protein]; candesartan inhibits the reaction [Streptozocin results in increased expression of NOS3 mRNA]; candesartan inhibits the reaction [Streptozocin results in increased expression of NOS3 protein]; Cholesterol, Dietary inhibits the reaction [Streptozocin results in increased expression of NOS3 protein]; cloricromen inhibits the reaction [Streptozocin results in increased expression of NOS3 protein]; cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased phosphorylation of NOS3 protein]; esculetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NOS3 mRNA]; Resveratrol inhibits the reaction [Streptozocin promotes the reaction [CAV1 protein binds to NOS3 protein]]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of NOS3 mRNA]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of NOS3 protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased phosphorylation of NOS3 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of NOS3 mRNA]; Streptozocin promotes the reaction [CAV1 protein binds to NOS3 protein]; Streptozocin results in decreased activity of and results in decreased phosphorylation of NOS3 protein Streptozocin results in increased expression of NOS3 mRNA; Streptozocin results in increased expression of NOS3 protein Streptozocin results in decreased expression of NOS3 mRNA; Streptozocin results in decreased expression of NOS3 protein |
CTD |
PMID:11696579 PMID:12377873 PMID:14871415 PMID:16045816 PMID:16139267 PMID:17589825 PMID:18266981 PMID:18528636 PMID:18703049 PMID:19279317 PMID:21664865 PMID:21912612 PMID:22191573 PMID:22675305 PMID:26006044 PMID:26071184 PMID:28946194 PMID:29274332 More...
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NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472
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G |
Nox4 |
NADPH oxidase 4 |
multiple interactions increases expression |
ISO EXP |
[Resveratrol co-treated with Streptozocin] results in decreased expression of NOX4 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of NOX4 protein; Bezafibrate inhibits the reaction [Streptozocin results in increased expression of NOX4 mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NOX4 protein]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of NOX4 mRNA] [Streptozocin co-treated with Dietary Fats] results in decreased expression of NOX4 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of NOX4 protein; aucubin inhibits the reaction [Streptozocin results in increased expression of NOX4 protein] |
CTD |
PMID:16979161 PMID:25905778 PMID:29127188 PMID:35085591 PMID:35961541 |
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NCBI chr 7:86,893,638...87,047,918
Ensembl chr 7:86,895,304...87,047,918
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G |
Npas2 |
neuronal PAS domain protein 2 |
decreases expression |
ISO |
Streptozocin results in decreased expression of NPAS2 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 1:39,233,013...39,402,321
Ensembl chr 1:39,232,812...39,402,317
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G |
Nphs1 |
nephrosis 1, nephrin |
decreases expression |
ISO EXP |
Streptozotocin decreases expression of Nphs1 mRNA and protein in kidney Streptozotocin decreases expression of Nphs1 mRNA and protein in renal glomerulus Streptozocin decreases expression of Nphs1 mRNA in kidney streptozotocin decreases expression of Nphs1 protein in kidney |
RGD |
PMID:17624267 PMID:30862474 PMID:24173355 PMID:21617141 |
RGD:38596322, RGD:38596325, RGD:38599008, RGD:7241083 |
NCBI chr 7:30,157,259...30,188,048
Ensembl chr 7:30,157,740...30,186,648
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G |
Nphs2 |
nephrosis 2, podocin |
multiple interactions decreases expression |
ISO EXP |
Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in decreased expression of NPHS2 mRNA]; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in decreased expression of NPHS2 protein]; procyanidin B2 inhibits the reaction [Streptozocin results in increased expression of NPHS2 mRNA]; procyanidin B2 inhibits the reaction [Streptozocin results in increased expression of NPHS2 protein] Streptozocin results in decreased expression of NPHS2 mRNA; Streptozocin results in decreased expression of NPHS2 protein AM6545 inhibits the reaction [Streptozocin results in decreased expression of NPHS2 mRNA]; AM6545 inhibits the reaction [Streptozocin results in decreased expression of NPHS2 protein]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in decreased expression of NPHS2 mRNA]]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in decreased expression of NPHS2 protein]]; Perindopril inhibits the reaction [Streptozocin results in decreased expression of NPHS2 mRNA]; Perindopril inhibits the reaction [Streptozocin results in decreased expression of NPHS2 protein]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in decreased expression of NPHS2 mRNA]]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in decreased expression of NPHS2 protein]] |
CTD |
PMID:20547220 PMID:25199697 PMID:30184259 |
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NCBI chr 1:156,138,105...156,155,605
Ensembl chr 1:156,138,297...156,155,605
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G |
Nppa |
natriuretic peptide type A |
increases expression multiple interactions |
ISO EXP |
Streptozocin results in increased expression of NPPA mRNA; Streptozocin results in increased expression of NPPA protein SLC25A4 protein inhibits the reaction [Streptozocin results in increased expression of NPPA mRNA] Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in increased expression of NPPA protein] |
CTD |
PMID:16409969 PMID:16980342 PMID:18945756 |
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NCBI chr 4:148,085,179...148,086,531
Ensembl chr 4:148,085,179...148,086,536
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G |
Nppb |
natriuretic peptide type B |
increases expression multiple interactions |
ISO EXP |
Streptozocin results in increased expression of NPPB mRNA [Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of NPPB protein; Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of NPPB protein] [Streptozocin co-treated with Dietary Fats] results in increased expression of NPPB protein; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NPPB protein] |
CTD |
PMID:10828832 PMID:34610774 PMID:34801538 |
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NCBI chr 4:148,070,264...148,071,662
Ensembl chr 4:148,070,245...148,071,662
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G |
Nppc |
natriuretic peptide type C |
decreases expression |
ISO |
Streptozocin results in decreased expression of NPPC mRNA |
CTD |
PMID:10828832 |
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NCBI chr 1:86,594,015...86,598,295
Ensembl chr 1:86,594,013...86,598,293
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G |
Npy |
neuropeptide Y |
multiple interactions increases expression |
ISO |
INS protein inhibits the reaction [Streptozocin results in increased expression of NPY mRNA] |
CTD |
PMID:20219977 |
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NCBI chr 6:49,799,690...49,806,487
Ensembl chr 6:49,799,690...49,806,487
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G |
Nqo1 |
NAD(P)H dehydrogenase, quinone 1 |
multiple interactions decreases expression affects response to substance increases expression |
ISO EXP |
diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of NQO1 mRNA]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of NQO1 protein]; Metformin inhibits the reaction [Streptozocin results in decreased expression of NQO1 mRNA]; Metformin inhibits the reaction [Streptozocin results in decreased expression of NQO1 protein]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of NQO1 mRNA] Streptozocin results in decreased expression of NQO1 mRNA; Streptozocin results in decreased expression of NQO1 protein NQO1 protein affects the susceptibility to Streptozocin Streptozocin results in increased expression of NQO1 mRNA 2,5-dihydroxybenzoic acid promotes the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of NQO1 mRNA]; [omaveloxolone analog co-treated with Streptozocin co-treated with Dietary Fats] results in increased activity of NQO1 protein; [omaveloxolone co-treated with Streptozocin co-treated with Dietary Fats] results in increased activity of NQO1 protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of NQO1 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of NQO1 mRNA; [Streptozocin co-treated with Niacinamide] results in increased expression of NQO1 mRNA; [Streptozocin co-treated with NQO1 protein mutant form] results in increased expression of AIFM1 protein; [Streptozocin co-treated with NQO1 protein mutant form] results in increased expression of CASP3 protein modified form; [Streptozocin co-treated with NQO1 protein mutant form] results in increased secretion of DIABLO protein; [Streptozocin co-treated with sulforaphane] results in increased expression of NQO1; Metformin promotes the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of NQO1 mRNA]; omaveloxolone analog promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NQO1 mRNA]; omaveloxolone promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NQO1 mRNA]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NQO1 mRNA]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of NQO1 mRNA]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of NQO1 protein] |
CTD |
PMID:21457706 PMID:22023613 PMID:22531820 PMID:23319174 PMID:23458895 PMID:24967692 PMID:32410268 PMID:32662907 PMID:33639173 PMID:34610774 PMID:37120126 More...
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NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838
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G |
Nr0b2 |
nuclear receptor subfamily 0, group B, member 2 |
multiple interactions |
ISO EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of NR0B2 mRNA [Dietary Fats co-treated with Streptozocin] results in increased expression of NR0B2 protein |
CTD |
PMID:25905778 PMID:29382564 |
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NCBI chr 4:133,280,687...133,283,997
Ensembl chr 4:133,280,687...133,283,847
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G |
Nr1d1 |
nuclear receptor subfamily 1, group D, member 1 |
decreases expression |
ISO |
Streptozocin results in decreased expression of NR1D1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr11:98,658,758...98,666,233
Ensembl chr11:98,658,758...98,666,159
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G |
Nr1h2 |
nuclear receptor subfamily 1, group H, member 2 |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of NR1H2 protein [homocastasterone analog co-treated with Streptozocin] results in increased expression of NR1H2 mRNA; homocastasterone analog inhibits the reaction [Streptozocin results in decreased expression of NR1H2 protein] |
CTD |
PMID:28822685 |
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NCBI chr 7:44,199,040...44,204,928
Ensembl chr 7:44,199,040...44,203,375
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G |
Nr1h3 |
nuclear receptor subfamily 1, group H, member 3 |
multiple interactions increases expression |
ISO |
[homocastasterone analog co-treated with Streptozocin] results in increased expression of NR1H3 mRNA; [homocastasterone analog co-treated with Streptozocin] results in increased expression of NR1H3 protein; Allopurinol inhibits the reaction [Streptozocin results in increased expression of NR1H3 mRNA]; Allopurinol inhibits the reaction [Streptozocin results in increased expression of NR1H3 protein]; Quercetin inhibits the reaction [Streptozocin results in increased expression of NR1H3 mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of NR1H3 protein] Streptozocin results in increased expression of NR1H3 mRNA; Streptozocin results in increased expression of NR1H3 protein |
CTD |
PMID:23647015 PMID:28822685 |
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NCBI chr 2:91,014,406...91,033,189
Ensembl chr 2:91,014,406...91,033,179
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G |
Nr1h4 |
nuclear receptor subfamily 1, group H, member 4 |
multiple interactions |
EXP |
[Dietary Fats co-treated with Streptozocin] results in decreased expression of NR1H4 protein |
CTD |
PMID:29382564 |
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NCBI chr10:89,290,096...89,369,484
Ensembl chr10:89,290,096...89,369,447
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G |
Nr5a1 |
nuclear receptor subfamily 5, group A, member 1 |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of NR5A1 mRNA; Streptozocin results in decreased expression of NR5A1 protein carvacrol affects the reaction [Streptozocin results in decreased expression of NR5A1 mRNA]; carvacrol affects the reaction [Streptozocin results in decreased expression of NR5A1 protein] |
CTD |
PMID:32153207 |
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NCBI chr 2:38,582,668...38,604,554
Ensembl chr 2:38,582,668...38,604,554
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G |
Nt5e |
5' nucleotidase, ecto |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of NT5E mRNA |
CTD |
PMID:29127188 |
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NCBI chr 9:88,209,662...88,254,142
Ensembl chr 9:88,209,250...88,254,145
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G |
Ntf3 |
neurotrophin 3 |
affects localization |
ISO |
Streptozocin affects the localization of NTF3 protein |
CTD |
PMID:12031555 |
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NCBI chr 6:126,078,375...126,143,703
Ensembl chr 6:126,078,375...126,143,873
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G |
Ntn1 |
netrin 1 |
decreases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of NTN1 protein [NTN1 protein co-treated with Streptozocin] results in increased expression of ARG1 protein; NTN1 protein inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; NTN1 protein inhibits the reaction [Streptozocin results in increased expression of CDKN2A mRNA]; NTN1 protein inhibits the reaction [Streptozocin results in increased expression of CDKN2A protein]; NTN1 protein inhibits the reaction [Streptozocin results in increased expression of PTGS2 protein]; NTN1 protein inhibits the reaction [Streptozocin results in increased expression of RELA protein]; NTN1 protein inhibits the reaction [Streptozocin results in increased expression of TRP53 mRNA]; NTN1 protein promotes the reaction [Streptozocin results in increased expression of DCC mRNA]; NTN1 protein promotes the reaction [Streptozocin results in increased expression of DCC protein]; Streptozocin promotes the reaction [NTN1 protein results in increased phosphorylation of MAPK1 protein]; Streptozocin promotes the reaction [NTN1 protein results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:29059224 |
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NCBI chr11:68,100,190...68,277,652
Ensembl chr11:68,100,190...68,291,649
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G |
Ntrk1 |
neurotrophic tyrosine kinase, receptor, type 1 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of NTRK1 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of NTRK1 mRNA; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NTRK1 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 3:87,685,551...87,702,549
Ensembl chr 3:87,685,551...87,702,469
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G |
Ntrk2 |
neurotrophic tyrosine kinase, receptor, type 2 |
multiple interactions decreases phosphorylation decreases expression |
EXP ISO |
Acetylcysteine inhibits the reaction [Streptozocin results in decreased phosphorylation of NTRK2 protein]; Physostigmine inhibits the reaction [Streptozocin results in decreased phosphorylation of NTRK2 protein] Metformin inhibits the reaction [Streptozocin results in increased expression of NTRK2 mRNA]; morin inhibits the reaction [Streptozocin results in increased expression of NTRK2 mRNA] Streptozocin results in decreased expression of NTRK2 mRNA |
CTD |
PMID:28499986 PMID:35414346 |
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NCBI chr13:58,954,363...59,281,782
Ensembl chr13:58,954,383...59,281,784
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G |
Nudt7 |
nudix hydrolase 7 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of NUDT7 mRNA |
CTD |
PMID:29127188 |
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NCBI chr 8:114,860,314...114,881,471
Ensembl chr 8:114,860,297...114,881,479
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G |
Nus1 |
NUS1 dehydrodolichyl diphosphate synthase subunit |
multiple interactions |
EXP |
[Dietary Fats co-treated with Streptozocin] results in decreased expression of NUS1 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of NUS1 protein; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of MFN2 mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PPARGC1A mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SIRT1 mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of GSK3B protein]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of ACACA mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of ATF4 mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of ATF6 mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of DGAT1 mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of EIF2AK3 protein]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FASN mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GK mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of HSPA5 mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of HSPA5 protein]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of INPP5K mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SREBF1 mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased phosphorylation of EIF2S1 protein]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased splicing of XBP1 mRNA] |
CTD |
PMID:33812996 |
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NCBI chr10:52,293,643...52,316,288
Ensembl chr10:52,293,643...52,316,279
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G |
Nyap1 |
neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of NYAP1 mRNA |
CTD |
PMID:33484791 |
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NCBI chr 5:137,729,144...137,739,430
Ensembl chr 5:137,728,161...137,739,869
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G |
Oat |
ornithine aminotransferase |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of OAT protein Trientine inhibits the reaction [Streptozocin results in decreased expression of OAT protein] |
CTD |
PMID:19634143 |
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NCBI chr 7:132,159,204...132,178,127
Ensembl chr 7:132,159,207...132,178,127
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G |
Ocln |
occludin |
decreases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of OCLN protein rhodioloside inhibits the reaction [Streptozocin results in decreased expression of OCLN protein] |
CTD |
PMID:31682803 |
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NCBI chr13:100,633,012...100,689,226
Ensembl chr13:100,633,015...100,689,226
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G |
Oga |
O-GlcNAcase |
multiple interactions |
ISO |
Streptozocin binds to and results in decreased activity of OGA protein [Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of OGA protein; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of OGA protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of OGA protein] |
CTD |
PMID:18721751 PMID:30551545 |
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NCBI chr19:45,738,698...45,772,274
Ensembl chr19:45,738,698...45,772,276
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G |
Ogdh |
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) |
multiple interactions increases expression |
ISO |
Trientine inhibits the reaction [Streptozocin results in increased expression of OGDH protein] |
CTD |
PMID:19634143 |
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NCBI chr11:6,241,597...6,309,094
Ensembl chr11:6,241,633...6,306,642
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G |
Opn4 |
opsin 4 (melanopsin) |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of OPN4 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of OPN4 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr14:34,312,575...34,322,099
Ensembl chr14:34,312,575...34,322,099
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G |
Or51e2 |
olfactory receptor family 51 subfamily E member 2 |
decreases expression |
ISO |
Streptozocin results in decreased expression of OLR59 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 7:102,389,928...102,408,678
Ensembl chr 7:102,387,718...102,408,678
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G |
Orm1 |
orosomucoid 1 |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of ORM1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 4:63,262,793...63,266,400
Ensembl chr 4:63,262,797...63,266,400
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G |
Orm2 |
orosomucoid 2 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of ORM2 mRNA; Diethylhexyl Phthalate affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of ORM2 mRNA]; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of ORM2 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 4:63,280,543...63,284,114
Ensembl chr 4:63,280,686...63,284,115
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G |
P2rx2 |
purinergic receptor P2X, ligand-gated ion channel, 2 |
increases expression |
EXP |
Streptozocin results in increased expression of P2RX2 mRNA |
CTD |
PMID:19383439 |
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NCBI chr 5:110,487,678...110,491,186
Ensembl chr 5:110,487,678...110,491,078
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G |
P2rx3 |
purinergic receptor P2X, ligand-gated ion channel, 3 |
increases expression |
EXP |
Streptozocin results in increased expression of P2RX3 mRNA |
CTD |
PMID:19383439 |
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NCBI chr 2:84,826,893...84,867,446
Ensembl chr 2:84,828,927...84,867,806
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G |
Pabpc1l |
poly(A) binding protein, cytoplasmic 1-like |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of PABPC1L mRNA |
CTD |
PMID:33484791 |
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NCBI chr 2:163,866,685...163,892,458
Ensembl chr 2:163,867,370...163,892,458
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G |
Pah |
phenylalanine hydroxylase |
multiple interactions increases activity increases expression |
ISO |
peroxovanadate inhibits the reaction [Streptozocin results in increased activity of PAH protein]; peroxovanadate inhibits the reaction [Streptozocin results in increased expression of PAH mRNA] |
CTD |
PMID:11055810 |
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NCBI chr10:87,357,657...87,419,999
Ensembl chr10:87,357,657...87,419,998
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G |
Pak1 |
p21 (RAC1) activated kinase 1 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of PAK1 mRNA |
CTD |
PMID:29127188 |
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NCBI chr 7:97,437,748...97,561,588
Ensembl chr 7:97,437,748...97,561,588
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G |
Parg |
poly (ADP-ribose) glycohydrolase |
increases response to substance |
EXP |
PARG gene mutant form results in increased susceptibility to Streptozocin |
CTD |
PMID:15282315 |
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NCBI chr14:31,923,900...32,020,671
Ensembl chr14:31,923,906...32,019,507
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G |
Parp1 |
poly (ADP-ribose) polymerase family, member 1 |
increases cleavage multiple interactions increases activity |
ISO EXP |
Streptozocin results in increased cleavage of PARP1 protein Anthocyanins inhibits the reaction [Streptozocin results in increased cleavage of PARP1 protein]; Curcumin inhibits the reaction [Streptozocin results in increased cleavage of PARP1 protein] Streptozocin results in increased activity of PARP1 protein [Streptozocin co-treated with Dietary Fats] results in increased expression of PARP1 mRNA; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Streptozocin results in increased activity of PARP1 protein]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of PARP1 mRNA]; SIRT1 protein inhibits the reaction [Streptozocin promotes the reaction [JUN protein binds to PARP1 protein]]; SIRT1 protein inhibits the reaction [Streptozocin promotes the reaction [PARP1 protein binds to MMP9 promoter]]; SIRT1 protein inhibits the reaction [Streptozocin promotes the reaction [RELA protein binds to PARP1 protein]]; Streptozocin promotes the reaction [JUN protein binds to PARP1 protein]; Streptozocin promotes the reaction [PARP1 protein binds to MMP9 promoter]; Streptozocin promotes the reaction [RELA protein binds to PARP1 protein] |
CTD |
PMID:25541178 PMID:27288104 PMID:28478229 PMID:28856781 PMID:34610774 |
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NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
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G |
Pax8 |
paired box 8 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of PAX8 mRNA; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of PAX8 mRNA] |
CTD |
PMID:32303808 |
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NCBI chr 2:24,310,563...24,365,611
Ensembl chr 2:24,310,572...24,365,611
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G |
Pck1 |
phosphoenolpyruvate carboxykinase 1, cytosolic |
multiple interactions increases expression |
ISO EXP |
bis(maltolato)oxovanadium(IV) inhibits the reaction [Streptozocin results in increased expression of PCK1 mRNA]; cinnamaldehyde inhibits the reaction [Streptozocin results in increased expression of PCK1 mRNA]; Glyburide inhibits the reaction [Streptozocin results in increased expression of PCK1 mRNA]; Trientine inhibits the reaction [Streptozocin results in increased expression of PCK1 protein] Streptozocin results in increased expression of PCK1 mRNA; Streptozocin results in increased expression of PCK1 protein [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of PCK1 protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of PCK1 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of PCK1 mRNA; Acrylamide inhibits the reaction [Streptozocin results in increased expression of PCK1 mRNA]; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of PCK1 mRNA] |
CTD |
PMID:12446591 PMID:19634143 PMID:20363216 PMID:25446853 PMID:26522834 PMID:34896238 More...
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NCBI chr 2:172,994,866...173,001,067
Ensembl chr 2:172,994,841...173,001,066
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G |
Pck2 |
phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
increases expression multiple interactions |
ISO EXP |
Streptozocin results in increased expression of PCK2 protein Tribulus extract inhibits the reaction [Streptozocin results in increased expression of PCK2 protein] [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of PCK2 protein; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of PCK2 protein] |
CTD |
PMID:36627075 PMID:39047806 |
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NCBI chr14:55,777,721...55,787,477
Ensembl chr14:55,777,723...55,788,699
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G |
Pcna |
proliferating cell nuclear antigen |
multiple interactions |
ISO EXP |
[Streptozocin co-treated with Tobacco Smoke Pollution] results in increased expression of PCNA protein [Streptozocin co-treated with Dextran Sulfate] results in increased expression of PCNA protein |
CTD |
PMID:30421503 PMID:34964214 |
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NCBI chr 2:132,091,206...132,095,100
Ensembl chr 2:132,091,082...132,095,234
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G |
Pcsk1 |
proprotein convertase subtilisin/kexin type 1 |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of PCSK1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr13:75,237,407...75,282,980
Ensembl chr13:75,237,945...75,282,980
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G |
Pcx |
pyruvate carboxylase |
increases expression multiple interactions |
ISO EXP |
Streptozocin results in increased expression of PC protein Trientine inhibits the reaction [Streptozocin results in increased expression of PC protein] [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of PCX protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of PCX protein |
CTD |
PMID:19634143 PMID:25446853 |
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NCBI chr19:4,560,500...4,671,780
Ensembl chr19:4,560,500...4,671,780
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G |
Pde4b |
phosphodiesterase 4B, cAMP specific |
decreases expression |
ISO |
Streptozocin results in decreased expression of PDE4B mRNA |
CTD |
PMID:25905778 |
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NCBI chr 4:101,944,529...102,464,459
Ensembl chr 4:101,944,740...102,464,456
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G |
Pde5a |
phosphodiesterase 5A, cGMP-specific |
multiple interactions increases expression |
ISO |
[Sildenafil Citrate co-treated with Resveratrol] inhibits the reaction [Streptozocin results in increased expression of PDE5A protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of PDE5A protein] Streptozocin results in increased expression of PDE5A mRNA; Streptozocin results in increased expression of PDE5A protein |
CTD |
PMID:26006044 |
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NCBI chr 3:122,522,822...122,653,023
Ensembl chr 3:122,522,596...122,653,023
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G |
Pde6c |
phosphodiesterase 6C, cGMP specific, cone, alpha prime |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of PDE6C mRNA |
CTD |
PMID:33484791 |
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NCBI chr19:38,121,220...38,172,391
Ensembl chr19:38,121,229...38,172,406
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G |
Pdgfra |
platelet derived growth factor receptor, alpha polypeptide |
decreases expression |
EXP |
Streptozocin results in decreased expression of PDGFRA mRNA |
CTD |
PMID:26073000 |
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NCBI chr 5:75,311,988...75,358,867
Ensembl chr 5:75,312,953...75,358,876
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G |
Pdgfrl |
platelet-derived growth factor receptor-like |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of PDGFRL mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PDGFRL mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 8:41,379,270...41,443,819
Ensembl chr 8:41,379,249...41,443,822
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G |
Pdk1 |
pyruvate dehydrogenase kinase, isoenzyme 1 |
multiple interactions |
EXP |
[1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of PDK1 mRNA]; [Dietary Fats co-treated with Streptozocin] results in increased expression of PDK1 mRNA |
CTD |
PMID:25446853 |
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NCBI chr 2:71,703,398...71,734,202
Ensembl chr 2:71,703,568...71,734,202
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G |
Pdx1 |
pancreatic and duodenal homeobox 1 |
decreases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of PDX1 mRNA [Dietary Fats co-treated with Streptozocin] results in decreased expression of PDX1 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of PDX1 protein; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PDX1 mRNA]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PDX1 protein]; octylphenol inhibits the reaction [Streptozocin results in decreased expression of PDX1 mRNA] |
CTD |
PMID:24781736 PMID:29935216 PMID:33359794 |
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NCBI chr 5:147,206,907...147,212,658
Ensembl chr 5:147,206,769...147,212,658
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G |
Pdxp |
pyridoxal (pyridoxine, vitamin B6) phosphatase |
multiple interactions increases expression |
ISO |
[resveratrol co-treated with Streptozocin] results in decreased expression of PDXP mRNA Streptozocin results in increased expression of PDXP mRNA |
CTD |
PMID:25905778 |
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NCBI chr15:78,796,342...78,803,717
Ensembl chr15:78,798,119...78,803,717
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G |
Pecam1 |
platelet/endothelial cell adhesion molecule 1 |
multiple interactions |
EXP |
[Dietary Fats co-treated with Streptozocin] results in increased expression of PECAM1 protein; Rosuvastatin Calcium inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of PECAM1 protein]; sarpogrelate inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of PECAM1 protein] |
CTD |
PMID:27097221 |
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NCBI chr11:106,545,039...106,606,107
Ensembl chr11:106,545,043...106,641,454
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G |
Pemt |
phosphatidylethanolamine N-methyltransferase |
increases activity affects expression |
ISO EXP |
Streptozocin results in increased activity of PEMT protein Streptozocin affects the expression of PEMT mRNA |
CTD |
PMID:16835399 PMID:18583417 |
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NCBI chr11:59,861,440...59,937,394
Ensembl chr11:59,861,440...59,937,315
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G |
Pfkfb1 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 |
increases expression |
ISO |
Streptozocin results in increased expression of PFKFB1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr X:149,370,441...149,426,874
Ensembl chr X:149,371,225...149,426,874
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G |
Pfkfb2 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 |
decreases activity multiple interactions |
ISO |
Streptozocin results in decreased activity of PFKFB2 protein Lithium Carbonate inhibits the reaction [Streptozocin results in decreased activity of PFKFB2 protein] |
CTD |
PMID:10700396 |
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NCBI chr 1:130,616,780...130,656,990
Ensembl chr 1:130,616,919...130,656,990 Ensembl chr 1:130,616,919...130,656,990
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G |
Pfkp |
phosphofructokinase, platelet |
multiple interactions |
EXP |
[1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PFKP protein]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of PFKP protein |
CTD |
PMID:25446853 |
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NCBI chr13:6,629,910...6,699,096
Ensembl chr13:6,629,804...6,698,813
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G |
Phactr3 |
phosphatase and actin regulator 3 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of PHACTR3 mRNA |
CTD |
PMID:33484791 |
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NCBI chr 2:177,760,768...177,980,285
Ensembl chr 2:177,760,768...177,980,285
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G |
Phb1 |
prohibitin 1 |
decreases expression |
ISO |
Streptozocin results in decreased expression of PHB1 protein |
CTD |
PMID:21136691 |
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NCBI chr11:95,557,783...95,571,599
Ensembl chr11:95,557,783...95,571,599
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G |
Pik3ca |
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha |
multiple interactions |
EXP |
streptozocin decreases expression and increases phosphorylation of Pik3ca in cardiac muscle cells |
RGD |
PMID:36044268 |
RGD:156430337 |
NCBI chr 3:32,451,203...32,520,256
Ensembl chr 3:32,451,820...32,522,635
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G |
Pik3cb |
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta |
decreases expression multiple interactions |
ISO EXP |
Streptozocin results in decreased expression of PIK3CB mRNA resveratrol inhibits the reaction [Streptozocin results in decreased expression of PIK3CB mRNA] [Streptozocin co-treated with Dietary Fats] results in decreased expression of PIK3CB protein; Dibutyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PIK3CB protein]; L 783281 inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PIK3CB protein]; L 783281 inhibits the reaction [Dibutyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PIK3CB protein]] |
CTD |
PMID:26071184 PMID:29526571 |
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NCBI chr 9:98,920,455...99,022,264
Ensembl chr 9:98,918,707...99,022,674
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G |
Pik3r1 |
phosphoinositide-3-kinase regulatory subunit 1 |
decreases expression multiple interactions |
ISO EXP |
Streptozocin results in decreased expression of PIK3R1 mRNA Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of PIK3R1 mRNA]; Rivastigmine inhibits the reaction [Streptozocin results in decreased expression of PIK3R1 mRNA]; Wortmannin inhibits the reaction [Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of PIK3R1 mRNA]] [Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of PIK3R1 protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of PIK3R1 protein] |
CTD |
PMID:32805344 PMID:33484791 |
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NCBI chr13:101,817,269...101,904,725
Ensembl chr13:101,817,071...101,904,725
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G |
Pink1 |
PTEN induced putative kinase 1 |
multiple interactions |
EXP |
[Dietary Fats co-treated with Streptozocin] results in increased expression of PINK1 mRNA |
CTD |
PMID:33812996 |
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NCBI chr 4:138,040,718...138,053,631
Ensembl chr 4:138,040,720...138,053,618
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G |
Pitpnc1 |
phosphatidylinositol transfer protein, cytoplasmic 1 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of PITPNC1 mRNA |
CTD |
PMID:20665664 |
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NCBI chr11:107,098,718...107,361,546
Ensembl chr11:107,098,718...107,361,525
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G |
Pklr |
pyruvate kinase liver and red blood cell |
multiple interactions decreases expression |
ISO EXP |
cinnamaldehyde inhibits the reaction [Streptozocin results in decreased expression of PKLR mRNA]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of PKLR mRNA] [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PKLR protein]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of PKLR protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of PKLR mRNA; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PKLR mRNA] |
CTD |
PMID:20363216 PMID:25446853 PMID:26522834 |
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NCBI chr 3:89,043,429...89,054,122
Ensembl chr 3:89,043,449...89,054,091
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G |
Pkm |
pyruvate kinase, muscle |
affects expression |
EXP |
Streptozocin affects the expression of PKM mRNA |
CTD |
PMID:18583417 |
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NCBI chr 9:59,563,859...59,586,655
Ensembl chr 9:59,563,651...59,586,658
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G |
Pla2g7 |
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of PLA2G7 mRNA |
CTD |
PMID:29127188 |
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NCBI chr17:43,879,009...43,923,093
Ensembl chr17:43,878,989...43,923,092
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G |
Plaat3 |
phospholipase A and acyltransferase 3 |
multiple interactions |
ISO |
[Resveratrol co-treated with Streptozocin] results in increased expression of PLAAT3 mRNA |
CTD |
PMID:25905778 |
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NCBI chr19:7,534,824...7,565,914
Ensembl chr19:7,534,824...7,565,910
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G |
Plau |
plasminogen activator, urokinase |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of PLAU mRNA; Streptozocin results in increased expression of PLAU protein [resveratrol co-treated with Streptozocin] results in increased expression of PLAU mRNA; benazepril inhibits the reaction [Streptozocin results in increased expression of PLAU mRNA] |
CTD |
PMID:15322501 PMID:25905778 |
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NCBI chr14:20,886,730...20,893,456
Ensembl chr14:20,886,728...20,893,453
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G |
Plaur |
plasminogen activator, urokinase receptor |
increases expression multiple interactions |
ISO EXP |
Streptozocin results in increased expression of PLAUR mRNA; Streptozocin results in increased expression of PLAUR protein benazepril inhibits the reaction [Streptozocin results in increased expression of PLAUR mRNA] [Streptozocin co-treated with Dietary Fats] results in increased expression of PLAUR mRNA |
CTD |
PMID:15322501 PMID:29127188 |
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NCBI chr 7:24,161,857...24,175,393
Ensembl chr 7:24,161,909...24,175,393
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G |
Plcb1 |
phospholipase C, beta 1 |
multiple interactions increases expression |
ISO |
acetovanillone inhibits the reaction [Streptozocin results in increased expression of PLCB1 protein]; CAT protein inhibits the reaction [Streptozocin results in increased expression of PLCB1 protein] |
CTD |
PMID:20691780 |
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NCBI chr 2:134,628,084...135,317,178
Ensembl chr 2:134,627,987...135,317,178
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G |
Plcb2 |
phospholipase C, beta 2 |
multiple interactions increases expression |
ISO |
acetovanillone inhibits the reaction [Streptozocin results in increased expression of PLCB2 protein]; CAT protein inhibits the reaction [Streptozocin results in increased expression of PLCB2 protein] |
CTD |
PMID:20691780 |
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NCBI chr 2:118,535,484...118,559,140
Ensembl chr 2:118,537,998...118,558,919
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G |
Plch1 |
phospholipase C, eta 1 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of PLCH1 mRNA |
CTD |
PMID:33484791 |
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NCBI chr 3:63,603,620...63,806,929
Ensembl chr 3:63,603,655...63,806,893
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G |
Plin2 |
perilipin 2 |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in decreased expression of PLIN2 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 4:86,545,147...86,588,518
Ensembl chr 4:86,566,623...86,588,297
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G |
Pln |
phospholamban |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of PLN mRNA; Streptozocin results in decreased expression of PLN protein Triterpenes inhibits the reaction [Streptozocin results in decreased expression of PLN mRNA]; Triterpenes inhibits the reaction [Streptozocin results in decreased expression of PLN protein] |
CTD |
PMID:19000375 |
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NCBI chr10:53,213,782...53,222,095
Ensembl chr10:53,213,763...53,222,083
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G |
Plscr1 |
phospholipid scramblase 1 |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of PLSCR1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 9:92,132,265...92,154,034
Ensembl chr 9:92,131,803...92,154,331
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G |
Pmp22 |
peripheral myelin protein 22 |
multiple interactions decreases expression |
ISO |
Progesterone inhibits the reaction [Streptozocin results in decreased expression of PMP22 mRNA] |
CTD |
PMID:17187935 |
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NCBI chr11:63,019,808...63,050,373
Ensembl chr11:63,019,808...63,050,373
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G |
Pnpla2 |
patatin-like phospholipase domain containing 2 |
multiple interactions |
EXP |
[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of PNPLA2 protein; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of PNPLA2 protein] |
CTD |
PMID:39047806 |
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NCBI chr 7:141,035,101...141,040,656
Ensembl chr 7:141,035,111...141,040,656
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G |
Pnpt1 |
polyribonucleotide nucleotidyltransferase 1 |
affects expression |
EXP |
Streptozocin affects the expression of PNPT1 mRNA |
CTD |
PMID:18583417 |
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NCBI chr11:29,080,236...29,112,010
Ensembl chr11:29,080,744...29,111,828
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G |
Polg |
polymerase (DNA directed), gamma |
affects expression |
EXP |
Streptozocin affects the expression of POLG mRNA |
CTD |
PMID:18583417 |
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NCBI chr 7:79,095,979...79,117,659
Ensembl chr 7:79,095,979...79,116,110
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G |
Polg2 |
polymerase (DNA directed), gamma 2, accessory subunit |
affects expression |
EXP |
Streptozocin affects the expression of POLG2 mRNA |
CTD |
PMID:18583417 |
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NCBI chr11:106,659,030...106,670,363
Ensembl chr11:106,659,079...106,670,363
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G |
Pomc |
pro-opiomelanocortin-alpha |
multiple interactions decreases expression |
ISO |
INS protein inhibits the reaction [Streptozocin results in decreased expression of POMC mRNA] |
CTD |
PMID:20219977 |
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NCBI chr12:4,004,945...4,010,643
Ensembl chr12:4,004,951...4,010,642
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G |
Pon1 |
paraoxonase 1 |
multiple interactions decreases expression decreases activity |
ISO |
[Propolis co-treated with Chlorpyrifos co-treated with Streptozocin] results in decreased expression of PON1 mRNA; [Propolis co-treated with Chlorpyrifos co-treated with Streptozocin] results in decreased expression of PON1 protein; [Propolis co-treated with Streptozocin] results in decreased expression of PON1 protein; [Streptozocin co-treated with Chlorpyrifos] inhibits the reaction [Propolis results in increased expression of PON1 mRNA]; [Streptozocin co-treated with Chlorpyrifos] inhibits the reaction [Propolis results in increased expression of PON1 protein]; [Streptozocin co-treated with Chlorpyrifos] results in decreased expression of PON1 mRNA; [Streptozocin co-treated with Chlorpyrifos] results in decreased expression of PON1 protein; Chlorpyrifos inhibits the reaction [Streptozocin results in decreased expression of PON1 protein]; Chlorpyrifos promotes the reaction [Streptozocin results in decreased expression of PON1 mRNA]; Propolis inhibits the reaction [[Streptozocin co-treated with Chlorpyrifos] results in decreased expression of PON1 mRNA]; Propolis inhibits the reaction [[Streptozocin co-treated with Chlorpyrifos] results in decreased expression of PON1 protein]; Propolis inhibits the reaction [Streptozocin results in decreased expression of PON1 mRNA]; Propolis inhibits the reaction [Streptozocin results in decreased expression of PON1 protein]; Streptozocin inhibits the reaction [Chlorpyrifos results in decreased expression of PON1 protein]; Streptozocin inhibits the reaction [Propolis results in increased expression of PON1 mRNA]; Streptozocin inhibits the reaction [Propolis results in increased expression of PON1 protein]; Streptozocin promotes the reaction [Chlorpyrifos results in decreased expression of PON1 mRNA] Streptozocin results in decreased expression of PON1 mRNA; Streptozocin results in decreased expression of PON1 protein Streptozocin results in decreased activity of PON1 protein |
CTD |
PMID:31400774 PMID:34039237 |
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NCBI chr 6:5,168,101...5,193,824
Ensembl chr 6:5,168,090...5,193,946
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G |
Por |
cytochrome p450 oxidoreductase |
increases expression |
ISO |
Streptozocin results in increased expression of POR mRNA |
CTD |
PMID:25905778 |
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NCBI chr 5:135,698,894...135,764,180
Ensembl chr 5:135,698,887...135,764,180
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G |
Pou1f1 |
POU domain, class 1, transcription factor 1 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of POU1F1 mRNA; Streptozocin results in increased expression of POU1F1 protein INS1 protein inhibits the reaction [Streptozocin results in increased expression of POU1F1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of POU1F1 protein] |
CTD |
PMID:29216956 |
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NCBI chr16:65,317,398...65,331,904
Ensembl chr16:65,317,397...65,331,183
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G |
Pou5f1 |
POU domain, class 5, transcription factor 1 |
multiple interactions |
ISO |
[bisphenol A co-treated with Streptozocin] results in decreased expression of POU5F1 protein |
CTD |
PMID:35187753 |
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NCBI chr17:35,816,929...35,821,674
Ensembl chr17:35,816,915...35,821,669
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G |
Ppara |
peroxisome proliferator activated receptor alpha |
affects response to substance multiple interactions decreases expression increases expression |
EXP ISO |
PPARA protein affects the susceptibility to Streptozocin [Dietary Fats co-treated with Streptozocin] results in decreased expression of PPARA mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of PPARA mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of PPARA protein; [Streptozocin co-treated with Dietary Fats co-treated with Carboxymethylcellulose Sodium] results in decreased expression of PPARA protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARA mRNA; Acrylamide inhibits the reaction [Streptozocin results in increased expression of PPARA mRNA]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PPARA mRNA]; Metformin inhibits the reaction [Streptozocin results in decreased expression of PPARA mRNA]; naringenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Carboxymethylcellulose Sodium] results in decreased expression of PPARA protein]; puerarin inhibits the reaction [Streptozocin results in decreased expression of PPARA mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of PPARA mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of PPARA protein]; TERT protein inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARA mRNA] [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of PPARA mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of PPARA mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of PPARA protein; [Streptozocin co-treated with Cadmium] results in decreased expression of PPARA protein; [Streptozocin co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in increased expression of PPARA protein; Allopurinol inhibits the reaction [Streptozocin results in decreased expression of PPARA mRNA]; Allopurinol inhibits the reaction [Streptozocin results in decreased expression of PPARA protein]; Berberine inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in increased expression of PPARA protein]; Bezafibrate inhibits the reaction [Streptozocin results in decreased expression of PPARA mRNA]; Fenofibrate inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in increased expression of PPARA protein]; idebenone inhibits the reaction [Streptozocin results in increased expression of PPARA protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of PPARA protein]; Plant Extracts inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PPARA mRNA]; Plant Extracts inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PPARA protein]; Quercetin inhibits the reaction [Streptozocin results in decreased expression of PPARA mRNA]; Quercetin inhibits the reaction [Streptozocin results in decreased expression of PPARA protein] Streptozocin results in decreased expression of PPARA mRNA; Streptozocin results in decreased expression of PPARA protein |
CTD |
PMID:12967931 PMID:16306367 PMID:18338635 PMID:23647015 PMID:23927877 PMID:25240712 PMID:25246140 PMID:28648635 PMID:29614383 PMID:29988851 PMID:31063766 PMID:34896238 PMID:35786680 PMID:39047806 PMID:39265716 More...
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NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020
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G |
Ppard |
peroxisome proliferator activator receptor delta |
multiple interactions decreases expression |
ISO EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in increased expression of PPARD protein; Berberine inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in increased expression of PPARD protein]; Fenofibrate inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in increased expression of PPARD protein]; Olive Oil inhibits the reaction [Streptozocin results in decreased expression of PPARD mRNA] [Streptozocin co-treated with Dietary Fats co-treated with Carboxymethylcellulose Sodium] results in decreased expression of PPARB protein; naringenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Carboxymethylcellulose Sodium] results in decreased expression of PPARB protein] |
CTD |
PMID:18338635 PMID:25246140 PMID:31063766 |
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NCBI chr17:28,451,715...28,520,446
Ensembl chr17:28,451,674...28,520,448
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G |
Pparg |
peroxisome proliferator activated receptor gamma |
multiple interactions decreases expression increases expression |
EXP ISO |
[Dietary Fats co-treated with Streptozocin] results in decreased expression of PPARG mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of PPARG mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of PPARG mRNA; [Streptozocin co-treated with Dietary Fats co-treated with Carboxymethylcellulose Sodium] results in decreased expression of PPARG protein; [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of PPARG protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARG mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARG protein; esculetin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of PPARG mRNA]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PPARG mRNA]; MIR29A mRNA inhibits the reaction [Streptozocin results in decreased expression of PPARG mRNA]; MIR29A mRNA inhibits the reaction [Streptozocin results in decreased expression of PPARG protein]; naringenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Carboxymethylcellulose Sodium] results in decreased expression of PPARG protein]; Telmisartan inhibits the reaction [Streptozocin results in decreased expression of PPARG protein]; TERT protein inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARG mRNA] Streptozocin results in decreased expression of PPARG mRNA; Streptozocin results in decreased expression of PPARG protein Streptozocin results in increased expression of PPARG mRNA; Streptozocin results in increased expression of PPARG protein 2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of PPARG protein]; [Streptozocin co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in decreased expression of PPARG protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARG mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARG protein; [Streptozocin co-treated with Isoproterenol] affects the expression of PPARG protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of PPARG protein; allyl isothiocyanate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARG protein]; Berberine inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in decreased expression of PPARG protein]; Bezafibrate inhibits the reaction [Streptozocin results in decreased expression of PPARG mRNA]; bisphenol A diglycidyl ether inhibits the reaction [Calcitriol inhibits the reaction [Streptozocin results in decreased expression of PPARG mRNA]]; bisphenol A diglycidyl ether inhibits the reaction [Calcitriol inhibits the reaction [Streptozocin results in decreased expression of PPARG protein]]; Calcitriol inhibits the reaction [Streptozocin results in decreased expression of PPARG mRNA]; Calcitriol inhibits the reaction [Streptozocin results in decreased expression of PPARG protein]; chebulagic acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARG protein]; esculetin inhibits the reaction [Streptozocin results in decreased expression of PPARG protein]; esculetin inhibits the reaction [Streptozocin results in increased expression of PPARG protein]; eupafolin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of PPARG protein]; Ficusin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARG mRNA]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of PPARG mRNA]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of PPARG protein]; Hesperidin inhibits the reaction [2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of PPARG protein]]; Hesperidin inhibits the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of PPARG protein]; INS protein promotes the reaction [Streptozocin results in increased expression of PPARG mRNA]; mangiferin inhibits the reaction [Streptozocin results in decreased expression of PPARG mRNA]; mangiferin inhibits the reaction [Streptozocin results in decreased expression of PPARG protein]; naringenin inhibits the reaction [Streptozocin results in decreased expression of PPARG mRNA]; naringenin inhibits the reaction [Streptozocin results in decreased expression of PPARG protein]; Olive Oil inhibits the reaction [Streptozocin results in decreased expression of PPARG mRNA]; Pioglitazone inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARG mRNA]; Pioglitazone inhibits the reaction [Streptozocin results in decreased expression of PPARG protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of PPARG protein]; Rosiglitazone inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in decreased expression of PPARG protein]; Rosiglitazone inhibits the reaction [Streptozocin results in decreased expression of PPARG] Streptozocin results in decreased expression of PPARG; Streptozocin results in decreased expression of PPARG mRNA; Streptozocin results in decreased expression of PPARG protein |
CTD |
PMID:12967931 PMID:16980342 PMID:18338635 PMID:20219977 PMID:21381899 PMID:21450970 PMID:23319174 PMID:24136780 PMID:24954035 PMID:25246140 PMID:27350165 PMID:27769711 PMID:29223569 PMID:29953732 PMID:30642005 PMID:30927557 PMID:31063766 PMID:33359794 PMID:33484791 PMID:34175429 PMID:34470562 PMID:37044004 PMID:37566541 PMID:39047806 PMID:39265716 More...
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NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360
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G |
Ppargc1a |
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha |
decreases expression multiple interactions increases expression |
EXP ISO |
Streptozocin results in decreased expression of PPARGC1A protein [Dietary Fats co-treated with Streptozocin] results in decreased expression of PPARGC1A mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARGC1A mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARGC1A protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of PPARGC1A mRNA; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARGC1A protein]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PPARGC1A mRNA]; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of PPARGC1A mRNA]; Telmisartan inhibits the reaction [Streptozocin results in decreased expression of PPARGC1A protein]; TERT protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARGC1A protein]; TERT protein inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARGC1A mRNA]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARGC1A mRNA]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARGC1A protein] Streptozocin results in increased expression of PPARGC1A mRNA Streptozocin results in decreased expression of PPARGC1A mRNA; Streptozocin results in decreased expression of PPARGC1A protein ferulic acid inhibits the reaction [Streptozocin results in decreased expression of PPARGC1A protein]; Olive Oil inhibits the reaction [Streptozocin results in decreased expression of PPARGC1A mRNA]; STUB1 inhibits the reaction [Streptozocin results in decreased expression of PPARGC1A protein] |
CTD |
PMID:21381899 PMID:23319174 PMID:25246140 PMID:26522834 PMID:31029786 PMID:33812996 PMID:35442559 PMID:37337224 PMID:39265716 More...
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NCBI chr 5:51,611,591...52,273,316
Ensembl chr 5:51,611,592...51,725,068
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G |
Ppfia3 |
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of PPFIA3 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of PPFIA3 mRNA] |
CTD |
PMID:33484791 |
|
NCBI chr 7:44,988,550...45,016,443
Ensembl chr 7:44,988,546...45,016,443
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G |
Ppid |
peptidylprolyl isomerase D (cyclophilin D) |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of PPID protein Phosphocreatine inhibits the reaction [Streptozocin results in increased expression of PPID protein] |
CTD |
PMID:34455488 |
|
NCBI chr 3:79,498,644...79,511,117
Ensembl chr 3:79,498,649...79,510,957
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G |
Ppp1r12a |
protein phosphatase 1, regulatory subunit 12A |
multiple interactions increases expression |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of PPP1R12A protein; Angiotensin-Converting Enzyme Inhibitors inhibits the reaction [Streptozocin results in increased expression of PPP1R12A protein modified form]; fasudil inhibits the reaction [Streptozocin results in increased expression of PPP1R12A protein modified form] |
CTD |
PMID:20665664 PMID:22429817 |
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NCBI chr10:107,997,913...108,115,846
Ensembl chr10:107,998,054...108,120,336
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G |
Ppp1r3c |
protein phosphatase 1, regulatory subunit 3C |
decreases expression |
ISO |
Streptozocin results in decreased expression of PPP1R3C mRNA |
CTD |
PMID:25905778 |
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NCBI chr19:36,709,131...36,714,004
Ensembl chr19:36,709,131...36,714,053
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G |
Ppp2ca |
protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform |
multiple interactions decreases methylation decreases expression |
EXP |
5-Methoxypsoralen inhibits the reaction [Streptozocin results in decreased expression of PPP2CA protein modified form]; Folic Acid deficiency promotes the reaction [Streptozocin results in decreased methylation of PPP2CA protein]; Folic Acid inhibits the reaction [Streptozocin results in decreased methylation of PPP2CA protein]; INS1 protein affects the reaction [Streptozocin results in decreased methylation of PPP2CA protein]; Tadalafil inhibits the reaction [Streptozocin results in decreased expression of PPP2CA protein modified form] |
CTD |
PMID:28422052 PMID:34428446 |
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NCBI chr11:51,989,651...52,013,576
Ensembl chr11:51,989,508...52,018,605
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G |
Ppy |
pancreatic polypeptide |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of PPY mRNA |
CTD |
PMID:33484791 |
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NCBI chr11:101,990,757...101,992,145
Ensembl chr11:101,990,756...101,992,145
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G |
Prdx1 |
peroxiredoxin 1 |
multiple interactions decreases expression |
ISO EXP |
PRDX4 protein inhibits the reaction [Streptozocin results in decreased expression of PRDX1 mRNA] |
CTD |
PMID:20446767 |
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NCBI chr 4:116,542,796...116,557,196
Ensembl chr 4:116,542,741...116,558,019
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G |
Prdx2 |
peroxiredoxin 2 |
decreases expression multiple interactions |
EXP ISO |
Streptozocin results in decreased expression of PRDX2 mRNA PRDX4 protein inhibits the reaction [Streptozocin results in decreased expression of PRDX2 mRNA] |
CTD |
PMID:20446767 |
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NCBI chr 8:85,696,251...85,701,440
Ensembl chr 8:85,696,216...85,701,463
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G |
Prdx3 |
peroxiredoxin 3 |
multiple interactions decreases expression |
ISO EXP |
PRDX4 protein inhibits the reaction [Streptozocin results in decreased expression of PRDX3 mRNA] |
CTD |
PMID:20446767 |
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NCBI chr19:60,852,504...60,862,976
Ensembl chr19:60,852,489...60,862,994
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G |
Prdx4 |
peroxiredoxin 4 |
multiple interactions decreases expression |
ISO EXP |
PRDX4 protein inhibits the reaction [Streptozocin results in decreased expression of PRDX1 mRNA]; PRDX4 protein inhibits the reaction [Streptozocin results in decreased expression of PRDX2 mRNA]; PRDX4 protein inhibits the reaction [Streptozocin results in decreased expression of PRDX3 mRNA]; PRDX4 protein inhibits the reaction [Streptozocin results in decreased expression of PRDX4 mRNA]; PRDX4 protein inhibits the reaction [Streptozocin results in decreased expression of PRDX5 mRNA]; PRDX4 protein inhibits the reaction [Streptozocin results in decreased expression of PRDX6 mRNA]; PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of MMP2 mRNA]; PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of MMP3 mRNA]; PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of MMP7 mRNA]; PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of MMP9 mRNA]; PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of TNF mRNA] [Dietary Fats co-treated with Streptozocin] results in decreased expression of PRDX4 mRNA; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PRDX4 mRNA] |
CTD |
PMID:20446767 PMID:33359794 |
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NCBI chr X:154,106,914...154,125,268
Ensembl chr X:154,106,914...154,123,750
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G |
Prdx5 |
peroxiredoxin 5 |
decreases expression multiple interactions |
EXP ISO |
Streptozocin results in decreased expression of PRDX5 mRNA PRDX4 protein inhibits the reaction [Streptozocin results in decreased expression of PRDX5 mRNA] |
CTD |
PMID:20446767 |
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NCBI chr19:6,884,065...6,887,474
Ensembl chr19:6,884,065...6,887,474
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G |
Prdx6 |
peroxiredoxin 6 |
multiple interactions decreases expression |
ISO EXP |
PRDX4 protein inhibits the reaction [Streptozocin results in decreased expression of PRDX6 mRNA] |
CTD |
PMID:20446767 |
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NCBI chr 1:161,067,682...161,078,780
Ensembl chr 1:161,067,682...161,078,789
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G |
Prkaa1 |
protein kinase, AMP-activated, alpha 1 catalytic subunit |
multiple interactions |
ISO EXP |
Streptozocin results in decreased expression of and results in decreased phosphorylation of PRKAA1 protein; STUB1 inhibits the reaction [Streptozocin results in decreased expression of and results in decreased phosphorylation of PRKAA1 protein] [Streptozocin co-treated with Dietary Fats] results in decreased expression of and results in decreased phosphorylation of PRKAA1 protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of PRKAA1 mRNA; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of and results in decreased phosphorylation of PRKAA1 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PRKAA1 mRNA]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of and results in decreased phosphorylation of PRKAA1 protein]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PRKAA1 mRNA] |
CTD |
PMID:35442559 PMID:37337224 |
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NCBI chr15:5,172,641...5,211,380
Ensembl chr15:5,173,343...5,211,380
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G |
Prkaa2 |
protein kinase, AMP-activated, alpha 2 catalytic subunit |
multiple interactions |
ISO EXP |
streptozocin decreases expression and phosphorylation of Prkaa2 protein in liver [Streptozocin co-treated with Dietary Fats] results in decreased expression of PRKAA2 mRNA; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PRKAA2 mRNA]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PRKAA2 mRNA] |
CTD RGD |
PMID:37337224 PMID:32535406 |
RGD:401850547 |
NCBI chr 4:104,886,846...104,967,095
Ensembl chr 4:104,887,071...104,967,087
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G |
Prkaca |
protein kinase, cAMP dependent, catalytic, alpha |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased phosphorylation of PRKACA protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased phosphorylation of PRKACA protein] |
CTD |
PMID:32303808 |
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NCBI chr 8:84,699,607...84,723,073
Ensembl chr 8:84,699,622...84,723,072
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G |
Prkca |
protein kinase C, alpha |
multiple interactions increases expression |
ISO |
Ethanol inhibits the reaction [Streptozocin results in increased expression of PRKCA protein]; procyanidin B2 inhibits the reaction [Streptozocin results in increased expression of PRKCA protein] |
CTD |
PMID:12198386 PMID:25199697 |
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NCBI chr11:107,824,213...108,237,360
Ensembl chr11:107,824,213...108,234,754
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G |
Prkcb |
protein kinase C, beta |
increases phosphorylation multiple interactions |
ISO |
Streptozocin results in increased phosphorylation of PRKCB protein Streptozocin results in increased expression of and results in increased activity of PRKCB protein; tempol inhibits the reaction [Streptozocin results in increased expression of and results in increased activity of PRKCB protein] |
CTD |
PMID:16478977 PMID:16980342 |
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NCBI chr 7:121,888,327...122,233,625
Ensembl chr 7:121,887,974...122,233,625
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G |
Prkcd |
protein kinase C, delta |
multiple interactions increases expression |
ISO |
arjunolic acid inhibits the reaction [Streptozocin results in increased expression of PRKCD protein]; Ethanol inhibits the reaction [Streptozocin results in increased expression of PRKCD protein]; Streptozocin results in increased expression of and results in increased activity of PRKCD protein; tempol inhibits the reaction [Streptozocin results in increased expression of and results in increased activity of PRKCD protein] |
CTD |
PMID:12198386 PMID:16478977 PMID:19682444 |
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NCBI chr14:30,317,310...30,348,637
Ensembl chr14:30,317,311...30,348,167
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G |
Prkce |
protein kinase C, epsilon |
multiple interactions increases expression |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of PRKCE mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of PRKCE protein; arjunolic acid inhibits the reaction [Streptozocin results in increased expression of PRKCE protein]; Ethanol inhibits the reaction [Streptozocin results in increased expression of PRKCE protein] |
CTD |
PMID:12198386 PMID:19682444 PMID:20665664 |
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NCBI chr17:86,472,631...86,965,347
Ensembl chr17:86,475,213...86,965,347
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G |
Prkg1 |
protein kinase, cGMP-dependent, type I |
multiple interactions decreases expression |
EXP |
5-Methoxypsoralen inhibits the reaction [Streptozocin results in decreased expression of PRKG1 protein]; Tadalafil inhibits the reaction [Streptozocin results in decreased expression of PRKG1 protein] |
CTD |
PMID:34428446 |
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NCBI chr19:30,541,887...31,742,675
Ensembl chr19:30,541,889...31,742,433
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G |
Prkg2 |
protein kinase, cGMP-dependent, type II |
multiple interactions |
ISO |
[ALPK1 protein results in increased susceptibility to Streptozocin] which results in decreased expression of PRKG2 mRNA |
CTD |
PMID:27542954 |
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NCBI chr 5:99,077,632...99,185,042
Ensembl chr 5:99,077,632...99,185,210
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G |
Prok1 |
prokineticin 1 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of PROK1 mRNA |
CTD |
PMID:29127188 |
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NCBI chr 3:107,139,232...107,147,023
Ensembl chr 3:107,140,113...107,147,023
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G |
Prok2 |
prokineticin 2 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of PROK2 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of PROK2 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 6:99,687,833...99,703,368
Ensembl chr 6:99,688,260...99,703,353
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G |
Prph |
peripherin |
decreases expression |
ISO |
Streptozocin results in decreased expression of PRPH protein |
CTD |
PMID:30583000 |
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NCBI chr15:98,951,452...98,956,858
Ensembl chr15:98,953,055...98,956,859
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G |
Prtn3 |
proteinase 3 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of PRTN3 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of PRTN3 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr10:79,715,499...79,719,008
Ensembl chr10:79,710,310...79,719,008
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G |
Psd2 |
pleckstrin and Sec7 domain containing 2 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of PSD2 mRNA |
CTD |
PMID:33484791 |
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NCBI chr18:36,075,480...36,147,768
Ensembl chr18:36,097,883...36,147,768
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G |
Psrc1 |
proline/serine-rich coiled-coil 1 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of PSRC1 mRNA |
CTD |
PMID:29127188 |
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NCBI chr 3:108,291,120...108,295,547
Ensembl chr 3:108,291,155...108,295,547
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G |
Pten |
phosphatase and tensin homolog |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of PTEN mRNA; Streptozocin results in increased expression of PTEN protein Phycocyanin inhibits the reaction [Streptozocin results in increased expression of PTEN mRNA]; Rivastigmine inhibits the reaction [Streptozocin results in increased expression of PTEN mRNA]; Wortmannin inhibits the reaction [Phycocyanin inhibits the reaction [Streptozocin results in increased expression of PTEN mRNA]] |
CTD |
PMID:32805344 PMID:38706688 |
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NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560
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G |
Ptgs1 |
prostaglandin-endoperoxide synthase 1 |
multiple interactions increases expression |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of PTGS1 mRNA; acetovanillone inhibits the reaction [Streptozocin results in increased expression of PTGS1 protein] |
CTD |
PMID:12888618 PMID:18414395 PMID:25905778 |
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NCBI chr 2:36,106,758...36,142,287
Ensembl chr 2:36,120,438...36,142,284
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions increases expression increases activity |
ISO EXP |
[1-((4-methylsulfonyl)phenyl)-3-trifluoromethyl-5-(4-fluorophenyl)pyrazole binds to and results in decreased activity of PTGS2 protein] which results in decreased susceptibility to Streptozocin; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of PTGS2 mRNA; [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide binds to and results in decreased activity of PTGS2 protein] which results in decreased susceptibility to Streptozocin; [Telmisartan co-treated with Aspirin] inhibits the reaction [Streptozocin results in increased expression of PTGS2 protein]; acetovanillone inhibits the reaction [Streptozocin results in increased expression of PTGS2 protein]; Aspirin inhibits the reaction [Streptozocin results in increased expression of PTGS2 protein]; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of PTGS2 mRNA]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of PTGS2 mRNA]; Glyburide inhibits the reaction [Streptozocin results in increased expression of PTGS2 mRNA]; IGF2R protein modified form promotes the reaction [Streptozocin results in increased expression of PTGS2 protein]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of PTGS2 mRNA]; Kangen-karyu inhibits the reaction [Streptozocin results in increased expression of PTGS2 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of PTGS2 mRNA]; Rosiglitazone inhibits the reaction [Streptozocin results in increased expression of PTGS2 mRNA]; Rosiglitazone inhibits the reaction [Streptozocin results in increased expression of PTGS2 protein]; Zinc inhibits the reaction [Streptozocin results in increased expression of PTGS2 mRNA] Streptozocin results in increased expression of PTGS2 mRNA; Streptozocin results in increased expression of PTGS2 protein Acrylamide promotes the reaction [Streptozocin results in increased expression of PTGS2 protein]; asiatic acid inhibits the reaction [Streptozocin results in increased activity of PTGS2 protein]; asiatic acid promotes the reaction [Carnosine inhibits the reaction [Streptozocin results in increased activity of PTGS2 protein]]; Carnosine inhibits the reaction [Streptozocin results in increased activity of PTGS2 protein]; Carnosine promotes the reaction [asiatic acid inhibits the reaction [Streptozocin results in increased activity of PTGS2 protein]]; NTN1 protein inhibits the reaction [Streptozocin results in increased expression of PTGS2 protein] |
CTD |
PMID:12888618 PMID:14514642 PMID:17112505 PMID:18414395 PMID:19397970 PMID:20223228 PMID:21791967 PMID:25191525 PMID:29059224 PMID:30802477 PMID:30817903 PMID:31009641 PMID:34896238 PMID:36462176 PMID:36510688 PMID:37081038 More...
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NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
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G |
Ptpn1 |
protein tyrosine phosphatase, non-receptor type 1 |
multiple interactions increases expression |
EXP |
resveratrol inhibits the reaction [Streptozocin results in increased expression of PTPN1 protein] |
CTD |
PMID:25808216 |
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NCBI chr 2:167,772,670...167,821,305
Ensembl chr 2:167,773,977...167,821,305
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G |
Ptprd |
protein tyrosine phosphatase receptor type D |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of PTPRD mRNA |
CTD |
PMID:20665664 |
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NCBI chr 4:75,859,474...78,132,282
Ensembl chr 4:75,859,475...78,130,198
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G |
Ptprm |
protein tyrosine phosphatase receptor type M |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of PTPRM mRNA |
CTD |
PMID:20665664 |
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NCBI chr17:66,973,843...67,661,486
Ensembl chr17:66,973,942...67,661,452
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G |
Ptprt |
protein tyrosine phosphatase receptor type T |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of PTPRT mRNA |
CTD |
PMID:20665664 |
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NCBI chr 2:161,363,908...162,503,106
Ensembl chr 2:161,363,910...162,503,067
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G |
Pycard |
PYD and CARD domain containing |
multiple interactions increases expression |
ISO EXP |
Allopurinol inhibits the reaction [Streptozocin results in increased expression of PYCARD mRNA]; Allopurinol inhibits the reaction [Streptozocin results in increased expression of PYCARD protein]; palbinone inhibits the reaction [Streptozocin results in increased expression of PYCARD protein]; Quercetin inhibits the reaction [Streptozocin results in increased expression of PYCARD mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of PYCARD protein] Streptozocin results in increased expression of PYCARD mRNA; Streptozocin results in increased expression of PYCARD protein [Streptozocin co-treated with Dextran Sulfate] results in increased expression of PYCARD protein |
CTD |
PMID:23647015 PMID:32202043 PMID:34964214 |
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NCBI chr 7:127,590,545...127,593,039
Ensembl chr 7:127,588,880...127,593,039
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G |
Pygl |
liver glycogen phosphorylase |
multiple interactions decreases expression |
ISO |
[Streptozocin co-treated with Niacinamide] affects the activity of PYGL protein; resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] affects the activity of PYGL protein] Streptozocin results in decreased expression of PYGL mRNA |
CTD |
PMID:19059388 PMID:25905778 |
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NCBI chr12:70,237,589...70,274,457
Ensembl chr12:70,237,585...70,278,262
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G |
Pygm |
muscle glycogen phosphorylase |
multiple interactions decreases activity |
ISO |
Plant Extracts inhibits the reaction [Streptozocin results in decreased activity of PYGM protein]; Polysaccharides inhibits the reaction [Streptozocin results in decreased activity of PYGM protein] |
CTD |
PMID:26616445 |
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NCBI chr19:6,434,438...6,448,494
Ensembl chr19:6,434,429...6,448,489
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G |
Pyroxd2 |
pyridine nucleotide-disulphide oxidoreductase domain 2 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of PYROXD2 protein Trientine inhibits the reaction [Streptozocin results in increased expression of PYROXD2 protein] |
CTD |
PMID:19634143 |
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NCBI chr19:42,714,296...42,741,261
Ensembl chr19:42,714,297...42,741,214
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G |
Pyy |
peptide YY |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of PYY mRNA |
CTD |
PMID:33484791 |
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NCBI chr11:101,997,502...101,998,658
Ensembl chr11:101,997,502...101,998,658
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G |
Rac1 |
Rac family small GTPase 1 |
multiple interactions increases activity |
EXP ISO |
Atorvastatin inhibits the reaction [Streptozocin results in increased activity of and results in increased localization of RAC1 protein]; Streptozocin results in increased activity of and results in increased localization of RAC1 protein Atorvastatin inhibits the reaction [Streptozocin results in increased activity of RAC1 protein] |
CTD |
PMID:17279352 PMID:17589825 |
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NCBI chr 5:143,491,236...143,513,786
Ensembl chr 5:143,489,389...143,513,791
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G |
Rac2 |
Rac family small GTPase 2 |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of RAC2 mRNA |
CTD |
PMID:25905778 |
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NCBI chr15:78,443,369...78,456,983
Ensembl chr15:78,443,367...78,456,983
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G |
Raf1 |
v-raf-leukemia viral oncogene 1 |
multiple interactions increases expression decreases expression |
ISO |
manumycin inhibits the reaction [Streptozocin results in increased expression of RAF1 protein]; Simvastatin inhibits the reaction [Streptozocin results in increased expression of RAF1 protein]; xanthoceraside inhibits the reaction [Streptozocin results in decreased expression of RAF1 protein] |
CTD |
PMID:18569938 PMID:23562514 |
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NCBI chr 6:115,595,530...115,653,596
Ensembl chr 6:115,595,028...115,653,596
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G |
Rasgrf1 |
RAS protein-specific guanine nucleotide-releasing factor 1 |
affects localization |
ISO |
Streptozocin affects the localization of RASGRF1 protein |
CTD |
PMID:19002579 |
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NCBI chr 9:89,791,565...89,909,032
Ensembl chr 9:89,791,961...89,909,030
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G |
Rasgrp2 |
RAS, guanyl releasing protein 2 |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of RASGRP2 mRNA |
CTD |
PMID:25905778 |
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NCBI chr19:6,449,038...6,465,243
Ensembl chr19:6,449,370...6,465,246
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G |
Rbm39 |
RNA binding motif protein 39 |
decreases expression |
ISO |
Streptozocin results in decreased expression of RBM39 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 2:155,989,159...156,022,649
Ensembl chr 2:155,989,159...156,022,158
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G |
Rbp4 |
retinol binding protein 4, plasma |
multiple interactions |
ISO |
[Dietary Fats co-treated with Streptozocin] results in increased secretion of RBP4 protein; Berberine inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased secretion of RBP4 protein]; cinnamaldehyde inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased secretion of RBP4 protein]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased secretion of RBP4 protein] |
CTD |
PMID:19080170 |
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NCBI chr19:38,105,068...38,113,769
Ensembl chr19:38,105,077...38,113,729
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G |
Rbpjl |
recombination signal binding protein for immunoglobulin kappa J region-like |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of RBPJL mRNA |
CTD |
PMID:33484791 |
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NCBI chr 2:164,244,996...164,257,368
Ensembl chr 2:164,245,061...164,257,368
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G |
Rdh1 |
retinol dehydrogenase 1 (all trans) |
multiple interactions |
ISO |
[Resveratrol co-treated with Streptozocin] results in decreased expression of RDH2 mRNA |
CTD |
PMID:25905778 |
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NCBI chr10:127,595,595...127,604,168
Ensembl chr10:127,595,590...127,604,166
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G |
Rel |
reticuloendotheliosis oncogene |
multiple interactions |
ISO |
Streptozocin affects the localization of and results in increased activity of REL protein |
CTD |
PMID:19002579 |
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NCBI chr11:23,686,847...23,720,969
Ensembl chr11:23,686,847...23,720,970
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G |
Rela |
v-rel reticuloendotheliosis viral oncogene homolog A (avian) |
multiple interactions increases expression increases phosphorylation affects localization increases activity increases localization |
ISO EXP |
TNF protein inhibits the reaction [Streptozocin results in increased expression of RELA mRNA] Streptozocin results in increased expression of RELA mRNA; Streptozocin results in increased expression of RELA protein; Streptozocin results in increased expression of RELA protein modified form Streptozocin results in increased phosphorylation of RELA protein 2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased phosphorylation of RELA protein]; 5-Methoxypsoralen inhibits the reaction [Streptozocin results in increased expression of RELA protein modified form]; [Streptozocin co-treated with Dextran Sulfate] results in increased phosphorylation of RELA protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of RELA mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of RELA protein; [Streptozocin co-treated with Niacinamide] results in increased phosphorylation of RELA protein; AICA ribonucleotide inhibits the reaction [Streptozocin results in increased phosphorylation of and results in increased activity of RELA protein]; asiatic acid inhibits the reaction [Streptozocin results in increased expression of RELA protein]; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of RELA mRNA]; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of RELA protein]; Carnosine inhibits the reaction [Streptozocin results in increased expression of RELA protein]; Carnosine promotes the reaction [asiatic acid inhibits the reaction [Streptozocin results in increased expression of RELA protein]]; EPHX2 gene mutant form inhibits the reaction [Streptozocin results in increased activity of RELA protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased phosphorylation of RELA protein]; montelukast inhibits the reaction [Streptozocin results in increased expression of and affects the localization of RELA protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Streptozocin promotes the reaction [RELA protein binds to MMP9 promoter]]; NTN1 protein inhibits the reaction [Streptozocin results in increased expression of RELA protein]; Resveratrol inhibits the reaction [Streptozocin results in increased phosphorylation of and results in increased activity of RELA protein]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of RELA protein]; SIRT1 protein inhibits the reaction [Streptozocin promotes the reaction [RELA protein binds to PARP1 protein]]; Streptozocin promotes the reaction [RELA protein binds to MMP9 promoter]; Streptozocin promotes the reaction [RELA protein binds to PARP1 protein]; Streptozocin results in increased expression of and affects the localization of RELA protein; Streptozocin results in increased phosphorylation of and results in increased activity of RELA protein; Tadalafil inhibits the reaction [Streptozocin results in increased expression of RELA protein modified form] 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]; 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of RELA protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of RELA protein; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of RELA protein; [Niacinamide co-treated with Streptozocin] results in increased expression of RELA protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of RELA protein; [Streptozocin co-treated with Niacinamide] results in increased activity of RELA protein; [Streptozocin co-treated with Niacinamide] results in increased expression of RELA protein; [Telmisartan co-treated with Aspirin] inhibits the reaction [Streptozocin results in increased expression of RELA protein]; AC3056 inhibits the reaction [Streptozocin results in increased expression of RELA protein]; Angiotensin Receptor Antagonists inhibits the reaction [Streptozocin results in increased expression of RELA protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased expression of RELA protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased phosphorylation of RELA protein]; Aspirin inhibits the reaction [Streptozocin results in increased expression of RELA protein]; benazepril inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of RELA protein]; bisphenol A diglycidyl ether inhibits the reaction [Calcitriol inhibits the reaction [Streptozocin results in increased expression of and results in decreased phosphorylation of RELA protein]]; Calcitriol inhibits the reaction [Streptozocin results in increased expression of and results in decreased phosphorylation of RELA protein]; chromium mesoporphyrin inhibits the reaction [Hemin inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]]; crocin inhibits the reaction [Streptozocin results in increased expression of RELA protein]; Curcumin inhibits the reaction [Streptozocin affects the localization of RELA protein]; Diosgenin inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]; Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of RELA protein]; fasudil inhibits the reaction [Streptozocin results in increased expression of and affects the localization of RELA protein]; Gallic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of RELA protein]; Gliclazide inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in increased expression of RELA protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of RELA protein]; Gliclazide inhibits the reaction [Streptozocin results in increased expression of RELA protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of RELA protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]; Glyburide inhibits the reaction [Streptozocin results in increased expression of RELA protein]; Hemin inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]; IGF2R protein modified form promotes the reaction [Streptozocin results in increased expression of RELA protein modified form]; mangiferin inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]; nifuroxazide inhibits the reaction [Streptozocin results in increased localization of RELA protein]; Phycocyanin inhibits the reaction [Streptozocin results in increased expression of RELA protein]; pinitol inhibits the reaction [Streptozocin results in increased expression of RELA protein]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]; piperlongumine inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]; Plant Extracts inhibits the reaction [Streptozocin results in increased expression of RELA protein]; Resveratrol inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in increased expression of RELA protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased activity of RELA protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of RELA protein]; Rivastigmine inhibits the reaction [Streptozocin results in increased expression of RELA protein]; Streptozocin affects the localization of and results in decreased activity of RELA protein; Streptozocin promotes the reaction [IGF2R protein modified form results in increased expression of RELA protein modified form]; Streptozocin results in increased expression of and affects the localization of RELA protein; Streptozocin results in increased expression of and results in decreased phosphorylation of RELA protein; Streptozocin results in increased expression of and results in increased phosphorylation of RELA protein; STUB1 inhibits the reaction [Streptozocin results in increased phosphorylation of RELA protein]; Tropisetron inhibits the reaction [Streptozocin results in increased expression of RELA protein]; Wortmannin inhibits the reaction [Phycocyanin inhibits the reaction [Streptozocin results in increased expression of RELA protein]]; Zinc inhibits the reaction [Streptozocin results in increased expression of RELA mRNA] |
CTD |
PMID:17900838 PMID:19002579 PMID:19040617 PMID:19123331 PMID:19133311 PMID:19190261 PMID:19682444 PMID:20053369 PMID:20223228 PMID:20307516 PMID:20424485 PMID:20446767 PMID:20643114 PMID:21439372 PMID:21832210 PMID:22058332 PMID:23376009 PMID:23406761 PMID:23611540 PMID:24740756 PMID:24877639 PMID:25541178 PMID:26341651 PMID:27702591 PMID:28478229 PMID:29059224 PMID:29409856 PMID:29606028 PMID:29953732 PMID:30802477 PMID:31009641 PMID:31323227 PMID:31726037 PMID:32805344 PMID:33724628 PMID:34428446 PMID:34610774 PMID:34964214 PMID:35305976 PMID:35442559 PMID:36462176 PMID:36504472 PMID:36510688 PMID:37044004 PMID:37120126 PMID:37482253 More...
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NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
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G |
Retn |
resistin |
multiple interactions increases expression |
ISO |
resveratrol inhibits the reaction [Streptozocin results in increased expression of RETN protein] |
CTD |
PMID:26071184 |
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NCBI chr 8:3,705,770...3,709,818
Ensembl chr 8:3,705,770...3,710,110
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G |
Rhbdf2 |
rhomboid 5 homolog 2 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of RHBDF2 mRNA; Streptozocin results in increased expression of RHBDF2 protein Diosgenin inhibits the reaction [Streptozocin results in increased expression of RHBDF2 mRNA]; Diosgenin inhibits the reaction [Streptozocin results in increased expression of RHBDF2 protein] |
CTD |
PMID:35305976 |
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NCBI chr11:116,488,991...116,517,786
Ensembl chr11:116,488,991...116,517,845
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G |
Rhoa |
ras homolog family member A |
multiple interactions increases activity increases expression |
ISO |
[Resveratrol co-treated with Ramipril] inhibits the reaction [Streptozocin results in increased expression of RHOA protein]; Atorvastatin inhibits the reaction [Streptozocin results in increased activity of RHOA protein]; Ramipril inhibits the reaction [Streptozocin results in increased expression of RHOA protein] |
CTD |
PMID:17589825 PMID:23376009 PMID:31062909 |
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NCBI chr 9:108,183,359...108,215,142
Ensembl chr 9:108,183,328...108,215,133
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G |
Rnf2 |
ring finger protein 2 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of RNF2 mRNA |
CTD |
PMID:28946194 |
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NCBI chr 1:151,345,159...151,376,562
Ensembl chr 1:151,333,755...151,376,706
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G |
Rock1 |
Rho-associated coiled-coil containing protein kinase 1 |
multiple interactions increases expression increases activity |
ISO |
fasudil inhibits the reaction [Streptozocin results in increased activity of ROCK1 protein]; fasudil inhibits the reaction [Streptozocin results in increased expression of ROCK1 mRNA] Streptozocin results in increased expression of ROCK1 mRNA; Streptozocin results in increased expression of ROCK1 protein |
CTD |
PMID:22429817 PMID:23376009 PMID:31062909 |
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NCBI chr18:10,064,401...10,182,225
Ensembl chr18:10,064,401...10,182,045
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G |
Rock2 |
Rho-associated coiled-coil containing protein kinase 2 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of ROCK2 protein [Resveratrol co-treated with Ramipril] inhibits the reaction [Streptozocin results in increased expression of ROCK2 protein]; Ramipril inhibits the reaction [Streptozocin results in increased expression of ROCK2 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of ROCK2 protein] |
CTD |
PMID:31062909 |
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NCBI chr12:16,944,808...17,038,275
Ensembl chr12:16,944,896...17,037,824
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G |
Rpl18a |
ribosomal protein L18A |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of RPL18A mRNA vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of RPL18A mRNA] |
CTD |
PMID:16684804 |
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NCBI chr 8:71,347,366...71,350,087
Ensembl chr 8:71,347,366...71,350,056
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G |
Rprm |
reprimo, TP53 dependent G2 arrest mediator candidate |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of RPRM mRNA |
CTD |
PMID:25905778 |
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NCBI chr 2:53,974,105...53,975,564
Ensembl chr 2:53,974,105...53,975,564
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G |
Rps3 |
ribosomal protein S3 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of RPS3 mRNA vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of RPS3 mRNA] |
CTD |
PMID:16684804 |
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NCBI chr 7:99,127,103...99,132,916
Ensembl chr 7:99,127,103...99,132,945
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G |
Rrad |
Ras-related associated with diabetes |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of RRAD mRNA vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of RRAD mRNA] |
CTD |
PMID:16684804 |
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NCBI chr 8:105,354,702...105,357,921
Ensembl chr 8:105,354,702...105,357,959
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G |
Runx2 |
runt related transcription factor 2 |
decreases expression |
ISO |
Streptozocin results in decreased expression of RUNX2 mRNA |
CTD |
PMID:25617479 |
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NCBI chr17:44,806,873...45,125,518
Ensembl chr17:44,806,874...45,125,684
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G |
Rwdd2a |
RWD domain containing 2A |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of RWDD2A mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of RWDD2A mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 9:86,454,041...86,456,952
Ensembl chr 9:86,454,044...86,456,952
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G |
Ryr2 |
ryanodine receptor 2, cardiac |
decreases activity multiple interactions decreases expression |
ISO EXP |
Streptozocin results in decreased activity of RYR2 protein [octylphenol co-treated with Streptozocin] results in increased expression of RYR2 mRNA Triterpenes inhibits the reaction [Streptozocin results in decreased expression of RYR2 mRNA] |
CTD |
PMID:16685413 PMID:19000375 PMID:29935216 |
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NCBI chr13:11,567,985...12,121,831
Ensembl chr13:11,567,988...12,121,831
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G |
S100a6 |
S100 calcium binding protein A6 (calcyclin) |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of S100A6 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 3:90,520,491...90,531,797
Ensembl chr 3:90,520,189...90,531,488
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G |
S100a8 |
S100 calcium binding protein A8 (calgranulin A) |
multiple interactions increases expression |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of S100A8 mRNA; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Streptozocin results in increased expression of S100A8 mRNA] |
CTD |
PMID:19833897 PMID:29127188 |
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NCBI chr 3:90,576,378...90,577,341
Ensembl chr 3:90,576,285...90,577,342
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G |
S100a9 |
S100 calcium binding protein A9 (calgranulin B) |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of S100A9 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 3:90,599,937...90,603,028
Ensembl chr 3:90,599,939...90,603,028
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G |
S100b |
S100 protein, beta polypeptide, neural |
multiple interactions increases expression decreases expression |
ISO |
pimagedine inhibits the reaction [Streptozocin results in decreased expression of S100B protein]; pimagedine inhibits the reaction [Streptozocin results in increased expression of S100B protein] |
CTD |
PMID:19494442 PMID:20953641 |
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NCBI chr10:76,089,670...76,097,153
Ensembl chr10:76,089,687...76,096,993
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G |
S1pr2 |
sphingosine-1-phosphate receptor 2 |
increases expression |
ISO |
Streptozocin results in increased expression of S1PR2 mRNA |
CTD |
PMID:22406263 |
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NCBI chr 9:20,877,248...20,888,089
Ensembl chr 9:20,873,657...20,888,077
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G |
S1pr4 |
sphingosine-1-phosphate receptor 4 |
increases expression |
ISO |
Streptozocin results in increased expression of S1PR4 mRNA |
CTD |
PMID:22406263 |
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NCBI chr10:81,333,579...81,335,971
Ensembl chr10:81,333,581...81,335,966
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G |
S1pr5 |
sphingosine-1-phosphate receptor 5 |
increases expression |
ISO |
Streptozocin results in increased expression of S1PR5 mRNA |
CTD |
PMID:22406263 |
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NCBI chr 9:21,154,213...21,159,739
Ensembl chr 9:21,154,208...21,159,739
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G |
Saa1 |
serum amyloid A 1 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of SAA1 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of SAA1 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 7:46,389,921...46,392,404
Ensembl chr 7:46,389,921...46,392,404
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G |
Saa2 |
serum amyloid A 2 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of SAA2 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of SAA2 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 7:46,401,257...46,403,737
Ensembl chr 7:46,401,214...46,403,737
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G |
Saa3 |
serum amyloid A 3 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of SAA3 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of SAA3 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 7:46,361,422...46,365,100
Ensembl chr 7:46,361,422...46,365,124
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G |
Scara5 |
scavenger receptor class A, member 5 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of SCARA5 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of SCARA5 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr14:65,903,852...66,002,275
Ensembl chr14:65,903,852...66,002,275
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G |
Scd1 |
stearoyl-Coenzyme A desaturase 1 |
multiple interactions increases expression increases expression |
EXP ISO |
[Dietary Fats co-treated with Streptozocin] results in increased expression of SCD1 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of SCD1 mRNA; Acrylamide inhibits the reaction [Streptozocin results in increased expression of SCD1 mRNA]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SCD1 mRNA] [[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in decreased expression of SCD1 mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of SCD1 mRNA; [Dietary Fats affects the susceptibility to Streptozocin] which results in decreased expression of SCD1 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of SCD1 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of SCD1 mRNA streptozocin increases expression of Scd protein in liver |
CTD RGD |
PMID:29127188 PMID:29988851 PMID:34896238 PMID:35786680 PMID:32535406 |
RGD:401850547 |
NCBI chr19:44,382,889...44,396,148
Ensembl chr19:44,382,894...44,396,318
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G |
Sdha |
succinate dehydrogenase complex, subunit A, flavoprotein (Fp) |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of SDHA protein Trientine inhibits the reaction [Streptozocin results in increased expression of SDHA protein] |
CTD |
PMID:19634143 PMID:21136691 |
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NCBI chr13:74,470,374...74,498,359
Ensembl chr13:74,470,373...74,498,399
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G |
Sdhb |
succinate dehydrogenase complex, subunit B, iron sulfur (Ip) |
multiple interactions increases expression |
ISO EXP |
Trientine inhibits the reaction [Streptozocin results in increased expression of SDHB protein] [Streptozocin co-treated with Dietary Fats] results in decreased expression of SDHB mRNA; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SDHB mRNA]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SDHB mRNA] |
CTD |
PMID:19634143 PMID:37337224 |
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NCBI chr 4:140,688,582...140,706,509
Ensembl chr 4:140,688,514...140,706,504
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G |
Sds |
serine dehydratase |
multiple interactions |
ISO |
[Resveratrol co-treated with Streptozocin] results in decreased expression of SDS mRNA |
CTD |
PMID:25905778 |
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NCBI chr 5:120,614,612...120,621,997
Ensembl chr 5:120,614,591...120,621,997
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G |
Selenop |
selenoprotein P |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of SELENOP mRNA; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of SELENOP mRNA] |
CTD |
PMID:26522834 |
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NCBI chr15:3,300,249...3,309,992
Ensembl chr15:3,298,029...3,309,990
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G |
Selp |
selectin, platelet |
multiple interactions |
ISO |
[Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in increased expression of SELP protein]; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in increased expression of SELP protein]] |
CTD |
PMID:36547818 |
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NCBI chr 1:163,942,833...163,977,595
Ensembl chr 1:163,942,833...163,977,595
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G |
Serpina4-ps1 |
serine (or cysteine) peptidase inhibitor, clade A, member 4, pseudogene 1 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of SERPINA4-PS1 mRNA |
CTD |
PMID:33484791 |
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NCBI chr12:104,044,218...104,053,179
Ensembl chr12:104,046,908...104,052,983
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G |
Serpina6 |
serine (or cysteine) peptidase inhibitor, clade A, member 6 |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in decreased expression of SERPINA6 mRNA |
CTD |
PMID:25905778 |
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NCBI chr12:103,612,889...103,623,477
Ensembl chr12:103,612,889...103,623,471
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G |
Serpina7 |
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of SERPINA7 mRNA |
CTD |
PMID:25905778 |
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NCBI chr X:137,979,998...137,985,985
Ensembl chr X:137,980,006...137,985,985
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G |
Serpine1 |
serine (or cysteine) peptidase inhibitor, clade E, member 1 |
multiple interactions increases expression |
EXP ISO |
SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of SERPINE1 mRNA]; SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of SERPINE1]; Streptozocin promotes the reaction [MAP3K5 protein results in increased expression of SERPINE1 protein]; sulforaphane inhibits the reaction [Streptozocin results in increased expression of SERPINE1 protein] benazepril inhibits the reaction [Streptozocin results in increased expression of SERPINE1 mRNA]; Trientine inhibits the reaction [Streptozocin results in increased expression of SERPINE1 mRNA]; Zinc inhibits the reaction [Streptozocin results in increased expression of SERPINE1 protein] Streptozocin results in increased expression of SERPINE1 mRNA; Streptozocin results in increased expression of SERPINE1 protein Streptozocin results in increased expression of SERPINE1; Streptozocin results in increased expression of SERPINE1 mRNA; Streptozocin results in increased expression of SERPINE1 protein |
CTD |
PMID:15322501 PMID:16731828 PMID:16973718 PMID:19369054 PMID:21778425 PMID:22744176 PMID:24967692 More...
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NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122
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G |
Serpine2 |
serine (or cysteine) peptidase inhibitor, clade E, member 2 |
multiple interactions |
EXP |
[Dietary Fats co-treated with Streptozocin] results in increased expression of SERPINE2 protein; Rosuvastatin Calcium inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SERPINE2 protein]; sarpogrelate inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SERPINE2 protein] |
CTD |
PMID:27097221 |
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NCBI chr 1:79,772,038...79,836,382
Ensembl chr 1:79,771,914...79,838,897
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G |
Serpinh1 |
serine (or cysteine) peptidase inhibitor, clade H, member 1 |
increases expression |
ISO |
Streptozocin results in increased expression of SERPINH1 protein |
CTD |
PMID:12197670 |
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NCBI chr 7:98,994,583...99,002,321
Ensembl chr 7:98,994,583...99,002,446
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G |
Setd7 |
SET domain containing (lysine methyltransferase) 7 |
multiple interactions |
ISO |
Streptozocin promotes the reaction [SETD7 protein binds to CDKN1A promoter] |
CTD |
PMID:27652271 |
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NCBI chr 3:51,422,740...51,468,519
Ensembl chr 3:51,422,740...51,468,300
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Sfxn1 |
sideroflexin 1 |
multiple interactions increases expression |
ISO |
Trientine inhibits the reaction [Streptozocin results in increased expression of SFXN1 protein] |
CTD |
PMID:19634143 |
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NCBI chr13:54,225,675...54,262,365
Ensembl chr13:54,225,888...54,262,361
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G |
Sgk1 |
serum/glucocorticoid regulated kinase 1 |
increases expression |
EXP |
Streptozocin results in increased expression of SGK1 mRNA; Streptozocin results in increased expression of SGK1 protein |
CTD |
PMID:16116964 |
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NCBI chr10:21,758,083...21,875,802
Ensembl chr10:21,758,083...21,875,802
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Sgk2 |
serum/glucocorticoid regulated kinase 2 |
increases expression |
EXP |
Streptozocin results in increased expression of SGK2 mRNA |
CTD |
PMID:16116964 |
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NCBI chr 2:162,829,249...162,856,059
Ensembl chr 2:162,829,250...162,856,047
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Sgk3 |
serum/glucocorticoid regulated kinase 3 |
increases expression |
EXP |
Streptozocin results in increased expression of SGK3 mRNA |
CTD |
PMID:16116964 |
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NCBI chr 1:9,868,355...9,972,795
Ensembl chr 1:9,868,332...9,971,070
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Sh3glb1 |
SH3-domain GRB2-like B1 (endophilin) |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of SH3GLB1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 3:144,389,426...144,426,186
Ensembl chr 3:144,389,439...144,426,096
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G |
Shc1 |
src homology 2 domain-containing transforming protein C1 |
multiple interactions increases expression |
EXP |
SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of SHC1 mRNA]; SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of SHC1 protein] Streptozocin results in increased expression of SHC1 mRNA; Streptozocin results in increased expression of SHC1 protein |
CTD |
PMID:21778425 |
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NCBI chr 3:89,325,858...89,337,336
Ensembl chr 3:89,325,750...89,337,334
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Sim2 |
single-minded family bHLH transcription factor 2 |
increases expression |
ISO |
Streptozocin results in increased expression of SIM2 protein |
CTD |
PMID:23333261 |
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NCBI chr16:93,885,963...93,927,891
Ensembl chr16:93,885,790...93,927,891
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Sirt1 |
sirtuin 1 |
decreases activity multiple interactions decreases expression |
EXP ISO |
Streptozocin results in decreased activity of SIRT1 protein [Dietary Fats co-treated with Streptozocin] results in decreased expression of SIRT1 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of SIRT1 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of SIRT1 protein; AICA ribonucleotide inhibits the reaction [Streptozocin results in decreased activity of SIRT1 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SIRT1 protein]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SIRT1 mRNA]; Plant Extracts inhibits the reaction [Streptozocin results in decreased expression of SIRT1 protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased activity of SIRT1 protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of SIRT1 protein]; SIRT1 protein inhibits the reaction [Streptozocin promotes the reaction [JUN protein binds to PARP1 protein]]; SIRT1 protein inhibits the reaction [Streptozocin promotes the reaction [PARP1 protein binds to MMP9 promoter]]; SIRT1 protein inhibits the reaction [Streptozocin promotes the reaction [RELA protein binds to PARP1 protein]]; SIRT1 protein inhibits the reaction [Streptozocin results in decreased expression of SOD2 protein]; SIRT1 protein inhibits the reaction [Streptozocin results in decreased expression of SOD2]; SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of CDKN1A]; SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of SERPINE1 mRNA]; SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of SERPINE1]; SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of SHC1 mRNA]; SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of SHC1 protein]; SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of TRP53]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SIRT1 mRNA]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SIRT1 protein] [Streptozocin co-treated with bisphenol A] results in decreased expression of SIRT1 protein; [Streptozocin co-treated with Resveratrol co-treated with Ramipril] results in increased expression of SIRT1 protein; [Streptozocin co-treated with Resveratrol] results in increased expression of SIRT1 protein; Organoselenium Compounds inhibits the reaction [Streptozocin results in decreased expression of SIRT1 protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of SIRT1 mRNA]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of SIRT1 protein]; STUB1 inhibits the reaction [Streptozocin results in decreased expression of SIRT1 protein] Streptozocin results in decreased expression of SIRT1 mRNA; Streptozocin results in decreased expression of SIRT1 protein |
CTD |
PMID:21778425 PMID:22058332 PMID:22733486 PMID:22744176 PMID:23792339 PMID:23859249 PMID:24740756 PMID:24889822 PMID:25301743 PMID:28478229 PMID:31062909 PMID:33812996 PMID:35187753 PMID:35442559 PMID:37337224 More...
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NCBI chr10:63,154,784...63,174,814
Ensembl chr10:63,154,784...63,217,483
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G |
Slc10a2 |
solute carrier family 10, member 2 |
multiple interactions |
EXP |
[Dietary Fats co-treated with Streptozocin] results in increased expression of SLC10A2 mRNA |
CTD |
PMID:29382564 |
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NCBI chr 8:5,133,219...5,155,287
Ensembl chr 8:5,133,219...5,155,351
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G |
Slc13a5 |
solute carrier family 13 (sodium-dependent citrate transporter), member 5 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of SLC13A5 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of SLC13A5 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr11:72,132,816...72,158,092
Ensembl chr11:72,132,815...72,158,048
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Slc15a3 |
solute carrier family 15, member 3 |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of SLC15A3 mRNA |
CTD |
PMID:25905778 |
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NCBI chr19:10,819,908...10,835,279
Ensembl chr19:10,817,091...10,836,726
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G |
Slc1a3 |
solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
multiple interactions decreases expression |
ISO |
Curcumin inhibits the reaction [Streptozocin results in decreased expression of SLC1A3 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in decreased expression of SLC1A3 mRNA]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of SLC1A3 mRNA]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of SLC1A3 protein] Streptozocin results in decreased expression of SLC1A3 mRNA; Streptozocin results in decreased expression of SLC1A3 protein |
CTD |
PMID:23267840 PMID:26677078 |
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NCBI chr15:8,663,608...8,742,648
Ensembl chr15:8,663,608...8,740,248
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Slc20a2 |
solute carrier family 20, member 2 |
multiple interactions increases expression |
EXP |
INS1 protein inhibits the reaction [Streptozocin results in increased expression of SLC20A2 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of SLC20A2 protein] Streptozocin results in increased expression of SLC20A2 mRNA; Streptozocin results in increased expression of SLC20A2 protein |
CTD |
PMID:29216956 |
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NCBI chr 8:22,966,771...23,059,632
Ensembl chr 8:22,966,804...23,059,628
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G |
Slc22a1 |
solute carrier family 22 (organic cation transporter), member 1 |
decreases expression |
ISO |
Streptozocin results in decreased expression of SLC22A1 protein |
CTD |
PMID:19605544 |
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NCBI chr17:12,867,761...12,894,725
Ensembl chr17:12,867,756...12,894,716
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G |
Slc22a2 |
solute carrier family 22 (organic cation transporter), member 2 |
decreases expression |
ISO |
Streptozocin results in decreased expression of SLC22A2 protein |
CTD |
PMID:19605544 |
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NCBI chr17:12,803,076...12,847,376
Ensembl chr17:12,803,019...12,847,375
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G |
Slc22a29 |
solute carrier family 22. member 29 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of SLC22A29 mRNA |
CTD |
PMID:33484791 |
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NCBI chr19:8,137,532...8,230,739
Ensembl chr19:8,137,529...8,196,264
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G |
Slc22a6 |
solute carrier family 22 (organic anion transporter), member 6 |
multiple interactions decreases expression |
ISO |
Trientine inhibits the reaction [Streptozocin results in decreased expression of SLC22A6 protein] |
CTD |
PMID:19634143 |
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NCBI chr19:8,595,360...8,605,663
Ensembl chr19:8,595,403...8,605,663
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G |
Slc25a1 |
solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1 |
multiple interactions decreases expression |
ISO |
cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SLC25A1 protein]; tin mesoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SLC25A1 protein]] |
CTD |
PMID:16595661 |
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NCBI chr16:17,743,075...17,746,083
Ensembl chr16:17,743,087...17,746,083
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G |
Slc25a10 |
solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10 |
increases expression multiple interactions decreases expression |
ISO |
Streptozocin results in increased expression of SLC25A10 protein cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SLC25A10 protein]; tin mesoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SLC25A10 protein]]; Trientine inhibits the reaction [Streptozocin results in increased expression of SLC25A10 protein] |
CTD |
PMID:16595661 PMID:19634143 |
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NCBI chr11:120,382,663...120,391,987
Ensembl chr11:120,382,666...120,390,013
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Slc25a19 |
solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19 |
multiple interactions decreases expression |
ISO |
HMOX1 protein inhibits the reaction [Streptozocin results in decreased expression of SLC25A19 protein] cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SLC25A19 protein]; tin mesoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SLC25A19 protein]] |
CTD |
PMID:16595661 |
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NCBI chr11:115,504,991...115,519,122
Ensembl chr11:115,505,004...115,519,121
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G |
Slc25a20 |
solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20 |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of SLC25A20 protein cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SLC25A20 protein]; tin mesoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SLC25A20 protein]] |
CTD |
PMID:16595661 |
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NCBI chr 9:108,539,335...108,561,841
Ensembl chr 9:108,539,287...108,561,840
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G |
Slc25a26 |
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 26 |
affects expression |
EXP |
Streptozocin affects the expression of SLC25A26 mRNA |
CTD |
PMID:18583417 |
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NCBI chr 6:94,477,272...94,581,636
Ensembl chr 6:94,477,312...94,581,653
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G |
Slc25a3 |
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of SLC25A3 protein Trientine inhibits the reaction [Streptozocin results in increased expression of SLC25A3 protein] |
CTD |
PMID:19634143 |
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NCBI chr10:90,952,436...90,959,902
Ensembl chr10:90,952,436...90,959,921
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G |
Slc25a4 |
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4 |
multiple interactions |
EXP |
SLC25A4 protein inhibits the reaction [Streptozocin results in increased expression of NPPA mRNA] |
CTD |
PMID:18945756 |
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NCBI chr 8:46,660,205...46,664,099
Ensembl chr 8:46,659,834...46,664,321
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G |
Slc25a47 |
solute carrier family 25, member 47 |
affects expression |
EXP |
Streptozocin affects the expression of SLC25A47 mRNA |
CTD |
PMID:18583417 |
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NCBI chr12:108,815,740...108,822,741
Ensembl chr12:108,801,972...108,822,741
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G |
Slc25a5 |
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of SLC25A5 protein Trientine inhibits the reaction [Streptozocin results in increased expression of SLC25A5 protein] |
CTD |
PMID:19634143 |
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NCBI chr X:36,059,250...36,062,461
Ensembl chr X:36,059,304...36,062,460
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G |
Slc27a1 |
solute carrier family 27 (fatty acid transporter), member 1 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of SLC27A1 mRNA vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of SLC27A1 mRNA] |
CTD |
PMID:16684804 |
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NCBI chr 8:72,021,372...72,039,951
Ensembl chr 8:72,021,526...72,039,946
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G |
Slc27a5 |
solute carrier family 27 (fatty acid transporter), member 5 |
multiple interactions |
EXP |
[Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC27A5 mRNA |
CTD |
PMID:29382564 |
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NCBI chr 7:12,722,273...12,732,119
Ensembl chr 7:12,722,273...12,732,119
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G |
Slc2a1 |
solute carrier family 2 (facilitated glucose transporter), member 1 |
multiple interactions increases expression |
ISO |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A1 protein; bicalutamide promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A1 protein]; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in increased expression of SLC2A1 mRNA] |
CTD |
PMID:16409969 PMID:35151640 |
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NCBI chr 4:118,966,001...118,994,527
Ensembl chr 4:118,965,908...118,995,180
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G |
Slc2a2 |
solute carrier family 2 (facilitated glucose transporter), member 2 |
increases response to substance decreases expression multiple interactions increases expression |
ISO EXP |
SLC2A2 protein results in increased susceptibility to Streptozocin Streptozocin results in decreased expression of SLC2A2 mRNA 5-thio-D-glucose inhibits the reaction [Streptozocin results in decreased expression of SLC2A2 mRNA]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A2 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A2 protein; Dibutyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A2 protein]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A2 mRNA]; L 783281 inhibits the reaction [Dibutyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A2 protein]] [Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A2 mRNA; [Streptozocin co-treated with Cadmium] results in decreased expression of SLC2A2 protein; allyl isothiocyanate inhibits the reaction [Streptozocin promotes the reaction [Dietary Fats results in decreased expression of SLC2A2 protein]]; allyl methyl sulfide inhibits the reaction [Streptozocin results in decreased expression of SLC2A2 protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of SLC2A2 protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of SLC2A2 protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased expression of SLC2A2 protein]; myrtenal inhibits the reaction [Streptozocin results in decreased expression of SLC2A2 protein]; piperlongumine inhibits the reaction [Streptozocin results in decreased expression of SLC2A2 protein]; repaglinide analog affects the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A2 mRNA]; repaglinide inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A2 mRNA]; Streptozocin promotes the reaction [Dietary Fats results in decreased expression of SLC2A2 protein]; Zinc inhibits the reaction [Streptozocin results in increased expression of SLC2A2 protein] |
CTD |
PMID:11151762 PMID:12137914 PMID:24923654 PMID:25541178 PMID:27417257 PMID:29526571 PMID:30318971 PMID:30927557 PMID:31009641 PMID:33359794 PMID:33724628 PMID:35702883 More...
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NCBI chr 3:28,752,052...28,782,510
Ensembl chr 3:28,752,052...28,785,508
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G |
Slc2a4 |
solute carrier family 2 (facilitated glucose transporter), member 4 |
affects expression affects localization decreases expression multiple interactions |
ISO EXP |
Streptozocin affects the expression of SLC2A4 protein Streptozocin affects the localization of SLC2A4 protein Streptozocin results in decreased expression of SLC2A4 mRNA; Streptozocin results in decreased expression of SLC2A4 protein [Dietary Fats co-treated with Streptozocin co-treated with Quercetin] affects the expression of SLC2A4 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A4 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A4 protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A4 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A4 protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of SLC2A4 protein; asiatic acid inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]; Berberine inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A4 protein]; bis(maltolato)oxovanadium(IV) inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]; chebulagic acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A4 protein]; chromium mesoporphyrin inhibits the reaction [Hemin inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]]; cinnamaldehyde inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A4 protein]; cinnamaldehyde inhibits the reaction [Streptozocin affects the localization of SLC2A4 protein]; eupafolin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of SLC2A4 protein]; Ficusin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A4 mRNA]; GHRL protein promotes the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]; Hemin inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]; INS protein inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]; mangiferin inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]; mangiferin inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A4 protein]; myrtenal inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]; naloxonazine inhibits the reaction [Valsartan inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]]; naloxonazine inhibits the reaction [Valsartan inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]]; Naloxone inhibits the reaction [Tramadol inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]]; naringenin inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]; naringenin inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]; nerolidol inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A4 protein]; Pioglitazone inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A4 mRNA]; piperlongumine inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]; Plant Extracts inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A4 mRNA]; Plant Extracts inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A4 protein]; Plant Extracts inhibits the reaction [Streptozocin affects the localization of SLC2A4 protein]; plumbagin inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]; plumbagin inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]; Polysaccharides inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]; Polysaccharides inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of SLC2A4 protein]; Resveratrol inhibits the reaction [Streptozocin inhibits the reaction [CAV3 protein binds to SLC2A4 protein]]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]; Streptozocin inhibits the reaction [CAV3 protein binds to SLC2A4 protein]; Tramadol inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]; Tramadol inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]; Valsartan inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]; Valsartan inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein] [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A4 protein; [Streptozocin co-treated with bisphenol A] results in decreased expression of SLC2A4 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A4 protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A4 protein]; Metformin inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A4 protein]; Streptozocin inhibits the reaction [Ethinyl Estradiol results in increased expression of SLC2A4 mRNA]; Streptozocin inhibits the reaction [octylphenol results in increased expression of SLC2A4 mRNA] |
CTD |
PMID:11723065 PMID:12083368 PMID:12658023 PMID:17068109 PMID:17199717 PMID:18266981 PMID:19080170 PMID:19190261 PMID:20219977 PMID:20363216 PMID:21439094 PMID:22960630 PMID:24140466 PMID:26286522 PMID:26616445 PMID:27350165 PMID:27417257 PMID:29223569 PMID:29614383 PMID:29935216 PMID:31743741 PMID:33484791 PMID:33724628 PMID:34470562 PMID:36169646 PMID:37566541 More...
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NCBI chr11:69,833,112...69,839,040
Ensembl chr11:69,833,365...69,839,014
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G |
Slc31a1 |
solute carrier family 31, member 1 |
decreases expression |
ISO |
Streptozocin results in decreased expression of SLC31A1 mRNA; Streptozocin results in decreased expression of SLC31A1 protein |
CTD |
PMID:24927960 |
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NCBI chr 4:62,278,821...62,310,006
Ensembl chr 4:62,278,964...62,310,006
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G |
Slc31a2 |
solute carrier family 31, member 2 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of SLC31A2 mRNA; Streptozocin results in increased expression of SLC31A2 protein Trientine promotes the reaction [Streptozocin results in increased expression of SLC31A2 mRNA]; Trientine promotes the reaction [Streptozocin results in increased expression of SLC31A2 protein] |
CTD |
PMID:24927960 |
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NCBI chr 4:62,198,630...62,216,649
Ensembl chr 4:62,180,799...62,216,648
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G |
Slc35b2 |
solute carrier family 35, member B2 |
multiple interactions decreases expression |
ISO |
cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SLC35B2 protein]; tin mesoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SLC35B2 protein]] |
CTD |
PMID:16595661 |
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NCBI chr17:45,874,844...45,878,597
Ensembl chr17:45,874,800...45,878,597
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G |
Slc3a1 |
solute carrier family 3, member 1 |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of SLC3A1 protein Trientine inhibits the reaction [Streptozocin results in decreased expression of SLC3A1 protein] |
CTD |
PMID:19634143 |
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NCBI chr17:85,335,775...85,371,669
Ensembl chr17:85,335,804...85,371,664
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G |
Slc51a |
solute carrier family 51, alpha subunit |
multiple interactions |
EXP |
[Dietary Fats co-treated with Streptozocin] results in increased expression of SLC51A mRNA |
CTD |
PMID:29382564 |
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NCBI chr16:32,294,396...32,306,697
Ensembl chr16:32,293,322...32,306,697
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G |
Slc51b |
solute carrier family 51, beta subunit |
multiple interactions |
EXP |
[Dietary Fats co-treated with Streptozocin] results in increased expression of SLC51B mRNA |
CTD |
PMID:29382564 |
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NCBI chr 9:65,320,035...65,330,055
Ensembl chr 9:65,319,996...65,330,237
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G |
Slc6a20a |
solute carrier family 6 (neurotransmitter transporter), member 20A |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of SLC6A20A mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of SLC6A20A mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 9:123,465,972...123,507,897
Ensembl chr 9:123,463,835...123,507,950
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G |
Slc6a4 |
solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased activity of SLC6A4 protein; [Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of SLC6A4 mRNA; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased activity of SLC6A4 protein]; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of SLC6A4 mRNA] |
CTD |
PMID:32303808 |
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NCBI chr11:76,889,423...76,923,169
Ensembl chr11:76,889,429...76,923,166
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G |
Slc6a6 |
solute carrier family 6 (neurotransmitter transporter, taurine), member 6 |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of SLC6A6 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 6:91,661,031...91,736,044
Ensembl chr 6:91,661,034...91,736,047
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G |
Slc7a7 |
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7 |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of SLC7A7 mRNA |
CTD |
PMID:25905778 |
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NCBI chr14:54,606,899...54,657,525
Ensembl chr14:54,606,899...54,655,237
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G |
Slco1a1 |
solute carrier organic anion transporter family, member 1a1 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of SLCO1A1 mRNA |
CTD |
PMID:29127188 |
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NCBI chr 6:141,853,007...141,892,688
Ensembl chr 6:141,853,008...141,892,688
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G |
Smad1 |
SMAD family member 1 |
increases expression |
ISO |
Streptozocin results in increased expression of SMAD1 |
CTD |
PMID:25617480 |
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NCBI chr 8:80,065,024...80,126,057
Ensembl chr 8:80,065,024...80,126,147
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G |
Smad2 |
SMAD family member 2 |
increases phosphorylation multiple interactions |
ISO EXP |
Streptozocin results in increased phosphorylation of SMAD2 protein [Streptozocin co-treated with Resveratrol co-treated with Ramipril] results in decreased phosphorylation of SMAD2 protein; Resveratrol inhibits the reaction [Streptozocin results in increased phosphorylation of SMAD2 protein] [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased phosphorylation of SMAD2 protein]; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased phosphorylation of SMAD2 protein |
CTD |
PMID:21300041 PMID:31062909 PMID:38282657 |
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NCBI chr18:76,369,898...76,444,819
Ensembl chr18:76,374,651...76,444,034
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G |
Smad3 |
SMAD family member 3 |
multiple interactions increases phosphorylation |
ISO EXP |
resveratrol inhibits the reaction [Streptozocin results in increased phosphorylation of SMAD3 protein] [fatostatin co-treated with Streptozocin] results in increased phosphorylation of SMAD3 protein; [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased phosphorylation of SMAD3 protein]; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased phosphorylation of SMAD3 protein |
CTD |
PMID:21300041 PMID:29420703 PMID:38282657 |
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NCBI chr 9:63,554,048...63,665,276
Ensembl chr 9:63,554,049...63,665,276
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G |
Smad4 |
SMAD family member 4 |
multiple interactions increases expression decreases expression |
ISO EXP |
Trientine inhibits the reaction [Streptozocin results in increased expression of SMAD4 mRNA] Streptozocin results in increased expression of SMAD4 mRNA; Streptozocin results in increased expression of SMAD4 protein SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of SMAD4 mRNA] |
CTD |
PMID:16973718 PMID:18246672 PMID:27629361 |
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NCBI chr18:73,767,861...73,836,862
Ensembl chr18:73,772,080...73,836,851
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G |
Smad6 |
SMAD family member 6 |
increases expression |
ISO |
Streptozocin results in increased expression of SMAD6 protein |
CTD |
PMID:17437042 |
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NCBI chr 9:63,860,358...63,929,374
Ensembl chr 9:63,860,358...63,929,341
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G |
Smad7 |
SMAD family member 7 |
affects expression decreases expression |
ISO |
Streptozocin affects the expression of SMAD7 mRNA; Streptozocin affects the expression of SMAD7 protein Streptozocin results in decreased expression of SMAD7 mRNA |
CTD |
PMID:17437042 PMID:32959695 |
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NCBI chr18:75,500,436...75,529,006
Ensembl chr18:75,500,600...75,529,006
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G |
Smpd1 |
sphingomyelin phosphodiesterase 1, acid lysosomal |
decreases response to substance |
EXP |
SMPD1 gene mutant form results in decreased susceptibility to Streptozocin |
CTD |
PMID:32481596 |
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NCBI chr 7:105,203,567...105,207,596
Ensembl chr 7:105,203,567...105,207,596
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G |
Snap23 |
synaptosomal-associated protein 23 |
multiple interactions |
ISO |
[Streptozocin co-treated with Niacinamide] results in decreased expression of SNAP23 mRNA; resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of SNAP23 mRNA] |
CTD |
PMID:25999625 |
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NCBI chr 2:120,398,137...120,436,829
Ensembl chr 2:120,398,152...120,431,736
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G |
Sncb |
synuclein, beta |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of SNCB mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of SNCB mRNA] |
CTD |
PMID:33484791 |
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NCBI chr13:54,906,673...54,914,435
Ensembl chr13:54,906,673...54,914,408
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G |
Sncg |
synuclein, gamma |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of SNCG mRNA vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of SNCG mRNA] |
CTD |
PMID:16684804 |
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NCBI chr14:34,092,231...34,096,626
Ensembl chr14:34,092,231...34,096,746
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G |
Snord15a |
small nucleolar RNA, C/D box 15A |
increases expression |
EXP |
Streptozocin results in increased expression of SNORD15A mRNA |
CTD |
PMID:27629361 |
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NCBI chr 7:99,131,992...99,132,139
Ensembl chr 7:99,131,992...99,132,139
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G |
Snord49a |
small nucleolar RNA, C/D box 49A |
increases expression |
EXP |
Streptozocin results in increased expression of SNORD49A mRNA |
CTD |
PMID:27629361 |
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NCBI chr11:62,494,286...62,494,347
Ensembl chr11:62,494,276...62,494,347
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G |
Snx12 |
sorting nexin 12 |
multiple interactions decreases expression |
ISO |
[Antagomirs results in decreased expression of MIR140 mRNA] inhibits the reaction [Streptozocin results in decreased expression of SNX12 protein]; Isoflurane promotes the reaction [Streptozocin results in decreased expression of SNX12 protein] |
CTD |
PMID:32062618 |
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NCBI chr X:100,132,973...100,266,185
Ensembl chr X:100,141,392...100,266,169
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G |
Socs3 |
suppressor of cytokine signaling 3 |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of SOCS3 protein rosiglitazone inhibits the reaction [Streptozocin results in decreased expression of SOCS3 protein] |
CTD |
PMID:21599458 |
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NCBI chr11:117,856,905...117,860,192
Ensembl chr11:117,856,905...117,860,873
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G |
Sod1 |
superoxide dismutase 1, soluble |
increases expression multiple interactions decreases activity affects expression decreases expression |
EXP ISO |
Streptozocin results in increased expression of SOD1 mRNA [Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SOD1 protein]; [Resveratrol co-treated with Streptozocin] results in decreased expression of and results in decreased activity of SOD1 protein; [Resveratrol co-treated with Streptozocin] results in decreased expression of SOD1 mRNA; [Streptozocin co-treated with bisphenol A] results in decreased expression of SOD1 protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of SOD1 protein; [Streptozocin co-treated with Niacinamide] results in increased expression of SOD1 protein; allyl methyl sulfide inhibits the reaction [Streptozocin results in decreased activity of SOD1 protein]; arjunolic acid inhibits the reaction [Streptozocin results in decreased activity of SOD1 protein]; Dimethyl Fumarate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SOD1 protein]; Dronabinol promotes the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of SOD1 protein]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SOD1 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SOD1 protein]; nifuroxazide inhibits the reaction [Streptozocin results in decreased activity of SOD1 protein]; Plant Extracts inhibits the reaction [Streptozocin results in decreased expression of SOD1 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of SOD1 protein]; Streptozocin results in decreased expression of and results in decreased activity of SOD1 protein; Trientine inhibits the reaction [Streptozocin results in decreased expression of and results in decreased activity of SOD1 protein]; Trientine inhibits the reaction [Streptozocin results in decreased expression of SOD1 protein] Streptozocin affects the expression of SOD1 mRNA 2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of SOD1 protein]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of SOD1 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of SOD1 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of SOD1 protein; [Streptozocin co-treated with Niacinamide] results in decreased activity of SOD1 protein; Berberine inhibits the reaction [Streptozocin affects the expression of SOD1 mRNA]; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SOD1 protein]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SOD1 mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of SOD1 protein]; Quercetin inhibits the reaction [Streptozocin results in decreased expression of SOD1 protein]; sulforaphane inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SOD1 mRNA]; sulforaphane inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SOD1 protein] Streptozocin results in decreased expression of SOD1 mRNA; Streptozocin results in decreased expression of SOD1 protein SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of CITED2 mRNA]; SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of ETS1 mRNA]; SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of MEF2C mRNA]; SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of MIR27A mRNA]; SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of MIR322 mRNA]; SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of SMAD4 mRNA]; SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of ZEB2 mRNA]; SOD1 protein inhibits the reaction [Streptozocin results in increased expression of MIR142 mRNA]; SOD1 protein inhibits the reaction [Streptozocin results in increased expression of MIR144 mRNA]; SOD1 protein inhibits the reaction [Streptozocin results in increased expression of MIR448 mRNA] |
CTD |
PMID:15298345 PMID:18583417 PMID:19634143 PMID:20053369 PMID:20654064 PMID:22775417 PMID:23786522 PMID:24707343 PMID:24927960 PMID:25037167 PMID:25905778 PMID:26887929 PMID:27629361 PMID:29606028 PMID:30318971 PMID:31081965 PMID:33359794 PMID:35085591 PMID:35187753 PMID:35442559 PMID:36999408 PMID:37120126 PMID:37482253 More...
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NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217
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G |
Sod2 |
superoxide dismutase 2, mitochondrial |
increases expression multiple interactions decreases response to substance affects expression decreases expression decreases activity |
EXP ISO |
Streptozocin results in increased expression of SOD2 mRNA [Ascorbic Acid co-treated with Vitamin E co-treated with beta Carotene co-treated with Copper] inhibits the reaction [Streptozocin results in decreased expression of SOD2 mRNA]; [Ascorbic Acid co-treated with Vitamin E co-treated with beta Carotene co-treated with Copper] inhibits the reaction [Streptozocin results in decreased expression of SOD2 protein]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of SOD2 mRNA; [Streptozocin co-treated with Cholesterol, Dietary] results in decreased expression of SOD2 protein; arjunolic acid inhibits the reaction [Streptozocin results in decreased activity of SOD2 protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Cholesterol, Dietary] results in decreased expression of SOD2 protein]; idebenone inhibits the reaction [Streptozocin results in decreased expression of SOD2 protein]; INS protein promotes the reaction [Streptozocin results in decreased activity of SOD2 protein]; Plant Extracts inhibits the reaction [Streptozocin results in decreased expression of and results in decreased activity of SOD2 protein]; Streptozocin results in decreased expression of and results in decreased activity of SOD2 protein; STUB1 inhibits the reaction [Streptozocin results in decreased expression of SOD2 protein]; Thioctic Acid inhibits the reaction [Streptozocin results in decreased activity of SOD2 protein]; Trientine inhibits the reaction [Streptozocin results in decreased expression of SOD2 protein] CAT protein promotes the reaction [SOD2 protein results in decreased susceptibility to Streptozocin]; SOD2 protein promotes the reaction [CAT protein results in decreased susceptibility to Streptozocin] [Dietary Fats co-treated with Streptozocin] results in decreased expression of SOD2 mRNA; [Streptozocin co-treated with INS1 protein co-treated with Glutathione] affects the expression of SOD2 mRNA; Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of SOD2 protein]; Berberine inhibits the reaction [Streptozocin affects the expression of SOD2 mRNA]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SOD2 mRNA]; Physostigmine inhibits the reaction [Streptozocin results in decreased expression of SOD2 protein]; Quercetin inhibits the reaction [Streptozocin results in decreased expression of SOD2 protein]; SIRT1 protein inhibits the reaction [Streptozocin results in decreased expression of SOD2 protein]; SIRT1 protein inhibits the reaction [Streptozocin results in decreased expression of SOD2]; SOD2 protein inhibits the reaction [Streptozocin results in increased phosphorylation of MAPT protein] Streptozocin results in decreased expression of SOD2; Streptozocin results in decreased expression of SOD2 protein Streptozocin results in decreased expression of SOD2 mRNA; Streptozocin results in decreased expression of SOD2 protein |
CTD |
PMID:14871415 PMID:15298345 PMID:15855331 PMID:18779489 PMID:19634143 PMID:19951573 PMID:20053369 PMID:20654064 PMID:20976160 PMID:21778425 PMID:21799698 PMID:22744176 PMID:22775417 PMID:22940631 PMID:25362599 PMID:25905778 PMID:26887929 PMID:28499986 PMID:33359794 PMID:34175429 PMID:35442559 PMID:35786680 More...
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NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950
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G |
Sod3 |
superoxide dismutase 3, extracellular |
multiple interactions decreases expression |
ISO EXP |
cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SOD3 protein]; tin mesoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SOD3 protein]]; Trientine inhibits the reaction [Streptozocin results in decreased expression of SOD3 mRNA]; Trientine inhibits the reaction [Streptozocin results in decreased expression of SOD3 protein] Streptozocin results in decreased expression of SOD3 mRNA; Streptozocin results in decreased expression of SOD3 protein [Streptozocin results in decreased activity of SOD3 protein] which results in increased chemical synthesis of Peroxynitrous Acid; [Streptozocin results in decreased activity of SOD3 protein] which results in increased chemical synthesis of Superoxides; Copper inhibits the reaction [Streptozocin results in decreased activity of SOD3 protein]; INS protein inhibits the reaction [Streptozocin results in decreased activity of SOD3 protein]; SOD3 gene mutant form promotes the reaction [Streptozocin results in increased chemical synthesis of Superoxides]; Streptozocin results in increased expression of and results in decreased activity of SOD3 protein |
CTD |
PMID:15821039 PMID:16973718 PMID:23884884 |
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NCBI chr 5:52,521,146...52,527,080
Ensembl chr 5:52,521,133...52,528,760
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G |
Sord |
sorbitol dehydrogenase |
multiple interactions increases expression increases glycation |
ISO |
Streptozocin results in decreased expression of and results in decreased activity of SORD protein Streptozocin results in increased expression of SORD mRNA Streptozocin results in increased glycation of SORD protein |
CTD |
PMID:8761460 |
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NCBI chr 2:122,065,320...122,095,818
Ensembl chr 2:122,065,230...122,095,821
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G |
Sort1 |
sortilin 1 |
decreases expression |
EXP |
Streptozocin results in decreased expression of SORT1 protein |
CTD |
PMID:25805502 |
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NCBI chr 3:108,191,272...108,268,835
Ensembl chr 3:108,191,398...108,268,827
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G |
Sox11 |
SRY (sex determining region Y)-box 11 |
decreases expression |
ISO |
Streptozocin results in decreased expression of SOX11 mRNA; Streptozocin results in decreased expression of SOX11 protein |
CTD |
PMID:32935389 |
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NCBI chr12:27,384,267...27,392,717
Ensembl chr12:27,384,263...27,392,573
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G |
Spag9 |
sperm associated antigen 9 |
decreases expression |
ISO |
Streptozocin results in decreased expression of SPAG9 mRNA |
CTD |
PMID:25905778 |
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NCBI chr11:93,886,794...94,016,919
Ensembl chr11:93,886,917...94,016,911
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G |
Sparc |
secreted acidic cysteine rich glycoprotein |
increases expression |
EXP |
Streptozocin results in increased expression of SPARC mRNA; Streptozocin results in increased expression of SPARC protein |
CTD |
PMID:12660331 |
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NCBI chr11:55,284,985...55,310,906
Ensembl chr11:55,285,326...55,314,009
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G |
Sphk1 |
sphingosine kinase 1 |
increases expression |
EXP ISO |
Streptozocin results in increased expression of SPHK1 Streptozocin results in increased expression of SPHK1 mRNA; Streptozocin results in increased expression of SPHK1 protein |
CTD |
PMID:19657322 PMID:21998146 |
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NCBI chr11:116,421,662...116,427,502
Ensembl chr11:116,421,751...116,427,501
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G |
Spmip11 |
sperm microtubule inner protein 11 |
multiple interactions increases secretion decreases expression |
ISO |
[Streptozocin co-treated with Fructose] results in decreased expression of NPHS1 mRNA; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in decreased expression of NPHS1 mRNA]; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in decreased expression of NPHS1 mRNA]; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in decreased expression of NPHS1 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in decreased expression of NPHS1 mRNA]; Mycophenolic Acid inhibits the reaction [Streptozocin results in decreased expression of NPHS1 mRNA]; Mycophenolic Acid inhibits the reaction [Streptozocin results in decreased expression of NPHS1 protein]; procyanidin B2 inhibits the reaction [Streptozocin results in increased expression of NPHS1 mRNA]; procyanidin B2 inhibits the reaction [Streptozocin results in increased expression of NPHS1 protein]; stannous mesoporphyrin inhibits the reaction [4-(4-(3-adamantan-1-ylureido)cyclohexyloxy)benzoic acid inhibits the reaction [Streptozocin results in increased secretion of NPHS1 protein]]; Valsartan inhibits the reaction [Streptozocin results in decreased expression of NPHS1 mRNA]; Valsartan inhibits the reaction [Streptozocin results in decreased expression of NPHS1 protein] Streptozocin results in decreased expression of NPHS1 mRNA; Streptozocin results in decreased expression of NPHS1 protein |
CTD |
PMID:17624267 PMID:20547220 PMID:23611540 PMID:25199697 PMID:30551545 |
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NCBI chr15:98,468,885...98,487,469
Ensembl chr15:98,468,885...98,487,461
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G |
Spp1 |
secreted phosphoprotein 1 |
multiple interactions increases expression |
ISO |
pioglitazone inhibits the reaction [Streptozocin results in increased expression of SPP1 mRNA]; pioglitazone inhibits the reaction [Streptozocin results in increased expression of SPP1 protein]; vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of SPP1 mRNA] Streptozocin results in increased expression of SPP1 mRNA; Streptozocin results in increased expression of SPP1 protein |
CTD |
PMID:16684804 PMID:16979161 PMID:16980342 |
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NCBI chr 5:104,582,977...104,588,919
Ensembl chr 5:104,582,984...104,588,916
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G |
Sprr2a1 |
small proline-rich protein 2A1 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of SPRR2A1 mRNA |
CTD |
PMID:33484791 |
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NCBI chr 3:92,123,142...92,129,798
Ensembl chr 3:92,123,106...92,129,218
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G |
Sprr2a2 |
small proline-rich protein 2A2 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of SPRR2A2 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of SPRR2A2 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of SPRR2A2 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 3:92,157,982...92,164,610
Ensembl chr 3:92,123,227...92,164,031
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G |
Spsb4 |
splA/ryanodine receptor domain and SOCS box containing 4 |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of SPSB4 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 9:96,825,535...96,900,408
Ensembl chr 9:96,825,535...96,900,896
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G |
Sqstm1 |
sequestosome 1 |
multiple interactions increases expression |
EXP ISO |
bafilomycin A1 inhibits the reaction [Resveratrol inhibits the reaction [Streptozocin results in increased expression of SQSTM1 protein]]; HU 308 inhibits the reaction [Streptozocin results in increased expression of SQSTM1 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of SQSTM1 protein]; Streptozocin promotes the reaction [bafilomycin A1 results in increased expression of SQSTM1 protein] [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of SQSTM1 protein; [Dietary Fats co-treated with Streptozocin] results in increased expression of SQSTM1 protein |
CTD |
PMID:24889822 PMID:30459625 PMID:35786680 |
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NCBI chr11:50,090,979...50,105,303
Ensembl chr11:50,090,193...50,101,654
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G |
Srd5a1 |
steroid 5 alpha-reductase 1 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of SRD5A1 mRNA |
CTD |
PMID:29127188 |
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NCBI chr13:69,721,568...69,759,611
Ensembl chr13:69,721,568...69,759,561
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G |
Srebf1 |
sterol regulatory element binding transcription factor 1 |
multiple interactions increases expression decreases expression increases expression |
ISO EXP |
[[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in decreased expression of SREBF1 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of SREBF1 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of SREBF1 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of SREBF1 protein; [Streptozocin co-treated with Cadmium] results in increased expression of SREBF1 protein; Allopurinol inhibits the reaction [Streptozocin results in increased expression of SREBF1 mRNA]; Allopurinol inhibits the reaction [Streptozocin results in increased expression of SREBF1 protein]; Fungal Polysaccharides inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SREBF1 mRNA]; Fungal Polysaccharides inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SREBF1 protein]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SREBF1 mRNA]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SREBF1 protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of SREBF1 protein]; Quercetin inhibits the reaction [Streptozocin results in increased expression of SREBF1 mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of SREBF1 protein] Streptozocin results in increased expression of SREBF1 mRNA; Streptozocin results in increased expression of SREBF1 protein Streptozocin results in decreased expression of SREBF1 protein [Dietary Fats co-treated with Streptozocin] results in decreased expression of SREBF1 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of SREBF1 mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of SREBF1 mRNA; Acrylamide inhibits the reaction [Streptozocin results in increased expression of SREBF1 mRNA]; fatostatin inhibits the reaction [Streptozocin results in increased expression of SREBF1 protein]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SREBF1 mRNA]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SREBF1 mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SREBF1 mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of SREBF1 mRNA] streptozocin increases expression of Srebf1 protein in liver |
CTD RGD |
PMID:22031849 PMID:23647015 PMID:25240712 PMID:28822685 PMID:29420703 PMID:29988851 PMID:31100278 PMID:33359794 PMID:33812996 PMID:34896238 PMID:35786680 PMID:39047806 PMID:32535406 More...
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RGD:401850547 |
NCBI chr11:60,089,910...60,113,407
Ensembl chr11:60,089,915...60,113,407
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G |
Srebf2 |
sterol regulatory element binding factor 2 |
multiple interactions increases expression |
ISO EXP |
[[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in decreased expression of SREBF2 mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of SREBF2 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of SREBF2 mRNA; [Streptozocin co-treated with Cadmium] results in increased expression of SREBF2 protein; Allopurinol inhibits the reaction [Streptozocin results in increased expression of SREBF2 mRNA]; Allopurinol inhibits the reaction [Streptozocin results in increased expression of SREBF2 protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of SREBF2 protein]; Quercetin inhibits the reaction [Streptozocin results in increased expression of SREBF2 mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of SREBF2 protein] Streptozocin results in increased expression of SREBF2 mRNA; Streptozocin results in increased expression of SREBF2 protein Acrylamide inhibits the reaction [Streptozocin results in increased expression of SREBF2 mRNA]; fatostatin inhibits the reaction [Streptozocin results in increased expression of SREBF2 protein] |
CTD |
PMID:23647015 PMID:25240712 PMID:29420703 PMID:34896238 PMID:35786680 |
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NCBI chr15:82,031,455...82,089,580
Ensembl chr15:82,031,382...82,089,580
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G |
Srxn1 |
sulfiredoxin 1 homolog (S. cerevisiae) |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of SRXN1 mRNA; Omaveloxolone analog promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of SRXN1 mRNA]; Omaveloxolone promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of SRXN1 mRNA] |
CTD |
PMID:32410268 |
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NCBI chr 2:151,946,738...151,953,296
Ensembl chr 2:151,947,436...151,953,296
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G |
St3gal5 |
ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of ST3GAL5 mRNA vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of ST3GAL5 mRNA] |
CTD |
PMID:16684804 |
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NCBI chr 6:72,074,555...72,131,555
Ensembl chr 6:72,074,576...72,131,555
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G |
Stac3 |
SH3 and cysteine rich domain 3 |
decreases expression |
ISO |
Streptozocin results in decreased expression of STAC3 mRNA |
CTD |
PMID:25905778 |
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NCBI chr10:127,337,505...127,344,692
Ensembl chr10:127,337,555...127,344,692
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G |
Stag3 |
STAG3 cohesin complex component |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of STAG3 mRNA |
CTD |
PMID:33484791 |
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NCBI chr 5:138,270,757...138,310,659
Ensembl chr 5:138,278,502...138,310,655
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G |
Stat3 |
signal transducer and activator of transcription 3 |
multiple interactions increases expression increases phosphorylation decreases phosphorylation |
ISO |
7-hydroxycoumarin inhibits the reaction [Streptozocin results in increased expression of STAT3 mRNA]; 7-hydroxycoumarin inhibits the reaction [Streptozocin results in increased expression of STAT3 protein]; Acetylcysteine inhibits the reaction [Streptozocin results in decreased phosphorylation of STAT3 protein]; Allopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased phosphorylation of STAT3 protein]]; Enalapril inhibits the reaction [Streptozocin results in increased expression of STAT3 mRNA]; Enalapril inhibits the reaction [Streptozocin results in increased expression of STAT3 protein]; nifuroxazide inhibits the reaction [Streptozocin results in increased phosphorylation of STAT3 protein]; Phosphocreatine inhibits the reaction [Streptozocin results in increased phosphorylation of STAT3 protein]; Propofol promotes the reaction [Streptozocin results in decreased phosphorylation of STAT3 protein]; Rosiglitazone inhibits the reaction [Streptozocin results in increased phosphorylation of STAT3 protein]; Simvastatin inhibits the reaction [Streptozocin results in increased phosphorylation of STAT3 protein] Streptozocin results in increased expression of STAT3 mRNA; Streptozocin results in increased expression of STAT3 protein |
CTD |
PMID:19958114 PMID:20821229 PMID:21599458 PMID:21912612 PMID:24810525 PMID:29291386 PMID:34455488 PMID:36650709 More...
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NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366
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G |
Stub1 |
STIP1 homology and U-Box containing protein 1 |
multiple interactions |
ISO |
STUB1 inhibits the reaction [Streptozocin results in decreased expression of AKT1 protein]; STUB1 inhibits the reaction [Streptozocin results in decreased expression of and results in decreased phosphorylation of GSK3B protein]; STUB1 inhibits the reaction [Streptozocin results in decreased expression of and results in decreased phosphorylation of NFE2L2 protein]; STUB1 inhibits the reaction [Streptozocin results in decreased expression of and results in decreased phosphorylation of PRKAA1 protein]; STUB1 inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein]; STUB1 inhibits the reaction [Streptozocin results in decreased expression of PPARGC1A protein]; STUB1 inhibits the reaction [Streptozocin results in decreased expression of SIRT1 protein]; STUB1 inhibits the reaction [Streptozocin results in decreased expression of SOD2 protein]; STUB1 inhibits the reaction [Streptozocin results in increased phosphorylation of IL1B protein]; STUB1 inhibits the reaction [Streptozocin results in increased phosphorylation of RELA protein]; STUB1 inhibits the reaction [Streptozocin results in increased phosphorylation of TNFA protein] |
CTD |
PMID:35442559 |
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NCBI chr17:26,049,608...26,051,893
Ensembl chr17:26,049,479...26,052,378
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G |
Stx4a |
syntaxin 4A (placental) |
multiple interactions |
ISO |
[Streptozocin co-treated with Niacinamide] results in decreased expression of STX4 mRNA; resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of STX4 mRNA] |
CTD |
PMID:25999625 |
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NCBI chr 7:127,439,832...127,450,160
Ensembl chr 7:127,423,466...127,448,191
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G |
Sucla2 |
succinate-Coenzyme A ligase, ADP-forming, beta subunit |
affects expression |
EXP |
Streptozocin affects the expression of SUCLA2 mRNA |
CTD |
PMID:18583417 |
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NCBI chr14:73,790,226...73,833,584
Ensembl chr14:73,762,759...73,833,582
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G |
Sult1c2 |
sulfotransferase family, cytosolic, 1C, member 2 |
multiple interactions |
ISO |
[Resveratrol co-treated with Streptozocin] results in decreased expression of SULT1C2 mRNA |
CTD |
PMID:25905778 |
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NCBI chr17:54,136,665...54,152,986
Ensembl chr17:54,136,665...54,153,367
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G |
Sult2a1 |
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 |
multiple interactions |
EXP |
[Dietary Fats co-treated with Streptozocin] results in increased expression of SULT2A1 mRNA |
CTD |
PMID:29382564 |
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NCBI chr 7:13,530,171...13,571,335
Ensembl chr 7:13,530,171...13,571,334
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G |
Sult2a3 |
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 3 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of SULT2A3 mRNA |
CTD |
PMID:33484791 |
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NCBI chr 7:13,801,480...13,856,973
Ensembl chr 7:13,801,371...13,856,969
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G |
Syp |
synaptophysin |
increases expression multiple interactions decreases expression |
EXP ISO |
Streptozocin results in increased expression of SYP mRNA Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of SYP protein]; Physostigmine inhibits the reaction [Streptozocin results in decreased expression of SYP protein]; telmisartan inhibits the reaction [Streptozocin results in decreased expression of SYP protein]; Valsartan inhibits the reaction [Streptozocin results in decreased expression of SYP protein] Streptozocin results in decreased expression of SYP mRNA; Streptozocin results in decreased expression of SYP protein fasudil inhibits the reaction [Streptozocin results in decreased expression of SYP mRNA]; fasudil inhibits the reaction [Streptozocin results in decreased expression of SYP protein]; Vitamin B 12 inhibits the reaction [Streptozocin results in decreased expression of SYP protein] |
CTD |
PMID:18487452 PMID:22062134 PMID:28499986 PMID:38049026 |
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NCBI chr X:7,504,819...7,519,495
Ensembl chr X:7,504,710...7,519,495
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G |
Syvn1 |
synovial apoptosis inhibitor 1, synoviolin |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of SYVN1 protein 4-phenylbutyric acid inhibits the reaction [Streptozocin results in decreased expression of SYVN1 protein] |
CTD |
PMID:30980806 |
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NCBI chr19:6,096,586...6,103,748
Ensembl chr19:6,096,606...6,103,742
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G |
Tac1 |
tachykinin 1 |
multiple interactions decreases expression increases expression decreases secretion |
ISO |
Botulinum Toxins, Type A inhibits the reaction [Streptozocin results in decreased expression of TAC1 protein]; Butylated Hydroxytoluene inhibits the reaction [Streptozocin results in increased expression of TAC1 mRNA]; capsazepine inhibits the reaction [Streptozocin results in decreased expression of TAC1 protein]; imirestat inhibits the reaction [Streptozocin results in decreased expression of TAC1 protein]; RN 1734 inhibits the reaction [Streptozocin results in decreased expression of TAC1 protein]; sorbinil inhibits the reaction [Streptozocin results in increased expression of TAC1 mRNA]; Streptozocin promotes the reaction [KNG1 protein modified form results in increased secretion of TAC1 protein modified form]; U 0126 inhibits the reaction [Streptozocin results in decreased expression of TAC1 protein] Streptozocin results in decreased secretion of TAC1 protein modified form |
CTD |
PMID:1374869 PMID:9748608 PMID:20832942 PMID:30583000 |
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NCBI chr 6:7,555,061...7,562,978
Ensembl chr 6:7,554,879...7,565,834
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G |
Tbc1d4 |
TBC1 domain family, member 4 |
multiple interactions |
EXP |
[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of and results in decreased phosphorylation of TBC1D4 protein; Metformin inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of TBC1D4 protein]; perilla seed oil inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of TBC1D4 protein] |
CTD |
PMID:31743741 |
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NCBI chr14:101,679,800...101,846,717
Ensembl chr14:101,679,796...101,846,627
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G |
Tedc1 |
tubulin epsilon and delta complex 1 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of TEDC1 mRNA |
CTD |
PMID:33484791 |
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NCBI chr12:113,118,639...113,135,102
Ensembl chr12:113,120,041...113,129,668
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G |
Tek |
TEK receptor tyrosine kinase |
multiple interactions increases expression decreases expression |
ISO |
baicalin inhibits the reaction [Streptozocin results in decreased expression of TEK mRNA]; Enalapril inhibits the reaction [Streptozocin results in increased expression of TEK mRNA]; Simvastatin inhibits the reaction [Streptozocin results in increased expression of TEK mRNA] Streptozocin results in increased expression of TEK mRNA; Streptozocin results in increased expression of TEK protein |
CTD |
PMID:15643138 PMID:19958114 PMID:20821229 PMID:34414639 |
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NCBI chr 4:94,627,322...94,763,213
Ensembl chr 4:94,627,526...94,763,213
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G |
Tert |
telomerase reverse transcriptase |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of TERT protein; TERT protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARGC1A protein]; TERT protein inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARA mRNA]; TERT protein inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARG mRNA]; TERT protein inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARGC1A mRNA]; TERT protein inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of TFAM mRNA] |
CTD |
PMID:39265716 |
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NCBI chr13:73,775,030...73,797,962
Ensembl chr13:73,775,030...73,797,962
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G |
Tfam |
transcription factor A, mitochondrial |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of TFAM mRNA; TERT protein inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of TFAM mRNA]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of TFAM mRNA] |
CTD |
PMID:37337224 PMID:39265716 |
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NCBI chr10:71,061,298...71,074,157
Ensembl chr10:71,061,294...71,074,110
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G |
Tfap2a |
transcription factor AP-2, alpha |
multiple interactions |
ISO EXP |
MFN2 protein mutant form inhibits the reaction [Streptozocin promotes the reaction [TFAP2A protein binds to COL4A1 promoter]]; Streptozocin promotes the reaction [TFAP2A protein binds to COL4A1 promoter] [Streptozocin co-treated with Raloxifene Hydrochloride] results in increased expression of TFAP2A protein |
CTD |
PMID:23471663 PMID:27997345 |
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NCBI chr13:40,867,278...40,891,715
Ensembl chr13:40,868,778...40,891,852
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G |
Tfrc |
transferrin receptor |
multiple interactions increases expression |
ISO |
iron pentacarbonyl inhibits the reaction [Streptozocin results in increased expression of TFRC mRNA] |
CTD |
PMID:22170771 |
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NCBI chr16:32,427,714...32,451,612
Ensembl chr16:32,427,738...32,451,612
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G |
Tgfb1 |
transforming growth factor, beta 1 |
increases expression multiple interactions increases secretion decreases methylation decreases expression decreases secretion |
EXP ISO |
Streptozocin results in increased expression of TGFB1 mRNA; Streptozocin results in increased expression of TGFB1 protein 2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of TGFB1 mRNA]; 2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of TGFB1 protein]; 3-((6-(2-methoxyphenyl)pyrimidin-4-yl)amino)phenyl)methane sulfonamide inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; [Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein; [fatostatin co-treated with Streptozocin] results in increased expression of TGFB1 mRNA; [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of TGFB1 protein]; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of TGFB1 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of TGFB1 protein; [Streptozocin co-treated with Niacinamide] results in increased expression of TGFB1 mRNA; [Streptozocin co-treated with Niacinamide] results in increased expression of TGFB1 protein; bisphenol A inhibits the reaction [Streptozocin results in decreased secretion of TGFB1 protein]; CEBPB protein affects the reaction [Streptozocin results in increased expression of TGFB1 protein]; Chlorpyrifos inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; Curcumin analog inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 mRNA]; KLF15 gene mutant form inhibits the reaction [CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein]]; KLF15 gene mutant form promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of TGFB1 mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of TGFB1 protein]; Rosuvastatin Calcium inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of TGFB1 mRNA]; sarpogrelate inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein]; sulforaphane inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein]; sulforaphane inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; Telmisartan inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; Valsartan inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein] Streptozocin results in increased secretion of TGFB1 protein 1-hexacosanol inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein]; 7-hydroxycoumarin inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; 7-hydroxycoumarin inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein; [Streptozocin co-treated with Cadmium] results in increased expression of TGFB1 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein; [Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of TGFB1 protein; [Streptozocin co-treated with Ramipril] results in increased expression of TGFB1 protein; [Streptozocin co-treated with Resveratrol co-treated with Ramipril] results in increased expression of TGFB1 protein; [Streptozocin co-treated with Resveratrol] results in increased expression of TGFB1 protein; ACE2 inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; Aspirin inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; baicalin inhibits the reaction [Streptozocin results in decreased expression of TGFB1 mRNA]; benazepril inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; benazepril inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; bisphenol A diglycidyl ether inhibits the reaction [Calcitriol inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]]; bisphenol A diglycidyl ether inhibits the reaction [Calcitriol inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]]; Calcitriol inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; Calcitriol inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; crocin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein]; crocin inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; crocin promotes the reaction [Quercetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein]]; danggui buxue decoction inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of TGFB1 protein]; dapagliflozin inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; dapagliflozin promotes the reaction [Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of TGFB1 protein]]; Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein]; Enalapril inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; Enalapril inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; esculetin inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; fasudil inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; fenugreek seed meal inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; fenugreek seed meal inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; Flavonoids inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; Gallic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein]; Gallic Acid inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; hesperetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein]; mangiferin inhibits the reaction [Streptozocin results in increased secretion of TGFB1 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of TGFB1 protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of TGFB1 protein]; nifuroxazide inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; Plant Extracts inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein]; Pyridoxamine inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; Quercetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein]; Quercetin promotes the reaction [crocin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein]]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; sulbutiamine inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; Thioctic Acid inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; Trientine inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; Tropisetron inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; Vitamin E inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; XLF-III-43 inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; Zinc inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; zingerone inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein] Streptozocin results in increased expression of TGFB1; Streptozocin results in increased expression of TGFB1 mRNA; Streptozocin results in increased expression of TGFB1 protein [ALPK1 protein results in increased susceptibility to Streptozocin] which results in increased expression of TGFB1 mRNA; [ALPK1 protein results in increased susceptibility to Streptozocin] which results in increased expression of TGFB1 protein Streptozocin results in decreased methylation of TGFB1 promoter |
CTD |
PMID:11798641 PMID:12660331 PMID:14586741 PMID:15309289 PMID:16409969 PMID:16523407 PMID:16859672 PMID:16973718 PMID:16980342 PMID:17437042 PMID:18246672 PMID:19895808 PMID:19960420 PMID:20844835 PMID:21300041 PMID:21381899 PMID:21450970 PMID:23376009 PMID:23611540 PMID:23733546 PMID:24707343 PMID:24877639 PMID:24967692 PMID:25057273 PMID:25240712 PMID:26341651 PMID:27097221 PMID:27542954 PMID:28700904 PMID:28904557 PMID:29266779 PMID:29291386 PMID:29331653 PMID:29409856 PMID:29420703 PMID:29953732 PMID:29988851 PMID:30551545 PMID:31009641 PMID:31062909 PMID:31323227 PMID:31696645 PMID:31726037 PMID:32469605 PMID:33021114 PMID:33387473 PMID:33524429 PMID:33631230 PMID:34310909 PMID:34414639 PMID:34922902 PMID:35051763 PMID:36650709 PMID:37120126 PMID:37224990 PMID:37352119 PMID:38282657 PMID:39047806 More...
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NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
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G |
Tgfbr1 |
transforming growth factor, beta receptor I |
multiple interactions increases expression affects expression |
ISO EXP |
benazepril inhibits the reaction [Streptozocin results in increased expression of TGFBR1 mRNA]; benazepril inhibits the reaction [Streptozocin results in increased expression of TGFBR1 protein] Streptozocin results in increased expression of TGFBR1 mRNA; Streptozocin results in increased expression of TGFBR1 protein Streptozocin affects the expression of TGFBR1 mRNA fatostatin inhibits the reaction [Streptozocin results in increased expression of TGFBR1 mRNA] |
CTD |
PMID:11798618 PMID:26073000 PMID:29420703 |
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NCBI chr 4:47,353,258...47,414,926
Ensembl chr 4:47,353,222...47,414,931
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G |
Tgfbr2 |
transforming growth factor, beta receptor II |
decreases expression |
EXP |
Streptozocin results in decreased expression of TGFBR2 protein |
CTD |
PMID:15496156 |
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NCBI chr 9:115,916,763...116,004,431
Ensembl chr 9:115,913,361...116,004,428
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G |
Tgfbr3 |
transforming growth factor, beta receptor III |
multiple interactions |
ISO |
[Streptozocin co-treated with Resveratrol co-treated with Ramipril] results in decreased expression of TGFBR3 protein |
CTD |
PMID:31062909 |
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NCBI chr 5:107,254,433...107,437,495
Ensembl chr 5:107,254,436...107,437,495
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G |
Th |
tyrosine hydroxylase |
multiple interactions decreases expression |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of TH protein; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TH protein]; Vitamin B 12 inhibits the reaction [Streptozocin results in decreased expression of TH protein] |
CTD |
PMID:35085591 PMID:38049026 |
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NCBI chr 7:142,446,516...142,453,732
Ensembl chr 7:142,446,489...142,484,865
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G |
Thbd |
thrombomodulin |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of THBD mRNA |
CTD |
PMID:25905778 |
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NCBI chr 2:148,246,391...148,250,108
Ensembl chr 2:148,246,386...148,250,108
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G |
Thbs1 |
thrombospondin 1 |
multiple interactions increases expression |
ISO |
pioglitazone inhibits the reaction [Streptozocin results in increased expression of THBS1 mRNA]; pioglitazone inhibits the reaction [Streptozocin results in increased expression of THBS1 protein] Streptozocin results in increased expression of THBS1 mRNA; Streptozocin results in increased expression of THBS1 protein |
CTD |
PMID:17063547 PMID:17117553 |
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NCBI chr 2:117,942,357...117,957,614
Ensembl chr 2:117,942,357...117,957,614
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G |
Thbs2 |
thrombospondin 2 |
increases expression |
EXP |
Streptozocin results in increased expression of THBS2 protein |
CTD |
PMID:23723366 |
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NCBI chr17:14,885,762...14,914,524
Ensembl chr17:14,885,762...14,914,497
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G |
Thbs4 |
thrombospondin 4 |
multiple interactions increases expression |
ISO |
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of THBS4 mRNA] |
CTD |
PMID:16684804 |
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NCBI chr13:92,888,094...92,931,326
Ensembl chr13:92,888,098...92,931,326
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G |
Thrsp |
thyroid hormone responsive |
multiple interactions decreases expression |
ISO EXP |
Fructose inhibits the reaction [Streptozocin results in decreased expression of THRSP mRNA] [Streptozocin co-treated with Dietary Fats] results in decreased expression of THRSP mRNA |
CTD |
PMID:2177838 PMID:29127188 |
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NCBI chr 7:97,062,140...97,066,757
Ensembl chr 7:97,062,145...97,066,937
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G |
Timm8b |
translocase of inner mitochondrial membrane 8B |
affects expression |
EXP |
Streptozocin affects the expression of TIMM8B mRNA |
CTD |
PMID:18583417 |
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NCBI chr 9:50,515,227...50,516,620
Ensembl chr 9:50,515,210...50,516,620
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G |
Timp1 |
tissue inhibitor of metalloproteinase 1 |
increases expression multiple interactions increases activity decreases expression |
ISO |
Streptozocin results in increased expression of TIMP1 mRNA [Resveratrol co-treated with Streptozocin] results in increased expression of TIMP1 mRNA; Olive Oil promotes the reaction [Streptozocin results in increased activity of TIMP1 protein]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of TIMP1 mRNA] |
CTD |
PMID:18246672 PMID:25246140 PMID:25905778 PMID:32662907 |
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NCBI chr X:20,736,524...20,740,972
Ensembl chr X:20,736,405...20,740,974
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G |
Timp2 |
tissue inhibitor of metalloproteinase 2 |
increases expression multiple interactions increases activity increases secretion |
ISO EXP |
Streptozocin results in increased expression of TIMP2 mRNA; Streptozocin results in increased expression of TIMP2 protein benazepril inhibits the reaction [Streptozocin results in increased expression of TIMP2 mRNA]; benazepril inhibits the reaction [Streptozocin results in increased expression of TIMP2 protein]; Olive Oil promotes the reaction [Streptozocin results in increased activity of TIMP2 protein] Streptozocin results in increased secretion of TIMP2 protein Raloxifene Hydrochloride inhibits the reaction [Streptozocin results in increased expression of TIMP2 mRNA]; Raloxifene Hydrochloride inhibits the reaction [Streptozocin results in increased secretion of TIMP2 protein] |
CTD |
PMID:16732983 PMID:20821936 PMID:23471663 PMID:25246140 |
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NCBI chr11:118,191,887...118,246,237
Ensembl chr11:118,191,887...118,246,566
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G |
Tinag |
tubulointerstitial nephritis antigen |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of TINAG protein Trientine inhibits the reaction [Streptozocin results in increased expression of TINAG protein] |
CTD |
PMID:19634143 |
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NCBI chr 9:76,858,980...76,953,084
Ensembl chr 9:76,858,975...76,953,076
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G |
Tjp1 |
tight junction protein 1 |
multiple interactions decreases expression |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of TJP1 protein; NLRP3 protein promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of TJP1 protein]; rhodioloside inhibits the reaction [Streptozocin results in decreased expression of TJP1 protein] |
CTD |
PMID:27783111 PMID:31682803 |
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NCBI chr 7:64,945,913...65,177,629
Ensembl chr 7:64,945,913...65,177,529
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G |
Tjp2 |
tight junction protein 2 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of TJP2 protein; NLRP3 protein promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of TJP2 protein] |
CTD |
PMID:27783111 |
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NCBI chr19:24,071,860...24,202,492
Ensembl chr19:24,071,869...24,202,394
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G |
Tkt |
transketolase |
multiple interactions |
ISO |
[benphothiamine co-treated with Streptozocin] results in increased activity of TKT protein |
CTD |
PMID:12592403 |
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NCBI chr14:30,271,088...30,296,681
Ensembl chr14:30,270,316...30,296,677
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G |
Tlr3 |
toll-like receptor 3 |
multiple interactions increases expression |
ISO EXP |
TNF protein inhibits the reaction [Streptozocin results in increased expression of TLR3 mRNA] |
CTD |
PMID:20446767 |
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NCBI chr 8:45,848,702...45,864,112
Ensembl chr 8:45,848,702...45,864,117
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G |
Tlr4 |
toll-like receptor 4 |
multiple interactions increases expression |
ISO EXP |
TNF protein inhibits the reaction [Streptozocin results in increased expression of TLR4 mRNA] [Dietary Fats co-treated with Streptozocin] results in increased expression of TLR4 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of TLR4 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of TLR4 protein; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TLR4 mRNA]; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TLR4 protein]; esculetin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TLR4 mRNA]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TLR4 mRNA] Streptozocin results in increased expression of TLR4 mRNA; Streptozocin results in increased expression of TLR4 protein crocin inhibits the reaction [Streptozocin results in increased expression of TLR4 protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of TLR4 protein]; myrtenol inhibits the reaction [Streptozocin results in increased expression of TLR4 mRNA]; sulbutiamine inhibits the reaction [Streptozocin results in increased expression of TLR4 protein]; Tropisetron inhibits the reaction [Streptozocin results in increased expression of TLR4 protein] |
CTD |
PMID:20446767 PMID:27769711 PMID:29409856 PMID:34477272 PMID:34610774 PMID:36504472 PMID:37224990 PMID:37482253 More...
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NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521
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G |
Tmed3 |
transmembrane p24 trafficking protein 3 |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of TMED3 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 9:89,581,256...89,587,096
Ensembl chr 9:89,581,259...89,587,121
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G |
Tmem181c-ps |
transmembrane protein 181C, pseudogene |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of TMEM181C-PS mRNA |
CTD |
PMID:33484791 |
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NCBI chr17:6,877,502...6,888,324
Ensembl chr17:6,881,152...6,907,189
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G |
Tmsb10 |
thymosin beta 10 |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of TMSB10 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 6:72,934,330...72,935,731
Ensembl chr 6:72,934,330...72,935,731
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G |
Tnf |
tumor necrosis factor |
multiple interactions increases expression increases secretion decreases expression |
ISO EXP |
PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; TNF protein inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]; TNF protein inhibits the reaction [Streptozocin results in increased expression of TLR3 mRNA]; TNF protein inhibits the reaction [Streptozocin results in increased expression of TLR4 mRNA]; TNF protein inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; TNF protein inhibits the reaction [Streptozocin results in increased expression of TNFRSF1B mRNA] 2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of TNF mRNA]; 2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of TNF protein]; 3-((6-(2-methoxyphenyl)pyrimidin-4-yl)amino)phenyl)methane sulfonamide inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; [Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of TNF protein; [Dietary Fats co-treated with Streptozocin] results in increased expression of TNF mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of TNF protein; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of TNF mRNA; [Streptozocin co-treated with bisphenol A] results in increased expression of TNF mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of TNF mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of TNF mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein; [Streptozocin co-treated with Dietary Fats] results in increased secretion of TNF protein; [Streptozocin co-treated with Niacinamide] results in increased expression of TNF mRNA; [Streptozocin co-treated with Niacinamide] results in increased expression of TNF protein; [Streptozocin co-treated with octylphenol] results in increased expression of TNF mRNA; [Streptozocin co-treated with Particulate Matter] results in increased expression of TNF protein; [Streptozocin co-treated with Vehicle Emissions] results in increased expression of TNF protein; Acrylamide inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; Alendronate inhibits the reaction [Streptozocin results in increased expression of TNF protein]; AM6545 inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; AM6545 inhibits the reaction [Streptozocin results in increased expression of TNF protein]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in increased expression of TNF protein]]; Ascorbic Acid inhibits the reaction [Streptozocin results in increased expression of TNF protein]; asiatic acid inhibits the reaction [Streptozocin results in increased expression of TNF protein]; asiatic acid promotes the reaction [Carnosine inhibits the reaction [Streptozocin results in increased expression of TNF protein]]; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased secretion of TNF protein]; Carnosine inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Carnosine promotes the reaction [asiatic acid inhibits the reaction [Streptozocin results in increased expression of TNF protein]]; Curcumin analog inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; Donepezil inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Dronabinol inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; esculetin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TNF mRNA]; esculetin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TNF protein]; etiron promotes the reaction [Streptozocin results in increased expression of TNF protein]; Genistein inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of TNF protein]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TNF mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of TNF mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of TNF protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of TNF protein]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; montelukast inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Perindopril inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; Perindopril inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in increased expression of TNF protein]]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of TNF mRNA]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF mRNA]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein]; Sodium Selenite inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; sulforaphane inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein] Streptozocin results in increased expression of TNF mRNA; Streptozocin results in increased expression of TNF protein Streptozocin results in increased secretion of TNF protein Streptozocin results in decreased expression of TNF protein 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; 4-methyl-2-((2-methylbenzyl) amino)-1,3-thiazole-5-carboxylic acid inhibits the reaction [Streptozocin results in increased expression of TNF protein]; 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TNF protein]; 7-hydroxycoumarin inhibits the reaction [Streptozocin results in increased expression of TNF protein]; [Dietary Fats co-treated with Streptozocin co-treated with Quercetin] affects the expression of TNF mRNA; [Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in increased expression of TNF protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of TNF mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of TNF protein; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of TNF protein; [Niacinamide co-treated with Streptozocin] results in increased expression of TNF protein; [pimagedine co-treated with Fatty Acids, Omega-3] inhibits the reaction [Streptozocin results in increased expression of and results in increased secretion of TNF protein]; [Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein; [Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of TNF protein; [Streptozocin co-treated with Fructose] results in increased expression of TNF protein; [Streptozocin co-treated with Niacinamide] results in increased expression of TNF protein; [Streptozocin co-treated with Sodium Glutamate] results in increased expression of TNF protein; [Telmisartan co-treated with Aspirin] inhibits the reaction [Streptozocin results in increased expression of TNF protein]; [Vanadium co-treated with Selenium co-treated with Vitamin E co-treated with Chromium] inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Acetates inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [Streptozocin results in increased expression of TNF protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Aspirin inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Atorvastatin inhibits the reaction [Streptozocin results in increased expression of TNF protein]; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of TNF protein]; caffeic acid phenethyl ester inhibits the reaction [Streptozocin results in increased expression of TNF protein]; caryophyllene inhibits the reaction [Streptozocin results in increased expression of TNF protein]; chromium nicotinic acid complex inhibits the reaction [Streptozocin results in increased secretion of TNF protein]; cloricromen inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of TNF protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of TNF protein]; dapagliflozin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TNF protein]; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of TNF protein]; dapagliflozin promotes the reaction [Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of TNF protein]]; Diosgenin inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; Diosgenin inhibits the reaction [Streptozocin results in increased expression of TNF protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein]; Enalapril inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; Fungal Polysaccharides inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TNF mRNA]; Fungal Polysaccharides inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TNF protein]; Gallic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein]; Gliclazide inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in increased expression of TNF protein]; Gliclazide inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of TNF protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; Glyburide inhibits the reaction [Streptozocin results in increased expression of TNF protein]; hesperetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein]; Ibuprofen inhibits the reaction [Streptozocin results in increased expression of TNF protein]; IGF2R protein modified form promotes the reaction [Streptozocin results in increased expression of TNF protein]; Insulin promotes the reaction [Ozone inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of TNF protein]; mangiferin inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Melatonin inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Memantine inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of TNF protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; Metformin inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in increased expression of TNF protein]]; morin analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein]; myrtenol inhibits the reaction [Streptozocin results in increased expression of TNF protein]; nifuroxazide inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; Ozone inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; Pentoxifylline inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; Phycocyanin inhibits the reaction [Streptozocin results in increased expression of TNF protein]; picolinic acid inhibits the reaction [Streptozocin results in increased secretion of TNF protein]; pinitol inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of TNF protein]; piperlongumine inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; piperlongumine inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Plant Extracts inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein]; Pyridoxamine inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein]; Resveratrol inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in increased expression of TNF protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of TNF protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of TNF protein]; rhapontin inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; Rivastigmine inhibits the reaction [Streptozocin results in increased expression of TNF protein]; SMe1EC2 promotes the reaction [Streptozocin results in increased expression of TNF protein]; sodium arsenate promotes the reaction [Streptozocin results in increased expression of TNF protein]; Streptozocin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of TNF mRNA]; Streptozocin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of TNF protein]; Streptozocin results in increased expression of and results in increased secretion of TNF protein; sulbutiamine inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Thioctic Acid inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Tropisetron inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Wortmannin inhibits the reaction [Phycocyanin inhibits the reaction [Streptozocin results in increased expression of TNF protein]]; Zinc Compounds inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein]; Zinc inhibits the reaction [Streptozocin results in increased expression of TNF mRNA] |
CTD |
PMID:11357882 PMID:12123627 PMID:15309289 PMID:15862027 PMID:15892581 PMID:15975818 PMID:16129698 PMID:16336586 PMID:17167242 PMID:17589825 PMID:17854708 PMID:18789669 PMID:18999900 PMID:19133311 PMID:19279317 PMID:19682444 PMID:20053369 PMID:20223228 PMID:20307516 PMID:20446767 PMID:20643114 PMID:20665664 PMID:21439094 PMID:21439372 PMID:21457706 PMID:21912612 PMID:23147376 PMID:24333387 PMID:24508943 PMID:24513509 PMID:24707343 PMID:24760747 PMID:24781736 PMID:24854284 PMID:24877639 PMID:25541178 PMID:26341651 PMID:26614261 PMID:26748309 PMID:27702591 PMID:27769711 PMID:28259689 PMID:28700904 PMID:29127188 PMID:29233026 PMID:29291386 PMID:29988851 PMID:30144451 PMID:30184259 PMID:30481507 PMID:30551545 PMID:30611788 PMID:30642005 PMID:30802477 PMID:30817903 PMID:31009641 PMID:31081965 PMID:31100278 PMID:31323227 PMID:31726037 PMID:32554039 PMID:32662907 PMID:32805344 PMID:33524429 PMID:33631230 PMID:33639173 PMID:33724628 PMID:34039237 PMID:34391751 PMID:34477272 PMID:34610774 PMID:34656705 PMID:34896238 PMID:34922902 PMID:35085591 PMID:35305976 PMID:36462176 PMID:36504472 PMID:36510688 PMID:36547818 PMID:36650709 PMID:37044004 PMID:37120126 PMID:37224990 PMID:37482253 PMID:38084638 PMID:39047806 More...
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NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
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G |
Tnfaip1 |
tumor necrosis factor, alpha-induced protein 1 (endothelial) |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of TNFAIP1 mRNA |
CTD |
PMID:20665664 |
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NCBI chr11:78,413,676...78,427,122
Ensembl chr11:78,413,676...78,427,158
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G |
Tnfrsf11b |
tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) |
decreases expression |
ISO |
Streptozocin results in decreased expression of TNFRSF11B mRNA |
CTD |
PMID:25617479 |
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NCBI chr15:54,114,014...54,141,700
Ensembl chr15:54,114,015...54,141,880
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G |
Tnfrsf1b |
tumor necrosis factor receptor superfamily, member 1b |
multiple interactions increases expression |
ISO EXP |
TNF protein inhibits the reaction [Streptozocin results in increased expression of TNFRSF1B mRNA] |
CTD |
PMID:20446767 |
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NCBI chr 4:144,938,938...144,973,453
Ensembl chr 4:144,940,033...144,973,440
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G |
Tnfrsf8 |
tumor necrosis factor receptor superfamily, member 8 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of TNFRSF8 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of TNFRSF8 mRNA; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNFRSF8 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 4:144,993,702...145,041,734
Ensembl chr 4:144,993,707...145,041,734
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G |
Tnfrsf9 |
tumor necrosis factor receptor superfamily, member 9 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of TNFRSF9 mRNA |
CTD |
PMID:33484791 |
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NCBI chr 4:151,004,612...151,030,561
Ensembl chr 4:150,999,019...151,030,559
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G |
Tomm40 |
translocase of outer mitochondrial membrane 40 |
affects expression |
EXP |
Streptozocin affects the expression of TOMM40 mRNA |
CTD |
PMID:18583417 |
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NCBI chr 7:19,435,238...19,449,370
Ensembl chr 7:19,435,238...19,449,363
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G |
Tph2 |
tryptophan hydroxylase 2 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of TPH2 mRNA; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of TPH2 mRNA] |
CTD |
PMID:32303808 |
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NCBI chr10:114,914,546...115,020,927
Ensembl chr10:114,914,546...115,020,927
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G |
Traf6 |
TNF receptor-associated factor 6 |
multiple interactions increases expression |
ISO EXP |
Glyburide inhibits the reaction [Streptozocin results in increased expression of TRAF6 protein]; Tropisetron inhibits the reaction [Streptozocin results in increased expression of TRAF6 protein] [Streptozocin co-treated with Dietary Fats] results in increased expression of TRAF6 mRNA; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TRAF6 mRNA] |
CTD |
PMID:36504472 PMID:37482253 |
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NCBI chr 2:101,508,765...101,532,013
Ensembl chr 2:101,508,774...101,532,014
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G |
Trat1 |
T cell receptor associated transmembrane adaptor 1 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of TRAT1 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TRAT1 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr16:48,551,137...48,630,883
Ensembl chr16:48,551,137...48,592,384
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G |
Treh |
trehalase (brush-border membrane glycoprotein) |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of TREH mRNA |
CTD |
PMID:29127188 |
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NCBI chr 9:44,584,530...44,597,602
Ensembl chr 9:44,584,530...44,597,602
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G |
Trh |
thyrotropin releasing hormone |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of TRH mRNA TRH protein inhibits the reaction [Streptozocin inhibits the reaction [Blood Glucose results in increased secretion of INS1 protein]] |
CTD |
PMID:16118471 |
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NCBI chr 6:92,219,042...92,221,631
Ensembl chr 6:92,219,042...92,221,631
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G |
Trib3 |
tribbles pseudokinase 3 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of TRIB3 mRNA |
CTD |
PMID:29127188 |
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NCBI chr 2:152,179,345...152,185,980
Ensembl chr 2:152,179,342...152,185,952
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G |
Trp53 |
transformation related protein 53 |
multiple interactions increases expression |
EXP ISO |
2-amino-6-boronohexanoic acid inhibits the reaction [Streptozocin results in increased expression of TRP53 mRNA]; [Dietary Fats co-treated with Streptozocin] results in increased expression of TRP53 protein; IGF1 protein inhibits the reaction [Streptozocin results in increased expression of TRP53 protein]; NTN1 protein inhibits the reaction [Streptozocin results in increased expression of TRP53 mRNA]; SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of TRP53] Streptozocin results in increased expression of TRP53; Streptozocin results in increased expression of TRP53 mRNA; Streptozocin results in increased expression of TRP53 protein 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of TP53 protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of TP53 protein; dapagliflozin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TP53 protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of TP53 mRNA]; Glyburide inhibits the reaction [Streptozocin results in increased expression of TP53 protein]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of TP53 mRNA]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of TP53 protein]; Tropisetron inhibits the reaction [Streptozocin results in increased expression of TP53 protein] Streptozocin results in increased expression of TP53 mRNA; Streptozocin results in increased expression of TP53 protein |
CTD |
PMID:11375343 PMID:15976052 PMID:22744176 PMID:23792339 PMID:29059224 PMID:29673160 PMID:30817903 PMID:30980806 PMID:33387473 PMID:34391751 PMID:38483099 More...
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NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
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G |
Trpm4 |
transient receptor potential cation channel, subfamily M, member 4 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of TRPM4 mRNA |
CTD |
PMID:29127188 |
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NCBI chr 7:44,952,579...44,983,495
Ensembl chr 7:44,952,056...44,983,204
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G |
Trpv4 |
transient receptor potential cation channel, subfamily V, member 4 |
increases response to substance |
ISO |
TRPV4 protein results in increased susceptibility to Streptozocin |
CTD |
PMID:18234883 |
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NCBI chr 5:114,760,213...114,796,497
Ensembl chr 5:114,760,213...114,796,482
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G |
Trpv5 |
transient receptor potential cation channel, subfamily V, member 5 |
multiple interactions decreases expression |
EXP |
formononetin inhibits the reaction [Streptozocin results in decreased expression of TRPV5 mRNA] |
CTD |
PMID:35315182 |
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NCBI chr 6:41,628,595...41,658,158
Ensembl chr 6:41,629,107...41,657,703
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G |
Trpv6 |
transient receptor potential cation channel, subfamily V, member 6 |
decreases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of TRPV6 mRNA [bisphenol A co-treated with Streptozocin] results in increased expression of TRPV6 mRNA; [Ethinyl Estradiol co-treated with Streptozocin] results in increased expression of TRPV6 mRNA; formononetin inhibits the reaction [Streptozocin results in decreased expression of TRPV6 mRNA] |
CTD |
PMID:29935216 PMID:35315182 |
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NCBI chr 6:41,597,553...41,613,339
Ensembl chr 6:41,597,558...41,613,339
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G |
Try10 |
trypsin 10 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of PRSS1 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of PRSS1 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 6:41,331,039...41,334,878
Ensembl chr 6:41,331,039...41,334,848
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G |
Tsc22d1 |
TSC22 domain family, member 1 |
decreases expression |
ISO |
Streptozocin results in decreased expression of TSC22D1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr14:76,652,401...76,745,205
Ensembl chr14:76,652,401...76,745,205
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G |
Tspan8 |
tetraspanin 8 |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of TSPAN8 mRNA |
CTD |
PMID:25905778 |
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NCBI chr10:115,652,722...115,685,798
Ensembl chr10:115,652,737...115,685,798
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G |
Tspo |
translocator protein |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of TSPO mRNA |
CTD |
PMID:25905778 |
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NCBI chr15:83,447,774...83,458,404
Ensembl chr15:83,447,793...83,458,404
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G |
Ttll8 |
tubulin tyrosine ligase-like family, member 8 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of TTLL8 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of TTLL8 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr15:88,773,981...88,839,258
Ensembl chr15:88,774,836...88,838,621
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Ttr |
transthyretin |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of TTR protein Trientine inhibits the reaction [Streptozocin results in decreased expression of TTR protein] |
CTD |
PMID:19634143 |
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NCBI chr18:20,797,266...20,807,383
Ensembl chr18:20,798,337...20,807,378
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G |
Txn1 |
thioredoxin 1 |
multiple interactions |
EXP |
TXN protein inhibits the reaction [Streptozocin results in increased secretion of ALB protein] |
CTD |
PMID:17360766 |
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NCBI chr 4:57,943,373...57,956,411
Ensembl chr 4:57,943,373...57,956,411
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G |
Txnip |
thioredoxin interacting protein |
increases expression multiple interactions |
EXP ISO |
Streptozocin results in increased expression of TXNIP mRNA Allopurinol inhibits the reaction [Streptozocin results in increased expression of TXNIP mRNA]; Allopurinol inhibits the reaction [Streptozocin results in increased expression of TXNIP protein]; Quercetin inhibits the reaction [Streptozocin results in increased expression of TXNIP mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of TXNIP protein] Streptozocin results in increased expression of TXNIP mRNA; Streptozocin results in increased expression of TXNIP protein [Streptozocin co-treated with Dietary Fats] results in increased expression of TXNIP protein; aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TXNIP protein] |
CTD |
PMID:17582205 PMID:23647015 PMID:35961541 |
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NCBI chr 3:96,465,273...96,469,173
Ensembl chr 3:96,465,273...96,469,199
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G |
Txnrd1 |
thioredoxin reductase 1 |
increases expression |
ISO |
Streptozocin results in increased expression of TXNRD1 mRNA |
CTD |
PMID:12398930 |
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NCBI chr10:82,669,785...82,733,558
Ensembl chr10:82,669,785...82,733,546
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G |
Tyrobp |
TYRO protein tyrosine kinase binding protein |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of TYROBP mRNA |
CTD |
PMID:25905778 |
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NCBI chr 7:30,113,207...30,117,007
Ensembl chr 7:30,113,185...30,117,010
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G |
Uba1 |
ubiquitin-like modifier activating enzyme 1 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of UBA1 protein 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of UBA1 protein] |
CTD |
PMID:30980806 |
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NCBI chr X:20,524,660...20,549,420
Ensembl chr X:20,524,565...20,549,418
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G |
Uchl1 |
ubiquitin carboxy-terminal hydrolase L1 |
decreases expression multiple interactions increases expression |
ISO |
Streptozocin results in decreased expression of UCHL1 protein 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of UCHL1 protein] |
CTD |
PMID:30583000 PMID:30980806 |
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NCBI chr 5:66,833,464...66,844,577
Ensembl chr 5:66,833,434...66,844,577
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G |
Uchl5 |
ubiquitin carboxyl-terminal esterase L5 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of UCHL5 protein 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of UCHL5 protein] |
CTD |
PMID:30980806 |
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NCBI chr 1:143,652,993...143,683,204
Ensembl chr 1:143,653,010...143,683,204
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G |
Ucp2 |
uncoupling protein 2 (mitochondrial, proton carrier) |
multiple interactions |
EXP |
[Dietary Fats co-treated with Streptozocin] results in decreased expression of UCP2 mRNA |
CTD |
PMID:33359794 |
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NCBI chr 7:100,142,565...100,148,832
Ensembl chr 7:100,142,544...100,151,227
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G |
Ucp3 |
uncoupling protein 3 (mitochondrial, proton carrier) |
increases expression |
EXP |
Streptozocin results in increased expression of UCP3 protein |
CTD |
PMID:16306367 |
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NCBI chr 7:100,122,198...100,135,639
Ensembl chr 7:100,122,197...100,135,639
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G |
Ugt2b37 |
UDP glucuronosyltransferase 2 family, polypeptide B37 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of UGT2B37 mRNA |
CTD |
PMID:33484791 |
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NCBI chr 5:87,388,351...87,402,647
Ensembl chr 5:87,388,352...87,402,663
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G |
Uox |
urate oxidase |
affects expression |
EXP |
Streptozocin affects the expression of UOX mRNA |
CTD |
PMID:18583417 |
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NCBI chr 3:146,302,904...146,337,238
Ensembl chr 3:146,276,181...146,338,060
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G |
Uqcrb |
ubiquinol-cytochrome c reductase binding protein |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of UQCRB mRNA; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of UQCRB mRNA] |
CTD |
PMID:37337224 |
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NCBI chr13:67,048,640...67,053,414
Ensembl chr13:67,048,681...67,053,442
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G |
Uqcrc1 |
ubiquinol-cytochrome c reductase core protein 1 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of UQCRC1 protein Trientine inhibits the reaction [Streptozocin results in increased expression of UQCRC1 protein] |
CTD |
PMID:19634143 PMID:21136691 |
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NCBI chr 9:108,765,716...108,778,709
Ensembl chr 9:108,765,701...108,778,691
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G |
Usp15 |
ubiquitin specific peptidase 15 |
multiple interactions increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [NFE2L2 protein inhibits the reaction [Streptozocin results in increased expression of USP15 protein]]; MIR497 inhibits the reaction [Streptozocin results in increased expression of USP15 mRNA]; MIR497 inhibits the reaction [Streptozocin results in increased expression of USP15 protein]; NFE2L2 protein inhibits the reaction [Streptozocin results in increased expression of USP15 protein]; USP15 protein inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; USP15 protein inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein] Streptozocin results in increased expression of USP15 mRNA; Streptozocin results in increased expression of USP15 protein |
CTD |
PMID:35478295 |
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NCBI chr10:122,940,911...123,032,924
Ensembl chr10:122,940,911...123,032,900
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G |
Usp16 |
ubiquitin specific peptidase 16 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of USP16 mRNA; esculetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of USP16 mRNA] |
CTD |
PMID:28946194 |
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NCBI chr16:87,251,833...87,280,403
Ensembl chr16:87,251,591...87,280,405
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G |
Usp2 |
ubiquitin specific peptidase 2 |
increases expression |
ISO |
Streptozocin results in increased expression of USP2 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 9:43,978,318...44,006,924
Ensembl chr 9:43,978,318...44,006,924
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G |
Usp22 |
ubiquitin specific peptidase 22 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of USP22 mRNA; esculetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of USP22 mRNA] |
CTD |
PMID:28946194 |
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NCBI chr11:61,042,607...61,065,885
Ensembl chr11:61,042,611...61,065,881
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G |
Usp27x |
ubiquitin specific peptidase 27, X chromosome |
multiple interactions increases expression |
ISO |
baicalin inhibits the reaction [Streptozocin results in increased expression of USP27X protein] |
CTD |
PMID:34414639 |
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NCBI chr X:7,238,830...7,242,069
Ensembl chr X:7,237,513...7,242,069
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G |
Vamp2 |
vesicle-associated membrane protein 2 |
multiple interactions |
ISO |
[Streptozocin co-treated with Niacinamide] results in decreased expression of VAMP2 mRNA; resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of VAMP2 mRNA] |
CTD |
PMID:25999625 |
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NCBI chr11:68,979,354...68,983,207
Ensembl chr11:68,979,316...68,983,210
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G |
Vcam1 |
vascular cell adhesion molecule 1 |
multiple interactions increases expression |
ISO EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of VCAM1 mRNA; Atorvastatin inhibits the reaction [Streptozocin results in increased expression of VCAM1 mRNA]; Atorvastatin inhibits the reaction [Streptozocin results in increased expression of VCAM1 protein]; Bezafibrate inhibits the reaction [Streptozocin results in increased expression of VCAM1 mRNA]; candesartan inhibits the reaction [Streptozocin results in increased expression of VCAM1 protein]; esculetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of VCAM1 mRNA]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of VCAM1 protein]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of VCAM1 mRNA]; procyanidin B2 inhibits the reaction [Streptozocin results in increased expression of VCAM1 mRNA] Streptozocin results in increased expression of VCAM1 mRNA; Streptozocin results in increased expression of VCAM1 protein [Streptozocin co-treated with Dietary Fats] results in increased expression of VCAM1 protein; Curcumin analog inhibits the reaction [Streptozocin results in increased expression of VCAM1 mRNA]; sulforaphane inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of VCAM1 protein] |
CTD |
PMID:16129698 PMID:16139267 PMID:16979161 PMID:17589825 PMID:24707343 PMID:25199697 PMID:28700904 PMID:28946194 More...
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NCBI chr 3:115,903,669...115,923,337
Ensembl chr 3:115,903,598...115,923,337
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G |
Vcp |
valosin containing protein |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of VCP protein 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of VCP protein] |
CTD |
PMID:30980806 |
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NCBI chr 4:42,979,964...43,000,507
Ensembl chr 4:42,979,963...43,000,507
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G |
Vdac1 |
voltage-dependent anion channel 1 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of VDAC1 protein Trientine inhibits the reaction [Streptozocin results in increased expression of VDAC1 protein] |
CTD |
PMID:19634143 |
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NCBI chr11:52,251,905...52,280,224
Ensembl chr11:52,251,687...52,280,224
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G |
Vdac2 |
voltage-dependent anion channel 2 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of VDAC2 protein Trientine inhibits the reaction [Streptozocin results in increased expression of VDAC2 protein] |
CTD |
PMID:19634143 |
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NCBI chr14:21,881,629...21,895,947
Ensembl chr14:21,875,306...21,895,947
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G |
Vdr |
vitamin D (1,25-dihydroxyvitamin D3) receptor |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of VDR mRNA; Streptozocin results in decreased expression of VDR protein Calcitriol inhibits the reaction [Streptozocin results in decreased expression of VDR mRNA]; Calcitriol inhibits the reaction [Streptozocin results in decreased expression of VDR protein] |
CTD |
PMID:29953732 |
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NCBI chr15:97,752,308...97,806,177
Ensembl chr15:97,752,306...97,808,511
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G |
Vegfa |
vascular endothelial growth factor A |
multiple interactions decreases expression increases expression decreases secretion |
EXP ISO |
bisphenol A inhibits the reaction [Streptozocin results in decreased secretion of VEGFA protein]; dehydroxymethylepoxyquinomicin inhibits the reaction [Streptozocin results in increased expression of VEGFA mRNA]; dehydroxymethylepoxyquinomicin inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]; Telmisartan inhibits the reaction [Streptozocin results in increased expression of VEGFA mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of VEGFA mRNA] [Streptozocin co-treated with Cadmium] results in increased expression of VEGFA protein; ACE2 inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]; benazepril inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]; cloricromen inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of VEGFA mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]; manumycin inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]; Melatonin inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of VEGFA protein]; PD 123319 inhibits the reaction [Streptozocin results in increased expression of VEGFA mRNA]; PD 123319 inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]; procyanidin B2 inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of VEGFA mRNA]; Simvastatin inhibits the reaction [Streptozocin results in increased expression of VEGFA mRNA]; Simvastatin inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]; Taurine inhibits the reaction [Streptozocin results in decreased expression of VEGFA mRNA]; Thioctic Acid inhibits the reaction [Streptozocin results in decreased expression of VEGFA mRNA]; turmeric extract inhibits the reaction [Streptozocin results in increased expression of VEGFA mRNA]; turmeric extract inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]; Valsartan inhibits the reaction [Streptozocin results in increased expression of VEGFA mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of VEGFA protein] Streptozocin results in increased expression of VEGFA mRNA; Streptozocin results in increased expression of VEGFA protein |
CTD |
PMID:11596663 PMID:14718351 PMID:15643138 PMID:17662242 PMID:17724226 PMID:18569938 PMID:19279317 PMID:20821229 PMID:20844835 PMID:22058332 PMID:22191573 PMID:25199697 PMID:25240712 PMID:26073000 PMID:32554039 PMID:35051763 More...
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NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295
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G |
Vegfc |
vascular endothelial growth factor C |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of VEGFC mRNA baicalin inhibits the reaction [Streptozocin results in decreased expression of VEGFC mRNA] |
CTD |
PMID:34414639 |
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NCBI chr 8:54,530,567...54,639,489
Ensembl chr 8:54,530,641...54,640,131
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G |
Vim |
vimentin |
multiple interactions increases expression |
ISO |
carvedilol inhibits the reaction [Streptozocin results in increased expression of VIM protein] |
CTD |
PMID:12140129 |
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NCBI chr 2:13,579,122...13,587,637
Ensembl chr 2:13,578,738...13,587,637
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G |
Vldlr |
very low density lipoprotein receptor |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of VLDLR mRNA |
CTD |
PMID:29127188 |
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NCBI chr19:27,190,070...27,231,631
Ensembl chr19:27,193,884...27,231,631
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G |
Vnn1 |
vanin 1 |
multiple interactions |
ISO |
[Streptozocin co-treated with Fructose] results in increased expression of VNN1 mRNA; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of VNN1 mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of VNN1 mRNA] |
CTD |
PMID:30551545 |
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NCBI chr10:23,770,586...23,781,242
Ensembl chr10:23,770,586...23,781,241
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G |
Vwa3b |
von Willebrand factor A domain containing 3B |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of VWA3B mRNA |
CTD |
PMID:33484791 |
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NCBI chr 1:37,068,372...37,226,689
Ensembl chr 1:37,065,677...37,226,694
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G |
Wdr31 |
WD repeat domain 31 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of WDR31 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of WDR31 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 4:62,366,890...62,389,236
Ensembl chr 4:62,366,890...62,389,133
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G |
Wdr35 |
WD repeat domain 35 |
increases expression |
ISO |
Streptozocin results in increased expression of WDR35 mRNA |
CTD |
PMID:20224876 |
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NCBI chr12:9,023,897...9,078,848
Ensembl chr12:9,023,892...9,078,847
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G |
Wee1 |
WEE 1 homolog 1 (S. pombe) |
increases expression |
ISO |
Streptozocin results in increased expression of WEE1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 7:109,721,266...109,742,506
Ensembl chr 7:109,721,253...109,742,493
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G |
Wnt3a |
wingless-type MMTV integration site family, member 3A |
decreases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of WNT3A protein 5-Methoxypsoralen inhibits the reaction [Streptozocin results in decreased expression of WNT3A protein]; Tadalafil inhibits the reaction [Streptozocin results in decreased expression of WNT3A protein] |
CTD |
PMID:34428446 |
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NCBI chr11:59,138,859...59,181,579
Ensembl chr11:59,138,859...59,181,578
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G |
Wsb1 |
WD repeat and SOCS box-containing 1 |
decreases expression |
ISO |
Streptozocin results in decreased expression of WSB1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr11:79,130,208...79,145,521
Ensembl chr11:79,130,198...79,145,497
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G |
Xbp1 |
X-box binding protein 1 |
multiple interactions |
ISO EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of XBP1 mRNA alternative form; Bilirubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of XBP1 mRNA alternative form]; moutan cortex inhibits the reaction [Streptozocin results in increased expression of and results in increased secretion of XBP1 protein alternative form]; Streptozocin results in increased expression of and results in increased secretion of XBP1 protein alternative form [Dietary Fats co-treated with Streptozocin] results in increased splicing of XBP1 mRNA; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased splicing of XBP1 mRNA] |
CTD |
PMID:27664441 PMID:33812996 PMID:37054934 |
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NCBI chr11:5,470,641...5,475,993
Ensembl chr11:5,470,659...5,475,893
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G |
Xdh |
xanthine dehydrogenase |
multiple interactions affects activity increases expression increases activity |
ISO |
[Propolis co-treated with Chlorpyrifos co-treated with Streptozocin] results in increased activity of XDH protein modified form; [Propolis co-treated with Chlorpyrifos co-treated with Streptozocin] results in increased expression of XDH mRNA; [Streptozocin affects the activity of XDH protein] which results in increased chemical synthesis of Hydrogen Peroxide; [Streptozocin co-treated with Chlorpyrifos] inhibits the reaction [Propolis results in decreased activity of XDH protein modified form]; [Streptozocin co-treated with Chlorpyrifos] inhibits the reaction [Propolis results in decreased expression of XDH mRNA]; [Streptozocin co-treated with Chlorpyrifos] results in increased activity of XDH protein modified form; [Streptozocin co-treated with Chlorpyrifos] results in increased expression of XDH mRNA; Allopurinol inhibits the reaction [[Streptozocin affects the activity of XDH protein] which results in increased chemical synthesis of Hydrogen Peroxide]; Allopurinol inhibits the reaction [Streptozocin affects the activity of XDH protein]; Chlorpyrifos promotes the reaction [Streptozocin results in increased expression of XDH mRNA]; Propolis inhibits the reaction [[Streptozocin co-treated with Chlorpyrifos] results in increased activity of XDH protein modified form]; Propolis inhibits the reaction [[Streptozocin co-treated with Chlorpyrifos] results in increased expression of XDH mRNA]; Propolis inhibits the reaction [Streptozocin results in increased activity of XDH protein modified form]; Propolis inhibits the reaction [Streptozocin results in increased expression of XDH mRNA]; Quercetin inhibits the reaction [[Streptozocin affects the activity of XDH protein] which results in increased chemical synthesis of Hydrogen Peroxide]; Quercetin inhibits the reaction [Streptozocin affects the activity of XDH protein]; Streptozocin inhibits the reaction [Propolis results in decreased activity of XDH protein modified form]; Streptozocin inhibits the reaction [Propolis results in decreased expression of XDH mRNA]; Streptozocin promotes the reaction [Chlorpyrifos results in increased activity of XDH protein modified form]; Streptozocin promotes the reaction [Chlorpyrifos results in increased expression of XDH mRNA] Streptozocin results in increased activity of XDH protein; Streptozocin results in increased activity of XDH protein modified form |
CTD |
PMID:23647015 PMID:31400774 PMID:32812462 PMID:37354076 |
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NCBI chr17:74,190,890...74,257,191
Ensembl chr17:74,190,890...74,257,191
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G |
Xiap |
X-linked inhibitor of apoptosis |
increases expression |
ISO |
Streptozocin results in increased expression of XIAP protein |
CTD |
PMID:15976052 |
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NCBI chr X:41,148,483...41,198,541
Ensembl chr X:41,148,556...41,198,533
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G |
Zbed4-ps1 |
zinc finger, BED type containing 4, pseudogene 1 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of ZBED4-PS1 mRNA |
CTD |
PMID:33484791 |
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NCBI chr 7:13,372,832...13,376,724
Ensembl chr 7:13,373,032...13,376,497
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G |
Zcchc18 |
zinc finger, CCHC domain containing 18 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of ZCCHC18 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ZCCHC18 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr X:135,893,128...135,899,221
Ensembl chr X:135,893,904...135,899,221
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G |
Zdhhc23 |
zinc finger, DHHC domain containing 23 |
multiple interactions |
ISO |
[resveratrol co-treated with Streptozocin] results in decreased expression of ZDHHC23 mRNA |
CTD |
PMID:25905778 |
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NCBI chr16:43,785,396...43,800,295
Ensembl chr16:43,785,396...43,800,154
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G |
Zeb2 |
zinc finger E-box binding homeobox 2 |
decreases expression multiple interactions |
EXP ISO |
Streptozocin results in decreased expression of ZEB2 mRNA SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of ZEB2 mRNA] |
CTD |
PMID:27629361 |
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NCBI chr 2:44,873,523...45,007,378
Ensembl chr 2:44,873,644...45,007,407
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G |
Zfp184 |
zinc finger protein 184 (Kruppel-like) |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of ZFP184 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of ZFP184 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr13:22,129,223...22,144,961
Ensembl chr13:22,129,264...22,144,949
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G |
Zfp239 |
zinc finger protein 239 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of ZFP239 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ZFP239 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 6:117,838,907...117,849,727
Ensembl chr 6:117,839,061...117,850,252
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G |
Zpbp2 |
zona pellucida binding protein 2 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of ZPBP2 mRNA |
CTD |
PMID:33484791 |
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NCBI chr11:98,441,923...98,449,491
Ensembl chr11:98,441,923...98,449,491
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