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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:streptozocin
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Accession:CHEBI:9288 term browser browse the term
Definition:An N-nitrosourea that is an antibiotic produced by Streptomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animals.
Synonyms:exact_synonym: 2-deoxy-2-{[methyl(nitroso)carbamoyl]amino}-alpha-D-glucopyranose
 related_synonym: 2-Deoxy-2-(((methylnitrosoamino)carbonyl)amino)-D-glucopyranose;   2-Deoxy-2-(3-methyl-3-nitrosoureido)-D-glucopyranose;   Formula=C8H15N3O7;   InChI=1S/C8H15N3O7/c1-11(10-17)8(16)9-4-6(14)5(13)3(2-12)18-7(4)15/h3-7,12-15H,2H2,1H3,(H,9,16)/t3-,4-,5-,6-,7+/m1/s1;   InChIKey=ZSJLQEPLLKMAKR-GKHCUFPYSA-N;   N-D-Glucosyl-(2)-N'-nitrosomethylharnstoff;   N-D-Glucosyl-(2)-N'-nitrosomethylurea;   SMILES=CN(N=O)C(=O)N[C@H]1[C@@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O;   Streptozocinium;   Streptozotocin;   Zanosar;   estreptozocina;   streptozocine;   streptozocinum
 xref: CAS:18883-66-4;   DrugBank:DB00428;   HMDB:HMDB0014572;   KEGG:C07313;   KEGG:D05932
 xref_mesh: MESH:D013311
 xref: PMID:12613763;   PMID:23151907;   PMID:23333576;   PMID:23600389;   PMID:23612842;   PMID:23662406;   PMID:2954873;   Patent:FR1434920;   Patent:US2005271747;   Patent:US2005272738;   Patent:US2008085882;   Patent:US4156777;   Reaxys:2060675;   Wikipedia:Streptozocin



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streptozocin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of A2M mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of A2M mRNA] CTD PMID:33484791 NCBI chr 6:121,612,920...121,656,197
Ensembl chr 6:121,612,335...121,656,186
JBrowse link
G Abca1 ATP-binding cassette, sub-family A member 1 multiple interactions ISO [[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in decreased expression of ABCA1 mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of ABCA1 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of ABCA1 mRNA CTD PMID:35786680 NCBI chr 4:53,030,789...53,159,988
Ensembl chr 4:53,030,787...53,159,895
JBrowse link
G Abcb11 ATP-binding cassette, sub-family B member 11 increases activity
increases expression
ISO
EXP
Streptozocin results in increased activity of ABCB11 protein
Streptozocin results in increased expression of ABCB11 protein
CTD PMID:12055592 PMID:23319174 NCBI chr 2:69,068,626...69,172,960
Ensembl chr 2:69,068,626...69,172,958
JBrowse link
G Abcb1b ATP-binding cassette, sub-family B member 1B decreases expression
increases expression
EXP Streptozocin results in decreased expression of ABCB1B mRNA; Streptozocin results in decreased expression of ABCB1B protein
Streptozocin results in increased expression of ABCB1B protein
CTD PMID:22531820 PMID:23319174 NCBI chr 5:8,848,147...8,916,314
Ensembl chr 5:8,848,147...8,916,315
JBrowse link
G Abcb4 ATP-binding cassette, sub-family B member 4 increases expression ISO Streptozocin results in increased expression of ABCB4 mRNA; Streptozocin results in increased expression of ABCB4 protein CTD PMID:12055592 NCBI chr 5:8,943,614...9,009,226
Ensembl chr 5:8,943,717...9,009,231
JBrowse link
G Abcc1 ATP-binding cassette, sub-family C member 1 increases expression EXP Streptozocin results in increased expression of ABCC1 mRNA; Streptozocin results in increased expression of ABCC1 protein CTD PMID:22531820 PMID:23319174 NCBI chr16:14,179,317...14,292,743
Ensembl chr16:14,179,422...14,293,601
JBrowse link
G Abcc2 ATP-binding cassette, sub-family member 2 increases expression ISO
EXP
Streptozocin results in increased expression of ABCC2 mRNA
Streptozocin results in increased expression of ABCC2 mRNA; Streptozocin results in increased expression of ABCC2 protein
CTD PMID:11752103 PMID:22531820 PMID:23319174 NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179
JBrowse link
G Abcc3 ATP-binding cassette, sub-family C member 3 decreases expression
increases expression
multiple interactions
EXP
ISO
Streptozocin results in decreased expression of ABCC3 mRNA
Streptozocin results in increased expression of ABCC3 mRNA; Streptozocin results in increased expression of ABCC3 protein
[resveratrol co-treated with Streptozocin] results in increased expression of ABCC3 mRNA
CTD PMID:22531820 PMID:23319174 PMID:25905778 NCBI chr11:94,234,121...94,283,843
Ensembl chr11:94,234,121...94,283,823
JBrowse link
G Abcc4 ATP-binding cassette, sub-family C member 4 increases expression
multiple interactions
EXP Streptozocin results in increased expression of ABCC4 mRNA; Streptozocin results in increased expression of ABCC4 protein
[Dietary Fats co-treated with Streptozocin] results in increased expression of ABCC4 mRNA
CTD PMID:22531820 PMID:23319174 PMID:29382564 NCBI chr14:118,720,104...118,945,475
Ensembl chr14:118,720,104...118,943,631
JBrowse link
G Abcc5 ATP-binding cassette, sub-family C member 5 increases expression EXP Streptozocin results in increased expression of ABCC5 mRNA; Streptozocin results in increased expression of ABCC5 protein CTD PMID:22531820 PMID:23319174 NCBI chr16:20,150,053...20,245,178
Ensembl chr16:20,150,053...20,245,144
JBrowse link
G Abcc6 ATP-binding cassette, sub-family C member 6 decreases expression EXP Streptozocin results in decreased expression of ABCC6 protein CTD PMID:22531820 NCBI chr 7:45,625,804...45,679,915
Ensembl chr 7:45,616,979...45,679,726
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group) increases expression EXP Streptozocin results in increased expression of ABCG2 mRNA; Streptozocin results in increased expression of ABCG2 protein CTD PMID:23319174 NCBI chr 6:58,561,476...58,669,436
Ensembl chr 6:58,561,508...58,672,661
JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 increases expression EXP Streptozocin results in increased expression of ABCG5 mRNA CTD PMID:23319174 NCBI chr17:84,965,602...84,990,439
Ensembl chr17:84,965,662...84,990,439
JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 increases expression EXP Streptozocin results in increased expression of ABCG8 mRNA CTD PMID:23319174 NCBI chr17:84,983,730...85,007,761
Ensembl chr17:84,983,730...85,007,761
JBrowse link
G Abhd2 abhydrolase domain containing 2 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of ABHD2 mRNA CTD PMID:29127188 NCBI chr 7:78,923,002...79,015,257
Ensembl chr 7:78,922,947...79,015,256
JBrowse link
G Acaca acetyl-Coenzyme A carboxylase alpha multiple interactions
decreases expression
decreases activity
increases expression
ISO
EXP
Fructose inhibits the reaction [Streptozocin results in decreased activity of ACACA protein]; Fructose inhibits the reaction [Streptozocin results in decreased expression of ACACA mRNA]; Triiodothyronine inhibits the reaction [Streptozocin results in decreased activity of ACACA protein]; Triiodothyronine inhibits the reaction [Streptozocin results in decreased expression of ACACA mRNA]
Streptozocin results in increased expression of ACACA mRNA
[Dietary Fats co-treated with Streptozocin] results in increased expression of ACACA mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of ACACA mRNA; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of ACACA mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of ACACA mRNA]
CTD PMID:1973097 PMID:28822685 PMID:33812996 PMID:39047806 NCBI chr11:84,020,461...84,292,477
Ensembl chr11:84,020,498...84,292,477
JBrowse link
G Acadm acyl-Coenzyme A dehydrogenase, medium chain decreases expression
multiple interactions
ISO Streptozocin results in decreased expression of ACADM protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of ACADM protein]
CTD PMID:19634143 NCBI chr 3:153,627,990...153,650,280
Ensembl chr 3:153,627,994...153,650,269
JBrowse link
G Acat1 acetyl-Coenzyme A acetyltransferase 1 decreases expression
multiple interactions
ISO
EXP
Streptozocin results in decreased expression of ACAT1 protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of ACAT1 protein]
Acrylamide inhibits the reaction [Streptozocin results in decreased expression of ACAT1 mRNA]
CTD PMID:19634143 PMID:34896238 NCBI chr 9:53,491,822...53,521,650
Ensembl chr 9:53,491,822...53,521,682
JBrowse link
G Acbd6 acyl-Coenzyme A binding domain containing 6 increases expression ISO Streptozocin results in increased expression of ACBD6 mRNA CTD PMID:25905778 NCBI chr 1:155,433,845...155,564,120
Ensembl chr 1:155,433,866...155,567,076
JBrowse link
G Ace angiotensin I converting enzyme multiple interactions
increases expression
increases activity
ISO
EXP
[INS1 protein co-treated with Pravastatin] inhibits the reaction [Streptozocin results in increased expression of ACE protein]; Bezafibrate inhibits the reaction [Streptozocin results in increased expression of ACE mRNA]; Bezafibrate inhibits the reaction [Streptozocin results in increased expression of ACE protein]; Enalapril inhibits the reaction [Streptozocin results in increased expression of ACE mRNA]; Enalapril inhibits the reaction [Streptozocin results in increased expression of ACE protein]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of ACE mRNA]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of ACE protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of ACE mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of ACE mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of ACE protein]
Streptozocin results in increased expression of ACE mRNA; Streptozocin results in increased expression of ACE protein
Streptozocin results in increased activity of ACE protein
2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of ACE mRNA]; [Streptozocin co-treated with Niacinamide] results in increased expression of ACE mRNA; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of ACE protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of ACE mRNA]
CTD PMID:15793251 PMID:16979161 PMID:22191573 PMID:23733546 PMID:28468961 More... NCBI chr11:105,858,774...105,880,790
Ensembl chr11:105,858,771...105,880,790
JBrowse link
G Ace2 angiotensin converting enzyme 2 decreases expression
multiple interactions
increases activity
EXP
ISO
Streptozocin results in decreased expression of ACE2 protein
2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of ACE2 mRNA]; [Streptozocin co-treated with Niacinamide] results in decreased expression of ACE2 mRNA; CEBPB protein inhibits the reaction [Streptozocin results in decreased expression of ACE2 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of ACE2 mRNA]; Telmisartan inhibits the reaction [Streptozocin results in decreased expression of ACE2 protein]
[INS1 protein co-treated with Pravastatin] inhibits the reaction [Streptozocin results in decreased expression of ACE2 protein]; ACE2 inhibits the reaction [Streptozocin results in increased expression of AGT protein modified form]; ACE2 inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; ACE2 inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]
Streptozocin results in increased activity of ACE2 protein
CTD PMID:20844835 PMID:21381899 PMID:28468961 PMID:29266779 PMID:29682576 More... NCBI chr  X:162,922,338...162,971,414
Ensembl chr  X:162,922,328...162,971,416
JBrowse link
G Acer2 alkaline ceramidase 2 multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of ACER2 mRNA CTD PMID:25905778 NCBI chr 4:86,792,585...86,853,059
Ensembl chr 4:86,792,633...86,853,059
JBrowse link
G Ache acetylcholinesterase multiple interactions
increases activity
decreases activity
EXP
ISO
Acetylcysteine inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Alendronate inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; bisphenol A diglycidyl ether inhibits the reaction [Lisinopril inhibits the reaction [Streptozocin results in increased activity of ACHE protein]]; bisphenol A diglycidyl ether inhibits the reaction [Telmisartan inhibits the reaction [Streptozocin results in increased activity of ACHE protein]]; Curcumin inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Donepezil inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Genistein inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Indinavir inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Lisinopril inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Physostigmine inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Telmisartan inhibits the reaction [Streptozocin results in increased activity of ACHE protein]
[Fructose co-treated with Streptozocin] results in increased expression of ACHE protein; [Propolis co-treated with Chlorpyrifos co-treated with Streptozocin] results in decreased activity of ACHE protein; [Propolis co-treated with Streptozocin] inhibits the reaction [Chlorpyrifos results in decreased activity of ACHE protein]; [Streptozocin co-treated with Chlorpyrifos] results in decreased activity of ACHE protein; [Streptozocin co-treated with Dietary Fats] results in increased activity of ACHE protein; alpha-Tocopherol inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Canagliflozin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased activity of ACHE protein]; Chlorpyrifos inhibits the reaction [Streptozocin results in decreased activity of ACHE protein]; Donepezil inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; geraniol inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Melatonin inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Metformin inhibits the reaction [[Fructose co-treated with Streptozocin] results in increased expression of ACHE protein]; Phycocyanin inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Propolis inhibits the reaction [[Streptozocin co-treated with Chlorpyrifos] results in decreased activity of ACHE protein]; Propolis inhibits the reaction [Streptozocin results in decreased activity of ACHE protein]; pyrazolanthrone inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Rivastigmine inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Streptozocin inhibits the reaction [Chlorpyrifos results in decreased activity of ACHE protein]; Streptozocin promotes the reaction [[Propolis co-treated with Chlorpyrifos] results in decreased activity of ACHE protein]; Tocotrienols inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; vanillin inhibits the reaction [[Fructose co-treated with Streptozocin] results in increased expression of ACHE protein]
CTD PMID:18208924 PMID:18343489 PMID:19464315 PMID:19705549 PMID:20369229 More... NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728
JBrowse link
G Acmsd amino carboxymuconate semialdehyde decarboxylase increases activity
increases expression
ISO Streptozocin results in increased activity of ACMSD protein
Streptozocin results in increased expression of ACMSD mRNA
CTD PMID:12042425 NCBI chr 1:127,657,149...127,695,723
Ensembl chr 1:127,657,150...127,695,715
JBrowse link
G Aco2 aconitase 2, mitochondrial decreases expression
multiple interactions
ISO Streptozocin results in decreased expression of ACO2 protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of ACO2 protein]
CTD PMID:19634143 NCBI chr15:81,756,664...81,799,338
Ensembl chr15:81,756,510...81,799,334
JBrowse link
G Acot1 acyl-CoA thioesterase 1 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of ACOT1 mRNA CTD PMID:29127188 NCBI chr12:84,056,276...84,064,444
Ensembl chr12:84,056,264...84,065,145
JBrowse link
G Acot2 acyl-CoA thioesterase 2 multiple interactions ISO
EXP
[resveratrol co-treated with Streptozocin] results in decreased expression of ACOT2 mRNA
[Streptozocin co-treated with Dietary Fats] results in increased expression of ACOT2 mRNA
CTD PMID:25905778 PMID:29127188 NCBI chr12:84,034,635...84,040,651
Ensembl chr12:84,034,635...84,040,647
JBrowse link
G Acot9 acyl-CoA thioesterase 9 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of ACOT9 mRNA CTD PMID:29127188 NCBI chr  X:154,045,439...154,080,650
Ensembl chr  X:154,045,439...154,080,650
JBrowse link
G Acox1 acyl-Coenzyme A oxidase 1, palmitoyl multiple interactions ISO [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of ACOX1 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of ACOX1 mRNA CTD PMID:35786680 NCBI chr11:116,062,714...116,089,605
Ensembl chr11:116,062,714...116,089,871
JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant multiple interactions
increases activity
increases expression
EXP formononetin inhibits the reaction [Streptozocin results in increased activity of ACP5 protein]; formononetin inhibits the reaction [Streptozocin results in increased expression of ACP5 mRNA] CTD PMID:35315182 NCBI chr 9:22,038,023...22,047,042
Ensembl chr 9:22,038,023...22,047,007
JBrowse link
G Acsm2 acyl-CoA synthetase medium-chain family member 2 increases expression ISO Streptozocin results in increased expression of ACSM2 mRNA CTD PMID:25905778 NCBI chr 7:119,153,563...119,199,917
Ensembl chr 7:119,153,563...119,199,913
JBrowse link
G Acss1 acyl-CoA synthetase short-chain family member 1 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of ACSS1 mRNA CTD PMID:29127188 NCBI chr 2:150,460,031...150,510,160
Ensembl chr 2:150,460,025...150,510,420
JBrowse link
G Acta2 actin alpha 2, smooth muscle, aorta multiple interactions
increases expression
decreases expression
ISO
EXP
[Streptozocin co-treated with Fructose] results in increased expression of ACTA2 protein; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of ACTA2 protein]; Metformin promotes the reaction [dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of ACTA2 protein]]
[Dietary Fats co-treated with Streptozocin] results in increased expression of ACTA2 mRNA; [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of ACTA2 mRNA]; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of ACTA2 mRNA; [Streptozocin co-treated with fatostatin] results in increased expression of ACTA2 protein; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of ACTA2 mRNA; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of ACTA2 protein; bisphenol A inhibits the reaction [Streptozocin results in decreased expression of ACTA2 protein]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of ACTA2 mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of ACTA2 mRNA]
Streptozocin results in increased expression of ACTA2 protein
CTD PMID:29420703 PMID:29988851 PMID:30551545 PMID:35051763 PMID:35993117 More... NCBI chr19:34,217,736...34,232,985
Ensembl chr19:34,218,490...34,232,990
JBrowse link
G Actc1 actin, alpha, cardiac muscle 1 decreases expression ISO Streptozocin results in decreased expression of ACTC1 protein CTD PMID:21136691 NCBI chr 2:113,877,763...113,883,356
Ensembl chr 2:113,877,763...113,884,029
JBrowse link
G Actn4 actinin alpha 4 increases expression
multiple interactions
ISO Streptozocin results in increased expression of ACTN4 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of ACTN4 protein]
CTD PMID:19634143 NCBI chr 7:28,592,673...28,661,799
Ensembl chr 7:28,592,673...28,661,765
JBrowse link
G Acy1 aminoacylase 1 decreases expression
multiple interactions
ISO Streptozocin results in decreased expression of ACY1 protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of ACY1 protein]
CTD PMID:19634143 NCBI chr 9:106,310,180...106,315,594
Ensembl chr 9:106,310,180...106,315,518
JBrowse link
G Ada adenosine deaminase multiple interactions
increases activity
ISO [Zinc Sulfate results in increased abundance of Zinc] inhibits the reaction [Streptozocin results in increased activity of ADA protein] CTD PMID:32864810 NCBI chr 2:163,565,703...163,592,154
Ensembl chr 2:163,568,504...163,592,159
JBrowse link
G Adam17 a disintegrin and metallopeptidase domain 17 multiple interactions
increases expression
ISO Diosgenin inhibits the reaction [Streptozocin results in increased expression of ADAM17 mRNA]; Diosgenin inhibits the reaction [Streptozocin results in increased expression of ADAM17 protein]
Streptozocin results in increased expression of ADAM17 mRNA; Streptozocin results in increased expression of ADAM17 protein
CTD PMID:35305976 NCBI chr12:21,373,510...21,423,633
Ensembl chr12:21,373,510...21,423,633
JBrowse link
G Adgre1 adhesion G protein-coupled receptor E1 multiple interactions
increases expression
ISO
EXP
stannous mesoporphyrin inhibits the reaction [4-(4-(3-adamantan-1-ylureido)cyclohexyloxy)benzoic acid inhibits the reaction [Streptozocin results in increased expression of ADGRE1 protein]]
[fatostatin co-treated with Streptozocin] results in increased expression of ADGRE1 mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of ADGRE1 mRNA; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of ADGRE1 mRNA]
Streptozocin results in increased expression of ADGRE1 mRNA
CTD PMID:23611540 PMID:29420703 PMID:39047806 NCBI chr17:57,665,650...57,790,527
Ensembl chr17:57,665,691...57,790,527
JBrowse link
G Adgrg7 adhesion G protein-coupled receptor G7 multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of ADGRG7 mRNA CTD PMID:33484791 NCBI chr16:56,544,972...56,616,369
Ensembl chr16:56,544,972...56,616,218
JBrowse link
G Adh1 alcohol dehydrogenase 1 (class I) increases expression ISO Streptozocin results in increased expression of ADH1 mRNA CTD PMID:25905778 NCBI chr 3:137,983,346...137,996,459
Ensembl chr 3:137,966,752...137,996,459
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions
decreases expression
decreases secretion
ISO
EXP
1,3-dimethoxy-5-methyl-2-(3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl)benzene inhibits the reaction [4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in decreased secretion of ADIPOQ protein]]; 4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in decreased secretion of ADIPOQ protein]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of ADIPOQ protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of ADIPOQ protein; Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOQ mRNA]; Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOQ protein]; Allopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOQ mRNA]]; Allopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOQ protein]]; cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of ADIPOQ protein]; geraniol promotes the reaction [Streptozocin results in decreased expression of ADIPOQ protein]; morin analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of ADIPOQ protein]; Warfarin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of ADIPOQ protein]; Zinc Compounds inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein]
Streptozocin results in decreased expression of ADIPOQ mRNA; Streptozocin results in decreased expression of ADIPOQ protein
[Dietary Fats co-treated with Streptozocin] results in decreased expression of and results in decreased secretion of ADIPOQ protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of and results in decreased secretion of ADIPOQ protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein]; omaveloxolone analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein]
CTD PMID:17270171 PMID:21439372 PMID:21912612 PMID:22675305 PMID:24854284 More... NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778
JBrowse link
G Adipor1 adiponectin receptor 1 decreases expression
multiple interactions
increases expression
ISO Streptozocin results in decreased expression of ADIPOR1 protein
1,3-dimethoxy-5-methyl-2-(3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl)benzene inhibits the reaction [4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in increased expression of ADIPOR1 protein]]; 4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in increased expression of ADIPOR1 protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of ADIPOR1 protein]
CTD PMID:17270171 PMID:24413998 PMID:29274332 NCBI chr 1:134,343,116...134,361,089
Ensembl chr 1:134,343,116...134,361,089
JBrowse link
G Adipor2 adiponectin receptor 2 multiple interactions
decreases expression
ISO Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOR2 protein]; Allopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOR2 protein]] CTD PMID:21912612 NCBI chr 6:119,330,111...119,394,489
Ensembl chr 6:119,330,111...119,394,665
JBrowse link
G Adora2a adenosine A2a receptor increases expression EXP Streptozocin results in increased expression of ADORA2A protein CTD PMID:26654777 NCBI chr10:75,152,711...75,170,626
Ensembl chr10:75,152,711...75,170,618
JBrowse link
G Adra1a adrenergic receptor, alpha 1a increases expression ISO Streptozocin results in increased expression of ADRA1A mRNA; Streptozocin results in increased expression of ADRA1A protein CTD PMID:19133277 NCBI chr14:66,872,705...67,009,549
Ensembl chr14:66,872,700...67,008,617
JBrowse link
G Adra1b adrenergic receptor, alpha 1b increases expression ISO Streptozocin results in increased expression of ADRA1B mRNA CTD PMID:19298542 NCBI chr11:43,665,432...43,792,076
Ensembl chr11:43,665,433...43,792,037
JBrowse link
G Adra1d adrenergic receptor, alpha 1d decreases expression ISO Streptozocin results in decreased expression of ADRA1D mRNA CTD PMID:19298542 NCBI chr 2:131,387,277...131,404,417
Ensembl chr 2:131,387,770...131,404,203
JBrowse link
G Adrb1 adrenergic receptor, beta 1 multiple interactions
decreases expression
ISO Metoprolol inhibits the reaction [Streptozocin results in decreased expression of ADRB1 protein] CTD PMID:18703049 NCBI chr19:56,710,549...56,713,582
Ensembl chr19:56,710,631...56,721,545
JBrowse link
G Adrb2 adrenergic receptor, beta 2 increases expression
multiple interactions
ISO Streptozocin results in increased expression of ADRB2 protein
Metoprolol promotes the reaction [Streptozocin results in increased expression of ADRB2 protein]
CTD PMID:18703049 NCBI chr18:62,310,784...62,313,052
Ensembl chr18:62,310,887...62,313,030
JBrowse link
G Adrb3 adrenergic receptor, beta 3 multiple interactions
increases expression
ISO Metoprolol promotes the reaction [Streptozocin results in increased expression of ADRB3 protein] CTD PMID:18703049 NCBI chr 8:27,715,804...27,720,833
Ensembl chr 8:27,715,804...27,740,644
JBrowse link
G Afmid arylformamidase increases expression ISO Streptozocin results in increased expression of AFMID mRNA CTD PMID:25905778 NCBI chr11:117,716,329...117,730,734
Ensembl chr11:117,716,750...117,730,734
JBrowse link
G Afp alpha fetoprotein multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of AFP mRNA CTD PMID:29127188 NCBI chr 5:90,638,573...90,656,766
Ensembl chr 5:90,638,596...90,656,766
JBrowse link
G Ager advanced glycosylation end product-specific receptor increases expression
multiple interactions
increases response to substance
ISO
EXP
Streptozocin results in increased expression of AGER mRNA; Streptozocin results in increased expression of AGER protein
[Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of AGER protein]; [Streptozocin co-treated with Dietary Fats] results in increased expression of AGER protein; Dimethyl Fumarate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of AGER protein]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of AGER protein]; Kangen-karyu inhibits the reaction [Streptozocin results in increased expression of AGER protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of AGER protein]; procyanidin B2 inhibits the reaction [Streptozocin results in increased expression of AGER protein]; Sodium Selenite inhibits the reaction [Streptozocin results in increased expression of AGER protein]; Zinc inhibits the reaction [Streptozocin results in increased expression of AGER mRNA]
manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Streptozocin results in increased expression of AGER mRNA]
AGER protein results in increased susceptibility to Streptozocin
CTD PMID:19397970 PMID:19833897 PMID:22476978 PMID:25199697 PMID:27109771 More... NCBI chr17:34,816,545...34,819,911
Ensembl chr17:34,816,836...34,819,910
JBrowse link
G Agrp agouti related neuropeptide multiple interactions
increases expression
ISO INS protein inhibits the reaction [Streptozocin results in increased expression of AGRP mRNA] CTD PMID:20219977 NCBI chr 8:106,293,327...106,306,477
Ensembl chr 8:106,293,330...106,364,025
JBrowse link
G Agt angiotensinogen multiple interactions
increases expression
decreases abundance
EXP
ISO
CEBPB protein affects the reaction [Streptozocin results in increased expression of AGT protein]; CEBPB protein inhibits the reaction [Streptozocin results in decreased abundance of AGT protein modified form]; IGF1 protein inhibits the reaction [Streptozocin results in increased expression of AGT protein]; Valsartan inhibits the reaction [Streptozocin results in decreased abundance of AGT protein modified form]; Valsartan promotes the reaction [Streptozocin results in increased expression of AGT protein]
ACE2 inhibits the reaction [Streptozocin results in increased expression of AGT protein modified form]; AGT protein modified form inhibits the reaction [Streptozocin results in decreased abundance of Cyclic GMP]; AGT protein modified form inhibits the reaction [Streptozocin results in increased expression of PDE5 mRNA]; benazepril inhibits the reaction [Streptozocin results in increased expression of AGT protein modified form]; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in increased expression of AGT protein]
Streptozocin results in increased expression of AGT mRNA; Streptozocin results in increased expression of AGT protein; Streptozocin results in increased expression of AGT protein modified form
CTD PMID:11375343 PMID:15643138 PMID:17724226 PMID:18487452 PMID:20547220 More... NCBI chr 8:125,283,326...125,296,445
Ensembl chr 8:125,283,273...125,296,445
JBrowse link
G Agtr1a angiotensin II receptor, type 1a multiple interactions
increases expression
EXP
ISO
2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of AGTR1A mRNA]; [Perindopril co-treated with AM6545] inhibits the reaction [Streptozocin results in increased expression of AGTR1A protein]; [Streptozocin co-treated with Niacinamide] results in increased expression of AGTR1A mRNA; AM6545 inhibits the reaction [Streptozocin results in increased expression of AGTR1A mRNA]; AM6545 inhibits the reaction [Streptozocin results in increased expression of AGTR1A protein]; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of AGTR1 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of AGTR1A mRNA]; Perindopril inhibits the reaction [Streptozocin results in increased expression of AGTR1A mRNA]; Perindopril inhibits the reaction [Streptozocin results in increased expression of AGTR1A protein]; Telmisartan inhibits the reaction [Streptozocin results in increased expression of AGTR1A protein]; Valsartan promotes the reaction [Streptozocin results in increased expression of AGTR1 protein]
Streptozocin results in increased expression of AGTR1 protein; Streptozocin results in increased expression of AGTR1A mRNA; Streptozocin results in increased expression of AGTR1A protein
[Streptozocin co-treated with Dietary Fats] results in increased expression of AGTR1A mRNA; esculetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of AGTR1A mRNA]
CTD PMID:17724226 PMID:18487452 PMID:21381899 PMID:28946194 PMID:29266779 More... NCBI chr13:30,520,339...30,566,850
Ensembl chr13:30,520,424...30,566,850
JBrowse link
G Agtr2 angiotensin II receptor, type 2 increases expression
multiple interactions
EXP
ISO
Streptozocin results in increased expression of AGTR2 mRNA; Streptozocin results in increased expression of AGTR2 protein
[Streptozocin co-treated with Dietary Fats] results in increased expression of AGTR2 mRNA; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in increased expression of AGTR2 mRNA]; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in increased expression of AGTR2 protein]; esculetin promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of AGTR2 mRNA]
CEBPB protein inhibits the reaction [Streptozocin results in increased expression of AGTR2 protein]; Valsartan inhibits the reaction [Streptozocin results in increased expression of AGTR2 protein]
CTD PMID:15587404 PMID:17724226 PMID:28946194 PMID:29266779 NCBI chr  X:21,350,863...21,355,072
Ensembl chr  X:21,350,783...21,355,403
JBrowse link
G Agxt2 alanine-glyoxylate aminotransferase 2 multiple interactions
decreases expression
ISO Trientine inhibits the reaction [Streptozocin results in decreased expression of AGXT2 protein] CTD PMID:19634143 NCBI chr15:10,358,602...10,410,244
Ensembl chr15:10,358,618...10,410,239
JBrowse link
G Ahcy S-adenosylhomocysteine hydrolase multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of AHCY mRNA; [Streptozocin co-treated with Dietary Fats] results in increased methylation of AHCY gene CTD PMID:29127188 NCBI chr 2:154,901,230...154,916,417
Ensembl chr 2:154,901,230...154,916,417
JBrowse link
G Ahr aryl-hydrocarbon receptor decreases expression EXP Streptozocin results in decreased expression of AHR mRNA CTD PMID:22531820 NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037
JBrowse link
G Aifm1 apoptosis-inducing factor, mitochondrion-associated 1 increases expression
multiple interactions
ISO
EXP
Streptozocin results in increased expression of AIFM1 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of AIFM1 protein]
[Streptozocin co-treated with NQO1 protein mutant form] results in increased expression of AIFM1 protein; FGF21 protein affects the reaction [Streptozocin results in increased expression of AIFM1]
CTD PMID:19634143 PMID:23458895 PMID:23499715 NCBI chr  X:47,563,821...47,602,440
Ensembl chr  X:47,563,821...47,602,440
JBrowse link
G Ajm1 apical junction component 1 multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of AJM1 mRNA CTD PMID:33484791 NCBI chr 2:25,465,428...25,471,760
Ensembl chr 2:25,465,428...25,471,769
JBrowse link
G Ak4 adenylate kinase 4 decreases expression
multiple interactions
ISO Streptozocin results in decreased expression of AK4 protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of AK4 protein]
CTD PMID:19634143 NCBI chr 4:101,273,675...101,324,968
Ensembl chr 4:101,276,474...101,324,192
JBrowse link
G Akr1a1 aldo-keto reductase family 1, member A1 increases expression
multiple interactions
ISO Streptozocin results in increased expression of AKR1A1 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of AKR1A1 protein]
CTD PMID:19634143 NCBI chr 4:116,493,707...116,508,871
Ensembl chr 4:116,493,707...116,508,877
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B multiple interactions ISO Streptozocin inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK1 protein]; Streptozocin inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK3 protein]; Streptozocin inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK8 protein]; Streptozocin inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK9 protein] CTD PMID:25541468 NCBI chr 6:34,280,865...34,294,424
Ensembl chr 6:34,279,369...34,294,413
JBrowse link
G Akr1c18 aldo-keto reductase family 1, member C18 multiple interactions ISO
EXP
[resveratrol co-treated with Streptozocin] results in decreased expression of AKR1C3 mRNA
[Streptozocin co-treated with Dietary Fats] results in increased expression of AKR1C18 mRNA
CTD PMID:25905778 PMID:29127188 NCBI chr13:4,182,614...4,200,645
Ensembl chr13:4,182,614...4,200,653
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 multiple interactions
decreases expression
decreases phosphorylation
increases phosphorylation
increases expression
decreases expression
ISO
EXP
[cobaltiprotoporphyrin co-treated with Streptozocin] results in increased phosphorylation of AKT1 protein; [Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of AKT1 protein; [Dietary Fats co-treated with Streptozocin] results in increased phosphorylation of AKT1 protein; [Resveratrol co-treated with Streptozocin] results in decreased phosphorylation of AKT1 protein; [Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in decreased phosphorylation of AKT1 protein; [Streptozocin co-treated with Niacinamide] results in decreased phosphorylation of AKT1 protein; asiatic acid inhibits the reaction [Streptozocin results in decreased expression of AKT1 protein]; cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased phosphorylation of AKT1 protein]; Curcumin inhibits the reaction [Streptozocin results in decreased phosphorylation of AKT1 protein]; dapagliflozin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of AKT1 protein]; eupafolin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased phosphorylation of AKT1 protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of AKT1 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in decreased phosphorylation of AKT1 protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of AKT1 mRNA]; morin inhibits the reaction [Streptozocin results in increased expression of AKT1 mRNA]; myrtenal inhibits the reaction [Streptozocin results in decreased expression of AKT1 protein]; nerolidol inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased phosphorylation of AKT1 protein]; Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of AKT1 mRNA]; piperlongumine inhibits the reaction [Streptozocin results in decreased expression of AKT1 protein]; Plant Extracts inhibits the reaction [[Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in decreased phosphorylation of AKT1 protein]; Propofol promotes the reaction [Streptozocin results in decreased phosphorylation of AKT1 protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased phosphorylation of AKT1 protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of AKT1 mRNA]; Rivastigmine inhibits the reaction [Streptozocin results in decreased expression of AKT1 mRNA]; Streptozocin results in decreased expression of and results in decreased phosphorylation of AKT1 protein; STUB1 inhibits the reaction [Streptozocin results in decreased expression of AKT1 protein]; tin mesoporphyrin inhibits the reaction [[cobaltiprotoporphyrin co-treated with Streptozocin] results in increased phosphorylation of AKT1 protein]; Tribulus extract inhibits the reaction [Streptozocin results in decreased phosphorylation of AKT1 protein]; Wortmannin inhibits the reaction [Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of AKT1 mRNA]]
Streptozocin results in decreased expression of AKT1 mRNA; Streptozocin results in decreased expression of AKT1 protein
[Dietary Fats co-treated with Streptozocin] results in decreased expression of AKT1 mRNA; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of AKT1 protein; [Streptozocin co-treated with CNR1 protein] affects the phosphorylation of AKT1 protein; [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased phosphorylation of AKT1 protein; [Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of AKT1 protein; Metformin inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of AKT1 protein]; Metformin inhibits the reaction [Streptozocin results in decreased phosphorylation of AKT1 protein]; perilla seed oil inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of AKT1 protein]; phillyrin inhibits the reaction [Streptozocin results in decreased phosphorylation of AKT1 protein]
streptozocin increases phosphorylation of Akt1 protein in heart
Streptozotocin decreases expression of Akt1 protein in the liver
Streptozocin decreases phosphorylation of Akt1 protein in the liver
CTD
RGD
PMID:16595661 PMID:19002579 PMID:22675305 PMID:24810525 PMID:25541178 More... RGD:156430337, RGD:14401598, RGD:408346751 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318
JBrowse link
G Akt2 thymoma viral proto-oncogene 2 multiple interactions ISO [Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of AKT2 protein; Butyric Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of AKT2 protein]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of AKT2 protein] CTD PMID:27270450 NCBI chr 7:27,290,977...27,340,251
Ensembl chr 7:27,290,977...27,340,251
JBrowse link
G Alad aminolevulinate, delta-, dehydratase multiple interactions EXP [Streptozocin results in increased abundance of Blood Glucose] which results in decreased expression of ALAD protein; alpha-Tocopherol inhibits the reaction [[Streptozocin results in increased abundance of Blood Glucose] which results in decreased expression of ALAD protein] CTD PMID:7728901 NCBI chr 4:62,422,762...62,438,300
Ensembl chr 4:62,427,406...62,438,155
JBrowse link
G Alas1 aminolevulinic acid synthase 1 decreases expression
multiple interactions
ISO Streptozocin results in decreased expression of ALAS1 mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in decreased expression of ALAS1 mRNA]
CTD PMID:16684804 NCBI chr 9:106,110,654...106,125,153
Ensembl chr 9:106,110,654...106,125,853
JBrowse link
G Alb albumin multiple interactions
increases secretion
decreases expression
increases expression
EXP
ISO
[Streptozocin co-treated with Dietary Fats co-treated with Carboxymethylcellulose Sodium] results in increased expression of ALB protein; AM6545 inhibits the reaction [Streptozocin results in increased expression of ALB protein]; naringenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Carboxymethylcellulose Sodium] results in increased expression of ALB protein]; Perindopril inhibits the reaction [Streptozocin results in increased expression of ALB protein]; TXN protein inhibits the reaction [Streptozocin results in increased secretion of ALB protein]
[bisphenol A co-treated with Streptozocin] results in decreased expression of ALB protein; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of ALB protein; [Streptozocin co-treated with Cadmium] results in increased expression of ALB protein; [Streptozocin co-treated with Cholesterol, Dietary] results in increased secretion of ALB protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of ALB protein; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of ALB protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of ALB protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of ALB protein]; Eugenol inhibits the reaction [Streptozocin results in decreased expression of ALB protein]; Gallic Acid inhibits the reaction [Streptozocin results in decreased expression of ALB protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Cholesterol, Dietary] results in increased secretion of ALB protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of ALB protein]; hesperetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of ALB protein]; LR-90 inhibits the reaction [Streptozocin results in increased expression of ALB protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of ALB protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of ALB protein]; Plant Extracts inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of ALB protein]; procyanidin B2 inhibits the reaction [Streptozocin results in increased expression of ALB protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of ALB protein]
CTD PMID:12845431 PMID:14871415 PMID:17360766 PMID:18204486 PMID:21450970 More... NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461
JBrowse link
G Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 increases expression ISO Streptozocin results in increased expression of ALDH1A1 mRNA CTD PMID:25905778 NCBI chr19:20,469,947...20,620,827
Ensembl chr19:20,470,079...20,620,829
JBrowse link
G Aldh1a3 aldehyde dehydrogenase family 1, subfamily A3 multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of ALDH1A3 mRNA CTD PMID:33484791 NCBI chr 7:66,040,640...66,077,225
Ensembl chr 7:66,040,638...66,077,265
JBrowse link
G Aldh2 aldehyde dehydrogenase 2, mitochondrial increases expression
decreases expression
multiple interactions
ISO Streptozocin results in increased expression of ALDH2 protein
Streptozocin results in decreased expression of ALDH2 mRNA; Streptozocin results in decreased expression of ALDH2 protein
Ethanol inhibits the reaction [Streptozocin results in decreased expression of ALDH2]
CTD PMID:21136691 PMID:23500772 NCBI chr 5:121,704,090...121,731,887
Ensembl chr 5:121,704,090...121,731,887
JBrowse link
G Aldob aldolase B, fructose-bisphosphate increases expression
multiple interactions
ISO Streptozocin results in increased expression of ALDOB protein
Trientine inhibits the reaction [Streptozocin results in increased expression of ALDOB protein]
CTD PMID:19634143 NCBI chr 4:49,535,993...49,549,546
Ensembl chr 4:49,535,995...49,549,546
JBrowse link
G Alkbh3 alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of ALKBH3 mRNA CTD PMID:20665664 NCBI chr 2:93,810,979...93,841,099
Ensembl chr 2:93,810,895...93,841,152
JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of ALOX5AP mRNA CTD PMID:29127188 NCBI chr 5:149,201,814...149,224,963
Ensembl chr 5:149,201,577...149,224,963
JBrowse link
G Alpk1 alpha-kinase 1 increases response to substance
multiple interactions
ISO ALPK1 protein results in increased susceptibility to Streptozocin
[ALPK1 protein results in increased susceptibility to Streptozocin] which results in decreased expression of PRKG2 mRNA; [ALPK1 protein results in increased susceptibility to Streptozocin] which results in increased expression of TGFB1 mRNA; [ALPK1 protein results in increased susceptibility to Streptozocin] which results in increased expression of TGFB1 protein; ALPK1 protein promotes the reaction [Streptozocin results in decreased secretion of INS1 protein]; ALPK1 protein promotes the reaction [Streptozocin results in increased abundance of Blood Glucose]
CTD PMID:27542954 NCBI chr 3:127,460,367...127,574,195
Ensembl chr 3:127,463,959...127,574,176
JBrowse link
G Ambn ameloblastin multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of AMBN mRNA CTD PMID:33484791 NCBI chr 5:88,603,850...88,616,390
Ensembl chr 5:88,603,850...88,616,390
JBrowse link
G Amigo1 adhesion molecule with Ig like domain 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of AMIGO1 protein CTD PMID:32495657 NCBI chr 3:108,093,605...108,099,602
Ensembl chr 3:108,093,651...108,099,602
JBrowse link
G Amy2-ps1 amylase 2, pseudogene 1 multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of AMY2-PS1 mRNA CTD PMID:33484791 NCBI chr 3:113,089,550...113,114,010
Ensembl chr 3:113,089,565...113,114,013
JBrowse link
G Angpt1 angiopoietin 1 increases expression
decreases expression
multiple interactions
ISO Streptozocin results in increased expression of ANGPT1 mRNA; Streptozocin results in increased expression of ANGPT1 protein
Streptozocin results in decreased expression of ANGPT1 mRNA
baicalin inhibits the reaction [Streptozocin results in decreased expression of ANGPT1 mRNA]
CTD PMID:15643138 PMID:19958114 PMID:34414639 NCBI chr15:42,288,063...42,540,373
Ensembl chr15:42,288,119...42,540,373
JBrowse link
G Angpt2 angiopoietin 2 multiple interactions
increases expression
ISO Enalapril inhibits the reaction [Streptozocin results in increased expression of ANGPT2 mRNA]; Simvastatin inhibits the reaction [Streptozocin results in increased expression of ANGPT2 protein]
Streptozocin results in increased expression of ANGPT2 mRNA; Streptozocin results in increased expression of ANGPT2 protein
CTD PMID:15643138 PMID:19958114 PMID:20821229 NCBI chr 8:18,740,279...18,791,578
Ensembl chr 8:18,740,279...18,791,578
JBrowse link
G Angptl4 angiopoietin-like 4 multiple interactions ISO [resveratrol co-treated with Streptozocin] results in decreased expression of ANGPTL4 mRNA CTD PMID:25905778 NCBI chr17:33,993,874...34,000,549
Ensembl chr17:33,992,724...34,000,804
JBrowse link
G Ankrd1 ankyrin repeat domain 1 increases expression
multiple interactions
ISO Streptozocin results in increased expression of ANKRD1 mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of ANKRD1 mRNA]
CTD PMID:16684804 NCBI chr19:36,089,365...36,097,244
Ensembl chr19:36,089,361...36,097,499
JBrowse link
G Ankrd2 ankyrin repeat domain 2 multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of ANKRD2 mRNA CTD PMID:33484791 NCBI chr19:42,024,358...42,033,550
Ensembl chr19:42,024,439...42,033,549
JBrowse link
G Anpep alanyl aminopeptidase, membrane decreases expression
multiple interactions
ISO Streptozocin results in decreased expression of ANPEP protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of ANPEP protein]
CTD PMID:19634143 NCBI chr 7:79,471,551...79,497,958
Ensembl chr 7:79,471,551...79,510,807
JBrowse link
G Anxa3 annexin A3 increases expression
multiple interactions
ISO Streptozocin results in increased expression of ANXA3 protein
[resveratrol co-treated with Streptozocin] results in increased expression of ANXA3 mRNA; Trientine inhibits the reaction [Streptozocin results in increased expression of ANXA3 protein]
CTD PMID:21136691 PMID:25905778 NCBI chr 5:96,941,257...96,993,825
Ensembl chr 5:96,941,198...96,993,825
JBrowse link
G Anxa5 annexin A5 decreases expression
increases expression
multiple interactions
ISO Streptozocin results in decreased expression of ANXA5 protein
Streptozocin results in increased expression of ANXA5 protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of ANXA5 protein]; Trientine inhibits the reaction [Streptozocin results in increased expression of ANXA5 protein]
CTD PMID:19634143 PMID:21136691 NCBI chr 3:36,503,072...36,530,036
Ensembl chr 3:36,503,072...36,530,043
JBrowse link
G Apex1 apurinic/apyrimidinic endonuclease 1 increases response to substance ISO APEX1 protein mutant form results in increased susceptibility to Streptozocin CTD PMID:19470598 NCBI chr14:51,162,406...51,164,645
Ensembl chr14:51,162,425...51,164,596
JBrowse link
G Apoa1 apolipoprotein A-I multiple interactions
increases expression
ISO Trientine inhibits the reaction [Streptozocin results in increased expression of APOA1 protein] CTD PMID:19634143 NCBI chr 9:46,139,928...46,141,767
Ensembl chr 9:46,139,878...46,141,764
JBrowse link
G Apoa4 apolipoprotein A-IV multiple interactions ISO [resveratrol co-treated with Streptozocin] results in decreased expression of APOA4 mRNA CTD PMID:25905778 NCBI chr 9:46,152,142...46,154,756
Ensembl chr 9:46,151,994...46,154,757
JBrowse link
G Apob apolipoprotein B multiple interactions ISO [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of APOB mRNA CTD PMID:35786680 NCBI chr12:8,027,629...8,066,839
Ensembl chr12:8,027,648...8,066,835
JBrowse link
G Apoe apolipoprotein E increases expression
multiple interactions
ISO
EXP
Streptozocin results in increased expression of APOE mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of APOE mRNA]
[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of ACACA mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of ACTA2 mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of ADGRE1 mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of CCL2 mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of CD36 mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of CD68 mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of COL3A1 mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of FASN mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of GPT protein; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of HSL mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of IGFBP1 mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of IGFBP1 protein; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of IL6 mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of LPL mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of LY6C1 mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of LY6G mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of PCK2 protein; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of PNPLA2 protein; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of PPARA mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of PPARA protein; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of PPARG mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of SREBF1 mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of TGFB1 mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of TNF mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the phosphorylation of GSK3B protein; [Streptozocin co-treated with APOE mutant form] results in increased abundance of Glucosamine; INS1 inhibits the reaction [[Streptozocin co-treated with APOE mutant form] results in increased abundance of Glucosamine]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of ACACA mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of ACTA2 mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of ADGRE1 mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of CCL2 mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of CD36 mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of CD68 mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of COL3A1 mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of CPT1A protein]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of FASN mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of GPT protein]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of IGFBP1 mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of IGFBP1 protein]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of IL6 mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of LPL mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of LY6C1 mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of LY6G mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of PCK2 protein]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of PNPLA2 protein]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of PPARA mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of PPARA protein]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of SREBF1 mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of TGFB1 mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of TNF mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the phosphorylation of GSK3B protein]
CTD PMID:16380481 PMID:16684804 PMID:39047806 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113
JBrowse link
G App amyloid beta precursor protein multiple interactions
increases expression
ISO
EXP
Memantine inhibits the reaction [Streptozocin results in increased expression of APP protein modified form]
Streptozocin results in increased expression of APP mRNA; Streptozocin results in increased expression of APP protein; Streptozocin results in increased expression of APP protein modified form
5-Methoxypsoralen inhibits the reaction [Streptozocin results in increased expression of APP protein modified form]; Alendronate inhibits the reaction [Streptozocin results in increased expression of APP protein]; Donepezil inhibits the reaction [Streptozocin results in increased expression of APP protein]; Tadalafil inhibits the reaction [Streptozocin results in increased expression of APP protein modified form]
CTD PMID:21069392 PMID:21290839 PMID:30481507 PMID:34428446 NCBI chr16:84,751,236...84,972,187
Ensembl chr16:84,746,573...84,970,654
JBrowse link
G Aqp1 aquaporin 1 multiple interactions
decreases expression
ISO Trientine inhibits the reaction [Streptozocin results in decreased expression of AQP1 protein] CTD PMID:19634143 NCBI chr 6:55,313,284...55,325,540
Ensembl chr 6:55,313,417...55,325,540
JBrowse link
G Aqp7 aquaporin 7 increases expression
multiple interactions
ISO Streptozocin results in increased expression of AQP7 mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of AQP7 mRNA]
CTD PMID:16684804 NCBI chr 4:41,033,074...41,048,237
Ensembl chr 4:41,033,074...41,048,139
JBrowse link
G Aqp9 aquaporin 9 increases expression ISO Streptozocin results in increased expression of AQP9 protein CTD PMID:22114114 NCBI chr 9:71,017,941...71,075,170
Ensembl chr 9:71,017,941...71,075,964
JBrowse link
G Arg1 arginase, liver multiple interactions
increases expression
decreases expression
increases activity
EXP
ISO
[NTN1 protein co-treated with Streptozocin] results in increased expression of ARG1 protein; AM6545 inhibits the reaction [Streptozocin results in decreased expression of ARG1 mRNA]; ARG1 gene mutant form inhibits the reaction [Streptozocin results in increased expression of GLB1 protein]; Perindopril inhibits the reaction [AM6545 inhibits the reaction [Streptozocin results in decreased expression of ARG1 mRNA]]
Streptozocin results in increased expression of ARG1 protein
Streptozocin results in increased activity of ARG1 protein
CTD PMID:29059224 PMID:29673160 PMID:30184259 PMID:34039237 NCBI chr10:24,791,105...24,803,368
Ensembl chr10:24,791,119...24,803,382
JBrowse link
G Arhgap9 Rho GTPase activating protein 9 multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of ARHGAP9 mRNA CTD PMID:25905778 NCBI chr10:127,157,829...127,165,816
Ensembl chr10:127,157,833...127,165,812
JBrowse link
G Asns asparagine synthetase multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of ASNS mRNA CTD PMID:25905778 NCBI chr 6:7,675,169...7,693,209
Ensembl chr 6:7,675,169...7,693,254
JBrowse link
G Atf2 activating transcription factor 2 increases expression
multiple interactions
ISO Streptozocin results in increased expression of ATF2 protein
resveratrol inhibits the reaction [Streptozocin results in increased expression of ATF2 protein]
CTD PMID:26499206 NCBI chr 2:73,646,853...73,723,094
Ensembl chr 2:73,646,853...73,722,983
JBrowse link
G Atf3 activating transcription factor 3 multiple interactions EXP [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of ATF3 mRNA]; [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of ATF3 protein]; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of ATF3 mRNA; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of ATF3 protein CTD PMID:38282657 NCBI chr 1:190,902,493...190,915,530
Ensembl chr 1:190,902,493...190,950,236
JBrowse link
G Atf4 activating transcription factor 4 multiple interactions
increases expression
increases phosphorylation
EXP
ISO
[Dietary Fats co-treated with Streptozocin] results in increased expression of ATF4 mRNA; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of ATF4 mRNA]; sulforaphane inhibits the reaction [Streptozocin results in increased expression of ATF4 protein]
Streptozocin results in increased phosphorylation of ATF4 protein
4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased phosphorylation of ATF4 protein]
CTD PMID:24967692 PMID:30980806 PMID:33812996 NCBI chr15:80,139,385...80,141,746
Ensembl chr15:80,139,385...80,141,742
JBrowse link
G Atf5 activating transcription factor 5 decreases expression ISO Streptozocin results in decreased expression of ATF5 mRNA CTD PMID:25905778 NCBI chr 7:44,461,680...44,466,082
Ensembl chr 7:44,461,680...44,466,082
JBrowse link
G Atf6 activating transcription factor 6 multiple interactions
increases cleavage
increases expression
ISO
EXP
4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased cleavage of ATF6 protein]; [Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of ATF6 protein; Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of ATF6 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of ATF6 protein]
[Dietary Fats co-treated with Streptozocin] results in increased expression of ATF6 mRNA; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of ATF6 mRNA]
streptozocin increases expression of Atf6 protein in heart
CTD
RGD
PMID:30980806 PMID:33812996 PMID:34801538 PMID:36044268 RGD:156430337 NCBI chr 1:170,532,026...170,696,414
Ensembl chr 1:170,532,243...170,695,340
JBrowse link
G Atg12 autophagy related 12 increases expression EXP Streptozocin results in increased expression of ATG12 mRNA CTD PMID:24889822 NCBI chr18:46,865,484...46,874,683
Ensembl chr18:46,863,211...46,874,647
JBrowse link
G Atg5 autophagy related 5 increases expression
multiple interactions
EXP
ISO
Streptozocin results in increased expression of ATG5 mRNA
[[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in decreased expression of ATG5 mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of ATG5 mRNA
Streptozocin results in increased expression of ATG5 protein
CTD PMID:24889822 PMID:35786680 PMID:38706688 NCBI chr10:44,144,325...44,240,295
Ensembl chr10:44,144,354...44,240,287
JBrowse link
G Atox1 antioxidant 1 copper chaperone decreases expression ISO Streptozocin results in decreased expression of ATOX1 protein CTD PMID:24927960 NCBI chr11:55,337,463...55,352,034
Ensembl chr11:55,337,467...55,352,065
JBrowse link
G Atp2a2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 decreases activity
multiple interactions
decreases expression
ISO
EXP
Streptozocin results in decreased activity of ATP2A2 protein
[bisphenol A co-treated with Streptozocin] results in decreased expression of ATP2A2 mRNA; [Ethinyl Estradiol co-treated with Streptozocin] results in decreased expression of ATP2A2 mRNA; [octylphenol co-treated with Streptozocin] results in decreased expression of ATP2A2 mRNA
Streptozocin results in decreased expression of ATP2A2 mRNA
Triterpenes inhibits the reaction [Streptozocin results in decreased expression of ATP2A2 mRNA]; Triterpenes inhibits the reaction [Streptozocin results in decreased expression of ATP2A2 protein]
Streptozocin results in decreased expression of ATP2A2 mRNA; Streptozocin results in decreased expression of ATP2A2 protein
CTD PMID:16685413 PMID:19000375 PMID:29935216 NCBI chr 5:122,591,576...122,640,288
Ensembl chr 5:122,591,576...122,640,288
JBrowse link
G Atp2a3 ATPase, Ca++ transporting, ubiquitous multiple interactions EXP [Streptozocin co-treated with bisphenol A] results in decreased expression of ATP2A3 mRNA; [Streptozocin co-treated with octylphenol] results in decreased expression of ATP2A3 mRNA CTD PMID:29935216 NCBI chr11:72,851,995...72,883,869
Ensembl chr11:72,851,995...72,883,870
JBrowse link
G Atp2b1 ATPase, Ca++ transporting, plasma membrane 1 multiple interactions
increases expression
EXP [Streptozocin co-treated with bisphenol A] results in increased expression of ATP2B1 mRNA; [Streptozocin co-treated with octylphenol] results in increased expression of ATP2B1 mRNA
Streptozocin results in increased expression of ATP2B1 mRNA
CTD PMID:29935216 NCBI chr10:98,750,243...98,862,005
Ensembl chr10:98,750,268...98,862,005
JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha increases expression
multiple interactions
ISO Streptozocin results in increased expression of ATP5F1A protein
Trientine inhibits the reaction [Streptozocin results in increased expression of ATP5F1A protein]
CTD PMID:21136691 NCBI chr18:77,861,468...77,870,569
Ensembl chr18:77,861,429...77,870,569
JBrowse link
G Atp5f1b ATP synthase F1 subunit beta increases expression
multiple interactions
ISO Streptozocin results in increased expression of ATP5F1B protein
Trientine inhibits the reaction [Streptozocin results in increased expression of ATP5F1B protein]
CTD PMID:21136691 NCBI chr10:127,919,176...127,926,257
Ensembl chr10:127,919,142...127,926,260
JBrowse link
G Atp5mf ATP synthase membrane subunit f increases expression
multiple interactions
affects expression
ISO
EXP
Streptozocin results in increased expression of ATP5MF protein
Trientine inhibits the reaction [Streptozocin results in increased expression of ATP5MF protein]
Streptozocin affects the expression of ATP5MF mRNA
CTD PMID:18583417 PMID:19634143 NCBI chr 5:145,120,514...145,128,351
Ensembl chr 5:145,120,508...145,128,872
JBrowse link
G Atp5po ATP synthase peripheral stalk subunit OSCP increases expression
multiple interactions
ISO Streptozocin results in increased expression of ATP5PO protein
Trientine inhibits the reaction [Streptozocin results in increased expression of ATP5PO protein]
CTD PMID:19634143 NCBI chr16:91,722,111...91,728,518
Ensembl chr16:91,722,102...91,728,575
Ensembl chr16:91,722,102...91,728,575
JBrowse link
G Atp6ap2 ATPase, H+ transporting, lysosomal accessory protein 2 multiple interactions
increases expression
ISO (3,4-dihydroxyphenylamino)-2-imidazoline inhibits the reaction [Streptozocin results in increased expression of ATP6AP2 mRNA]; (3,4-dihydroxyphenylamino)-2-imidazoline inhibits the reaction [Streptozocin results in increased expression of ATP6AP2 protein]; Valsartan inhibits the reaction [Streptozocin results in increased expression of ATP6AP2 mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of ATP6AP2 protein]
Streptozocin results in increased expression of ATP6AP2 mRNA; Streptozocin results in increased expression of ATP6AP2 protein
CTD PMID:18192338 NCBI chr  X:12,453,998...12,483,290
Ensembl chr  X:12,454,040...12,483,288
JBrowse link
G Atp7a ATPase, copper transporting, alpha polypeptide multiple interactions
decreases expression
EXP ATP7A gene mutant form promotes the reaction [Streptozocin results in increased chemical synthesis of Superoxides]; ATP7A protein inhibits the reaction [Streptozocin results in increased chemical synthesis of Superoxides]; INS protein inhibits the reaction [Streptozocin results in decreased expression of ATP7A protein] CTD PMID:23884884 NCBI chr  X:105,070,830...105,171,766
Ensembl chr  X:105,070,882...105,168,532
JBrowse link
G Atp7b ATPase, copper transporting, beta polypeptide decreases expression ISO Streptozocin results in decreased expression of ATP7B protein CTD PMID:24927960 NCBI chr 8:22,482,799...22,550,347
Ensembl chr 8:22,482,801...22,550,321
JBrowse link
G Avp arginine vasopressin multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in increased expression of AVP mRNA; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in increased expression of AVP mRNA] CTD PMID:32303808 NCBI chr 2:130,422,540...130,424,508
Ensembl chr 2:130,422,540...130,424,474
JBrowse link
G Axl AXL receptor tyrosine kinase increases expression ISO Streptozocin results in increased expression of AXL protein CTD PMID:12644472 NCBI chr 7:25,455,925...25,488,502
Ensembl chr 7:25,456,698...25,488,130
JBrowse link
G B2m beta-2 microglobulin multiple interactions
increases expression
ISO
EXP
diphenyldiselenide inhibits the reaction [Streptozocin results in increased activity of B2M protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of B2M protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of B2M protein]
Metformin inhibits the reaction [Streptozocin results in increased expression of B2M protein]; phillyrin inhibits the reaction [Streptozocin results in increased expression of B2M protein]
CTD PMID:33639173 PMID:34649470 NCBI chr 2:121,978,168...121,983,563
Ensembl chr 2:121,978,167...121,983,564
JBrowse link
G B3galnt1 UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 1 multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of B3GALNT1 mRNA CTD PMID:25905778 NCBI chr 3:69,481,252...69,506,305
Ensembl chr 3:69,481,491...69,506,293
JBrowse link
G Baat bile acid-Coenzyme A: amino acid N-acyltransferase multiple interactions EXP [Dietary Fats co-treated with Streptozocin] results in decreased expression of BAAT mRNA CTD PMID:29382564 NCBI chr 4:49,489,416...49,507,915
Ensembl chr 4:49,489,422...49,506,557
JBrowse link
G Bace1 beta-site APP cleaving enzyme 1 multiple interactions
increases expression
EXP Alendronate inhibits the reaction [Streptozocin results in increased expression of BACE1 protein]; Donepezil inhibits the reaction [Streptozocin results in increased expression of BACE1 protein] CTD PMID:30481507 NCBI chr 9:45,749,878...45,775,694
Ensembl chr 9:45,749,878...45,775,697
JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions
decreases expression
increases expression
ISO Anthocyanins inhibits the reaction [Streptozocin results in decreased expression of BAD protein modified form]; Anthocyanins inhibits the reaction [Streptozocin results in increased expression of BAD protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased expression of BAD protein]; Streptozocin results in increased phosphorylation of and results in decreased activity of BAD protein
Streptozocin results in decreased expression of BAD protein; Streptozocin results in decreased expression of BAD protein modified form
CTD PMID:15976052 PMID:19682444 PMID:28856781 NCBI chr19:6,919,229...6,929,273
Ensembl chr19:6,919,229...6,929,267
JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions
increases expression
ISO Anthocyanins inhibits the reaction [Streptozocin results in increased expression of BAK1 protein] CTD PMID:28856781 NCBI chr17:27,238,786...27,247,601
Ensembl chr17:27,238,784...27,247,983
JBrowse link
G Bax BCL2-associated X protein multiple interactions
increases expression
affects expression
EXP
ISO
[Streptozocin co-treated with Dietary Fats] results in increased expression of BAX mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of BAX protein; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of BAX protein]; IGF1 protein inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of BAX protein]; montelukast inhibits the reaction [Streptozocin results in increased expression of BAX protein]; phillyrin inhibits the reaction [Streptozocin results in increased expression of BAX protein]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of BAX mRNA]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of BAX protein]; sulforaphane inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Valsartan inhibits the reaction [Streptozocin results in increased expression of BAX protein]
Streptozocin results in increased expression of BAX; Streptozocin results in increased expression of BAX mRNA; Streptozocin results in increased expression of BAX protein
2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BAX protein]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Streptozocin results in increased expression of BAX protein]; 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of BAX protein]; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of BAX protein; [Streptozocin co-treated with Isoproterenol] affects the expression of BAX protein; Angiotensin-Converting Enzyme Inhibitors inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Ascorbic Acid inhibits the reaction [Streptozocin results in increased expression of BAX protein]; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of BAX protein]; bisphenol A diglycidyl ether inhibits the reaction [Calcitriol inhibits the reaction [Streptozocin results in increased expression of BAX protein]]; Calcitriol inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Curcumin inhibits the reaction [Streptozocin affects the expression of BAX protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; Diazoxide inhibits the reaction [Streptozocin results in increased expression of BAX protein]; fasudil inhibits the reaction [Streptozocin results in increased expression of BAX protein]; ferulic acid inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of BAX protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Hesperidin inhibits the reaction [2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BAX protein]]; Hesperidin inhibits the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BAX protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; Metformin inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; morin inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; Organoselenium Compounds inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Pentoxifylline inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Phosphocreatine inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Phycocyanin inhibits the reaction [Streptozocin results in increased expression of BAX protein]; piperlongumine inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of BAX]; Rivastigmine inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Sildenafil Citrate inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; Sildenafil Citrate promotes the reaction [Tadalafil inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]]; Streptozocin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of BAX protein]; Tadalafil inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; Tadalafil promotes the reaction [Sildenafil Citrate inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]]; Testosterone inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; Testosterone promotes the reaction [Sildenafil Citrate inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]]; Testosterone promotes the reaction [Sildenafil Citrate promotes the reaction [Tadalafil inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]]]; Testosterone promotes the reaction [Tadalafil inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]]; Testosterone promotes the reaction [Tadalafil promotes the reaction [Sildenafil Citrate inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]]]; Wortmannin inhibits the reaction [Phycocyanin inhibits the reaction [Streptozocin results in increased expression of BAX protein]]; Zinc inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; Zinc inhibits the reaction [Streptozocin results in increased expression of BAX protein]
CTD PMID:11375343 PMID:18758938 PMID:19931367 PMID:20574430 PMID:20650802 More... NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Baz1b bromodomain adjacent to zinc finger domain, 1B affects expression EXP Streptozocin affects the expression of BAZ1B mRNA CTD PMID:26073000 NCBI chr 5:135,214,094...135,274,985
Ensembl chr 5:135,216,118...135,274,983
JBrowse link
G Bbox1 gamma-butyrobetaine hydroxylase 1 multiple interactions ISO [resveratrol co-treated with Streptozocin] results in decreased expression of BBOX1 mRNA CTD PMID:25905778 NCBI chr 2:110,094,401...110,145,158
Ensembl chr 2:110,093,042...110,144,905
JBrowse link
G Bche butyrylcholinesterase multiple interactions
increases activity
EXP Acetylcysteine inhibits the reaction [Streptozocin results in increased activity of BCHE protein] CTD PMID:27087133 PMID:30481507 NCBI chr 3:73,543,138...73,615,767
Ensembl chr 3:73,543,141...73,615,748
JBrowse link
G Bckdha branched chain ketoacid dehydrogenase E1, alpha polypeptide affects expression EXP Streptozocin affects the expression of BCKDHA mRNA CTD PMID:18583417 NCBI chr 7:25,329,371...25,358,178
Ensembl chr 7:25,329,371...25,358,406
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 increases expression
decreases expression
multiple interactions
affects expression
ISO
EXP
Streptozocin results in increased expression of BCL2 protein
Streptozocin results in decreased expression of BCL2 mRNA; Streptozocin results in decreased expression of BCL2 protein
[Diethylhexyl Phthalate co-treated with Streptozocin co-treated with Dietary Fats] results in decreased expression of BCL2 protein; [Streptozocin co-treated with arachidonyl-2-chloroethylamide] results in increased expression of BCL2 protein; [Streptozocin co-treated with bisphenol A] results in increased expression of BCL2 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of BCL2 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of BCL2 protein; [Streptozocin co-treated with Ethinyl Estradiol] results in increased expression of BCL2 mRNA; [Streptozocin co-treated with octylphenol] results in increased expression of BCL2 mRNA; AM 251 inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; bisphenol A promotes the reaction [Streptozocin results in decreased expression of BCL2 protein]; CEBPB protein inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; CNR1 protein promotes the reaction [Streptozocin results in decreased expression of BCL2 protein]; Ethinyl Estradiol promotes the reaction [Streptozocin results in decreased expression of BCL2 protein]; Metformin inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; montelukast inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; octylphenol promotes the reaction [Streptozocin results in decreased expression of BCL2 protein]; phillyrin inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of BCL2 mRNA]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of BCL2 protein]; Streptozocin inhibits the reaction [Cisplatin results in increased expression of BCL2 protein]; Valsartan inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]
2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BCL2 protein]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of BCL2 protein; [Rolipram co-treated with Pentoxifylline] inhibits the reaction [Streptozocin results in increased expression of BCL2 protein]; [Streptozocin co-treated with Arsenic] results in decreased expression of BCL2 mRNA; [Streptozocin co-treated with Cadmium] results in decreased expression of BCL2 mRNA; [Streptozocin co-treated with Isoproterenol] affects the expression of BCL2 protein; [Streptozocin co-treated with Lead co-treated with Manganese co-treated with Cadmium co-treated with Arsenic] results in decreased expression of BCL2 mRNA; [Streptozocin co-treated with Lead] results in decreased expression of BCL2 mRNA; [Streptozocin co-treated with Manganese] results in decreased expression of BCL2 mRNA; Angiotensin-Converting Enzyme Inhibitors inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Anthocyanins inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased expression of BCL2 protein]; Ascorbic Acid inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of BCL2 protein]; bisphenol A diglycidyl ether inhibits the reaction [Calcitriol inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]]; Calcitriol inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Curcumin inhibits the reaction [Streptozocin affects the expression of BCL2 protein]; dapagliflozin inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]; Diazoxide inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; fasudil inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of BCL2 protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Hesperidin inhibits the reaction [2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BCL2 protein]]; Hesperidin inhibits the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BCL2 protein]; IGF2R protein modified form promotes the reaction [Streptozocin results in decreased expression of BCL2 protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of BCL2 mRNA]; morin inhibits the reaction [Streptozocin results in increased expression of BCL2 mRNA]; Organoselenium Compounds inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Pentoxifylline inhibits the reaction [Streptozocin results in increased expression of BCL2 protein]; Phosphocreatine inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; piperlongumine inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Propofol inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Rivastigmine inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Sildenafil Citrate inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]; Sildenafil Citrate promotes the reaction [Tadalafil inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]]; Streptozocin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased expression of BCL2 protein]; Streptozocin promotes the reaction [IGF2R protein modified form results in decreased expression of BCL2 protein modified form]; Tadalafil inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]; Tadalafil promotes the reaction [Sildenafil Citrate inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]]; Testosterone inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]; Testosterone promotes the reaction [Sildenafil Citrate inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]]; Testosterone promotes the reaction [Sildenafil Citrate promotes the reaction [Tadalafil inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]]]; Testosterone promotes the reaction [Tadalafil inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]]; Testosterone promotes the reaction [Tadalafil promotes the reaction [Sildenafil Citrate inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]]]; Zinc inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]; Zinc inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]
CTD PMID:15056984 PMID:15587404 PMID:15976052 PMID:16909474 PMID:18758938 More... NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Bcl2a1b B cell leukemia/lymphoma 2 related protein A1b multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of BCL2A1 mRNA CTD PMID:25905778 NCBI chr 9:89,081,326...89,089,891
Ensembl chr 9:89,081,262...89,089,880
JBrowse link
G Bcl2l1 BCL2-like 1 increases expression
multiple interactions
decreases expression
ISO
EXP
Streptozocin results in increased expression of BCL2L1 protein
Anthocyanins inhibits the reaction [Streptozocin results in decreased expression of BCL2L1 protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased expression of BCL2L1 protein]; Ascorbic Acid inhibits the reaction [Streptozocin results in decreased expression of BCL2L1 protein]; cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of BCL2L1 protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of BCL2L1 mRNA]; morin inhibits the reaction [Streptozocin results in increased expression of BCL2L1 mRNA]; tin mesoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of BCL2L1 protein]]
Streptozocin results in decreased expression of BCL2L1 mRNA; Streptozocin results in decreased expression of BCL2L1 protein
CTD PMID:15976052 PMID:16595661 PMID:18758938 PMID:19682444 PMID:24781736 More... NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648
JBrowse link
G Bcl2l11 BCL2 like 11 increases expression
multiple interactions
EXP Streptozocin results in increased expression of BCL2L11 mRNA
Chlorpyrifos promotes the reaction [Streptozocin results in increased expression of BCL2L11 mRNA]
CTD PMID:33524429 NCBI chr 2:127,967,958...128,004,467
Ensembl chr 2:127,967,958...128,004,467
JBrowse link
G Bcl3 B cell leukemia/lymphoma 3 multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of BCL3 mRNA CTD PMID:25905778 NCBI chr 7:19,542,387...19,556,691
Ensembl chr 7:19,542,387...19,556,695
JBrowse link
G Bdh1 3-hydroxybutyrate dehydrogenase, type 1 multiple interactions ISO [resveratrol co-treated with Streptozocin] results in decreased expression of BDH1 mRNA CTD PMID:25905778 NCBI chr16:31,241,115...31,277,719
Ensembl chr16:31,241,098...31,277,719
JBrowse link
G Bdkrb1 bradykinin receptor, beta 1 increases expression
multiple interactions
EXP
ISO
Streptozocin results in increased expression of BDKRB1 mRNA
[HOE 140, desArg(10)- binds to and results in decreased activity of BDKRB1 protein] which results in decreased susceptibility to Streptozocin
CTD PMID:17989505 PMID:19516248 NCBI chr12:105,570,350...105,571,770
Ensembl chr12:105,569,344...105,571,687
JBrowse link
G Bdkrb2 bradykinin receptor, beta 2 increases expression
multiple interactions
EXP
ISO
Streptozocin results in increased expression of BDKRB2 mRNA
[icatibant binds to and results in decreased activity of BDKRB2 protein] which results in decreased susceptibility to Streptozocin
CTD PMID:17989505 PMID:19516248 NCBI chr12:105,529,431...105,561,503
Ensembl chr12:105,529,485...105,561,496
JBrowse link
G Bdnf brain derived neurotrophic factor multiple interactions
decreases expression
ISO
EXP
Metformin inhibits the reaction [Streptozocin results in increased expression of BDNF mRNA]; morin inhibits the reaction [Streptozocin results in increased expression of BDNF mRNA]; Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of BDNF protein]; Rivastigmine inhibits the reaction [Streptozocin results in decreased expression of BDNF protein]; Vitamin B 12 inhibits the reaction [Streptozocin results in decreased expression of BDNF protein]; Wortmannin inhibits the reaction [Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of BDNF protein]]
Streptozocin results in decreased expression of BDNF mRNA; Streptozocin results in decreased expression of BDNF protein
5-Methoxypsoralen inhibits the reaction [Streptozocin results in decreased expression of BDNF protein]; Tadalafil inhibits the reaction [Streptozocin results in decreased expression of BDNF protein]
CTD PMID:32805344 PMID:34428446 PMID:35414346 PMID:38049026 NCBI chr 2:109,505,045...109,557,388
Ensembl chr 2:109,505,045...109,557,352
JBrowse link
G Becn1 beclin 1, autophagy related increases expression
decreases expression
multiple interactions
EXP
ISO
Streptozocin results in increased expression of BECN1 mRNA; Streptozocin results in increased expression of BECN1 protein
Streptozocin results in decreased expression of BECN1 protein; Streptozocin results in decreased expression of BECN1 protein modified form
5-Methoxypsoralen inhibits the reaction [Streptozocin results in decreased expression of BECN1 protein modified form]; HU 308 inhibits the reaction [Streptozocin results in decreased expression of BECN1 protein]; Tadalafil inhibits the reaction [Streptozocin results in decreased expression of BECN1 protein modified form]
[[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of BECN1 mRNA; dapagliflozin affects the reaction [Streptozocin results in decreased expression of BECN1 mRNA]
CTD PMID:24889822 PMID:30459625 PMID:34428446 PMID:35786680 PMID:37352119 NCBI chr11:101,179,084...101,193,112
Ensembl chr11:101,176,778...101,193,112
JBrowse link
G Bglap bone gamma carboxyglutamate protein decreases expression
multiple interactions
ISO
EXP
Streptozocin results in decreased expression of BGLAP mRNA; Streptozocin results in decreased expression of BGLAP protein
[Dietary Fats co-treated with Streptozocin] results in decreased expression of BGLAP protein modified form; Warfarin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of BGLAP protein modified form]
[Streptozocin co-treated with Dietary Fats] results in decreased expression of BGLAP protein; Calcitriol inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of BGLAP protein]
CTD PMID:25617479 PMID:27488359 PMID:33450223 NCBI chr 3:88,290,802...88,291,773
Ensembl chr 3:88,290,808...88,291,771
JBrowse link
G Bhmt betaine-homocysteine methyltransferase increases activity
increases expression
multiple interactions
ISO
EXP
Streptozocin results in increased activity of BHMT protein
Streptozocin results in increased expression of BHMT mRNA
[Streptozocin co-treated with Dietary Fats] affects the expression of BHMT mRNA
CTD PMID:16835399 PMID:29127188 NCBI chr13:93,753,399...93,774,266
Ensembl chr13:93,753,183...93,774,469
JBrowse link
G Bmal1 basic helix-loop-helix ARNT like 1 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of BMAL1 mRNA CTD PMID:29127188 NCBI chr 7:112,777,820...112,913,333
Ensembl chr 7:112,806,672...112,913,333
JBrowse link
G Bmp6 bone morphogenetic protein 6 decreases expression
multiple interactions
ISO Streptozocin results in decreased expression of BMP6 mRNA
esculetin inhibits the reaction [Streptozocin results in decreased expression of BMP6 mRNA]
CTD PMID:21450970 NCBI chr13:38,529,098...38,684,283
Ensembl chr13:38,529,083...38,684,278
JBrowse link
G Bmp7 bone morphogenetic protein 7 increases expression
affects expression
ISO Streptozocin results in increased expression of BMP7 protein
Streptozocin affects the expression of BMP7 mRNA
CTD PMID:17437042 NCBI chr 2:172,709,805...172,782,114
Ensembl chr 2:172,709,805...172,782,114
JBrowse link
G C1qa complement component 1, q subcomponent, alpha polypeptide multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of C1QA mRNA CTD PMID:25905778 NCBI chr 4:136,623,227...136,626,155
Ensembl chr 4:136,623,228...136,626,114
JBrowse link
G C1qb complement component 1, q subcomponent, beta polypeptide increases expression
multiple interactions
ISO Streptozocin results in increased expression of C1QB mRNA
[resveratrol co-treated with Streptozocin] results in increased expression of C1QB mRNA; vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of C1QB mRNA]
CTD PMID:16684804 PMID:25905778 NCBI chr 4:136,607,437...136,613,511
Ensembl chr 4:136,607,440...136,613,498
JBrowse link
G C1qc complement component 1, q subcomponent, C chain multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of C1QC mRNA CTD PMID:25905778 NCBI chr 4:136,617,115...136,620,225
Ensembl chr 4:136,617,115...136,620,376
JBrowse link
G C4b complement C4B (Chido blood group) increases expression
multiple interactions
ISO Streptozocin results in increased expression of C4B mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of C4B mRNA]
CTD PMID:16684804 NCBI chr17:34,947,249...34,962,876
Ensembl chr17:34,947,354...34,962,856
JBrowse link
G Cacna1b calcium channel, voltage-dependent, N type, alpha 1B subunit multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of CACNA1B mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CACNA1B mRNA] CTD PMID:33484791 NCBI chr 2:24,493,872...24,653,210
Ensembl chr 2:24,493,899...24,653,164
JBrowse link
G Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit multiple interactions
increases expression
EXP [bisphenol A co-treated with Streptozocin] results in decreased expression of CACNA1C mRNA; [octylphenol co-treated with Streptozocin] results in decreased expression of CACNA1C mRNA
Streptozocin results in increased expression of CACNA1C mRNA
CTD PMID:29935216 NCBI chr 6:118,564,201...119,174,345
Ensembl chr 6:118,564,201...119,173,851
JBrowse link
G Cacna1s calcium channel, voltage-dependent, L type, alpha 1S subunit multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of CACNA1S mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CACNA1S mRNA] CTD PMID:33484791 NCBI chr 1:135,980,549...136,047,268
Ensembl chr 1:135,980,488...136,047,560
JBrowse link
G Calca calcitonin/calcitonin-related polypeptide, alpha multiple interactions
decreases expression
ISO Botulinum Toxins, Type A inhibits the reaction [Streptozocin results in decreased expression of CALCA protein]; capsazepine inhibits the reaction [Streptozocin results in decreased expression of CALCA protein]; RN 1734 inhibits the reaction [Streptozocin results in decreased expression of CALCA protein]; U 0126 inhibits the reaction [Streptozocin results in decreased expression of CALCA protein] CTD PMID:30583000 NCBI chr 7:114,225,223...114,236,145
Ensembl chr 7:114,230,713...114,235,592
JBrowse link
G Calm1 calmodulin 1 multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in increased expression of CALM1 protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in increased expression of CALM1 protein] CTD PMID:32303808 NCBI chr12:100,165,694...100,176,083
Ensembl chr12:100,165,694...100,176,073
JBrowse link
G Calm3 calmodulin 3 decreases expression
multiple interactions
ISO Streptozocin results in decreased expression of CALM3 protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of CALM3 protein]
CTD PMID:19634143 NCBI chr 7:16,649,304...16,657,957
Ensembl chr 7:16,649,304...16,658,039
JBrowse link
G Calr calreticulin decreases expression
multiple interactions
ISO Streptozocin results in decreased expression of CALR protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of CALR protein]
CTD PMID:19634143 NCBI chr 8:85,568,717...85,573,560
Ensembl chr 8:85,568,479...85,573,563
JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha multiple interactions
decreases expression
EXP
ISO
myristoylated autocamtide-2-related inhibitory peptide inhibits the reaction [Streptozocin results in increased phosphorylation of CAMK2A protein]; resveratrol inhibits the reaction [Streptozocin results in increased expression of and results in increased phosphorylation of and results in increased activity of CAMK2A protein]; Streptozocin results in increased expression of and results in increased phosphorylation of and results in increased activity of CAMK2A protein
Ibuprofen inhibits the reaction [Streptozocin results in decreased expression of CAMK2A mRNA]; Ibuprofen inhibits the reaction [Streptozocin results in decreased expression of CAMK2A protein]; Memantine inhibits the reaction [Streptozocin results in decreased expression of CAMK2A mRNA]; Memantine inhibits the reaction [Streptozocin results in decreased expression of CAMK2A protein]
Streptozocin results in decreased expression of CAMK2A mRNA; Streptozocin results in decreased expression of CAMK2A protein
CTD PMID:20424226 PMID:24333387 NCBI chr18:61,058,704...61,121,224
Ensembl chr18:61,058,690...61,121,224
JBrowse link
G Camp cathelicidin antimicrobial peptide multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of CAMP mRNA CTD PMID:33484791 NCBI chr 9:109,676,445...109,678,524
Ensembl chr 9:109,676,447...109,678,685
JBrowse link
G Canx calnexin multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of CANX protein; Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of CANX protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of CANX protein] CTD PMID:34801538 NCBI chr11:50,184,784...50,216,500
Ensembl chr11:50,184,788...50,216,500
JBrowse link
G Capg capping actin protein, gelsolin like multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of CAPG mRNA CTD PMID:25905778 NCBI chr 6:72,515,265...72,539,966
Ensembl chr 6:72,521,374...72,539,966
JBrowse link
G Capn8 calpain 8 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of CAPN8 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CAPN8 mRNA] CTD PMID:33484791 NCBI chr 1:182,392,314...182,462,021
Ensembl chr 1:182,392,572...182,459,917
JBrowse link
G Car3 carbonic anhydrase 3 multiple interactions
decreases expression
ISO [resveratrol co-treated with Streptozocin] results in decreased expression of CAR3 mRNA
Streptozocin results in decreased expression of CAR3 mRNA
CTD PMID:25905778 NCBI chr 3:14,928,598...14,937,441
Ensembl chr 3:14,928,572...14,937,583
JBrowse link
G Cartpt CART prepropeptide decreases expression
multiple interactions
ISO Streptozocin results in decreased expression of CARTPT mRNA
GHRL protein promotes the reaction [Streptozocin results in decreased expression of CARTPT mRNA]
CTD PMID:20219977 NCBI chr13:100,034,991...100,037,191
Ensembl chr13:100,034,997...100,037,599
JBrowse link
G Casp1 caspase 1 multiple interactions
increases expression
ISO
EXP
[Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased cleavage of CASP1 protein]; [Streptozocin co-treated with Dietary Fats] results in increased cleavage of CASP1 protein; Allopurinol inhibits the reaction [Streptozocin results in increased expression of CASP1 mRNA]; Allopurinol inhibits the reaction [Streptozocin results in increased expression of CASP1 protein]; Dimethyl Fumarate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased cleavage of CASP1 protein]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased cleavage of CASP1 protein]; Insulin promotes the reaction [Ozone inhibits the reaction [Streptozocin results in increased expression of CASP1 mRNA]]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased cleavage of CASP1 protein]; Ozone inhibits the reaction [Streptozocin results in increased expression of CASP1 mRNA]; palbinone inhibits the reaction [Streptozocin results in increased expression of and results in increased cleavage of CASP1 protein]; Quercetin inhibits the reaction [Streptozocin results in increased expression of CASP1 mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of CASP1 protein]; scutellarin inhibits the reaction [Streptozocin results in increased expression of CASP1 mRNA]; Streptozocin results in increased expression of and results in increased cleavage of CASP1 protein
Streptozocin results in increased expression of CASP1 mRNA; Streptozocin results in increased expression of CASP1 protein
[aucubin co-treated with Streptozocin co-treated with Dietary Fats] results in decreased cleavage of CASP1 protein; [Dietary Fats co-treated with Streptozocin] results in increased expression of CASP1 protein; [Streptozocin co-treated with Dextran Sulfate] results in increased cleavage of CASP1 protein; [Streptozocin co-treated with Dietary Fats] results in increased activity of CASP1 protein; GSDMD protein affects the reaction [Streptozocin results in increased cleavage of CASP1 protein]; loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CASP1 protein]; NLRP3 protein promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased activity of CASP1 protein]; Streptozocin results in increased expression of and results in increased cleavage of CASP1 protein
CTD PMID:23647015 PMID:26614261 PMID:27783111 PMID:32202043 PMID:34212273 More... NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290
JBrowse link
G Casp12 caspase 12 increases expression
increases cleavage
multiple interactions
EXP
ISO
Streptozocin results in increased expression of CASP12 protein modified form
Streptozocin results in increased cleavage of CASP12 protein
FGF21 protein affects the reaction [Streptozocin results in increased expression of CASP12 protein modified form]; sulforaphane inhibits the reaction [Streptozocin results in increased cleavage of CASP12 protein]
Curcumin inhibits the reaction [Streptozocin results in increased cleavage of CASP12 protein]
CTD PMID:23499715 PMID:24967692 PMID:25541178 NCBI chr 9:5,345,419...5,373,034
Ensembl chr 9:5,345,430...5,373,032
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
decreases cleavage
increases cleavage
increases expression
decreases expression
ISO
EXP
3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of CASP3 protein; [Rolipram co-treated with Pentoxifylline] inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; [Streptozocin co-treated with Arsenic] results in increased expression of CASP3 mRNA; [Streptozocin co-treated with Cadmium] results in increased expression of CASP3 mRNA; [Streptozocin co-treated with IGF2R protein modified form] results in increased expression of CASP3 protein modified form; [Streptozocin co-treated with Lead co-treated with Manganese co-treated with Cadmium co-treated with Arsenic] results in increased expression of CASP3 mRNA; [Streptozocin co-treated with Lead] results in increased expression of CASP3 mRNA; [Streptozocin co-treated with Manganese] results in increased expression of CASP3 mRNA; Acetylcysteine inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; Anthocyanins inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of CASP3 protein]; Curcumin inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; diallyl trisulfide inhibits the reaction [Streptozocin results in decreased cleavage of CASP3 protein]; Ellagic Acid inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; Ellagic Acid promotes the reaction [sinapinic acid inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]]; ferulic acid analog inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of CASP3 protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; Ibuprofen inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; Ibuprofen inhibits the reaction [Streptozocin results in increased expression of CASP3 mRNA]; Imatinib Mesylate inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; Insulin promotes the reaction [Ozone inhibits the reaction [Streptozocin results in increased expression of CASP3 mRNA]]; Memantine inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; Memantine inhibits the reaction [Streptozocin results in increased expression of CASP3 mRNA]; Metformin inhibits the reaction [Streptozocin results in increased expression of CASP3 mRNA]; morin inhibits the reaction [Streptozocin results in increased expression of CASP3 mRNA]; nifuroxazide inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; nifuroxazide inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Ozone inhibits the reaction [Streptozocin results in increased expression of CASP3 mRNA]; Pentoxifylline inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Phosphocreatine inhibits the reaction [Streptozocin results in decreased expression of CASP3 protein]; Phosphocreatine inhibits the reaction [Streptozocin results in increased expression of CASP3 protein modified form]; Propofol inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Rivastigmine inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; Rolipram inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Rosiglitazone inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; sinapinic acid inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; sinapinic acid promotes the reaction [Ellagic Acid inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]]; Streptozocin results in increased expression of and results in increased cleavage of CASP3 protein; Thioctic Acid inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; Tropisetron inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; Vitamin B 12 inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]
Streptozocin analog results in increased activity of CASP3 protein; Streptozocin results in increased activity of CASP3 protein
[Streptozocin co-treated with bisphenol A] results in increased expression of CASP3 mRNA; [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] affects the cleavage of CASP3 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of CASP3 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of CASP3 protein; [Streptozocin co-treated with NQO1 protein mutant form] results in increased expression of CASP3 protein modified form; [Streptozocin co-treated with octylphenol] results in increased expression of CASP3 mRNA; fatostatin promotes the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Metformin inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; montelukast inhibits the reaction [Streptozocin results in increased expression of CASP3 protein modified form]; NTN1 protein inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; phillyrin inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Quercetin inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CASP3 mRNA]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CASP3 protein]; Streptozocin inhibits the reaction [Cisplatin results in increased expression of CASP3 protein]; Streptozocin inhibits the reaction [Ethinyl Estradiol results in decreased expression of CASP3 mRNA]; sulforaphane inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]
Streptozocin results in increased expression of CASP3 mRNA; Streptozocin results in increased expression of CASP3 protein; Streptozocin results in increased expression of CASP3 protein modified form
Streptozocin results in increased expression of CASP3 mRNA; Streptozocin results in increased expression of CASP3 protein modified form
Streptozocin results in decreased expression of CASP3 mRNA; Streptozocin results in decreased expression of CASP3 protein
CTD PMID:12502508 PMID:15976052 PMID:18721751 PMID:18758938 PMID:19133311 More... NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Casp4 caspase 4, apoptosis-related cysteine peptidase increases expression EXP Streptozocin results in increased expression of CASP4 mRNA CTD PMID:34212273 NCBI chr 9:5,308,816...5,336,791
Ensembl chr 9:5,308,828...5,336,783
JBrowse link
G Casp6 caspase 6 increases expression ISO Streptozocin results in increased expression of CASP6 protein CTD PMID:15976052 NCBI chr 3:129,695,064...129,707,761
Ensembl chr 3:129,695,074...129,707,752
JBrowse link
G Casp7 caspase 7 increases expression
multiple interactions
ISO Streptozocin results in increased expression of CASP7 protein
[Streptozocin co-treated with Fructose] results in increased expression of CASP7 protein; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of CASP7 protein]; dapagliflozin promotes the reaction [Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of CASP7 protein]]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of CASP7 protein]; Metformin promotes the reaction [dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of CASP7 protein]]
CTD PMID:15976052 PMID:30551545 NCBI chr19:56,382,640...56,430,780
Ensembl chr19:56,385,561...56,430,776
JBrowse link
G Casp8 caspase 8 multiple interactions
increases expression
increases cleavage
increases activity
ISO Anthocyanins inhibits the reaction [Streptozocin results in increased expression of CASP8 protein]; Curcumin inhibits the reaction [Streptozocin results in increased cleavage of CASP8 protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of CASP8 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of CASP8 mRNA]; nifuroxazide inhibits the reaction [Streptozocin results in increased activity of CASP8 protein]
Streptozocin results in increased expression of CASP8 mRNA; Streptozocin results in increased expression of CASP8 protein
CTD PMID:23267840 PMID:25541178 PMID:28856781 PMID:29606028 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662
JBrowse link
G Casp9 caspase 9 multiple interactions
increases expression
increases activity
decreases expression
ISO
EXP
[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of CASP9 protein; Anthocyanins inhibits the reaction [Streptozocin results in increased expression of CASP9 protein]; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of CASP9 protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of CASP9 protein]; IGF2R protein modified form inhibits the reaction [Streptozocin results in increased expression of CASP9 protein]; Insulin promotes the reaction [Ozone inhibits the reaction [Streptozocin results in increased expression of CASP9 mRNA]]; nifuroxazide inhibits the reaction [Streptozocin results in increased activity of CASP9 protein]; Ozone inhibits the reaction [Streptozocin results in increased expression of CASP9 mRNA]; Phosphocreatine inhibits the reaction [Streptozocin results in decreased expression of CASP9 protein]; Streptozocin results in increased expression of and results in increased cleavage of CASP9 protein; Thioctic Acid inhibits the reaction [Streptozocin results in increased expression of CASP9 protein]
Streptozocin results in increased expression of CASP9 mRNA; Streptozocin results in increased expression of CASP9 protein
[Streptozocin co-treated with Dietary Fats] results in increased expression of CASP9 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of CASP9 protein; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CASP9 mRNA]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CASP9 protein]
CTD PMID:15976052 PMID:19951573 PMID:22940631 PMID:26614261 PMID:28856781 More... NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
JBrowse link
G Cat catalase increases expression
multiple interactions
decreases response to substance
increases phosphorylation
decreases expression
increases activity
decreases activity
EXP
ISO
Streptozocin results in increased expression of CAT mRNA
Streptozocin results in increased expression of CAT protein
CAT protein promotes the reaction [SOD2 protein results in decreased susceptibility to Streptozocin]; SOD2 protein promotes the reaction [CAT protein results in decreased susceptibility to Streptozocin]
Streptozocin results in increased phosphorylation of CAT protein
Streptozocin results in decreased expression of CAT; Streptozocin results in decreased expression of CAT mRNA
2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; [Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein; [Dietary Fats co-treated with Streptozocin] results in decreased expression of CAT mRNA; [Streptozocin co-treated with Dextran Sulfate] results in decreased expression of CAT protein; [Streptozocin co-treated with Dietary Fats] results in decreased activity of CAT protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein; [Streptozocin co-treated with INS1 protein co-treated with Glutathione] affects the expression of CAT mRNA; [Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein; Acrylamide promotes the reaction [Streptozocin results in decreased activity of CAT protein]; Alendronate inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein]; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein]; Donepezil inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; pterostilbene inhibits the reaction [Streptozocin results in decreased expression of CAT]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; rhodioloside inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of CAT mRNA]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of CAT protein]
Streptozocin results in decreased expression of CAT mRNA; Streptozocin results in decreased expression of CAT protein
1,3-dimethoxy-5-methyl-2-(3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl)benzene inhibits the reaction [4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in increased expression of CAT protein]]; 2-hydroxy-4-methoxy benzoic acid inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; 4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in increased expression of CAT protein]; 4-methyl-2-((2-methylbenzyl) amino)-1,3-thiazole-5-carboxylic acid inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; 5,3'-dihydroxy-3,6,7,4',5'-pentamethoxyflavone inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; [Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein; [Dietary Fats co-treated with Streptozocin] results in decreased expression of CAT protein; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein; [Fructose co-treated with Streptozocin] results in decreased activity of CAT protein; [Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein]; [Niacinamide co-treated with Streptozocin] results in decreased activity of CAT protein; [Phytic Acid co-treated with Inositol] inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; [pimagedine co-treated with Fatty Acids, Omega-3] inhibits the reaction [Streptozocin results in increased activity of CAT protein]; [Propolis co-treated with Chlorpyrifos co-treated with Streptozocin] results in increased activity of CAT protein; [Propolis co-treated with Streptozocin] results in increased activity of CAT protein; [Quercetin co-treated with coenzyme Q10] inhibits the reaction [Streptozocin results in increased activity of CAT protein]; [Quercetin co-treated with Streptozocin] results in increased activity of CAT protein; [Rosiglitazone co-treated with Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein; [Streptozocin co-treated with bisphenol A] results in decreased expression of CAT protein; [Streptozocin co-treated with Chlorpyrifos] results in increased activity of CAT protein; [Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the activity of CAT protein; [Streptozocin co-treated with Dietary Fats] results in decreased activity of CAT protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein; [Streptozocin co-treated with Isoproterenol] affects the activity of CAT protein; [Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of CAT protein; [Zinc co-treated with Selenium] inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; [Zinc Sulfate results in increased abundance of Zinc] inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; allyl methyl sulfide inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; alpha-Tocopherol inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; arjunolic acid inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; asiatic acid inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Berberine affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the activity of CAT protein]; Bezafibrate inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein]; caryophyllene inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; CAT protein inhibits the reaction [Streptozocin results in increased expression of GNA11 protein]; CAT protein inhibits the reaction [Streptozocin results in increased expression of GNAQ protein]; CAT protein inhibits the reaction [Streptozocin results in increased expression of PLCB1 protein]; CAT protein inhibits the reaction [Streptozocin results in increased expression of PLCB2 protein]; Chlorpyrifos promotes the reaction [Streptozocin results in increased activity of CAT protein]; Chromium inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; chromium tripicolinate inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; corilagin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; coumarin inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in decreased activity of CAT protein]; crocin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; dapagliflozin inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; Diltiazem inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Dimethyl Fumarate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein]; Diosmin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of CAT mRNA]; Ellagic Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein]; eupafolin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of CAT protein]; fenugreek seed meal inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Ficusin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased activity of CAT protein]; Gallic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased activity of CAT protein]; Gallic Acid inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; geraniol inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Gliclazide inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in decreased activity of CAT protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; Gliclazide inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein]; Glyburide inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; hesperetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein]; Imatinib Mesylate inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Imipramine inhibits the reaction [Streptozocin results in increased activity of CAT protein]; INS1 protein inhibits the reaction [Streptozocin results in increased activity of CAT protein]; isoquercitrin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Losartan inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; mangiferin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Melatonin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Metformin inhibits the reaction [[Fructose co-treated with Streptozocin] results in decreased activity of CAT protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein]; Metformin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Metformin inhibits the reaction [Streptozocin results in decreased expression of CAT mRNA]; morin analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased activity of CAT protein]; morin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; myrsinoic acid B inhibits the reaction [Streptozocin results in increased activity of CAT protein]; myrtenol inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; naringenin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; nerolidol inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein]; notoginsenoside R1 inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; palbinone inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; pinitol inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Pioglitazone inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased activity of CAT protein]; Pioglitazone inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; Pioglitazone inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; piperlongumine inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; Plant Extracts inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein]; Propolis inhibits the reaction [[Streptozocin co-treated with Chlorpyrifos] results in increased activity of CAT protein]; Propolis inhibits the reaction [Streptozocin results in increased activity of CAT protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of CAT protein]; Quercetin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Quercetin inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; Quercetin inhibits the reaction [Streptozocin results in increased activity of CAT protein]; Resveratrol inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in decreased activity of CAT protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of and results in decreased activity of CAT protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of CAT mRNA]; Resveratrol promotes the reaction [Streptozocin results in decreased expression of CAT mRNA]; rhapontin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Rosiglitazone affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the activity of CAT protein]; S-allylcysteine inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; Saponins inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; sodium arsenate promotes the reaction [Streptozocin results in decreased activity of CAT protein]; Sodium Selenite inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Streptozocin inhibits the reaction [Lipopolysaccharides results in increased expression of CAT protein]; Streptozocin inhibits the reaction [Streptozocin results in increased expression of CAT protein]; Streptozocin promotes the reaction [Chlorpyrifos results in increased activity of CAT protein]; Streptozocin results in decreased expression of and results in decreased activity of CAT protein; Streptozocin results in increased expression of and results in increased activity of CAT protein; Thioctic Acid inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; thymoquinone inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; Tocotrienols inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; U 78517F inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; vanillin inhibits the reaction [[Fructose co-treated with Streptozocin] results in decreased activity of CAT protein]; Zinc Compounds inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased activity of CAT protein]; Zinc inhibits the reaction [Streptozocin results in decreased activity of CAT protein]
CTD PMID:9522273 PMID:11424224 PMID:12123627 PMID:12242689 PMID:15298345 More... NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Cav1 caveolin 1, caveolae protein multiple interactions
increases expression
ISO resveratrol inhibits the reaction [Streptozocin promotes the reaction [CAV1 protein binds to NOS3 protein]]; resveratrol inhibits the reaction [Streptozocin results in increased expression of CAV1 protein]; Streptozocin promotes the reaction [CAV1 protein binds to NOS3 protein] CTD PMID:18266981 NCBI chr 6:17,306,387...17,341,323
Ensembl chr 6:17,306,334...17,341,451
JBrowse link
G Cav3 caveolin 3 multiple interactions
decreases expression
ISO resveratrol inhibits the reaction [Streptozocin inhibits the reaction [CAV3 protein binds to SLC2A4 protein]]; resveratrol inhibits the reaction [Streptozocin results in decreased expression of CAV3 protein]; Streptozocin inhibits the reaction [CAV3 protein binds to SLC2A4 protein] CTD PMID:18266981 NCBI chr 6:112,436,466...112,449,833
Ensembl chr 6:112,436,466...112,449,833
JBrowse link
G Cbr1 carbonyl reductase 1 decreases activity ISO Streptozocin results in decreased activity of CBR1 protein CTD PMID:11057757 NCBI chr16:93,404,752...93,407,226
Ensembl chr16:93,402,741...93,407,393
JBrowse link
G Cbs cystathionine beta-synthase multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of CBS mRNA CTD PMID:29127188 NCBI chr17:31,831,602...31,856,170
Ensembl chr17:31,827,868...31,856,212
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression
affects response to substance
multiple interactions
increases secretion
EXP
ISO
Streptozocin results in increased expression of CCL2; Streptozocin results in increased expression of CCL2 mRNA; Streptozocin results in increased expression of CCL2 protein
CCL2 affects the susceptibility to Streptozocin
[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of CCL2 protein; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of CCL2 protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; Flavonoids inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of CCL2 protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; moutan cortex inhibits the reaction [Streptozocin results in increased expression of and results in increased secretion of CCL2 protein]; Mycophenolic Acid inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; Mycophenolic Acid inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]; PD 123319 inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; Pentoxifylline inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]; procyanidin B2 inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; prolinedithiocarbamate inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]; Rosiglitazone inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; Streptozocin results in increased expression of and results in increased secretion of CCL2 protein; Valsartan inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]; vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]
4-(4-(3-adamantan-1-ylureido)cyclohexyloxy)benzoic acid inhibits the reaction [Streptozocin results in increased secretion of CCL2 protein]; [AM6545 co-treated with Perindopril] inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; [AM6545 co-treated with Perindopril] inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of CCL2 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of CCL2 protein; [fatostatin co-treated with Streptozocin] results in increased expression of CCL2 protein; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of CCL2 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased secretion of CCL2 protein; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased secretion of CCL2 protein]; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]; EPHX2 gene mutant form inhibits the reaction [Streptozocin results in increased secretion of CCL2 protein]; esculetin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CCL2 protein]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CCL2 mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of CCL2 mRNA]; stannous mesoporphyrin inhibits the reaction [4-(4-(3-adamantan-1-ylureido)cyclohexyloxy)benzoic acid inhibits the reaction [Streptozocin results in increased secretion of CCL2 protein]]; Valsartan inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]
CTD PMID:15284299 PMID:16374426 PMID:16684804 PMID:17624267 PMID:18413206 More... NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions
increases expression
EXP AM6545 inhibits the reaction [Streptozocin results in increased expression of CCL3 mRNA]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in increased expression of CCL3 mRNA]]; Perindopril inhibits the reaction [Streptozocin results in increased expression of CCL3 mRNA]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in increased expression of CCL3 mRNA]] CTD PMID:30184259 NCBI chr11:83,538,669...83,540,204
Ensembl chr11:83,538,670...83,540,181
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression EXP Streptozocin results in increased expression of CCL5 mRNA CTD PMID:29420703 NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344
JBrowse link
G Ccl6 C-C motif chemokine ligand 6 multiple interactions ISO [Resveratrol co-treated with Streptozocin] results in increased expression of CCL6 mRNA CTD PMID:25905778 NCBI chr11:83,478,712...83,483,913
Ensembl chr11:83,478,708...83,483,913
JBrowse link
G Ccn2 cellular communication network factor 2 increases expression
multiple interactions
EXP
ISO
Streptozocin results in increased expression of CCN2; Streptozocin results in increased expression of CCN2 protein
[Streptozocin co-treated with Resveratrol co-treated with Ramipril] results in decreased expression of CCN2 protein; Acetylcysteine inhibits the reaction [Streptozocin results in increased expression of CCN2 protein]; Aspirin inhibits the reaction [Streptozocin results in increased expression of CCN2 mRNA]; Enalapril inhibits the reaction [Streptozocin results in increased expression of CCN2 protein]; fenugreek seed meal inhibits the reaction [Streptozocin results in increased expression of CCN2 mRNA]; fenugreek seed meal inhibits the reaction [Streptozocin results in increased expression of CCN2 protein]; idebenone inhibits the reaction [Streptozocin results in increased expression of CCN2 protein]; XLF-III-43 inhibits the reaction [Streptozocin results in increased expression of CCN2 protein]; Zinc inhibits the reaction [Streptozocin results in increased expression of CCN2 protein]
[Dietary Fats co-treated with Streptozocin] promotes the reaction [KLF15 gene mutant form results in increased expression of CCN2 protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of CCN2 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of CCN2 protein; CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CCN2 protein]; KLF15 gene mutant form inhibits the reaction [CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CCN2 protein]]; KLF15 gene mutant form promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CCN2 protein]; sulforaphane inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CCN2 protein]; sulforaphane inhibits the reaction [Streptozocin results in increased expression of CCN2 protein]
Streptozocin results in increased expression of CCN2 mRNA; Streptozocin results in increased expression of CCN2 protein
CTD PMID:10026205 PMID:14586741 PMID:17270171 PMID:19369054 PMID:19657322 More... NCBI chr10:24,471,340...24,474,581
Ensembl chr10:24,471,340...24,474,581
JBrowse link
G Ccnd1 cyclin D1 decreases expression
multiple interactions
EXP Streptozocin results in decreased expression of CCND1 mRNA
5-Methoxypsoralen inhibits the reaction [Streptozocin results in decreased expression of CCND1 mRNA]; Tadalafil inhibits the reaction [Streptozocin results in decreased expression of CCND1 mRNA]
CTD PMID:34428446 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662
JBrowse link
G Ccnd2 cyclin D2 decreases expression
multiple interactions
EXP Streptozocin results in decreased expression of CCND2 protein
AM 251 inhibits the reaction [Streptozocin results in decreased expression of CCND2 protein]; CNR1 protein promotes the reaction [Streptozocin results in decreased expression of CCND2 protein]
CTD PMID:26967640 NCBI chr 6:127,102,125...127,131,913
Ensembl chr 6:127,102,125...127,129,156
JBrowse link
G Ccnt1 cyclin T1 multiple interactions ISO [Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 mRNA; [Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 protein; Berberine affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 mRNA]; Berberine affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 protein]; Fenofibrate affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 mRNA]; Fenofibrate affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 protein]; rosiglitazone affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 mRNA]; rosiglitazone affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 protein] CTD PMID:20828602 NCBI chr15:98,436,570...98,468,340
Ensembl chr15:98,436,570...98,468,804
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 multiple interactions
increases expression
EXP [AM6545 co-treated with Perindopril] inhibits the reaction [Streptozocin results in increased expression of CCR2 mRNA]; AM6545 inhibits the reaction [Streptozocin results in increased expression of CCR2 mRNA]; Perindopril inhibits the reaction [Streptozocin results in increased expression of CCR2 mRNA] CTD PMID:30184259 NCBI chr 9:123,901,954...123,913,594
Ensembl chr 9:123,901,987...123,913,594
JBrowse link
G Ccs copper chaperone for superoxide dismutase decreases expression
multiple interactions
ISO Streptozocin results in decreased expression of CCS mRNA; Streptozocin results in decreased expression of CCS protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of CCS mRNA]; Trientine inhibits the reaction [Streptozocin results in decreased expression of CCS protein]
CTD PMID:24927960 NCBI chr19:4,875,394...4,889,326
Ensembl chr19:4,875,394...4,889,360
JBrowse link
G Cd14 CD14 antigen multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of CD14 mRNA CTD PMID:29127188 NCBI chr18:36,858,117...36,859,868
Ensembl chr18:36,858,120...36,859,851
JBrowse link
G Cd163 CD163 antigen multiple interactions
decreases expression
ISO
EXP
[resveratrol co-treated with Streptozocin] results in increased expression of CD163 mRNA
Streptozocin results in decreased expression of CD163 mRNA
AM6545 inhibits the reaction [Streptozocin results in decreased expression of CD163 mRNA]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in decreased expression of CD163 mRNA]]; Perindopril inhibits the reaction [Streptozocin results in decreased expression of CD163 mRNA]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in decreased expression of CD163 mRNA]]
CTD PMID:25905778 PMID:30184259 NCBI chr 6:124,281,596...124,307,488
Ensembl chr 6:124,281,615...124,307,486
JBrowse link
G Cd200r4 CD200 receptor 4 multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of CD200R1L mRNA CTD PMID:25905778 NCBI chr16:44,632,036...44,659,497
Ensembl chr16:44,632,096...44,659,513
JBrowse link
G Cd24a CD24a antigen multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of CD24A mRNA CTD PMID:29127188 NCBI chr10:43,454,433...43,460,261
Ensembl chr10:43,454,280...43,460,261
JBrowse link
G Cd36 CD36 molecule multiple interactions
increases expression
EXP [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of CD36 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of CD36 mRNA; Acrylamide inhibits the reaction [Streptozocin results in increased expression of CD36 mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of CD36 mRNA] CTD PMID:29127188 PMID:34896238 PMID:39047806 NCBI chr 5:17,986,680...18,093,828
Ensembl chr 5:17,986,688...18,093,799
JBrowse link
G Cd53 CD53 antigen multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of CD53 mRNA CTD PMID:25905778 NCBI chr 3:106,666,177...106,697,465
Ensembl chr 3:106,667,237...106,697,465
JBrowse link
G Cd5l CD5 antigen-like multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of CD5L mRNA CTD PMID:25905778 NCBI chr 3:87,265,188...87,278,381
Ensembl chr 3:87,265,188...87,278,380
JBrowse link
G Cd68 CD68 antigen multiple interactions
increases expression
ISO
EXP
[resveratrol co-treated with Streptozocin] results in increased expression of CD68 mRNA; nifuroxazide inhibits the reaction [Streptozocin results in increased expression of CD68 protein]
[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of CD68 mRNA; AM6545 inhibits the reaction [Streptozocin results in increased expression of CD68 mRNA]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in increased expression of CD68 mRNA]]; Perindopril inhibits the reaction [Streptozocin results in increased expression of CD68 mRNA]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in increased expression of CD68 mRNA]]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of CD68 mRNA]
CTD PMID:25905778 PMID:29291386 PMID:30184259 PMID:39047806 NCBI chr11:69,555,039...69,556,996
Ensembl chr11:69,555,039...69,556,979
JBrowse link
G Cd80 CD80 antigen multiple interactions
increases expression
EXP Clodronic Acid inhibits the reaction [Streptozocin results in increased expression of CD80 protein] CTD PMID:15892581 NCBI chr16:38,277,793...38,316,682
Ensembl chr16:38,275,923...38,316,697
JBrowse link
G Cd86 CD86 antigen multiple interactions
increases expression
EXP
ISO
Clodronic Acid inhibits the reaction [Streptozocin results in increased expression of CD86 protein]
[resveratrol co-treated with Streptozocin] results in increased expression of CD86 mRNA
CTD PMID:15892581 PMID:25905778 NCBI chr16:36,389,318...36,486,439
Ensembl chr16:36,424,231...36,486,443
JBrowse link
G Cdca2 cell division cycle associated 2 multiple interactions EXP [Diethylhexyl Phthalate co-treated with Streptozocin co-treated with Dietary Fats] results in increased expression of CDCA2 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of CDCA2 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CDCA2 mRNA] CTD PMID:33484791 NCBI chr14:67,910,629...67,953,290
Ensembl chr14:67,913,780...67,953,290
JBrowse link
G Cdcp3 CUB domain containing protein 3 multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of CDCP3 mRNA CTD PMID:33484791 NCBI chr 7:130,776,131...130,908,181
Ensembl chr 7:130,776,131...130,908,180
JBrowse link
G Cdh1 cadherin 1 decreases expression ISO Streptozocin results in decreased expression of CDH1 CTD PMID:32469605 NCBI chr 8:107,329,982...107,396,879
Ensembl chr 8:107,329,983...107,396,878
JBrowse link
G Cdh2 cadherin 2 multiple interactions
decreases expression
EXP rhodioloside inhibits the reaction [Streptozocin results in decreased expression of CDH2 protein] CTD PMID:31682803 NCBI chr18:16,721,934...16,942,303
Ensembl chr18:16,721,934...16,942,303
JBrowse link
G Cdk15 cyclin dependent kinase 15 multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of CDK15 mRNA CTD PMID:33484791 NCBI chr 1:59,296,029...59,391,656
Ensembl chr 1:59,296,065...59,392,152
JBrowse link
G Cdk9 cyclin dependent kinase 9 multiple interactions
increases phosphorylation
ISO
EXP
[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 mRNA; [Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 protein; Berberine affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 mRNA]; Berberine affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 protein]; Fenofibrate affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 mRNA]; Fenofibrate affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 protein]; rosiglitazone affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 mRNA]; rosiglitazone affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 protein]
Streptozocin results in increased phosphorylation of CDK9 protein
CTD PMID:20828602 PMID:33631230 NCBI chr 2:32,595,794...32,608,098
Ensembl chr 2:32,595,796...32,603,088
JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A multiple interactions
increases expression
EXP
ISO
2-amino-6-boronohexanoic acid inhibits the reaction [Streptozocin results in increased expression of CDKN1A mRNA]; [Dietary Fats co-treated with Streptozocin] results in increased expression of CDKN1A protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of CDKN1A mRNA; Quercetin inhibits the reaction [Streptozocin results in increased expression of CDKN1A mRNA]; SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of CDKN1A]
Streptozocin results in increased expression of CDKN1A; Streptozocin results in increased expression of CDKN1A mRNA
Streptozocin results in increased expression of CDKN1A mRNA; Streptozocin results in increased expression of CDKN1A protein
Organoselenium Compounds inhibits the reaction [Streptozocin results in increased expression of CDKN1A protein]; Streptozocin promotes the reaction [SETD7 protein binds to CDKN1A promoter]
CTD PMID:19496084 PMID:22744176 PMID:25301743 PMID:27652271 PMID:29127188 More... NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701
JBrowse link
G Cdkn2a cyclin dependent kinase inhibitor 2A increases expression
multiple interactions
EXP Streptozocin results in increased expression of CDKN2A mRNA; Streptozocin results in increased expression of CDKN2A protein
2-amino-6-boronohexanoic acid inhibits the reaction [Streptozocin results in increased expression of CDKN2A mRNA]; 2-amino-6-boronohexanoic acid inhibits the reaction [Streptozocin results in increased expression of CDKN2A protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of CDKN2A protein; NTN1 protein inhibits the reaction [Streptozocin results in increased expression of CDKN2A mRNA]; NTN1 protein inhibits the reaction [Streptozocin results in increased expression of CDKN2A protein]
CTD PMID:29059224 PMID:29673160 PMID:38483099 NCBI chr 4:89,192,710...89,212,856
Ensembl chr 4:89,192,708...89,212,890
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions
decreases expression
EXP CEBPB protein affects the reaction [Streptozocin results in increased expression of AGT protein]; CEBPB protein affects the reaction [Streptozocin results in increased expression of TGFB1 protein]; CEBPB protein inhibits the reaction [Streptozocin results in decreased abundance of AGT protein modified form]; CEBPB protein inhibits the reaction [Streptozocin results in decreased abundance of angiotensin I (1-7)]; CEBPB protein inhibits the reaction [Streptozocin results in decreased expression of ACE2 protein]; CEBPB protein inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; CEBPB protein inhibits the reaction [Streptozocin results in decreased expression of MAS1 protein]; CEBPB protein inhibits the reaction [Streptozocin results in decreased expression of MMP2 protein]; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of ACE protein]; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of AGTR1 protein]; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of AGTR2 protein]; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of BAX protein]; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of IL6 protein]
Streptozocin results in decreased expression of CEBPB protein
CTD PMID:29266779 NCBI chr 2:167,530,835...167,532,352
Ensembl chr 2:167,530,835...167,532,338
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of CEBPD mRNA CTD PMID:25905778 NCBI chr16:15,705,150...15,707,409
Ensembl chr16:15,705,150...15,708,895
JBrowse link
G Celf2 CUGBP, Elav-like family member 2 multiple interactions EXP [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of CELF2 mRNA]; [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of CELF2 protein]; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of CELF2 mRNA; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of CELF2 protein CTD PMID:38282657 NCBI chr 2:6,544,505...7,401,345
Ensembl chr 2:6,544,505...7,514,374
JBrowse link
G Celf4 CUGBP, Elav-like family member 4 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of CELF4 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CELF4 mRNA] CTD PMID:33484791 NCBI chr18:25,610,677...25,887,577
Ensembl chr18:25,610,689...25,887,214
JBrowse link
G Ces2c carboxylesterase 2C multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of CES2C mRNA CTD PMID:25905778 NCBI chr 8:105,573,700...105,581,115
Ensembl chr 8:105,573,700...105,581,115
JBrowse link
G Ces2d-ps carboxylesterase 2D, pseudogene multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of CES2D-PS mRNA CTD PMID:33484791 NCBI chr 8:105,594,056...105,600,715
Ensembl chr 8:105,594,120...105,600,493
JBrowse link
G Ces4a carboxylesterase 4A multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of CES4A mRNA CTD PMID:33484791 NCBI chr 8:105,858,432...105,876,741
Ensembl chr 8:105,858,432...105,876,741
JBrowse link
G Cfap45 cilia and flagella associated protein 45 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of CFAP45 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CFAP45 mRNA] CTD PMID:33484791 NCBI chr 1:172,348,697...172,373,437
Ensembl chr 1:172,348,368...172,373,437
JBrowse link
G Cfap69 cilia and flagella associated protein 69 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of CFAP69 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CFAP69 mRNA] CTD PMID:33484791 NCBI chr 5:5,629,284...5,714,232
Ensembl chr 5:5,629,278...5,714,239
JBrowse link
G Cfd complement factor D increases expression ISO Streptozocin results in increased expression of CFD mRNA CTD PMID:3299706 NCBI chr10:79,726,687...79,728,489
Ensembl chr10:79,726,687...79,728,489
JBrowse link
G Cfl1 cofilin 1, non-muscle multiple interactions
increases phosphorylation
ISO fasudil inhibits the reaction [Streptozocin results in increased phosphorylation of CFL1 protein] CTD PMID:22062134 NCBI chr19:5,540,483...5,544,059
Ensembl chr19:5,540,483...5,545,229
JBrowse link
G Cfp complement factor properdin multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of CFP mRNA CTD PMID:25905778 NCBI chr  X:20,791,693...20,797,794
Ensembl chr  X:20,791,693...20,797,794
JBrowse link
G Chat choline O-acetyltransferase multiple interactions
affects localization
decreases expression
ISO Inositol inhibits the reaction [Streptozocin affects the localization of CHAT protein]; Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of CHAT protein]; Rivastigmine inhibits the reaction [Streptozocin results in decreased expression of CHAT protein] CTD PMID:2431858 PMID:32805344 NCBI chr14:32,130,160...32,187,866
Ensembl chr14:32,130,160...32,187,946
JBrowse link
G Chga chromogranin A multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of CHGA mRNA CTD PMID:33484791 NCBI chr12:102,521,200...102,531,286
Ensembl chr12:102,521,228...102,531,287
JBrowse link
G Chil3 chitinase-like 3 multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of CHIL3 mRNA CTD PMID:33484791 NCBI chr 3:106,054,870...106,074,852
Ensembl chr 3:106,054,870...106,074,880
JBrowse link
G Chka choline kinase alpha multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of CHKA mRNA CTD PMID:29127188 NCBI chr19:3,901,585...3,944,368
Ensembl chr19:3,901,773...3,944,369
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2, cardiac multiple interactions
affects expression
increases expression
ISO 1-hexacosanol inhibits the reaction [Streptozocin affects the expression of CHRM2 mRNA]; Phlorhizin inhibits the reaction [Streptozocin results in increased expression of CHRM2 mRNA]; Phlorhizin inhibits the reaction [Streptozocin results in increased expression of CHRM2 protein]
Streptozocin results in increased expression of CHRM2 mRNA; Streptozocin results in increased expression of CHRM2 protein
CTD PMID:17989502 PMID:18715473 NCBI chr 6:36,364,928...36,505,573
Ensembl chr 6:36,365,019...36,505,349
JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3, cardiac multiple interactions
affects expression
ISO 1-hexacosanol inhibits the reaction [Streptozocin affects the expression of CHRM3 mRNA] CTD PMID:17989502 NCBI chr13:9,925,522...10,411,131
Ensembl chr13:9,925,522...10,410,883
JBrowse link
G Chrna4 cholinergic receptor, nicotinic, alpha polypeptide 4 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of CHRNA4 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CHRNA4 mRNA] CTD PMID:33484791 NCBI chr 2:180,664,104...180,685,339
Ensembl chr 2:180,660,173...180,685,339
JBrowse link
G Chst8 carbohydrate sulfotransferase 8 multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of CHST8 mRNA CTD PMID:33484791 NCBI chr 7:34,373,893...34,512,136
Ensembl chr 7:34,373,893...34,512,136
JBrowse link
G Chuk conserved helix-loop-helix ubiquitous kinase multiple interactions
increases expression
ISO Quercetin inhibits the reaction [Streptozocin results in increased expression of CHUK protein] CTD PMID:16177186 NCBI chr19:44,061,773...44,095,940
Ensembl chr19:44,061,774...44,095,919
JBrowse link
G Cidea cell death-inducing DNA fragmentation factor, alpha subunit-like effector A multiple interactions ISO
EXP
[resveratrol co-treated with Streptozocin] results in increased expression of CIDEA mRNA
[Streptozocin co-treated with Dietary Fats] results in increased expression of CIDEA mRNA
CTD PMID:25905778 PMID:29127188 NCBI chr18:67,476,634...67,500,864
Ensembl chr18:67,476,674...67,500,855
JBrowse link
G Cisd1 CDGSH iron sulfur domain 1 increases expression
multiple interactions
ISO Streptozocin results in increased expression of CISD1 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of CISD1 protein]
CTD PMID:19634143 NCBI chr10:71,166,324...71,180,679
Ensembl chr10:71,166,310...71,180,784
JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 increases expression
multiple interactions
decreases expression
ISO
EXP
Streptozocin results in increased expression of CITED2 mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of CITED2 mRNA]
SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of CITED2 mRNA]
CTD PMID:16684804 PMID:27629361 NCBI chr10:17,598,452...17,601,422
Ensembl chr10:17,598,966...17,601,422
JBrowse link
G Ckmt2 creatine kinase, mitochondrial 2 multiple interactions
decreases expression
ISO vanadyl sulfate inhibits the reaction [Streptozocin results in decreased expression of CKMT2 mRNA] CTD PMID:16684804 NCBI chr13:92,001,510...92,025,001
Ensembl chr13:92,001,506...92,025,004
JBrowse link
G Cldn1 claudin 1 decreases expression ISO Streptozocin results in decreased expression of CLDN1 mRNA CTD PMID:25905778 NCBI chr16:26,175,395...26,190,589
Ensembl chr16:26,175,392...26,190,591
JBrowse link
G Cldn11 claudin 11 multiple interactions
decreases expression
EXP rhodioloside inhibits the reaction [Streptozocin results in decreased expression of CLDN11 protein] CTD PMID:31682803 NCBI chr 3:31,204,069...31,218,475
Ensembl chr 3:31,204,069...31,218,473
JBrowse link
G Cldn2 claudin 2 decreases expression ISO Streptozocin results in decreased expression of CLDN2 mRNA CTD PMID:25905778 NCBI chr  X:138,701,552...138,712,135
Ensembl chr  X:138,701,577...138,712,135
JBrowse link
G Clec4d C-type lectin domain family 4, member d multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of CLEC4D mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CLEC4D mRNA] CTD PMID:33484791 NCBI chr 6:123,239,066...123,252,227
Ensembl chr 6:123,239,070...123,252,224
JBrowse link
G Clec4f C-type lectin domain family 4, member f multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of CLEC4F mRNA CTD PMID:25905778 NCBI chr 6:83,621,524...83,633,098
Ensembl chr 6:83,621,524...83,633,169
JBrowse link
G Clic4 chloride intracellular channel 4 affects expression EXP Streptozocin affects the expression of CLIC4 mRNA CTD PMID:18583417 NCBI chr 4:134,941,280...135,000,071
Ensembl chr 4:134,941,280...135,000,125
JBrowse link
G Clpp caseinolytic mitochondrial matrix peptidase proteolytic subunit affects expression EXP Streptozocin affects the expression of CLPP mRNA CTD PMID:18583417 NCBI chr17:57,297,264...57,303,371
Ensembl chr17:57,297,305...57,303,188
JBrowse link
G Clu clusterin increases expression
multiple interactions
ISO Streptozocin results in increased expression of CLU protein
Trientine inhibits the reaction [Streptozocin results in increased expression of CLU protein]
CTD PMID:19634143 NCBI chr14:66,206,093...66,218,992
Ensembl chr14:66,205,932...66,218,996
JBrowse link
G Cnpy1 canopy FGF signaling regulator 1 multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of CNPY1 mRNA CTD PMID:33484791 NCBI chr 5:28,405,817...28,450,786
Ensembl chr 5:28,405,817...28,450,804
JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions
decreases expression
increases expression
ISO
EXP
[Fructose co-treated with Streptozocin] results in decreased expression of CNR1 mRNA; Ghrelin inhibits the reaction [[Fructose co-treated with Streptozocin] results in decreased expression of CNR1 mRNA]
Streptozocin results in decreased expression of CNR1 protein
Streptozocin results in increased expression of CNR1 mRNA; Streptozocin results in increased expression of CNR1 protein
[Streptozocin co-treated with CNR1 protein] affects the expression of IGF1R protein; [Streptozocin co-treated with CNR1 protein] affects the phosphorylation of AKT1 protein; CNR1 protein promotes the reaction [Streptozocin results in decreased expression of BCL2 protein]; CNR1 protein promotes the reaction [Streptozocin results in decreased expression of CCND2 protein]; CNR1 protein promotes the reaction [Streptozocin results in decreased expression of INS1 protein]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of CNR1 mRNA]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of CNR1 protein]
CTD PMID:26967640 PMID:30184259 PMID:30642005 PMID:30721768 PMID:31468622 NCBI chr 4:33,923,171...33,948,831
Ensembl chr 4:33,924,593...33,948,831
JBrowse link
G Col1a1 collagen, type I, alpha 1 multiple interactions
increases expression
EXP [Dietary Fats co-treated with Streptozocin] results in increased expression of COL1A1 mRNA; Curcumin analog inhibits the reaction [Streptozocin results in increased expression of COL1A1 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of COL1A1 mRNA]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of COL1A1 mRNA] CTD PMID:28700904 PMID:29988851 NCBI chr11:94,827,050...94,843,868
Ensembl chr11:94,827,050...94,843,868
JBrowse link
G Col3a1 collagen, type III, alpha 1 multiple interactions
increases expression
EXP
ISO
[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of COL3A1 mRNA; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of COL3A1 mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of COL3A1 protein]
INS1 protein inhibits the reaction [Streptozocin results in increased expression of COL3A1 protein]
CTD PMID:29266779 PMID:29682576 PMID:39047806 NCBI chr 1:45,350,698...45,388,866
Ensembl chr 1:45,350,698...45,388,866
JBrowse link
G Col4a1 collagen, type IV, alpha 1 decreases expression
increases expression
multiple interactions
EXP
ISO
Streptozocin results in decreased expression of COL4A1 mRNA
Streptozocin results in increased expression of COL4A1 mRNA
benazepril inhibits the reaction [Streptozocin results in increased expression of COL4A1 mRNA]; MFN2 protein mutant form inhibits the reaction [Streptozocin promotes the reaction [TFAP2A protein binds to COL4A1 promoter]]; MFN2 protein mutant form inhibits the reaction [Streptozocin results in increased expression of COL4A1 mRNA]; Streptozocin promotes the reaction [TFAP2A protein binds to COL4A1 promoter]
[fatostatin co-treated with Streptozocin] results in increased expression of COL4A1 mRNA
CTD PMID:11798618 PMID:15496156 PMID:17582205 PMID:27997345 PMID:29420703 NCBI chr 8:11,248,423...11,362,889
Ensembl chr 8:11,248,423...11,362,826
JBrowse link
G Col4a2 collagen, type IV, alpha 2 increases expression
multiple interactions
EXP Streptozocin results in increased expression of COL4A2 mRNA
MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of COL4A2 mRNA]
CTD PMID:30642005 NCBI chr 8:11,362,878...11,499,287
Ensembl chr 8:11,362,805...11,499,287
JBrowse link
G Col4a3 collagen, type IV, alpha 3 multiple interactions
increases expression
ISO Zinc inhibits the reaction [Streptozocin results in increased expression of COL4A3 mRNA] CTD PMID:31009641 NCBI chr 1:82,564,647...82,699,778
Ensembl chr 1:82,564,642...82,699,780
JBrowse link
G Col4a4 collagen, type IV, alpha 4 multiple interactions
increases expression
EXP 3-((6-(2-methoxyphenyl)pyrimidin-4-yl)amino)phenyl)methane sulfonamide inhibits the reaction [Streptozocin results in increased expression of COL4A4 mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of COL4A4 mRNA] CTD PMID:33631230 NCBI chr 1:82,426,140...82,564,570
Ensembl chr 1:82,426,144...82,564,570
JBrowse link
G Col6a1 collagen, type VI, alpha 1 increases expression
multiple interactions
ISO Streptozocin results in increased expression of COL6A1 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of COL6A1 protein]
CTD PMID:19634143 NCBI chr10:76,544,626...76,561,869
Ensembl chr10:76,544,626...76,562,002
JBrowse link
G Col6a2 collagen, type VI, alpha 2 increases expression
multiple interactions
ISO Streptozocin results in increased expression of COL6A2 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of COL6A2 protein]
CTD PMID:19634143 NCBI chr10:76,431,590...76,459,464
Ensembl chr10:76,431,596...76,459,464
JBrowse link
G Col6a3 collagen, type VI, alpha 3 increases expression
multiple interactions
ISO Streptozocin results in increased expression of COL6A3 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of COL6A3 protein]
CTD PMID:19634143 NCBI chr 1:90,694,582...90,771,710
Ensembl chr 1:90,693,645...90,771,693
JBrowse link
G Col7a1 collagen, type VII, alpha 1 multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of COL7A1 mRNA CTD PMID:33484791 NCBI chr 9:108,782,654...108,813,943
Ensembl chr 9:108,782,654...108,813,943
JBrowse link
G Cotl1 coactosin like F-actin binding protein 1 multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of COTL1 mRNA CTD PMID:25905778 NCBI chr 8:120,535,953...120,567,318
Ensembl chr 8:120,535,961...120,567,283
JBrowse link
G Cox17 cytochrome c oxidase assembly protein 17, copper chaperone affects expression EXP Streptozocin affects the expression of COX17 mRNA CTD PMID:18583417 NCBI chr16:38,167,332...38,173,125
Ensembl chr16:38,167,353...38,182,659
JBrowse link
G Cox5b cytochrome c oxidase subunit 5B multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of COX5B mRNA; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of COX5B mRNA] CTD PMID:37337224 NCBI chr 1:36,730,568...36,732,469
Ensembl chr 1:36,730,530...36,732,762
JBrowse link
G Cp ceruloplasmin multiple interactions
decreases expression
ISO caryophyllene inhibits the reaction [Streptozocin results in decreased expression of CP protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of CP protein] CTD PMID:26748309 NCBI chr 3:20,011,097...20,063,914
Ensembl chr 3:20,011,218...20,063,309
JBrowse link
G Cpeb2 cytoplasmic polyadenylation element binding protein 2 multiple interactions EXP [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of CPEB2 mRNA]; [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of CPEB2 protein] CTD PMID:38282657 NCBI chr 5:43,382,692...43,447,067
Ensembl chr 5:43,390,513...43,447,067
JBrowse link
G Cpeb4 cytoplasmic polyadenylation element binding protein 4 multiple interactions EXP [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of CPEB4 mRNA; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of CPEB4 protein CTD PMID:38282657 NCBI chr11:31,820,911...31,885,635
Ensembl chr11:31,822,211...31,885,634
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1a, liver increases expression
multiple interactions
ISO
EXP
Streptozocin results in increased expression of CPT1A mRNA
[resveratrol co-treated with Streptozocin] results in decreased expression of CPT1A mRNA; vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of CPT1A mRNA]
[Dietary Fats co-treated with Streptozocin] results in decreased expression of CPT1A mRNA; Acrylamide inhibits the reaction [Streptozocin results in increased expression of CPT1A mRNA]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of CPT1A mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of CPT1A protein]
CTD PMID:16684804 PMID:25905778 PMID:29988851 PMID:34896238 PMID:39047806 NCBI chr19:3,372,328...3,435,735
Ensembl chr19:3,372,334...3,435,733
JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 increases expression
multiple interactions
ISO Streptozocin results in increased expression of CPT2 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of CPT2 protein]
CTD PMID:21136691 NCBI chr 4:107,761,179...107,780,786
Ensembl chr 4:107,761,178...107,780,807
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions
decreases phosphorylation
ISO
EXP
[Streptozocin co-treated with Dietary Fats] results in decreased expression of CREB1 mRNA; Memantine inhibits the reaction [Streptozocin results in decreased phosphorylation of CREB1 protein]; xanthoceraside inhibits the reaction [Streptozocin results in decreased phosphorylation of CREB1 protein]
[Streptozocin co-treated with Dietary Fats] results in increased expression of CREB1 protein; CREB1 protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein]; HDAC3 protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CREB1 protein]; MIR10A mRNA affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CREB1 protein]
CTD PMID:20665664 PMID:23562514 PMID:27292126 NCBI chr 1:64,571,963...64,643,707
Ensembl chr 1:64,571,804...64,643,707
JBrowse link
G Crebbp CREB binding protein decreases expression ISO Streptozocin results in decreased expression of CREBBP mRNA CTD PMID:25905778 NCBI chr16:3,899,198...4,031,864
Ensembl chr16:3,899,192...4,031,861
JBrowse link
G Crot carnitine O-octanoyltransferase decreases expression
multiple interactions
ISO Streptozocin results in decreased expression of CROT mRNA
[resveratrol co-treated with Streptozocin] results in decreased expression of CROT mRNA
CTD PMID:25905778 NCBI chr 5:9,016,033...9,047,926
Ensembl chr 5:9,016,033...9,047,324
JBrowse link
G Crp C-reactive protein, pentraxin-related multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of CRP protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CRP protein] CTD PMID:33484791 NCBI chr 1:172,525,623...172,527,533
Ensembl chr 1:172,525,622...172,660,598
JBrowse link
G Cry1 cryptochrome circadian regulator 1 increases expression ISO Streptozocin results in increased expression of CRY1 mRNA CTD PMID:25905778 NCBI chr10:84,967,564...85,020,918
Ensembl chr10:84,967,564...85,020,928
JBrowse link
G Crybb3 crystallin, beta B3 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of CRYBB3 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CRYBB3 mRNA] CTD PMID:33484791 NCBI chr 5:113,223,705...113,230,102
Ensembl chr 5:113,223,705...113,229,450
JBrowse link
G Cryz crystallin, zeta decreases expression
multiple interactions
ISO Streptozocin results in decreased expression of CRYZ protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of CRYZ protein]
CTD PMID:19634143 NCBI chr 3:154,302,348...154,328,819
Ensembl chr 3:154,302,348...154,328,819
JBrowse link
G Csf1r colony stimulating factor 1 receptor multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of CSF1R mRNA CTD PMID:25905778 NCBI chr18:61,238,644...61,264,211
Ensembl chr18:61,233,670...61,265,221
JBrowse link
G Csn1s2a casein alpha s2-like A multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of CSN1S2A mRNA CTD PMID:33484791 NCBI chr 5:87,922,309...87,936,657
Ensembl chr 5:87,922,426...87,936,656
JBrowse link
G Csrp3 cysteine and glycine-rich protein 3 increases expression
multiple interactions
ISO Streptozocin results in increased expression of CSRP3 mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of CSRP3 mRNA]
CTD PMID:16684804 NCBI chr 7:48,480,146...48,497,799
Ensembl chr 7:48,480,146...48,497,781
JBrowse link
G Cst3 cystatin C multiple interactions
increases expression
ISO [Streptozocin co-treated with Fructose] results in increased expression of CST3 protein; Glyburide inhibits the reaction [Streptozocin results in increased expression of CST3 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of CST3 protein]; Tropisetron inhibits the reaction [Streptozocin results in increased expression of CST3 protein] CTD PMID:30551545 PMID:33387473 NCBI chr 2:148,713,642...148,717,432
Ensembl chr 2:148,713,642...148,717,612
JBrowse link
G Cstdc5 cystatin domain containing 5 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of CSTDC5 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CSTDC5 mRNA] CTD PMID:33484791 NCBI chr16:36,179,744...36,187,932
Ensembl chr16:36,179,744...36,188,110
JBrowse link
G Cth cystathionine gamma lyase multiple interactions EXP [Streptozocin co-treated with Dietary Fats] affects the expression of CTH mRNA CTD PMID:29127188 NCBI chr 3:157,599,885...157,630,718
Ensembl chr 3:157,599,885...157,630,714
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions
increases phosphorylation
EXP 5-Methoxypsoralen inhibits the reaction [Streptozocin results in increased phosphorylation of CTNNB1 protein]; Tadalafil inhibits the reaction [Streptozocin results in increased phosphorylation of CTNNB1 protein] CTD PMID:34428446 NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573
JBrowse link
G Ctsd cathepsin D increases expression EXP Streptozocin results in increased expression of CTSD protein CTD PMID:28468961 NCBI chr 7:141,929,647...141,941,564
Ensembl chr 7:141,929,648...141,941,775
JBrowse link
G Ctsk cathepsin K increases expression
multiple interactions
ISO
EXP
Streptozocin results in increased expression of CTSK mRNA; Streptozocin results in increased expression of CTSK protein
formononetin inhibits the reaction [Streptozocin results in increased expression of CTSK mRNA]; formononetin inhibits the reaction [Streptozocin results in increased expression of CTSK protein]
CTD PMID:25617479 PMID:35315182 NCBI chr 3:95,406,521...95,416,698
Ensembl chr 3:95,406,567...95,416,673
JBrowse link
G Ctss cathepsin S increases expression
multiple interactions
ISO Streptozocin results in increased expression of CTSS mRNA
[resveratrol co-treated with Streptozocin] results in increased expression of CTSS mRNA; vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of CTSS mRNA]
CTD PMID:16684804 PMID:25905778 NCBI chr 3:95,434,097...95,463,716
Ensembl chr 3:95,434,097...95,463,714
JBrowse link
G Cubn cubilin multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of CUBN protein; bicalutamide promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CUBN protein] CTD PMID:35151640 NCBI chr 2:13,281,149...13,496,687
Ensembl chr 2:13,281,149...13,496,624
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 multiple interactions ISO [Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in increased expression of CXCL1 protein]; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in increased expression of CXCL1 protein]] CTD PMID:36547818 NCBI chr 5:91,039,104...91,040,980
Ensembl chr 5:91,039,100...91,040,974
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 multiple interactions
decreases expression
EXP [Streptozocin co-treated with Oxygen deficiency] results in decreased expression of CXCL12 mRNA; CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of KLF15 protein]; CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CCN2 protein]; CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FN1 protein]; CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein]; KLF15 gene mutant form inhibits the reaction [CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CCN2 protein]]; KLF15 gene mutant form inhibits the reaction [CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FN1 protein]]; KLF15 gene mutant form inhibits the reaction [CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein]]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [[Streptozocin co-treated with Oxygen deficiency] results in decreased expression of CXCL12 mRNA]
Streptozocin results in decreased expression of CXCL12 mRNA; Streptozocin results in decreased expression of CXCL12 protein
CTD PMID:18227068 PMID:34310909 NCBI chr 6:117,145,496...117,158,329
Ensembl chr 6:117,145,496...117,158,328
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 multiple interactions ISO [Streptozocin co-treated with Tobacco Smoke Pollution] results in increased expression of CXCR4 protein CTD PMID:30421503 NCBI chr 1:128,515,936...128,520,036
Ensembl chr 1:128,515,936...128,520,030
JBrowse link
G Cyb561 cytochrome b-561 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of CYB561 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CYB561 mRNA] CTD PMID:33484791 NCBI chr11:105,824,528...105,844,157
Ensembl chr11:105,824,528...105,844,162
JBrowse link
G Cyba cytochrome b-245, alpha polypeptide multiple interactions
increases expression
ISO [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of CYBA mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in increased expression of CYBA protein; [Carbamazepine affects the susceptibility to [Dietary Fats co-treated with Streptozocin]] which results in decreased expression of CYBA mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of CYBA protein; [Resveratrol co-treated with Streptozocin] results in increased expression of CYBA mRNA; Bezafibrate inhibits the reaction [Streptozocin results in increased expression of CYBA mRNA]; candesartan inhibits the reaction [Streptozocin results in increased expression of CYBA mRNA] CTD PMID:12967931 PMID:16139267 PMID:25905778 PMID:35786680 NCBI chr 8:123,151,510...123,159,679
Ensembl chr 8:123,151,515...123,159,669
JBrowse link
G Cybb cytochrome b-245, beta polypeptide increases expression
multiple interactions
EXP
ISO
Streptozocin results in increased expression of CYBB mRNA; Streptozocin results in increased expression of CYBB protein
2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of NOX2 mRNA]; [fatostatin co-treated with Streptozocin] results in increased expression of CYBB mRNA; [Streptozocin co-treated with Niacinamide] results in increased expression of NOX2 mRNA; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of NOX2 mRNA]; Telmisartan inhibits the reaction [Streptozocin results in increased expression of CYBB protein]
[Streptozocin co-treated with Dietary Fats] results in increased expression of CYBB protein; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CYBB protein]
CTD PMID:19957251 PMID:21381899 PMID:29420703 PMID:35085591 PMID:37120126 NCBI chr  X:9,301,493...9,354,005
Ensembl chr  X:9,301,491...9,354,010
JBrowse link
G Cyc1 cytochrome c-1 increases expression
multiple interactions
ISO Streptozocin results in increased expression of CYC1 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of CYC1 protein]
CTD PMID:19634143 NCBI chr15:76,227,711...76,230,460
Ensembl chr15:76,227,723...76,230,460
JBrowse link
G Cycs cytochrome c, somatic affects localization
multiple interactions
increases expression
ISO
EXP
Streptozocin affects the localization of CYCS protein
arjunolic acid inhibits the reaction [Streptozocin affects the localization of CYCS protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of CYCS mRNA]; morin inhibits the reaction [Streptozocin results in increased expression of CYCS mRNA]; Phosphocreatine inhibits the reaction [Streptozocin results in increased expression of CYCS protein]; Thioctic Acid inhibits the reaction [Streptozocin affects the localization of CYCS protein]
Streptozocin results in increased expression of CYCS mRNA; Streptozocin results in increased expression of CYCS protein
Metformin inhibits the reaction [Streptozocin affects the localization of CYCS protein]; phillyrin inhibits the reaction [Streptozocin affects the localization of CYCS protein]
CTD PMID:19682444 PMID:19951573 PMID:34455488 PMID:34649470 PMID:35414346 More... NCBI chr 6:50,539,543...50,543,549
Ensembl chr 6:50,539,543...50,543,518
JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 increases expression ISO Streptozocin results in increased expression of CYP11B2 mRNA; Streptozocin results in increased expression of CYP11B2 protein CTD PMID:16043663 NCBI chr15:74,722,467...74,728,080
Ensembl chr15:74,722,467...74,728,167
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
EXP
ISO
Metformin promotes the reaction [Streptozocin results in increased expression of CYP1A1 mRNA]; Streptozocin promotes the reaction [Dietary Fats results in decreased expression of CYP1A1 mRNA]
[resveratrol co-treated with Streptozocin] results in increased expression of CYP1A1 mRNA
CTD PMID:22342832 PMID:25905778 PMID:29382564 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases expression
increases expression
multiple interactions
EXP
ISO
Streptozocin results in decreased expression of CYP1A2 protein
Streptozocin results in increased expression of CYP1A2 protein
[resveratrol co-treated with Streptozocin] results in decreased expression of CYP1A2 mRNA; [Streptozocin results in increased expression of CYP1A2 protein] which results in increased metabolism of Diazinon
Streptozocin results in decreased expression of CYP1A2 mRNA
[Streptozocin co-treated with Dietary Fats] results in decreased expression of CYP1A2 mRNA
CTD PMID:12700423 PMID:17442507 PMID:25905778 PMID:29127188 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986
JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of CYP26A1 mRNA CTD PMID:25905778 NCBI chr19:37,686,186...37,689,984
Ensembl chr19:37,686,246...37,689,984
JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of CYP26B1 mRNA CTD PMID:25905778 NCBI chr 6:84,548,396...84,570,890
Ensembl chr 6:84,548,396...84,570,890
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 multiple interactions EXP [Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP27A1 mRNA CTD PMID:29382564 NCBI chr 1:74,752,311...74,777,056
Ensembl chr 1:74,752,733...74,777,051
JBrowse link
G Cyp2a22 cytochrome P450, family 2, subfamily a, polypeptide 22 decreases expression
multiple interactions
ISO
EXP
Streptozocin results in decreased expression of CYP2A1 mRNA
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of CYP2A22 mRNA
CTD PMID:25905778 PMID:33484791 NCBI chr 7:26,631,564...26,638,838
Ensembl chr 7:26,631,056...26,638,809
JBrowse link
G Cyp2a4 cytochrome P450, family 2, subfamily a, polypeptide 4 multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of CYP2A4 mRNA CTD PMID:33484791 NCBI chr 7:26,006,617...26,014,513
Ensembl chr 7:26,006,594...26,014,513
JBrowse link
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 multiple interactions
increases expression
EXP Berberine inhibits the reaction [Streptozocin results in increased expression of CYP2B10 mRNA]; Streptozocin promotes the reaction [Dietary Fats results in decreased expression of CYP2B10 mRNA] CTD PMID:22342832 PMID:29382564 NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049
JBrowse link
G Cyp2b13 cytochrome P450, family 2, subfamily b, polypeptide 13 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of CYP2B13 mRNA CTD PMID:29127188 NCBI chr 7:25,760,813...25,795,622
Ensembl chr 7:25,760,922...25,795,622
JBrowse link
G Cyp2b9 cytochrome P450, family 2, subfamily b, polypeptide 9 multiple interactions
increases expression
EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of CYP2B9 mRNA; Berberine promotes the reaction [Streptozocin results in increased expression of CYP2B9 mRNA]; Metformin promotes the reaction [Streptozocin results in increased expression of CYP2B9 mRNA] CTD PMID:22342832 PMID:29127188 NCBI chr 7:25,872,775...25,910,086
Ensembl chr 7:25,872,836...25,910,086
JBrowse link
G Cyp2c39 cytochrome P450, family 2, subfamily c, polypeptide 39 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of CYP2C39 mRNA CTD PMID:29127188 NCBI chr19:39,335,790...39,558,012
Ensembl chr19:39,499,306...39,556,973
JBrowse link
G Cyp2c52-ps cytochrome P450, family 2, subfamily c, polypeptide 52, pseudogene multiple interactions ISO [Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP2C11 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP2C11 protein CTD PMID:24815820 NCBI chr19:38,965,106...38,992,071
Ensembl chr19:38,965,091...38,991,733
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases expression
increases expression
multiple interactions
EXP
ISO
Streptozocin results in decreased expression of CYP2E1 protein
Streptozocin results in increased expression of CYP2E1 mRNA; Streptozocin results in increased expression of CYP2E1 protein
[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased activity of CYP2E1 protein
CTD PMID:11752103 PMID:12700423 PMID:14693714 PMID:24815820 PMID:25905778 NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900
JBrowse link
G Cyp2j9 cytochrome P450, family 2, subfamily j, polypeptide 9 increases expression ISO Streptozocin results in increased expression of CYP2J4 mRNA CTD PMID:25905778 NCBI chr 4:96,456,661...96,480,748
Ensembl chr 4:96,456,666...96,479,815
JBrowse link
G Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 multiple interactions
increases expression
EXP [Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP3A11 mRNA; Berberine inhibits the reaction [Streptozocin results in increased expression of CYP3A11 mRNA] CTD PMID:22342832 PMID:29382564 NCBI chr 5:145,791,417...145,816,664
Ensembl chr 5:145,791,236...145,816,774
JBrowse link
G Cyp3a16 cytochrome P450, family 3, subfamily a, polypeptide 16 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of CYP3A16 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CYP3A16 mRNA] CTD PMID:33484791 NCBI chr 5:145,373,119...145,406,550
Ensembl chr 5:145,373,119...145,406,533
JBrowse link
G Cyp3a57 cytochrome P450, family 3, subfamily a, polypeptide 57 multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of CYP3A57 mRNA CTD PMID:33484791 NCBI chr 5:145,281,959...145,327,736
Ensembl chr 5:145,282,089...145,327,736
JBrowse link
G Cyp3a63-ps cytochrome P450, family 3, subfamily a, member 63, pseudogene multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of CYP3A63-PS mRNA CTD PMID:33484791 NCBI chr 5:145,560,905...145,584,717
Ensembl chr 5:145,560,902...145,570,803
JBrowse link
G Cyp4a10 cytochrome P450, family 4, subfamily a, polypeptide 10 increases expression
multiple interactions
EXP Streptozocin results in increased expression of CYP4A10 mRNA
Berberine inhibits the reaction [Streptozocin results in increased expression of CYP4A10 mRNA]
CTD PMID:22342832 NCBI chr 4:115,375,484...115,390,846
Ensembl chr 4:115,375,461...115,390,846
JBrowse link
G Cyp4a12b cytochrome P450, family 4, subfamily a, polypeptide 12B decreases expression
multiple interactions
ISO Streptozocin results in decreased expression of CYP4A1 mRNA
[Dietary Fats co-treated with Streptozocin] results in increased expression of CYP4A1 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of CYP4A1 protein; [resveratrol co-treated with Streptozocin] results in decreased expression of CYP4A1 mRNA
CTD PMID:24815820 PMID:25905778 NCBI chr 4:115,268,821...115,296,231
Ensembl chr 4:115,268,821...115,296,231
JBrowse link
G Cyp4a14 cytochrome P450, family 4, subfamily a, polypeptide 14 multiple interactions
increases expression
EXP Berberine inhibits the reaction [Streptozocin results in increased expression of CYP4A14 mRNA] CTD PMID:22342832 PMID:23319174 NCBI chr 4:115,343,397...115,353,355
Ensembl chr 4:115,343,397...115,353,339
JBrowse link
G Cyp4f14 cytochrome P450, family 4, subfamily f, polypeptide 14 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of CYP4F14 mRNA CTD PMID:29127188 NCBI chr17:33,122,331...33,136,353
Ensembl chr17:33,124,044...33,136,316
JBrowse link
G Cyp7a1 cytochrome P450, family 7, subfamily a, polypeptide 1 increases expression
multiple interactions
ISO
EXP
Streptozocin results in increased expression of CYP7A1 mRNA
[Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 protein; Acrylamide inhibits the reaction [Streptozocin results in increased expression of CYP7A1 mRNA]
[Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 protein; Fungal Polysaccharides inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 mRNA]; Fungal Polysaccharides inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 protein]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 mRNA]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 protein]
CTD PMID:10393316 PMID:29382564 PMID:31100278 PMID:34896238 NCBI chr 4:6,265,612...6,275,632
Ensembl chr 4:6,265,612...6,275,633
JBrowse link
G Cyp7b1 cytochrome P450, family 7, subfamily b, polypeptide 1 multiple interactions EXP [Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7B1 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of CYP7B1 mRNA CTD PMID:29127188 PMID:29382564 NCBI chr 3:18,126,108...18,298,054
Ensembl chr 3:18,126,114...18,297,502
JBrowse link
G Cyp8b1 cytochrome P450, family 8, subfamily b, polypeptide 1 multiple interactions
increases expression
ISO
EXP
[resveratrol co-treated with Streptozocin] results in decreased expression of CYP8B1 mRNA; INS1 protein inhibits the reaction [Streptozocin results in increased expression of CYP8B1 mRNA]; Streptozocin inhibits the reaction [resveratrol results in increased expression of CYP8B1 mRNA]
Streptozocin results in increased expression of CYP8B1 mRNA; Streptozocin results in increased expression of CYP8B1 protein
[Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP8B1 mRNA
CTD PMID:10393316 PMID:25905778 PMID:29382564 NCBI chr 9:121,743,422...121,745,371
Ensembl chr 9:121,743,422...121,745,371
JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 increases expression
multiple interactions
EXP Streptozocin results in increased expression of CYSLTR1 mRNA; Streptozocin results in increased expression of CYSLTR1 protein
montelukast inhibits the reaction [Streptozocin results in increased expression of CYSLTR1 mRNA]; montelukast inhibits the reaction [Streptozocin results in increased expression of CYSLTR1 protein]
CTD PMID:27702591 NCBI chr  X:105,617,952...105,647,329
Ensembl chr  X:105,617,952...105,647,285
JBrowse link
G Cyyr1 cysteine and tyrosine-rich protein 1 multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of CYYR1 mRNA CTD PMID:25905778 NCBI chr16:85,247,245...85,347,793
Ensembl chr16:85,218,421...85,350,285
JBrowse link
G Dao D-amino acid oxidase increases expression
multiple interactions
ISO Streptozocin results in increased expression of DAO protein
Trientine inhibits the reaction [Streptozocin results in increased expression of DAO protein]
CTD PMID:19634143 NCBI chr 5:114,137,696...114,163,736
Ensembl chr 5:114,141,764...114,163,743
JBrowse link
G Dapk1 death associated protein kinase 1 decreases expression ISO Streptozocin results in decreased expression of DAPK1 mRNA CTD PMID:25905778 NCBI chr13:60,749,506...60,911,005
Ensembl chr13:60,749,761...60,911,005
JBrowse link
G Dapl1 death associated protein-like 1 multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of DAPL1 mRNA CTD PMID:33484791 NCBI chr 2:59,314,997...59,335,364
Ensembl chr 2:59,314,997...59,335,364
JBrowse link
G Dbn1 drebrin 1 decreases expression ISO Streptozocin results in decreased expression of DBN1 protein CTD PMID:23333261 NCBI chr13:55,621,241...55,635,874
Ensembl chr13:55,621,242...55,635,924
JBrowse link
G Dbt dihydrolipoamide branched chain transacylase E2 affects expression EXP Streptozocin affects the expression of DBT mRNA CTD PMID:18583417 NCBI chr 3:116,306,776...116,343,630
Ensembl chr 3:116,306,719...116,343,630
JBrowse link
G Dcc DCC netrin 1 receptor multiple interactions
increases expression
EXP NTN1 protein promotes the reaction [Streptozocin results in increased expression of DCC mRNA]; NTN1 protein promotes the reaction [Streptozocin results in increased expression of DCC protein]
Streptozocin results in increased expression of DCC mRNA; Streptozocin results in increased expression of DCC protein
CTD PMID:29059224 NCBI chr18:71,386,703...72,484,299
Ensembl chr18:71,386,705...72,484,140
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions
increases expression
EXP
ISO
Streptozocin results in increased expression of DDIT3; Streptozocin results in increased expression of DDIT3 mRNA; Streptozocin results in increased expression of DDIT3 protein
[Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of DDIT3 mRNA]; [Streptozocin co-treated with bisphenol A] results in increased expression of DDIT3 protein; [Streptozocin co-treated with Ethinyl Estradiol] results in increased expression of DDIT3 mRNA; [Streptozocin co-treated with Ethinyl Estradiol] results in increased expression of DDIT3 protein; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of DDIT3 mRNA; [Streptozocin co-treated with octylphenol] results in increased expression of DDIT3 mRNA; [Streptozocin co-treated with octylphenol] results in increased expression of DDIT3 protein; FGF21 protein affects the reaction [Streptozocin results in increased expression of DDIT3]; Streptozocin promotes the reaction [bisphenol A results in increased expression of DDIT3 mRNA]; sulforaphane inhibits the reaction [Streptozocin results in increased expression of DDIT3 protein]
4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of DDIT3 protein]; [Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of DDIT3 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of DDIT3 mRNA; Bilirubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of DDIT3 mRNA]; Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of DDIT3 protein]; Vitamin B 12 inhibits the reaction [Streptozocin results in increased expression of DDIT3 protein]
streptozocin increases expression of Ddit3 protein in heart
CTD
RGD
PMID:23499715 PMID:24967692 PMID:29935216 PMID:30980806 PMID:34801538 More... RGD:156430337 NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157
Ensembl chr10:127,126,643...127,132,157
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of DDIT4 mRNA CTD PMID:25905778 NCBI chr10:59,785,497...59,787,592
Ensembl chr10:59,785,491...59,787,656
JBrowse link
G Decr1 2,4-dienoyl CoA reductase 1, mitochondrial increases expression
multiple interactions
ISO Streptozocin results in increased expression of DECR1 mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of DECR1 mRNA]
CTD PMID:16684804 NCBI chr 4:15,917,240...15,945,377
Ensembl chr 4:15,917,240...15,945,507
JBrowse link
G Derl1 Der1-like domain family, member 1 multiple interactions
increases expression
ISO 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of DERL1 protein] CTD PMID:30980806 NCBI chr15:57,732,898...57,755,814
Ensembl chr15:57,732,898...57,755,844
JBrowse link
G Derl3 Der1-like domain family, member 3 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of DERL3 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of DERL3 mRNA] CTD PMID:33484791 NCBI chr10:75,729,232...75,731,775
Ensembl chr10:75,729,247...75,731,775
JBrowse link
G Des desmin multiple interactions
increases expression
ISO Mycophenolic Acid inhibits the reaction [Streptozocin results in increased expression of DES protein]; Valsartan inhibits the reaction [Streptozocin results in increased expression of DES protein] CTD PMID:12197670 PMID:17624267 NCBI chr 1:75,336,936...75,345,223
Ensembl chr 1:75,336,973...75,345,223
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 multiple interactions EXP [Dietary Fats co-treated with Streptozocin] results in increased expression of DGAT1 mRNA; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of DGAT1 mRNA] CTD PMID:33812996 NCBI chr15:76,386,215...76,396,167
Ensembl chr15:76,386,215...76,396,153
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 multiple interactions ISO [[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in decreased expression of DGAT2 mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of DGAT2 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of DGAT2 mRNA CTD PMID:35786680 NCBI chr 7:98,802,870...98,831,920
Ensembl chr 7:98,802,865...98,831,926
JBrowse link
G Dgkh diacylglycerol kinase, eta multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of DGKH mRNA CTD PMID:20665664 NCBI chr14:78,796,789...78,970,169
Ensembl chr14:78,796,190...78,970,216
JBrowse link
G Dhrs7 dehydrogenase/reductase 7 multiple interactions ISO [resveratrol co-treated with Streptozocin] results in decreased expression of DHRS7 mRNA CTD PMID:25905778 NCBI chr12:72,697,127...72,711,678
Ensembl chr12:72,697,127...72,711,683
JBrowse link
G Dhrs9 dehydrogenase/reductase 9 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of DHRS9 mRNA CTD PMID:29127188 NCBI chr 2:69,210,806...69,233,430
Ensembl chr 2:69,210,789...69,234,877
JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein multiple interactions EXP [Streptozocin co-treated with NQO1 protein mutant form] results in increased secretion of DIABLO protein CTD PMID:23458895 NCBI chr 5:123,649,393...123,664,825
Ensembl chr 5:123,647,828...123,662,239
JBrowse link
G Dio1 deiodinase, iodothyronine, type I multiple interactions ISO [resveratrol co-treated with Streptozocin] results in decreased expression of DIO1 mRNA CTD PMID:25905778 NCBI chr 4:107,148,662...107,164,365
Ensembl chr 4:107,148,662...107,164,366
JBrowse link
G Dio3 deiodinase, iodothyronine type III multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of DIO3 mRNA CTD PMID:33484791 NCBI chr12:110,245,664...110,247,531
Ensembl chr12:110,245,502...110,247,531
JBrowse link
G Dlat dihydrolipoamide S-acetyltransferase multiple interactions
increases expression
ISO Trientine inhibits the reaction [Streptozocin results in increased expression of DLAT protein] CTD PMID:21136691 NCBI chr 9:50,545,933...50,571,080
Ensembl chr 9:50,545,933...50,571,080
JBrowse link
G Dld dihydrolipoamide dehydrogenase increases expression
multiple interactions
ISO Streptozocin results in increased expression of DLD protein
Trientine inhibits the reaction [Streptozocin results in increased expression of DLD protein]
CTD PMID:21136691 NCBI chr12:31,381,561...31,401,470
Ensembl chr12:31,381,276...31,401,452
JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 multiple interactions
decreases expression
ISO Ibuprofen inhibits the reaction [Streptozocin results in decreased expression of DLG4 protein]; Memantine inhibits the reaction [Streptozocin results in decreased expression of DLG4 protein] CTD PMID:24333387 NCBI chr11:69,908,029...69,938,107
Ensembl chr11:69,907,768...69,938,348
JBrowse link
G Dlgap2 DLG associated protein 2 multiple interactions
decreases expression
ISO Ibuprofen inhibits the reaction [Streptozocin results in decreased expression of DLGAP2 mRNA]; Memantine inhibits the reaction [Streptozocin results in decreased expression of DLGAP2 mRNA] CTD PMID:24333387 NCBI chr 8:14,145,793...14,903,426
Ensembl chr 8:14,145,865...14,897,680
JBrowse link
G Dlst dihydrolipoamide S-succinyltransferase multiple interactions
increases expression
ISO Trientine inhibits the reaction [Streptozocin results in increased expression of DLST protein] CTD PMID:19634143 PMID:21136691 NCBI chr12:85,157,597...85,180,865
Ensembl chr12:85,157,607...85,181,619
JBrowse link
G Dmbt1 deleted in malignant brain tumors 1 multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of DMBT1 mRNA CTD PMID:25905778 NCBI chr 7:130,633,787...130,723,357
Ensembl chr 7:130,633,776...130,723,357
JBrowse link
G Dnah5 dynein, axonemal, heavy chain 5 multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of DNAH5 mRNA CTD PMID:33484791 NCBI chr15:28,155,000...28,472,191
Ensembl chr15:28,203,898...28,472,198
JBrowse link
G Dnm1l dynamin 1-like increases expression
multiple interactions
ISO
EXP
Streptozocin results in increased expression of DNM1L protein
ferulic acid inhibits the reaction [Streptozocin results in increased expression of DNM1L protein]
[Dietary Fats co-treated with Streptozocin] results in increased expression of DNM1L mRNA
CTD PMID:31029786 PMID:33812996 NCBI chr16:16,130,092...16,176,863
Ensembl chr16:16,130,094...16,176,823
JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions
decreases expression
EXP
ISO
[Streptozocin co-treated with Dietary Fats] results in increased expression of DNMT1 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of DNMT1 protein; Folic Acid deficiency promotes the reaction [Streptozocin results in decreased expression of DNMT1 mRNA]; Folic Acid inhibits the reaction [Streptozocin results in decreased expression of DNMT1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in decreased expression of DNMT1 mRNA]
[Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in decreased expression of DNMT1 mRNA]; [Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in decreased expression of DNMT1 protein]; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in decreased expression of DNMT1 mRNA]]; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in decreased expression of DNMT1 protein]]
CTD PMID:28422052 PMID:29127188 PMID:36547818 NCBI chr 9:20,818,501...20,871,084
Ensembl chr 9:20,818,505...20,871,184
JBrowse link
G Dnmt3a DNA methyltransferase 3A multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of DNMT3A mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of DNMT3A protein CTD PMID:29127188 NCBI chr12:3,851,559...3,964,442
Ensembl chr12:3,856,007...3,964,443
JBrowse link
G Dnmt3b DNA methyltransferase 3B multiple interactions
increases expression
EXP
ISO
[Streptozocin co-treated with Dietary Fats] results in increased expression of DNMT3B mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of DNMT3B protein
Streptozocin results in increased expression of DNMT3B mRNA
CTD PMID:29127188 PMID:37081038 NCBI chr 2:153,491,332...153,529,650
Ensembl chr 2:153,491,370...153,529,650
JBrowse link
G Dpp4 dipeptidylpeptidase 4 increases response to substance
decreases activity
decreases expression
increases expression
ISO DPP4 results in increased susceptibility to Streptozocin
Streptozocin results in decreased activity of DPP4 protein
Streptozocin results in decreased expression of DPP4 protein
Streptozocin results in increased expression of DPP4 mRNA
CTD PMID:16045816 PMID:18931022 NCBI chr 2:62,160,417...62,242,635
Ensembl chr 2:62,160,417...62,242,575
JBrowse link
G Drd1 dopamine receptor D1 increases phosphorylation
multiple interactions
ISO Streptozocin results in increased phosphorylation of DRD1 protein
tempol inhibits the reaction [Streptozocin results in increased phosphorylation of DRD1 protein]
CTD PMID:16478977 NCBI chr13:54,205,202...54,209,677
Ensembl chr13:54,205,202...54,209,724
JBrowse link
G Ece1 endothelin converting enzyme 1 multiple interactions
increases expression
ISO Triterpenes inhibits the reaction [Streptozocin results in increased expression of ECE1 mRNA] CTD PMID:19000375 NCBI chr 4:137,589,548...137,692,540
Ensembl chr 4:137,589,548...137,692,540
JBrowse link
G Echs1 enoyl Coenzyme A hydratase, short chain, 1, mitochondrial increases expression ISO Streptozocin results in increased expression of ECHS1 protein CTD PMID:21136691 NCBI chr 7:139,685,623...139,696,334
Ensembl chr 7:139,685,623...139,696,389
JBrowse link
G Edaradd EDAR associated via death domain multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of EDARADD mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of EDARADD mRNA] CTD PMID:33484791 NCBI chr13:12,486,090...12,535,413
Ensembl chr13:12,487,513...12,535,319
JBrowse link
G Edem1 ER degradation enhancer, mannosidase alpha-like 1 increases expression ISO Streptozocin results in increased expression of EDEM1 mRNA CTD PMID:25905778 NCBI chr 6:108,800,984...108,836,317
Ensembl chr 6:108,805,602...108,836,317
JBrowse link
G Edem3 ER degradation enhancer, mannosidase alpha-like 3 multiple interactions EXP [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of EDEM3 mRNA]; [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of EDEM3 protein]; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of EDEM3 mRNA; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of EDEM3 protein CTD PMID:38282657 NCBI chr 1:151,631,099...151,698,079
Ensembl chr 1:151,631,122...151,697,802
JBrowse link
G Edn1 endothelin 1 increases expression
multiple interactions
ISO Streptozocin results in increased expression of EDN1 mRNA; Streptozocin results in increased expression of EDN1 protein
Bezafibrate inhibits the reaction [Streptozocin results in increased expression of EDN1 mRNA]; Triterpenes inhibits the reaction [Streptozocin results in increased expression of EDN1 protein]
diphenyleneiodonium inhibits the reaction [Streptozocin promotes the reaction [EDN1 protein results in increased chemical synthesis of Inositol 1,4,5-Trisphosphate]]; Streptozocin promotes the reaction [EDN1 protein results in increased chemical synthesis of Inositol 1,4,5-Trisphosphate]
CTD PMID:12458661 PMID:12967931 PMID:19000375 PMID:20691780 NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466
JBrowse link
G Efna3 ephrin A3 multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of EFNA3 mRNA CTD PMID:33484791 NCBI chr 3:89,221,200...89,231,359
Ensembl chr 3:89,221,206...89,230,272
JBrowse link
G Efnb2 ephrin B2 affects expression EXP Streptozocin affects the expression of EFNB2 mRNA CTD PMID:26073000 NCBI chr 8:8,667,235...8,711,242
Ensembl chr 8:8,667,434...8,711,242
JBrowse link
G Egfr epidermal growth factor receptor increases expression ISO Streptozocin results in increased expression of EGFR mRNA CTD PMID:37081038 NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158
JBrowse link
G Ehhadh enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase increases expression ISO Streptozocin results in increased expression of EHHADH mRNA CTD PMID:25905778 NCBI chr16:21,580,035...21,606,589
Ensembl chr16:21,580,037...21,606,557
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions
increases phosphorylation
EXP
ISO
[Dietary Fats co-treated with Streptozocin] results in increased expression of EIF2AK3 protein; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of EIF2AK3 protein]
[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of EIF2AK3 protein; Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of EIF2AK3 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of EIF2AK3 protein]; Vitamin B 12 inhibits the reaction [Streptozocin results in increased phosphorylation of EIF2AK3 protein]
streptozocin increases phosphorylation of Eif2ak3 protein in heart
CTD
RGD
PMID:33812996 PMID:34801538 PMID:38049026 PMID:36044268 RGD:156430337 NCBI chr 6:70,821,468...70,882,225
Ensembl chr 6:70,821,499...70,882,229
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2, subunit 1 alpha multiple interactions EXP [Dietary Fats co-treated with Streptozocin] results in increased phosphorylation of EIF2S1 protein; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased phosphorylation of EIF2S1 protein] CTD PMID:33812996 NCBI chr12:78,908,846...78,933,784
Ensembl chr12:78,908,593...78,933,784
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions
increases expression
ISO vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of EIF4EBP1 mRNA] CTD PMID:16684804 NCBI chr 8:27,750,355...27,765,684
Ensembl chr 8:27,750,357...27,766,702
JBrowse link
G Elk1 ELK1, member of ETS oncogene family increases phosphorylation ISO Streptozocin results in increased phosphorylation of ELK1 protein CTD PMID:12642375 NCBI chr  X:20,799,634...20,816,847
Ensembl chr  X:20,799,634...20,816,847
JBrowse link
G Elovl7 ELOVL fatty acid elongase 7 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of ELOVL7 mRNA CTD PMID:29127188 NCBI chr13:108,350,860...108,423,643
Ensembl chr13:108,350,938...108,422,217
JBrowse link
G Eno1 enolase 1, alpha non-neuron increases expression ISO Streptozocin results in increased expression of ENO1 protein CTD PMID:24924950 NCBI chr 4:150,321,165...150,333,336
Ensembl chr 4:150,321,178...150,333,336
Ensembl chr18:150,321,178...150,333,336
JBrowse link
G Eno2 enolase 2, gamma neuronal multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of ENO2 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ENO2 mRNA] CTD PMID:33484791 NCBI chr 6:124,737,018...124,746,489
Ensembl chr 6:124,737,016...124,746,636
JBrowse link
G Enpep glutamyl aminopeptidase multiple interactions
increases activity
ISO
EXP
[resveratrol co-treated with Streptozocin] results in decreased expression of ENPEP mRNA
Streptozocin results in increased activity of ENPEP protein
CTD PMID:25905778 PMID:28468961 NCBI chr 3:129,062,826...129,126,398
Ensembl chr 3:129,062,824...129,126,369
JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 multiple interactions ISO [resveratrol co-treated with Streptozocin] results in decreased expression of ENPP2 mRNA CTD PMID:25905778 NCBI chr15:54,702,297...54,816,284
Ensembl chr15:54,702,297...54,816,288
JBrowse link
G Ep300 E1A binding protein p300 increases expression
multiple interactions
ISO Streptozocin results in increased expression of EP300 mRNA
3-aminobenzamide inhibits the reaction [Streptozocin results in increased expression of EP300 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of EP300 mRNA]
CTD PMID:22228707 NCBI chr15:81,470,329...81,536,273
Ensembl chr15:81,469,552...81,536,278
JBrowse link
G Epcam epithelial cell adhesion molecule multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of EPCAM mRNA CTD PMID:25905778 NCBI chr17:87,943,407...87,958,555
Ensembl chr17:87,943,407...87,958,557
JBrowse link
G Ephx1 epoxide hydrolase 1, microsomal increases expression
multiple interactions
ISO Streptozocin results in increased expression of EPHX1 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of EPHX1 protein]
CTD PMID:19634143 NCBI chr 1:180,817,121...180,845,134
Ensembl chr 1:180,803,775...180,848,469
JBrowse link
G Ephx2 epoxide hydrolase 2, cytoplasmic increases expression
multiple interactions
decreases response to substance
ISO
EXP
Streptozocin results in increased expression of EPHX2 protein
EPHX2 gene mutant form inhibits the reaction [Streptozocin results in increased activity of RELA protein]; EPHX2 gene mutant form inhibits the reaction [Streptozocin results in increased secretion of CCL2 protein]
EPHX2 gene mutant form results in decreased susceptibility to Streptozocin
CTD PMID:21832210 PMID:23611540 NCBI chr14:66,321,821...66,361,971
Ensembl chr14:66,321,823...66,361,949
JBrowse link
G Epo erythropoietin multiple interactions
decreases expression
increases expression
ISO [Dietary Fats co-treated with Streptozocin] results in decreased expression of EPO protein; dapagliflozin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of EPO protein]; Enalapril inhibits the reaction [Streptozocin results in increased expression of EPO mRNA]; Simvastatin inhibits the reaction [Streptozocin results in decreased expression of EPO protein]; Simvastatin inhibits the reaction [Streptozocin results in increased expression of EPO mRNA] CTD PMID:19958114 PMID:20821229 PMID:34391751 NCBI chr 5:137,481,282...137,484,078
Ensembl chr 5:137,481,282...137,531,504
JBrowse link
G Epor erythropoietin receptor multiple interactions
decreases expression
increases expression
ISO Enalapril inhibits the reaction [Streptozocin results in increased expression of EPOR mRNA]; Enalapril inhibits the reaction [Streptozocin results in increased expression of EPOR protein]; Simvastatin inhibits the reaction [Streptozocin results in decreased expression of EPOR protein]; Simvastatin inhibits the reaction [Streptozocin results in increased expression of EPOR mRNA]
Streptozocin results in increased expression of EPOR mRNA; Streptozocin results in increased expression of EPOR protein
CTD PMID:19958114 PMID:20821229 NCBI chr 9:21,870,193...21,874,915
Ensembl chr 9:21,870,193...21,874,802
JBrowse link
G Ercc1 excision repair cross-complementing rodent repair deficiency, complementation group 1 increases expression
multiple interactions
ISO Streptozocin results in increased expression of ERCC1 mRNA; Streptozocin results in increased expression of ERCC1 protein
3-aminobenzamide inhibits the reaction [Streptozocin results in increased expression of ERCC1 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of ERCC1 mRNA]
CTD PMID:22228707 NCBI chr 7:19,079,016...19,090,449
Ensembl chr 7:19,078,703...19,090,449
JBrowse link
G Ercc4 excision repair cross-complementing rodent repair deficiency, complementation group 4 multiple interactions
increases expression
ISO 3-aminobenzamide inhibits the reaction [Streptozocin results in increased expression of ERCC4 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of ERCC4 mRNA]
Streptozocin results in increased expression of ERCC4 mRNA; Streptozocin results in increased expression of ERCC4 protein
CTD PMID:22228707 NCBI chr16:12,927,600...12,969,873
Ensembl chr16:12,927,548...12,968,481
JBrowse link
G Ermap erythroblast membrane-associated protein multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of ERMAP mRNA CTD PMID:33484791 NCBI chr 4:119,032,654...119,047,210
Ensembl chr 4:119,032,654...119,047,208
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signalling 1 multiple interactions
increases expression
ISO
EXP
4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of ERN1 protein modified form]; [Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of ERN1 protein; Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of ERN1 protein]
[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of ERN1 protein; aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of ERN1 protein]
CTD PMID:20399799 PMID:34801538 PMID:35961541 NCBI chr11:106,285,474...106,378,701
Ensembl chr11:106,285,476...106,378,678
JBrowse link
G Ern2 endoplasmic reticulum to nucleus signalling 2 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of ERN2 protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ERN2 protein] CTD PMID:33484791 NCBI chr 7:121,769,116...121,785,454
Ensembl chr 7:121,769,116...121,785,430
JBrowse link
G Esr1 estrogen receptor 1 (alpha) multiple interactions
decreases expression
increases expression
EXP
ISO
bisphenol A inhibits the reaction [Streptozocin results in decreased expression of ESR1 mRNA]; Ethinyl Estradiol inhibits the reaction [Streptozocin results in decreased expression of ESR1 mRNA]; octylphenol inhibits the reaction [Streptozocin results in decreased expression of ESR1 mRNA]
[Streptozocin co-treated with Tobacco Smoke Pollution] results in increased expression of ESR1 protein
Streptozocin results in increased expression of ESR1
CTD PMID:24781736 PMID:30421503 PMID:32469605 NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614
JBrowse link
G Esr2 estrogen receptor 2 (beta) multiple interactions
decreases expression
EXP bisphenol A inhibits the reaction [Streptozocin results in decreased expression of ESR2 mRNA]; bisphenol A inhibits the reaction [Streptozocin results in decreased expression of ESR2 protein]; ESR2 protein affects the reaction [Raloxifene Hydrochloride inhibits the reaction [Streptozocin results in decreased secretion of MMP2 protein]]; Ethinyl Estradiol inhibits the reaction [Streptozocin results in decreased expression of ESR2 mRNA]; octylphenol inhibits the reaction [Streptozocin results in decreased expression of ESR2 mRNA]
Streptozocin results in decreased expression of ESR2 mRNA; Streptozocin results in decreased expression of ESR2 protein
CTD PMID:23471663 PMID:24781736 PMID:35051763 NCBI chr12:76,167,193...76,224,033
Ensembl chr12:76,167,193...76,224,033
JBrowse link
G Etfa electron transferring flavoprotein, alpha polypeptide decreases expression
multiple interactions
ISO Streptozocin results in decreased expression of ETFA protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of ETFA protein]
CTD PMID:19634143 NCBI chr 9:55,361,720...55,419,528
Ensembl chr 9:55,361,792...55,419,527
JBrowse link
G Etfb electron transferring flavoprotein, beta polypeptide decreases expression
multiple interactions
ISO Streptozocin results in decreased expression of ETFB protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of ETFB protein]
CTD PMID:19634143 NCBI chr 7:43,093,496...43,107,224
Ensembl chr 7:43,093,507...43,107,224
JBrowse link
G Etfdh electron transferring flavoprotein, dehydrogenase affects expression EXP Streptozocin affects the expression of ETFDH mRNA CTD PMID:18583417 NCBI chr 3:79,511,095...79,536,074
Ensembl chr 3:79,511,095...79,536,807
JBrowse link
G Ets1 E26 avian leukemia oncogene 1, 5' domain multiple interactions
decreases expression
ISO
EXP
SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of ETS1 mRNA] CTD PMID:27629361 NCBI chr 9:32,547,501...32,669,116
Ensembl chr 9:32,547,517...32,669,116
JBrowse link
G Eya2 EYA transcriptional coactivator and phosphatase 2 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of EYA2 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of EYA2 mRNA] CTD PMID:33484791 NCBI chr 2:165,436,892...165,613,645
Ensembl chr 2:165,436,952...165,613,647
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of EZH2 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of EZH2 protein CTD PMID:29127188 NCBI chr 6:47,507,208...47,613,843
Ensembl chr 6:47,507,073...47,572,275
JBrowse link
G F3 coagulation factor III, tissue factor decreases activity ISO Streptozocin results in decreased activity of F3 protein CTD PMID:32864810 NCBI chr 3:121,517,186...121,528,701
Ensembl chr 3:121,517,186...121,528,697
JBrowse link
G Fabp4 fatty acid binding protein 4, adipocyte multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of FABP4 mRNA CTD PMID:29127188 NCBI chr 3:10,269,406...10,273,653
Ensembl chr 3:10,269,148...10,273,636
JBrowse link
G Fabp7 fatty acid binding protein 7, brain multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of FABP7 mRNA CTD PMID:29127188 NCBI chr10:57,661,019...57,664,546
Ensembl chr10:57,660,977...57,664,546
JBrowse link
G Fadd Fas associated via death domain increases expression
multiple interactions
ISO Streptozocin results in increased expression of FADD protein
Anthocyanins inhibits the reaction [Streptozocin results in increased expression of FADD protein]
CTD PMID:28856781 NCBI chr 7:144,132,060...144,136,178
Ensembl chr 7:144,131,055...144,136,200
JBrowse link
G Fads1 fatty acid desaturase 1 decreases expression ISO Streptozocin results in decreased expression of FADS1 mRNA CTD PMID:25246140 NCBI chr19:10,160,245...10,174,238
Ensembl chr19:10,160,252...10,174,241
JBrowse link
G Fam184a family with sequence similarity 184, member A multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of FAM184A mRNA CTD PMID:33484791 NCBI chr10:53,509,131...53,627,368
Ensembl chr10:53,509,241...53,627,219
JBrowse link
G Fars2 phenylalanine-tRNA synthetase 2, mitochondrial affects expression EXP Streptozocin affects the expression of FARS2 mRNA CTD PMID:18583417 NCBI chr13:36,301,373...36,721,569
Ensembl chr13:36,301,395...36,910,254
JBrowse link
G Fas Fas cell surface death receptor multiple interactions
increases expression
ISO Anthocyanins inhibits the reaction [Streptozocin results in increased expression of FAS protein] CTD PMID:28856781 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
JBrowse link
G Fasl Fas ligand multiple interactions
increases expression
ISO Anthocyanins inhibits the reaction [Streptozocin results in increased expression of FASLG protein]; rosiglitazone inhibits the reaction [Streptozocin results in increased expression of FASLG mRNA]
Streptozocin results in increased expression of FASLG mRNA; Streptozocin results in increased expression of FASLG protein
CTD PMID:21791967 PMID:28856781 NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064
JBrowse link
G Fasn fatty acid synthase decreases expression
multiple interactions
increases expression
ISO
EXP
Streptozocin results in decreased expression of FASN mRNA
Allopurinol inhibits the reaction [Streptozocin results in increased expression of FASN mRNA]; Allopurinol inhibits the reaction [Streptozocin results in increased expression of FASN protein]; GHRL protein promotes the reaction [Streptozocin results in decreased expression of FASN mRNA]; INS protein inhibits the reaction [Streptozocin results in decreased expression of FASN mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of FASN mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of FASN protein]
Streptozocin results in increased expression of FASN mRNA; Streptozocin results in increased expression of FASN protein
[Dietary Fats co-treated with Streptozocin] results in decreased expression of FASN mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of FASN mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of FASN mRNA; Acrylamide inhibits the reaction [Streptozocin results in increased expression of FASN mRNA]; esculetin promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of FASN mRNA]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FASN mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FASN mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of FASN mRNA]
CTD PMID:20219977 PMID:23647015 PMID:27769711 PMID:29988851 PMID:33812996 More... NCBI chr11:120,696,784...120,715,992
Ensembl chr11:120,696,672...120,715,373
JBrowse link
G Faxc failed axon connections homolog multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of FAXC mRNA CTD PMID:33484791 NCBI chr 4:21,930,906...22,001,461
Ensembl chr 4:21,931,329...21,996,839
JBrowse link
G Fbp1 fructose bisphosphatase 1 increases activity
multiple interactions
ISO Streptozocin results in increased activity of FBP1 protein
citronellol inhibits the reaction [Streptozocin results in increased activity of FBP1 protein]
CTD PMID:26944432 NCBI chr13:63,012,567...63,036,112
Ensembl chr13:63,012,567...63,036,096
JBrowse link
G Fbp2 fructose bisphosphatase 2 multiple interactions EXP [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FBP2 protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of FBP2 protein CTD PMID:25446853 NCBI chr13:62,984,698...63,006,214
Ensembl chr13:62,984,691...63,006,236
JBrowse link
G Fbxo32 F-box protein 32 multiple interactions
increases expression
ISO
EXP
4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of FBXO32 protein] CTD PMID:30635400 PMID:30980806 NCBI chr15:58,039,275...58,078,288
Ensembl chr15:58,039,275...58,078,328
JBrowse link
G Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of FCER1G mRNA CTD PMID:25905778 NCBI chr 1:171,057,141...171,061,918
Ensembl chr 1:171,057,141...171,061,934
JBrowse link
G Fcgr3 Fc receptor, IgG, low affinity III increases expression
multiple interactions
ISO Streptozocin results in increased expression of FCGR3 mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of FCGR3 mRNA]
CTD PMID:16684804 NCBI chr 1:170,878,738...170,893,477
Ensembl chr 1:170,878,743...170,892,504
JBrowse link
G Fgf15 fibroblast growth factor 15 multiple interactions EXP [Dietary Fats co-treated with Streptozocin] results in increased expression of FGF15 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of FGF15 protein CTD PMID:29382564 NCBI chr 7:144,450,269...144,454,690
Ensembl chr 7:144,450,268...144,454,690
JBrowse link
G Fgf17 fibroblast growth factor 17 multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in increased expression of FGF17 mRNA; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in increased expression of FGF17 mRNA] CTD PMID:32303808 NCBI chr14:70,873,643...70,880,064
Ensembl chr14:70,873,643...70,879,708
JBrowse link
G Fgf21 fibroblast growth factor 21 multiple interactions
affects response to substance
EXP [Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of FGF21 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of FGF21 mRNA; FGF21 protein affects the reaction [Streptozocin results in increased expression of AIFM1]; FGF21 protein affects the reaction [Streptozocin results in increased expression of CASP12 protein modified form]; FGF21 protein affects the reaction [Streptozocin results in increased expression of DDIT3]; Glucagon analog promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of FGF21 protein]
FGF21 protein affects the susceptibility to Streptozocin
CTD PMID:23499715 PMID:29127188 PMID:29988851 NCBI chr 7:45,263,314...45,264,914
Ensembl chr 7:45,263,310...45,264,914
JBrowse link
G Fgfr1 fibroblast growth factor receptor 1 multiple interactions
decreases expression
ISO rosiglitazone inhibits the reaction [Streptozocin results in decreased expression of FGFR1] CTD PMID:24136780 NCBI chr 8:26,008,808...26,067,819
Ensembl chr 8:26,003,670...26,065,734
JBrowse link
G Fh1 fumarate hydratase 1 affects expression EXP Streptozocin affects the expression of FH1 mRNA CTD PMID:18583417 NCBI chr 1:175,428,944...175,453,201
Ensembl chr 1:175,427,940...175,453,201
JBrowse link
G Fis1 fission, mitochondrial 1 multiple interactions EXP [Dietary Fats co-treated with Streptozocin] results in increased expression of FIS1 mRNA CTD PMID:33812996 NCBI chr 5:136,982,129...136,995,088
Ensembl chr 5:136,982,129...136,995,088
JBrowse link
G Fitm2 fat storage-inducing transmembrane protein 2 multiple interactions ISO [resveratrol co-treated with Streptozocin] results in decreased expression of FITM2 mRNA CTD PMID:25905778 NCBI chr 2:163,310,623...163,314,549
Ensembl chr 2:163,308,299...163,314,549
JBrowse link
G Fkbp1b FK506 binding protein 1b multiple interactions
decreases expression
EXP
ISO
Streptozocin promotes the reaction [bisphenol A results in decreased expression of FKBP1B mRNA]; Streptozocin promotes the reaction [octylphenol results in decreased expression of FKBP1B mRNA]
Triterpenes inhibits the reaction [Streptozocin results in decreased expression of FKBP1B mRNA]; Triterpenes inhibits the reaction [Streptozocin results in decreased expression of FKBP1B protein]
Streptozocin results in decreased expression of FKBP1B mRNA; Streptozocin results in decreased expression of FKBP1B protein
CTD PMID:19000375 PMID:29935216 NCBI chr12:4,883,174...4,891,736
Ensembl chr12:4,883,174...4,891,591
JBrowse link
G Flacc1 flagellum associated containing coiled-coil domains 1 multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of FLACC1 mRNA CTD PMID:33484791 NCBI chr 1:58,696,085...58,735,167
Ensembl chr 1:58,686,062...58,735,148
JBrowse link
G Flt1 FMS-like tyrosine kinase 1 multiple interactions
increases expression
ISO
EXP
Simvastatin inhibits the reaction [Streptozocin results in increased expression of FLT1 mRNA]; Simvastatin inhibits the reaction [Streptozocin results in increased phosphorylation of and results in increased expression of FLT1 protein]; Streptozocin results in increased phosphorylation of and results in increased expression of FLT1 protein CTD PMID:20821229 PMID:26073000 NCBI chr 5:147,498,414...147,663,419
Ensembl chr 5:147,498,414...147,662,821
JBrowse link
G Fmo2 flavin containing monooxygenase 2 increases expression ISO Streptozocin results in increased expression of FMO2 mRNA CTD PMID:25905778 NCBI chr 1:162,701,886...162,726,327
Ensembl chr 1:162,701,886...162,726,295
JBrowse link
G Fmo4 flavin containing monooxygenase 4 multiple interactions ISO [resveratrol co-treated with Streptozocin] results in decreased expression of FMO4 mRNA CTD PMID:25905778 NCBI chr 1:162,620,757...162,643,788
Ensembl chr 1:162,620,757...162,641,541
JBrowse link
G Fn1 fibronectin 1 increases expression
multiple interactions
ISO
EXP
Streptozocin results in increased expression of FN1; Streptozocin results in increased expression of FN1 mRNA; Streptozocin results in increased expression of FN1 protein
3-aminobenzamide inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; [Streptozocin co-treated with Cadmium] results in increased expression of FN1 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein; Aspirin inhibits the reaction [Streptozocin results in increased expression of FN1]; benazepril inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; Carvedilol inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein]; esculetin inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; esculetin inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; fasudil inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; fenugreek seed meal inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; Gallic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of FN1 protein]; Organoselenium Compounds inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; stannous mesoporphyrin inhibits the reaction [4-(4-(3-adamantan-1-ylureido)cyclohexyloxy)benzoic acid inhibits the reaction [Streptozocin results in increased expression of FN1 protein]]; Trientine inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; XLF-III-43 inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; Zinc inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]
[AM6545 co-treated with Perindopril] inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; [Dietary Fats co-treated with Streptozocin] results in increased expression of FN1 protein; [fatostatin co-treated with Streptozocin] results in increased expression of FN1 mRNA; [fatostatin co-treated with Streptozocin] results in increased expression of FN1 protein; [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of FN1 protein]; [Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of FN1 protein; AM6545 inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; AM6545 inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; CREB1 protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein]; CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FN1 protein]; HDAC3 protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein]; KLF15 gene mutant form inhibits the reaction [CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FN1 protein]]; KLF15 gene mutant form promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FN1 protein]; Perindopril inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; Perindopril inhibits the reaction [Streptozocin results in increased expression of FN1 protein]
CTD PMID:11798618 PMID:12140129 PMID:14586741 PMID:16973718 PMID:19895808 More... NCBI chr 1:71,624,632...71,692,439
Ensembl chr 1:71,624,679...71,692,359
JBrowse link
G Fos FBJ osteosarcoma oncogene multiple interactions
increases expression
EXP formononetin inhibits the reaction [Streptozocin results in increased expression of FOS mRNA]; formononetin inhibits the reaction [Streptozocin results in increased expression of FOS protein]
Streptozocin results in increased expression of FOS mRNA; Streptozocin results in increased expression of FOS protein
CTD PMID:35315182 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
JBrowse link
G Fosb FBJ osteosarcoma oncogene B multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of FOSB mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of FOSB mRNA] CTD PMID:33484791 NCBI chr 7:19,036,621...19,043,970
Ensembl chr 7:19,036,621...19,043,976
JBrowse link
G Foxa2 forkhead box A2 multiple interactions ISO copper bis(3,5-diisopropylsalicylate) inhibits the reaction [Streptozocin results in decreased expression of FOXA2] CTD PMID:23795780 NCBI chr 2:147,884,797...147,888,889
Ensembl chr 2:147,884,797...147,888,889
JBrowse link
G Foxo1 forkhead box O1 multiple interactions
increases acetylation
decreases expression
decreases phosphorylation
EXP
ISO
[Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of FOXO1 protein; resveratrol inhibits the reaction [Streptozocin results in increased acetylation of FOXO1 protein]; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of FOXO1 protein]
[Dietary Fats co-treated with Streptozocin] affects the localization of FOXO1 protein; Butyric Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] affects the localization of FOXO1 protein]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] affects the localization of FOXO1 protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of FOXO1 mRNA]; Resveratrol inhibits the reaction [Streptozocin results in increased phosphorylation of and results in decreased activity of FOXO1 protein]; Streptozocin results in increased phosphorylation of and results in decreased activity of FOXO1 protein; Tribulus extract inhibits the reaction [Streptozocin results in decreased phosphorylation of FOXO1 protein]
CTD PMID:22733486 PMID:24889822 PMID:26522834 PMID:27270450 PMID:36627075 NCBI chr 3:52,175,758...52,257,530
Ensembl chr 3:52,175,757...52,260,642
JBrowse link
G Foxo3 forkhead box O3 decreases expression
increases expression
multiple interactions
ISO
EXP
Streptozocin results in decreased expression of FOXO3 protein
Streptozocin results in increased expression of FOXO3 protein modified form
Streptozocin results in increased expression of FOXO3 protein; Streptozocin results in increased expression of FOXO3 protein modified form
[Streptozocin co-treated with Resveratrol co-treated with Ramipril] results in increased phosphorylation of FOXO3 protein; [Streptozocin co-treated with Resveratrol] results in increased phosphorylation of FOXO3 protein; Resveratrol inhibits the reaction [Streptozocin results in increased expression of FOXO3 protein]
CTD PMID:17082237 PMID:18703049 PMID:23792339 PMID:31062909 NCBI chr10:42,057,841...42,152,691
Ensembl chr10:42,057,837...42,152,751
JBrowse link
G Fshb follicle stimulating hormone beta decreases expression
multiple interactions
ISO
EXP
Streptozocin results in decreased expression of FSHB protein
Sildenafil Citrate inhibits the reaction [Streptozocin results in decreased expression of FSHB protein]; vitexin inhibits the reaction [Streptozocin results in decreased expression of FSHB protein]
[Streptozocin co-treated with Fructose] results in decreased expression of FSHB protein; Acetates inhibits the reaction [[Streptozocin co-treated with Fructose] results in decreased expression of FSHB protein]; carvacrol affects the reaction [Streptozocin results in decreased expression of FSHB protein]
CTD PMID:19931367 PMID:30365938 PMID:32153207 PMID:34656705 NCBI chr 2:106,886,331...106,889,996
Ensembl chr 2:106,886,485...106,890,001
JBrowse link
G Fshr follicle stimulating hormone receptor multiple interactions
decreases expression
ISO carvacrol affects the reaction [Streptozocin results in decreased expression of FSHR mRNA]; carvacrol affects the reaction [Streptozocin results in decreased expression of FSHR protein]
Streptozocin results in decreased expression of FSHR mRNA; Streptozocin results in decreased expression of FSHR protein
CTD PMID:32153207 NCBI chr17:89,292,380...89,508,103
Ensembl chr17:89,292,380...89,508,103
JBrowse link
G Fth1 ferritin heavy polypeptide 1 multiple interactions EXP [Dietary Fats co-treated with Streptozocin] results in increased expression of FTH1 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of FTH1 mRNA; omaveloxolone analog promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FTH1 mRNA]; omaveloxolone promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FTH1 mRNA] CTD PMID:32410268 PMID:38483099 NCBI chr19:9,957,964...9,962,475
Ensembl chr19:9,957,962...9,962,462
JBrowse link
G Ftl1 ferritin light polypeptide 1 multiple interactions EXP [Dietary Fats co-treated with Streptozocin] results in increased expression of FTL1 protein CTD PMID:38483099 NCBI chr 7:45,107,368...45,109,310
Ensembl chr 7:45,107,368...45,109,308
JBrowse link
G Fxyd2 FXYD domain-containing ion transport regulator 2 multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of FXYD2 mRNA CTD PMID:25905778 NCBI chr 9:45,311,007...45,321,576
Ensembl chr 9:45,310,967...45,321,576
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions
decreases activity
increases activity
increases expression
decreases expression
ISO
EXP
4-hydroxyphenylethanol inhibits the reaction [Streptozocin results in increased activity of G6PC1 protein]; bis(maltolato)oxovanadium(IV) inhibits the reaction [Streptozocin results in increased expression of G6PC1 mRNA]; citronellol inhibits the reaction [Streptozocin results in increased activity of G6PC1 protein]; Glyburide inhibits the reaction [Streptozocin results in increased activity of G6PC1 protein]; Phlorhizin inhibits the reaction [Streptozocin results in increased expression of G6PC1 mRNA]; Plant Extracts inhibits the reaction [Streptozocin results in decreased activity of G6PC1 protein]; Plant Extracts inhibits the reaction [Streptozocin results in increased expression of G6PC1 mRNA]; plumbagin inhibits the reaction [Streptozocin results in increased activity of G6PC1 protein]; Polysaccharides inhibits the reaction [Streptozocin results in decreased activity of G6PC1 protein]; Tribulus extract inhibits the reaction [Streptozocin results in increased expression of G6PC1 protein]; Trientine inhibits the reaction [Streptozocin results in increased expression of G6PC1 protein]
Streptozocin results in increased expression of G6PC1 mRNA; Streptozocin results in increased expression of G6PC1 protein
Streptozocin results in decreased expression of G6PC1 mRNA
[1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of G6PC1 protein]; [Dietary Fats co-treated with Streptozocin] results in decreased activity of G6PC1 protein; [Dietary Fats co-treated with Streptozocin] results in increased expression of G6PC1 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of G6PC1 mRNA; Acrylamide inhibits the reaction [Streptozocin results in increased expression of G6PC1 mRNA]; esculetin promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of G6PC1 protein]; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of G6PC1 mRNA]
CTD PMID:12446591 PMID:19634143 PMID:22960630 PMID:25446853 PMID:25641191 More... NCBI chr11:101,258,542...101,268,729
Ensembl chr11:101,258,387...101,268,729
JBrowse link
G G6pc3 glucose 6 phosphatase, catalytic, 3 multiple interactions
decreases activity
ISO Glyburide inhibits the reaction [Streptozocin results in decreased activity of G6PC3 protein]; Hesperidin inhibits the reaction [Streptozocin results in decreased activity of G6PC3 protein] CTD PMID:31345080 NCBI chr11:102,080,525...102,084,907
Ensembl chr11:102,080,446...102,084,907
JBrowse link
G G6pdx glucose-6-phosphate dehydrogenase X-linked multiple interactions
decreases activity
decreases expression
ISO
EXP
2-tert-butylhydroquinone inhibits the reaction [Streptozocin results in decreased expression of G6PD mRNA]; 2-tert-butylhydroquinone inhibits the reaction [Streptozocin results in decreased expression of G6PD protein]; 4-hydroxyphenylethanol inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]; [Dietary Fats co-treated with Streptozocin] results in decreased activity of G6PD protein; [Phytic Acid co-treated with Inositol] inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]; [Streptozocin co-treated with Cadmium] results in decreased activity of G6PD protein; [Streptozocin co-treated with Niacinamide] affects the activity of G6PD protein; arjunolic acid inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]; citronellol inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]; G6PD protein promotes the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; G6PD protein promotes the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; geraniol inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]; Gliclazide inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]; Glyburide inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]; Hesperidin inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased activity of G6PD protein]; nerolidol inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of G6PD protein]; NFE2L2 protein inhibits the reaction [Streptozocin results in decreased expression of G6PD mRNA]; NFE2L2 protein inhibits the reaction [Streptozocin results in decreased expression of G6PD protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] affects the activity of G6PD protein]
[Streptozocin co-treated with Dietary Fats] results in decreased activity of G6PD protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased activity of G6PD protein]
Streptozocin results in decreased expression of G6PD mRNA; Streptozocin results in decreased expression of G6PD protein
CTD PMID:19059388 PMID:19133311 PMID:19682444 PMID:24923654 PMID:25641191 More... NCBI chr  X:73,453,089...73,472,486
Ensembl chr  X:73,453,089...73,472,800
JBrowse link
G Gabra4 gamma-aminobutyric acid type A receptor subunit alpha 4 multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of GABRA4 mRNA CTD PMID:33484791 NCBI chr 5:71,727,077...71,815,651
Ensembl chr 5:71,727,092...71,815,651
JBrowse link
G Gabrr1 gamma-aminobutyric acid type A receptor subunit rho 1 multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of GABRR1 mRNA; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of GABRR1 mRNA] CTD PMID:32303808 NCBI chr 4:33,132,556...33,163,606
Ensembl chr 4:33,132,521...33,163,588
JBrowse link
G Gad1 glutamate decarboxylase 1 multiple interactions
decreases expression
ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of GAD1 protein; Curcumin inhibits the reaction [Streptozocin results in decreased expression of GAD1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in decreased expression of GAD1 mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of GAD1 protein] CTD PMID:23267840 PMID:35085591 NCBI chr 2:70,392,109...70,432,358
Ensembl chr 2:70,383,416...70,432,358
JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible 45 beta multiple interactions ISO
EXP
[resveratrol co-treated with Streptozocin] results in increased expression of GADD45B mRNA
[Streptozocin co-treated with Dietary Fats] results in increased expression of GADD45B mRNA
CTD PMID:25905778 PMID:29127188 NCBI chr10:80,765,925...80,768,038
Ensembl chr10:80,765,907...80,768,038
JBrowse link
G Galt galactose-1-phosphate uridyl transferase decreases expression ISO Streptozocin results in decreased expression of GALT mRNA CTD PMID:25905778 NCBI chr 4:41,755,517...41,759,243
Ensembl chr 4:41,755,228...41,758,695
JBrowse link
G Gas6 growth arrest specific 6 increases expression ISO Streptozocin results in increased expression of GAS6 protein CTD PMID:12644472 NCBI chr 8:13,515,374...13,544,535
Ensembl chr 8:13,515,374...13,544,490
JBrowse link
G Gatm glycine amidinotransferase (L-arginine:glycine amidinotransferase) multiple interactions
decreases expression
ISO Trientine inhibits the reaction [Streptozocin results in decreased expression of GATM protein] CTD PMID:19634143 NCBI chr 2:122,424,954...122,441,758
Ensembl chr 2:122,424,948...122,441,784
JBrowse link
G Gcg glucagon multiple interactions
decreases expression
ISO [Dietary Fats co-treated with Streptozocin] results in increased expression of GCG protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of GCG mRNA; Butyric Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GCG protein]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GCG protein]; rosiglitazone inhibits the reaction [Streptozocin results in decreased expression of GCG mRNA]; Sitagliptin Phosphate inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GCG mRNA] CTD PMID:18998217 PMID:23466488 PMID:27270450 NCBI chr 2:62,304,874...62,313,997
Ensembl chr 2:62,304,874...62,313,994
JBrowse link
G Gck glucokinase multiple interactions
decreases expression
EXP
ISO
[1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GCK protein]; [Dietary Fats co-treated with Streptozocin] results in decreased activity of GCK protein; [Dietary Fats co-treated with Streptozocin] results in decreased expression of GCK mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of GCK protein; [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of GCK protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of GCK mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of GCK protein; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GCK mRNA]
[Dietary Fats co-treated with Streptozocin] results in decreased activity of GCK protein; [Dietary Fats co-treated with Streptozocin] results in decreased expression of GCK mRNA; nerolidol inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of GCK protein]; Plant Extracts inhibits the reaction [Streptozocin results in decreased expression of GCK mRNA]; repaglinide analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GCK mRNA]; repaglinide inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GCK mRNA]
CTD PMID:25446853 PMID:26522834 PMID:27038876 PMID:27769711 PMID:29127188 More... NCBI chr11:5,850,816...5,900,081
Ensembl chr11:5,850,820...5,900,081
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions
decreases expression
ISO
EXP
[Streptozocin co-treated with Niacinamide] results in decreased expression of GCLC mRNA; [Streptozocin co-treated with Niacinamide] results in decreased expression of GCLC protein; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of GCLC mRNA]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of GCLC protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GCLC mRNA]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GCLC protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GCLC mRNA]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GCLC protein]
[Dietary Fats co-treated with Streptozocin] results in decreased expression of GCLC mRNA; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GCLC mRNA]
Streptozocin results in decreased expression of GCLC mRNA; Streptozocin results in decreased expression of GCLC protein
CTD PMID:21439372 PMID:33359794 PMID:33639173 NCBI chr 9:77,661,817...77,701,771
Ensembl chr 9:77,661,817...77,701,767
JBrowse link
G Gclm glutamate-cysteine ligase, modifier subunit multiple interactions EXP [Dietary Fats co-treated with Streptozocin] results in decreased expression of GCLM mRNA CTD PMID:33359794 NCBI chr 3:122,039,206...122,060,864
Ensembl chr 3:122,039,206...122,064,381
JBrowse link
G Gcnt2 glucosaminyl (N-acetyl) transferase 2 (I blood group) increases expression ISO Streptozocin results in increased expression of GCNT2 mRNA CTD PMID:25905778 NCBI chr13:41,013,417...41,114,368
Ensembl chr13:41,013,230...41,114,368
JBrowse link
G Gda guanine deaminase increases expression ISO Streptozocin results in increased expression of GDA mRNA CTD PMID:25905778 NCBI chr19:21,368,671...21,450,025
Ensembl chr19:21,368,671...21,450,809
JBrowse link
G Gdnf glial cell line derived neurotrophic factor multiple interactions
decreases expression
ISO Vitamin B 12 inhibits the reaction [Streptozocin results in decreased expression of GDNF protein] CTD PMID:38049026 NCBI chr15:7,839,529...7,867,061
Ensembl chr15:7,840,327...7,867,056
JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions
increases expression
decreases expression
ISO
EXP
Ibuprofen inhibits the reaction [Streptozocin results in increased expression of GFAP mRNA]; Ibuprofen inhibits the reaction [Streptozocin results in increased expression of GFAP protein]; Memantine inhibits the reaction [Streptozocin results in increased expression of GFAP mRNA]; Memantine inhibits the reaction [Streptozocin results in increased expression of GFAP protein]; Vitamin B 12 inhibits the reaction [Streptozocin results in increased expression of GFAP protein]
Streptozocin results in increased expression of GFAP mRNA; Streptozocin results in increased expression of GFAP protein
Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of GFAP protein]; Physostigmine inhibits the reaction [Streptozocin results in decreased expression of GFAP protein]
CTD PMID:24333387 PMID:28499986 PMID:38049026 NCBI chr11:102,778,162...102,791,368
Ensembl chr11:102,778,162...102,791,738
JBrowse link
G Gfm1 G elongation factor, mitochondrial 1 affects expression EXP Streptozocin affects the expression of GFM1 mRNA CTD PMID:18583417 NCBI chr 3:67,337,448...67,382,401
Ensembl chr 3:67,337,429...67,383,862
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 decreases expression
multiple interactions
ISO Streptozocin results in decreased expression of GGT1 protein
[resveratrol co-treated with Streptozocin] results in increased expression of GGT1 mRNA; Trientine inhibits the reaction [Streptozocin results in decreased expression of GGT1 protein]
CTD PMID:19634143 PMID:25905778 NCBI chr10:75,396,910...75,422,027
Ensembl chr10:75,397,438...75,422,034
JBrowse link
G Ghr growth hormone receptor multiple interactions ISO [resveratrol co-treated with Streptozocin] results in decreased expression of GHR mRNA CTD PMID:25905778 NCBI chr15:3,347,237...3,612,834
Ensembl chr15:3,347,242...3,612,974
JBrowse link
G Ghrl ghrelin multiple interactions ISO GHRL protein promotes the reaction [Streptozocin results in decreased expression of CARTPT mRNA]; GHRL protein promotes the reaction [Streptozocin results in decreased expression of FASN mRNA]; GHRL protein promotes the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA] CTD PMID:20219977 NCBI chr 6:113,693,080...113,696,872
Ensembl chr 6:113,693,080...113,696,841
JBrowse link
G Gk glycerol kinase decreases expression
multiple interactions
ISO
EXP
Streptozocin results in decreased expression of GK mRNA
[Dietary Fats co-treated with Streptozocin] results in increased expression of GK mRNA; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GK mRNA]
CTD PMID:25905778 PMID:33812996 NCBI chr  X:84,745,543...84,820,425
Ensembl chr  X:84,745,543...84,820,425
JBrowse link
G Glb1 galactosidase, beta 1 multiple interactions
increases expression
EXP 2-amino-6-boronohexanoic acid inhibits the reaction [Streptozocin results in increased expression of GLB1 protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of GLB1 protein; ARG1 gene mutant form inhibits the reaction [Streptozocin results in increased expression of GLB1 protein] CTD PMID:29673160 PMID:38483099 NCBI chr 9:114,230,146...114,303,447
Ensembl chr 9:114,230,144...114,303,966
JBrowse link
G Glis1 GLIS family zinc finger 1 multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of GLIS1 mRNA CTD PMID:33484791 NCBI chr 4:107,283,840...107,492,258
Ensembl chr 4:107,291,788...107,492,258
JBrowse link
G Glo1 glyoxalase 1 multiple interactions ISO [Streptozocin co-treated with Niacinamide] results in decreased activity of GLO1 protein; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of GLO1 protein]; resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of GLO1 protein] CTD PMID:21439372 NCBI chr17:30,811,835...30,831,633
Ensembl chr17:30,803,910...30,845,845
JBrowse link
G Glp1r glucagon-like peptide 1 receptor multiple interactions ISO [Fructose co-treated with Streptozocin] results in decreased expression of GLP1R mRNA; Ghrelin inhibits the reaction [[Fructose co-treated with Streptozocin] results in decreased expression of GLP1R mRNA] CTD PMID:31468622 NCBI chr17:31,120,841...31,155,484
Ensembl chr17:31,120,791...31,159,765
JBrowse link
G Glud1 glutamate dehydrogenase 1 multiple interactions ISO [Dietary Fats co-treated with Streptozocin] results in decreased expression of GLUD1 mRNA; repaglinide analog affects the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GLUD1 mRNA]; repaglinide inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GLUD1 mRNA] CTD PMID:35702883 NCBI chr14:34,032,684...34,066,990
Ensembl chr14:34,032,684...34,067,222
JBrowse link
G Glul glutamate-ammonia ligase multiple interactions
decreases expression
ISO [resveratrol co-treated with Streptozocin] results in increased expression of GLUL mRNA; resveratrol inhibits the reaction [Streptozocin results in decreased expression of GLUL mRNA]; resveratrol inhibits the reaction [Streptozocin results in decreased expression of GLUL protein]
Streptozocin results in decreased expression of GLUL mRNA; Streptozocin results in decreased expression of GLUL protein
CTD PMID:25905778 PMID:26677078 NCBI chr 1:153,775,692...153,785,469
Ensembl chr 1:153,775,690...153,785,469
JBrowse link
G Gna11 guanine nucleotide binding protein, alpha 11 multiple interactions
increases expression
ISO acetovanillone inhibits the reaction [Streptozocin results in increased expression of GNA11 protein]; CAT protein inhibits the reaction [Streptozocin results in increased expression of GNA11 protein] CTD PMID:20691780 NCBI chr10:81,364,558...81,380,996
Ensembl chr10:81,364,558...81,381,024
JBrowse link
G Gnai2 G protein subunit alpha i2 multiple interactions
decreases expression
ISO Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of GNAI2 protein]; diphenyleneiodonium inhibits the reaction [Streptozocin results in decreased expression of GNAI2 protein] CTD PMID:18441196 NCBI chr 9:107,491,324...107,512,542
Ensembl chr 9:107,491,324...107,512,566
JBrowse link
G Gnai3 G protein subunit alpha i3 multiple interactions
decreases expression
ISO Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of GNAI3 protein]; diphenyleneiodonium inhibits the reaction [Streptozocin results in decreased expression of GNAI3 protein] CTD PMID:18441196 NCBI chr 3:108,014,591...108,053,468
Ensembl chr 3:108,014,596...108,053,462
JBrowse link
G Gnaq guanine nucleotide binding protein, alpha q polypeptide multiple interactions
increases expression
ISO acetovanillone inhibits the reaction [Streptozocin results in increased expression of GNAQ protein]; CAT protein inhibits the reaction [Streptozocin results in increased expression of GNAQ protein] CTD PMID:20691780 NCBI chr19:16,110,048...16,365,884
Ensembl chr19:16,110,195...16,364,827
JBrowse link
G Gngt1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of GNGT1 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of GNGT1 mRNA] CTD PMID:33484791 NCBI chr 6:3,989,082...3,997,441
Ensembl chr 6:3,993,792...3,997,436
JBrowse link
G Gnmt glycine N-methyltransferase multiple interactions
increases activity
increases expression
ISO Folic Acid inhibits the reaction [Streptozocin results in increased activity of GNMT protein]
Streptozocin results in increased expression of GNMT mRNA; Streptozocin results in increased expression of GNMT protein
CTD PMID:16835399 NCBI chr17:47,036,590...47,040,091
Ensembl chr17:47,036,590...47,040,094
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1, soluble multiple interactions
increases secretion
ISO
EXP
[Resveratrol co-treated with Streptozocin] results in decreased expression of GOT1 mRNA; Atorvastatin inhibits the reaction [Streptozocin results in increased secretion of GOT1 protein]
[Streptozocin co-treated with Dietary Fats] results in increased expression of GOT1 protein; [Streptozocin co-treated with Dietary Fats] results in increased secretion of GOT1 protein; aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased secretion of GOT1 protein]; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of GOT1 protein]
CTD PMID:25905778 PMID:30657622 PMID:35961541 PMID:37482253 NCBI chr19:43,488,191...43,514,743
Ensembl chr19:43,488,191...43,513,044
JBrowse link
G Got2 glutamatic-oxaloacetic transaminase 2, mitochondrial increases expression
multiple interactions
ISO Streptozocin results in increased expression of GOT2 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of GOT2 protein]
CTD PMID:19634143 NCBI chr 8:96,590,761...96,615,029
Ensembl chr 8:96,590,762...96,615,175
JBrowse link
G Gpc1 glypican 1 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of GPC1 mRNA CTD PMID:29127188 NCBI chr 1:92,759,367...92,787,933
Ensembl chr 1:92,759,367...92,788,501
JBrowse link
G Gpd1 glycerol-3-phosphate dehydrogenase 1 (soluble) multiple interactions ISO [resveratrol co-treated with Streptozocin] results in decreased expression of GPD1 mRNA CTD PMID:25905778 NCBI chr15:99,615,468...99,622,895
Ensembl chr15:99,615,396...99,622,886
JBrowse link
G Gprc6a G protein-coupled receptor, family C, group 6, member A multiple interactions ISO [Dietary Fats co-treated with Streptozocin] results in decreased expression of GPRC6A mRNA; Warfarin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GPRC6A mRNA] CTD PMID:27488359 NCBI chr10:51,490,919...51,507,554
Ensembl chr10:51,490,919...51,507,557
JBrowse link
G Gpt glutamic pyruvic transaminase, soluble multiple interactions
increases expression
increases activity
increases secretion
ISO
EXP
4-hydroxyisoleucine inhibits the reaction [Streptozocin results in increased expression of GPT protein]; [Dietary Fats co-treated with Streptozocin] results in increased activity of GPT protein; [Dietary Fats co-treated with Streptozocin] results in increased expression of GPT protein; [Streptozocin co-treated with Dietary Fats] results in increased activity of GPT protein; [Zinc co-treated with Selenium] inhibits the reaction [Streptozocin results in increased expression of GPT protein]; allyl isothiocyanate inhibits the reaction [Streptozocin promotes the reaction [Dietary Fats results in increased expression of GPT protein]]; Atorvastatin inhibits the reaction [Streptozocin results in increased secretion of GPT protein]; dapagliflozin inhibits the reaction [Streptozocin results in increased expression of GPT protein]; Ellagic Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GPT protein]; Eugenol inhibits the reaction [Streptozocin results in increased expression of GPT protein]; Ficusin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased activity of GPT protein]; Fungal Polysaccharides inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased activity of GPT protein]; Glyburide inhibits the reaction [Streptozocin results in increased activity of GPT protein]; mangiferin inhibits the reaction [Streptozocin results in increased activity of GPT protein]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased activity of GPT protein]; morin analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased activity of GPT protein]; naringenin inhibits the reaction [Streptozocin results in increased activity of GPT protein]; nerolidol inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased activity of GPT protein]; Pioglitazone inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased activity of GPT protein]; Plant Extracts inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased activity of GPT protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of GPT protein]; sodium tungstate(VI) inhibits the reaction [Streptozocin results in increased activity of GPT protein]; Streptozocin promotes the reaction [Dietary Fats results in increased expression of GPT protein]; Tribulus extract inhibits the reaction [Streptozocin results in increased activity of GPT protein]; Zinc Compounds inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased activity of GPT protein]
[Acrylamide co-treated with Streptozocin] results in increased activity of GPT protein; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of GPT protein; [omaveloxolone analog co-treated with Streptozocin co-treated with Dietary Fats] results in increased expression of GPT protein; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of GPT protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of GPT protein; [Streptozocin co-treated with Dietary Fats] results in increased secretion of GPT protein; aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased secretion of GPT protein]; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of GPT protein]; Metformin inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of GPT protein]; perilla seed oil inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of GPT protein]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of GPT protein]
CTD PMID:11357483 PMID:24854284 PMID:24877639 PMID:26071184 PMID:27350165 More... NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions
decreases activity
decreases expression
increases expression
EXP
ISO
[Dietary Fats co-treated with Streptozocin] results in decreased expression of GPX1 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of GPX1 protein; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of GPX1 protein]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GPX1 mRNA]; Sodium Selenite inhibits the reaction [Streptozocin results in decreased activity of GPX1 protein]; Sodium Selenite inhibits the reaction [Streptozocin results in decreased expression of GPX1 mRNA]
Streptozocin results in increased expression of GPX1 protein
[[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in decreased expression of GPX1 mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of GPX1 mRNA; [Carbamazepine affects the susceptibility to [Dietary Fats co-treated with Streptozocin]] which results in decreased expression of GPX1 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of GPX1 mRNA; allyl methyl sulfide inhibits the reaction [Streptozocin results in decreased activity of GPX1 protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of GPX1 mRNA]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of GPX1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in decreased expression of GPX1 mRNA]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of GPX1 mRNA]; Trientine inhibits the reaction [Streptozocin results in increased expression of GPX1 protein]
CTD PMID:18789669 PMID:19634143 PMID:23267840 PMID:24740756 PMID:30318971 More... NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542
JBrowse link
G Gpx2 glutathione peroxidase 2 multiple interactions ISO [[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in increased expression of GPX2 mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in increased expression of GPX2 mRNA; [Carbamazepine affects the susceptibility to [Dietary Fats co-treated with Streptozocin]] which results in increased expression of GPX2 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in increased expression of GPX2 mRNA; [Resveratrol co-treated with Streptozocin] results in increased expression of GPX2 mRNA CTD PMID:25905778 PMID:35786680 NCBI chr12:76,839,109...76,842,328
Ensembl chr12:76,839,107...76,842,273
JBrowse link
G Gpx3 glutathione peroxidase 3 increases expression
multiple interactions
ISO Streptozocin results in increased expression of GPX3 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of GPX3 protein]
CTD PMID:19634143 NCBI chr11:54,793,680...54,801,213
Ensembl chr11:54,793,279...54,801,203
JBrowse link
G Gpx4 glutathione peroxidase 4 multiple interactions
decreases expression
EXP
ISO
[Dietary Fats co-treated with Streptozocin] results in decreased expression of GPX4 mRNA; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GPX4 mRNA]
Streptozocin results in decreased expression of GPX4 protein
[Zinc co-treated with Selenium] inhibits the reaction [Streptozocin results in decreased expression of GPX4 protein]
CTD PMID:32233808 PMID:33359794 NCBI chr10:79,883,000...79,892,273
Ensembl chr10:79,883,000...79,892,273
JBrowse link
G Gpx5 glutathione peroxidase 5 decreases expression
multiple interactions
ISO Streptozocin results in decreased expression of GPX5 protein
[Zinc co-treated with Selenium] inhibits the reaction [Streptozocin results in decreased expression of GPX5 protein]
CTD PMID:32233808 NCBI chr13:21,470,599...21,476,897
Ensembl chr13:21,470,599...21,476,901
JBrowse link
G Gramd2a GRAM domain containing 2A multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of GRAMD2A mRNA CTD PMID:33484791 NCBI chr 9:59,587,116...59,626,156
Ensembl chr 9:59,587,427...59,626,157
JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist increases expression ISO Streptozocin results in increased expression of GREM1 mRNA CTD PMID:10744662 NCBI chr 2:113,579,020...113,588,993
Ensembl chr 2:113,576,509...113,588,991
JBrowse link
G Gria4 glutamate receptor, ionotropic, AMPA4 (alpha 4) multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Streptozocin results in increased expression of GRIA4 protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of GRIA4 protein] CTD PMID:23267840 NCBI chr 9:4,417,893...4,796,250
Ensembl chr 9:4,417,896...4,796,234
JBrowse link
G Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Streptozocin results in increased expression of GRIN1 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of GRIN1 protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of GRIN1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of GRIN1 protein]
Streptozocin results in increased expression of GRIN1 mRNA; Streptozocin results in increased expression of GRIN1 protein
CTD PMID:23267840 NCBI chr 2:25,181,189...25,209,199
Ensembl chr 2:25,181,193...25,209,199
JBrowse link
G Grk2 G protein-coupled receptor kinase 2 increases localization
multiple interactions
ISO Streptozocin results in increased localization of GRK2 protein
tempol inhibits the reaction [Streptozocin results in increased localization of GRK2 protein]
CTD PMID:16478977 NCBI chr19:4,336,029...4,356,356
Ensembl chr19:4,336,029...4,356,250
JBrowse link
G Grm5 glutamate receptor, metabotropic 5 increases expression ISO Streptozocin results in increased expression of GRM5 protein CTD PMID:19840219 NCBI chr 7:87,233,212...87,784,271
Ensembl chr 7:87,233,376...87,784,115
JBrowse link
G Gsdmd gasdermin D multiple interactions
increases expression
affects response to substance
EXP
ISO
[Dietary Fats co-treated with Streptozocin] results in increased expression of GSDMD mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of GSDMD protein; GSDMD protein affects the reaction [Streptozocin results in increased cleavage of CASP1 protein]; GSDMD protein affects the reaction [Streptozocin results in increased expression of IL18 protein]; GSDMD protein affects the reaction [Streptozocin results in increased expression of IL1B protein]; Hirudins inhibits the reaction [Streptozocin results in increased expression of and results in increased cleavage of GSDMD protein]; Hirudins inhibits the reaction [Streptozocin results in increased expression of GSDMD mRNA]; loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GSDMD mRNA]; loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GSDMD protein]; Streptozocin results in increased expression of and results in increased cleavage of GSDMD protein
GSDMD protein affects the susceptibility to Streptozocin
Streptozocin results in increased expression of GSDMD protein
scutellarin inhibits the reaction [Streptozocin results in increased expression of GSDMD protein]
CTD PMID:34212273 PMID:37081038 PMID:37473909 NCBI chr15:75,733,990...75,739,257
Ensembl chr15:75,734,176...75,739,257
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases phosphorylation
multiple interactions
increases expression
ISO
EXP
Streptozocin results in decreased phosphorylation of GSK3B protein
[Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in decreased phosphorylation of GSK3B protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of GSK3B protein; Curcumin inhibits the reaction [Streptozocin results in decreased phosphorylation of GSK3B protein]; hesperetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of GSK3B protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in decreased phosphorylation of GSK3B protein]; Phosphocreatine inhibits the reaction [Streptozocin results in decreased phosphorylation of GSK3B protein]; Plant Extracts inhibits the reaction [[Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in decreased phosphorylation of GSK3B protein]; Plant Extracts inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of GSK3B protein]; Plant Extracts inhibits the reaction [Streptozocin results in increased expression of GSK3B mRNA]; Quercetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of GSK3B protein]; Streptozocin results in decreased expression of and results in decreased phosphorylation of GSK3B protein; STUB1 inhibits the reaction [Streptozocin results in decreased expression of and results in decreased phosphorylation of GSK3B protein]; Tribulus extract inhibits the reaction [Streptozocin results in decreased phosphorylation of GSK3B protein]
5-Methoxypsoralen inhibits the reaction [Streptozocin results in decreased phosphorylation of GSK3B protein]; [Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of GSK3B protein; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the phosphorylation of GSK3B protein; [Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of GSK3B protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of GSK3B protein]; Metformin inhibits the reaction [Streptozocin results in decreased phosphorylation of GSK3B protein]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of GSK3B protein]; phillyrin inhibits the reaction [Streptozocin results in decreased phosphorylation of GSK3B protein]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the phosphorylation of GSK3B protein]; Tadalafil inhibits the reaction [Streptozocin results in decreased phosphorylation of GSK3B protein]
CTD PMID:25541178 PMID:27038876 PMID:28422052 PMID:31877369 PMID:33484791 More... NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446
JBrowse link
G Gspt2 G1 to S phase transition 2 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of GSPT2 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of GSPT2 mRNA] CTD PMID:33484791 NCBI chr  X:93,679,675...93,682,168
Ensembl chr  X:93,679,675...93,686,850
JBrowse link
G Gsr glutathione reductase multiple interactions
decreases activity
increases activity
affects activity
decreases expression
ISO [Carmustine results in decreased activity of GSR protein] which results in increased susceptibility to Streptozocin; [Dietary Fats co-treated with Streptozocin] results in decreased activity of GSR protein; [Niacinamide co-treated with Streptozocin] results in decreased activity of GSR protein; [Streptozocin co-treated with Dietary Fats] results in decreased activity of GSR protein; [Streptozocin co-treated with Niacinamide] results in decreased activity of GSR protein; [Zinc Sulfate results in increased abundance of Zinc] inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; Acetylcysteine inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; arjunolic acid inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; Bezafibrate inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; caryophyllene inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; Chromium inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; chromium tripicolinate inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; Ellagic Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of GSR protein]; Gallic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased activity of GSR protein]; geraniol inhibits the reaction [Streptozocin affects the activity of GSR protein]; Gliclazide inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in decreased activity of GSR protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of GSR protein]; Glyburide inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of GSR protein]; INS protein promotes the reaction [Streptozocin results in increased activity of GSR protein]; Metformin inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; morin inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; piperlongumine inhibits the reaction [Streptozocin results in decreased expression of GSR protein]; Resveratrol inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in decreased activity of GSR protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of GSR protein]; Rosiglitazone inhibits the reaction [Streptozocin promotes the reaction [Dietary Fats results in decreased activity of GSR protein]]; Sodium Selenite inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; Streptozocin promotes the reaction [Dietary Fats results in decreased activity of GSR protein]; Zinc inhibits the reaction [Streptozocin results in decreased activity of GSR protein] CTD PMID:11424224 PMID:15720826 PMID:17145126 PMID:19682444 PMID:19840221 More... NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191
JBrowse link
G Gsta1 glutathione S-transferase, alpha 1 (Ya) multiple interactions
increases expression
ISO [resveratrol co-treated with Streptozocin] results in increased expression of GSTA5 mRNA
Streptozocin results in increased expression of GSTA5 mRNA
CTD PMID:25905778 NCBI chr 9:78,137,951...78,149,965
Ensembl chr 9:78,137,938...78,149,966
JBrowse link
G Gsta2 glutathione S-transferase, alpha 2 (Yc2) increases expression
multiple interactions
ISO Streptozocin results in increased expression of GSTA2 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of GSTA2 protein]
CTD PMID:19634143 NCBI chr 9:78,238,300...78,254,474
Ensembl chr 9:78,238,300...78,263,070
JBrowse link
G Gsta4 glutathione S-transferase, alpha 4 increases expression ISO Streptozocin results in increased expression of GSTA4 protein CTD PMID:14693714 NCBI chr 9:78,099,248...78,116,631
Ensembl chr 9:78,090,056...78,116,631
JBrowse link
G Gstm2 glutathione S-transferase, mu 2 increases expression
multiple interactions
ISO Streptozocin results in increased expression of GSTM2 mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of GSTM2 mRNA]
CTD PMID:16684804 NCBI chr 3:107,889,018...107,893,736
Ensembl chr 3:107,889,018...107,893,769
JBrowse link
G Gstm5 glutathione S-transferase, mu 5 multiple interactions ISO [Streptozocin co-treated with Niacinamide] results in decreased expression of GSTM3 mRNA; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GSTM3 mRNA]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GSTM3 mRNA] CTD PMID:21439372 NCBI chr 3:107,803,240...107,806,002
Ensembl chr 3:107,803,137...107,806,002
JBrowse link
G Gstp1 glutathione S-transferase, pi 1 decreases expression ISO Streptozocin results in decreased expression of GSTP1 mRNA CTD PMID:25905778 NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985
JBrowse link
G Gucy1b2 guanylate cyclase 1, soluble, beta 2 decreases expression ISO Streptozocin results in decreased expression of GUCY1B2 mRNA CTD PMID:25905778 NCBI chr14:62,610,384...62,693,745
Ensembl chr14:62,630,125...62,693,738
JBrowse link
G Gys1 glycogen synthase 1, muscle decreases expression
multiple interactions
increases phosphorylation
ISO Streptozocin results in decreased expression of GYS1 mRNA
Plant Extracts inhibits the reaction [Streptozocin results in decreased expression of GYS1 mRNA]; Tribulus extract inhibits the reaction [Streptozocin results in increased phosphorylation of GYS1 protein]
CTD PMID:27038876 PMID:36627075 NCBI chr 7:45,084,263...45,106,041
Ensembl chr 7:45,084,268...45,106,043
JBrowse link
G Gys2 glycogen synthase 2 multiple interactions ISO [Streptozocin co-treated with Niacinamide] affects the activity of GYS2 protein; resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] affects the activity of GYS2 protein] CTD PMID:19059388 NCBI chr 6:142,368,339...142,418,856
Ensembl chr 6:142,368,339...142,418,835
JBrowse link
G H19 H19, imprinted maternally expressed transcript multiple interactions ISO [Resveratrol co-treated with Streptozocin] results in increased expression of H19 mRNA CTD PMID:25905778 NCBI chr 7:142,129,267...142,131,883
Ensembl chr 7:142,129,262...142,133,957
JBrowse link
G H2-DMa histocompatibility 2, class II, locus DMa multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of RT1-DMA mRNA CTD PMID:25905778 NCBI chr17:34,338,667...34,358,075
Ensembl chr17:34,338,515...34,358,075
JBrowse link
G H2-DMb1 histocompatibility 2, class II, locus Mb1 multiple interactions ISO [Resveratrol co-treated with Streptozocin] results in increased expression of RT1-DMB mRNA CTD PMID:25905778 NCBI chr17:34,372,165...34,379,203
Ensembl chr17:34,372,046...34,379,204
JBrowse link
G H2bc15 H2B clustered histone 15 multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of H2BC14 mRNA CTD PMID:33484791 NCBI chr13:21,938,246...21,938,723
Ensembl chr13:21,938,293...21,938,673
JBrowse link
G H2bc3 H2B clustered histone 3 multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of H2BC3 mRNA CTD PMID:33484791 NCBI chr13:23,930,717...23,931,206
Ensembl chr13:23,930,717...23,931,224
JBrowse link
G H3c2 H3 clustered histone 2 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of H3C2 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of H3C2 mRNA] CTD PMID:33484791 NCBI chr13:23,936,328...23,936,823
Ensembl chr13:23,936,250...23,936,869
JBrowse link
G Hamp hepcidin antimicrobial peptide multiple interactions ISO [Streptozocin co-treated with iron pentacarbonyl] results in increased expression of HAMP mRNA CTD PMID:22170771 NCBI chr 7:30,641,793...30,643,454
Ensembl chr 7:30,641,793...30,643,457
JBrowse link
G Hao2 hydroxyacid oxidase 2 multiple interactions
decreases expression
ISO [resveratrol co-treated with Streptozocin] results in decreased expression of HAO2 mRNA; Trientine inhibits the reaction [Streptozocin results in decreased expression of HAO2 protein]
Streptozocin results in decreased expression of HAO2 mRNA; Streptozocin results in decreased expression of HAO2 protein
CTD PMID:19634143 PMID:25905778 NCBI chr 3:98,781,835...98,802,692
Ensembl chr 3:98,781,837...98,800,555
JBrowse link
G Hapln1 hyaluronan and proteoglycan link protein 1 multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of HAPLN1 mRNA CTD PMID:33484791 NCBI chr13:89,688,654...89,759,951
Ensembl chr13:89,687,915...89,759,771
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 decreases expression
multiple interactions
increases expression
EXP
ISO
Streptozocin results in decreased expression of HAVCR1 mRNA
[Streptozocin co-treated with Fructose] results in increased expression of HAVCR1 protein; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of HAVCR1 protein]; dapagliflozin promotes the reaction [Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of HAVCR1 protein]]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of HAVCR1 protein]; Metformin promotes the reaction [dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of HAVCR1 protein]]; sulbutiamine inhibits the reaction [Streptozocin results in increased expression of HAVCR1 protein]
CTD PMID:19516248 PMID:30551545 PMID:37224990 NCBI chr11:46,630,644...46,670,405
Ensembl chr11:46,625,907...46,670,405
JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 multiple interactions
increases glycation
ISO [Streptozocin co-treated with Niacinamide] results in increased glycosylation of HBA1 protein; coumarin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased glycosylation of HBA1 protein]
Streptozocin results in increased glycation of HBA1 protein
CTD PMID:19647726 PMID:21139377 NCBI chr11:32,246,492...32,247,310
Ensembl chr11:32,246,489...32,247,298
JBrowse link
G Hbb-b1 hemoglobin, beta adult major chain decreases expression
multiple interactions
ISO Streptozocin results in decreased expression of HBB-B1 protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of HBB-B1 protein]
CTD PMID:19634143
G Hck hemopoietic cell kinase multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of HCK mRNA CTD PMID:25905778 NCBI chr 2:152,950,388...152,993,361
Ensembl chr 2:152,950,388...152,993,361
JBrowse link
G Hdac3 histone deacetylase 3 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of HDAC3 protein; HDAC3 protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of MIR10A mRNA]; HDAC3 protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CREB1 protein]; HDAC3 protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein] CTD PMID:27292126 NCBI chr18:38,070,024...38,088,073
Ensembl chr18:38,068,897...38,088,069
JBrowse link
G Hdac5 histone deacetylase 5 multiple interactions ISO [Streptozocin co-treated with Fructose] results in increased expression of HDAC5 protein; Acetates inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of HDAC5 protein] CTD PMID:34656705 NCBI chr11:102,085,244...102,120,968
Ensembl chr11:102,085,258...102,120,992
JBrowse link
G Hesx1 homeobox gene expressed in ES cells multiple interactions EXP [Diethylhexyl Phthalate co-treated with Streptozocin co-treated with Dietary Fats] results in decreased expression of HESX1 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of HESX1 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of HESX1 mRNA] CTD PMID:33484791 NCBI chr14:26,716,322...26,724,286
Ensembl chr14:26,716,373...26,724,286
JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit increases expression
multiple interactions
EXP
ISO
Streptozocin results in increased expression of HIF1A protein
[Streptozocin co-treated with Dietary Fats] results in increased expression of HIF1A protein; bicalutamide promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of HIF1A protein]; Insulin promotes the reaction [Ozone inhibits the reaction [Streptozocin results in increased expression of HIF1A mRNA]]; Ozone inhibits the reaction [Streptozocin results in increased expression of HIF1A mRNA]
CTD PMID:26073000 PMID:26614261 PMID:35151640 NCBI chr12:73,948,186...73,994,304
Ensembl chr12:73,948,149...73,994,304
JBrowse link
G Hk1 hexokinase 1 decreases activity
multiple interactions
ISO Streptozocin results in decreased activity of HK1 protein
[homocastasterone analog co-treated with Streptozocin] results in increased expression of HK1 mRNA; plumbagin inhibits the reaction [Streptozocin results in decreased activity of HK1 protein]
CTD PMID:22960630 PMID:28822685 NCBI chr10:62,104,634...62,215,699
Ensembl chr10:62,104,634...62,215,687
JBrowse link
G Hmgb1 high mobility group box 1 increases expression
multiple interactions
EXP Streptozocin results in increased expression of HMGB1 mRNA
manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Streptozocin results in increased expression of HMGB1 mRNA]
CTD PMID:19833897 NCBI chr 5:148,983,512...148,989,867
Ensembl chr 5:148,983,512...149,121,299
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase multiple interactions
increases expression
ISO
EXP
[Dietary Fats co-treated with Streptozocin] results in increased expression of HMGCR mRNA; [Streptozocin co-treated with Cadmium] results in increased activity of HMGCR protein; [Streptozocin co-treated with Niacinamide] results in increased activity of HMGCR protein; [tetrahydrocurcumin co-treated with Chlorogenic Acid] results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in increased activity of HMGCR protein]; Chlorogenic Acid results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in increased activity of HMGCR protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased activity of HMGCR protein]; tetrahydrocurcumin results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in increased activity of HMGCR protein]; Warfarin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of HMGCR mRNA]
Streptozocin results in increased expression of HMGCR mRNA
Acrylamide inhibits the reaction [Streptozocin results in increased expression of HMGCR mRNA]
CTD PMID:20696151 PMID:25240712 PMID:25905778 PMID:27488359 PMID:34896238 NCBI chr13:96,785,470...96,807,444
Ensembl chr13:96,785,475...96,807,444
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 increases expression
multiple interactions
ISO Streptozocin results in increased expression of HMGCS2 mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of HMGCS2 mRNA]
CTD PMID:16684804 NCBI chr 3:98,187,747...98,218,054
Ensembl chr 3:98,187,751...98,218,054
JBrowse link
G Hmox1 heme oxygenase 1 decreases activity
multiple interactions
increases expression
decreases expression
ISO
EXP
Streptozocin results in decreased activity of HMOX1 protein
[cobaltiprotoporphyrin co-treated with Streptozocin] results in increased activity of HMOX1 protein; [cobaltiprotoporphyrin co-treated with Streptozocin] results in increased expression of HMOX1 protein; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of HMOX1 mRNA; [Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of HMOX1 protein]; [Streptozocin co-treated with Dietary Fats] results in decreased expression of HMOX1 protein; [Streptozocin co-treated with Hemin] results in increased activity of HMOX1 protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of HMOX1 protein; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of HMOX1 mRNA]; caffeic acid phenethyl ester inhibits the reaction [Streptozocin results in increased expression of HMOX1 protein]; chromium mesoporphyrin inhibits the reaction [[Streptozocin co-treated with Hemin] results in increased activity of HMOX1 protein]; cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of and results in decreased activity of HMOX1 protein]; cobaltiprotoporphyrin promotes the reaction [Streptozocin results in increased expression of HMOX1 protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein]; diallyl trisulfide inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein]; Dimethyl Fumarate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of HMOX1 protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of HMOX1 mRNA]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of HMOX1 protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of HMOX1 mRNA]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of HMOX1 protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of HMOX1 mRNA]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of HMOX1 mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of HMOX1 protein]; Metformin inhibits the reaction [Streptozocin results in decreased expression of HMOX1 mRNA]; Metformin inhibits the reaction [Streptozocin results in increased expression of HMOX1 mRNA]; palbinone inhibits the reaction [Streptozocin results in decreased expression of HMOX1 mRNA]; Propofol inhibits the reaction [Streptozocin results in decreased activity of HMOX1 protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of HMOX1 protein]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of HMOX1 mRNA]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein]; Streptozocin results in decreased expression of and results in decreased activity of HMOX1 protein; Streptozocin results in increased expression of and results in decreased activity of HMOX1 protein; STUB1 inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of HMOX1 mRNA]; tin mesoporphyrin inhibits the reaction [[cobaltiprotoporphyrin co-treated with Streptozocin] results in increased activity of HMOX1 protein]; tin mesoporphyrin inhibits the reaction [[cobaltiprotoporphyrin co-treated with Streptozocin] results in increased expression of HMOX1 protein]
Streptozocin results in increased expression of HMOX1 mRNA; Streptozocin results in increased expression of HMOX1 protein
HMOX1 protein inhibits the reaction [Streptozocin results in decreased expression of SLC25A19 protein]
[Dietary Fats co-treated with Streptozocin] results in decreased expression of HMOX1 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of HMOX1 mRNA; [Streptozocin co-treated with sulforaphane] results in increased expression of HMOX1; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of HMOX1 mRNA]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of HMOX1 mRNA]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of HMOX1 mRNA]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein]
Streptozocin results in decreased expression of HMOX1 mRNA; Streptozocin results in decreased expression of HMOX1 protein
CTD PMID:16309587 PMID:16595661 PMID:19019021 PMID:19190261 PMID:21439372 More... NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Hmox2 heme oxygenase 2 multiple interactions
increases response to substance
EXP cobaltiprotoporphyrin inhibits the reaction [HMOX2 gene mutant form results in increased susceptibility to Streptozocin]; tin mesoporphyrin promotes the reaction [HMOX2 gene mutant form results in increased susceptibility to Streptozocin] CTD PMID:16524951 NCBI chr16:4,544,225...4,584,606
Ensembl chr16:4,544,225...4,584,606
JBrowse link
G Hnf4a hepatic nuclear factor 4, alpha multiple interactions
increases expression
EXP Acrylamide inhibits the reaction [Streptozocin results in increased expression of HNF4A mRNA] CTD PMID:34896238 NCBI chr 2:163,348,731...163,414,827
Ensembl chr 2:163,348,728...163,414,830
JBrowse link
G Hopx HOP homeobox multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of HOPX mRNA CTD PMID:25905778 NCBI chr 5:77,234,831...77,262,970
Ensembl chr 5:77,234,835...77,262,968
JBrowse link
G Hp haptoglobin multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of HP mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of HP mRNA] CTD PMID:33484791 NCBI chr 8:110,301,760...110,305,804
Ensembl chr 8:110,301,760...110,305,804
JBrowse link
G Hras Harvey rat sarcoma virus oncogene decreases farnesylation ISO Streptozocin results in decreased farnesylation of HRAS protein CTD PMID:19002579 NCBI chr 7:140,770,839...140,773,938
Ensembl chr 7:140,769,018...140,773,918
JBrowse link
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 decreases expression
multiple interactions
ISO Streptozocin results in decreased expression of HSD17B10 protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of HSD17B10 protein]
CTD PMID:21136691 NCBI chr  X:150,784,892...150,787,438
Ensembl chr  X:150,784,841...150,787,438
JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 multiple interactions ISO [resveratrol co-treated with Streptozocin] results in decreased expression of HSD17B2 mRNA CTD PMID:25905778 NCBI chr 8:118,427,752...118,485,767
Ensembl chr 8:118,428,643...118,485,766
JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 affects expression EXP Streptozocin affects the expression of HSD17B4 mRNA CTD PMID:18583417 NCBI chr18:50,261,268...50,329,337
Ensembl chr18:50,261,268...50,329,336
JBrowse link
G Hsd3b3 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 affects expression EXP Streptozocin affects the expression of HSD3B3 mRNA CTD PMID:18583417 NCBI chr 3:98,648,792...98,672,465
Ensembl chr 3:98,648,839...98,670,443
JBrowse link
G Hsd3b5 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of HSD3B5 mRNA CTD PMID:29127188 NCBI chr 3:98,525,952...98,552,850
Ensembl chr 3:98,525,950...98,537,568
JBrowse link
G Hsd3b6 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of HSD3B6 mRNA CTD PMID:29127188 NCBI chr 3:98,712,820...98,721,759
Ensembl chr 3:98,712,820...98,721,759
JBrowse link
G Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 increases expression ISO Streptozocin results in increased expression of HSP90AA1 mRNA CTD PMID:37081038 NCBI chr12:110,657,470...110,662,829
Ensembl chr12:110,657,039...110,669,162
JBrowse link
G Hsp90b1 heat shock protein 90, beta (Grp94), member 1 multiple interactions
increases expression
EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of HSP90B1 mRNA
streptozocin increases expression of Hsp90b1 protein in heart
CTD
RGD
PMID:26522834 PMID:36044268 RGD:156430337 NCBI chr10:86,526,705...86,541,308
Ensembl chr10:86,526,073...86,541,373
JBrowse link
G Hspa2 heat shock protein 2 affects expression EXP Streptozocin affects the expression of HSPA2 mRNA CTD PMID:18583417 NCBI chr12:76,450,688...76,453,712
Ensembl chr12:76,450,950...76,453,712
JBrowse link
G Hspa5 heat shock protein 5 multiple interactions
decreases expression
increases expression
increases expression
ISO
EXP
4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of HSPA5 protein]; [Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of HSPA5 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of HSPA5 mRNA; Bilirubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of HSPA5 mRNA]; Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of HSPA5 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of HSPA5 protein]; moutan cortex inhibits the reaction [Streptozocin results in increased expression of and results in increased secretion of HSPA5 protein]; Streptozocin results in increased expression of and results in increased secretion of HSPA5 protein; Trientine inhibits the reaction [Streptozocin results in decreased expression of HSPA5 protein]; Vitamin B 12 inhibits the reaction [Streptozocin results in increased expression of HSPA5 protein]
[Dietary Fats co-treated with Streptozocin] results in increased expression of HSPA5 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of HSPA5 protein; [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of HSPA5 mRNA]; [Streptozocin co-treated with Dietary Fats] results in increased expression of HSPA5 protein; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of HSPA5 mRNA; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of HSPA5 mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of HSPA5 protein]; sulforaphane inhibits the reaction [Streptozocin results in increased expression of HSPA5 protein]
streptozocin increases expression of Hspa5 protein in heart
CTD
RGD
PMID:19634143 PMID:24967692 PMID:26522834 PMID:27664441 PMID:30980806 More... RGD:156430337 NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559
JBrowse link
G Hspa9 heat shock protein 9 decreases expression
multiple interactions
ISO Streptozocin results in decreased expression of HSPA9 protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of HSPA9 protein]
CTD PMID:19634143 NCBI chr18:35,070,467...35,087,404
Ensembl chr18:35,070,467...35,087,410
JBrowse link
G Hspb1 heat shock protein 1 multiple interactions
increases phosphorylation
ISO baicalin inhibits the reaction [Streptozocin results in increased phosphorylation of HSPB1 protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of HSPB1 protein] CTD PMID:18204486 PMID:34414639 NCBI chr 5:135,916,773...135,918,417
Ensembl chr 5:135,916,773...135,918,417
JBrowse link
G Hspd1 heat shock protein 1 (chaperonin) multiple interactions
increases expression
decreases expression
ISO Trientine inhibits the reaction [Streptozocin results in decreased expression of HSPD1 protein]; Trientine inhibits the reaction [Streptozocin results in increased expression of HSPD1 protein] CTD PMID:19634143 PMID:21136691 NCBI chr 1:55,116,992...55,127,402
Ensembl chr 1:55,116,994...55,127,402
JBrowse link
G Hspe1 heat shock protein 1 (chaperonin 10) multiple interactions
decreases expression
ISO Trientine inhibits the reaction [Streptozocin results in decreased expression of HSPE1 protein] CTD PMID:19634143 NCBI chr 1:55,127,307...55,130,476
Ensembl chr 1:55,127,291...55,130,466
JBrowse link
G Hspg2 perlecan (heparan sulfate proteoglycan 2) increases expression
multiple interactions
ISO Streptozocin results in increased expression of HSPG2 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of HSPG2 protein]
CTD PMID:19634143 NCBI chr 4:137,196,062...137,297,941
Ensembl chr 4:137,196,080...137,297,941
JBrowse link
G Htr1a 5-hydroxytryptamine (serotonin) receptor 1A multiple interactions ISO Streptozocin inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased activity of HTR1A protein] CTD PMID:18622176 NCBI chr13:105,580,040...105,584,630
Ensembl chr13:105,580,147...105,584,630
JBrowse link
G Htr2a 5-hydroxytryptamine (serotonin) receptor 2A multiple interactions ISO Streptozocin inhibits the reaction [4-iodo-2,5-dimethoxyphenylisopropylamine results in increased activity of HTR2A protein] CTD PMID:18622176 NCBI chr14:74,878,314...74,944,299
Ensembl chr14:74,878,280...74,946,934
JBrowse link
G Htr2c 5-hydroxytryptamine (serotonin) receptor 2C multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of HTR2C mRNA CTD PMID:33484791 NCBI chr  X:145,745,509...145,980,273
Ensembl chr  X:145,745,509...145,980,273
JBrowse link
G Iapp islet amyloid polypeptide multiple interactions
decreases expression
ISO
EXP
rosiglitazone inhibits the reaction [Streptozocin results in decreased expression of IAPP mRNA]
[octylphenol co-treated with Streptozocin] results in decreased expression of IAPP mRNA; Streptozocin inhibits the reaction [Ethinyl Estradiol results in decreased expression of IAPP mRNA]
CTD PMID:18998217 PMID:29935216 NCBI chr 6:142,244,151...142,249,546
Ensembl chr 6:142,244,149...142,249,687
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
increases expression
EXP
ISO
AM6545 inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; AM6545 inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]]; Clodronic Acid inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; Curcumin analog inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; dehydroxymethylepoxyquinomicin inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; dehydroxymethylepoxyquinomicin inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; Perindopril inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; Perindopril inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; sulforaphane inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; Telmisartan inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]
Streptozocin results in increased expression of ICAM1 mRNA; Streptozocin results in increased expression of ICAM1 protein
[Streptozocin co-treated with Cholesterol, Dietary] results in increased expression of ICAM1 protein; Atorvastatin inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; Atorvastatin inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; candesartan inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; cloricromen inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; fasudil inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Cholesterol, Dietary] results in increased expression of ICAM1 protein]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; moutan cortex inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; Rosiglitazone inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; Rosiglitazone inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]
CTD PMID:10485912 PMID:14871415 PMID:15892581 PMID:16129698 PMID:16139267 More... NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113
JBrowse link
G Id2 inhibitor of DNA binding 2 decreases expression ISO Streptozocin results in decreased expression of ID2 mRNA CTD PMID:25905778 NCBI chr12:25,143,798...25,146,091
Ensembl chr12:25,143,798...25,147,139
JBrowse link
G Idh2 isocitrate dehydrogenase 2 (NADP+), mitochondrial affects expression EXP Streptozocin affects the expression of IDH2 mRNA CTD PMID:18583417 NCBI chr 7:79,744,594...79,768,356
Ensembl chr 7:79,744,594...79,765,140
JBrowse link
G Ifitm3 interferon induced transmembrane protein 3 multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of IFITM3 mRNA CTD PMID:25905778 NCBI chr 7:140,589,503...140,590,657
Ensembl chr 7:140,589,499...140,590,683
JBrowse link
G Ifng interferon gamma multiple interactions
increases expression
decreases expression
EXP
ISO
Clodronic Acid inhibits the reaction [Streptozocin results in increased expression of IFNG protein]; Dronabinol inhibits the reaction [Streptozocin results in increased expression of IFNG mRNA]; S-Nitroso-N-Acetylpenicillamine inhibits the reaction [Streptozocin results in increased expression of IFNG protein]; Sodium Selenite inhibits the reaction [Streptozocin results in increased expression of IFNG mRNA]
Streptozocin results in increased expression of IFNG mRNA; Streptozocin results in increased expression of IFNG protein
arjunolic acid inhibits the reaction [Streptozocin results in decreased expression of IFNG protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of IFNG protein]
CTD PMID:11357882 PMID:15862027 PMID:15892581 PMID:15975818 PMID:18789669 More... NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
JBrowse link
G Igdcc4 immunoglobulin superfamily, DCC subclass, member 4 multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of IGDCC4 mRNA CTD PMID:33484791 NCBI chr 9:65,008,246...65,045,225
Ensembl chr 9:65,008,768...65,045,222
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions
decreases expression
increases expression
EXP
ISO
[Dietary Fats co-treated with Streptozocin] results in increased expression of IGF1 mRNA; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IGF1 mRNA]; IGF1 protein inhibits the reaction [Streptozocin results in increased expression of AGT protein]; IGF1 protein inhibits the reaction [Streptozocin results in increased expression of BAX protein]; IGF1 protein inhibits the reaction [Streptozocin results in increased expression of TRP53 protein]; Metformin inhibits the reaction [Streptozocin results in decreased expression of IGF1 protein]; puerarin inhibits the reaction [Streptozocin results in decreased expression of IGF1 protein]
Streptozocin results in decreased expression of IGF1 mRNA; Streptozocin results in decreased expression of IGF1 protein
Streptozocin results in increased expression of IGF1 protein
[Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IGF1 protein]; [Streptozocin co-treated with Dietary Fats] results in increased expression of IGF1 protein; Dimethyl Fumarate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IGF1 protein]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IGF1 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IGF1 protein]; Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of IGF1 protein]; Rivastigmine inhibits the reaction [Streptozocin results in decreased expression of IGF1 protein]; Wortmannin inhibits the reaction [Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of IGF1 protein]]
CTD PMID:7637645 PMID:9868179 PMID:11375343 PMID:23927877 PMID:25617479 More... NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904
JBrowse link
G Igf1r insulin-like growth factor I receptor decreases expression
multiple interactions
ISO
EXP
Streptozocin results in decreased expression of IGF1R protein
[Dietary Fats co-treated with Streptozocin co-treated with Ovalbumin] results in decreased expression of IGF1R mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Ovalbumin] results in decreased expression of IGF1R protein; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin co-treated with Ovalbumin] results in decreased expression of IGF1R mRNA]; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin co-treated with Ovalbumin] results in decreased expression of IGF1R protein]; xanthoceraside inhibits the reaction [Streptozocin results in decreased expression of IGF1R protein]
[Streptozocin co-treated with CNR1 protein] affects the expression of IGF1R protein
CTD PMID:23562514 PMID:30721768 PMID:36547818 NCBI chr 7:67,601,486...67,883,416
Ensembl chr 7:67,602,575...67,883,416
JBrowse link
G Igf2bp3 insulin-like growth factor 2 mRNA binding protein 3 multiple interactions ISO [resveratrol co-treated with Streptozocin] results in decreased expression of IGF2BP3 mRNA CTD PMID:25905778 NCBI chr 6:49,062,152...49,200,225
Ensembl chr 6:49,062,157...49,191,891
JBrowse link
G Igf2r insulin-like growth factor 2 receptor multiple interactions
increases expression
increases response to substance
ISO [IGF2R protein alternative form results in increased susceptibility to Streptozocin] which results in increased abundance of Cholesterol; [IGF2R protein alternative form results in increased susceptibility to Streptozocin] which results in increased abundance of Triglycerides; [Streptozocin co-treated with IGF2R protein modified form] results in increased expression of CASP3 protein modified form; IGF2R protein modified form inhibits the reaction [Streptozocin results in increased expression of CASP9 protein]; IGF2R protein modified form promotes the reaction [Streptozocin results in decreased expression of BCL2 protein]; IGF2R protein modified form promotes the reaction [Streptozocin results in decreased expression of NFKBIA protein modified form]; IGF2R protein modified form promotes the reaction [Streptozocin results in increased expression of IL1B protein]; IGF2R protein modified form promotes the reaction [Streptozocin results in increased expression of PTGS2 protein]; IGF2R protein modified form promotes the reaction [Streptozocin results in increased expression of RELA protein modified form]; IGF2R protein modified form promotes the reaction [Streptozocin results in increased expression of TNF protein]; Streptozocin promotes the reaction [IGF2R protein alternative form results in increased abundance of Triglycerides]; Streptozocin promotes the reaction [IGF2R protein modified form results in decreased expression of BCL2 protein modified form]; Streptozocin promotes the reaction [IGF2R protein modified form results in decreased expression of NFKBIA protein modified form]; Streptozocin promotes the reaction [IGF2R protein modified form results in increased expression of IL6 protein]; Streptozocin promotes the reaction [IGF2R protein modified form results in increased expression of RELA protein modified form]
Streptozocin results in increased expression of IGF2R protein
CTD PMID:35993117 PMID:36462176 NCBI chr17:12,901,293...12,988,593
Ensembl chr17:12,901,293...12,988,551
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 multiple interactions EXP [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of IGFBP1 mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of IGFBP1 protein; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of IGFBP1 mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of IGFBP1 protein] CTD PMID:39047806 NCBI chr11:7,147,787...7,152,546
Ensembl chr11:7,147,782...7,152,546
JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of IGFBP2 mRNA CTD PMID:25905778 NCBI chr 1:72,863,650...72,891,633
Ensembl chr 1:72,863,662...72,891,633
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 increases expression
multiple interactions
EXP Streptozocin results in increased expression of IGFBP3 mRNA
2-amino-6-boronohexanoic acid inhibits the reaction [Streptozocin results in increased expression of IGFBP3 mRNA]
CTD PMID:29673160 NCBI chr11:7,156,086...7,165,498
Ensembl chr11:7,156,086...7,163,923
JBrowse link
G Igfbp7 insulin-like growth factor binding protein 7 increases expression EXP Streptozocin results in increased expression of IGFBP7 mRNA CTD PMID:29673160 NCBI chr 5:77,497,092...77,555,892
Ensembl chr 5:77,497,087...77,555,888
JBrowse link
G Igsf6 immunoglobulin superfamily, member 6 multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of IGSF6 mRNA CTD PMID:25905778 NCBI chr 7:120,663,290...120,673,753
Ensembl chr 7:120,663,290...120,673,795
JBrowse link
G Ikbkb inhibitor of kappaB kinase beta multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of IKBKB protein; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of IKBKB protein] CTD PMID:34610774 NCBI chr 8:23,149,228...23,196,605
Ensembl chr 8:23,149,228...23,196,605
JBrowse link
G Il10 interleukin 10 decreases expression
multiple interactions
increases expression
EXP
ISO
Streptozocin results in decreased expression of IL10 mRNA
[Streptozocin co-treated with Dietary Fats] results in decreased expression of IL10 protein; [Streptozocin co-treated with Sodium Glutamate] results in increased expression of IL10 protein; [Vanadium co-treated with Selenium co-treated with Vitamin E co-treated with Chromium] inhibits the reaction [Streptozocin results in decreased expression of IL10 protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of IL10 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of IL10 protein]; Metformin inhibits the reaction [Streptozocin results in decreased expression of IL10 protein]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of IL10 mRNA]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of IL10 protein]
Streptozocin results in decreased expression of IL10 mRNA; Streptozocin results in decreased expression of IL10 protein
Streptozocin results in increased expression of IL10 mRNA
2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of IL10 mRNA]; 2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of IL10 protein]; [Streptozocin co-treated with Niacinamide] results in decreased expression of IL10 mRNA; [Streptozocin co-treated with Niacinamide] results in decreased expression of IL10 protein; Chlorpyrifos inhibits the reaction [Streptozocin results in increased expression of IL10 mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of IL10 mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of IL10 protein]
Streptozocin results in increased expression of IL10 protein
CTD PMID:15862027 PMID:32662907 PMID:33524429 PMID:33639173 PMID:35085591 More... NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
JBrowse link
G Il12b interleukin 12b increases expression
multiple interactions
EXP Streptozocin results in increased expression of IL12B mRNA
Dronabinol inhibits the reaction [Streptozocin results in increased expression of IL12B mRNA]
CTD PMID:11357882 NCBI chr11:44,290,890...44,305,504
Ensembl chr11:44,290,890...44,304,860
JBrowse link
G Il17a interleukin 17A multiple interactions
increases expression
ISO stannous mesoporphyrin inhibits the reaction [4-(4-(3-adamantan-1-ylureido)cyclohexyloxy)benzoic acid inhibits the reaction [Streptozocin results in increased expression of IL17A protein]] CTD PMID:23611540 NCBI chr 1:20,801,129...20,804,720
Ensembl chr 1:20,801,129...20,804,720
JBrowse link
G Il18 interleukin 18 multiple interactions
increases expression
ISO
EXP
[Streptozocin co-treated with Niacinamide co-treated with ENV-2 compound] results in decreased expression of IL18 mRNA; Allopurinol inhibits the reaction [Streptozocin results in increased expression of IL18 protein]; nifuroxazide inhibits the reaction [Streptozocin results in increased expression of IL18 mRNA]; palbinone inhibits the reaction [Streptozocin results in increased expression of IL18 protein]; Quercetin inhibits the reaction [Streptozocin results in increased expression of IL18 protein]; scutellarin inhibits the reaction [Streptozocin results in increased expression of IL18 protein]
Streptozocin results in increased expression of IL18 mRNA; Streptozocin results in increased expression of IL18 protein
[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of IL18 protein; [Dietary Fats co-treated with Streptozocin] results in increased expression of IL18 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of IL18 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of IL18 protein; aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL18 protein]; GSDMD protein affects the reaction [Streptozocin results in increased expression of IL18 protein]; Hirudins inhibits the reaction [Streptozocin results in increased expression of IL18 protein]; loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of IL18 protein]; loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL18 mRNA]
CTD PMID:23647015 PMID:28322830 PMID:29291386 PMID:32202043 PMID:34212273 More... NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140
JBrowse link
G Il1a interleukin 1 alpha multiple interactions EXP [Streptozocin co-treated with bisphenol A] results in increased expression of IL1A mRNA; [Streptozocin co-treated with Ethinyl Estradiol] results in increased expression of IL1A mRNA; [Streptozocin co-treated with octylphenol] results in increased expression of IL1A mRNA CTD PMID:24781736 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
decreases expression
ISO
EXP
PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]
[Chlorpyrifos co-treated with Streptozocin] results in increased expression of IL1B mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of IL1B protein; [Streptozocin co-treated with Dextran Sulfate] results in increased expression of IL1B protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B protein; [Streptozocin co-treated with Dietary Fats] results in increased secretion of IL1B protein; Acrylamide inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; Alendronate inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Ascorbic Acid inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; asiatic acid inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; asiatic acid promotes the reaction [Carnosine inhibits the reaction [Streptozocin results in increased expression of IL1B protein]]; aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B mRNA]; aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B protein]; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased secretion of IL1B protein]; Carnosine inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Donepezil inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Genistein inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; GSDMD protein affects the reaction [Streptozocin results in increased expression of IL1B protein]; Hirudins inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of IL1B protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; montelukast inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Sodium Selenite inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]
Streptozocin results in increased expression of IL1B mRNA; Streptozocin results in increased expression of IL1B protein
7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL1B protein]; [Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in increased expression of IL1B protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of IL1B protein; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of IL1B protein; [Niacinamide co-treated with Streptozocin] results in increased expression of IL1B protein; [pimagedine co-treated with Fatty Acids, Omega-3] inhibits the reaction [Streptozocin results in increased expression of and results in increased secretion of IL1B protein]; [Resveratrol co-treated with Streptozocin] results in increased expression of IL1B mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B protein; [Streptozocin co-treated with Niacinamide co-treated with ENV-2 compound] results in decreased expression of IL1B mRNA; [Streptozocin co-treated with Niacinamide] results in increased expression of IL1B protein; [Streptozocin co-treated with Sodium Glutamate] results in increased expression of IL1B protein; Allopurinol inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Atorvastatin inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of IL1B protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of IL1B protein]; Diosgenin inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; Diosgenin inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of IL1B protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B protein]; Enalapril inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; Gallic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B protein]; Gliclazide inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in increased expression of IL1B protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of IL1B protein]; Gliclazide inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of IL1B protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; Glyburide inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; IGF2R protein modified form promotes the reaction [Streptozocin results in increased expression of IL1B protein]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B protein]; Metformin inhibits the reaction [Streptozocin results in decreased expression of IL1B protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in increased expression of IL1B protein]]; myrtenol inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; palbinone inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Pentoxifylline inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; pinitol inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Plant Extracts inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Resveratrol inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in increased expression of IL1B protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of IL1B protein]; Streptozocin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of IL1B mRNA]; Streptozocin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of IL1B protein]; Streptozocin results in increased expression of and results in increased secretion of IL1B protein; STUB1 inhibits the reaction [Streptozocin results in increased phosphorylation of IL1B protein]; sulbutiamine inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Tropisetron inhibits the reaction [Streptozocin results in increased expression of IL1B protein]
CTD PMID:12123627 PMID:16129698 PMID:17167242 PMID:17589825 PMID:18789669 More... NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 multiple interactions ISO 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL1RL1 mRNA]; [Dietary Fats co-treated with Streptozocin] results in increased expression of IL1RL1 mRNA CTD PMID:31726037 NCBI chr 1:40,444,105...40,504,575
Ensembl chr 1:40,468,730...40,504,575
JBrowse link
G Il1rn interleukin 1 receptor antagonist multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of IL1RN mRNA CTD PMID:29127188 NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506
JBrowse link
G Il2 interleukin 2 multiple interactions
decreases expression
ISO arjunolic acid inhibits the reaction [Streptozocin results in decreased expression of IL2 protein] CTD PMID:20053369 NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108
JBrowse link
G Il22b interleukin 22B multiple interactions EXP IL22 protein inhibits the reaction [Streptozocin results in increased abundance of Glucose] CTD PMID:26064446 NCBI chr10:118,125,534...118,130,943
Ensembl chr10:118,125,534...118,130,943
JBrowse link
G Il23a interleukin 23, alpha subunit p19 multiple interactions
increases expression
EXP 5-Methoxypsoralen inhibits the reaction [Streptozocin results in increased expression of IL23A protein]; Tadalafil inhibits the reaction [Streptozocin results in increased expression of IL23A protein] CTD PMID:34428446 NCBI chr10:128,132,009...128,133,953
Ensembl chr10:128,132,008...128,134,621
JBrowse link
G Il27 interleukin 27 multiple interactions
increases expression
EXP 5-Methoxypsoralen inhibits the reaction [Streptozocin results in increased expression of IL27 protein]; Tadalafil inhibits the reaction [Streptozocin results in increased expression of IL27 protein] CTD PMID:34428446 NCBI chr 7:126,188,181...126,194,197
Ensembl chr 7:126,188,182...126,194,113
JBrowse link
G Il33 interleukin 33 multiple interactions ISO 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL33 mRNA]; 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL33 protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of IL33 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of IL33 protein CTD PMID:31726037 NCBI chr19:29,902,513...29,938,118
Ensembl chr19:29,902,514...29,938,118
JBrowse link
G Il4 interleukin 4 multiple interactions
decreases expression
ISO resveratrol inhibits the reaction [Streptozocin results in decreased expression of IL4] CTD PMID:25191525 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
JBrowse link
G Il6 interleukin 6 increases expression
increases secretion
multiple interactions
decreases expression
ISO
EXP
Streptozocin results in increased expression of IL6 mRNA; Streptozocin results in increased expression of IL6 protein
Streptozocin results in increased secretion of IL6 protein
3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; 4-methyl-2-((2-methylbenzyl) amino)-1,3-thiazole-5-carboxylic acid inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL6 protein]; 7-hydroxycoumarin inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; [Dietary Fats co-treated with Streptozocin co-treated with Plant Extracts] affects the expression of IL6 protein; [Dietary Fats co-treated with Streptozocin co-treated with Quercetin] affects the expression of IL6 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Quercetin] affects the expression of IL6 protein; [Dietary Fats co-treated with Streptozocin] results in increased expression of IL6 protein; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of IL6 protein; [Niacinamide co-treated with Streptozocin] results in increased expression of IL6 protein; [Propolis co-treated with Streptozocin co-treated with Chlorpyrifos] results in increased secretion of IL6 protein; [Propolis co-treated with Streptozocin] results in increased secretion of IL6 protein; [Streptozocin co-treated with Chlorpyrifos] results in increased secretion of IL6 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of IL6 protein; [Streptozocin co-treated with Niacinamide] results in increased expression of IL6 protein; [Streptozocin co-treated with Sodium Glutamate] results in increased expression of IL6 protein; Acetylcysteine inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Allopurinol inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of IL6 protein]; caryophyllene inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; crocin inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Diosgenin inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; Diosgenin inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Dronabinol inhibits the reaction [Streptozocin results in decreased expression of IL6 protein]; Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL6 protein]; Enalapril inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; Flavonoids inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Gallic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL6 protein]; Gliclazide inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in increased expression of IL6 protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of IL6 protein]; Gliclazide inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of IL6 protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; Glyburide inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; hesperetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL6 protein]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; mangiferin inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Melatonin inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL6 protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; Metformin inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; moutan cortex inhibits the reaction [Streptozocin results in increased expression of and results in increased secretion of IL6 protein]; Pentoxifylline inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; pinitol inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; piperlongumine inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; piperlongumine inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Plant Extracts inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL6 protein]; Propolis inhibits the reaction [[Streptozocin co-treated with Chlorpyrifos] results in increased secretion of IL6 protein]; Propolis inhibits the reaction [Streptozocin results in increased secretion of IL6 protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL6 protein]; Resveratrol inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in increased expression of IL6 protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of IL6 protein]; SMe1EC2 promotes the reaction [Streptozocin results in increased expression of IL6 protein]; Streptozocin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of IL6 mRNA]; Streptozocin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of IL6 protein]; Streptozocin promotes the reaction [IGF2R protein modified form results in increased expression of IL6 protein]; Streptozocin results in increased expression of and results in increased secretion of IL6 protein
3-((6-(2-methoxyphenyl)pyrimidin-4-yl)amino)phenyl)methane sulfonamide inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; [Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of IL6 protein; [Dietary Fats co-treated with Streptozocin] results in increased expression of IL6 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of IL6 protein; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of IL6 mRNA; [Streptozocin co-treated with Dextran Sulfate] results in increased expression of IL6 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of IL6 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased secretion of IL6 protein; Acrylamide inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; Alendronate inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; asiatic acid inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; asiatic acid promotes the reaction [Carnosine inhibits the reaction [Streptozocin results in increased expression of IL6 protein]]; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased secretion of IL6 protein]; Carnosine inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Carnosine promotes the reaction [asiatic acid inhibits the reaction [Streptozocin results in increased expression of IL6 protein]]; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Curcumin analog inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; Donepezil inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; esculetin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL6 mRNA]; esculetin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL6 protein]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of IL6 protein]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of IL6 mRNA]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL6 mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of IL6 protein]
CTD PMID:17167242 PMID:17854708 PMID:18999900 PMID:20307516 PMID:20643114 More... NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Il6st interleukin 6 signal transducer affects expression EXP Streptozocin affects the expression of IL6ST mRNA CTD PMID:26073000 NCBI chr13:112,600,604...112,643,394
Ensembl chr13:112,600,604...112,646,620
JBrowse link
G Ilk integrin linked kinase multiple interactions
increases activity
ISO notoginsenoside R1 inhibits the reaction [Streptozocin results in increased activity of ILK protein] CTD PMID:25503068 NCBI chr 7:105,385,797...105,392,132
Ensembl chr 7:105,385,799...105,392,132
JBrowse link
G Impa2 inositol monophosphatase 2 increases expression
multiple interactions
ISO Streptozocin results in increased expression of IMPA2 mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of IMPA2 mRNA]
CTD PMID:16684804 NCBI chr18:67,422,246...67,454,375
Ensembl chr18:67,422,256...67,455,542
JBrowse link
G Inava innate immunity activator multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of INAVA mRNA CTD PMID:33484791 NCBI chr 1:136,141,259...136,162,045
Ensembl chr 1:136,141,269...136,162,002
JBrowse link
G Inhbb inhibin beta-B multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of INHBB mRNA CTD PMID:29127188 NCBI chr 1:119,343,193...119,349,978
Ensembl chr 1:119,343,195...119,349,978
JBrowse link
G Inpp5k inositol polyphosphate 5-phosphatase K multiple interactions EXP [Dietary Fats co-treated with Streptozocin] results in increased expression of INPP5K mRNA; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of INPP5K mRNA] CTD PMID:33812996 NCBI chr11:75,519,893...75,539,691
Ensembl chr11:75,521,814...75,539,697
JBrowse link
G Ins1 insulin I multiple interactions
decreases expression
decreases secretion
increases secretion
decreases response to substance
increases expression
EXP
ISO
[1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of and results in decreased secretion of INS1 protein]; [Carnosine co-treated with asiatic acid] inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of and results in decreased secretion of INS1 protein; [Dietary Fats co-treated with Streptozocin] results in decreased expression of INS1 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of INS1 protein; [Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of INS1 protein; [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of INS1 protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of INS1 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of INS1 protein; [Streptozocin co-treated with INS1 protein co-treated with Glutathione] affects the expression of CAT mRNA; [Streptozocin co-treated with INS1 protein co-treated with Glutathione] affects the expression of SOD2 mRNA; AM 251 inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; asiatic acid inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; bisphenol A inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; Carnosine inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; CNR1 protein promotes the reaction [Streptozocin results in decreased expression of INS1 protein]; Dronabinol inhibits the reaction [Streptozocin results in decreased expression of INS1]; Edaravone inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; Ethinyl Estradiol inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of INS1 mRNA]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of INS1 protein]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of INS1 protein]; Glyburide inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; INS1 inhibits the reaction [[Streptozocin co-treated with APOE mutant form] results in increased abundance of Glucosamine]; INS1 protein affects the reaction [Streptozocin results in decreased methylation of PPP2CA protein]; INS1 protein inhibits the reaction [Streptozocin results in decreased expression of DNMT1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of POU1F1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of POU1F1 protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of SLC20A2 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of SLC20A2 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of INS1 protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; octylphenol inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; PQQ Cofactor inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; pterostilbene inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of INS1 protein]; Streptozocin inhibits the reaction [Glucose results in increased secretion of INS1 protein]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of INS1 protein]
Streptozocin results in decreased expression of INS1; Streptozocin results in decreased expression of INS1 protein
Streptozocin results in increased secretion of INS1 protein
Streptozocin results in decreased expression of INS1 protein; Streptozocin results in decreased expression of INS1 protein modified form
ALPK1 protein promotes the reaction [Streptozocin results in decreased secretion of INS1 protein]
Streptozocin results in decreased susceptibility to INS1 protein
Streptozocin results in increased expression of INS1 mRNA; Streptozocin results in increased expression of INS1 protein
4-hydroxyisoleucine inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; 4-hydroxyphenylethanol inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; 4-methyl-2-((2-methylbenzyl) amino)-1,3-thiazole-5-carboxylic acid inhibits the reaction [Streptozocin results in increased expression of INS1 protein]; 7-hydroxycoumarin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of INS1 protein; [Dietary Fats co-treated with Streptozocin] results in decreased secretion of INS1 protein; [Dietary Fats co-treated with Streptozocin] results in increased secretion of INS1 protein; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of INS1 protein; [INS1 protein co-treated with Pravastatin] inhibits the reaction [Streptozocin results in decreased expression of ACE2 protein]; [INS1 protein co-treated with Pravastatin] inhibits the reaction [Streptozocin results in increased expression of ACE protein]; [Niacinamide co-treated with Streptozocin] results in decreased expression of INS1 protein; [Plant Extracts co-treated with glimepiride] inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; [Propolis co-treated with Chlorpyrifos] inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; [Propolis co-treated with Streptozocin co-treated with Chlorpyrifos] results in decreased secretion of INS1 protein; [Propolis co-treated with Streptozocin] promotes the reaction [Chlorpyrifos results in decreased expression of INS1 protein]; [Propolis co-treated with Streptozocin] promotes the reaction [Chlorpyrifos results in decreased secretion of INS1 protein]; [Propolis co-treated with Streptozocin] results in decreased secretion of INS1 protein; [Streptozocin co-treated with Cadmium] results in decreased expression of INS1 protein; [Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in increased expression of INS1 protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of INS1 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of INS1 protein; [Streptozocin co-treated with Fructose] results in increased expression of INS1 protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of INS1 protein; [Streptozocin co-treated with Niacinamide] results in decreased secretion of INS1 protein; [Streptozocin co-treated with Niacinamide] results in increased expression of INS1 protein; [Streptozocin co-treated with Sodium Glutamate] results in decreased expression of INS1 protein; Acetates inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of INS1 protein]; allyl isothiocyanate inhibits the reaction [Streptozocin promotes the reaction [Dietary Fats results in increased expression of INS1 protein]]; anthranilic acid analog inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; asiatic acid inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; baicalin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of INS1 protein]; Butyric Acid inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; carvacrol affects the reaction [Streptozocin results in decreased expression of INS1 protein]; caryophyllene inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; chebulagic acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of INS1 protein]; Chlorpyrifos inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; citronellol inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; corilagin inhibits the reaction [Streptozocin results in increased secretion of INS1 protein]; costunolide inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; coumarin inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in decreased expression of INS1 protein]; coumarin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of INS1 protein]; crocin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; Diosgenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of INS1 protein]; Diosgenin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; Estradiol inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; eupafolin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of INS1 protein]; Ficusin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of INS1 protein]; geraniol inhibits the reaction [Streptozocin results in decreased expression of and results in decreased secretion of INS1 protein]; Gliclazide inhibits the reaction [Streptozocin results in decreased expression of and results in decreased secretion of INS1 protein]; Gliclazide inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; glimepiride inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of INS1 protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of INS1 protein]; Glyburide inhibits the reaction [Streptozocin results in increased secretion of INS1 protein]; Imatinib Mesylate inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; INS1 protein inhibits the reaction [Streptozocin results in decreased expression of GAD1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in decreased expression of GPX1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in decreased expression of SLC1A3 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased activity of CAT protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of CASP8 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of COL3A1 protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of CYP8B1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of GRIA4 protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of GRIN1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of GRIN1 protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of MMP2 protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of MMP9 protein]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of INS1 protein]; Lithium Carbonate inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; mangiferin inhibits the reaction [Streptozocin results in increased expression of INS1 protein]; Melatonin affects the reaction [Streptozocin results in decreased expression of INS1 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in increased expression of INS1 protein]; Metformin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; morin analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of INS1 protein]; morin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased expression of INS1 protein]; myrtenal inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; nerolidol inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of INS1 protein]; palbinone inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; Phosphocreatine inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; Pioglitazone inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of INS1 protein]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of INS1 protein]; Plant Extracts inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased secretion of INS1 protein]; Plant Extracts inhibits the reaction [[Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in increased expression of INS1 protein]; Plant Extracts inhibits the reaction [Streptozocin results in decreased expression of and results in decreased secretion of INS1 protein]; Plant Extracts inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; Plant Extracts inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; plumbagin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; Polysaccharides inhibits the reaction [Streptozocin results in decreased expression of and results in decreased secretion of INS1 protein]; Propolis inhibits the reaction [[Streptozocin co-treated with Chlorpyrifos] results in decreased secretion of INS1 protein]; Propolis inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of INS1 protein]; repaglinide analog affects the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of INS1 protein]; repaglinide inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of INS1 protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of INS1 protein]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; Rosiglitazone promotes the reaction [Streptozocin inhibits the reaction [Dietary Fats results in increased expression of INS1 protein]]; S-allylcysteine inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; Streptozocin affects the reaction [Chlorpyrifos results in decreased secretion of INS1 protein]; Streptozocin inhibits the reaction [Blood Glucose results in increased secretion of INS1 protein]; Streptozocin inhibits the reaction [Dietary Fats results in increased expression of INS1 protein]; Streptozocin promotes the reaction [Dietary Fats results in increased expression of INS1 protein]; Streptozocin results in decreased expression of and results in decreased secretion of INS1 protein; thymoquinone inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of INS1 protein]; thymoquinone inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased secretion of INS1 protein]; TRH protein inhibits the reaction [Streptozocin inhibits the reaction [Blood Glucose results in increased secretion of INS1 protein]]; Tribulus extract inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; Warfarin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased secretion of INS1 protein]; Zinc Compounds inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of INS1 protein]
CTD PMID:6337899 PMID:7564366 PMID:9868179 PMID:10393316 PMID:10700396 More... NCBI chr19:52,252,735...52,253,453
Ensembl chr19:52,252,735...52,253,914
JBrowse link
G Ins2 insulin II multiple interactions
decreases expression
ISO
EXP
INS protein inhibits the reaction [Streptozocin results in decreased expression of NES mRNA]; Resveratrol inhibits the reaction [Streptozocin inhibits the reaction [INS protein results in increased phosphorylation of INSR protein]]; Streptozocin inhibits the reaction [INS protein results in increased phosphorylation of INSR protein]
[Dietary Fats co-treated with Streptozocin] results in decreased expression of INS2 mRNA; [Diethylhexyl Phthalate co-treated with Streptozocin co-treated with Dietary Fats] results in increased expression of INS2 mRNA; [Glyburide co-treated with Streptozocin] results in increased secretion of INS protein; [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of INS2 protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of INS2 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of INS2 mRNA]; INS protein inhibits the reaction [Streptozocin results in decreased activity of SOD3 protein]; INS protein inhibits the reaction [Streptozocin results in decreased expression of ATP7A protein]
Streptozocin results in decreased expression of INS protein
[Berberine co-treated with Streptozocin] results in increased secretion of INS protein; INS protein inhibits the reaction [Streptozocin results in decreased expression of FASN mRNA]; INS protein inhibits the reaction [Streptozocin results in decreased expression of POMC mRNA]; INS protein inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]; INS protein inhibits the reaction [Streptozocin results in increased expression of AGRP mRNA]; INS protein inhibits the reaction [Streptozocin results in increased expression of NPY mRNA]; INS protein promotes the reaction [Streptozocin results in decreased activity of SOD2 protein]; INS protein promotes the reaction [Streptozocin results in increased activity of GSR protein]; INS protein promotes the reaction [Streptozocin results in increased expression of PPARG mRNA]
CTD PMID:11216864 PMID:15066220 PMID:19388005 PMID:20219977 PMID:22940631 More... NCBI chr 7:142,232,393...142,233,463
Ensembl chr 7:142,232,393...142,297,118
JBrowse link
G Insig1 insulin induced gene 1 multiple interactions EXP [Dietary Fats co-treated with Streptozocin] results in increased expression of INSIG1 mRNA CTD PMID:33359794 NCBI chr 5:28,276,410...28,283,660
Ensembl chr 5:28,276,361...28,283,660
JBrowse link
G Insig2 insulin induced gene 2 decreases expression ISO Streptozocin results in decreased expression of INSIG2 mRNA CTD PMID:25905778 NCBI chr 1:121,232,082...121,260,391
Ensembl chr 1:121,232,082...121,260,318
JBrowse link
G Insr insulin receptor affects expression
decreases expression
decreases phosphorylation
increases expression
multiple interactions
increases expression
ISO
EXP
Streptozocin affects the expression of INSR protein
Streptozocin results in decreased expression of INSR mRNA; Streptozocin results in decreased expression of INSR protein
Streptozocin results in decreased phosphorylation of INSR protein
Streptozocin results in increased expression of INSR mRNA
[1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of INSR protein]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of INSR mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of INSR protein; [Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of INSR protein; Metformin inhibits the reaction [Streptozocin results in decreased expression of INSR mRNA]; puerarin inhibits the reaction [Streptozocin results in decreased expression of INSR mRNA]
resveratrol inhibits the reaction [Streptozocin inhibits the reaction [INS protein results in increased phosphorylation of INSR protein]]; Streptozocin inhibits the reaction [INS protein results in increased phosphorylation of INSR protein]
[Dietary Fats co-treated with Streptozocin co-treated with Ovalbumin] results in decreased expression of INSR mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Ovalbumin] results in decreased expression of INSR protein; [Dietary Fats co-treated with Streptozocin co-treated with Quercetin] affects the expression of INSR mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of INSR mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of INSR protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of INSR protein; asiatic acid inhibits the reaction [Streptozocin results in decreased expression of INSR protein]; Estradiol affects the reaction [Streptozocin affects the expression of INSR protein]; eupafolin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of INSR protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of INSR protein]; Melatonin inhibits the reaction [Streptozocin results in decreased expression of INSR protein]; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin co-treated with Ovalbumin] results in decreased expression of INSR mRNA]; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin co-treated with Ovalbumin] results in decreased expression of INSR protein]; Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of INSR mRNA]; Plant Extracts inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of INSR mRNA]; Plant Extracts inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of INSR protein]; Progesterone affects the reaction [Streptozocin affects the expression of INSR protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of INSR protein]; Rivastigmine inhibits the reaction [Streptozocin results in decreased expression of INSR mRNA]; Wortmannin inhibits the reaction [Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of INSR mRNA]]; xanthoceraside inhibits the reaction [Streptozocin results in decreased expression of INSR protein]
streptozocin increases expression of hepatic mRNA
CTD
RGD
PMID:9243097 PMID:17068109 PMID:18331706 PMID:19705549 PMID:21439094 More... RGD:15036814 NCBI chr 8:3,200,922...3,329,649
Ensembl chr 8:3,172,061...3,329,617
JBrowse link
G Insrr insulin receptor-related receptor multiple interactions EXP [Dietary Fats co-treated with Streptozocin] results in decreased expression of INSRR mRNA; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of INSRR mRNA] CTD PMID:33359794 NCBI chr 3:87,704,215...87,723,408
Ensembl chr 3:87,704,258...87,723,408
JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 increases expression
multiple interactions
ISO Streptozocin results in increased expression of IRAK1 protein
Glyburide inhibits the reaction [Streptozocin results in increased expression of IRAK1 protein]; Tropisetron inhibits the reaction [Streptozocin results in increased expression of IRAK1 protein]
CTD PMID:36504472 NCBI chr  X:73,057,520...73,067,527
Ensembl chr  X:73,057,520...73,067,524
JBrowse link
G Irf1 interferon regulatory factor 1 multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of IRF1 mRNA CTD PMID:25905778 NCBI chr11:53,660,841...53,669,200
Ensembl chr11:53,660,841...53,669,200
JBrowse link
G Irf2 interferon regulatory factor 2 increases expression
multiple interactions
EXP Streptozocin results in increased expression of IRF2 mRNA
Hirudins inhibits the reaction [Streptozocin results in increased expression of IRF2 mRNA]
CTD PMID:34212273 NCBI chr 8:47,192,751...47,300,493
Ensembl chr 8:47,192,767...47,300,493
JBrowse link
G Irs1 insulin receptor substrate 1 multiple interactions
decreases expression
decreases phosphorylation
EXP
ISO
[Dietary Fats co-treated with Streptozocin] results in decreased expression of IRS1 mRNA; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of IRS1 protein; [Streptozocin co-treated with Dietary Fats] affects the phosphorylation of IRS1 protein; [Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of IRS1 protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of IRS1 protein]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of IRS1 mRNA]; Metformin inhibits the reaction [Streptozocin results in decreased expression of IRS1 protein]; Metformin promotes the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of IRS1 protein]; perilla seed oil inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of IRS1 protein]; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] affects the phosphorylation of IRS1 protein]
[Dietary Fats co-treated with Streptozocin] results in decreased expression of IRS1 protein; [Streptozocin co-treated with Cadmium] results in decreased expression of IRS1 protein; asiatic acid inhibits the reaction [Streptozocin results in decreased expression of IRS1 protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of IRS1 protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased expression of IRS1 protein]; nerolidol inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of IRS1 protein]; Phosphocreatine inhibits the reaction [Streptozocin results in decreased phosphorylation of IRS1 protein]; Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of IRS1 mRNA]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of IRS1 mRNA]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of IRS1 protein]; Rivastigmine inhibits the reaction [Streptozocin results in decreased expression of IRS1 mRNA]; Wortmannin inhibits the reaction [Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of IRS1 mRNA]]
Streptozocin results in decreased expression of IRS1 mRNA; Streptozocin results in decreased expression of IRS1 protein
CTD PMID:23927877 PMID:24923654 PMID:26071184 PMID:26286522 PMID:26522834 More... NCBI chr 1:82,210,826...82,269,160
Ensembl chr 1:82,210,822...82,269,137
JBrowse link
G Irs2 insulin receptor substrate 2 multiple interactions
decreases expression
ISO
EXP
[Streptozocin co-treated with Cadmium] results in decreased expression of IRS2 protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of IRS2 protein; asiatic acid inhibits the reaction [Streptozocin results in decreased expression of IRS2 protein]; eupafolin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of IRS2 protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of IRS2 protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased expression of IRS2 protein]; myrtenal inhibits the reaction [Streptozocin results in decreased expression of IRS2 protein]; piperlongumine inhibits the reaction [Streptozocin results in decreased expression of IRS2 protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of IRS2 protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of IRS2 mRNA]
Streptozocin results in decreased expression of IRS2 mRNA; Streptozocin results in decreased expression of IRS2 protein
[Streptozocin co-treated with bisphenol A] results in decreased expression of IRS2 mRNA; [Streptozocin co-treated with octylphenol] results in decreased expression of IRS2 mRNA
CTD PMID:24923654 PMID:26071184 PMID:26286522 PMID:27417257 PMID:29935216 More... NCBI chr 8:11,034,681...11,058,929
Ensembl chr 8:11,034,681...11,058,458
JBrowse link
G Isyna1 myo-inositol 1-phosphate synthase A1 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of ISYNA1 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of ISYNA1 mRNA] CTD PMID:33484791 NCBI chr 8:71,047,131...71,049,940
Ensembl chr 8:71,047,023...71,049,940
JBrowse link
G Itga3 integrin alpha 3 multiple interactions
decreases expression
EXP
ISO
notoginsenoside R1 inhibits the reaction [Streptozocin results in decreased expression of ITGA3 mRNA]; notoginsenoside R1 inhibits the reaction [Streptozocin results in decreased expression of ITGA3 protein]
Streptozocin results in decreased expression of ITGA3 mRNA; Streptozocin results in decreased expression of ITGA3 protein
CTD PMID:25503068 NCBI chr11:94,935,301...94,967,637
Ensembl chr11:94,935,300...94,967,627
JBrowse link
G Itgal integrin alpha L multiple interactions
increases expression
ISO [resveratrol co-treated with Streptozocin] results in increased expression of ITGAL mRNA; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of ITGAL protein] CTD PMID:16129698 PMID:25905778 NCBI chr 7:126,895,404...126,934,309
Ensembl chr 7:126,895,432...126,934,310
JBrowse link
G Itgam integrin alpha M multiple interactions
increases expression
ISO Ibuprofen inhibits the reaction [Streptozocin results in increased expression of ITGAM mRNA]; Ibuprofen inhibits the reaction [Streptozocin results in increased expression of ITGAM protein]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of ITGAM protein]; Memantine inhibits the reaction [Streptozocin results in increased expression of ITGAM mRNA]; Memantine inhibits the reaction [Streptozocin results in increased expression of ITGAM protein]
Streptozocin results in increased expression of ITGAM mRNA; Streptozocin results in increased expression of ITGAM protein
CTD PMID:16129698 PMID:24333387 NCBI chr 7:127,661,812...127,717,663
Ensembl chr 7:127,661,812...127,717,663
JBrowse link
G Itgav integrin alpha V affects expression EXP Streptozocin affects the expression of ITGAV mRNA CTD PMID:26073000 NCBI chr 2:83,554,796...83,637,261
Ensembl chr 2:83,554,741...83,637,260
JBrowse link
G Itgb1 integrin beta 1 (fibronectin receptor beta) decreases expression
multiple interactions
ISO
EXP
Streptozocin results in decreased expression of ITGB1 mRNA; Streptozocin results in decreased expression of ITGB1 protein
notoginsenoside R1 inhibits the reaction [Streptozocin results in decreased expression of ITGB1 mRNA]; notoginsenoside R1 inhibits the reaction [Streptozocin results in decreased expression of ITGB1 protein]
CTD PMID:25503068 NCBI chr 8:129,412,135...129,460,060
Ensembl chr 8:129,412,135...129,459,681
JBrowse link
G Itgb2 integrin beta 2 multiple interactions
increases expression
ISO [resveratrol co-treated with Streptozocin] results in increased expression of ITGB2 mRNA; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of ITGB2 protein] CTD PMID:16129698 PMID:25905778 NCBI chr10:77,366,164...77,401,542
Ensembl chr10:77,366,086...77,401,542
JBrowse link
G Itpr3 inositol 1,4,5-triphosphate receptor 3 multiple interactions
increases expression
EXP [bisphenol A co-treated with Streptozocin] results in increased expression of ITPR3 mRNA; [octylphenol co-treated with Streptozocin] results in increased expression of ITPR3 mRNA
Streptozocin results in increased expression of ITPR3 mRNA
CTD PMID:29935216 NCBI chr17:27,275,976...27,341,197
Ensembl chr17:27,276,278...27,341,197
JBrowse link
G Jak2 Janus kinase 2 multiple interactions
increases expression
ISO 7-hydroxycoumarin inhibits the reaction [Streptozocin results in increased expression of JAK2 mRNA]; 7-hydroxycoumarin inhibits the reaction [Streptozocin results in increased expression of JAK2 protein]; [Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of JAK2 protein; dapagliflozin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of JAK2 protein]
Streptozocin results in increased expression of JAK2 mRNA; Streptozocin results in increased expression of JAK2 protein
CTD PMID:34391751 PMID:36650709 NCBI chr19:29,229,006...29,290,495
Ensembl chr19:29,229,228...29,290,480
JBrowse link
G Jun jun proto-oncogene multiple interactions
increases expression
ISO
EXP
resveratrol inhibits the reaction [Streptozocin results in increased expression of JUN protein]
formononetin inhibits the reaction [Streptozocin results in increased expression of JUN mRNA]; formononetin inhibits the reaction [Streptozocin results in increased expression of JUN protein]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of JUN mRNA]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Streptozocin promotes the reaction [JUN protein binds to MMP9 promoter]]; SIRT1 protein inhibits the reaction [Streptozocin promotes the reaction [JUN protein binds to PARP1 protein]]; Streptozocin promotes the reaction [JUN protein binds to MMP9 promoter]; Streptozocin promotes the reaction [JUN protein binds to PARP1 protein]
Streptozocin results in increased expression of JUN mRNA; Streptozocin results in increased expression of JUN protein
CTD PMID:26499206 PMID:28478229 PMID:30642005 PMID:35315182 NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459
JBrowse link
G Kcnab3 potassium voltage-gated channel, shaker-related subfamily, beta member 3 multiple interactions EXP [Dietary Fats co-treated with Streptozocin] results in increased expression of KCNAB3 mRNA; ginsenoside Rh4 affects the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of KCNAB3 mRNA] CTD PMID:33359794 NCBI chr11:69,217,084...69,223,867
Ensembl chr11:69,217,084...69,223,868
JBrowse link
G Kcnh1 potassium voltage-gated channel, subfamily H (eag-related), member 1 multiple interactions EXP [Dietary Fats co-treated with Streptozocin] results in increased expression of KCNH1 mRNA; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of KCNH1 mRNA] CTD PMID:33359794 NCBI chr 1:191,871,759...192,192,467
Ensembl chr 1:191,873,082...192,192,467
JBrowse link
G Kcnn2 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2 increases expression EXP Streptozocin results in increased expression of KCNN2 protein CTD PMID:30635400 NCBI chr18:45,401,754...45,818,954
Ensembl chr18:45,401,927...45,818,950
JBrowse link
G Kcnn4 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 increases expression
multiple interactions
ISO
EXP
Streptozocin increases expression of Kcnn4 mRNA and protein in thoracic aorta smooth muscle tissue
exendin-4 inhibits the reaction [Streptozocin increases expression of Kcnn4 mRNA and protein in thoracic aorta smooth muscle tissue]
streptozocin cotreated with high fat diet increases expression of Kcnn4 protein in aorta
RGD PMID:29167619 PMID:29167619 PMID:35149165 RGD:401784495, RGD:401784495, RGD:401784497 NCBI chr 7:24,069,750...24,084,635
Ensembl chr 7:24,069,688...24,086,115
JBrowse link
G Kcnt1 potassium channel, subfamily T, member 1 multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of KCNT1 mRNA CTD PMID:33484791 NCBI chr 2:25,753,807...25,808,285
Ensembl chr 2:25,753,746...25,808,285
JBrowse link
G Kdr kinase insert domain protein receptor multiple interactions
increases expression
ISO
EXP
Simvastatin inhibits the reaction [Streptozocin results in increased expression of KDR mRNA]; Simvastatin inhibits the reaction [Streptozocin results in increased phosphorylation of and results in increased expression of KDR protein]; Streptozocin results in increased phosphorylation of and results in increased expression of KDR protein
Streptozocin results in increased expression of KDR mRNA; Streptozocin results in increased expression of KDR protein
[Dietary Fats co-treated with Streptozocin] results in increased expression of KDR protein; Rosuvastatin Calcium inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of KDR protein]; sarpogrelate inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of KDR protein]
CTD PMID:15643138 PMID:20821229 PMID:27097221 NCBI chr 5:76,093,487...76,139,880
Ensembl chr 5:76,093,487...76,139,118
JBrowse link
G Keap1 kelch-like ECH-associated protein 1 multiple interactions
decreases expression
increases expression
ISO
EXP
[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of KEAP1 mRNA; [Streptozocin co-treated with Niacinamide] results in increased expression of KEAP1 mRNA; [Streptozocin co-treated with Niacinamide] results in increased expression of KEAP1 protein; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of KEAP1 mRNA]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of KEAP1 mRNA]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of KEAP1 protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of KEAP1 mRNA]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of KEAP1 protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of KEAP1 mRNA]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of KEAP1 mRNA]; isoquercitrin inhibits the reaction [Streptozocin results in decreased expression of KEAP1 mRNA]; Metformin inhibits the reaction [Streptozocin results in increased expression of KEAP1 mRNA]; Metformin inhibits the reaction [Streptozocin results in increased expression of KEAP1 protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of KEAP1 mRNA]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of KEAP1 protein]; rhapontin inhibits the reaction [Streptozocin results in increased expression of KEAP1 mRNA]; rhapontin inhibits the reaction [Streptozocin results in increased expression of KEAP1 protein]
Streptozocin results in increased expression of KEAP1 mRNA; Streptozocin results in increased expression of KEAP1 protein
2,5-dihydroxybenzoic acid promotes the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of KEAP1 mRNA]; [Streptozocin co-treated with Dietary Fats] results in increased expression of KEAP1 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of KEAP1 protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of KEAP1 mRNA; Acrylamide inhibits the reaction [Streptozocin results in increased expression of KEAP1 mRNA]; Metformin promotes the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of KEAP1 mRNA]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of KEAP1 mRNA]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of KEAP1 protein]
CTD PMID:21439372 PMID:30817903 PMID:32662907 PMID:33639173 PMID:34610774 More... NCBI chr 9:21,141,026...21,150,628
Ensembl chr 9:21,141,026...21,150,657
JBrowse link
G Kel Kell blood group multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of KEL mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of KEL mRNA] CTD PMID:33484791 NCBI chr 6:41,663,263...41,681,268
Ensembl chr 6:41,663,264...41,681,273
JBrowse link
G Kl klotho decreases expression
multiple interactions
ISO Streptozocin results in decreased expression of KL
rosiglitazone inhibits the reaction [Streptozocin results in decreased expression of KL]
CTD PMID:24136780 NCBI chr 5:150,876,072...150,917,282
Ensembl chr 5:150,876,072...150,917,282
JBrowse link
G Klf15 Kruppel-like transcription factor 15 multiple interactions EXP [Dietary Fats co-treated with Streptozocin] promotes the reaction [KLF15 gene mutant form results in increased expression of CCN2 protein]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of KLF15 protein; CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of KLF15 protein]; KLF15 gene mutant form inhibits the reaction [CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CCN2 protein]]; KLF15 gene mutant form inhibits the reaction [CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FN1 protein]]; KLF15 gene mutant form inhibits the reaction [CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein]]; KLF15 gene mutant form promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CCN2 protein]; KLF15 gene mutant form promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FN1 protein]; KLF15 gene mutant form promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein]; KLF15 gene mutant form results in increased susceptibility to [Dietary Fats co-treated with Streptozocin] CTD PMID:34310909 NCBI chr 6:90,437,785...90,468,785
Ensembl chr 6:90,439,558...90,452,220
JBrowse link
G Klf4 Kruppel-like transcription factor 4 (gut) multiple interactions ISO [Resveratrol co-treated with Streptozocin] results in increased expression of KLF4 mRNA; [Streptozocin co-treated with Niacinamide] promotes the reaction [Dronabinol results in increased expression of KLF4 mRNA] CTD PMID:25905778 PMID:31081965 NCBI chr 4:55,527,137...55,536,984
Ensembl chr 4:55,527,143...55,532,466
JBrowse link
G Klk1 kallikrein 1 multiple interactions
increases expression
ISO
EXP
KLK1 protein inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of ITGAL protein]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of ITGAM protein]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of ITGB2 protein]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of TNF protein]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of VCAM1 protein]
Streptozocin results in increased expression of KLK1 mRNA
CTD PMID:16129698 PMID:19516248 NCBI chr 7:43,874,784...43,879,046
Ensembl chr 7:43,874,784...43,879,042
JBrowse link
G Klk1b4 kallikrein 1-related pepidase b4 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of KLK1B4 mRNA CTD PMID:29127188 NCBI chr 7:43,856,857...43,861,178
Ensembl chr 7:43,856,859...43,861,178
JBrowse link
G Kng1 kininogen 1 multiple interactions
increases response to substance
ISO Streptozocin promotes the reaction [KNG1 protein modified form results in increased secretion of Dinoprostone]; Streptozocin promotes the reaction [KNG1 protein modified form results in increased secretion of TAC1 protein modified form]
Streptozocin results in increased susceptibility to KNG1 protein modified form
CTD PMID:20832942 NCBI chr16:22,876,970...22,900,828
Ensembl chr16:22,876,615...22,900,828
JBrowse link
G Krt19 keratin 19 multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of KRT19 mRNA CTD PMID:25905778 NCBI chr11:100,031,636...100,036,752
Ensembl chr11:100,031,636...100,039,491
JBrowse link
G Kynu kynureninase multiple interactions ISO [resveratrol co-treated with Streptozocin] results in decreased expression of KYNU mRNA CTD PMID:25905778 NCBI chr 2:43,445,270...43,572,734
Ensembl chr 2:43,445,341...43,572,734
JBrowse link
G Lama1 laminin, alpha 1 multiple interactions EXP [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of LAMA1 protein]; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of LAMA1 protein CTD PMID:38282657 NCBI chr17:68,004,129...68,129,640
Ensembl chr17:68,004,254...68,129,642
JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 multiple interactions ISO [[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in decreased expression of LAMP1 mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of LAMP1 mRNA; [Carbamazepine affects the susceptibility to [Dietary Fats co-treated with Streptozocin]] which results in decreased expression of LAMP1 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of LAMP1 mRNA CTD PMID:35786680 NCBI chr 8:13,209,161...13,225,338
Ensembl chr 8:13,209,161...13,225,338
JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 multiple interactions ISO [[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in decreased expression of LAMP2 mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of LAMP2 mRNA; [Carbamazepine affects the susceptibility to [Dietary Fats co-treated with Streptozocin]] which results in decreased expression of LAMP2 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of LAMP2 mRNA CTD PMID:35786680 NCBI chr  X:37,488,524...37,545,337
Ensembl chr  X:37,490,234...37,545,331
JBrowse link
G Lap3 leucine aminopeptidase 3 affects expression EXP Streptozocin affects the expression of LAP3 mRNA CTD PMID:18583417 NCBI chr 5:45,650,716...45,670,033
Ensembl chr 5:45,650,716...45,670,033
JBrowse link
G Laptm5 lysosomal-associated protein transmembrane 5 multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of LAPTM5 mRNA CTD PMID:25905778 NCBI chr 4:130,640,627...130,663,459
Ensembl chr 4:130,640,436...130,663,452
JBrowse link
G Lcat lecithin cholesterol acyltransferase multiple interactions ISO
EXP
[Streptozocin co-treated with Cadmium] results in decreased activity of LCAT protein; [Streptozocin co-treated with Niacinamide] results in decreased activity of LCAT protein; [tetrahydrocurcumin co-treated with Chlorogenic Acid] results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in decreased activity of LCAT protein]; Chlorogenic Acid results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in decreased activity of LCAT protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased activity of LCAT protein]; tetrahydrocurcumin results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in decreased activity of LCAT protein]
[Streptozocin co-treated with Dietary Fats] results in decreased expression of LCAT protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of LCAT protein]
CTD PMID:20696151 PMID:25240712 PMID:33484791 NCBI chr 8:106,666,183...106,670,034
Ensembl chr 8:106,666,183...106,670,014
JBrowse link
G Lcn2 lipocalin 2 multiple interactions ISO
EXP
[Resveratrol co-treated with Streptozocin] results in increased expression of LCN2 mRNA; [Streptozocin co-treated with Fructose] results in increased expression of LCN2 protein; [Streptozocin co-treated with iomeprol] results in increased expression of LCN2 protein; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of LCN2 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of LCN2 protein]; palmidrol analog inhibits the reaction [[Streptozocin co-treated with iomeprol] results in increased expression of LCN2 protein]
[Streptozocin co-treated with Dietary Fats] results in increased expression of LCN2 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of LCN2 mRNA]
CTD PMID:25905778 PMID:26474837 PMID:30551545 PMID:33484791 NCBI chr 2:32,274,649...32,277,751
Ensembl chr 2:32,274,645...32,278,264
JBrowse link
G Ldhb lactate dehydrogenase B increases expression
multiple interactions
ISO Streptozocin results in increased expression of LDHB protein
Trientine inhibits the reaction [Streptozocin results in increased expression of LDHB protein]
CTD PMID:19634143 PMID:21136691 NCBI chr 6:142,435,975...142,453,683
Ensembl chr 6:142,435,975...142,453,683
JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions
decreases expression
EXP [Dietary Fats co-treated with Streptozocin] results in decreased expression of LDLR mRNA; Acrylamide inhibits the reaction [Streptozocin results in decreased expression of LDLR mRNA]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of LDLR mRNA] CTD PMID:33359794 PMID:34896238 NCBI chr 9:21,634,872...21,661,215
Ensembl chr 9:21,634,779...21,661,215
JBrowse link
G Lep leptin multiple interactions ISO
EXP
[Streptozocin co-treated with Dietary Fats] results in increased expression of LEP protein; morin analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of LEP protein]; Zinc Compounds inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of LEP protein]
[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of LEP protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of LEP protein; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of LEP protein]; Omaveloxolone analog promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of LEP protein]
CTD PMID:24854284 PMID:29988851 PMID:32410268 NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876
JBrowse link
G Lepr leptin receptor multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of LEPR mRNA CTD PMID:29127188 NCBI chr 4:101,574,393...101,676,375
Ensembl chr 4:101,574,601...101,672,549
JBrowse link
G Lgals3 lectin, galactose binding, soluble 3 multiple interactions
increases expression
ISO [resveratrol co-treated with Streptozocin] results in increased expression of LGALS3 mRNA; vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of LGALS3 mRNA] CTD PMID:16684804 PMID:25905778 NCBI chr14:47,611,317...47,623,624
Ensembl chr14:47,605,208...47,623,617
JBrowse link
G Lhb luteinizing hormone beta decreases expression
multiple interactions
ISO
EXP
Streptozocin results in decreased expression of LHB protein
Sildenafil Citrate inhibits the reaction [Streptozocin results in decreased expression of LHB protein]; vitexin inhibits the reaction [Streptozocin results in decreased expression of LHB protein]
[Streptozocin co-treated with Fructose] results in decreased expression of LHB protein; Acetates inhibits the reaction [[Streptozocin co-treated with Fructose] results in decreased expression of LHB protein]; carvacrol affects the reaction [Streptozocin results in decreased expression of LHB protein]
CTD PMID:19931367 PMID:30365938 PMID:32153207 PMID:34656705 NCBI chr 7:45,070,370...45,071,278
Ensembl chr 7:45,070,244...45,071,321
JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor multiple interactions
decreases expression
ISO carvacrol affects the reaction [Streptozocin results in decreased expression of LHCGR mRNA]; carvacrol affects the reaction [Streptozocin results in decreased expression of LHCGR protein]
Streptozocin results in decreased expression of LHCGR mRNA; Streptozocin results in decreased expression of LHCGR protein
CTD PMID:32153207 NCBI chr17:89,023,812...89,099,487
Ensembl chr17:89,023,909...89,099,418
JBrowse link
G Limk2 LIM domain kinase 2 multiple interactions
increases phosphorylation
ISO fasudil inhibits the reaction [Streptozocin results in increased phosphorylation of LIMK2 protein] CTD PMID:22062134 NCBI chr11:3,293,297...3,359,238
Ensembl chr11:3,294,256...3,359,189
JBrowse link
G Lipc lipase, hepatic multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of LIPC protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of LIPC protein] CTD PMID:33484791 NCBI chr 9:70,705,410...70,859,503
Ensembl chr 9:70,705,410...70,859,508
JBrowse link
G Lipe lipase, hormone sensitive multiple interactions
increases expression
ISO
EXP
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of LIPE mRNA]
[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of HSL mRNA
CTD PMID:16684804 PMID:39047806 NCBI chr 7:25,078,952...25,097,911
Ensembl chr 7:25,078,952...25,098,135
JBrowse link
G Litaf LPS-induced TN factor decreases expression ISO Streptozocin results in decreased expression of LITAF mRNA CTD PMID:25905778 NCBI chr16:10,777,137...10,810,985
Ensembl chr16:10,777,139...10,884,021
JBrowse link
G Lncpint long non-protein coding RNA, Trp53 induced transcript multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of LNCPINT mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of LNCPINT mRNA] CTD PMID:33484791 NCBI chr 6:31,070,498...31,195,409
Ensembl chr 6:31,059,500...31,197,607
JBrowse link
G Lpin2 lipin 2 increases expression ISO Streptozocin results in increased expression of LPIN2 mRNA CTD PMID:25905778 NCBI chr17:71,490,527...71,556,813
Ensembl chr17:71,489,555...71,556,812
JBrowse link
G Lpl lipoprotein lipase multiple interactions ISO
EXP
[Streptozocin co-treated with Cadmium] results in decreased activity of LPL protein; [Streptozocin co-treated with Niacinamide] results in decreased activity of LPL protein; [tetrahydrocurcumin co-treated with Chlorogenic Acid] results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in decreased activity of LPL protein]; Chlorogenic Acid results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in decreased activity of LPL protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased activity of LPL protein]; tetrahydrocurcumin results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in decreased activity of LPL protein]
[1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of LPL mRNA]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of LPL mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of LPL mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of LPL mRNA; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of LPL mRNA]
CTD PMID:20696151 PMID:25240712 PMID:25446853 PMID:29127188 PMID:39047806 NCBI chr 8:69,333,207...69,359,584
Ensembl chr 8:69,333,143...69,360,100
JBrowse link
G Lrp5 low density lipoprotein receptor-related protein 5 affects expression EXP Streptozocin affects the expression of LRP5 mRNA CTD PMID:18583417 NCBI chr19:3,634,825...3,736,574
Ensembl chr19:3,634,828...3,736,564
JBrowse link
G Lst1 leukocyte specific transcript 1 multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of LST1 mRNA CTD PMID:25905778 NCBI chr17:35,404,071...35,407,416
Ensembl chr17:35,404,071...35,407,415
JBrowse link
G Ly6c1 lymphocyte antigen 6 family member C1 multiple interactions EXP [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of LY6C1 mRNA; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of LY6C1 mRNA] CTD PMID:39047806 NCBI chr15:74,915,867...74,920,690
Ensembl chr15:74,915,867...74,920,679
JBrowse link
G Ly6g lymphocyte antigen 6 family member G multiple interactions EXP [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of LY6G mRNA; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of LY6G mRNA] CTD PMID:39047806 NCBI chr15:75,027,110...75,030,977
Ensembl chr15:75,027,089...75,030,975
JBrowse link
G Lyz2 lysozyme 2 increases expression
multiple interactions
ISO Streptozocin results in increased expression of LYZ mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of LYZ mRNA]
CTD PMID:16684804 NCBI chr10:117,113,446...117,118,177
Ensembl chr10:117,113,236...117,118,226
JBrowse link
G Mafa MAF bZIP transcription factor A multiple interactions
decreases expression
EXP [Dietary Fats co-treated with Streptozocin] results in decreased expression of MAFA mRNA; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of MAFA mRNA]; octylphenol inhibits the reaction [Streptozocin results in decreased expression of MAFA mRNA] CTD PMID:24781736 PMID:29935216 PMID:33359794 NCBI chr15:75,617,350...75,620,170
Ensembl chr15:75,617,339...75,620,077
JBrowse link
G Mak male germ cell-associated kinase multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of MAK mRNA CTD PMID:33484791 NCBI chr13:41,178,483...41,233,182
Ensembl chr13:41,178,484...41,233,182
JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha multiple interactions ISO [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in increased expression of MAP1LC3A protein CTD PMID:35786680 NCBI chr 2:155,118,284...155,119,993
Ensembl chr 2:155,118,217...155,119,993
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions
increases lipidation
decreases expression
increases expression
ISO [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of MAP1LC3B mRNA; [Zinc co-treated with Selenium] inhibits the reaction [Streptozocin results in increased expression of MAP1LC3B protein]; dapagliflozin inhibits the reaction [Streptozocin results in decreased expression of MAP1LC3B mRNA]
Streptozocin results in increased lipidation of MAP1LC3B protein
CTD PMID:32233808 PMID:35786680 PMID:37352119 PMID:38706688 NCBI chr 8:122,317,177...122,325,499
Ensembl chr 8:122,317,100...122,325,499
JBrowse link
G Map2 microtubule-associated protein 2 multiple interactions
decreases expression
EXP
ISO
Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of MAP2 protein]; Physostigmine inhibits the reaction [Streptozocin results in decreased expression of MAP2 protein]
Vitamin B 12 inhibits the reaction [Streptozocin results in decreased expression of MAP2 protein]
CTD PMID:28499986 PMID:38049026 NCBI chr 1:66,214,337...66,481,742
Ensembl chr 1:66,214,432...66,481,742
JBrowse link
G Map2k4 mitogen-activated protein kinase kinase 4 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAP2K4 protein; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAP2K4 protein] CTD PMID:26522834 NCBI chr11:65,579,070...65,679,185
Ensembl chr11:65,579,069...65,679,123
JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 increases expression ISO Streptozocin results in increased expression of MAP2K6 mRNA CTD PMID:25905778 NCBI chr11:110,289,928...110,416,348
Ensembl chr11:110,289,948...110,416,348
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 multiple interactions
increases expression
EXP
ISO
[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAP3K5 protein; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAP3K5 protein]; Streptozocin promotes the reaction [MAP3K5 protein results in increased expression of SERPINE1 protein]
resveratrol inhibits the reaction [Streptozocin results in increased expression of MAP3K5 protein]
CTD PMID:16731828 PMID:26499206 PMID:26522834 NCBI chr10:19,809,847...20,018,496
Ensembl chr10:19,810,218...20,018,499
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions
increases activity
increases expression
increases phosphorylation
decreases phosphorylation
ISO
EXP
1,3-dimethoxy-5-methyl-2-(3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl)benzene inhibits the reaction [4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in decreased phosphorylation of MAPK1 protein]]; 4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in decreased phosphorylation of MAPK1 protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein]; baicalin inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein]; Botulinum Toxins, Type A inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein]; capsazepine inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein]; Donepezil inhibits the reaction [Streptozocin results in decreased phosphorylation of MAPK1 protein]; Memantine inhibits the reaction [Streptozocin results in decreased phosphorylation of MAPK1 protein]; Metformin inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of MAPK1 mRNA]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of MAPK1 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein]; RN 1734 inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein]; Streptozocin results in increased phosphorylation of and results in increased activity of MAPK1 protein; U 0126 inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein]; xanthoceraside inhibits the reaction [Streptozocin results in decreased phosphorylation of MAPK1 protein]
Streptozocin results in increased activity of MAPK1 protein
Streptozocin results in increased expression of MAPK1 mRNA; Streptozocin results in increased expression of MAPK1 protein
Streptozocin inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK1 protein]
3-((6-(2-methoxyphenyl)pyrimidin-4-yl)amino)phenyl)methane sulfonamide inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein]; [Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of and results in decreased phosphorylation of MAPK1 protein; [Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased phosphorylation of MAPK1 protein; [Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAPK1 protein; arachidonyl-2-chloroethylamide promotes the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein]; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAPK1 protein]; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of and results in decreased phosphorylation of MAPK1 protein]; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased phosphorylation of MAPK1 protein]; Streptozocin promotes the reaction [NTN1 protein results in increased phosphorylation of MAPK1 protein]
CTD PMID:12642375 PMID:17063547 PMID:19002579 PMID:19133311 PMID:19682444 More... NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk10 mitogen-activated protein kinase 10 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of MAPK10 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of MAPK10 mRNA] CTD PMID:33484791 NCBI chr 5:103,056,413...103,359,200
Ensembl chr 5:103,055,814...103,359,200
JBrowse link
G Mapk11 mitogen-activated protein kinase 11 multiple interactions EXP [Dietary Fats co-treated with Streptozocin] results in increased expression of MAPK11 protein CTD PMID:34310909 NCBI chr15:89,026,685...89,033,809
Ensembl chr15:89,026,689...89,033,831
JBrowse link
G Mapk14 mitogen-activated protein kinase 14 increases phosphorylation
multiple interactions
EXP
ISO
Streptozocin results in increased phosphorylation of MAPK14 protein
Atorvastatin inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK14 protein]
CTD PMID:15232685 PMID:17589825 NCBI chr17:28,910,316...28,967,379
Ensembl chr17:28,910,303...28,967,380
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 increases activity
increases expression
multiple interactions
increases phosphorylation
decreases phosphorylation
ISO
EXP
Streptozocin results in increased activity of MAPK3 protein
Streptozocin results in increased expression of MAPK3 mRNA
1,3-dimethoxy-5-methyl-2-(3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl)benzene inhibits the reaction [4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in decreased phosphorylation of MAPK3 protein]]; 4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in decreased phosphorylation of MAPK3 protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased phosphorylation of and results in increased activity of MAPK3 protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein]; baicalin inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein]; Botulinum Toxins, Type A inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein]; capsazepine inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein]; Donepezil inhibits the reaction [Streptozocin results in decreased phosphorylation of MAPK3 protein]; Memantine inhibits the reaction [Streptozocin results in decreased phosphorylation of MAPK3 protein]; Metformin inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein]; RN 1734 inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein]; Streptozocin results in increased phosphorylation of and results in increased activity of MAPK3 protein; U 0126 inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein]; xanthoceraside inhibits the reaction [Streptozocin results in decreased phosphorylation of MAPK3 protein]
Streptozocin inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK3 protein]
3-((6-(2-methoxyphenyl)pyrimidin-4-yl)amino)phenyl)methane sulfonamide inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein]; [Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased phosphorylation of MAPK3 protein; [Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAPK3 protein; arachidonyl-2-chloroethylamide promotes the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein]; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAPK3 protein]; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased phosphorylation of MAPK3 protein]; Streptozocin promotes the reaction [NTN1 protein results in increased phosphorylation of MAPK3 protein]
CTD PMID:12642375 PMID:19002579 PMID:19133311 PMID:19682444 PMID:20053369 More... NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions
increases phosphorylation
ISO
EXP
Streptozocin inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK8 protein]
[Carnosine co-treated with asiatic acid] inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein]; [Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAPK8 protein; asiatic acid inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein]; Carnosine inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein]; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAPK8 protein]; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAPK8 protein]
[Resveratrol co-treated with Ramipril] inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein]; Ramipril inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein]
CTD PMID:25541468 PMID:26522834 PMID:30802477 PMID:31062909 PMID:33484791 NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions
increases expression
ISO
EXP
chromium mesoporphyrin inhibits the reaction [Hemin inhibits the reaction [Streptozocin results in increased expression of MAPK9 mRNA]]; Hemin inhibits the reaction [Streptozocin results in increased expression of MAPK9 mRNA]
Streptozocin inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK9 protein]
[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAPK9 protein; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAPK9 protein]
CTD PMID:19190261 PMID:25541468 PMID:26522834 NCBI chr11:49,737,558...49,777,248
Ensembl chr11:49,737,578...49,777,248
JBrowse link
G Mapkapk2 MAP kinase-activated protein kinase 2 multiple interactions
increases expression
EXP telmisartan inhibits the reaction [Streptozocin results in increased expression of MAPKAPK2 protein modified form] CTD PMID:21381899 NCBI chr 1:130,981,437...131,025,580
Ensembl chr 1:130,981,437...131,025,563
JBrowse link
G Mapt microtubule-associated protein tau increases phosphorylation
multiple interactions
increases expression
EXP
ISO
Streptozocin results in increased phosphorylation of MAPT protein
5-Methoxypsoralen inhibits the reaction [Streptozocin results in increased expression of MAPT protein modified form]; Folic Acid inhibits the reaction [Streptozocin results in increased phosphorylation of MAPT protein]; SOD2 protein inhibits the reaction [Streptozocin results in increased phosphorylation of MAPT protein]; Tadalafil inhibits the reaction [Streptozocin results in increased expression of MAPT protein modified form]
Melatonin inhibits the reaction [Streptozocin results in increased phosphorylation of MAPT protein]; Melatonin metabolite inhibits the reaction [Streptozocin results in increased phosphorylation of MAPT protein]; N-acetyl-N-formyl-5-methoxykynurenamine inhibits the reaction [Streptozocin results in increased phosphorylation of MAPT protein]
CTD PMID:20976160 PMID:28422052 PMID:31833155 PMID:34428446 NCBI chr11:104,120,235...104,222,916
Ensembl chr11:104,122,216...104,222,916
JBrowse link
G Mas1 MAS1 oncogene decreases expression
multiple interactions
EXP Streptozocin results in decreased expression of MAS1 protein
CEBPB protein inhibits the reaction [Streptozocin results in decreased expression of MAS1 protein]; Telmisartan inhibits the reaction [Streptozocin results in decreased expression of MAS1 protein]
CTD PMID:21381899 PMID:29266779 NCBI chr17:13,056,981...13,087,037
Ensembl chr17:13,059,966...13,087,030
JBrowse link
G Mat1a methionine adenosyltransferase 1A multiple interactions EXP [Streptozocin co-treated with Dietary Fats] affects the expression of MAT1A mRNA CTD PMID:29127188 NCBI chr14:40,826,969...40,846,385
Ensembl chr14:40,826,992...40,846,369
JBrowse link
G Mat2a methionine adenosyltransferase 2A multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of MAT2A mRNA CTD PMID:29127188 NCBI chr 6:72,409,779...72,416,539
Ensembl chr 6:72,409,782...72,416,541
JBrowse link
G Mbp myelin basic protein multiple interactions
decreases expression
ISO 20-alpha-Dihydroprogesterone inhibits the reaction [Streptozocin results in decreased expression of MBP mRNA]; Progesterone inhibits the reaction [Streptozocin results in decreased expression of MBP mRNA]; Vitamin B 12 inhibits the reaction [Streptozocin results in decreased expression of MBP protein]
Streptozocin results in decreased expression of MBP mRNA; Streptozocin results in decreased expression of MBP protein
CTD PMID:20349157 PMID:38049026 NCBI chr18:82,492,883...82,603,762
Ensembl chr18:82,493,271...82,603,762
JBrowse link
G Mcemp1 mast cell expressed membrane protein 1 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of MCEMP1 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of MCEMP1 mRNA] CTD PMID:33484791 NCBI chr 8:3,715,754...3,718,916
Ensembl chr 8:3,715,754...3,719,259
JBrowse link
G Mdh1 malate dehydrogenase 1, NAD (soluble) multiple interactions
increases expression
ISO Trientine inhibits the reaction [Streptozocin results in increased expression of MDH1 protein] CTD PMID:21136691 NCBI chr11:21,506,692...21,521,934
Ensembl chr11:21,506,692...21,522,367
JBrowse link
G Mdh2 malate dehydrogenase 2, NAD (mitochondrial) decreases expression
multiple interactions
ISO Streptozocin results in decreased expression of MDH2 protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of MDH2 protein]
CTD PMID:19634143 NCBI chr 5:135,807,503...135,819,240
Ensembl chr 5:135,807,334...135,819,252
JBrowse link
G Mecr mitochondrial trans-2-enoyl-CoA reductase increases expression ISO Streptozocin results in increased expression of MECR mRNA CTD PMID:25905778 NCBI chr 4:131,570,755...131,595,097
Ensembl chr 4:131,570,781...131,595,097
JBrowse link
G Mef2c myocyte enhancer factor 2C decreases expression
multiple interactions
EXP
ISO
Streptozocin results in decreased expression of MEF2C mRNA
SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of MEF2C mRNA]
CTD PMID:27629361 NCBI chr13:83,652,136...83,815,197
Ensembl chr13:83,652,153...83,815,199
JBrowse link
G Mefv Mediterranean fever multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of MEFV mRNA CTD PMID:33484791 NCBI chr16:3,524,838...3,536,073
Ensembl chr16:3,525,082...3,535,961
JBrowse link
G Mep1a meprin 1 alpha multiple interactions ISO Streptozocin results in decreased activity of and results in decreased expression of MEP1A protein CTD PMID:15942051 NCBI chr17:43,785,215...43,815,034
Ensembl chr17:43,785,215...43,813,703
JBrowse link
G Mff mitochondrial fission factor multiple interactions EXP [Dietary Fats co-treated with Streptozocin] results in increased expression of MFF mRNA CTD PMID:33812996 NCBI chr 1:82,702,599...82,730,111
Ensembl chr 1:82,702,611...82,730,115
JBrowse link
G Mfn2 mitofusin 2 multiple interactions
decreases expression
ISO
EXP
ferulic acid inhibits the reaction [Streptozocin results in decreased expression of MFN2 protein]; MFN2 protein mutant form inhibits the reaction [Streptozocin promotes the reaction [TFAP2A protein binds to COL4A1 promoter]]; MFN2 protein mutant form inhibits the reaction [Streptozocin results in increased expression of COL4A1 mRNA]
[Dietary Fats co-treated with Streptozocin] results in decreased expression of MFN2 mRNA; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of MFN2 mRNA]
CTD PMID:27997345 PMID:31029786 PMID:33812996 NCBI chr 4:147,958,043...147,989,527
Ensembl chr 4:147,958,056...147,989,161
JBrowse link
G Mgll monoglyceride lipase multiple interactions ISO [resveratrol co-treated with Streptozocin] results in decreased expression of MGLL mRNA CTD PMID:25905778 NCBI chr 6:88,701,397...88,805,342
Ensembl chr 6:88,701,394...88,805,342
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase decreases response to substance ISO MGMT protein results in decreased susceptibility to Streptozocin CTD PMID:16039682 NCBI chr 7:136,496,315...136,732,001
Ensembl chr 7:136,496,343...136,731,995
JBrowse link
G Mgst2 microsomal glutathione S-transferase 2 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of MGST2 mRNA CTD PMID:29127188 NCBI chr 3:51,544,179...51,590,096
Ensembl chr 3:51,567,781...51,590,098
JBrowse link
G Micu1 mitochondrial calcium uptake 1 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of MICU1 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of MICU1 protein; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of MICU1 mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of MICU1 protein]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of MICU1 mRNA]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of MICU1 protein] CTD PMID:37337224 NCBI chr10:59,538,385...59,699,956
Ensembl chr10:59,538,299...59,699,954
JBrowse link
G Mir100 microRNA 100 decreases expression EXP Streptozocin results in decreased expression of MIR100 mRNA CTD PMID:27629361 NCBI chr 9:41,442,721...41,442,800
Ensembl chr 9:41,442,721...41,442,800
JBrowse link
G Mir101b microRNA 101b increases expression EXP Streptozocin results in increased expression of MIR101B mRNA CTD PMID:27629361 NCBI chr19:29,112,679...29,112,775
Ensembl chr19:29,112,679...29,112,775
JBrowse link
G Mir106a microRNA 106a increases expression EXP Streptozocin results in increased expression of MIR106A mRNA CTD PMID:27629361 NCBI chr  X:51,831,380...51,831,444
Ensembl chr  X:51,831,380...51,831,444
JBrowse link
G Mir10a microRNA 10a multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of MIR10A mRNA; HDAC3 protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of MIR10A mRNA]; MIR10A mRNA affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CREB1 protein] CTD PMID:27292126 NCBI chr11:96,207,991...96,208,100
Ensembl chr11:96,207,991...96,208,100
JBrowse link
G Mir1188 microRNA 1188 increases expression EXP Streptozocin results in increased expression of MIR1188 mRNA CTD PMID:27629361 NCBI chr12:109,578,256...109,578,375
Ensembl chr12:109,578,256...109,578,375
JBrowse link
G Mir1190 microRNA 1190 increases expression EXP Streptozocin results in increased expression of MIR1190 mRNA CTD PMID:27629361 NCBI chr12:100,987,932...100,988,027
Ensembl chr12:100,987,932...100,988,027
JBrowse link
G Mir1251 microRNA 1251 increases expression EXP Streptozocin results in increased expression of MIR1251 mRNA CTD PMID:27629361 NCBI chr10:91,973,002...91,973,085
Ensembl chr10:91,973,002...91,973,085
JBrowse link
G Mir125b-1 microRNA 125b-1 increases expression EXP Streptozocin results in increased expression of MIR125B-1 mRNA CTD PMID:27629361 NCBI chr 9:41,493,222...41,493,298
Ensembl chr 9:41,493,222...41,493,298
JBrowse link
G Mir128-1 microRNA 128-1 increases expression EXP Streptozocin results in increased expression of MIR128-1 mRNA CTD PMID:27629361 NCBI chr 1:128,130,098...128,130,167
Ensembl chr 1:128,130,098...128,130,167
JBrowse link
G Mir1298 microRNA 1298 increases expression EXP Streptozocin results in increased expression of MIR1298 mRNA CTD PMID:27629361 NCBI chr  X:145,847,901...145,847,998
Ensembl chr  X:145,847,901...145,847,998
JBrowse link
G Mir1306 microRNA 1306 increases expression EXP Streptozocin results in increased expression of MIR1306 mRNA CTD PMID:27629361 NCBI chr16:18,102,103...18,102,181
Ensembl chr16:18,102,103...18,102,181
JBrowse link
G Mir132 microRNA 132 increases expression EXP Streptozocin results in increased expression of MIR132 mRNA CTD PMID:27629361 NCBI chr11:75,064,508...75,064,573
Ensembl chr11:75,064,508...75,064,573
JBrowse link
G Mir135a-2 microRNA 135a-2 increases expression EXP Streptozocin results in increased expression of MIR135A-2 mRNA CTD PMID:27629361 NCBI chr10:91,907,948...91,908,047
Ensembl chr10:91,907,948...91,908,047
JBrowse link
G Mir135b microRNA 135b increases expression EXP Streptozocin results in increased expression of MIR135B mRNA CTD PMID:27629361 NCBI chr 1:132,125,826...132,125,922
Ensembl chr 1:132,125,826...132,125,922
JBrowse link
G Mir140 microRNA 140 multiple interactions
increases expression
ISO
EXP
[Antagomirs results in decreased expression of MIR140 mRNA] inhibits the reaction [Streptozocin results in decreased expression of SNX12 protein]
streptozocin increases expression of Mir140 RNA in heart
CTD
RGD
PMID:32062618 PMID:36044268 RGD:156430337 NCBI chr 8:108,277,876...108,277,945
Ensembl chr 8:108,277,876...108,277,945
JBrowse link
G Mir142 microRNA 142 increases expression
multiple interactions
EXP
ISO
Streptozocin results in increased expression of MIR142 mRNA
SOD1 protein inhibits the reaction [Streptozocin results in increased expression of MIR142 mRNA]
CTD PMID:27629361 NCBI chr11:87,647,690...87,647,753
Ensembl chr11:87,647,690...87,647,753
JBrowse link
G Mir144 microRNA 144 increases expression
multiple interactions
EXP
ISO
Streptozocin results in increased expression of MIR144 mRNA
SOD1 protein inhibits the reaction [Streptozocin results in increased expression of MIR144 mRNA]
CTD PMID:27629361 NCBI chr11:77,963,831...77,963,896
Ensembl chr11:77,963,831...77,963,896
JBrowse link
G Mir146 microRNA 146 multiple interactions
increases expression
ISO Glyburide inhibits the reaction [Streptozocin results in increased expression of MIR146A mRNA]; Tropisetron inhibits the reaction [Streptozocin results in increased expression of MIR146A mRNA] CTD PMID:36504472 NCBI chr11:43,265,224...43,265,288
Ensembl chr11:43,265,224...43,265,288
JBrowse link
G Mir146b microRNA 146b increases expression EXP Streptozocin results in increased expression of MIR146B mRNA CTD PMID:27629361 NCBI chr19:46,331,201...46,331,309
Ensembl chr19:46,331,201...46,331,309
JBrowse link
G Mir152 microRNA 152 multiple interactions ISO [Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in increased expression of MIR152 mRNA]; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in increased expression of MIR152 mRNA]] CTD PMID:36547818 NCBI chr11:96,741,219...96,741,291
Ensembl chr11:96,741,219...96,741,291
JBrowse link
G Mir155 microRNA 155 decreases expression EXP Streptozocin results in decreased expression of MIR155 mRNA CTD PMID:27629361 NCBI chr16:84,511,028...84,511,092
Ensembl chr16:84,511,028...84,511,092
JBrowse link
G Mir18 microRNA 18 decreases expression EXP Streptozocin results in decreased expression of MIR18 mRNA CTD PMID:27629361 NCBI chr14:115,281,283...115,281,378
Ensembl chr14:115,281,283...115,281,378
JBrowse link
G Mir184 microRNA 184 decreases expression EXP Streptozocin results in decreased expression of MIR184 mRNA CTD PMID:27629361 NCBI chr 9:89,684,313...89,684,381
Ensembl chr 9:89,684,313...89,684,381
JBrowse link
G Mir188 microRNA 188 increases expression EXP Streptozocin results in increased expression of MIR188 mRNA CTD PMID:27629361 NCBI chr  X:7,114,228...7,114,295
Ensembl chr  X:7,114,228...7,114,295
JBrowse link
G Mir1894 microRNA 1894 increases expression EXP Streptozocin results in increased expression of MIR1894 mRNA CTD PMID:27629361 NCBI chr17:36,228,781...36,228,861
Ensembl chr17:36,228,781...36,228,861
JBrowse link
G Mir1896 microRNA 1896 increases expression EXP Streptozocin results in increased expression of MIR1896 mRNA CTD PMID:27629361 NCBI chr13:21,629,330...21,629,410
Ensembl chr13:21,629,330...21,629,410
JBrowse link
G Mir1901 microRNA 1901 increases expression EXP Streptozocin results in increased expression of MIR1901 mRNA CTD PMID:27629361 NCBI chr18:11,973,418...11,973,495
Ensembl chr18:11,973,418...11,973,495
JBrowse link
G Mir191 microRNA 191 increases expression EXP Streptozocin results in increased expression of MIR191 mRNA CTD PMID:27629361 NCBI chr 9:108,445,518...108,445,591
Ensembl chr 9:108,445,518...108,445,591
JBrowse link
G Mir192 microRNA 192 increases expression
multiple interactions
ISO Streptozocin results in increased expression of MIR192 mRNA
dapagliflozin inhibits the reaction [Streptozocin results in increased expression of MIR192 mRNA]
CTD PMID:37352119 NCBI chr19:6,314,874...6,314,962
Ensembl chr19:6,314,874...6,314,962
JBrowse link
G Mir1930 microRNA 1930 increases expression EXP Streptozocin results in increased expression of MIR1930 mRNA CTD PMID:27629361 NCBI chr10:77,477,058...77,477,141
Ensembl chr10:77,477,058...77,477,141
JBrowse link
G Mir1934 microRNA 1934 increases expression EXP Streptozocin results in increased expression of MIR1934 mRNA CTD PMID:27629361 NCBI chr11:69,553,869...69,553,951
Ensembl chr11:69,553,869...69,553,951
JBrowse link
G Mir194-1 microRNA 194-1 increases expression EXP Streptozocin results in increased expression of MIR194-1 mRNA CTD PMID:27629361 NCBI chr 1:185,045,516...185,045,582
Ensembl chr 1:185,045,516...185,045,582
JBrowse link
G Mir1945 microRNA 1945 increases expression EXP Streptozocin results in increased expression of MIR1945 mRNA CTD PMID:27629361 NCBI chr16:11,072,232...11,072,309
Ensembl chr16:11,072,232...11,072,309
JBrowse link
G Mir1955 microRNA 1955 increases expression EXP Streptozocin results in increased expression of MIR1955 mRNA CTD PMID:27629361 NCBI chr 2:92,022,322...92,022,419
Ensembl chr 2:92,022,322...92,022,419
JBrowse link
G Mir1962 microRNA 1962 increases expression EXP Streptozocin results in increased expression of MIR1962 mRNA CTD PMID:27629361 NCBI chr 7:135,167,891...135,168,011
Ensembl chr 7:135,167,891...135,168,011
JBrowse link
G Mir196a-1 microRNA 196a-1 decreases expression EXP Streptozocin results in decreased expression of MIR196A-1 mRNA CTD PMID:27629361 NCBI chr11:96,155,990...96,156,091
Ensembl chr11:96,155,990...96,156,091
JBrowse link
G Mir1981 microRNA 1981 increases expression EXP Streptozocin results in increased expression of MIR1981 mRNA CTD PMID:27629361 NCBI chr 1:184,554,604...184,554,685
Ensembl chr 1:184,554,604...184,554,685
JBrowse link
G Mir1982 microRNA 1982 increases expression EXP Streptozocin results in increased expression of MIR1982 mRNA CTD PMID:27629361 NCBI chr10:80,664,631...80,664,704
Ensembl chr10:80,664,631...80,664,704
JBrowse link
G Mir1b microRNA 1b increases expression EXP Streptozocin results in increased expression of MIR1B mRNA CTD PMID:27629361 NCBI chr18:10,785,446...10,785,567
Ensembl chr18:10,785,446...10,785,567
JBrowse link
G Mir200a microRNA 200a increases expression
multiple interactions
EXP Streptozocin results in increased expression of MIR200A mRNA
2,5-dihydroxybenzoic acid promotes the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of MIR200A]; [Streptozocin co-treated with Niacinamide] results in increased expression of MIR200A; Metformin promotes the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of MIR200A]
CTD PMID:27629361 PMID:37120126 NCBI chr 4:156,139,353...156,139,442
Ensembl chr 4:156,139,353...156,139,442
JBrowse link
G Mir203 microRNA 203 affects expression EXP Streptozocin affects the expression of MIR203 mRNA CTD PMID:27629361 NCBI chr12:112,097,314...112,097,389
Ensembl chr12:112,097,314...112,097,389
JBrowse link
G Mir205 microRNA 205 increases expression EXP Streptozocin results in increased expression of MIR205 mRNA CTD PMID:27629361 NCBI chr 1:193,189,771...193,189,838
Ensembl chr 1:193,189,771...193,189,838
JBrowse link
G Mir20b microRNA 20b decreases expression EXP Streptozocin results in decreased expression of MIR20B mRNA CTD PMID:27629361 NCBI chr  X:51,830,990...51,831,069
Ensembl chr  X:51,830,990...51,831,069
JBrowse link
G Mir2139 microRNA 2139 increases expression EXP Streptozocin results in increased expression of MIR2139 mRNA CTD PMID:27629361 NCBI chr 4:139,694,837...139,694,931
Ensembl chr 4:139,694,837...139,694,931
JBrowse link
G Mir216a microRNA 216a increases expression EXP Streptozocin results in increased expression of MIR216A mRNA CTD PMID:27629361 NCBI chr11:28,707,012...28,707,083
Ensembl chr11:28,707,012...28,707,083
JBrowse link
G Mir217 microRNA 217 increases expression
decreases expression
EXP
ISO
Streptozocin results in increased expression of MIR217 mRNA
Streptozocin results in decreased expression of MIR217 mRNA
CTD PMID:27629361 PMID:33283391 NCBI chr11:28,713,728...28,713,835
Ensembl chr11:28,713,728...28,713,835
JBrowse link
G Mir218-2 microRNA 218-2 increases expression EXP Streptozocin results in increased expression of MIR218-2 mRNA CTD PMID:27629361 NCBI chr11:35,507,643...35,507,752
Ensembl chr11:35,507,643...35,507,752
JBrowse link
G Mir219a-1 microRNA 219a-1 increases expression EXP Streptozocin results in increased expression of MIR219A-1 mRNA CTD PMID:27629361 NCBI chr17:34,243,957...34,244,066
Ensembl chr17:34,243,957...34,244,066
JBrowse link
G Mir21a microRNA 21a increases expression
multiple interactions
ISO Streptozocin results in increased expression of MIR21 mRNA
dapagliflozin inhibits the reaction [Streptozocin results in increased expression of MIR21 mRNA]
CTD PMID:37352119 NCBI chr11:86,474,893...86,474,984
Ensembl chr11:86,474,893...86,474,984
JBrowse link
G Mir222 microRNA 222 increases expression EXP Streptozocin results in increased expression of MIR222 mRNA CTD PMID:27629361 NCBI chr  X:19,013,132...19,013,210
Ensembl chr  X:19,013,132...19,013,210
JBrowse link
G Mir27a microRNA 27a decreases expression
multiple interactions
EXP
ISO
Streptozocin results in decreased expression of MIR27A mRNA
SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of MIR27A mRNA]
CTD PMID:27629361 NCBI chr 8:84,935,301...84,935,387
Ensembl chr 8:84,935,301...84,935,387
JBrowse link
G Mir28b microRNA 28b decreases expression EXP Streptozocin results in decreased expression of MIR28B mRNA CTD PMID:27629361 NCBI chr 8:73,743,140...73,743,219
Ensembl chr 8:73,743,140...73,743,219
JBrowse link
G Mir293 microRNA 293 increases expression EXP Streptozocin results in increased expression of MIR293 mRNA CTD PMID:27629361 NCBI chr 7:3,269,017...3,269,096
Ensembl chr 7:3,269,017...3,269,096
JBrowse link
G Mir298 microRNA 298 increases expression EXP Streptozocin results in increased expression of MIR298 mRNA CTD PMID:27629361 NCBI chr 2:174,109,297...174,109,378
Ensembl chr 2:174,109,297...174,109,378
JBrowse link
G Mir29a microRNA 29a decreases expression
multiple interactions
EXP Streptozocin results in decreased expression of MIR29A mRNA
MIR29A mRNA inhibits the reaction [Streptozocin results in decreased expression of PPARG mRNA]; MIR29A mRNA inhibits the reaction [Streptozocin results in decreased expression of PPARG protein]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of CNR1 mRNA]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of CNR1 protein]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of COL4A2 mRNA]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of JUN mRNA]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]
CTD PMID:30642005 NCBI chr 6:31,039,595...31,039,682
Ensembl chr 6:31,039,595...31,039,682
JBrowse link
G Mir29c microRNA 29c increases expression EXP Streptozocin results in increased expression of MIR29C mRNA CTD PMID:27629361 NCBI chr 1:194,719,855...194,719,942
Ensembl chr 1:194,719,855...194,719,942
JBrowse link
G Mir302a microRNA 302a increases expression EXP Streptozocin results in increased expression of MIR302A mRNA CTD PMID:27629361 NCBI chr 3:127,339,145...127,339,213
Ensembl chr 3:127,339,145...127,339,213
JBrowse link
G Mir302c microRNA 302c increases expression EXP Streptozocin results in increased expression of MIR302C mRNA CTD PMID:27629361 NCBI chr 3:127,339,012...127,339,079
Ensembl chr 3:127,339,012...127,339,079
JBrowse link
G Mir3060 microRNA 3060 decreases expression EXP Streptozocin results in decreased expression of MIR3060 mRNA CTD PMID:27629361 NCBI chr11:4,089,364...4,089,446
Ensembl chr11:4,089,364...4,089,446
JBrowse link
G Mir3063 microRNA 3063 increases expression EXP Streptozocin results in increased expression of MIR3063 mRNA CTD PMID:27629361 NCBI chr11:95,854,118...95,854,209
Ensembl chr11:95,854,118...95,854,209
JBrowse link
G Mir3067 microRNA 3067 increases expression EXP Streptozocin results in increased expression of MIR3067 mRNA CTD PMID:27629361 NCBI chr12:81,212,925...81,213,008
Ensembl chr12:81,212,925...81,213,008
JBrowse link
G Mir3075 microRNA 3075 increases expression EXP Streptozocin results in increased expression of MIR3075 mRNA CTD PMID:27629361 NCBI chr14:25,534,863...25,534,947
Ensembl chr14:25,534,863...25,534,947
JBrowse link
G Mir3078 microRNA 3078 increases expression EXP Streptozocin results in increased expression of MIR3078 mRNA CTD PMID:27629361 NCBI chr14:64,828,634...64,828,720
Ensembl chr14:64,828,634...64,828,720
JBrowse link
G Mir3083 microRNA 3083 increases expression EXP Streptozocin results in increased expression of MIR3083 mRNA CTD PMID:27629361 NCBI chr17:27,167,030...27,167,093
Ensembl chr17:27,167,030...27,167,093
JBrowse link
G Mir3086 microRNA 3086 increases expression EXP Streptozocin results in increased expression of MIR3086 mRNA CTD PMID:27629361 NCBI chr19:58,900,105...58,900,191
Ensembl chr19:58,900,105...58,900,191
JBrowse link
G Mir3088 microRNA 3088 increases expression EXP Streptozocin results in increased expression of MIR3088 mRNA CTD PMID:27629361 NCBI chr 2:28,623,290...28,623,363
Ensembl chr 2:28,623,290...28,623,363
JBrowse link
G Mir3089 microRNA 3089 increases expression EXP Streptozocin results in increased expression of MIR3089 mRNA CTD PMID:27629361 NCBI chr 2:30,611,222...30,611,305
Ensembl chr 2:30,611,222...30,611,305
JBrowse link
G Mir3090 microRNA 3090 increases expression EXP Streptozocin results in increased expression of MIR3090 mRNA CTD PMID:27629361 NCBI chr 2:133,406,628...133,406,714
Ensembl chr 2:133,406,628...133,406,714
JBrowse link
G Mir3091 microRNA 3091 increases expression EXP Streptozocin results in increased expression of MIR3091 mRNA CTD PMID:27629361 NCBI chr 2:179,899,329...179,899,404
Ensembl chr 2:179,899,329...179,899,404
JBrowse link
G Mir3093 microRNA 3093 increases expression EXP Streptozocin results in increased expression of MIR3093 mRNA CTD PMID:27629361 NCBI chr 3:88,122,478...88,122,564
Ensembl chr 3:88,122,478...88,122,564
JBrowse link
G Mir3094 microRNA 3094 increases expression EXP Streptozocin results in increased expression of MIR3094 mRNA CTD PMID:27629361 NCBI chr 4:40,993,695...40,993,758
Ensembl chr 4:40,993,695...40,993,758
JBrowse link
G Mir3095 microRNA 3095 increases expression EXP Streptozocin results in increased expression of MIR3095 mRNA CTD PMID:27629361 NCBI chr 4:58,441,012...58,441,098
Ensembl chr 4:58,441,012...58,441,098
JBrowse link
G Mir3097 microRNA 3097 increases expression EXP Streptozocin results in increased expression of MIR3097 mRNA CTD PMID:27629361 NCBI chr 5:35,178,393...35,178,459
Ensembl chr 5:35,178,393...35,178,459
JBrowse link
G Mir3102 microRNA 3102 increases expression EXP Streptozocin results in increased expression of MIR3102 mRNA CTD PMID:27629361 NCBI chr 7:100,531,513...100,531,616
Ensembl chr 7:100,531,513...100,531,616
JBrowse link
G Mir3103 microRNA 3103 decreases expression EXP Streptozocin results in decreased expression of MIR3103 mRNA CTD PMID:27629361 NCBI chr 7:127,887,541...127,887,607
Ensembl chr 7:127,887,541...127,887,607
JBrowse link
G Mir3108 microRNA 3108 increases expression EXP Streptozocin results in increased expression of MIR3108 mRNA CTD PMID:27629361 NCBI chr 8:109,663,492...109,663,570
Ensembl chr 8:109,663,492...109,663,570
JBrowse link
G Mir3109 microRNA 3109 increases expression EXP Streptozocin results in increased expression of MIR3109 mRNA CTD PMID:27629361 NCBI chr 9:69,364,226...69,364,313
Ensembl chr 9:69,364,226...69,364,313
JBrowse link
G Mir3110 microRNA 3110 increases expression EXP Streptozocin results in increased expression of MIR3110 mRNA CTD PMID:27629361 NCBI chr  X:37,299,318...37,299,397
Ensembl chr  X:37,299,318...37,299,397
JBrowse link
G Mir3113 microRNA 3113 increases expression EXP Streptozocin results in increased expression of MIR3113 mRNA CTD PMID:27629361 NCBI chr  X:150,642,558...150,642,633
Ensembl chr  X:150,642,558...150,642,633
JBrowse link
G Mir32 microRNA 32 increases expression ISO Streptozocin results in increased expression of MIR32 mRNA CTD PMID:32959695 NCBI chr 4:56,895,229...56,895,298
Ensembl chr 4:56,895,229...56,895,298
JBrowse link
G Mir322 microRNA 322 decreases expression
multiple interactions
EXP
ISO
Streptozocin results in decreased expression of MIR322 mRNA
SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of MIR322 mRNA]
CTD PMID:27629361 NCBI chr  X:52,143,132...52,143,226
Ensembl chr  X:52,143,132...52,143,226
JBrowse link
G Mir323 microRNA 323 increases expression EXP Streptozocin results in increased expression of MIR323 mRNA CTD PMID:27629361 NCBI chr12:109,678,942...109,679,027
Ensembl chr12:109,678,942...109,679,027
JBrowse link
G Mir33 microRNA 33 multiple interactions ISO [Fructose co-treated with Streptozocin] results in increased expression of MIR33A mRNA; Ghrelin inhibits the reaction [[Fructose co-treated with Streptozocin] results in increased expression of MIR33A mRNA] CTD PMID:31468622 NCBI chr15:82,082,323...82,082,391
Ensembl chr15:82,082,323...82,082,391
JBrowse link
G Mir330 microRNA 330 increases expression EXP Streptozocin results in increased expression of MIR330 mRNA CTD PMID:27629361 NCBI chr 7:18,915,390...18,915,487
Ensembl chr 7:18,915,390...18,915,487
JBrowse link
G Mir341 microRNA 341 increases expression EXP Streptozocin results in increased expression of MIR341 mRNA CTD PMID:27629361 NCBI chr12:109,577,934...109,578,029
Ensembl chr12:109,577,934...109,578,029
JBrowse link
G Mir344f microRNA Mir344f increases expression EXP Streptozocin results in increased expression of MIR344F mRNA CTD PMID:27629361 NCBI chr 7:61,695,929...61,695,996
Ensembl chr 7:61,695,929...61,695,996
JBrowse link
G Mir344g microRNA 344g increases expression EXP Streptozocin results in increased expression of MIR344G mRNA CTD PMID:27629361 NCBI chr 7:61,632,037...61,632,107
Ensembl chr 7:61,632,037...61,632,107
JBrowse link
G Mir3475 microRNA 3475 increases expression EXP Streptozocin results in increased expression of MIR3475 mRNA CTD PMID:27629361 NCBI chr  X:139,211,697...139,211,761
Ensembl chr  X:139,211,697...139,211,761
JBrowse link
G Mir375 microRNA 375 increases expression ISO Streptozocin results in increased expression of MIR375 mRNA CTD PMID:27521901 NCBI chr 1:74,939,817...74,939,880
Ensembl chr 1:74,939,817...74,939,880
JBrowse link
G Mir377 microRNA 377 multiple interactions EXP [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of MIR377]; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of MIR377 CTD PMID:38282657 NCBI chr12:109,706,944...109,707,011
Ensembl chr12:109,706,944...109,707,011
JBrowse link
G Mir379 microRNA 379 multiple interactions EXP [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of MIR379]; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of MIR379 CTD PMID:38282657 NCBI chr12:109,675,494...109,675,559
Ensembl chr12:109,675,494...109,675,559
JBrowse link
G Mir380 microRNA 380 increases expression EXP Streptozocin results in increased expression of MIR380 mRNA CTD PMID:27629361 NCBI chr12:109,678,237...109,678,297
Ensembl chr12:109,678,237...109,678,297
JBrowse link
G Mir384 microRNA 384 increases expression EXP Streptozocin results in increased expression of MIR384 mRNA CTD PMID:27629361 NCBI chr  X:104,387,888...104,387,975
Ensembl chr  X:104,387,888...104,387,975
JBrowse link
G Mir3962 microRNA 3962 decreases expression EXP Streptozocin results in decreased expression of MIR3962 mRNA CTD PMID:27629361 NCBI chr 1:194,504,309...194,504,372
Ensembl chr 1:194,504,309...194,504,372
JBrowse link
G Mir3966 microRNA 3966 increases expression EXP Streptozocin results in increased expression of MIR3966 mRNA CTD PMID:27629361 NCBI chr10:97,259,340...97,259,424
Ensembl chr10:97,259,340...97,259,424
JBrowse link
G Mir3968 microRNA 3968 decreases expression EXP Streptozocin results in decreased expression of MIR3968 mRNA CTD PMID:27629361 NCBI chr11:115,338,787...115,338,886
Ensembl chr11:115,338,787...115,338,886
JBrowse link
G Mir412 microRNA 412 increases expression EXP Streptozocin results in increased expression of MIR412 mRNA CTD PMID:27629361 NCBI chr12:109,709,723...109,709,802
Ensembl chr12:109,709,723...109,709,802
JBrowse link
G Mir421 microRNA 421 decreases expression EXP Streptozocin results in decreased expression of MIR421 mRNA CTD PMID:27629361 NCBI chr  X:102,616,527...102,616,602
Ensembl chr  X:102,616,527...102,616,602
JBrowse link
G Mir433 microRNA 433 decreases expression EXP Streptozocin results in decreased expression of MIR433 mRNA CTD PMID:27629361 NCBI chr12:109,558,149...109,558,272
Ensembl chr12:109,558,149...109,558,272
JBrowse link
G Mir434 microRNA 434 decreases expression EXP Streptozocin results in decreased expression of MIR434 mRNA CTD PMID:27629361 NCBI chr12:109,560,940...109,561,033
Ensembl chr12:109,560,940...109,561,033
JBrowse link
G Mir448 microRNA 448 multiple interactions
increases expression
ISO
EXP
SOD1 protein inhibits the reaction [Streptozocin results in increased expression of MIR448 mRNA] CTD PMID:27629361 NCBI chr  X:145,941,206...145,941,317
Ensembl chr  X:145,941,206...145,941,317
JBrowse link
G Mir450b microRNA 450b decreases expression EXP Streptozocin results in decreased expression of MIR450B mRNA CTD PMID:27629361 NCBI chr  X:52,136,874...52,136,955
Ensembl chr  X:52,136,874...52,136,955
JBrowse link
G Mir451a microRNA 451a increases expression EXP Streptozocin results in increased expression of MIR451A mRNA CTD PMID:27629361 NCBI chr11:77,963,996...77,964,067
Ensembl chr11:77,963,996...77,964,067
JBrowse link
G Mir452 microRNA 452 increases expression EXP Streptozocin results in increased expression of MIR452 mRNA CTD PMID:27629361 NCBI chr  X:71,305,830...71,305,914
Ensembl chr  X:71,305,830...71,305,914
JBrowse link
G Mir466m microRNA 466m decreases expression EXP Streptozocin results in decreased expression of MIR466M mRNA CTD PMID:27629361 NCBI chr 2:10,471,474...10,471,557
Ensembl chr 2:10,471,474...10,471,557
JBrowse link
G Mir467c microRNA 467c increases expression EXP Streptozocin results in increased expression of MIR467C mRNA CTD PMID:27629361 NCBI chr 2:10,478,742...10,478,838
Ensembl chr 2:10,478,742...10,478,838
JBrowse link
G Mir467e microRNA 467e decreases expression EXP Streptozocin results in decreased expression of MIR467E mRNA CTD PMID:27629361 NCBI chr 2:10,510,532...10,510,618
Ensembl chr 2:10,510,532...10,510,618
JBrowse link
G Mir468 microRNA 468 increases expression EXP Streptozocin results in increased expression of MIR468 mRNA CTD PMID:27629361 NCBI chr 6:81,873,580...81,873,657
Ensembl chr 6:81,873,580...81,873,657
JBrowse link
G Mir471 microRNA 471 increases expression EXP Streptozocin results in increased expression of MIR471 mRNA CTD PMID:27629361 NCBI chr  X:65,836,201...65,836,267
Ensembl chr  X:65,836,201...65,836,267
JBrowse link
G Mir490 microRNA 490 decreases expression EXP Streptozocin results in decreased expression of MIR490 mRNA CTD PMID:27629361 NCBI chr 6:36,398,677...36,398,760
Ensembl chr 6:36,398,677...36,398,760
JBrowse link
G Mir494 microRNA 494 multiple interactions EXP [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of MIR494]; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of MIR494 CTD PMID:38282657 NCBI chr12:109,681,752...109,681,836
Ensembl chr12:109,681,752...109,681,836
JBrowse link
G Mir495 microRNA 495 multiple interactions EXP [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of MIR495]; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of MIR495 CTD PMID:38282657 NCBI chr12:109,685,188...109,685,250
Ensembl chr12:109,685,188...109,685,250
JBrowse link
G Mir497 microRNA 497 multiple interactions
decreases expression
ISO MIR497 inhibits the reaction [Streptozocin results in decreased expression of MIR497 protein]; MIR497 inhibits the reaction [Streptozocin results in increased expression of USP15 mRNA]; MIR497 inhibits the reaction [Streptozocin results in increased expression of USP15 protein] CTD PMID:35478295 NCBI chr11:70,125,543...70,125,626
Ensembl chr11:70,125,543...70,125,626
JBrowse link
G Mir499 microRNA 499 decreases expression EXP Streptozocin results in decreased expression of MIR499 mRNA CTD PMID:27629361 NCBI chr 2:155,464,800...155,464,878
Ensembl chr 2:155,464,800...155,464,878
JBrowse link
G Mir504 microRNA 504 increases expression EXP Streptozocin results in increased expression of MIR504 mRNA CTD PMID:27629361 NCBI chr  X:58,143,018...58,143,096
Ensembl chr  X:58,143,018...58,143,096
JBrowse link
G Mir5103 microRNA 5103 decreases expression EXP Streptozocin results in decreased expression of MIR5103 mRNA CTD PMID:27629361 NCBI chr 1:34,472,202...34,472,280
Ensembl chr 1:34,472,202...34,472,280
JBrowse link
G Mir5107 microRNA 5107 decreases expression EXP Streptozocin results in decreased expression of MIR5107 mRNA CTD PMID:27629361 NCBI chr18:60,945,148...60,945,235
Ensembl chr18:60,945,148...60,945,235
JBrowse link
G Mir511 microRNA 511 increases expression EXP Streptozocin results in increased expression of MIR511 mRNA CTD PMID:27629361 NCBI chr 2:14,265,814...14,265,892
Ensembl chr 2:14,265,814...14,265,892
JBrowse link
G Mir5127 microRNA 5127 increases expression EXP Streptozocin results in increased expression of MIR5127 mRNA CTD PMID:27629361 NCBI chr18:82,035,225...82,035,295
Ensembl chr18:82,035,225...82,035,295
JBrowse link
G Mir544 microRNA 544 increases expression EXP Streptozocin results in increased expression of MIR544 mRNA CTD PMID:27629361 NCBI chr12:109,695,759...109,695,836
Ensembl chr12:109,695,759...109,695,836
JBrowse link
G Mir546 microRNA 546 increases expression EXP Streptozocin results in increased expression of MIR546 mRNA CTD PMID:27629361 NCBI chr10:126,834,309...126,834,429
Ensembl chr10:126,834,309...126,834,429
JBrowse link
G Mir547 microRNA 547 increases expression EXP Streptozocin results in increased expression of MIR547 mRNA CTD PMID:27629361 NCBI chr  X:67,031,980...67,032,057
Ensembl chr  X:67,031,980...67,032,057
JBrowse link
G Mir5620 microRNA 5620 increases expression EXP Streptozocin results in increased expression of MIR5620 mRNA CTD PMID:27629361 NCBI chr 7:7,301,890...7,301,945
Ensembl chr 7:7,301,890...7,301,945
JBrowse link
G Mir5621 microRNA 5621 increases expression EXP Streptozocin results in increased expression of MIR5621 mRNA CTD PMID:27629361 NCBI chr11:115,686,650...115,686,712
Ensembl chr11:115,686,650...115,686,712
JBrowse link
G Mir5625 microRNA 5625 increases expression EXP Streptozocin results in increased expression of MIR5625 mRNA CTD PMID:27629361 NCBI chr 5:30,805,280...30,805,359
Ensembl chr 5:30,805,280...30,805,359
JBrowse link
G Mir582 microRNA 582 increases expression EXP Streptozocin results in increased expression of MIR582 mRNA CTD PMID:27629361 NCBI chr13:109,461,278...109,461,358
Ensembl chr13:109,461,278...109,461,358
JBrowse link
G Mir666 microRNA 666 increases expression EXP Streptozocin results in increased expression of MIR666 mRNA CTD PMID:27629361 NCBI chr12:109,683,519...109,683,617
Ensembl chr12:109,683,519...109,683,617
JBrowse link
G Mir669j microRNA 669j increases expression EXP Streptozocin results in increased expression of MIR669J mRNA CTD PMID:27629361 NCBI chr 2:10,482,721...10,482,841
Ensembl chr 2:10,482,721...10,482,841
JBrowse link
G Mir669n microRNA 669n decreases expression EXP Streptozocin results in decreased expression of MIR669N mRNA CTD PMID:27629361 NCBI chr 3:115,773,551...115,773,604
Ensembl chr 3:115,773,551...115,773,604
JBrowse link
G Mir671 microRNA 671 increases expression EXP Streptozocin results in increased expression of MIR671 mRNA CTD PMID:27629361 NCBI chr 5:24,797,112...24,797,209
Ensembl chr 5:24,797,112...24,797,209
JBrowse link
G Mir677 microRNA 677 decreases expression EXP Streptozocin results in decreased expression of MIR677 mRNA CTD PMID:27629361 NCBI chr10:127,921,155...127,921,232
Ensembl chr10:127,921,155...127,921,232
Ensembl chr10:127,921,155...127,921,232
JBrowse link
G Mir679 microRNA 679 increases expression EXP Streptozocin results in increased expression of MIR679 mRNA CTD PMID:27629361 NCBI chr12:109,682,011...109,682,084
Ensembl chr12:109,682,011...109,682,084
JBrowse link
G Mir697 microRNA 697 decreases expression EXP Streptozocin results in decreased expression of MIR697 mRNA CTD PMID:27629361 NCBI chr 4:124,625,487...124,625,595
Ensembl chr 4:124,625,487...124,625,595
JBrowse link
G Mir702 microRNA 702 increases expression EXP Streptozocin results in increased expression of MIR702 mRNA CTD PMID:27629361 NCBI chr 5:137,020,287...137,020,395
Ensembl chr 5:137,020,287...137,020,395
JBrowse link
G Mir705 microRNA 705 decreases expression EXP Streptozocin results in decreased expression of MIR705 mRNA CTD PMID:27629361 NCBI chr 6:85,313,274...85,313,355
Ensembl chr 6:85,313,274...85,313,355
JBrowse link
G Mir718 microRNA 718 increases expression EXP Streptozocin results in increased expression of MIR718 mRNA CTD PMID:27629361 NCBI chr  X:73,067,455...73,067,542
Ensembl chr  X:73,067,455...73,067,542
JBrowse link
G Mir741 microRNA 741 increases expression EXP Streptozocin results in increased expression of MIR741 mRNA CTD PMID:27629361 NCBI chr  X:65,840,411...65,840,481
Ensembl chr  X:65,840,411...65,840,481
JBrowse link
G Mir743b microRNA 743b increases expression EXP Streptozocin results in increased expression of MIR743B mRNA CTD PMID:27629361 NCBI chr  X:65,820,862...65,820,938
Ensembl chr  X:65,820,862...65,820,938
JBrowse link
G Mir744 microRNA 744 increases expression EXP Streptozocin results in increased expression of MIR744 mRNA CTD PMID:27629361 NCBI chr11:65,625,559...65,625,658
Ensembl chr11:65,625,559...65,625,658
JBrowse link
G Mir871 microRNA 871 increases expression EXP Streptozocin results in increased expression of MIR871 mRNA CTD PMID:27629361 NCBI chr  X:65,854,034...65,854,110
Ensembl chr  X:65,854,034...65,854,110
JBrowse link
G Mir873a microRNA 873a increases expression EXP Streptozocin results in increased expression of MIR873A mRNA CTD PMID:27629361 NCBI chr 4:36,668,510...36,668,586
Ensembl chr 4:36,668,510...36,668,586
JBrowse link
G Mir875 microRNA 875 increases expression EXP Streptozocin results in increased expression of MIR875 mRNA CTD PMID:27629361 NCBI chr15:35,661,116...35,661,193
Ensembl chr15:35,661,116...35,661,193
JBrowse link
G Mir879 microRNA 879 increases expression EXP Streptozocin results in increased expression of MIR879 mRNA CTD PMID:27629361 NCBI chr 5:9,425,704...9,425,779
Ensembl chr 5:9,425,704...9,425,779
JBrowse link
G Mir93 microRNA 93 increases expression EXP Streptozocin results in increased expression of MIR93 mRNA CTD PMID:27629361 NCBI chr 5:138,163,785...138,163,872
Ensembl chr 5:138,163,785...138,163,872
JBrowse link
G Mir96 microRNA 96 increases expression EXP Streptozocin results in increased expression of MIR96 mRNA CTD PMID:27629361 NCBI chr 6:30,169,445...30,169,550
Ensembl chr 6:30,169,445...30,169,550
JBrowse link
G Mir98 microRNA 98 decreases expression EXP Streptozocin results in decreased expression of MIR98 mRNA CTD PMID:27629361 NCBI chr  X:150,696,210...150,696,317
Ensembl chr  X:150,696,210...150,696,317
JBrowse link
G Mknk2 MAP kinase-interacting serine/threonine kinase 2 increases expression ISO Streptozocin results in increased expression of MKNK2 mRNA CTD PMID:25905778 NCBI chr10:80,501,152...80,512,264
Ensembl chr10:80,501,161...80,513,946
JBrowse link
G Mme membrane metallo endopeptidase decreases expression
multiple interactions
ISO Streptozocin results in decreased expression of MME protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of MME protein]
CTD PMID:19634143 NCBI chr 3:63,202,632...63,291,134
Ensembl chr 3:63,148,958...63,293,451
JBrowse link
G Mmp13 matrix metallopeptidase 13 increases expression
multiple interactions
ISO Streptozocin results in increased expression of MMP13 mRNA
esculetin inhibits the reaction [Streptozocin results in increased expression of MMP13 mRNA]
CTD PMID:21450970 NCBI chr 9:7,272,514...7,283,333
Ensembl chr 9:7,272,514...7,283,331
JBrowse link
G Mmp1b matrix metallopeptidase 1b (interstitial collagenase) increases expression ISO Streptozocin results in increased expression of MMP1 protein CTD PMID:35993117 NCBI chr 9:7,367,670...7,388,026
Ensembl chr 9:7,368,239...7,388,047
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
increases expression
decreases expression
increases activity
decreases secretion
ISO
EXP
PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of MMP2 mRNA]
Streptozocin results in decreased expression of MMP2 mRNA; Streptozocin results in decreased expression of MMP2 protein
benazepril inhibits the reaction [Streptozocin results in decreased expression of MMP2 mRNA]; benazepril inhibits the reaction [Streptozocin results in decreased expression of MMP2 protein]; dapagliflozin inhibits the reaction [Streptozocin results in increased expression of MMP2 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of MMP2 protein]; Olive Oil inhibits the reaction [Streptozocin results in increased activity of MMP2 protein]; rhapontin inhibits the reaction [Streptozocin results in increased expression of MMP2 mRNA]; Tropisetron inhibits the reaction [Streptozocin results in decreased expression of MMP2 mRNA]
Streptozocin results in increased expression of MMP2 mRNA; Streptozocin results in increased expression of MMP2 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Raloxifene Hydrochloride inhibits the reaction [Streptozocin results in decreased secretion of MMP2 protein]]; CEBPB protein inhibits the reaction [Streptozocin results in decreased expression of MMP2 protein]; ESR2 protein affects the reaction [Raloxifene Hydrochloride inhibits the reaction [Streptozocin results in decreased secretion of MMP2 protein]]; Raloxifene Hydrochloride inhibits the reaction [Streptozocin results in decreased expression of MMP2 mRNA]; Raloxifene Hydrochloride inhibits the reaction [Streptozocin results in decreased secretion of MMP2 protein]; Valsartan inhibits the reaction [Streptozocin results in decreased expression of MMP2 protein]
CTD PMID:16732983 PMID:20446767 PMID:20821936 PMID:23471663 PMID:25246140 More... NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048
JBrowse link
G Mmp3 matrix metallopeptidase 3 increases expression
multiple interactions
decreases expression
EXP
ISO
Streptozocin results in increased expression of MMP3 mRNA
PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of MMP3 mRNA]
Streptozocin results in decreased expression of MMP3 mRNA
CTD PMID:18246672 PMID:20446767 NCBI chr 9:7,445,845...7,455,975
Ensembl chr 9:7,445,822...7,455,975
JBrowse link
G Mmp7 matrix metallopeptidase 7 multiple interactions
increases expression
ISO
EXP
PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of MMP7 mRNA]
[Streptozocin co-treated with Dietary Fats] results in increased expression of MMP7 mRNA
CTD PMID:20446767 PMID:29127188 NCBI chr 9:7,692,095...7,699,587
Ensembl chr 9:7,692,091...7,699,587
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
increases expression
increases activity
decreases expression
ISO
EXP
PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of MMP9 mRNA]
Streptozocin results in increased expression of MMP9 mRNA; Streptozocin results in increased expression of MMP9 protein
[Streptozocin co-treated with Tobacco Smoke Pollution] results in increased expression of MMP9 protein; idebenone inhibits the reaction [Streptozocin results in increased expression of MMP9 protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of MMP9 protein]; Olive Oil inhibits the reaction [Streptozocin results in increased activity of MMP9 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of MMP9 mRNA]; Rosiglitazone inhibits the reaction [Streptozocin deficiency results in increased expression of MMP9 mRNA]; Simvastatin inhibits the reaction [Streptozocin results in increased expression of MMP9 mRNA]; Tropisetron inhibits the reaction [Streptozocin results in decreased expression of MMP9 mRNA]
[Dietary Fats co-treated with Streptozocin] results in increased expression of MMP9 mRNA; formononetin inhibits the reaction [Streptozocin results in increased expression of MMP9 mRNA]; formononetin inhibits the reaction [Streptozocin results in increased expression of MMP9 protein]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of MMP9 mRNA]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Streptozocin promotes the reaction [JUN protein binds to MMP9 promoter]]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Streptozocin promotes the reaction [RELA protein binds to MMP9 promoter]]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Streptozocin results in increased expression of MMP9 mRNA]; SIRT1 protein inhibits the reaction [Streptozocin promotes the reaction [PARP1 protein binds to MMP9 promoter]]; Streptozocin promotes the reaction [JUN protein binds to MMP9 promoter]; Streptozocin promotes the reaction [PARP1 protein binds to MMP9 promoter]; Streptozocin promotes the reaction [RELA protein binds to MMP9 promoter]
CTD PMID:19236438 PMID:19820293 PMID:20446767 PMID:22191573 PMID:25246140 More... NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
JBrowse link
G Mmrn1 multimerin 1 increases expression ISO Streptozocin results in increased expression of MMRN1 protein CTD PMID:21450970 NCBI chr 6:60,921,301...60,966,362
Ensembl chr 6:60,901,960...60,966,362
JBrowse link
G Mogat1 monoacylglycerol O-acyltransferase 1 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of MOGAT1 mRNA CTD PMID:29127188 NCBI chr 1:78,487,697...78,597,882
Ensembl chr 1:78,487,628...78,514,810
JBrowse link
G Mpg N-methylpurine-DNA glycosylase affects response to substance EXP MPG protein affects the susceptibility to Streptozocin CTD PMID:17098815 NCBI chr11:32,176,505...32,182,702
Ensembl chr11:32,176,505...32,182,700
JBrowse link
G Mpo myeloperoxidase multiple interactions
increases activity
EXP
ISO
[Streptozocin co-treated with Dextran Sulfate] results in increased activity of MPO protein; bisphenol A diglycidyl ether inhibits the reaction [Lisinopril inhibits the reaction [Streptozocin results in increased activity of MPO protein]]; bisphenol A diglycidyl ether inhibits the reaction [Telmisartan inhibits the reaction [Streptozocin results in increased activity of MPO protein]]; Donepezil inhibits the reaction [Streptozocin results in increased activity of MPO protein]; Lisinopril inhibits the reaction [Streptozocin results in increased activity of MPO protein]; Telmisartan inhibits the reaction [Streptozocin results in increased activity of MPO protein]
Streptozocin results in increased expression of and results in increased activity of MPO protein
CTD PMID:23060470 PMID:24924950 PMID:34039237 PMID:34964214 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239
JBrowse link
G Mpped1 metallophosphoesterase domain containing 1 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of MPPED1 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of MPPED1 mRNA] CTD PMID:33484791 NCBI chr15:83,656,256...83,742,688
Ensembl chr15:83,663,668...83,742,695
JBrowse link
G Mpz myelin protein zero multiple interactions
decreases expression
ISO 20-alpha-Dihydroprogesterone inhibits the reaction [Streptozocin results in decreased expression of MPZ mRNA]; Progesterone inhibits the reaction [Streptozocin results in decreased expression of MPZ mRNA] CTD PMID:17187935 NCBI chr 1:170,978,282...170,988,699
Ensembl chr 1:170,978,280...170,988,699
JBrowse link
G Mrc1 mannose receptor, C type 1 decreases expression
multiple interactions
EXP Streptozocin results in decreased expression of MRC1 mRNA
AM6545 inhibits the reaction [Streptozocin results in decreased expression of MRC1 mRNA]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in decreased expression of MRC1 mRNA]]; Perindopril inhibits the reaction [Streptozocin results in decreased expression of MRC1 mRNA]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in decreased expression of MRC1 mRNA]]
CTD PMID:30184259 NCBI chr 2:14,234,225...14,336,834
Ensembl chr 2:14,234,203...14,336,868
JBrowse link
G Mroh6 maestro heat-like repeat family member 6 multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of MROH6 mRNA CTD PMID:33484791 NCBI chr15:75,753,085...75,762,544
Ensembl chr15:75,755,986...75,760,619
JBrowse link
G Mrpl14 mitochondrial ribosomal protein L14 affects expression EXP Streptozocin affects the expression of MRPL14 mRNA CTD PMID:18583417 NCBI chr17:45,991,689...46,009,421
Ensembl chr17:45,997,248...46,009,421
JBrowse link
G Mrpl18 mitochondrial ribosomal protein L18 affects expression EXP Streptozocin affects the expression of MRPL18 mRNA CTD PMID:18583417 NCBI chr17:13,130,232...13,136,674
Ensembl chr17:13,130,236...13,135,232
JBrowse link
G Mrpl42 mitochondrial ribosomal protein L42 affects expression EXP Streptozocin affects the expression of MRPL42 mRNA CTD PMID:18583417 NCBI chr10:95,316,667...95,337,811
Ensembl chr10:95,316,667...95,337,802
JBrowse link
G Mrps7 mitchondrial ribosomal protein S7 affects expression EXP Streptozocin affects the expression of MRPS7 mRNA CTD PMID:18583417 NCBI chr11:115,494,966...115,498,862
Ensembl chr11:115,494,751...115,498,862
JBrowse link
G Ms4a3 membrane-spanning 4-domains, subfamily A, member 3 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of MS4A3 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of MS4A3 mRNA] CTD PMID:33484791 NCBI chr19:11,606,863...11,618,215
Ensembl chr19:11,606,860...11,618,215
JBrowse link
G Ms4a6c membrane-spanning 4-domains, subfamily A, member 6C multiple interactions ISO [Resveratrol co-treated with Streptozocin] results in increased expression of MS4A6A mRNA CTD PMID:25905778 NCBI chr19:11,446,718...11,464,433
Ensembl chr19:11,446,730...11,459,556
JBrowse link
G Msln mesothelin multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of MSLN mRNA CTD PMID:29127188 NCBI chr17:25,967,587...25,973,352
Ensembl chr17:25,967,587...25,973,352
JBrowse link
G Mt1 metallothionein 1 increases expression
decreases expression
multiple interactions
ISO Streptozocin results in increased expression of MT1A mRNA
Streptozocin results in decreased expression of MT1A mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of MT1A mRNA]; Zinc promotes the reaction [Streptozocin results in increased expression of MT1A mRNA]
CTD PMID:16684804 PMID:19369054 PMID:24927960 NCBI chr 8:94,905,214...94,906,955
Ensembl chr 8:94,905,710...94,906,955
JBrowse link
G Mt2 metallothionein 2 decreases expression ISO Streptozocin results in decreased expression of MT2A mRNA CTD PMID:24927960 NCBI chr 8:94,899,246...94,900,195
Ensembl chr 8:94,899,292...94,900,196
JBrowse link
G Mt3 metallothionein 3 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of MT3 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of MT3 mRNA] CTD PMID:33484791 NCBI chr 8:94,879,235...94,880,776
Ensembl chr 8:94,879,235...94,880,774
JBrowse link
G Mthfr methylenetetrahydrofolate reductase multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of MTHFR mRNA CTD PMID:29127188 NCBI chr 4:148,123,534...148,144,019
Ensembl chr 4:148,123,534...148,144,008
JBrowse link
G Mtmr7 myotubularin related protein 7 multiple interactions ISO [resveratrol co-treated with Streptozocin] results in decreased expression of MTMR7 mRNA CTD PMID:25905778 NCBI chr 8:41,003,184...41,088,210
Ensembl chr 8:41,004,136...41,087,840
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions
decreases expression
increases expression
increases phosphorylation
ISO
EXP
Resveratrol inhibits the reaction [Streptozocin results in decreased expression of MTOR mRNA]; Streptozocin results in decreased expression of and results in decreased phosphorylation of MTOR protein
5-Methoxypsoralen inhibits the reaction [Streptozocin results in increased expression of MTOR protein modified form]; [Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of MTOR protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of MTOR protein]; Tadalafil inhibits the reaction [Streptozocin results in increased expression of MTOR protein modified form]
streptozocin increases increases phosphorylation of Mtor protein in heart
CTD
RGD
PMID:26071184 PMID:33484791 PMID:34428446 PMID:38706688 PMID:36044268 RGD:156430337 NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140
JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase decreases activity
multiple interactions
ISO
EXP
Streptozocin results in decreased activity of MTR protein
[Streptozocin co-treated with Dietary Fats] results in decreased expression of MTR mRNA
CTD PMID:16835399 PMID:29127188 NCBI chr13:12,196,217...12,273,090
Ensembl chr13:12,197,598...12,272,999
JBrowse link
G Myd88 myeloid differentiation primary response gene 88 multiple interactions
increases expression
EXP
ISO
[Dietary Fats co-treated with Streptozocin] results in increased expression of MYD88 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of MYD88 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of MYD88 protein; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of MYD88 mRNA]; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of MYD88 protein]; esculetin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of MYD88 mRNA]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of MYD88 mRNA]
myrtenol inhibits the reaction [Streptozocin results in increased expression of MYD88 mRNA]
CTD PMID:27769711 PMID:34477272 PMID:34610774 PMID:37482253 NCBI chr 9:119,165,000...119,169,084
Ensembl chr 9:119,165,000...119,170,477
JBrowse link
G Myh3 myosin, heavy polypeptide 3, skeletal muscle, embryonic increases expression
multiple interactions
ISO Streptozocin results in increased expression of MYH3 mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of MYH3 mRNA]
CTD PMID:16684804 NCBI chr11:66,969,101...66,993,117
Ensembl chr11:66,969,126...66,993,112
JBrowse link
G Myh6 myosin, heavy polypeptide 6, cardiac muscle, alpha multiple interactions
decreases expression
ISO Enalapril inhibits the reaction [Streptozocin results in decreased expression of MYH6 mRNA]; Enalapril inhibits the reaction [Streptozocin results in decreased expression of MYH6 protein]; Losartan inhibits the reaction [Streptozocin results in decreased expression of MYH6 mRNA]; Losartan inhibits the reaction [Streptozocin results in decreased expression of MYH6 protein]
Streptozocin results in decreased expression of MYH6 mRNA; Streptozocin results in decreased expression of MYH6 protein
CTD PMID:15362513 NCBI chr14:55,179,378...55,205,553
Ensembl chr14:55,179,378...55,204,384
JBrowse link
G Myh7 myosin, heavy polypeptide 7, cardiac muscle, beta multiple interactions
increases expression
ISO Enalapril inhibits the reaction [Streptozocin results in increased expression of MYH7 mRNA]; Enalapril inhibits the reaction [Streptozocin results in increased expression of MYH7 protein]; Losartan inhibits the reaction [Streptozocin results in increased expression of MYH7 mRNA]; Losartan inhibits the reaction [Streptozocin results in increased expression of MYH7 protein]
Streptozocin results in increased expression of MYH7 mRNA; Streptozocin results in increased expression of MYH7 protein
CTD PMID:15362513 NCBI chr14:55,208,141...55,232,083
Ensembl chr14:55,208,141...55,232,083
JBrowse link
G Naglu alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB) increases activity
multiple interactions
ISO Streptozocin results in increased activity of NAGLU protein
Metformin inhibits the reaction [Streptozocin results in increased activity of NAGLU protein]
CTD PMID:33639173 NCBI chr11:100,960,918...100,968,483
Ensembl chr11:100,960,838...100,968,498
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase increases expression
multiple interactions
ISO Streptozocin results in increased expression of NAMPT mRNA
[Streptozocin co-treated with Dietary Fats] results in increased expression of NAMPT protein; Rosiglitazone inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NAMPT protein]
CTD PMID:25905778 PMID:29441829 NCBI chr12:32,870,334...32,903,368
Ensembl chr12:32,869,544...32,903,348
JBrowse link
G Nat8 N-acetyltransferase 8 (GCN5-related) multiple interactions
increases expression
ISO [resveratrol co-treated with Streptozocin] results in decreased expression of NAT8 mRNA
Streptozocin results in increased expression of NAT8 mRNA
CTD PMID:25905778 NCBI chr 6:85,807,369...85,813,839
Ensembl chr 6:85,807,370...85,809,064
JBrowse link
G Nat8f3 N-acetyltransferase 8 (GCN5-related) family member 3 increases expression ISO Streptozocin results in increased expression of NAT8F3 mRNA CTD PMID:25905778 NCBI chr 6:85,737,613...85,742,726
Ensembl chr 6:85,709,495...85,742,736
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 increases expression
multiple interactions
EXP
ISO
Streptozocin results in increased expression of NCF1 protein
telmisartan inhibits the reaction [Streptozocin results in increased expression of NCF1 protein]; terutroban inhibits the reaction [Streptozocin results in increased expression of NCF1 protein]
4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of NCF1 mRNA]; 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of NCF1 protein]; [Streptozocin co-treated with Cholesterol, Dietary] results in increased expression of NCF1 protein; Cholesterol, Dietary promotes the reaction [Streptozocin results in increased expression of NCF1 protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Cholesterol, Dietary] results in increased expression of NCF1 protein]
Streptozocin results in increased expression of NCF1 mRNA; Streptozocin results in increased expression of NCF1 protein
CTD PMID:14871415 PMID:16380483 PMID:20399799 PMID:21381899 NCBI chr 5:134,248,907...134,258,479
Ensembl chr 5:134,248,907...134,258,479
JBrowse link
G Ncf2 neutrophil cytosolic factor 2 increases expression
multiple interactions
EXP
ISO
Streptozocin results in increased expression of NCF2 protein
telmisartan inhibits the reaction [Streptozocin results in increased expression of NCF2 protein]
[Carbamazepine affects the susceptibility to [Dietary Fats co-treated with Streptozocin]] which results in decreased expression of NCF2 mRNA
CTD PMID:21381899 PMID:35786680 NCBI chr 1:152,675,904...152,712,743
Ensembl chr 1:152,675,945...152,712,742
JBrowse link
G Ndst1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 multiple interactions
decreases expression
ISO Enalapril inhibits the reaction [Streptozocin results in decreased expression of NDST1 protein]; Losartan inhibits the reaction [Streptozocin results in decreased expression of NDST1 protein]
Streptozocin results in decreased expression of NDST1 mRNA; Streptozocin results in decreased expression of NDST1 protein
CTD PMID:15793251 NCBI chr18:60,817,566...60,907,465
Ensembl chr18:60,817,566...60,881,722
JBrowse link
G Ndufa10 NADH:ubiquinone oxidoreductase subunit A10 multiple interactions
increases expression
ISO Trientine inhibits the reaction [Streptozocin results in increased expression of NDUFA10 protein] CTD PMID:21136691 NCBI chr 1:92,367,208...92,401,547
Ensembl chr 1:92,366,732...92,401,582
JBrowse link
G Ndufa8 NADH:ubiquinone oxidoreductase subunit A8 affects expression EXP Streptozocin affects the expression of NDUFA8 mRNA CTD PMID:18583417 NCBI chr 2:35,926,336...35,939,350
Ensembl chr 2:35,926,338...35,939,418
JBrowse link
G Ndufab1 NADH:ubiquinone oxidoreductase subunit AB1 increases expression
multiple interactions
ISO Streptozocin results in increased expression of NDUFAB1 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of NDUFAB1 protein]
CTD PMID:19634143 NCBI chr 7:121,686,038...121,701,071
Ensembl chr 7:121,684,626...121,701,109
JBrowse link
G Ndufs2 NADH:ubiquinone oxidoreductase core subunit S2 multiple interactions
increases expression
ISO Trientine inhibits the reaction [Streptozocin results in increased expression of NDUFS2 protein] CTD PMID:19634143 NCBI chr 1:171,062,426...171,078,956
Ensembl chr 1:171,062,422...171,078,957
JBrowse link
G Ndufs4 NADH:ubiquinone oxidoreductase core subunit S4 multiple interactions
increases expression
ISO Trientine inhibits the reaction [Streptozocin results in increased expression of NDUFS4 protein] CTD PMID:19634143 NCBI chr13:114,424,331...114,524,630
Ensembl chr13:114,424,331...114,524,794
JBrowse link
G Ndufs8 NADH:ubiquinone oxidoreductase core subunit S8 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of NDUFS8 mRNA; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NDUFS8 mRNA]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NDUFS8 mRNA] CTD PMID:37337224 NCBI chr19:3,958,863...3,962,774
Ensembl chr19:3,958,863...3,962,774
JBrowse link
G Ndufv2 NADH:ubiquinone oxidoreductase core subunit V2 increases expression
multiple interactions
ISO Streptozocin results in increased expression of NDUFV2 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of NDUFV2 protein]
CTD PMID:19634143 NCBI chr17:66,385,790...66,408,554
Ensembl chr17:66,385,633...66,408,554
JBrowse link
G Nefh neurofilament, heavy polypeptide decreases expression ISO Streptozocin results in decreased expression of NEFH protein CTD PMID:30583000 NCBI chr11:4,888,754...4,898,064
Ensembl chr11:4,888,754...4,898,064
JBrowse link
G Nes nestin multiple interactions
decreases expression
ISO INS protein inhibits the reaction [Streptozocin results in decreased expression of NES mRNA]
Streptozocin results in decreased expression of NES mRNA; Streptozocin results in decreased expression of NES protein
CTD PMID:19388005 NCBI chr 3:87,878,400...87,887,758
Ensembl chr 3:87,878,385...87,887,758
JBrowse link
G Neu2 neuraminidase 2 increases expression ISO Streptozocin results in increased expression of NEU2 mRNA CTD PMID:25905778 NCBI chr 1:87,501,749...87,525,567
Ensembl chr 1:87,437,611...87,525,567
JBrowse link
G Neurod1 neurogenic differentiation 1 multiple interactions
decreases expression
EXP [Streptozocin co-treated with bisphenol A] results in decreased expression of NEUROD1 mRNA; octylphenol inhibits the reaction [Streptozocin results in decreased expression of NEUROD1 mRNA]; Streptozocin inhibits the reaction [Ethinyl Estradiol results in increased expression of NEUROD1 mRNA]; Streptozocin inhibits the reaction [octylphenol results in increased expression of NEUROD1 mRNA] CTD PMID:24781736 PMID:29935216 NCBI chr 2:79,282,981...79,286,980
Ensembl chr 2:79,282,865...79,287,095
JBrowse link
G Nfatc1 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1 increases expression
multiple interactions
EXP Streptozocin results in increased expression of NFATC1 mRNA; Streptozocin results in increased expression of NFATC1 protein
formononetin inhibits the reaction [Streptozocin results in increased expression of NFATC1 mRNA]; formononetin inhibits the reaction [Streptozocin results in increased expression of NFATC1 protein]
CTD PMID:35315182 NCBI chr18:80,649,418...80,756,286
Ensembl chr18:80,649,420...80,756,286
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 multiple interactions
increases expression
affects response to substance
decreases expression
affects localization
increases activity
increases expression
ISO
EXP
2-tert-butylhydroquinone inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of NFE2L2 mRNA]; 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of NFE2L2 protein]; 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of NFE2L2 protein]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of NFE2L2 protein; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of NFE2L2 mRNA; [Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 protein]; [Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of NFE2L2 mRNA; [Streptozocin co-treated with Niacinamide] results in decreased expression of NFE2L2 protein; [Zinc co-treated with Selenium] inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; allyl isothiocyanate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [NFE2L2 protein inhibits the reaction [Streptozocin results in increased expression of USP15 protein]]; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of NFE2L2 mRNA]; chromium histidinate inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; Curcumin inhibits the reaction [Streptozocin affects the localization of NFE2L2 protein]; dapagliflozin inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; diallyl trisulfide inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; Dimethyl Fumarate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; G6PD protein promotes the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; G6PD protein promotes the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of NFE2L2 mRNA]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of NFE2L2 protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of NFE2L2 mRNA]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of NFE2L2 mRNA]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of NFE2L2 mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 protein]; Metformin inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; NFE2L2 protein inhibits the reaction [Streptozocin results in decreased expression of G6PD mRNA]; NFE2L2 protein inhibits the reaction [Streptozocin results in decreased expression of G6PD protein]; NFE2L2 protein inhibits the reaction [Streptozocin results in increased expression of USP15 protein]; palbinone inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; picolinic acid inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; Plant Extracts inhibits the reaction [Streptozocin affects the localization of NFE2L2 protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of NFE2L2 mRNA]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of NFE2L2 protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; Resveratrol promotes the reaction [Streptozocin affects the localization of NFE2L2 protein]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; Streptozocin results in decreased expression of and results in decreased phosphorylation of NFE2L2 protein; STUB1 inhibits the reaction [Streptozocin results in decreased expression of and results in decreased phosphorylation of NFE2L2 protein]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; USP15 protein inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; USP15 protein inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]
Streptozocin results in increased expression of NFE2L2 mRNA; Streptozocin results in increased expression of NFE2L2 protein
NFE2L2 protein affects the susceptibility to Streptozocin
Streptozocin results in decreased expression of NFE2L2 mRNA; Streptozocin results in decreased expression of NFE2L2 protein
2,5-dihydroxybenzoic acid promotes the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of NFE2L2 protein]; [Acrylamide co-treated with Streptozocin] results in decreased expression of NFE2L2 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of NFE2L2 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of NFE2L2 protein; [NFE2L2 protein mutant form co-treated with Streptozocin] results in increased abundance of 3-Hydroxybutyric Acid; [NFE2L2 protein mutant form co-treated with Streptozocin] results in increased abundance of Glucose; [NFE2L2 protein mutant form co-treated with Streptozocin] results in increased abundance of Triglycerides; [Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 protein; [Streptozocin co-treated with Niacinamide] results in increased expression of NFE2L2 protein; [Streptozocin co-treated with sulforaphane] results in increased expression of NFE2L2; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of NFE2L2 mRNA]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of NFE2L2 protein]; Metformin promotes the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of NFE2L2 protein]; NFE2L2 protein affects the reaction [Streptozocin results in decreased abundance of Glycogen]; pterostilbene inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; pterostilbene inhibits the reaction [Streptozocin results in decreased phosphorylation of and affects the localization of NFE2L2 protein]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 mRNA]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 protein]; Streptozocin results in decreased expression of and results in decreased phosphorylation of NFE2L2 protein; Streptozocin results in decreased phosphorylation of and affects the localization of NFE2L2 protein; sulforaphane inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 mRNA]; sulforaphane inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 protein]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of and results in decreased phosphorylation of NFE2L2 protein]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]
Streptozocin results in increased activity of NFE2L2 protein
streptozocin increases expression of Nfe2l2 protein in heart
CTD
RGD
PMID:20086057 PMID:20399799 PMID:21439372 PMID:21799698 PMID:22023613 More... RGD:156430337 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 increases activity
multiple interactions
ISO
EXP
Streptozocin results in increased activity of NFKB1 protein
[Dietary Fats co-treated with Streptozocin] results in increased expression of NFKB1 mRNA; [Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NFKB1 protein]; [Streptozocin co-treated with Dietary Fats] results in increased expression of NFKB1 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of NFKB1 protein; Bilirubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NFKB1 mRNA]; Dimethyl Fumarate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NFKB1 protein]; Fungal Polysaccharides inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of NFKB1 mRNA]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NFKB1 protein]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of NFKB1 mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NFKB1 protein]
[Streptozocin co-treated with Dietary Fats] results in increased expression of NFKB1 mRNA; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NFKB1 mRNA]
CTD PMID:15284299 PMID:31100278 PMID:34610774 PMID:36999408 PMID:37054934 NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha increases expression
multiple interactions
decreases expression
increases phosphorylation
increases degradation
ISO
EXP
Streptozocin results in increased expression of NFKBIA mRNA; Streptozocin results in increased expression of NFKBIA protein
arjunolic acid inhibits the reaction [Streptozocin results in decreased expression of NFKBIA protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased phosphorylation of NFKBIA protein]; benazepril inhibits the reaction [Streptozocin results in decreased expression of NFKBIA mRNA]; bisphenol A diglycidyl ether inhibits the reaction [Calcitriol inhibits the reaction [Streptozocin results in decreased expression of NFKBIA protein]]; Calcitriol inhibits the reaction [Streptozocin results in decreased expression of NFKBIA protein]; chromium histidinate inhibits the reaction [Streptozocin results in decreased expression of NFKBIA protein]; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in decreased expression of NFKBIA mRNA]; fasudil inhibits the reaction [Streptozocin results in decreased expression of NFKBIA protein]; IGF2R protein modified form promotes the reaction [Streptozocin results in decreased expression of NFKBIA protein modified form]; picolinic acid inhibits the reaction [Streptozocin results in decreased expression of NFKBIA protein]; Quercetin inhibits the reaction [Streptozocin results in increased degradation of NFKBIA protein]; Streptozocin promotes the reaction [IGF2R protein modified form results in decreased expression of NFKBIA protein modified form]; vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of NFKBIA mRNA]
Streptozocin results in decreased expression of NFKBIA mRNA; Streptozocin results in decreased expression of NFKBIA protein; Streptozocin results in decreased expression of NFKBIA protein modified form
CTD PMID:15284299 PMID:15976052 PMID:16177186 PMID:16684804 PMID:17900838 More... NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432
JBrowse link
G Nfkbib nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of NFKBIB mRNA; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NFKBIB mRNA] CTD PMID:34610774 NCBI chr 7:28,457,676...28,466,069
Ensembl chr 7:28,457,676...28,466,937
JBrowse link
G Nfkbiz nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of NFKBIZ mRNA CTD PMID:25905778 NCBI chr16:55,631,740...55,659,018
Ensembl chr16:55,631,738...55,659,262
JBrowse link
G Ngf nerve growth factor multiple interactions
affects localization
increases expression
decreases expression
ISO 4-methylcatechol inhibits the reaction [Streptozocin results in decreased expression of NGF protein]; Butylated Hydroxytoluene inhibits the reaction [Streptozocin results in increased expression of NGF mRNA]; epalrestat inhibits the reaction [Streptozocin results in decreased expression of NGF protein]; sorbinil inhibits the reaction [Streptozocin results in increased expression of NGF mRNA]; Vitamin B 12 inhibits the reaction [Streptozocin results in decreased expression of NGF protein]
Streptozocin affects the localization of NGF protein
CTD PMID:8195800 PMID:9628756 PMID:9748608 PMID:12031555 PMID:38049026 NCBI chr 3:102,377,235...102,428,329
Ensembl chr 3:102,377,235...102,428,329
JBrowse link
G Nim1k NIM1 serine/threonine protein kinase multiple interactions ISO [resveratrol co-treated with Streptozocin] results in decreased expression of NIM1K mRNA CTD PMID:25905778 NCBI chr13:120,171,630...120,217,418
Ensembl chr13:120,171,630...120,217,418
JBrowse link
G Nipsnap2 nipsnap homolog 2 affects expression EXP Streptozocin affects the expression of NIPSNAP2 mRNA CTD PMID:18583417 NCBI chr 5:129,802,080...129,835,391
Ensembl chr 5:129,802,127...129,835,391
JBrowse link
G Nkap NFKB activating protein multiple interactions ISO Streptozocin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of NKAP mRNA] CTD PMID:30611788 NCBI chr  X:36,390,416...36,414,399
Ensembl chr  X:36,390,448...36,414,399
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions
increases expression
ISO
EXP
[Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NLRP3 protein]; [Streptozocin co-treated with Dietary Fats] results in increased expression of NLRP3 protein; Allopurinol inhibits the reaction [Streptozocin results in increased expression of NLRP3 mRNA]; Allopurinol inhibits the reaction [Streptozocin results in increased expression of NLRP3 protein]; Dimethyl Fumarate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NLRP3 protein]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NLRP3 protein]; myrtenol inhibits the reaction [Streptozocin results in increased expression of NLRP3 mRNA]; palbinone inhibits the reaction [Streptozocin results in increased expression of NLRP3 protein]; Quercetin inhibits the reaction [Streptozocin results in increased expression of NLRP3 mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of NLRP3 protein]; scutellarin inhibits the reaction [Streptozocin results in increased expression of NLRP3 protein]
Streptozocin results in increased expression of NLRP3 mRNA; Streptozocin results in increased expression of NLRP3 protein
[Dietary Fats co-treated with Streptozocin] results in increased expression of NLRP3 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of NLRP3 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of NLRP3 protein; aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NLRP3 protein]; loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of NLRP3 mRNA]; loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of NLRP3 protein]; NLRP3 protein promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of TJP1 protein]; NLRP3 protein promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of TJP2 protein]; NLRP3 protein promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased activity of CASP1 protein]
CTD PMID:23647015 PMID:27783111 PMID:32202043 PMID:34477272 PMID:35961541 More... NCBI chr11:59,432,395...59,457,781
Ensembl chr11:59,432,394...59,457,782
JBrowse link
G Nmrk1 nicotinamide riboside kinase 1 increases expression
multiple interactions
ISO Streptozocin results in increased expression of NMRK1 mRNA
[resveratrol co-treated with Streptozocin] results in decreased expression of NMRK1 mRNA
CTD PMID:25905778 NCBI chr19:18,609,380...18,629,555
Ensembl chr19:18,609,314...18,629,792
JBrowse link
G Nnt nicotinamide nucleotide transhydrogenase multiple interactions
increases expression
ISO Trientine inhibits the reaction [Streptozocin results in increased expression of NNT protein] CTD PMID:19634143 NCBI chr13:119,472,063...119,545,793
Ensembl chr13:119,471,984...119,545,533
Ensembl chr13:119,471,984...119,545,533
JBrowse link
G Nos1 nitric oxide synthase 1, neuronal multiple interactions
decreases expression
increases expression
ISO
EXP
1-hexacosanol inhibits the reaction [Streptozocin results in decreased expression of NOS1 mRNA]; 1-hexacosanol inhibits the reaction [Streptozocin results in decreased expression of NOS1 protein]; [Sildenafil Citrate co-treated with resveratrol] inhibits the reaction [Streptozocin results in decreased expression of NOS1 protein]; resveratrol inhibits the reaction [Streptozocin results in decreased expression of NOS1 protein]
Streptozocin results in decreased expression of NOS1 mRNA; Streptozocin results in decreased expression of NOS1 protein
Streptozocin results in increased expression of NOS1 mRNA
Acrylamide inhibits the reaction [Streptozocin results in increased expression of NOS1 mRNA]
CTD PMID:18528636 PMID:26006044 PMID:34896238 NCBI chr 5:118,004,904...118,096,905
Ensembl chr 5:117,919,097...118,096,905
JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions
increases activity
increases expression
EXP
ISO
[bisphenol A co-treated with Streptozocin] results in decreased expression of NOS2 protein; [Ethinyl Estradiol co-treated with Streptozocin] results in decreased expression of NOS2 protein; [octylphenol co-treated with Streptozocin] results in decreased expression of NOS2 protein; [Streptozocin co-treated with bisphenol A] results in increased expression of NOS2 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of NOS2 mRNA; AM6545 inhibits the reaction [Streptozocin results in increased expression of NOS2 mRNA]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in increased expression of NOS2 mRNA]]; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NOS2 mRNA]; Perindopril inhibits the reaction [Streptozocin results in increased expression of NOS2 mRNA]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in increased expression of NOS2 mRNA]]; Quercetin inhibits the reaction [Streptozocin results in increased expression of NOS2 protein]; Sodium Selenite inhibits the reaction [Streptozocin results in increased activity of NOS2 protein]; Sodium Selenite inhibits the reaction [Streptozocin results in increased expression of NOS2 mRNA]; Streptozocin inhibits the reaction [Ethinyl Estradiol results in decreased expression of NOS2 mRNA]; Streptozocin inhibits the reaction [octylphenol results in decreased expression of NOS2 mRNA]; terutroban inhibits the reaction [Streptozocin results in increased expression of NOS2 protein]
Streptozocin results in increased expression of NOS2 mRNA; Streptozocin results in increased expression of NOS2 protein
1-hexacosanol inhibits the reaction [Streptozocin results in increased expression of NOS2 mRNA]; 1-hexacosanol inhibits the reaction [Streptozocin results in increased expression of NOS2 protein]; [Ascorbic Acid co-treated with Vitamin E co-treated with beta Carotene co-treated with Copper] inhibits the reaction [Streptozocin results in increased expression of NOS2 mRNA]; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of NOS2 mRNA; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of NOS2 mRNA]; candesartan inhibits the reaction [Streptozocin results in increased expression of NOS2 protein]; cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in increased expression of NOS2 protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of NOS2 protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased activity of NOS2 protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of NOS2 mRNA]; Kangen-karyu inhibits the reaction [Streptozocin results in increased expression of NOS2 protein]; Metformin inhibits the reaction [Streptozocin results in increased activity of NOS2 protein]; Metoprolol inhibits the reaction [Streptozocin results in increased expression of NOS2 protein]; Plant Extracts inhibits the reaction [Streptozocin results in increased expression of NOS2 mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of NOS2 protein]; tin mesoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in increased expression of NOS2 protein]]; Triterpenes inhibits the reaction [Streptozocin results in increased activity of NOS2 protein]; Triterpenes inhibits the reaction [Streptozocin results in increased expression of NOS2 mRNA]
CTD PMID:15821039 PMID:16139267 PMID:16177186 PMID:16309587 PMID:16380483 More... NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell multiple interactions
increases expression
decreases phosphorylation
decreases expression
ISO 1,3-dimethoxy-5-methyl-2-(3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl)benzene inhibits the reaction [4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in decreased phosphorylation of NOS3 protein]]; 1-hexacosanol inhibits the reaction [Streptozocin results in decreased expression of NOS3 protein]; 4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in decreased phosphorylation of NOS3 protein]; [Sildenafil Citrate co-treated with Resveratrol] inhibits the reaction [Streptozocin results in decreased expression of NOS3 protein]; [Streptozocin co-treated with Dietary Fats] results in decreased expression of NOS3 mRNA; Acetylcysteine inhibits the reaction [Streptozocin results in decreased phosphorylation of NOS3 protein]; Allopurinol inhibits the reaction [Streptozocin results in decreased phosphorylation of NOS3 protein]; Allopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased phosphorylation of NOS3 protein]]; Atorvastatin inhibits the reaction [Streptozocin results in decreased expression of NOS3 protein]; candesartan inhibits the reaction [Streptozocin results in increased expression of NOS3 mRNA]; candesartan inhibits the reaction [Streptozocin results in increased expression of NOS3 protein]; Cholesterol, Dietary inhibits the reaction [Streptozocin results in increased expression of NOS3 protein]; cloricromen inhibits the reaction [Streptozocin results in increased expression of NOS3 protein]; cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased phosphorylation of NOS3 protein]; esculetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NOS3 mRNA]; Resveratrol inhibits the reaction [Streptozocin promotes the reaction [CAV1 protein binds to NOS3 protein]]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of NOS3 mRNA]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of NOS3 protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased phosphorylation of NOS3 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of NOS3 mRNA]; Streptozocin promotes the reaction [CAV1 protein binds to NOS3 protein]; Streptozocin results in decreased activity of and results in decreased phosphorylation of NOS3 protein
Streptozocin results in increased expression of NOS3 mRNA; Streptozocin results in increased expression of NOS3 protein
Streptozocin results in decreased expression of NOS3 mRNA; Streptozocin results in decreased expression of NOS3 protein
CTD PMID:11696579 PMID:12377873 PMID:14871415 PMID:16045816 PMID:16139267 More... NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472
JBrowse link
G Nox4 NADPH oxidase 4 multiple interactions
increases expression
ISO
EXP
[Resveratrol co-treated with Streptozocin] results in decreased expression of NOX4 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of NOX4 protein; Bezafibrate inhibits the reaction [Streptozocin results in increased expression of NOX4 mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NOX4 protein]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of NOX4 mRNA]
[Streptozocin co-treated with Dietary Fats] results in decreased expression of NOX4 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of NOX4 protein; aucubin inhibits the reaction [Streptozocin results in increased expression of NOX4 protein]
CTD PMID:16979161 PMID:25905778 PMID:29127188 PMID:35085591 PMID:35961541 NCBI chr 7:86,893,638...87,047,918
Ensembl chr 7:86,895,304...87,047,918
JBrowse link
G Npas2 neuronal PAS domain protein 2 decreases expression ISO Streptozocin results in decreased expression of NPAS2 mRNA CTD PMID:25905778 NCBI chr 1:39,233,013...39,402,321
Ensembl chr 1:39,232,812...39,402,317
JBrowse link
G Nphs1 nephrosis 1, nephrin decreases expression ISO
EXP
Streptozotocin decreases expression of Nphs1 mRNA and protein in kidney
Streptozotocin decreases expression of Nphs1 mRNA and protein in renal glomerulus
Streptozocin decreases expression of Nphs1 mRNA in kidney
streptozotocin decreases expression of Nphs1 protein in kidney
RGD PMID:17624267 PMID:30862474 PMID:24173355 PMID:21617141 RGD:38596322, RGD:38596325, RGD:38599008, RGD:7241083 NCBI chr 7:30,157,259...30,188,048
Ensembl chr 7:30,157,740...30,186,648
JBrowse link
G Nphs2 nephrosis 2, podocin multiple interactions
decreases expression
ISO
EXP
Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in decreased expression of NPHS2 mRNA]; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in decreased expression of NPHS2 protein]; procyanidin B2 inhibits the reaction [Streptozocin results in increased expression of NPHS2 mRNA]; procyanidin B2 inhibits the reaction [Streptozocin results in increased expression of NPHS2 protein]
Streptozocin results in decreased expression of NPHS2 mRNA; Streptozocin results in decreased expression of NPHS2 protein
AM6545 inhibits the reaction [Streptozocin results in decreased expression of NPHS2 mRNA]; AM6545 inhibits the reaction [Streptozocin results in decreased expression of NPHS2 protein]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in decreased expression of NPHS2 mRNA]]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in decreased expression of NPHS2 protein]]; Perindopril inhibits the reaction [Streptozocin results in decreased expression of NPHS2 mRNA]; Perindopril inhibits the reaction [Streptozocin results in decreased expression of NPHS2 protein]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in decreased expression of NPHS2 mRNA]]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in decreased expression of NPHS2 protein]]
CTD PMID:20547220 PMID:25199697 PMID:30184259 NCBI chr 1:156,138,105...156,155,605
Ensembl chr 1:156,138,297...156,155,605
JBrowse link
G Nppa natriuretic peptide type A increases expression
multiple interactions
ISO
EXP
Streptozocin results in increased expression of NPPA mRNA; Streptozocin results in increased expression of NPPA protein
SLC25A4 protein inhibits the reaction [Streptozocin results in increased expression of NPPA mRNA]
Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in increased expression of NPPA protein]
CTD PMID:16409969 PMID:16980342 PMID:18945756 NCBI chr 4:148,085,179...148,086,531
Ensembl chr 4:148,085,179...148,086,536
JBrowse link
G Nppb natriuretic peptide type B increases expression
multiple interactions
ISO
EXP
Streptozocin results in increased expression of NPPB mRNA
[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of NPPB protein; Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of NPPB protein]
[Streptozocin co-treated with Dietary Fats] results in increased expression of NPPB protein; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NPPB protein]
CTD PMID:10828832 PMID:34610774 PMID:34801538 NCBI chr 4:148,070,264...148,071,662
Ensembl chr 4:148,070,245...148,071,662
JBrowse link
G Nppc natriuretic peptide type C decreases expression ISO Streptozocin results in decreased expression of NPPC mRNA CTD PMID:10828832 NCBI chr 1:86,594,015...86,598,295
Ensembl chr 1:86,594,013...86,598,293
JBrowse link
G Npy neuropeptide Y multiple interactions
increases expression
ISO INS protein inhibits the reaction [Streptozocin results in increased expression of NPY mRNA] CTD PMID:20219977 NCBI chr 6:49,799,690...49,806,487
Ensembl chr 6:49,799,690...49,806,487
JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 multiple interactions
decreases expression
affects response to substance
increases expression
ISO
EXP
diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of NQO1 mRNA]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of NQO1 protein]; Metformin inhibits the reaction [Streptozocin results in decreased expression of NQO1 mRNA]; Metformin inhibits the reaction [Streptozocin results in decreased expression of NQO1 protein]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of NQO1 mRNA]
Streptozocin results in decreased expression of NQO1 mRNA; Streptozocin results in decreased expression of NQO1 protein
NQO1 protein affects the susceptibility to Streptozocin
Streptozocin results in increased expression of NQO1 mRNA
2,5-dihydroxybenzoic acid promotes the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of NQO1 mRNA]; [omaveloxolone analog co-treated with Streptozocin co-treated with Dietary Fats] results in increased activity of NQO1 protein; [omaveloxolone co-treated with Streptozocin co-treated with Dietary Fats] results in increased activity of NQO1 protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of NQO1 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of NQO1 mRNA; [Streptozocin co-treated with Niacinamide] results in increased expression of NQO1 mRNA; [Streptozocin co-treated with NQO1 protein mutant form] results in increased expression of AIFM1 protein; [Streptozocin co-treated with NQO1 protein mutant form] results in increased expression of CASP3 protein modified form; [Streptozocin co-treated with NQO1 protein mutant form] results in increased secretion of DIABLO protein; [Streptozocin co-treated with sulforaphane] results in increased expression of NQO1; Metformin promotes the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of NQO1 mRNA]; omaveloxolone analog promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NQO1 mRNA]; omaveloxolone promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NQO1 mRNA]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NQO1 mRNA]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of NQO1 mRNA]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of NQO1 protein]
CTD PMID:21457706 PMID:22023613 PMID:22531820 PMID:23319174 PMID:23458895 More... NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 multiple interactions ISO
EXP
[resveratrol co-treated with Streptozocin] results in increased expression of NR0B2 mRNA
[Dietary Fats co-treated with Streptozocin] results in increased expression of NR0B2 protein
CTD PMID:25905778 PMID:29382564 NCBI chr 4:133,280,687...133,283,997
Ensembl chr 4:133,280,687...133,283,847
JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 decreases expression ISO Streptozocin results in decreased expression of NR1D1 mRNA CTD PMID:25905778 NCBI chr11:98,658,758...98,666,233
Ensembl chr11:98,658,758...98,666,159
JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 decreases expression
multiple interactions
ISO Streptozocin results in decreased expression of NR1H2 protein
[homocastasterone analog co-treated with Streptozocin] results in increased expression of NR1H2 mRNA; homocastasterone analog inhibits the reaction [Streptozocin results in decreased expression of NR1H2 protein]
CTD PMID:28822685 NCBI chr 7:44,199,040...44,204,928
Ensembl chr 7:44,199,040...44,203,375
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 multiple interactions
increases expression
ISO [homocastasterone analog co-treated with Streptozocin] results in increased expression of NR1H3 mRNA; [homocastasterone analog co-treated with Streptozocin] results in increased expression of NR1H3 protein; Allopurinol inhibits the reaction [Streptozocin results in increased expression of NR1H3 mRNA]; Allopurinol inhibits the reaction [Streptozocin results in increased expression of NR1H3 protein]; Quercetin inhibits the reaction [Streptozocin results in increased expression of NR1H3 mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of NR1H3 protein]
Streptozocin results in increased expression of NR1H3 mRNA; Streptozocin results in increased expression of NR1H3 protein
CTD PMID:23647015 PMID:28822685 NCBI chr 2:91,014,406...91,033,189
Ensembl chr 2:91,014,406...91,033,179
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions EXP [Dietary Fats co-treated with Streptozocin] results in decreased expression of NR1H4 protein CTD PMID:29382564 NCBI chr10:89,290,096...89,369,484
Ensembl chr10:89,290,096...89,369,447
JBrowse link
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 decreases expression
multiple interactions
ISO Streptozocin results in decreased expression of NR5A1 mRNA; Streptozocin results in decreased expression of NR5A1 protein
carvacrol affects the reaction [Streptozocin results in decreased expression of NR5A1 mRNA]; carvacrol affects the reaction [Streptozocin results in decreased expression of NR5A1 protein]
CTD PMID:32153207 NCBI chr 2:38,582,668...38,604,554
Ensembl chr 2:38,582,668...38,604,554
JBrowse link
G Nt5e 5' nucleotidase, ecto multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of NT5E mRNA CTD PMID:29127188 NCBI chr 9:88,209,662...88,254,142
Ensembl chr 9:88,209,250...88,254,145
JBrowse link
G Ntf3 neurotrophin 3 affects localization ISO Streptozocin affects the localization of NTF3 protein CTD PMID:12031555 NCBI chr 6:126,078,375...126,143,703
Ensembl chr 6:126,078,375...126,143,873
JBrowse link
G Ntn1 netrin 1 decreases expression
multiple interactions
EXP Streptozocin results in decreased expression of NTN1 protein
[NTN1 protein co-treated with Streptozocin] results in increased expression of ARG1 protein; NTN1 protein inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; NTN1 protein inhibits the reaction [Streptozocin results in increased expression of CDKN2A mRNA]; NTN1 protein inhibits the reaction [Streptozocin results in increased expression of CDKN2A protein]; NTN1 protein inhibits the reaction [Streptozocin results in increased expression of PTGS2 protein]; NTN1 protein inhibits the reaction [Streptozocin results in increased expression of RELA protein]; NTN1 protein inhibits the reaction [Streptozocin results in increased expression of TRP53 mRNA]; NTN1 protein promotes the reaction [Streptozocin results in increased expression of DCC mRNA]; NTN1 protein promotes the reaction [Streptozocin results in increased expression of DCC protein]; Streptozocin promotes the reaction [NTN1 protein results in increased phosphorylation of MAPK1 protein]; Streptozocin promotes the reaction [NTN1 protein results in increased phosphorylation of MAPK3 protein]
CTD PMID:29059224 NCBI chr11:68,100,190...68,277,652
Ensembl chr11:68,100,190...68,291,649
JBrowse link
G Ntrk1 neurotrophic tyrosine kinase, receptor, type 1 multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of NTRK1 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of NTRK1 mRNA; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NTRK1 mRNA] CTD PMID:33484791 NCBI chr 3:87,685,551...87,702,549
Ensembl chr 3:87,685,551...87,702,469
JBrowse link
G Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 multiple interactions
decreases phosphorylation
decreases expression
EXP
ISO
Acetylcysteine inhibits the reaction [Streptozocin results in decreased phosphorylation of NTRK2 protein]; Physostigmine inhibits the reaction [Streptozocin results in decreased phosphorylation of NTRK2 protein]
Metformin inhibits the reaction [Streptozocin results in increased expression of NTRK2 mRNA]; morin inhibits the reaction [Streptozocin results in increased expression of NTRK2 mRNA]
Streptozocin results in decreased expression of NTRK2 mRNA
CTD PMID:28499986 PMID:35414346 NCBI chr13:58,954,363...59,281,782
Ensembl chr13:58,954,383...59,281,784
JBrowse link
G Nudt7 nudix hydrolase 7 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of NUDT7 mRNA CTD PMID:29127188 NCBI chr 8:114,860,314...114,881,471
Ensembl chr 8:114,860,297...114,881,479
JBrowse link
G Nus1 NUS1 dehydrodolichyl diphosphate synthase subunit multiple interactions EXP [Dietary Fats co-treated with Streptozocin] results in decreased expression of NUS1 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of NUS1 protein; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of MFN2 mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PPARGC1A mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SIRT1 mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of GSK3B protein]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of ACACA mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of ATF4 mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of ATF6 mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of DGAT1 mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of EIF2AK3 protein]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FASN mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GK mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of HSPA5 mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of HSPA5 protein]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of INPP5K mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SREBF1 mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased phosphorylation of EIF2S1 protein]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased splicing of XBP1 mRNA] CTD PMID:33812996 NCBI chr10:52,293,643...52,316,288
Ensembl chr10:52,293,643...52,316,279
JBrowse link
G Nyap1 neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1 multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of NYAP1 mRNA CTD PMID:33484791 NCBI chr 5:137,729,144...137,739,430
Ensembl chr 5:137,728,161...137,739,869
JBrowse link
G Oat ornithine aminotransferase decreases expression
multiple interactions
ISO Streptozocin results in decreased expression of OAT protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of OAT protein]
CTD PMID:19634143 NCBI chr 7:132,159,204...132,178,127
Ensembl chr 7:132,159,207...132,178,127
JBrowse link
G Ocln occludin decreases expression
multiple interactions
EXP Streptozocin results in decreased expression of OCLN protein
rhodioloside inhibits the reaction [Streptozocin results in decreased expression of OCLN protein]
CTD PMID:31682803 NCBI chr13:100,633,012...100,689,226
Ensembl chr13:100,633,015...100,689,226
JBrowse link
G Oga O-GlcNAcase multiple interactions ISO Streptozocin binds to and results in decreased activity of OGA protein
[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of OGA protein; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of OGA protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of OGA protein]
CTD PMID:18721751 PMID:30551545 NCBI chr19:45,738,698...45,772,274
Ensembl chr19:45,738,698...45,772,276
JBrowse link
G Ogdh oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) multiple interactions
increases expression
ISO Trientine inhibits the reaction [Streptozocin results in increased expression of OGDH protein] CTD PMID:19634143 NCBI chr11:6,241,597...6,309,094
Ensembl chr11:6,241,633...6,306,642
JBrowse link
G Opn4 opsin 4 (melanopsin) multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of OPN4 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of OPN4 mRNA] CTD PMID:33484791 NCBI chr14:34,312,575...34,322,099
Ensembl chr14:34,312,575...34,322,099
JBrowse link
G Or51e2 olfactory receptor family 51 subfamily E member 2 decreases expression ISO Streptozocin results in decreased expression of OLR59 mRNA CTD PMID:25905778 NCBI chr 7:102,389,928...102,408,678
Ensembl chr 7:102,387,718...102,408,678
JBrowse link
G Orm1 orosomucoid 1 multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of ORM1 mRNA CTD PMID:25905778 NCBI chr 4:63,262,793...63,266,400
Ensembl chr 4:63,262,797...63,266,400
JBrowse link
G Orm2 orosomucoid 2 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of ORM2 mRNA; Diethylhexyl Phthalate affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of ORM2 mRNA]; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of ORM2 mRNA] CTD PMID:33484791 NCBI chr 4:63,280,543...63,284,114
Ensembl chr 4:63,280,686...63,284,115
JBrowse link
G P2rx2 purinergic receptor P2X, ligand-gated ion channel, 2 increases expression EXP Streptozocin results in increased expression of P2RX2 mRNA CTD PMID:19383439 NCBI chr 5:110,487,678...110,491,186
Ensembl chr 5:110,487,678...110,491,078
JBrowse link
G P2rx3 purinergic receptor P2X, ligand-gated ion channel, 3 increases expression EXP Streptozocin results in increased expression of P2RX3 mRNA CTD PMID:19383439 NCBI chr 2:84,826,893...84,867,446
Ensembl chr 2:84,828,927...84,867,806
JBrowse link
G Pabpc1l poly(A) binding protein, cytoplasmic 1-like multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of PABPC1L mRNA CTD PMID:33484791 NCBI chr 2:163,866,685...163,892,458
Ensembl chr 2:163,867,370...163,892,458
JBrowse link
G Pah phenylalanine hydroxylase multiple interactions
increases activity
increases expression
ISO peroxovanadate inhibits the reaction [Streptozocin results in increased activity of PAH protein]; peroxovanadate inhibits the reaction [Streptozocin results in increased expression of PAH mRNA] CTD PMID:11055810 NCBI chr10:87,357,657...87,419,999
Ensembl chr10:87,357,657...87,419,998
JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of PAK1 mRNA CTD PMID:29127188 NCBI chr 7:97,437,748...97,561,588
Ensembl chr 7:97,437,748...97,561,588
JBrowse link
G Parg poly (ADP-ribose) glycohydrolase increases response to substance EXP PARG gene mutant form results in increased susceptibility to Streptozocin CTD PMID:15282315 NCBI chr14:31,923,900...32,020,671
Ensembl chr14:31,923,906...32,019,507
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 increases cleavage
multiple interactions
increases activity
ISO
EXP
Streptozocin results in increased cleavage of PARP1 protein
Anthocyanins inhibits the reaction [Streptozocin results in increased cleavage of PARP1 protein]; Curcumin inhibits the reaction [Streptozocin results in increased cleavage of PARP1 protein]
Streptozocin results in increased activity of PARP1 protein
[Streptozocin co-treated with Dietary Fats] results in increased expression of PARP1 mRNA; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Streptozocin results in increased activity of PARP1 protein]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of PARP1 mRNA]; SIRT1 protein inhibits the reaction [Streptozocin promotes the reaction [JUN protein binds to PARP1 protein]]; SIRT1 protein inhibits the reaction [Streptozocin promotes the reaction [PARP1 protein binds to MMP9 promoter]]; SIRT1 protein inhibits the reaction [Streptozocin promotes the reaction [RELA protein binds to PARP1 protein]]; Streptozocin promotes the reaction [JUN protein binds to PARP1 protein]; Streptozocin promotes the reaction [PARP1 protein binds to MMP9 promoter]; Streptozocin promotes the reaction [RELA protein binds to PARP1 protein]
CTD PMID:25541178 PMID:27288104 PMID:28478229 PMID:28856781 PMID:34610774 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
JBrowse link
G Pax8 paired box 8 multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of PAX8 mRNA; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of PAX8 mRNA] CTD PMID:32303808 NCBI chr 2:24,310,563...24,365,611
Ensembl chr 2:24,310,572...24,365,611
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1, cytosolic multiple interactions
increases expression
ISO
EXP
bis(maltolato)oxovanadium(IV) inhibits the reaction [Streptozocin results in increased expression of PCK1 mRNA]; cinnamaldehyde inhibits the reaction [Streptozocin results in increased expression of PCK1 mRNA]; Glyburide inhibits the reaction [Streptozocin results in increased expression of PCK1 mRNA]; Trientine inhibits the reaction [Streptozocin results in increased expression of PCK1 protein]
Streptozocin results in increased expression of PCK1 mRNA; Streptozocin results in increased expression of PCK1 protein
[1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of PCK1 protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of PCK1 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of PCK1 mRNA; Acrylamide inhibits the reaction [Streptozocin results in increased expression of PCK1 mRNA]; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of PCK1 mRNA]
CTD PMID:12446591 PMID:19634143 PMID:20363216 PMID:25446853 PMID:26522834 More... NCBI chr 2:172,994,866...173,001,067
Ensembl chr 2:172,994,841...173,001,066
JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) increases expression
multiple interactions
ISO
EXP
Streptozocin results in increased expression of PCK2 protein
Tribulus extract inhibits the reaction [Streptozocin results in increased expression of PCK2 protein]
[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of PCK2 protein; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of PCK2 protein]
CTD PMID:36627075 PMID:39047806 NCBI chr14:55,777,721...55,787,477
Ensembl chr14:55,777,723...55,788,699
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO
EXP
[Streptozocin co-treated with Tobacco Smoke Pollution] results in increased expression of PCNA protein
[Streptozocin co-treated with Dextran Sulfate] results in increased expression of PCNA protein
CTD PMID:30421503 PMID:34964214 NCBI chr 2:132,091,206...132,095,100
Ensembl chr 2:132,091,082...132,095,234
JBrowse link
G Pcsk1 proprotein convertase subtilisin/kexin type 1 multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of PCSK1 mRNA CTD PMID:25905778 NCBI chr13:75,237,407...75,282,980
Ensembl chr13:75,237,945...75,282,980
JBrowse link
G Pcx pyruvate carboxylase increases expression
multiple interactions
ISO
EXP
Streptozocin results in increased expression of PC protein
Trientine inhibits the reaction [Streptozocin results in increased expression of PC protein]
[1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of PCX protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of PCX protein
CTD PMID:19634143 PMID:25446853 NCBI chr19:4,560,500...4,671,780
Ensembl chr19:4,560,500...4,671,780
JBrowse link
G Pde4b phosphodiesterase 4B, cAMP specific decreases expression ISO Streptozocin results in decreased expression of PDE4B mRNA CTD PMID:25905778 NCBI chr 4:101,944,529...102,464,459
Ensembl chr 4:101,944,740...102,464,456
JBrowse link
G Pde5a phosphodiesterase 5A, cGMP-specific multiple interactions
increases expression
ISO [Sildenafil Citrate co-treated with Resveratrol] inhibits the reaction [Streptozocin results in increased expression of PDE5A protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of PDE5A protein]
Streptozocin results in increased expression of PDE5A mRNA; Streptozocin results in increased expression of PDE5A protein
CTD PMID:26006044 NCBI chr 3:122,522,822...122,653,023
Ensembl chr 3:122,522,596...122,653,023
JBrowse link
G Pde6c phosphodiesterase 6C, cGMP specific, cone, alpha prime multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of PDE6C mRNA CTD PMID:33484791 NCBI chr19:38,121,220...38,172,391
Ensembl chr19:38,121,229...38,172,406
JBrowse link
G Pdgfra platelet derived growth factor receptor, alpha polypeptide decreases expression EXP Streptozocin results in decreased expression of PDGFRA mRNA CTD PMID:26073000 NCBI chr 5:75,311,988...75,358,867
Ensembl chr 5:75,312,953...75,358,876
JBrowse link
G Pdgfrl platelet-derived growth factor receptor-like multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of PDGFRL mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PDGFRL mRNA] CTD PMID:33484791 NCBI chr 8:41,379,270...41,443,819
Ensembl chr 8:41,379,249...41,443,822
JBrowse link
G Pdk1 pyruvate dehydrogenase kinase, isoenzyme 1 multiple interactions EXP [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of PDK1 mRNA]; [Dietary Fats co-treated with Streptozocin] results in increased expression of PDK1 mRNA CTD PMID:25446853 NCBI chr 2:71,703,398...71,734,202
Ensembl chr 2:71,703,568...71,734,202
JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 decreases expression
multiple interactions
EXP Streptozocin results in decreased expression of PDX1 mRNA
[Dietary Fats co-treated with Streptozocin] results in decreased expression of PDX1 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of PDX1 protein; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PDX1 mRNA]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PDX1 protein]; octylphenol inhibits the reaction [Streptozocin results in decreased expression of PDX1 mRNA]
CTD PMID:24781736 PMID:29935216 PMID:33359794 NCBI chr 5:147,206,907...147,212,658
Ensembl chr 5:147,206,769...147,212,658
JBrowse link
G Pdxp pyridoxal (pyridoxine, vitamin B6) phosphatase multiple interactions
increases expression
ISO [resveratrol co-treated with Streptozocin] results in decreased expression of PDXP mRNA
Streptozocin results in increased expression of PDXP mRNA
CTD PMID:25905778 NCBI chr15:78,796,342...78,803,717
Ensembl chr15:78,798,119...78,803,717
JBrowse link
G Pecam1 platelet/endothelial cell adhesion molecule 1 multiple interactions EXP [Dietary Fats co-treated with Streptozocin] results in increased expression of PECAM1 protein; Rosuvastatin Calcium inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of PECAM1 protein]; sarpogrelate inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of PECAM1 protein] CTD PMID:27097221 NCBI chr11:106,545,039...106,606,107
Ensembl chr11:106,545,043...106,641,454
JBrowse link
G Pemt phosphatidylethanolamine N-methyltransferase increases activity
affects expression
ISO
EXP
Streptozocin results in increased activity of PEMT protein
Streptozocin affects the expression of PEMT mRNA
CTD PMID:16835399 PMID:18583417 NCBI chr11:59,861,440...59,937,394
Ensembl chr11:59,861,440...59,937,315
JBrowse link
G Pfkfb1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 increases expression ISO Streptozocin results in increased expression of PFKFB1 mRNA CTD PMID:25905778 NCBI chr  X:149,370,441...149,426,874
Ensembl chr  X:149,371,225...149,426,874
JBrowse link
G Pfkfb2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 decreases activity
multiple interactions
ISO Streptozocin results in decreased activity of PFKFB2 protein
Lithium Carbonate inhibits the reaction [Streptozocin results in decreased activity of PFKFB2 protein]
CTD PMID:10700396 NCBI chr 1:130,616,780...130,656,990
Ensembl chr 1:130,616,919...130,656,990
Ensembl chr 1:130,616,919...130,656,990
JBrowse link
G Pfkp phosphofructokinase, platelet multiple interactions EXP [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PFKP protein]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of PFKP protein CTD PMID:25446853 NCBI chr13:6,629,910...6,699,096
Ensembl chr13:6,629,804...6,698,813
JBrowse link
G Phactr3 phosphatase and actin regulator 3 multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of PHACTR3 mRNA CTD PMID:33484791 NCBI chr 2:177,760,768...177,980,285
Ensembl chr 2:177,760,768...177,980,285
JBrowse link
G Phb1 prohibitin 1 decreases expression ISO Streptozocin results in decreased expression of PHB1 protein CTD PMID:21136691 NCBI chr11:95,557,783...95,571,599
Ensembl chr11:95,557,783...95,571,599
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha multiple interactions EXP streptozocin decreases expression and increases phosphorylation of Pik3ca in cardiac muscle cells RGD PMID:36044268 RGD:156430337 NCBI chr 3:32,451,203...32,520,256
Ensembl chr 3:32,451,820...32,522,635
JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta decreases expression
multiple interactions
ISO
EXP
Streptozocin results in decreased expression of PIK3CB mRNA
resveratrol inhibits the reaction [Streptozocin results in decreased expression of PIK3CB mRNA]
[Streptozocin co-treated with Dietary Fats] results in decreased expression of PIK3CB protein; Dibutyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PIK3CB protein]; L 783281 inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PIK3CB protein]; L 783281 inhibits the reaction [Dibutyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PIK3CB protein]]
CTD PMID:26071184 PMID:29526571 NCBI chr 9:98,920,455...99,022,264
Ensembl chr 9:98,918,707...99,022,674
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 decreases expression
multiple interactions
ISO
EXP
Streptozocin results in decreased expression of PIK3R1 mRNA
Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of PIK3R1 mRNA]; Rivastigmine inhibits the reaction [Streptozocin results in decreased expression of PIK3R1 mRNA]; Wortmannin inhibits the reaction [Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of PIK3R1 mRNA]]
[Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of PIK3R1 protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of PIK3R1 protein]
CTD PMID:32805344 PMID:33484791 NCBI chr13:101,817,269...101,904,725
Ensembl chr13:101,817,071...101,904,725
JBrowse link
G Pink1 PTEN induced putative kinase 1 multiple interactions EXP [Dietary Fats co-treated with Streptozocin] results in increased expression of PINK1 mRNA CTD PMID:33812996 NCBI chr 4:138,040,718...138,053,631
Ensembl chr 4:138,040,720...138,053,618
JBrowse link
G Pitpnc1 phosphatidylinositol transfer protein, cytoplasmic 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of PITPNC1 mRNA CTD PMID:20665664 NCBI chr11:107,098,718...107,361,546
Ensembl chr11:107,098,718...107,361,525
JBrowse link
G Pklr pyruvate kinase liver and red blood cell multiple interactions
decreases expression
ISO
EXP
cinnamaldehyde inhibits the reaction [Streptozocin results in decreased expression of PKLR mRNA]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of PKLR mRNA]
[1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PKLR protein]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of PKLR protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of PKLR mRNA; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PKLR mRNA]
CTD PMID:20363216 PMID:25446853 PMID:26522834 NCBI chr 3:89,043,429...89,054,122
Ensembl chr 3:89,043,449...89,054,091
JBrowse link
G Pkm pyruvate kinase, muscle affects expression EXP Streptozocin affects the expression of PKM mRNA CTD PMID:18583417 NCBI chr 9:59,563,859...59,586,655
Ensembl chr 9:59,563,651...59,586,658
JBrowse link
G Pla2g7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of PLA2G7 mRNA CTD PMID:29127188 NCBI chr17:43,879,009...43,923,093
Ensembl chr17:43,878,989...43,923,092
JBrowse link
G Plaat3 phospholipase A and acyltransferase 3 multiple interactions ISO [Resveratrol co-treated with Streptozocin] results in increased expression of PLAAT3 mRNA CTD PMID:25905778 NCBI chr19:7,534,824...7,565,914
Ensembl chr19:7,534,824...7,565,910
JBrowse link
G Plau plasminogen activator, urokinase increases expression
multiple interactions
ISO Streptozocin results in increased expression of PLAU mRNA; Streptozocin results in increased expression of PLAU protein
[resveratrol co-treated with Streptozocin] results in increased expression of PLAU mRNA; benazepril inhibits the reaction [Streptozocin results in increased expression of PLAU mRNA]
CTD PMID:15322501 PMID:25905778 NCBI chr14:20,886,730...20,893,456
Ensembl chr14:20,886,728...20,893,453
JBrowse link
G Plaur plasminogen activator, urokinase receptor increases expression
multiple interactions
ISO
EXP
Streptozocin results in increased expression of PLAUR mRNA; Streptozocin results in increased expression of PLAUR protein
benazepril inhibits the reaction [Streptozocin results in increased expression of PLAUR mRNA]
[Streptozocin co-treated with Dietary Fats] results in increased expression of PLAUR mRNA
CTD PMID:15322501 PMID:29127188 NCBI chr 7:24,161,857...24,175,393
Ensembl chr 7:24,161,909...24,175,393
JBrowse link
G Plcb1 phospholipase C, beta 1 multiple interactions
increases expression
ISO acetovanillone inhibits the reaction [Streptozocin results in increased expression of PLCB1 protein]; CAT protein inhibits the reaction [Streptozocin results in increased expression of PLCB1 protein] CTD PMID:20691780 NCBI chr 2:134,628,084...135,317,178
Ensembl chr 2:134,627,987...135,317,178
JBrowse link
G Plcb2 phospholipase C, beta 2 multiple interactions
increases expression
ISO acetovanillone inhibits the reaction [Streptozocin results in increased expression of PLCB2 protein]; CAT protein inhibits the reaction [Streptozocin results in increased expression of PLCB2 protein] CTD PMID:20691780 NCBI chr 2:118,535,484...118,559,140
Ensembl chr 2:118,537,998...118,558,919
JBrowse link
G Plch1 phospholipase C, eta 1 multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of PLCH1 mRNA CTD PMID:33484791 NCBI chr 3:63,603,620...63,806,929
Ensembl chr 3:63,603,655...63,806,893
JBrowse link
G Plin2 perilipin 2 multiple interactions ISO [resveratrol co-treated with Streptozocin] results in decreased expression of PLIN2 mRNA CTD PMID:25905778 NCBI chr 4:86,545,147...86,588,518
Ensembl chr 4:86,566,623...86,588,297
JBrowse link
G Pln phospholamban decreases expression
multiple interactions
ISO Streptozocin results in decreased expression of PLN mRNA; Streptozocin results in decreased expression of PLN protein
Triterpenes inhibits the reaction [Streptozocin results in decreased expression of PLN mRNA]; Triterpenes inhibits the reaction [Streptozocin results in decreased expression of PLN protein]
CTD PMID:19000375 NCBI chr10:53,213,782...53,222,095
Ensembl chr10:53,213,763...53,222,083
JBrowse link
G Plscr1 phospholipid scramblase 1 multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of PLSCR1 mRNA CTD PMID:25905778 NCBI chr 9:92,132,265...92,154,034
Ensembl chr 9:92,131,803...92,154,331
JBrowse link
G Pmp22 peripheral myelin protein 22 multiple interactions
decreases expression
ISO Progesterone inhibits the reaction [Streptozocin results in decreased expression of PMP22 mRNA] CTD PMID:17187935 NCBI chr11:63,019,808...63,050,373
Ensembl chr11:63,019,808...63,050,373
JBrowse link
G Pnpla2 patatin-like phospholipase domain containing 2 multiple interactions EXP [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of PNPLA2 protein; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of PNPLA2 protein] CTD PMID:39047806 NCBI chr 7:141,035,101...141,040,656
Ensembl chr 7:141,035,111...141,040,656
JBrowse link
G Pnpt1 polyribonucleotide nucleotidyltransferase 1 affects expression EXP Streptozocin affects the expression of PNPT1 mRNA CTD PMID:18583417 NCBI chr11:29,080,236...29,112,010
Ensembl chr11:29,080,744...29,111,828
JBrowse link
G Polg polymerase (DNA directed), gamma affects expression EXP Streptozocin affects the expression of POLG mRNA CTD PMID:18583417 NCBI chr 7:79,095,979...79,117,659
Ensembl chr 7:79,095,979...79,116,110
JBrowse link
G Polg2 polymerase (DNA directed), gamma 2, accessory subunit affects expression EXP Streptozocin affects the expression of POLG2 mRNA CTD PMID:18583417 NCBI chr11:106,659,030...106,670,363
Ensembl chr11:106,659,079...106,670,363
JBrowse link
G Pomc pro-opiomelanocortin-alpha multiple interactions
decreases expression
ISO INS protein inhibits the reaction [Streptozocin results in decreased expression of POMC mRNA] CTD PMID:20219977 NCBI chr12:4,004,945...4,010,643
Ensembl chr12:4,004,951...4,010,642
JBrowse link
G Pon1 paraoxonase 1 multiple interactions
decreases expression
decreases activity
ISO [Propolis co-treated with Chlorpyrifos co-treated with Streptozocin] results in decreased expression of PON1 mRNA; [Propolis co-treated with Chlorpyrifos co-treated with Streptozocin] results in decreased expression of PON1 protein; [Propolis co-treated with Streptozocin] results in decreased expression of PON1 protein; [Streptozocin co-treated with Chlorpyrifos] inhibits the reaction [Propolis results in increased expression of PON1 mRNA]; [Streptozocin co-treated with Chlorpyrifos] inhibits the reaction [Propolis results in increased expression of PON1 protein]; [Streptozocin co-treated with Chlorpyrifos] results in decreased expression of PON1 mRNA; [Streptozocin co-treated with Chlorpyrifos] results in decreased expression of PON1 protein; Chlorpyrifos inhibits the reaction [Streptozocin results in decreased expression of PON1 protein]; Chlorpyrifos promotes the reaction [Streptozocin results in decreased expression of PON1 mRNA]; Propolis inhibits the reaction [[Streptozocin co-treated with Chlorpyrifos] results in decreased expression of PON1 mRNA]; Propolis inhibits the reaction [[Streptozocin co-treated with Chlorpyrifos] results in decreased expression of PON1 protein]; Propolis inhibits the reaction [Streptozocin results in decreased expression of PON1 mRNA]; Propolis inhibits the reaction [Streptozocin results in decreased expression of PON1 protein]; Streptozocin inhibits the reaction [Chlorpyrifos results in decreased expression of PON1 protein]; Streptozocin inhibits the reaction [Propolis results in increased expression of PON1 mRNA]; Streptozocin inhibits the reaction [Propolis results in increased expression of PON1 protein]; Streptozocin promotes the reaction [Chlorpyrifos results in decreased expression of PON1 mRNA]
Streptozocin results in decreased expression of PON1 mRNA; Streptozocin results in decreased expression of PON1 protein
Streptozocin results in decreased activity of PON1 protein
CTD PMID:31400774 PMID:34039237 NCBI chr 6:5,168,101...5,193,824
Ensembl chr 6:5,168,090...5,193,946
JBrowse link
G Por cytochrome p450 oxidoreductase increases expression ISO Streptozocin results in increased expression of POR mRNA CTD PMID:25905778 NCBI chr 5:135,698,894...135,764,180
Ensembl chr 5:135,698,887...135,764,180
JBrowse link
G Pou1f1 POU domain, class 1, transcription factor 1 increases expression
multiple interactions
EXP Streptozocin results in increased expression of POU1F1 mRNA; Streptozocin results in increased expression of POU1F1 protein
INS1 protein inhibits the reaction [Streptozocin results in increased expression of POU1F1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of POU1F1 protein]
CTD PMID:29216956 NCBI chr16:65,317,398...65,331,904
Ensembl chr16:65,317,397...65,331,183
JBrowse link
G Pou5f1 POU domain, class 5, transcription factor 1 multiple interactions ISO [bisphenol A co-treated with Streptozocin] results in decreased expression of POU5F1 protein CTD PMID:35187753 NCBI chr17:35,816,929...35,821,674
Ensembl chr17:35,816,915...35,821,669
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha affects response to substance
multiple interactions
decreases expression
increases expression
EXP
ISO
PPARA protein affects the susceptibility to Streptozocin
[Dietary Fats co-treated with Streptozocin] results in decreased expression of PPARA mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of PPARA mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of PPARA protein; [Streptozocin co-treated with Dietary Fats co-treated with Carboxymethylcellulose Sodium] results in decreased expression of PPARA protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARA mRNA; Acrylamide inhibits the reaction [Streptozocin results in increased expression of PPARA mRNA]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PPARA mRNA]; Metformin inhibits the reaction [Streptozocin results in decreased expression of PPARA mRNA]; naringenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Carboxymethylcellulose Sodium] results in decreased expression of PPARA protein]; puerarin inhibits the reaction [Streptozocin results in decreased expression of PPARA mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of PPARA mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of PPARA protein]; TERT protein inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARA mRNA]
[[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of PPARA mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of PPARA mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of PPARA protein; [Streptozocin co-treated with Cadmium] results in decreased expression of PPARA protein; [Streptozocin co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in increased expression of PPARA protein; Allopurinol inhibits the reaction [Streptozocin results in decreased expression of PPARA mRNA]; Allopurinol inhibits the reaction [Streptozocin results in decreased expression of PPARA protein]; Berberine inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in increased expression of PPARA protein]; Bezafibrate inhibits the reaction [Streptozocin results in decreased expression of PPARA mRNA]; Fenofibrate inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in increased expression of PPARA protein]; idebenone inhibits the reaction [Streptozocin results in increased expression of PPARA protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of PPARA protein]; Plant Extracts inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PPARA mRNA]; Plant Extracts inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PPARA protein]; Quercetin inhibits the reaction [Streptozocin results in decreased expression of PPARA mRNA]; Quercetin inhibits the reaction [Streptozocin results in decreased expression of PPARA protein]
Streptozocin results in decreased expression of PPARA mRNA; Streptozocin results in decreased expression of PPARA protein
CTD PMID:12967931 PMID:16306367 PMID:18338635 PMID:23647015 PMID:23927877 More... NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020
JBrowse link
G Ppard peroxisome proliferator activator receptor delta multiple interactions
decreases expression
ISO
EXP
[Streptozocin co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in increased expression of PPARD protein; Berberine inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in increased expression of PPARD protein]; Fenofibrate inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in increased expression of PPARD protein]; Olive Oil inhibits the reaction [Streptozocin results in decreased expression of PPARD mRNA]
[Streptozocin co-treated with Dietary Fats co-treated with Carboxymethylcellulose Sodium] results in decreased expression of PPARB protein; naringenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Carboxymethylcellulose Sodium] results in decreased expression of PPARB protein]
CTD PMID:18338635 PMID:25246140 PMID:31063766 NCBI chr17:28,451,715...28,520,446
Ensembl chr17:28,451,674...28,520,448
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma multiple interactions
decreases expression
increases expression
EXP
ISO
[Dietary Fats co-treated with Streptozocin] results in decreased expression of PPARG mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of PPARG mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of PPARG mRNA; [Streptozocin co-treated with Dietary Fats co-treated with Carboxymethylcellulose Sodium] results in decreased expression of PPARG protein; [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of PPARG protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARG mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARG protein; esculetin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of PPARG mRNA]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PPARG mRNA]; MIR29A mRNA inhibits the reaction [Streptozocin results in decreased expression of PPARG mRNA]; MIR29A mRNA inhibits the reaction [Streptozocin results in decreased expression of PPARG protein]; naringenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Carboxymethylcellulose Sodium] results in decreased expression of PPARG protein]; Telmisartan inhibits the reaction [Streptozocin results in decreased expression of PPARG protein]; TERT protein inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARG mRNA]
Streptozocin results in decreased expression of PPARG mRNA; Streptozocin results in decreased expression of PPARG protein
Streptozocin results in increased expression of PPARG mRNA; Streptozocin results in increased expression of PPARG protein
2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of PPARG protein]; [Streptozocin co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in decreased expression of PPARG protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARG mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARG protein; [Streptozocin co-treated with Isoproterenol] affects the expression of PPARG protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of PPARG protein; allyl isothiocyanate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARG protein]; Berberine inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in decreased expression of PPARG protein]; Bezafibrate inhibits the reaction [Streptozocin results in decreased expression of PPARG mRNA]; bisphenol A diglycidyl ether inhibits the reaction [Calcitriol inhibits the reaction [Streptozocin results in decreased expression of PPARG mRNA]]; bisphenol A diglycidyl ether inhibits the reaction [Calcitriol inhibits the reaction [Streptozocin results in decreased expression of PPARG protein]]; Calcitriol inhibits the reaction [Streptozocin results in decreased expression of PPARG mRNA]; Calcitriol inhibits the reaction [Streptozocin results in decreased expression of PPARG protein]; chebulagic acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARG protein]; esculetin inhibits the reaction [Streptozocin results in decreased expression of PPARG protein]; esculetin inhibits the reaction [Streptozocin results in increased expression of PPARG protein]; eupafolin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of PPARG protein]; Ficusin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARG mRNA]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of PPARG mRNA]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of PPARG protein]; Hesperidin inhibits the reaction [2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of PPARG protein]]; Hesperidin inhibits the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of PPARG protein]; INS protein promotes the reaction [Streptozocin results in increased expression of PPARG mRNA]; mangiferin inhibits the reaction [Streptozocin results in decreased expression of PPARG mRNA]; mangiferin inhibits the reaction [Streptozocin results in decreased expression of PPARG protein]; naringenin inhibits the reaction [Streptozocin results in decreased expression of PPARG mRNA]; naringenin inhibits the reaction [Streptozocin results in decreased expression of PPARG protein]; Olive Oil inhibits the reaction [Streptozocin results in decreased expression of PPARG mRNA]; Pioglitazone inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARG mRNA]; Pioglitazone inhibits the reaction [Streptozocin results in decreased expression of PPARG protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of PPARG protein]; Rosiglitazone inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in decreased expression of PPARG protein]; Rosiglitazone inhibits the reaction [Streptozocin results in decreased expression of PPARG]
Streptozocin results in decreased expression of PPARG; Streptozocin results in decreased expression of PPARG mRNA; Streptozocin results in decreased expression of PPARG protein
CTD PMID:12967931 PMID:16980342 PMID:18338635 PMID:20219977 PMID:21381899 More... NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360
JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha decreases expression
multiple interactions
increases expression
EXP
ISO
Streptozocin results in decreased expression of PPARGC1A protein
[Dietary Fats co-treated with Streptozocin] results in decreased expression of PPARGC1A mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARGC1A mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARGC1A protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of PPARGC1A mRNA; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARGC1A protein]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PPARGC1A mRNA]; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of PPARGC1A mRNA]; Telmisartan inhibits the reaction [Streptozocin results in decreased expression of PPARGC1A protein]; TERT protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARGC1A protein]; TERT protein inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARGC1A mRNA]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARGC1A mRNA]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARGC1A protein]
Streptozocin results in increased expression of PPARGC1A mRNA
Streptozocin results in decreased expression of PPARGC1A mRNA; Streptozocin results in decreased expression of PPARGC1A protein
ferulic acid inhibits the reaction [Streptozocin results in decreased expression of PPARGC1A protein]; Olive Oil inhibits the reaction [Streptozocin results in decreased expression of PPARGC1A mRNA]; STUB1 inhibits the reaction [Streptozocin results in decreased expression of PPARGC1A protein]
CTD PMID:21381899 PMID:23319174 PMID:25246140 PMID:26522834 PMID:31029786 More... NCBI chr 5:51,611,591...52,273,316
Ensembl chr 5:51,611,592...51,725,068
JBrowse link
G Ppfia3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of PPFIA3 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of PPFIA3 mRNA] CTD PMID:33484791 NCBI chr 7:44,988,550...45,016,443
Ensembl chr 7:44,988,546...45,016,443
JBrowse link
G Ppid peptidylprolyl isomerase D (cyclophilin D) increases expression
multiple interactions
ISO Streptozocin results in increased expression of PPID protein
Phosphocreatine inhibits the reaction [Streptozocin results in increased expression of PPID protein]
CTD PMID:34455488 NCBI chr 3:79,498,644...79,511,117
Ensembl chr 3:79,498,649...79,510,957
JBrowse link
G Ppp1r12a protein phosphatase 1, regulatory subunit 12A multiple interactions
increases expression
ISO [Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of PPP1R12A protein; Angiotensin-Converting Enzyme Inhibitors inhibits the reaction [Streptozocin results in increased expression of PPP1R12A protein modified form]; fasudil inhibits the reaction [Streptozocin results in increased expression of PPP1R12A protein modified form] CTD PMID:20665664 PMID:22429817 NCBI chr10:107,997,913...108,115,846
Ensembl chr10:107,998,054...108,120,336
JBrowse link
G Ppp1r3c protein phosphatase 1, regulatory subunit 3C decreases expression ISO Streptozocin results in decreased expression of PPP1R3C mRNA CTD PMID:25905778 NCBI chr19:36,709,131...36,714,004
Ensembl chr19:36,709,131...36,714,053
JBrowse link
G Ppp2ca protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform multiple interactions
decreases methylation
decreases expression
EXP 5-Methoxypsoralen inhibits the reaction [Streptozocin results in decreased expression of PPP2CA protein modified form]; Folic Acid deficiency promotes the reaction [Streptozocin results in decreased methylation of PPP2CA protein]; Folic Acid inhibits the reaction [Streptozocin results in decreased methylation of PPP2CA protein]; INS1 protein affects the reaction [Streptozocin results in decreased methylation of PPP2CA protein]; Tadalafil inhibits the reaction [Streptozocin results in decreased expression of PPP2CA protein modified form] CTD PMID:28422052 PMID:34428446 NCBI chr11:51,989,651...52,013,576
Ensembl chr11:51,989,508...52,018,605
JBrowse link
G Ppy pancreatic polypeptide multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of PPY mRNA CTD PMID:33484791 NCBI chr11:101,990,757...101,992,145
Ensembl chr11:101,990,756...101,992,145
JBrowse link
G Prdx1 peroxiredoxin 1 multiple interactions
decreases expression
ISO
EXP
PRDX4 protein inhibits the reaction [Streptozocin results in decreased expression of PRDX1 mRNA] CTD PMID:20446767 NCBI chr 4:116,542,796...116,557,196
Ensembl chr 4:116,542,741...116,558,019
JBrowse link
G Prdx2 peroxiredoxin 2 decreases expression
multiple interactions
EXP
ISO
Streptozocin results in decreased expression of PRDX2 mRNA
PRDX4 protein inhibits the reaction [Streptozocin results in decreased expression of PRDX2 mRNA]
CTD PMID:20446767 NCBI chr 8:85,696,251...85,701,440
Ensembl chr 8:85,696,216...85,701,463
JBrowse link
G Prdx3 peroxiredoxin 3 multiple interactions
decreases expression
ISO
EXP
PRDX4 protein inhibits the reaction [Streptozocin results in decreased expression of PRDX3 mRNA] CTD PMID:20446767 NCBI chr19:60,852,504...60,862,976
Ensembl chr19:60,852,489...60,862,994
JBrowse link
G Prdx4 peroxiredoxin 4 multiple interactions
decreases expression
ISO
EXP
PRDX4 protein inhibits the reaction [Streptozocin results in decreased expression of PRDX1 mRNA]; PRDX4 protein inhibits the reaction [Streptozocin results in decreased expression of PRDX2 mRNA]; PRDX4 protein inhibits the reaction [Streptozocin results in decreased expression of PRDX3 mRNA]; PRDX4 protein inhibits the reaction [Streptozocin results in decreased expression of PRDX4 mRNA]; PRDX4 protein inhibits the reaction [Streptozocin results in decreased expression of PRDX5 mRNA]; PRDX4 protein inhibits the reaction [Streptozocin results in decreased expression of PRDX6 mRNA]; PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of MMP2 mRNA]; PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of MMP3 mRNA]; PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of MMP7 mRNA]; PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of MMP9 mRNA]; PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]
[Dietary Fats co-treated with Streptozocin] results in decreased expression of PRDX4 mRNA; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PRDX4 mRNA]
CTD PMID:20446767 PMID:33359794 NCBI chr  X:154,106,914...154,125,268
Ensembl chr  X:154,106,914...154,123,750
JBrowse link
G Prdx5 peroxiredoxin 5 decreases expression
multiple interactions
EXP
ISO
Streptozocin results in decreased expression of PRDX5 mRNA
PRDX4 protein inhibits the reaction [Streptozocin results in decreased expression of PRDX5 mRNA]
CTD PMID:20446767 NCBI chr19:6,884,065...6,887,474
Ensembl chr19:6,884,065...6,887,474
JBrowse link
G Prdx6 peroxiredoxin 6 multiple interactions
decreases expression
ISO
EXP
PRDX4 protein inhibits the reaction [Streptozocin results in decreased expression of PRDX6 mRNA] CTD PMID:20446767 NCBI chr 1:161,067,682...161,078,780
Ensembl chr 1:161,067,682...161,078,789
JBrowse link
G Prkaa1 protein kinase, AMP-activated, alpha 1 catalytic subunit multiple interactions ISO
EXP
Streptozocin results in decreased expression of and results in decreased phosphorylation of PRKAA1 protein; STUB1 inhibits the reaction [Streptozocin results in decreased expression of and results in decreased phosphorylation of PRKAA1 protein]
[Streptozocin co-treated with Dietary Fats] results in decreased expression of and results in decreased phosphorylation of PRKAA1 protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of PRKAA1 mRNA; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of and results in decreased phosphorylation of PRKAA1 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PRKAA1 mRNA]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of and results in decreased phosphorylation of PRKAA1 protein]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PRKAA1 mRNA]
CTD PMID:35442559 PMID:37337224 NCBI chr15:5,172,641...5,211,380
Ensembl chr15:5,173,343...5,211,380
JBrowse link
G Prkaa2 protein kinase, AMP-activated, alpha 2 catalytic subunit multiple interactions ISO
EXP
streptozocin decreases expression and phosphorylation of Prkaa2 protein in liver
[Streptozocin co-treated with Dietary Fats] results in decreased expression of PRKAA2 mRNA; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PRKAA2 mRNA]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PRKAA2 mRNA]
CTD
RGD
PMID:37337224 PMID:32535406 RGD:401850547 NCBI chr 4:104,886,846...104,967,095
Ensembl chr 4:104,887,071...104,967,087
JBrowse link
G Prkaca protein kinase, cAMP dependent, catalytic, alpha multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased phosphorylation of PRKACA protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased phosphorylation of PRKACA protein] CTD PMID:32303808 NCBI chr 8:84,699,607...84,723,073
Ensembl chr 8:84,699,622...84,723,072
JBrowse link
G Prkca protein kinase C, alpha multiple interactions
increases expression
ISO Ethanol inhibits the reaction [Streptozocin results in increased expression of PRKCA protein]; procyanidin B2 inhibits the reaction [Streptozocin results in increased expression of PRKCA protein] CTD PMID:12198386 PMID:25199697 NCBI chr11:107,824,213...108,237,360
Ensembl chr11:107,824,213...108,234,754
JBrowse link
G Prkcb protein kinase C, beta increases phosphorylation
multiple interactions
ISO Streptozocin results in increased phosphorylation of PRKCB protein
Streptozocin results in increased expression of and results in increased activity of PRKCB protein; tempol inhibits the reaction [Streptozocin results in increased expression of and results in increased activity of PRKCB protein]
CTD PMID:16478977 PMID:16980342 NCBI chr 7:121,888,327...122,233,625
Ensembl chr 7:121,887,974...122,233,625
JBrowse link
G Prkcd protein kinase C, delta multiple interactions
increases expression
ISO arjunolic acid inhibits the reaction [Streptozocin results in increased expression of PRKCD protein]; Ethanol inhibits the reaction [Streptozocin results in increased expression of PRKCD protein]; Streptozocin results in increased expression of and results in increased activity of PRKCD protein; tempol inhibits the reaction [Streptozocin results in increased expression of and results in increased activity of PRKCD protein] CTD PMID:12198386 PMID:16478977 PMID:19682444 NCBI chr14:30,317,310...30,348,637
Ensembl chr14:30,317,311...30,348,167
JBrowse link
G Prkce protein kinase C, epsilon multiple interactions
increases expression
ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of PRKCE mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of PRKCE protein; arjunolic acid inhibits the reaction [Streptozocin results in increased expression of PRKCE protein]; Ethanol inhibits the reaction [Streptozocin results in increased expression of PRKCE protein] CTD PMID:12198386 PMID:19682444 PMID:20665664 NCBI chr17:86,472,631...86,965,347
Ensembl chr17:86,475,213...86,965,347
JBrowse link
G Prkg1 protein kinase, cGMP-dependent, type I multiple interactions
decreases expression
EXP 5-Methoxypsoralen inhibits the reaction [Streptozocin results in decreased expression of PRKG1 protein]; Tadalafil inhibits the reaction [Streptozocin results in decreased expression of PRKG1 protein] CTD PMID:34428446 NCBI chr19:30,541,887...31,742,675
Ensembl chr19:30,541,889...31,742,433
JBrowse link
G Prkg2 protein kinase, cGMP-dependent, type II multiple interactions ISO [ALPK1 protein results in increased susceptibility to Streptozocin] which results in decreased expression of PRKG2 mRNA CTD PMID:27542954 NCBI chr 5:99,077,632...99,185,042
Ensembl chr 5:99,077,632...99,185,210
JBrowse link
G Prok1 prokineticin 1 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of PROK1 mRNA CTD PMID:29127188 NCBI chr 3:107,139,232...107,147,023
Ensembl chr 3:107,140,113...107,147,023
JBrowse link
G Prok2 prokineticin 2 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of PROK2 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of PROK2 mRNA] CTD PMID:33484791 NCBI chr 6:99,687,833...99,703,368
Ensembl chr 6:99,688,260...99,703,353
JBrowse link
G Prph peripherin decreases expression ISO Streptozocin results in decreased expression of PRPH protein CTD PMID:30583000 NCBI chr15:98,951,452...98,956,858
Ensembl chr15:98,953,055...98,956,859
JBrowse link
G Prtn3 proteinase 3 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of PRTN3 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of PRTN3 mRNA] CTD PMID:33484791 NCBI chr10:79,715,499...79,719,008
Ensembl chr10:79,710,310...79,719,008
JBrowse link
G Psd2 pleckstrin and Sec7 domain containing 2 multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of PSD2 mRNA CTD PMID:33484791 NCBI chr18:36,075,480...36,147,768
Ensembl chr18:36,097,883...36,147,768
JBrowse link
G Psrc1 proline/serine-rich coiled-coil 1 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of PSRC1 mRNA CTD PMID:29127188 NCBI chr 3:108,291,120...108,295,547
Ensembl chr 3:108,291,155...108,295,547
JBrowse link
G Pten phosphatase and tensin homolog increases expression
multiple interactions
ISO Streptozocin results in increased expression of PTEN mRNA; Streptozocin results in increased expression of PTEN protein
Phycocyanin inhibits the reaction [Streptozocin results in increased expression of PTEN mRNA]; Rivastigmine inhibits the reaction [Streptozocin results in increased expression of PTEN mRNA]; Wortmannin inhibits the reaction [Phycocyanin inhibits the reaction [Streptozocin results in increased expression of PTEN mRNA]]
CTD PMID:32805344 PMID:38706688 NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 multiple interactions
increases expression
ISO [resveratrol co-treated with Streptozocin] results in increased expression of PTGS1 mRNA; acetovanillone inhibits the reaction [Streptozocin results in increased expression of PTGS1 protein] CTD PMID:12888618 PMID:18414395 PMID:25905778 NCBI chr 2:36,106,758...36,142,287
Ensembl chr 2:36,120,438...36,142,284
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
increases activity
ISO
EXP
[1-((4-methylsulfonyl)phenyl)-3-trifluoromethyl-5-(4-fluorophenyl)pyrazole binds to and results in decreased activity of PTGS2 protein] which results in decreased susceptibility to Streptozocin; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of PTGS2 mRNA; [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide binds to and results in decreased activity of PTGS2 protein] which results in decreased susceptibility to Streptozocin; [Telmisartan co-treated with Aspirin] inhibits the reaction [Streptozocin results in increased expression of PTGS2 protein]; acetovanillone inhibits the reaction [Streptozocin results in increased expression of PTGS2 protein]; Aspirin inhibits the reaction [Streptozocin results in increased expression of PTGS2 protein]; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of PTGS2 mRNA]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of PTGS2 mRNA]; Glyburide inhibits the reaction [Streptozocin results in increased expression of PTGS2 mRNA]; IGF2R protein modified form promotes the reaction [Streptozocin results in increased expression of PTGS2 protein]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of PTGS2 mRNA]; Kangen-karyu inhibits the reaction [Streptozocin results in increased expression of PTGS2 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of PTGS2 mRNA]; Rosiglitazone inhibits the reaction [Streptozocin results in increased expression of PTGS2 mRNA]; Rosiglitazone inhibits the reaction [Streptozocin results in increased expression of PTGS2 protein]; Zinc inhibits the reaction [Streptozocin results in increased expression of PTGS2 mRNA]
Streptozocin results in increased expression of PTGS2 mRNA; Streptozocin results in increased expression of PTGS2 protein
Acrylamide promotes the reaction [Streptozocin results in increased expression of PTGS2 protein]; asiatic acid inhibits the reaction [Streptozocin results in increased activity of PTGS2 protein]; asiatic acid promotes the reaction [Carnosine inhibits the reaction [Streptozocin results in increased activity of PTGS2 protein]]; Carnosine inhibits the reaction [Streptozocin results in increased activity of PTGS2 protein]; Carnosine promotes the reaction [asiatic acid inhibits the reaction [Streptozocin results in increased activity of PTGS2 protein]]; NTN1 protein inhibits the reaction [Streptozocin results in increased expression of PTGS2 protein]
CTD PMID:12888618 PMID:14514642 PMID:17112505 PMID:18414395 PMID:19397970 More... NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 multiple interactions
increases expression
EXP resveratrol inhibits the reaction [Streptozocin results in increased expression of PTPN1 protein] CTD PMID:25808216 NCBI chr 2:167,772,670...167,821,305
Ensembl chr 2:167,773,977...167,821,305
JBrowse link
G Ptprd protein tyrosine phosphatase receptor type D multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of PTPRD mRNA CTD PMID:20665664 NCBI chr 4:75,859,474...78,132,282
Ensembl chr 4:75,859,475...78,130,198
JBrowse link
G Ptprm protein tyrosine phosphatase receptor type M multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of PTPRM mRNA CTD PMID:20665664 NCBI chr17:66,973,843...67,661,486
Ensembl chr17:66,973,942...67,661,452
JBrowse link
G Ptprt protein tyrosine phosphatase receptor type T multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of PTPRT mRNA CTD PMID:20665664 NCBI chr 2:161,363,908...162,503,106
Ensembl chr 2:161,363,910...162,503,067
JBrowse link
G Pycard PYD and CARD domain containing multiple interactions
increases expression
ISO
EXP
Allopurinol inhibits the reaction [Streptozocin results in increased expression of PYCARD mRNA]; Allopurinol inhibits the reaction [Streptozocin results in increased expression of PYCARD protein]; palbinone inhibits the reaction [Streptozocin results in increased expression of PYCARD protein]; Quercetin inhibits the reaction [Streptozocin results in increased expression of PYCARD mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of PYCARD protein]
Streptozocin results in increased expression of PYCARD mRNA; Streptozocin results in increased expression of PYCARD protein
[Streptozocin co-treated with Dextran Sulfate] results in increased expression of PYCARD protein
CTD PMID:23647015 PMID:32202043 PMID:34964214 NCBI chr 7:127,590,545...127,593,039
Ensembl chr 7:127,588,880...127,593,039
JBrowse link
G Pygl liver glycogen phosphorylase multiple interactions
decreases expression
ISO [Streptozocin co-treated with Niacinamide] affects the activity of PYGL protein; resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] affects the activity of PYGL protein]
Streptozocin results in decreased expression of PYGL mRNA
CTD PMID:19059388 PMID:25905778 NCBI chr12:70,237,589...70,274,457
Ensembl chr12:70,237,585...70,278,262
JBrowse link
G Pygm muscle glycogen phosphorylase multiple interactions
decreases activity
ISO Plant Extracts inhibits the reaction [Streptozocin results in decreased activity of PYGM protein]; Polysaccharides inhibits the reaction [Streptozocin results in decreased activity of PYGM protein] CTD PMID:26616445 NCBI chr19:6,434,438...6,448,494
Ensembl chr19:6,434,429...6,448,489
JBrowse link
G Pyroxd2 pyridine nucleotide-disulphide oxidoreductase domain 2 increases expression
multiple interactions
ISO Streptozocin results in increased expression of PYROXD2 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of PYROXD2 protein]
CTD PMID:19634143 NCBI chr19:42,714,296...42,741,261
Ensembl chr19:42,714,297...42,741,214
JBrowse link
G Pyy peptide YY multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of PYY mRNA CTD PMID:33484791 NCBI chr11:101,997,502...101,998,658
Ensembl chr11:101,997,502...101,998,658
JBrowse link
G Rac1 Rac family small GTPase 1 multiple interactions
increases activity
EXP
ISO
Atorvastatin inhibits the reaction [Streptozocin results in increased activity of and results in increased localization of RAC1 protein]; Streptozocin results in increased activity of and results in increased localization of RAC1 protein
Atorvastatin inhibits the reaction [Streptozocin results in increased activity of RAC1 protein]
CTD PMID:17279352 PMID:17589825 NCBI chr 5:143,491,236...143,513,786
Ensembl chr 5:143,489,389...143,513,791
JBrowse link
G Rac2 Rac family small GTPase 2 multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of RAC2 mRNA CTD PMID:25905778 NCBI chr15:78,443,369...78,456,983
Ensembl chr15:78,443,367...78,456,983
JBrowse link
G Raf1 v-raf-leukemia viral oncogene 1 multiple interactions
increases expression
decreases expression
ISO manumycin inhibits the reaction [Streptozocin results in increased expression of RAF1 protein]; Simvastatin inhibits the reaction [Streptozocin results in increased expression of RAF1 protein]; xanthoceraside inhibits the reaction [Streptozocin results in decreased expression of RAF1 protein] CTD PMID:18569938 PMID:23562514 NCBI chr 6:115,595,530...115,653,596
Ensembl chr 6:115,595,028...115,653,596
JBrowse link
G Rasgrf1 RAS protein-specific guanine nucleotide-releasing factor 1 affects localization ISO Streptozocin affects the localization of RASGRF1 protein CTD PMID:19002579 NCBI chr 9:89,791,565...89,909,032
Ensembl chr 9:89,791,961...89,909,030
JBrowse link
G Rasgrp2 RAS, guanyl releasing protein 2 multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of RASGRP2 mRNA CTD PMID:25905778 NCBI chr19:6,449,038...6,465,243
Ensembl chr19:6,449,370...6,465,246
JBrowse link
G Rbm39 RNA binding motif protein 39 decreases expression ISO Streptozocin results in decreased expression of RBM39 mRNA CTD PMID:25905778 NCBI chr 2:155,989,159...156,022,649
Ensembl chr 2:155,989,159...156,022,158
JBrowse link
G Rbp4 retinol binding protein 4, plasma multiple interactions ISO [Dietary Fats co-treated with Streptozocin] results in increased secretion of RBP4 protein; Berberine inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased secretion of RBP4 protein]; cinnamaldehyde inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased secretion of RBP4 protein]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased secretion of RBP4 protein] CTD PMID:19080170 NCBI chr19:38,105,068...38,113,769
Ensembl chr19:38,105,077...38,113,729
JBrowse link
G Rbpjl recombination signal binding protein for immunoglobulin kappa J region-like multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of RBPJL mRNA CTD PMID:33484791 NCBI chr 2:164,244,996...164,257,368
Ensembl chr 2:164,245,061...164,257,368
JBrowse link
G Rdh1 retinol dehydrogenase 1 (all trans) multiple interactions ISO [Resveratrol co-treated with Streptozocin] results in decreased expression of RDH2 mRNA CTD PMID:25905778 NCBI chr10:127,595,595...127,604,168
Ensembl chr10:127,595,590...127,604,166
JBrowse link
G Rel reticuloendotheliosis oncogene multiple interactions ISO Streptozocin affects the localization of and results in increased activity of REL protein CTD PMID:19002579 NCBI chr11:23,686,847...23,720,969
Ensembl chr11:23,686,847...23,720,970
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions
increases expression
increases phosphorylation
affects localization
increases activity
increases localization
ISO
EXP
TNF protein inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]
Streptozocin results in increased expression of RELA mRNA; Streptozocin results in increased expression of RELA protein; Streptozocin results in increased expression of RELA protein modified form
Streptozocin results in increased phosphorylation of RELA protein
2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased phosphorylation of RELA protein]; 5-Methoxypsoralen inhibits the reaction [Streptozocin results in increased expression of RELA protein modified form]; [Streptozocin co-treated with Dextran Sulfate] results in increased phosphorylation of RELA protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of RELA mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of RELA protein; [Streptozocin co-treated with Niacinamide] results in increased phosphorylation of RELA protein; AICA ribonucleotide inhibits the reaction [Streptozocin results in increased phosphorylation of and results in increased activity of RELA protein]; asiatic acid inhibits the reaction [Streptozocin results in increased expression of RELA protein]; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of RELA mRNA]; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of RELA protein]; Carnosine inhibits the reaction [Streptozocin results in increased expression of RELA protein]; Carnosine promotes the reaction [asiatic acid inhibits the reaction [Streptozocin results in increased expression of RELA protein]]; EPHX2 gene mutant form inhibits the reaction [Streptozocin results in increased activity of RELA protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased phosphorylation of RELA protein]; montelukast inhibits the reaction [Streptozocin results in increased expression of and affects the localization of RELA protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Streptozocin promotes the reaction [RELA protein binds to MMP9 promoter]]; NTN1 protein inhibits the reaction [Streptozocin results in increased expression of RELA protein]; Resveratrol inhibits the reaction [Streptozocin results in increased phosphorylation of and results in increased activity of RELA protein]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of RELA protein]; SIRT1 protein inhibits the reaction [Streptozocin promotes the reaction [RELA protein binds to PARP1 protein]]; Streptozocin promotes the reaction [RELA protein binds to MMP9 promoter]; Streptozocin promotes the reaction [RELA protein binds to PARP1 protein]; Streptozocin results in increased expression of and affects the localization of RELA protein; Streptozocin results in increased phosphorylation of and results in increased activity of RELA protein; Tadalafil inhibits the reaction [Streptozocin results in increased expression of RELA protein modified form]
3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]; 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of RELA protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of RELA protein; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of RELA protein; [Niacinamide co-treated with Streptozocin] results in increased expression of RELA protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of RELA protein; [Streptozocin co-treated with Niacinamide] results in increased activity of RELA protein; [Streptozocin co-treated with Niacinamide] results in increased expression of RELA protein; [Telmisartan co-treated with Aspirin] inhibits the reaction [Streptozocin results in increased expression of RELA protein]; AC3056 inhibits the reaction [Streptozocin results in increased expression of RELA protein]; Angiotensin Receptor Antagonists inhibits the reaction [Streptozocin results in increased expression of RELA protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased expression of RELA protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased phosphorylation of RELA protein]; Aspirin inhibits the reaction [Streptozocin results in increased expression of RELA protein]; benazepril inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of RELA protein]; bisphenol A diglycidyl ether inhibits the reaction [Calcitriol inhibits the reaction [Streptozocin results in increased expression of and results in decreased phosphorylation of RELA protein]]; Calcitriol inhibits the reaction [Streptozocin results in increased expression of and results in decreased phosphorylation of RELA protein]; chromium mesoporphyrin inhibits the reaction [Hemin inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]]; crocin inhibits the reaction [Streptozocin results in increased expression of RELA protein]; Curcumin inhibits the reaction [Streptozocin affects the localization of RELA protein]; Diosgenin inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]; Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of RELA protein]; fasudil inhibits the reaction [Streptozocin results in increased expression of and affects the localization of RELA protein]; Gallic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of RELA protein]; Gliclazide inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in increased expression of RELA protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of RELA protein]; Gliclazide inhibits the reaction [Streptozocin results in increased expression of RELA protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of RELA protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]; Glyburide inhibits the reaction [Streptozocin results in increased expression of RELA protein]; Hemin inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]; IGF2R protein modified form promotes the reaction [Streptozocin results in increased expression of RELA protein modified form]; mangiferin inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]; nifuroxazide inhibits the reaction [Streptozocin results in increased localization of RELA protein]; Phycocyanin inhibits the reaction [Streptozocin results in increased expression of RELA protein]; pinitol inhibits the reaction [Streptozocin results in increased expression of RELA protein]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]; piperlongumine inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]; Plant Extracts inhibits the reaction [Streptozocin results in increased expression of RELA protein]; Resveratrol inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in increased expression of RELA protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased activity of RELA protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of RELA protein]; Rivastigmine inhibits the reaction [Streptozocin results in increased expression of RELA protein]; Streptozocin affects the localization of and results in decreased activity of RELA protein; Streptozocin promotes the reaction [IGF2R protein modified form results in increased expression of RELA protein modified form]; Streptozocin results in increased expression of and affects the localization of RELA protein; Streptozocin results in increased expression of and results in decreased phosphorylation of RELA protein; Streptozocin results in increased expression of and results in increased phosphorylation of RELA protein; STUB1 inhibits the reaction [Streptozocin results in increased phosphorylation of RELA protein]; Tropisetron inhibits the reaction [Streptozocin results in increased expression of RELA protein]; Wortmannin inhibits the reaction [Phycocyanin inhibits the reaction [Streptozocin results in increased expression of RELA protein]]; Zinc inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]
CTD PMID:17900838 PMID:19002579 PMID:19040617 PMID:19123331 PMID:19133311 More... NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Retn resistin multiple interactions
increases expression
ISO resveratrol inhibits the reaction [Streptozocin results in increased expression of RETN protein] CTD PMID:26071184 NCBI chr 8:3,705,770...3,709,818
Ensembl chr 8:3,705,770...3,710,110
JBrowse link
G Rhbdf2 rhomboid 5 homolog 2 increases expression
multiple interactions
ISO Streptozocin results in increased expression of RHBDF2 mRNA; Streptozocin results in increased expression of RHBDF2 protein
Diosgenin inhibits the reaction [Streptozocin results in increased expression of RHBDF2 mRNA]; Diosgenin inhibits the reaction [Streptozocin results in increased expression of RHBDF2 protein]
CTD PMID:35305976 NCBI chr11:116,488,991...116,517,786
Ensembl chr11:116,488,991...116,517,845
JBrowse link
G Rhoa ras homolog family member A multiple interactions
increases activity
increases expression
ISO [Resveratrol co-treated with Ramipril] inhibits the reaction [Streptozocin results in increased expression of RHOA protein]; Atorvastatin inhibits the reaction [Streptozocin results in increased activity of RHOA protein]; Ramipril inhibits the reaction [Streptozocin results in increased expression of RHOA protein] CTD PMID:17589825 PMID:23376009 PMID:31062909 NCBI chr 9:108,183,359...108,215,142
Ensembl chr 9:108,183,328...108,215,133
JBrowse link
G Rnf2 ring finger protein 2 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of RNF2 mRNA CTD PMID:28946194 NCBI chr 1:151,345,159...151,376,562
Ensembl chr 1:151,333,755...151,376,706
JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 multiple interactions
increases expression
increases activity
ISO fasudil inhibits the reaction [Streptozocin results in increased activity of ROCK1 protein]; fasudil inhibits the reaction [Streptozocin results in increased expression of ROCK1 mRNA]
Streptozocin results in increased expression of ROCK1 mRNA; Streptozocin results in increased expression of ROCK1 protein
CTD PMID:22429817 PMID:23376009 PMID:31062909 NCBI chr18:10,064,401...10,182,225
Ensembl chr18:10,064,401...10,182,045
JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 increases expression
multiple interactions
ISO Streptozocin results in increased expression of ROCK2 protein
[Resveratrol co-treated with Ramipril] inhibits the reaction [Streptozocin results in increased expression of ROCK2 protein]; Ramipril inhibits the reaction [Streptozocin results in increased expression of ROCK2 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of ROCK2 protein]
CTD PMID:31062909 NCBI chr12:16,944,808...17,038,275
Ensembl chr12:16,944,896...17,037,824
JBrowse link
G Rpl18a ribosomal protein L18A increases expression
multiple interactions
ISO Streptozocin results in increased expression of RPL18A mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of RPL18A mRNA]
CTD PMID:16684804 NCBI chr 8:71,347,366...71,350,087
Ensembl chr 8:71,347,366...71,350,056
JBrowse link
G Rprm reprimo, TP53 dependent G2 arrest mediator candidate multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of RPRM mRNA CTD PMID:25905778 NCBI chr 2:53,974,105...53,975,564
Ensembl chr 2:53,974,105...53,975,564
JBrowse link
G Rps3 ribosomal protein S3 increases expression
multiple interactions
ISO Streptozocin results in increased expression of RPS3 mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of RPS3 mRNA]
CTD PMID:16684804 NCBI chr 7:99,127,103...99,132,916
Ensembl chr 7:99,127,103...99,132,945
JBrowse link
G Rrad Ras-related associated with diabetes increases expression
multiple interactions
ISO Streptozocin results in increased expression of RRAD mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of RRAD mRNA]
CTD PMID:16684804 NCBI chr 8:105,354,702...105,357,921
Ensembl chr 8:105,354,702...105,357,959
JBrowse link
G Runx2 runt related transcription factor 2 decreases expression ISO Streptozocin results in decreased expression of RUNX2 mRNA CTD PMID:25617479 NCBI chr17:44,806,873...45,125,518
Ensembl chr17:44,806,874...45,125,684
JBrowse link
G Rwdd2a RWD domain containing 2A multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of RWDD2A mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of RWDD2A mRNA] CTD PMID:33484791 NCBI chr 9:86,454,041...86,456,952
Ensembl chr 9:86,454,044...86,456,952
JBrowse link
G Ryr2 ryanodine receptor 2, cardiac decreases activity
multiple interactions
decreases expression
ISO
EXP
Streptozocin results in decreased activity of RYR2 protein
[octylphenol co-treated with Streptozocin] results in increased expression of RYR2 mRNA
Triterpenes inhibits the reaction [Streptozocin results in decreased expression of RYR2 mRNA]
CTD PMID:16685413 PMID:19000375 PMID:29935216 NCBI chr13:11,567,985...12,121,831
Ensembl chr13:11,567,988...12,121,831
JBrowse link
G S100a6 S100 calcium binding protein A6 (calcyclin) multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of S100A6 mRNA CTD PMID:25905778 NCBI chr 3:90,520,491...90,531,797
Ensembl chr 3:90,520,189...90,531,488
JBrowse link
G S100a8 S100 calcium binding protein A8 (calgranulin A) multiple interactions
increases expression
EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of S100A8 mRNA; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Streptozocin results in increased expression of S100A8 mRNA] CTD PMID:19833897 PMID:29127188 NCBI chr 3:90,576,378...90,577,341
Ensembl chr 3:90,576,285...90,577,342
JBrowse link
G S100a9 S100 calcium binding protein A9 (calgranulin B) multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of S100A9 mRNA CTD PMID:25905778 NCBI chr 3:90,599,937...90,603,028
Ensembl chr 3:90,599,939...90,603,028
JBrowse link
G S100b S100 protein, beta polypeptide, neural multiple interactions
increases expression
decreases expression
ISO pimagedine inhibits the reaction [Streptozocin results in decreased expression of S100B protein]; pimagedine inhibits the reaction [Streptozocin results in increased expression of S100B protein] CTD PMID:19494442 PMID:20953641 NCBI chr10:76,089,670...76,097,153
Ensembl chr10:76,089,687...76,096,993
JBrowse link
G S1pr2 sphingosine-1-phosphate receptor 2 increases expression ISO Streptozocin results in increased expression of S1PR2 mRNA CTD PMID:22406263 NCBI chr 9:20,877,248...20,888,089
Ensembl chr 9:20,873,657...20,888,077
JBrowse link
G S1pr4 sphingosine-1-phosphate receptor 4 increases expression ISO Streptozocin results in increased expression of S1PR4 mRNA CTD PMID:22406263 NCBI chr10:81,333,579...81,335,971
Ensembl chr10:81,333,581...81,335,966
JBrowse link
G S1pr5 sphingosine-1-phosphate receptor 5 increases expression ISO Streptozocin results in increased expression of S1PR5 mRNA CTD PMID:22406263 NCBI chr 9:21,154,213...21,159,739
Ensembl chr 9:21,154,208...21,159,739
JBrowse link
G Saa1 serum amyloid A 1 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of SAA1 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of SAA1 mRNA] CTD PMID:33484791 NCBI chr 7:46,389,921...46,392,404
Ensembl chr 7:46,389,921...46,392,404
JBrowse link
G Saa2 serum amyloid A 2 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of SAA2 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of SAA2 mRNA] CTD PMID:33484791 NCBI chr 7:46,401,257...46,403,737
Ensembl chr 7:46,401,214...46,403,737
JBrowse link
G Saa3 serum amyloid A 3 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of SAA3 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of SAA3 mRNA] CTD PMID:33484791 NCBI chr 7:46,361,422...46,365,100
Ensembl chr 7:46,361,422...46,365,124
JBrowse link
G Scara5 scavenger receptor class A, member 5 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of SCARA5 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of SCARA5 mRNA] CTD PMID:33484791 NCBI chr14:65,903,852...66,002,275
Ensembl chr14:65,903,852...66,002,275
JBrowse link
G Scd1 stearoyl-Coenzyme A desaturase 1 multiple interactions
increases expression
increases expression
EXP
ISO
[Dietary Fats co-treated with Streptozocin] results in increased expression of SCD1 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of SCD1 mRNA; Acrylamide inhibits the reaction [Streptozocin results in increased expression of SCD1 mRNA]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SCD1 mRNA]
[[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in decreased expression of SCD1 mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of SCD1 mRNA; [Dietary Fats affects the susceptibility to Streptozocin] which results in decreased expression of SCD1 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of SCD1 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of SCD1 mRNA
streptozocin increases expression of Scd protein in liver
CTD
RGD
PMID:29127188 PMID:29988851 PMID:34896238 PMID:35786680 PMID:32535406 RGD:401850547 NCBI chr19:44,382,889...44,396,148
Ensembl chr19:44,382,894...44,396,318
JBrowse link
G Sdha succinate dehydrogenase complex, subunit A, flavoprotein (Fp) increases expression
multiple interactions
ISO Streptozocin results in increased expression of SDHA protein
Trientine inhibits the reaction [Streptozocin results in increased expression of SDHA protein]
CTD PMID:19634143 PMID:21136691 NCBI chr13:74,470,374...74,498,359
Ensembl chr13:74,470,373...74,498,399
JBrowse link
G Sdhb succinate dehydrogenase complex, subunit B, iron sulfur (Ip) multiple interactions
increases expression
ISO
EXP
Trientine inhibits the reaction [Streptozocin results in increased expression of SDHB protein]
[Streptozocin co-treated with Dietary Fats] results in decreased expression of SDHB mRNA; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SDHB mRNA]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SDHB mRNA]
CTD PMID:19634143 PMID:37337224 NCBI chr 4:140,688,582...140,706,509
Ensembl chr 4:140,688,514...140,706,504
JBrowse link
G Sds serine dehydratase multiple interactions ISO [Resveratrol co-treated with Streptozocin] results in decreased expression of SDS mRNA CTD PMID:25905778 NCBI chr 5:120,614,612...120,621,997
Ensembl chr 5:120,614,591...120,621,997
JBrowse link
G Selenop selenoprotein P multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of SELENOP mRNA; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of SELENOP mRNA] CTD PMID:26522834 NCBI chr15:3,300,249...3,309,992
Ensembl chr15:3,298,029...3,309,990
JBrowse link
G Selp selectin, platelet multiple interactions ISO [Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in increased expression of SELP protein]; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in increased expression of SELP protein]] CTD PMID:36547818 NCBI chr 1:163,942,833...163,977,595
Ensembl chr 1:163,942,833...163,977,595
JBrowse link
G Serpina4-ps1 serine (or cysteine) peptidase inhibitor, clade A, member 4, pseudogene 1 multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of SERPINA4-PS1 mRNA CTD PMID:33484791 NCBI chr12:104,044,218...104,053,179
Ensembl chr12:104,046,908...104,052,983
JBrowse link
G Serpina6 serine (or cysteine) peptidase inhibitor, clade A, member 6 multiple interactions ISO [resveratrol co-treated with Streptozocin] results in decreased expression of SERPINA6 mRNA CTD PMID:25905778 NCBI chr12:103,612,889...103,623,477
Ensembl chr12:103,612,889...103,623,471
JBrowse link
G Serpina7 serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of SERPINA7 mRNA CTD PMID:25905778 NCBI chr  X:137,979,998...137,985,985
Ensembl chr  X:137,980,006...137,985,985
JBrowse link
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 multiple interactions
increases expression
EXP
ISO
SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of SERPINE1 mRNA]; SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of SERPINE1]; Streptozocin promotes the reaction [MAP3K5 protein results in increased expression of SERPINE1 protein]; sulforaphane inhibits the reaction [Streptozocin results in increased expression of SERPINE1 protein]
benazepril inhibits the reaction [Streptozocin results in increased expression of SERPINE1 mRNA]; Trientine inhibits the reaction [Streptozocin results in increased expression of SERPINE1 mRNA]; Zinc inhibits the reaction [Streptozocin results in increased expression of SERPINE1 protein]
Streptozocin results in increased expression of SERPINE1 mRNA; Streptozocin results in increased expression of SERPINE1 protein
Streptozocin results in increased expression of SERPINE1; Streptozocin results in increased expression of SERPINE1 mRNA; Streptozocin results in increased expression of SERPINE1 protein
CTD PMID:15322501 PMID:16731828 PMID:16973718 PMID:19369054 PMID:21778425 More... NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122
JBrowse link
G Serpine2 serine (or cysteine) peptidase inhibitor, clade E, member 2 multiple interactions EXP [Dietary Fats co-treated with Streptozocin] results in increased expression of SERPINE2 protein; Rosuvastatin Calcium inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SERPINE2 protein]; sarpogrelate inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SERPINE2 protein] CTD PMID:27097221 NCBI chr 1:79,772,038...79,836,382
Ensembl chr 1:79,771,914...79,838,897
JBrowse link
G Serpinh1 serine (or cysteine) peptidase inhibitor, clade H, member 1 increases expression ISO Streptozocin results in increased expression of SERPINH1 protein CTD PMID:12197670 NCBI chr 7:98,994,583...99,002,321
Ensembl chr 7:98,994,583...99,002,446
JBrowse link
G Setd7 SET domain containing (lysine methyltransferase) 7 multiple interactions ISO Streptozocin promotes the reaction [SETD7 protein binds to CDKN1A promoter] CTD PMID:27652271 NCBI chr 3:51,422,740...51,468,519
Ensembl chr 3:51,422,740...51,468,300
JBrowse link
G Sfxn1 sideroflexin 1 multiple interactions
increases expression
ISO Trientine inhibits the reaction [Streptozocin results in increased expression of SFXN1 protein] CTD PMID:19634143 NCBI chr13:54,225,675...54,262,365
Ensembl chr13:54,225,888...54,262,361
JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 increases expression EXP Streptozocin results in increased expression of SGK1 mRNA; Streptozocin results in increased expression of SGK1 protein CTD PMID:16116964 NCBI chr10:21,758,083...21,875,802
Ensembl chr10:21,758,083...21,875,802
JBrowse link
G Sgk2 serum/glucocorticoid regulated kinase 2 increases expression EXP Streptozocin results in increased expression of SGK2 mRNA CTD PMID:16116964 NCBI chr 2:162,829,249...162,856,059
Ensembl chr 2:162,829,250...162,856,047
JBrowse link
G Sgk3 serum/glucocorticoid regulated kinase 3 increases expression EXP Streptozocin results in increased expression of SGK3 mRNA CTD PMID:16116964 NCBI chr 1:9,868,355...9,972,795
Ensembl chr 1:9,868,332...9,971,070
JBrowse link
G Sh3glb1 SH3-domain GRB2-like B1 (endophilin) multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of SH3GLB1 mRNA CTD PMID:25905778 NCBI chr 3:144,389,426...144,426,186
Ensembl chr 3:144,389,439...144,426,096
JBrowse link
G Shc1 src homology 2 domain-containing transforming protein C1 multiple interactions
increases expression
EXP SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of SHC1 mRNA]; SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of SHC1 protein]
Streptozocin results in increased expression of SHC1 mRNA; Streptozocin results in increased expression of SHC1 protein
CTD PMID:21778425 NCBI chr 3:89,325,858...89,337,336
Ensembl chr 3:89,325,750...89,337,334
JBrowse link
G Sim2 single-minded family bHLH transcription factor 2 increases expression ISO Streptozocin results in increased expression of SIM2 protein CTD PMID:23333261 NCBI chr16:93,885,963...93,927,891
Ensembl chr16:93,885,790...93,927,891
JBrowse link
G Sirt1 sirtuin 1 decreases activity
multiple interactions
decreases expression
EXP
ISO
Streptozocin results in decreased activity of SIRT1 protein
[Dietary Fats co-treated with Streptozocin] results in decreased expression of SIRT1 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of SIRT1 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of SIRT1 protein; AICA ribonucleotide inhibits the reaction [Streptozocin results in decreased activity of SIRT1 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SIRT1 protein]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SIRT1 mRNA]; Plant Extracts inhibits the reaction [Streptozocin results in decreased expression of SIRT1 protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased activity of SIRT1 protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of SIRT1 protein]; SIRT1 protein inhibits the reaction [Streptozocin promotes the reaction [JUN protein binds to PARP1 protein]]; SIRT1 protein inhibits the reaction [Streptozocin promotes the reaction [PARP1 protein binds to MMP9 promoter]]; SIRT1 protein inhibits the reaction [Streptozocin promotes the reaction [RELA protein binds to PARP1 protein]]; SIRT1 protein inhibits the reaction [Streptozocin results in decreased expression of SOD2 protein]; SIRT1 protein inhibits the reaction [Streptozocin results in decreased expression of SOD2]; SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of CDKN1A]; SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of SERPINE1 mRNA]; SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of SERPINE1]; SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of SHC1 mRNA]; SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of SHC1 protein]; SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of TRP53]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SIRT1 mRNA]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SIRT1 protein]
[Streptozocin co-treated with bisphenol A] results in decreased expression of SIRT1 protein; [Streptozocin co-treated with Resveratrol co-treated with Ramipril] results in increased expression of SIRT1 protein; [Streptozocin co-treated with Resveratrol] results in increased expression of SIRT1 protein; Organoselenium Compounds inhibits the reaction [Streptozocin results in decreased expression of SIRT1 protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of SIRT1 mRNA]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of SIRT1 protein]; STUB1 inhibits the reaction [Streptozocin results in decreased expression of SIRT1 protein]
Streptozocin results in decreased expression of SIRT1 mRNA; Streptozocin results in decreased expression of SIRT1 protein
CTD PMID:21778425 PMID:22058332 PMID:22733486 PMID:22744176 PMID:23792339 More... NCBI chr10:63,154,784...63,174,814
Ensembl chr10:63,154,784...63,217,483
JBrowse link
G Slc10a2 solute carrier family 10, member 2 multiple interactions EXP [Dietary Fats co-treated with Streptozocin] results in increased expression of SLC10A2 mRNA CTD PMID:29382564 NCBI chr 8:5,133,219...5,155,287
Ensembl chr 8:5,133,219...5,155,351
JBrowse link
G Slc13a5 solute carrier family 13 (sodium-dependent citrate transporter), member 5 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of SLC13A5 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of SLC13A5 mRNA] CTD PMID:33484791 NCBI chr11:72,132,816...72,158,092
Ensembl chr11:72,132,815...72,158,048
JBrowse link
G Slc15a3 solute carrier family 15, member 3 multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of SLC15A3 mRNA CTD PMID:25905778 NCBI chr19:10,819,908...10,835,279
Ensembl chr19:10,817,091...10,836,726
JBrowse link
G Slc1a3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 multiple interactions
decreases expression
ISO Curcumin inhibits the reaction [Streptozocin results in decreased expression of SLC1A3 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in decreased expression of SLC1A3 mRNA]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of SLC1A3 mRNA]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of SLC1A3 protein]
Streptozocin results in decreased expression of SLC1A3 mRNA; Streptozocin results in decreased expression of SLC1A3 protein
CTD PMID:23267840 PMID:26677078 NCBI chr15:8,663,608...8,742,648
Ensembl chr15:8,663,608...8,740,248
JBrowse link
G Slc20a2 solute carrier family 20, member 2 multiple interactions
increases expression
EXP INS1 protein inhibits the reaction [Streptozocin results in increased expression of SLC20A2 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of SLC20A2 protein]
Streptozocin results in increased expression of SLC20A2 mRNA; Streptozocin results in increased expression of SLC20A2 protein
CTD PMID:29216956 NCBI chr 8:22,966,771...23,059,632
Ensembl chr 8:22,966,804...23,059,628
JBrowse link
G Slc22a1 solute carrier family 22 (organic cation transporter), member 1 decreases expression ISO Streptozocin results in decreased expression of SLC22A1 protein CTD PMID:19605544 NCBI chr17:12,867,761...12,894,725
Ensembl chr17:12,867,756...12,894,716
JBrowse link
G Slc22a2 solute carrier family 22 (organic cation transporter), member 2 decreases expression ISO Streptozocin results in decreased expression of SLC22A2 protein CTD PMID:19605544 NCBI chr17:12,803,076...12,847,376
Ensembl chr17:12,803,019...12,847,375
JBrowse link
G Slc22a29 solute carrier family 22. member 29 multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of SLC22A29 mRNA CTD PMID:33484791 NCBI chr19:8,137,532...8,230,739
Ensembl chr19:8,137,529...8,196,264
JBrowse link
G Slc22a6 solute carrier family 22 (organic anion transporter), member 6 multiple interactions
decreases expression
ISO Trientine inhibits the reaction [Streptozocin results in decreased expression of SLC22A6 protein] CTD PMID:19634143 NCBI chr19:8,595,360...8,605,663
Ensembl chr19:8,595,403...8,605,663
JBrowse link
G Slc25a1 solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1 multiple interactions
decreases expression
ISO cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SLC25A1 protein]; tin mesoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SLC25A1 protein]] CTD PMID:16595661 NCBI chr16:17,743,075...17,746,083
Ensembl chr16:17,743,087...17,746,083
JBrowse link
G Slc25a10 solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10 increases expression
multiple interactions
decreases expression
ISO Streptozocin results in increased expression of SLC25A10 protein
cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SLC25A10 protein]; tin mesoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SLC25A10 protein]]; Trientine inhibits the reaction [Streptozocin results in increased expression of SLC25A10 protein]
CTD PMID:16595661 PMID:19634143 NCBI chr11:120,382,663...120,391,987
Ensembl chr11:120,382,666...120,390,013
JBrowse link
G Slc25a19 solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19 multiple interactions
decreases expression
ISO HMOX1 protein inhibits the reaction [Streptozocin results in decreased expression of SLC25A19 protein]
cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SLC25A19 protein]; tin mesoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SLC25A19 protein]]
CTD PMID:16595661 NCBI chr11:115,504,991...115,519,122
Ensembl chr11:115,505,004...115,519,121
JBrowse link
G Slc25a20 solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20 decreases expression
multiple interactions
ISO Streptozocin results in decreased expression of SLC25A20 protein
cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SLC25A20 protein]; tin mesoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SLC25A20 protein]]
CTD PMID:16595661 NCBI chr 9:108,539,335...108,561,841
Ensembl chr 9:108,539,287...108,561,840
JBrowse link
G Slc25a26 solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 26 affects expression EXP Streptozocin affects the expression of SLC25A26 mRNA CTD PMID:18583417 NCBI chr 6:94,477,272...94,581,636
Ensembl chr 6:94,477,312...94,581,653
JBrowse link
G Slc25a3 solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3 increases expression
multiple interactions
ISO Streptozocin results in increased expression of SLC25A3 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of SLC25A3 protein]
CTD PMID:19634143 NCBI chr10:90,952,436...90,959,902
Ensembl chr10:90,952,436...90,959,921
JBrowse link
G Slc25a4 solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4 multiple interactions EXP SLC25A4 protein inhibits the reaction [Streptozocin results in increased expression of NPPA mRNA] CTD PMID:18945756 NCBI chr 8:46,660,205...46,664,099
Ensembl chr 8:46,659,834...46,664,321
JBrowse link
G Slc25a47 solute carrier family 25, member 47 affects expression EXP Streptozocin affects the expression of SLC25A47 mRNA CTD PMID:18583417 NCBI chr12:108,815,740...108,822,741
Ensembl chr12:108,801,972...108,822,741
JBrowse link
G Slc25a5 solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5 increases expression
multiple interactions
ISO Streptozocin results in increased expression of SLC25A5 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of SLC25A5 protein]
CTD PMID:19634143 NCBI chr  X:36,059,250...36,062,461
Ensembl chr  X:36,059,304...36,062,460
JBrowse link
G Slc27a1 solute carrier family 27 (fatty acid transporter), member 1 increases expression
multiple interactions
ISO Streptozocin results in increased expression of SLC27A1 mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of SLC27A1 mRNA]
CTD PMID:16684804 NCBI chr 8:72,021,372...72,039,951
Ensembl chr 8:72,021,526...72,039,946
JBrowse link
G Slc27a5 solute carrier family 27 (fatty acid transporter), member 5 multiple interactions EXP [Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC27A5 mRNA CTD PMID:29382564 NCBI chr 7:12,722,273...12,732,119
Ensembl chr 7:12,722,273...12,732,119
JBrowse link
G Slc2a1 solute carrier family 2 (facilitated glucose transporter), member 1 multiple interactions
increases expression
ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A1 protein; bicalutamide promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A1 protein]; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in increased expression of SLC2A1 mRNA] CTD PMID:16409969 PMID:35151640 NCBI chr 4:118,966,001...118,994,527
Ensembl chr 4:118,965,908...118,995,180
JBrowse link
G Slc2a2 solute carrier family 2 (facilitated glucose transporter), member 2 increases response to substance
decreases expression
multiple interactions
increases expression
ISO
EXP
SLC2A2 protein results in increased susceptibility to Streptozocin
Streptozocin results in decreased expression of SLC2A2 mRNA
5-thio-D-glucose inhibits the reaction [Streptozocin results in decreased expression of SLC2A2 mRNA]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A2 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A2 protein; Dibutyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A2 protein]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A2 mRNA]; L 783281 inhibits the reaction [Dibutyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A2 protein]]
[Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A2 mRNA; [Streptozocin co-treated with Cadmium] results in decreased expression of SLC2A2 protein; allyl isothiocyanate inhibits the reaction [Streptozocin promotes the reaction [Dietary Fats results in decreased expression of SLC2A2 protein]]; allyl methyl sulfide inhibits the reaction [Streptozocin results in decreased expression of SLC2A2 protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of SLC2A2 protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of SLC2A2 protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased expression of SLC2A2 protein]; myrtenal inhibits the reaction [Streptozocin results in decreased expression of SLC2A2 protein]; piperlongumine inhibits the reaction [Streptozocin results in decreased expression of SLC2A2 protein]; repaglinide analog affects the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A2 mRNA]; repaglinide inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A2 mRNA]; Streptozocin promotes the reaction [Dietary Fats results in decreased expression of SLC2A2 protein]; Zinc inhibits the reaction [Streptozocin results in increased expression of SLC2A2 protein]
CTD PMID:11151762 PMID:12137914 PMID:24923654 PMID:25541178 PMID:27417257 More... NCBI chr 3:28,752,052...28,782,510
Ensembl chr 3:28,752,052...28,785,508
JBrowse link
G Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4 affects expression
affects localization
decreases expression
multiple interactions
ISO
EXP
Streptozocin affects the expression of SLC2A4 protein
Streptozocin affects the localization of SLC2A4 protein
Streptozocin results in decreased expression of SLC2A4 mRNA; Streptozocin results in decreased expression of SLC2A4 protein
[Dietary Fats co-treated with Streptozocin co-treated with Quercetin] affects the expression of SLC2A4 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A4 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A4 protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A4 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A4 protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of SLC2A4 protein; asiatic acid inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]; Berberine inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A4 protein]; bis(maltolato)oxovanadium(IV) inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]; chebulagic acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A4 protein]; chromium mesoporphyrin inhibits the reaction [Hemin inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]]; cinnamaldehyde inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A4 protein]; cinnamaldehyde inhibits the reaction [Streptozocin affects the localization of SLC2A4 protein]; eupafolin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of SLC2A4 protein]; Ficusin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A4 mRNA]; GHRL protein promotes the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]; Hemin inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]; INS protein inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]; mangiferin inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]; mangiferin inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A4 protein]; myrtenal inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]; naloxonazine inhibits the reaction [Valsartan inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]]; naloxonazine inhibits the reaction [Valsartan inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]]; Naloxone inhibits the reaction [Tramadol inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]]; naringenin inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]; naringenin inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]; nerolidol inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A4 protein]; Pioglitazone inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A4 mRNA]; piperlongumine inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]; Plant Extracts inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A4 mRNA]; Plant Extracts inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A4 protein]; Plant Extracts inhibits the reaction [Streptozocin affects the localization of SLC2A4 protein]; plumbagin inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]; plumbagin inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]; Polysaccharides inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]; Polysaccharides inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of SLC2A4 protein]; Resveratrol inhibits the reaction [Streptozocin inhibits the reaction [CAV3 protein binds to SLC2A4 protein]]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]; Streptozocin inhibits the reaction [CAV3 protein binds to SLC2A4 protein]; Tramadol inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]; Tramadol inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]; Valsartan inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]; Valsartan inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]
[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A4 protein; [Streptozocin co-treated with bisphenol A] results in decreased expression of SLC2A4 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A4 protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A4 protein]; Metformin inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A4 protein]; Streptozocin inhibits the reaction [Ethinyl Estradiol results in increased expression of SLC2A4 mRNA]; Streptozocin inhibits the reaction [octylphenol results in increased expression of SLC2A4 mRNA]
CTD PMID:11723065 PMID:12083368 PMID:12658023 PMID:17068109 PMID:17199717 More... NCBI chr11:69,833,112...69,839,040
Ensembl chr11:69,833,365...69,839,014
JBrowse link
G Slc31a1 solute carrier family 31, member 1 decreases expression ISO Streptozocin results in decreased expression of SLC31A1 mRNA; Streptozocin results in decreased expression of SLC31A1 protein CTD PMID:24927960 NCBI chr 4:62,278,821...62,310,006
Ensembl chr 4:62,278,964...62,310,006
JBrowse link
G Slc31a2 solute carrier family 31, member 2 increases expression
multiple interactions
ISO Streptozocin results in increased expression of SLC31A2 mRNA; Streptozocin results in increased expression of SLC31A2 protein
Trientine promotes the reaction [Streptozocin results in increased expression of SLC31A2 mRNA]; Trientine promotes the reaction [Streptozocin results in increased expression of SLC31A2 protein]
CTD PMID:24927960 NCBI chr 4:62,198,630...62,216,649
Ensembl chr 4:62,180,799...62,216,648
JBrowse link
G Slc35b2 solute carrier family 35, member B2 multiple interactions
decreases expression
ISO cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SLC35B2 protein]; tin mesoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SLC35B2 protein]] CTD PMID:16595661 NCBI chr17:45,874,844...45,878,597
Ensembl chr17:45,874,800...45,878,597
JBrowse link
G Slc3a1 solute carrier family 3, member 1 decreases expression
multiple interactions
ISO Streptozocin results in decreased expression of SLC3A1 protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of SLC3A1 protein]
CTD PMID:19634143 NCBI chr17:85,335,775...85,371,669
Ensembl chr17:85,335,804...85,371,664
JBrowse link
G Slc51a solute carrier family 51, alpha subunit multiple interactions EXP [Dietary Fats co-treated with Streptozocin] results in increased expression of SLC51A mRNA CTD PMID:29382564 NCBI chr16:32,294,396...32,306,697
Ensembl chr16:32,293,322...32,306,697
JBrowse link
G Slc51b solute carrier family 51, beta subunit multiple interactions EXP [Dietary Fats co-treated with Streptozocin] results in increased expression of SLC51B mRNA CTD PMID:29382564 NCBI chr 9:65,320,035...65,330,055
Ensembl chr 9:65,319,996...65,330,237
JBrowse link
G Slc6a20a solute carrier family 6 (neurotransmitter transporter), member 20A multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of SLC6A20A mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of SLC6A20A mRNA] CTD PMID:33484791 NCBI chr 9:123,465,972...123,507,897
Ensembl chr 9:123,463,835...123,507,950
JBrowse link
G Slc6a4 solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased activity of SLC6A4 protein; [Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of SLC6A4 mRNA; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased activity of SLC6A4 protein]; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of SLC6A4 mRNA] CTD PMID:32303808 NCBI chr11:76,889,423...76,923,169
Ensembl chr11:76,889,429...76,923,166
JBrowse link
G Slc6a6 solute carrier family 6 (neurotransmitter transporter, taurine), member 6 multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of SLC6A6 mRNA CTD PMID:25905778 NCBI chr 6:91,661,031...91,736,044
Ensembl chr 6:91,661,034...91,736,047
JBrowse link
G Slc7a7 solute carrier family 7 (cationic amino acid transporter, y+ system), member 7 multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of SLC7A7 mRNA CTD PMID:25905778 NCBI chr14:54,606,899...54,657,525
Ensembl chr14:54,606,899...54,655,237
JBrowse link
G Slco1a1 solute carrier organic anion transporter family, member 1a1 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of SLCO1A1 mRNA CTD PMID:29127188 NCBI chr 6:141,853,007...141,892,688
Ensembl chr 6:141,853,008...141,892,688
JBrowse link
G Smad1 SMAD family member 1 increases expression ISO Streptozocin results in increased expression of SMAD1 CTD PMID:25617480 NCBI chr 8:80,065,024...80,126,057
Ensembl chr 8:80,065,024...80,126,147
JBrowse link
G Smad2 SMAD family member 2 increases phosphorylation
multiple interactions
ISO
EXP
Streptozocin results in increased phosphorylation of SMAD2 protein
[Streptozocin co-treated with Resveratrol co-treated with Ramipril] results in decreased phosphorylation of SMAD2 protein; Resveratrol inhibits the reaction [Streptozocin results in increased phosphorylation of SMAD2 protein]
[Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased phosphorylation of SMAD2 protein]; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased phosphorylation of SMAD2 protein
CTD PMID:21300041 PMID:31062909 PMID:38282657 NCBI chr18:76,369,898...76,444,819
Ensembl chr18:76,374,651...76,444,034
JBrowse link
G Smad3 SMAD family member 3 multiple interactions
increases phosphorylation
ISO
EXP
resveratrol inhibits the reaction [Streptozocin results in increased phosphorylation of SMAD3 protein]
[fatostatin co-treated with Streptozocin] results in increased phosphorylation of SMAD3 protein; [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased phosphorylation of SMAD3 protein]; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased phosphorylation of SMAD3 protein
CTD PMID:21300041 PMID:29420703 PMID:38282657 NCBI chr 9:63,554,048...63,665,276
Ensembl chr 9:63,554,049...63,665,276
JBrowse link
G Smad4 SMAD family member 4 multiple interactions
increases expression
decreases expression
ISO
EXP
Trientine inhibits the reaction [Streptozocin results in increased expression of SMAD4 mRNA]
Streptozocin results in increased expression of SMAD4 mRNA; Streptozocin results in increased expression of SMAD4 protein
SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of SMAD4 mRNA]
CTD PMID:16973718 PMID:18246672 PMID:27629361 NCBI chr18:73,767,861...73,836,862
Ensembl chr18:73,772,080...73,836,851
JBrowse link
G Smad6 SMAD family member 6 increases expression ISO Streptozocin results in increased expression of SMAD6 protein CTD PMID:17437042 NCBI chr 9:63,860,358...63,929,374
Ensembl chr 9:63,860,358...63,929,341
JBrowse link
G Smad7 SMAD family member 7 affects expression
decreases expression
ISO Streptozocin affects the expression of SMAD7 mRNA; Streptozocin affects the expression of SMAD7 protein
Streptozocin results in decreased expression of SMAD7 mRNA
CTD PMID:17437042 PMID:32959695 NCBI chr18:75,500,436...75,529,006
Ensembl chr18:75,500,600...75,529,006
JBrowse link
G Smpd1 sphingomyelin phosphodiesterase 1, acid lysosomal decreases response to substance EXP SMPD1 gene mutant form results in decreased susceptibility to Streptozocin CTD PMID:32481596 NCBI chr 7:105,203,567...105,207,596
Ensembl chr 7:105,203,567...105,207,596
JBrowse link
G Snap23 synaptosomal-associated protein 23 multiple interactions ISO [Streptozocin co-treated with Niacinamide] results in decreased expression of SNAP23 mRNA; resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of SNAP23 mRNA] CTD PMID:25999625 NCBI chr 2:120,398,137...120,436,829
Ensembl chr 2:120,398,152...120,431,736
JBrowse link
G Sncb synuclein, beta multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of SNCB mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of SNCB mRNA] CTD PMID:33484791 NCBI chr13:54,906,673...54,914,435
Ensembl chr13:54,906,673...54,914,408
JBrowse link
G Sncg synuclein, gamma increases expression
multiple interactions
ISO Streptozocin results in increased expression of SNCG mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of SNCG mRNA]
CTD PMID:16684804 NCBI chr14:34,092,231...34,096,626
Ensembl chr14:34,092,231...34,096,746
JBrowse link
G Snord15a small nucleolar RNA, C/D box 15A increases expression EXP Streptozocin results in increased expression of SNORD15A mRNA CTD PMID:27629361 NCBI chr 7:99,131,992...99,132,139
Ensembl chr 7:99,131,992...99,132,139
JBrowse link
G Snord49a small nucleolar RNA, C/D box 49A increases expression EXP Streptozocin results in increased expression of SNORD49A mRNA CTD PMID:27629361 NCBI chr11:62,494,286...62,494,347
Ensembl chr11:62,494,276...62,494,347
JBrowse link
G Snx12 sorting nexin 12 multiple interactions
decreases expression
ISO [Antagomirs results in decreased expression of MIR140 mRNA] inhibits the reaction [Streptozocin results in decreased expression of SNX12 protein]; Isoflurane promotes the reaction [Streptozocin results in decreased expression of SNX12 protein] CTD PMID:32062618 NCBI chr  X:100,132,973...100,266,185
Ensembl chr  X:100,141,392...100,266,169
JBrowse link
G Socs3 suppressor of cytokine signaling 3 decreases expression
multiple interactions
ISO Streptozocin results in decreased expression of SOCS3 protein
rosiglitazone inhibits the reaction [Streptozocin results in decreased expression of SOCS3 protein]
CTD PMID:21599458 NCBI chr11:117,856,905...117,860,192
Ensembl chr11:117,856,905...117,860,873
JBrowse link
G Sod1 superoxide dismutase 1, soluble increases expression
multiple interactions
decreases activity
affects expression
decreases expression
EXP
ISO
Streptozocin results in increased expression of SOD1 mRNA
[Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SOD1 protein]; [Resveratrol co-treated with Streptozocin] results in decreased expression of and results in decreased activity of SOD1 protein; [Resveratrol co-treated with Streptozocin] results in decreased expression of SOD1 mRNA; [Streptozocin co-treated with bisphenol A] results in decreased expression of SOD1 protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of SOD1 protein; [Streptozocin co-treated with Niacinamide] results in increased expression of SOD1 protein; allyl methyl sulfide inhibits the reaction [Streptozocin results in decreased activity of SOD1 protein]; arjunolic acid inhibits the reaction [Streptozocin results in decreased activity of SOD1 protein]; Dimethyl Fumarate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SOD1 protein]; Dronabinol promotes the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of SOD1 protein]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SOD1 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SOD1 protein]; nifuroxazide inhibits the reaction [Streptozocin results in decreased activity of SOD1 protein]; Plant Extracts inhibits the reaction [Streptozocin results in decreased expression of SOD1 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of SOD1 protein]; Streptozocin results in decreased expression of and results in decreased activity of SOD1 protein; Trientine inhibits the reaction [Streptozocin results in decreased expression of and results in decreased activity of SOD1 protein]; Trientine inhibits the reaction [Streptozocin results in decreased expression of SOD1 protein]
Streptozocin affects the expression of SOD1 mRNA
2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of SOD1 protein]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of SOD1 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of SOD1 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of SOD1 protein; [Streptozocin co-treated with Niacinamide] results in decreased activity of SOD1 protein; Berberine inhibits the reaction [Streptozocin affects the expression of SOD1 mRNA]; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SOD1 protein]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SOD1 mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of SOD1 protein]; Quercetin inhibits the reaction [Streptozocin results in decreased expression of SOD1 protein]; sulforaphane inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SOD1 mRNA]; sulforaphane inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SOD1 protein]
Streptozocin results in decreased expression of SOD1 mRNA; Streptozocin results in decreased expression of SOD1 protein
SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of CITED2 mRNA]; SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of ETS1 mRNA]; SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of MEF2C mRNA]; SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of MIR27A mRNA]; SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of MIR322 mRNA]; SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of SMAD4 mRNA]; SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of ZEB2 mRNA]; SOD1 protein inhibits the reaction [Streptozocin results in increased expression of MIR142 mRNA]; SOD1 protein inhibits the reaction [Streptozocin results in increased expression of MIR144 mRNA]; SOD1 protein inhibits the reaction [Streptozocin results in increased expression of MIR448 mRNA]
CTD PMID:15298345 PMID:18583417 PMID:19634143 PMID:20053369 PMID:20654064 More... NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217
JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial increases expression
multiple interactions
decreases response to substance
affects expression
decreases expression
decreases activity
EXP
ISO
Streptozocin results in increased expression of SOD2 mRNA
[Ascorbic Acid co-treated with Vitamin E co-treated with beta Carotene co-treated with Copper] inhibits the reaction [Streptozocin results in decreased expression of SOD2 mRNA]; [Ascorbic Acid co-treated with Vitamin E co-treated with beta Carotene co-treated with Copper] inhibits the reaction [Streptozocin results in decreased expression of SOD2 protein]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of SOD2 mRNA; [Streptozocin co-treated with Cholesterol, Dietary] results in decreased expression of SOD2 protein; arjunolic acid inhibits the reaction [Streptozocin results in decreased activity of SOD2 protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Cholesterol, Dietary] results in decreased expression of SOD2 protein]; idebenone inhibits the reaction [Streptozocin results in decreased expression of SOD2 protein]; INS protein promotes the reaction [Streptozocin results in decreased activity of SOD2 protein]; Plant Extracts inhibits the reaction [Streptozocin results in decreased expression of and results in decreased activity of SOD2 protein]; Streptozocin results in decreased expression of and results in decreased activity of SOD2 protein; STUB1 inhibits the reaction [Streptozocin results in decreased expression of SOD2 protein]; Thioctic Acid inhibits the reaction [Streptozocin results in decreased activity of SOD2 protein]; Trientine inhibits the reaction [Streptozocin results in decreased expression of SOD2 protein]
CAT protein promotes the reaction [SOD2 protein results in decreased susceptibility to Streptozocin]; SOD2 protein promotes the reaction [CAT protein results in decreased susceptibility to Streptozocin]
[Dietary Fats co-treated with Streptozocin] results in decreased expression of SOD2 mRNA; [Streptozocin co-treated with INS1 protein co-treated with Glutathione] affects the expression of SOD2 mRNA; Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of SOD2 protein]; Berberine inhibits the reaction [Streptozocin affects the expression of SOD2 mRNA]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SOD2 mRNA]; Physostigmine inhibits the reaction [Streptozocin results in decreased expression of SOD2 protein]; Quercetin inhibits the reaction [Streptozocin results in decreased expression of SOD2 protein]; SIRT1 protein inhibits the reaction [Streptozocin results in decreased expression of SOD2 protein]; SIRT1 protein inhibits the reaction [Streptozocin results in decreased expression of SOD2]; SOD2 protein inhibits the reaction [Streptozocin results in increased phosphorylation of MAPT protein]
Streptozocin results in decreased expression of SOD2; Streptozocin results in decreased expression of SOD2 protein
Streptozocin results in decreased expression of SOD2 mRNA; Streptozocin results in decreased expression of SOD2 protein
CTD PMID:14871415 PMID:15298345 PMID:15855331 PMID:18779489 PMID:19634143 More... NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950
JBrowse link
G Sod3 superoxide dismutase 3, extracellular multiple interactions
decreases expression
ISO
EXP
cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SOD3 protein]; tin mesoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SOD3 protein]]; Trientine inhibits the reaction [Streptozocin results in decreased expression of SOD3 mRNA]; Trientine inhibits the reaction [Streptozocin results in decreased expression of SOD3 protein]
Streptozocin results in decreased expression of SOD3 mRNA; Streptozocin results in decreased expression of SOD3 protein
[Streptozocin results in decreased activity of SOD3 protein] which results in increased chemical synthesis of Peroxynitrous Acid; [Streptozocin results in decreased activity of SOD3 protein] which results in increased chemical synthesis of Superoxides; Copper inhibits the reaction [Streptozocin results in decreased activity of SOD3 protein]; INS protein inhibits the reaction [Streptozocin results in decreased activity of SOD3 protein]; SOD3 gene mutant form promotes the reaction [Streptozocin results in increased chemical synthesis of Superoxides]; Streptozocin results in increased expression of and results in decreased activity of SOD3 protein
CTD PMID:15821039 PMID:16973718 PMID:23884884 NCBI chr 5:52,521,146...52,527,080
Ensembl chr 5:52,521,133...52,528,760
JBrowse link
G Sord sorbitol dehydrogenase multiple interactions
increases expression
increases glycation
ISO Streptozocin results in decreased expression of and results in decreased activity of SORD protein
Streptozocin results in increased expression of SORD mRNA
Streptozocin results in increased glycation of SORD protein
CTD PMID:8761460 NCBI chr 2:122,065,320...122,095,818
Ensembl chr 2:122,065,230...122,095,821
JBrowse link
G Sort1 sortilin 1 decreases expression EXP Streptozocin results in decreased expression of SORT1 protein CTD PMID:25805502 NCBI chr 3:108,191,272...108,268,835
Ensembl chr 3:108,191,398...108,268,827
JBrowse link
G Sox11 SRY (sex determining region Y)-box 11 decreases expression ISO Streptozocin results in decreased expression of SOX11 mRNA; Streptozocin results in decreased expression of SOX11 protein CTD PMID:32935389 NCBI chr12:27,384,267...27,392,717
Ensembl chr12:27,384,263...27,392,573
JBrowse link
G Spag9 sperm associated antigen 9 decreases expression ISO Streptozocin results in decreased expression of SPAG9 mRNA CTD PMID:25905778 NCBI chr11:93,886,794...94,016,919
Ensembl chr11:93,886,917...94,016,911
JBrowse link
G Sparc secreted acidic cysteine rich glycoprotein increases expression EXP Streptozocin results in increased expression of SPARC mRNA; Streptozocin results in increased expression of SPARC protein CTD PMID:12660331 NCBI chr11:55,284,985...55,310,906
Ensembl chr11:55,285,326...55,314,009
JBrowse link
G Sphk1 sphingosine kinase 1 increases expression EXP
ISO
Streptozocin results in increased expression of SPHK1
Streptozocin results in increased expression of SPHK1 mRNA; Streptozocin results in increased expression of SPHK1 protein
CTD PMID:19657322 PMID:21998146 NCBI chr11:116,421,662...116,427,502
Ensembl chr11:116,421,751...116,427,501
JBrowse link
G Spmip11 sperm microtubule inner protein 11 multiple interactions
increases secretion
decreases expression
ISO [Streptozocin co-treated with Fructose] results in decreased expression of NPHS1 mRNA; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in decreased expression of NPHS1 mRNA]; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in decreased expression of NPHS1 mRNA]; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in decreased expression of NPHS1 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in decreased expression of NPHS1 mRNA]; Mycophenolic Acid inhibits the reaction [Streptozocin results in decreased expression of NPHS1 mRNA]; Mycophenolic Acid inhibits the reaction [Streptozocin results in decreased expression of NPHS1 protein]; procyanidin B2 inhibits the reaction [Streptozocin results in increased expression of NPHS1 mRNA]; procyanidin B2 inhibits the reaction [Streptozocin results in increased expression of NPHS1 protein]; stannous mesoporphyrin inhibits the reaction [4-(4-(3-adamantan-1-ylureido)cyclohexyloxy)benzoic acid inhibits the reaction [Streptozocin results in increased secretion of NPHS1 protein]]; Valsartan inhibits the reaction [Streptozocin results in decreased expression of NPHS1 mRNA]; Valsartan inhibits the reaction [Streptozocin results in decreased expression of NPHS1 protein]
Streptozocin results in decreased expression of NPHS1 mRNA; Streptozocin results in decreased expression of NPHS1 protein
CTD PMID:17624267 PMID:20547220 PMID:23611540 PMID:25199697 PMID:30551545 NCBI chr15:98,468,885...98,487,469
Ensembl chr15:98,468,885...98,487,461
JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions
increases expression
ISO pioglitazone inhibits the reaction [Streptozocin results in increased expression of SPP1 mRNA]; pioglitazone inhibits the reaction [Streptozocin results in increased expression of SPP1 protein]; vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of SPP1 mRNA]
Streptozocin results in increased expression of SPP1 mRNA; Streptozocin results in increased expression of SPP1 protein
CTD PMID:16684804 PMID:16979161 PMID:16980342 NCBI chr 5:104,582,977...104,588,919
Ensembl chr 5:104,582,984...104,588,916
JBrowse link
G Sprr2a1 small proline-rich protein 2A1 multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of SPRR2A1 mRNA CTD PMID:33484791 NCBI chr 3:92,123,142...92,129,798
Ensembl chr 3:92,123,106...92,129,218
JBrowse link
G Sprr2a2 small proline-rich protein 2A2 multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of SPRR2A2 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of SPRR2A2 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of SPRR2A2 mRNA] CTD PMID:33484791 NCBI chr 3:92,157,982...92,164,610
Ensembl chr 3:92,123,227...92,164,031
JBrowse link
G Spsb4 splA/ryanodine receptor domain and SOCS box containing 4 multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of SPSB4 mRNA CTD PMID:25905778 NCBI chr 9:96,825,535...96,900,408
Ensembl chr 9:96,825,535...96,900,896
JBrowse link
G Sqstm1 sequestosome 1 multiple interactions
increases expression
EXP
ISO
bafilomycin A1 inhibits the reaction [Resveratrol inhibits the reaction [Streptozocin results in increased expression of SQSTM1 protein]]; HU 308 inhibits the reaction [Streptozocin results in increased expression of SQSTM1 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of SQSTM1 protein]; Streptozocin promotes the reaction [bafilomycin A1 results in increased expression of SQSTM1 protein]
[Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of SQSTM1 protein; [Dietary Fats co-treated with Streptozocin] results in increased expression of SQSTM1 protein
CTD PMID:24889822 PMID:30459625 PMID:35786680 NCBI chr11:50,090,979...50,105,303
Ensembl chr11:50,090,193...50,101,654
JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of SRD5A1 mRNA CTD PMID:29127188 NCBI chr13:69,721,568...69,759,611
Ensembl chr13:69,721,568...69,759,561
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions
increases expression
decreases expression
increases expression
ISO
EXP
[[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in decreased expression of SREBF1 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of SREBF1 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of SREBF1 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of SREBF1 protein; [Streptozocin co-treated with Cadmium] results in increased expression of SREBF1 protein; Allopurinol inhibits the reaction [Streptozocin results in increased expression of SREBF1 mRNA]; Allopurinol inhibits the reaction [Streptozocin results in increased expression of SREBF1 protein]; Fungal Polysaccharides inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SREBF1 mRNA]; Fungal Polysaccharides inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SREBF1 protein]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SREBF1 mRNA]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SREBF1 protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of SREBF1 protein]; Quercetin inhibits the reaction [Streptozocin results in increased expression of SREBF1 mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of SREBF1 protein]
Streptozocin results in increased expression of SREBF1 mRNA; Streptozocin results in increased expression of SREBF1 protein
Streptozocin results in decreased expression of SREBF1 protein
[Dietary Fats co-treated with Streptozocin] results in decreased expression of SREBF1 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of SREBF1 mRNA; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of SREBF1 mRNA; Acrylamide inhibits the reaction [Streptozocin results in increased expression of SREBF1 mRNA]; fatostatin inhibits the reaction [Streptozocin results in increased expression of SREBF1 protein]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SREBF1 mRNA]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SREBF1 mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SREBF1 mRNA]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of SREBF1 mRNA]
streptozocin increases expression of Srebf1 protein in liver
CTD
RGD
PMID:22031849 PMID:23647015 PMID:25240712 PMID:28822685 PMID:29420703 More... RGD:401850547 NCBI chr11:60,089,910...60,113,407
Ensembl chr11:60,089,915...60,113,407
JBrowse link
G Srebf2 sterol regulatory element binding factor 2 multiple interactions
increases expression
ISO
EXP
[[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in decreased expression of SREBF2 mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of SREBF2 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of SREBF2 mRNA; [Streptozocin co-treated with Cadmium] results in increased expression of SREBF2 protein; Allopurinol inhibits the reaction [Streptozocin results in increased expression of SREBF2 mRNA]; Allopurinol inhibits the reaction [Streptozocin results in increased expression of SREBF2 protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of SREBF2 protein]; Quercetin inhibits the reaction [Streptozocin results in increased expression of SREBF2 mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of SREBF2 protein]
Streptozocin results in increased expression of SREBF2 mRNA; Streptozocin results in increased expression of SREBF2 protein
Acrylamide inhibits the reaction [Streptozocin results in increased expression of SREBF2 mRNA]; fatostatin inhibits the reaction [Streptozocin results in increased expression of SREBF2 protein]
CTD PMID:23647015 PMID:25240712 PMID:29420703 PMID:34896238 PMID:35786680 NCBI chr15:82,031,455...82,089,580
Ensembl chr15:82,031,382...82,089,580
JBrowse link
G Srxn1 sulfiredoxin 1 homolog (S. cerevisiae) multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of SRXN1 mRNA; Omaveloxolone analog promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of SRXN1 mRNA]; Omaveloxolone promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of SRXN1 mRNA] CTD PMID:32410268 NCBI chr 2:151,946,738...151,953,296
Ensembl chr 2:151,947,436...151,953,296
JBrowse link
G St3gal5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 increases expression
multiple interactions
ISO Streptozocin results in increased expression of ST3GAL5 mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of ST3GAL5 mRNA]
CTD PMID:16684804 NCBI chr 6:72,074,555...72,131,555
Ensembl chr 6:72,074,576...72,131,555
JBrowse link
G Stac3 SH3 and cysteine rich domain 3 decreases expression ISO Streptozocin results in decreased expression of STAC3 mRNA CTD PMID:25905778 NCBI chr10:127,337,505...127,344,692
Ensembl chr10:127,337,555...127,344,692
JBrowse link
G Stag3 STAG3 cohesin complex component multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of STAG3 mRNA CTD PMID:33484791 NCBI chr 5:138,270,757...138,310,659
Ensembl chr 5:138,278,502...138,310,655
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions
increases expression
increases phosphorylation
decreases phosphorylation
ISO 7-hydroxycoumarin inhibits the reaction [Streptozocin results in increased expression of STAT3 mRNA]; 7-hydroxycoumarin inhibits the reaction [Streptozocin results in increased expression of STAT3 protein]; Acetylcysteine inhibits the reaction [Streptozocin results in decreased phosphorylation of STAT3 protein]; Allopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased phosphorylation of STAT3 protein]]; Enalapril inhibits the reaction [Streptozocin results in increased expression of STAT3 mRNA]; Enalapril inhibits the reaction [Streptozocin results in increased expression of STAT3 protein]; nifuroxazide inhibits the reaction [Streptozocin results in increased phosphorylation of STAT3 protein]; Phosphocreatine inhibits the reaction [Streptozocin results in increased phosphorylation of STAT3 protein]; Propofol promotes the reaction [Streptozocin results in decreased phosphorylation of STAT3 protein]; Rosiglitazone inhibits the reaction [Streptozocin results in increased phosphorylation of STAT3 protein]; Simvastatin inhibits the reaction [Streptozocin results in increased phosphorylation of STAT3 protein]
Streptozocin results in increased expression of STAT3 mRNA; Streptozocin results in increased expression of STAT3 protein
CTD PMID:19958114 PMID:20821229 PMID:21599458 PMID:21912612 PMID:24810525 More... NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366
JBrowse link
G Stub1 STIP1 homology and U-Box containing protein 1 multiple interactions ISO STUB1 inhibits the reaction [Streptozocin results in decreased expression of AKT1 protein]; STUB1 inhibits the reaction [Streptozocin results in decreased expression of and results in decreased phosphorylation of GSK3B protein]; STUB1 inhibits the reaction [Streptozocin results in decreased expression of and results in decreased phosphorylation of NFE2L2 protein]; STUB1 inhibits the reaction [Streptozocin results in decreased expression of and results in decreased phosphorylation of PRKAA1 protein]; STUB1 inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein]; STUB1 inhibits the reaction [Streptozocin results in decreased expression of PPARGC1A protein]; STUB1 inhibits the reaction [Streptozocin results in decreased expression of SIRT1 protein]; STUB1 inhibits the reaction [Streptozocin results in decreased expression of SOD2 protein]; STUB1 inhibits the reaction [Streptozocin results in increased phosphorylation of IL1B protein]; STUB1 inhibits the reaction [Streptozocin results in increased phosphorylation of RELA protein]; STUB1 inhibits the reaction [Streptozocin results in increased phosphorylation of TNFA protein] CTD PMID:35442559 NCBI chr17:26,049,608...26,051,893
Ensembl chr17:26,049,479...26,052,378
JBrowse link
G Stx4a syntaxin 4A (placental) multiple interactions ISO [Streptozocin co-treated with Niacinamide] results in decreased expression of STX4 mRNA; resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of STX4 mRNA] CTD PMID:25999625 NCBI chr 7:127,439,832...127,450,160
Ensembl chr 7:127,423,466...127,448,191
JBrowse link
G Sucla2 succinate-Coenzyme A ligase, ADP-forming, beta subunit affects expression EXP Streptozocin affects the expression of SUCLA2 mRNA CTD PMID:18583417 NCBI chr14:73,790,226...73,833,584
Ensembl chr14:73,762,759...73,833,582
JBrowse link
G Sult1c2 sulfotransferase family, cytosolic, 1C, member 2 multiple interactions ISO [Resveratrol co-treated with Streptozocin] results in decreased expression of SULT1C2 mRNA CTD PMID:25905778 NCBI chr17:54,136,665...54,152,986
Ensembl chr17:54,136,665...54,153,367
JBrowse link
G Sult2a1 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 multiple interactions EXP [Dietary Fats co-treated with Streptozocin] results in increased expression of SULT2A1 mRNA CTD PMID:29382564 NCBI chr 7:13,530,171...13,571,335
Ensembl chr 7:13,530,171...13,571,334
JBrowse link
G Sult2a3 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 3 multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of SULT2A3 mRNA CTD PMID:33484791 NCBI chr 7:13,801,480...13,856,973
Ensembl chr 7:13,801,371...13,856,969
JBrowse link
G Syp synaptophysin increases expression
multiple interactions
decreases expression
EXP
ISO
Streptozocin results in increased expression of SYP mRNA
Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of SYP protein]; Physostigmine inhibits the reaction [Streptozocin results in decreased expression of SYP protein]; telmisartan inhibits the reaction [Streptozocin results in decreased expression of SYP protein]; Valsartan inhibits the reaction [Streptozocin results in decreased expression of SYP protein]
Streptozocin results in decreased expression of SYP mRNA; Streptozocin results in decreased expression of SYP protein
fasudil inhibits the reaction [Streptozocin results in decreased expression of SYP mRNA]; fasudil inhibits the reaction [Streptozocin results in decreased expression of SYP protein]; Vitamin B 12 inhibits the reaction [Streptozocin results in decreased expression of SYP protein]
CTD PMID:18487452 PMID:22062134 PMID:28499986 PMID:38049026 NCBI chr  X:7,504,819...7,519,495
Ensembl chr  X:7,504,710...7,519,495
JBrowse link
G Syvn1 synovial apoptosis inhibitor 1, synoviolin decreases expression
multiple interactions
ISO Streptozocin results in decreased expression of SYVN1 protein
4-phenylbutyric acid inhibits the reaction [Streptozocin results in decreased expression of SYVN1 protein]
CTD PMID:30980806 NCBI chr19:6,096,586...6,103,748
Ensembl chr19:6,096,606...6,103,742
JBrowse link
G Tac1 tachykinin 1 multiple interactions
decreases expression
increases expression
decreases secretion
ISO Botulinum Toxins, Type A inhibits the reaction [Streptozocin results in decreased expression of TAC1 protein]; Butylated Hydroxytoluene inhibits the reaction [Streptozocin results in increased expression of TAC1 mRNA]; capsazepine inhibits the reaction [Streptozocin results in decreased expression of TAC1 protein]; imirestat inhibits the reaction [Streptozocin results in decreased expression of TAC1 protein]; RN 1734 inhibits the reaction [Streptozocin results in decreased expression of TAC1 protein]; sorbinil inhibits the reaction [Streptozocin results in increased expression of TAC1 mRNA]; Streptozocin promotes the reaction [KNG1 protein modified form results in increased secretion of TAC1 protein modified form]; U 0126 inhibits the reaction [Streptozocin results in decreased expression of TAC1 protein]
Streptozocin results in decreased secretion of TAC1 protein modified form
CTD PMID:1374869 PMID:9748608 PMID:20832942 PMID:30583000 NCBI chr 6:7,555,061...7,562,978
Ensembl chr 6:7,554,879...7,565,834
JBrowse link
G Tbc1d4 TBC1 domain family, member 4 multiple interactions EXP [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of and results in decreased phosphorylation of TBC1D4 protein; Metformin inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of TBC1D4 protein]; perilla seed oil inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of TBC1D4 protein] CTD PMID:31743741 NCBI chr14:101,679,800...101,846,717
Ensembl chr14:101,679,796...101,846,627
JBrowse link
G Tedc1 tubulin epsilon and delta complex 1 multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of TEDC1 mRNA CTD PMID:33484791 NCBI chr12:113,118,639...113,135,102
Ensembl chr12:113,120,041...113,129,668
JBrowse link
G Tek TEK receptor tyrosine kinase multiple interactions
increases expression
decreases expression
ISO baicalin inhibits the reaction [Streptozocin results in decreased expression of TEK mRNA]; Enalapril inhibits the reaction [Streptozocin results in increased expression of TEK mRNA]; Simvastatin inhibits the reaction [Streptozocin results in increased expression of TEK mRNA]
Streptozocin results in increased expression of TEK mRNA; Streptozocin results in increased expression of TEK protein
CTD PMID:15643138 PMID:19958114 PMID:20821229 PMID:34414639 NCBI chr 4:94,627,322...94,763,213
Ensembl chr 4:94,627,526...94,763,213
JBrowse link
G Tert telomerase reverse transcriptase multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of TERT protein; TERT protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARGC1A protein]; TERT protein inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARA mRNA]; TERT protein inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARG mRNA]; TERT protein inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARGC1A mRNA]; TERT protein inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of TFAM mRNA] CTD PMID:39265716 NCBI chr13:73,775,030...73,797,962
Ensembl chr13:73,775,030...73,797,962
JBrowse link
G Tfam transcription factor A, mitochondrial multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of TFAM mRNA; TERT protein inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of TFAM mRNA]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of TFAM mRNA] CTD PMID:37337224 PMID:39265716 NCBI chr10:71,061,298...71,074,157
Ensembl chr10:71,061,294...71,074,110
JBrowse link
G Tfap2a transcription factor AP-2, alpha multiple interactions ISO
EXP
MFN2 protein mutant form inhibits the reaction [Streptozocin promotes the reaction [TFAP2A protein binds to COL4A1 promoter]]; Streptozocin promotes the reaction [TFAP2A protein binds to COL4A1 promoter]
[Streptozocin co-treated with Raloxifene Hydrochloride] results in increased expression of TFAP2A protein
CTD PMID:23471663 PMID:27997345 NCBI chr13:40,867,278...40,891,715
Ensembl chr13:40,868,778...40,891,852
JBrowse link
G Tfrc transferrin receptor multiple interactions
increases expression
ISO iron pentacarbonyl inhibits the reaction [Streptozocin results in increased expression of TFRC mRNA] CTD PMID:22170771 NCBI chr16:32,427,714...32,451,612
Ensembl chr16:32,427,738...32,451,612
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression
multiple interactions
increases secretion
decreases methylation
decreases expression
decreases secretion
EXP
ISO
Streptozocin results in increased expression of TGFB1 mRNA; Streptozocin results in increased expression of TGFB1 protein
2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of TGFB1 mRNA]; 2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of TGFB1 protein]; 3-((6-(2-methoxyphenyl)pyrimidin-4-yl)amino)phenyl)methane sulfonamide inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; [Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein; [fatostatin co-treated with Streptozocin] results in increased expression of TGFB1 mRNA; [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of TGFB1 protein]; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of TGFB1 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of TGFB1 protein; [Streptozocin co-treated with Niacinamide] results in increased expression of TGFB1 mRNA; [Streptozocin co-treated with Niacinamide] results in increased expression of TGFB1 protein; bisphenol A inhibits the reaction [Streptozocin results in decreased secretion of TGFB1 protein]; CEBPB protein affects the reaction [Streptozocin results in increased expression of TGFB1 protein]; Chlorpyrifos inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; Curcumin analog inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 mRNA]; KLF15 gene mutant form inhibits the reaction [CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein]]; KLF15 gene mutant form promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of TGFB1 mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of TGFB1 protein]; Rosuvastatin Calcium inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of TGFB1 mRNA]; sarpogrelate inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein]; sulforaphane inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein]; sulforaphane inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; Telmisartan inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; Valsartan inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]
Streptozocin results in increased secretion of TGFB1 protein
1-hexacosanol inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein]; 7-hydroxycoumarin inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; 7-hydroxycoumarin inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein; [Streptozocin co-treated with Cadmium] results in increased expression of TGFB1 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein; [Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of TGFB1 protein; [Streptozocin co-treated with Ramipril] results in increased expression of TGFB1 protein; [Streptozocin co-treated with Resveratrol co-treated with Ramipril] results in increased expression of TGFB1 protein; [Streptozocin co-treated with Resveratrol] results in increased expression of TGFB1 protein; ACE2 inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; Aspirin inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; baicalin inhibits the reaction [Streptozocin results in decreased expression of TGFB1 mRNA]; benazepril inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; benazepril inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; bisphenol A diglycidyl ether inhibits the reaction [Calcitriol inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]]; bisphenol A diglycidyl ether inhibits the reaction [Calcitriol inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]]; Calcitriol inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; Calcitriol inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; crocin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein]; crocin inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; crocin promotes the reaction [Quercetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein]]; danggui buxue decoction inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of TGFB1 protein]; dapagliflozin inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; dapagliflozin promotes the reaction [Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of TGFB1 protein]]; Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein]; Enalapril inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; Enalapril inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; esculetin inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; fasudil inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; fenugreek seed meal inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; fenugreek seed meal inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; Flavonoids inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; Gallic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein]; Gallic Acid inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; hesperetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein]; mangiferin inhibits the reaction [Streptozocin results in increased secretion of TGFB1 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of TGFB1 protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of TGFB1 protein]; nifuroxazide inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; Plant Extracts inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein]; Pyridoxamine inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; Quercetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein]; Quercetin promotes the reaction [crocin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein]]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; sulbutiamine inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; Thioctic Acid inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; Trientine inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; Tropisetron inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; Vitamin E inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; XLF-III-43 inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; Zinc inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; zingerone inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]
Streptozocin results in increased expression of TGFB1; Streptozocin results in increased expression of TGFB1 mRNA; Streptozocin results in increased expression of TGFB1 protein
[ALPK1 protein results in increased susceptibility to Streptozocin] which results in increased expression of TGFB1 mRNA; [ALPK1 protein results in increased susceptibility to Streptozocin] which results in increased expression of TGFB1 protein
Streptozocin results in decreased methylation of TGFB1 promoter
CTD PMID:11798641 PMID:12660331 PMID:14586741 PMID:15309289 PMID:16409969 More... NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor I multiple interactions
increases expression
affects expression
ISO
EXP
benazepril inhibits the reaction [Streptozocin results in increased expression of TGFBR1 mRNA]; benazepril inhibits the reaction [Streptozocin results in increased expression of TGFBR1 protein]
Streptozocin results in increased expression of TGFBR1 mRNA; Streptozocin results in increased expression of TGFBR1 protein
Streptozocin affects the expression of TGFBR1 mRNA
fatostatin inhibits the reaction [Streptozocin results in increased expression of TGFBR1 mRNA]
CTD PMID:11798618 PMID:26073000 PMID:29420703 NCBI chr 4:47,353,258...47,414,926
Ensembl chr 4:47,353,222...47,414,931
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor II decreases expression EXP Streptozocin results in decreased expression of TGFBR2 protein CTD PMID:15496156 NCBI chr 9:115,916,763...116,004,431
Ensembl chr 9:115,913,361...116,004,428
JBrowse link
G Tgfbr3 transforming growth factor, beta receptor III multiple interactions ISO [Streptozocin co-treated with Resveratrol co-treated with Ramipril] results in decreased expression of TGFBR3 protein CTD PMID:31062909 NCBI chr 5:107,254,433...107,437,495
Ensembl chr 5:107,254,436...107,437,495
JBrowse link
G Th tyrosine hydroxylase multiple interactions
decreases expression
ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of TH protein; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TH protein]; Vitamin B 12 inhibits the reaction [Streptozocin results in decreased expression of TH protein] CTD PMID:35085591 PMID:38049026 NCBI chr 7:142,446,516...142,453,732
Ensembl chr 7:142,446,489...142,484,865
JBrowse link
G Thbd thrombomodulin multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of THBD mRNA CTD PMID:25905778 NCBI chr 2:148,246,391...148,250,108
Ensembl chr 2:148,246,386...148,250,108
JBrowse link
G Thbs1 thrombospondin 1 multiple interactions
increases expression
ISO pioglitazone inhibits the reaction [Streptozocin results in increased expression of THBS1 mRNA]; pioglitazone inhibits the reaction [Streptozocin results in increased expression of THBS1 protein]
Streptozocin results in increased expression of THBS1 mRNA; Streptozocin results in increased expression of THBS1 protein
CTD PMID:17063547 PMID:17117553 NCBI chr 2:117,942,357...117,957,614
Ensembl chr 2:117,942,357...117,957,614
JBrowse link
G Thbs2 thrombospondin 2 increases expression EXP Streptozocin results in increased expression of THBS2 protein CTD PMID:23723366 NCBI chr17:14,885,762...14,914,524
Ensembl chr17:14,885,762...14,914,497
JBrowse link
G Thbs4 thrombospondin 4 multiple interactions
increases expression
ISO vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of THBS4 mRNA] CTD PMID:16684804 NCBI chr13:92,888,094...92,931,326
Ensembl chr13:92,888,098...92,931,326
JBrowse link
G Thrsp thyroid hormone responsive multiple interactions
decreases expression
ISO
EXP
Fructose inhibits the reaction [Streptozocin results in decreased expression of THRSP mRNA]
[Streptozocin co-treated with Dietary Fats] results in decreased expression of THRSP mRNA
CTD PMID:2177838 PMID:29127188 NCBI chr 7:97,062,140...97,066,757
Ensembl chr 7:97,062,145...97,066,937
JBrowse link
G Timm8b translocase of inner mitochondrial membrane 8B affects expression EXP Streptozocin affects the expression of TIMM8B mRNA CTD PMID:18583417 NCBI chr 9:50,515,227...50,516,620
Ensembl chr 9:50,515,210...50,516,620
JBrowse link
G Timp1 tissue inhibitor of metalloproteinase 1 increases expression
multiple interactions
increases activity
decreases expression
ISO Streptozocin results in increased expression of TIMP1 mRNA
[Resveratrol co-treated with Streptozocin] results in increased expression of TIMP1 mRNA; Olive Oil promotes the reaction [Streptozocin results in increased activity of TIMP1 protein]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of TIMP1 mRNA]
CTD PMID:18246672 PMID:25246140 PMID:25905778 PMID:32662907 NCBI chr  X:20,736,524...20,740,972
Ensembl chr  X:20,736,405...20,740,974
JBrowse link
G Timp2 tissue inhibitor of metalloproteinase 2 increases expression
multiple interactions
increases activity
increases secretion
ISO
EXP
Streptozocin results in increased expression of TIMP2 mRNA; Streptozocin results in increased expression of TIMP2 protein
benazepril inhibits the reaction [Streptozocin results in increased expression of TIMP2 mRNA]; benazepril inhibits the reaction [Streptozocin results in increased expression of TIMP2 protein]; Olive Oil promotes the reaction [Streptozocin results in increased activity of TIMP2 protein]
Streptozocin results in increased secretion of TIMP2 protein
Raloxifene Hydrochloride inhibits the reaction [Streptozocin results in increased expression of TIMP2 mRNA]; Raloxifene Hydrochloride inhibits the reaction [Streptozocin results in increased secretion of TIMP2 protein]
CTD PMID:16732983 PMID:20821936 PMID:23471663 PMID:25246140 NCBI chr11:118,191,887...118,246,237
Ensembl chr11:118,191,887...118,246,566
JBrowse link
G Tinag tubulointerstitial nephritis antigen increases expression
multiple interactions
ISO Streptozocin results in increased expression of TINAG protein
Trientine inhibits the reaction [Streptozocin results in increased expression of TINAG protein]
CTD PMID:19634143 NCBI chr 9:76,858,980...76,953,084
Ensembl chr 9:76,858,975...76,953,076
JBrowse link
G Tjp1 tight junction protein 1 multiple interactions
decreases expression
EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of TJP1 protein; NLRP3 protein promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of TJP1 protein]; rhodioloside inhibits the reaction [Streptozocin results in decreased expression of TJP1 protein] CTD PMID:27783111 PMID:31682803 NCBI chr 7:64,945,913...65,177,629
Ensembl chr 7:64,945,913...65,177,529
JBrowse link
G Tjp2 tight junction protein 2 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of TJP2 protein; NLRP3 protein promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of TJP2 protein] CTD PMID:27783111 NCBI chr19:24,071,860...24,202,492
Ensembl chr19:24,071,869...24,202,394
JBrowse link
G Tkt transketolase multiple interactions ISO [benphothiamine co-treated with Streptozocin] results in increased activity of TKT protein CTD PMID:12592403 NCBI chr14:30,271,088...30,296,681
Ensembl chr14:30,270,316...30,296,677
JBrowse link
G Tlr3 toll-like receptor 3 multiple interactions
increases expression
ISO
EXP
TNF protein inhibits the reaction [Streptozocin results in increased expression of TLR3 mRNA] CTD PMID:20446767 NCBI chr 8:45,848,702...45,864,112
Ensembl chr 8:45,848,702...45,864,117
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions
increases expression
ISO
EXP
TNF protein inhibits the reaction [Streptozocin results in increased expression of TLR4 mRNA]
[Dietary Fats co-treated with Streptozocin] results in increased expression of TLR4 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of TLR4 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of TLR4 protein; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TLR4 mRNA]; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TLR4 protein]; esculetin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TLR4 mRNA]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TLR4 mRNA]
Streptozocin results in increased expression of TLR4 mRNA; Streptozocin results in increased expression of TLR4 protein
crocin inhibits the reaction [Streptozocin results in increased expression of TLR4 protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of TLR4 protein]; myrtenol inhibits the reaction [Streptozocin results in increased expression of TLR4 mRNA]; sulbutiamine inhibits the reaction [Streptozocin results in increased expression of TLR4 protein]; Tropisetron inhibits the reaction [Streptozocin results in increased expression of TLR4 protein]
CTD PMID:20446767 PMID:27769711 PMID:29409856 PMID:34477272 PMID:34610774 More... NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521
JBrowse link
G Tmed3 transmembrane p24 trafficking protein 3 multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of TMED3 mRNA CTD PMID:25905778 NCBI chr 9:89,581,256...89,587,096
Ensembl chr 9:89,581,259...89,587,121
JBrowse link
G Tmem181c-ps transmembrane protein 181C, pseudogene multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of TMEM181C-PS mRNA CTD PMID:33484791 NCBI chr17:6,877,502...6,888,324
Ensembl chr17:6,881,152...6,907,189
JBrowse link
G Tmsb10 thymosin beta 10 multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of TMSB10 mRNA CTD PMID:25905778 NCBI chr 6:72,934,330...72,935,731
Ensembl chr 6:72,934,330...72,935,731
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
increases secretion
decreases expression
ISO
EXP
PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; TNF protein inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]; TNF protein inhibits the reaction [Streptozocin results in increased expression of TLR3 mRNA]; TNF protein inhibits the reaction [Streptozocin results in increased expression of TLR4 mRNA]; TNF protein inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; TNF protein inhibits the reaction [Streptozocin results in increased expression of TNFRSF1B mRNA]
2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of TNF mRNA]; 2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of TNF protein]; 3-((6-(2-methoxyphenyl)pyrimidin-4-yl)amino)phenyl)methane sulfonamide inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; [Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of TNF protein; [Dietary Fats co-treated with Streptozocin] results in increased expression of TNF mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of TNF protein; [Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of TNF mRNA; [Streptozocin co-treated with bisphenol A] results in increased expression of TNF mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of TNF mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of TNF mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein; [Streptozocin co-treated with Dietary Fats] results in increased secretion of TNF protein; [Streptozocin co-treated with Niacinamide] results in increased expression of TNF mRNA; [Streptozocin co-treated with Niacinamide] results in increased expression of TNF protein; [Streptozocin co-treated with octylphenol] results in increased expression of TNF mRNA; [Streptozocin co-treated with Particulate Matter] results in increased expression of TNF protein; [Streptozocin co-treated with Vehicle Emissions] results in increased expression of TNF protein; Acrylamide inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; Alendronate inhibits the reaction [Streptozocin results in increased expression of TNF protein]; AM6545 inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; AM6545 inhibits the reaction [Streptozocin results in increased expression of TNF protein]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in increased expression of TNF protein]]; Ascorbic Acid inhibits the reaction [Streptozocin results in increased expression of TNF protein]; asiatic acid inhibits the reaction [Streptozocin results in increased expression of TNF protein]; asiatic acid promotes the reaction [Carnosine inhibits the reaction [Streptozocin results in increased expression of TNF protein]]; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased secretion of TNF protein]; Carnosine inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Carnosine promotes the reaction [asiatic acid inhibits the reaction [Streptozocin results in increased expression of TNF protein]]; Curcumin analog inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; Donepezil inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Dronabinol inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; esculetin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TNF mRNA]; esculetin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TNF protein]; etiron promotes the reaction [Streptozocin results in increased expression of TNF protein]; Genistein inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of TNF protein]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TNF mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of TNF mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of TNF protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of TNF protein]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; montelukast inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Perindopril inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; Perindopril inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in increased expression of TNF protein]]; salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the expression of TNF mRNA]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF mRNA]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein]; Sodium Selenite inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; sulforaphane inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein]
Streptozocin results in increased expression of TNF mRNA; Streptozocin results in increased expression of TNF protein
Streptozocin results in increased secretion of TNF protein
Streptozocin results in decreased expression of TNF protein
3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; 4-methyl-2-((2-methylbenzyl) amino)-1,3-thiazole-5-carboxylic acid inhibits the reaction [Streptozocin results in increased expression of TNF protein]; 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TNF protein]; 7-hydroxycoumarin inhibits the reaction [Streptozocin results in increased expression of TNF protein]; [Dietary Fats co-treated with Streptozocin co-treated with Quercetin] affects the expression of TNF mRNA; [Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in increased expression of TNF protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of TNF mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of TNF protein; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of TNF protein; [Niacinamide co-treated with Streptozocin] results in increased expression of TNF protein; [pimagedine co-treated with Fatty Acids, Omega-3] inhibits the reaction [Streptozocin results in increased expression of and results in increased secretion of TNF protein]; [Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein; [Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of TNF protein; [Streptozocin co-treated with Fructose] results in increased expression of TNF protein; [Streptozocin co-treated with Niacinamide] results in increased expression of TNF protein; [Streptozocin co-treated with Sodium Glutamate] results in increased expression of TNF protein; [Telmisartan co-treated with Aspirin] inhibits the reaction [Streptozocin results in increased expression of TNF protein]; [Vanadium co-treated with Selenium co-treated with Vitamin E co-treated with Chromium] inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Acetates inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [Streptozocin results in increased expression of TNF protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Aspirin inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Atorvastatin inhibits the reaction [Streptozocin results in increased expression of TNF protein]; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of TNF protein]; caffeic acid phenethyl ester inhibits the reaction [Streptozocin results in increased expression of TNF protein]; caryophyllene inhibits the reaction [Streptozocin results in increased expression of TNF protein]; chromium nicotinic acid complex inhibits the reaction [Streptozocin results in increased secretion of TNF protein]; cloricromen inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of TNF protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of TNF protein]; dapagliflozin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TNF protein]; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of TNF protein]; dapagliflozin promotes the reaction [Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of TNF protein]]; Diosgenin inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; Diosgenin inhibits the reaction [Streptozocin results in increased expression of TNF protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein]; Enalapril inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; Fungal Polysaccharides inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TNF mRNA]; Fungal Polysaccharides inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TNF protein]; Gallic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein]; Gliclazide inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in increased expression of TNF protein]; Gliclazide inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of TNF protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; Glyburide inhibits the reaction [Streptozocin results in increased expression of TNF protein]; hesperetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein]; Ibuprofen inhibits the reaction [Streptozocin results in increased expression of TNF protein]; IGF2R protein modified form promotes the reaction [Streptozocin results in increased expression of TNF protein]; Insulin promotes the reaction [Ozone inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of TNF protein]; mangiferin inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Melatonin inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Memantine inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of TNF protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; Metformin inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in increased expression of TNF protein]]; morin analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein]; myrtenol inhibits the reaction [Streptozocin results in increased expression of TNF protein]; nifuroxazide inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; Ozone inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; Pentoxifylline inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; Phycocyanin inhibits the reaction [Streptozocin results in increased expression of TNF protein]; picolinic acid inhibits the reaction [Streptozocin results in increased secretion of TNF protein]; pinitol inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of TNF protein]; piperlongumine inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; piperlongumine inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Plant Extracts inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein]; Pyridoxamine inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein]; Resveratrol inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in increased expression of TNF protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of TNF protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of TNF protein]; rhapontin inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; Rivastigmine inhibits the reaction [Streptozocin results in increased expression of TNF protein]; SMe1EC2 promotes the reaction [Streptozocin results in increased expression of TNF protein]; sodium arsenate promotes the reaction [Streptozocin results in increased expression of TNF protein]; Streptozocin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of TNF mRNA]; Streptozocin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of TNF protein]; Streptozocin results in increased expression of and results in increased secretion of TNF protein; sulbutiamine inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Thioctic Acid inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Tropisetron inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Wortmannin inhibits the reaction [Phycocyanin inhibits the reaction [Streptozocin results in increased expression of TNF protein]]; Zinc Compounds inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein]; Zinc inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]
CTD PMID:11357882 PMID:12123627 PMID:15309289 PMID:15862027 PMID:15892581 More... NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tnfaip1 tumor necrosis factor, alpha-induced protein 1 (endothelial) multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of TNFAIP1 mRNA CTD PMID:20665664 NCBI chr11:78,413,676...78,427,122
Ensembl chr11:78,413,676...78,427,158
JBrowse link
G Tnfrsf11b tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) decreases expression ISO Streptozocin results in decreased expression of TNFRSF11B mRNA CTD PMID:25617479 NCBI chr15:54,114,014...54,141,700
Ensembl chr15:54,114,015...54,141,880
JBrowse link
G Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b multiple interactions
increases expression
ISO
EXP
TNF protein inhibits the reaction [Streptozocin results in increased expression of TNFRSF1B mRNA] CTD PMID:20446767 NCBI chr 4:144,938,938...144,973,453
Ensembl chr 4:144,940,033...144,973,440
JBrowse link
G Tnfrsf8 tumor necrosis factor receptor superfamily, member 8 multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of TNFRSF8 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of TNFRSF8 mRNA; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNFRSF8 mRNA] CTD PMID:33484791 NCBI chr 4:144,993,702...145,041,734
Ensembl chr 4:144,993,707...145,041,734
JBrowse link
G Tnfrsf9 tumor necrosis factor receptor superfamily, member 9 multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of TNFRSF9 mRNA CTD PMID:33484791 NCBI chr 4:151,004,612...151,030,561
Ensembl chr 4:150,999,019...151,030,559
JBrowse link
G Tomm40 translocase of outer mitochondrial membrane 40 affects expression EXP Streptozocin affects the expression of TOMM40 mRNA CTD PMID:18583417 NCBI chr 7:19,435,238...19,449,370
Ensembl chr 7:19,435,238...19,449,363
JBrowse link
G Tph2 tryptophan hydroxylase 2 multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of TPH2 mRNA; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of TPH2 mRNA] CTD PMID:32303808 NCBI chr10:114,914,546...115,020,927
Ensembl chr10:114,914,546...115,020,927
JBrowse link
G Traf6 TNF receptor-associated factor 6 multiple interactions
increases expression
ISO
EXP
Glyburide inhibits the reaction [Streptozocin results in increased expression of TRAF6 protein]; Tropisetron inhibits the reaction [Streptozocin results in increased expression of TRAF6 protein]
[Streptozocin co-treated with Dietary Fats] results in increased expression of TRAF6 mRNA; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TRAF6 mRNA]
CTD PMID:36504472 PMID:37482253 NCBI chr 2:101,508,765...101,532,013
Ensembl chr 2:101,508,774...101,532,014
JBrowse link
G Trat1 T cell receptor associated transmembrane adaptor 1 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of TRAT1 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TRAT1 mRNA] CTD PMID:33484791 NCBI chr16:48,551,137...48,630,883
Ensembl chr16:48,551,137...48,592,384
JBrowse link
G Treh trehalase (brush-border membrane glycoprotein) multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of TREH mRNA CTD PMID:29127188 NCBI chr 9:44,584,530...44,597,602
Ensembl chr 9:44,584,530...44,597,602
JBrowse link
G Trh thyrotropin releasing hormone decreases expression
multiple interactions
ISO Streptozocin results in decreased expression of TRH mRNA
TRH protein inhibits the reaction [Streptozocin inhibits the reaction [Blood Glucose results in increased secretion of INS1 protein]]
CTD PMID:16118471 NCBI chr 6:92,219,042...92,221,631
Ensembl chr 6:92,219,042...92,221,631
JBrowse link
G Trib3 tribbles pseudokinase 3 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of TRIB3 mRNA CTD PMID:29127188 NCBI chr 2:152,179,345...152,185,980
Ensembl chr 2:152,179,342...152,185,952
JBrowse link
G Trp53 transformation related protein 53 multiple interactions
increases expression
EXP
ISO
2-amino-6-boronohexanoic acid inhibits the reaction [Streptozocin results in increased expression of TRP53 mRNA]; [Dietary Fats co-treated with Streptozocin] results in increased expression of TRP53 protein; IGF1 protein inhibits the reaction [Streptozocin results in increased expression of TRP53 protein]; NTN1 protein inhibits the reaction [Streptozocin results in increased expression of TRP53 mRNA]; SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of TRP53]
Streptozocin results in increased expression of TRP53; Streptozocin results in increased expression of TRP53 mRNA; Streptozocin results in increased expression of TRP53 protein
4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of TP53 protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of TP53 protein; dapagliflozin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TP53 protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of TP53 mRNA]; Glyburide inhibits the reaction [Streptozocin results in increased expression of TP53 protein]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of TP53 mRNA]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of TP53 protein]; Tropisetron inhibits the reaction [Streptozocin results in increased expression of TP53 protein]
Streptozocin results in increased expression of TP53 mRNA; Streptozocin results in increased expression of TP53 protein
CTD PMID:11375343 PMID:15976052 PMID:22744176 PMID:23792339 PMID:29059224 More... NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of TRPM4 mRNA CTD PMID:29127188 NCBI chr 7:44,952,579...44,983,495
Ensembl chr 7:44,952,056...44,983,204
JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 increases response to substance ISO TRPV4 protein results in increased susceptibility to Streptozocin CTD PMID:18234883 NCBI chr 5:114,760,213...114,796,497
Ensembl chr 5:114,760,213...114,796,482
JBrowse link
G Trpv5 transient receptor potential cation channel, subfamily V, member 5 multiple interactions
decreases expression
EXP formononetin inhibits the reaction [Streptozocin results in decreased expression of TRPV5 mRNA] CTD PMID:35315182 NCBI chr 6:41,628,595...41,658,158
Ensembl chr 6:41,629,107...41,657,703
JBrowse link
G Trpv6 transient receptor potential cation channel, subfamily V, member 6 decreases expression
multiple interactions
EXP Streptozocin results in decreased expression of TRPV6 mRNA
[bisphenol A co-treated with Streptozocin] results in increased expression of TRPV6 mRNA; [Ethinyl Estradiol co-treated with Streptozocin] results in increased expression of TRPV6 mRNA; formononetin inhibits the reaction [Streptozocin results in decreased expression of TRPV6 mRNA]
CTD PMID:29935216 PMID:35315182 NCBI chr 6:41,597,553...41,613,339
Ensembl chr 6:41,597,558...41,613,339
JBrowse link
G Try10 trypsin 10 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of PRSS1 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of PRSS1 mRNA] CTD PMID:33484791 NCBI chr 6:41,331,039...41,334,878
Ensembl chr 6:41,331,039...41,334,848
JBrowse link
G Tsc22d1 TSC22 domain family, member 1 decreases expression ISO Streptozocin results in decreased expression of TSC22D1 mRNA CTD PMID:25905778 NCBI chr14:76,652,401...76,745,205
Ensembl chr14:76,652,401...76,745,205
JBrowse link
G Tspan8 tetraspanin 8 multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of TSPAN8 mRNA CTD PMID:25905778 NCBI chr10:115,652,722...115,685,798
Ensembl chr10:115,652,737...115,685,798
JBrowse link
G Tspo translocator protein multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of TSPO mRNA CTD PMID:25905778 NCBI chr15:83,447,774...83,458,404
Ensembl chr15:83,447,793...83,458,404
JBrowse link
G Ttll8 tubulin tyrosine ligase-like family, member 8 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of TTLL8 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of TTLL8 mRNA] CTD PMID:33484791 NCBI chr15:88,773,981...88,839,258
Ensembl chr15:88,774,836...88,838,621
JBrowse link
G Ttr transthyretin decreases expression
multiple interactions
ISO Streptozocin results in decreased expression of TTR protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of TTR protein]
CTD PMID:19634143 NCBI chr18:20,797,266...20,807,383
Ensembl chr18:20,798,337...20,807,378
JBrowse link
G Txn1 thioredoxin 1 multiple interactions EXP TXN protein inhibits the reaction [Streptozocin results in increased secretion of ALB protein] CTD PMID:17360766 NCBI chr 4:57,943,373...57,956,411
Ensembl chr 4:57,943,373...57,956,411
JBrowse link
G Txnip thioredoxin interacting protein increases expression
multiple interactions
EXP
ISO
Streptozocin results in increased expression of TXNIP mRNA
Allopurinol inhibits the reaction [Streptozocin results in increased expression of TXNIP mRNA]; Allopurinol inhibits the reaction [Streptozocin results in increased expression of TXNIP protein]; Quercetin inhibits the reaction [Streptozocin results in increased expression of TXNIP mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of TXNIP protein]
Streptozocin results in increased expression of TXNIP mRNA; Streptozocin results in increased expression of TXNIP protein
[Streptozocin co-treated with Dietary Fats] results in increased expression of TXNIP protein; aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TXNIP protein]
CTD PMID:17582205 PMID:23647015 PMID:35961541 NCBI chr 3:96,465,273...96,469,173
Ensembl chr 3:96,465,273...96,469,199
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO Streptozocin results in increased expression of TXNRD1 mRNA CTD PMID:12398930 NCBI chr10:82,669,785...82,733,558
Ensembl chr10:82,669,785...82,733,546
JBrowse link
G Tyrobp TYRO protein tyrosine kinase binding protein multiple interactions ISO [resveratrol co-treated with Streptozocin] results in increased expression of TYROBP mRNA CTD PMID:25905778 NCBI chr 7:30,113,207...30,117,007
Ensembl chr 7:30,113,185...30,117,010
JBrowse link
G Uba1 ubiquitin-like modifier activating enzyme 1 increases expression
multiple interactions
ISO Streptozocin results in increased expression of UBA1 protein
4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of UBA1 protein]
CTD PMID:30980806 NCBI chr  X:20,524,660...20,549,420
Ensembl chr  X:20,524,565...20,549,418
JBrowse link
G Uchl1 ubiquitin carboxy-terminal hydrolase L1 decreases expression
multiple interactions
increases expression
ISO Streptozocin results in decreased expression of UCHL1 protein
4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of UCHL1 protein]
CTD PMID:30583000 PMID:30980806 NCBI chr 5:66,833,464...66,844,577
Ensembl chr 5:66,833,434...66,844,577
JBrowse link
G Uchl5 ubiquitin carboxyl-terminal esterase L5 increases expression
multiple interactions
ISO Streptozocin results in increased expression of UCHL5 protein
4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of UCHL5 protein]
CTD PMID:30980806 NCBI chr 1:143,652,993...143,683,204
Ensembl chr 1:143,653,010...143,683,204
JBrowse link
G Ucp2 uncoupling protein 2 (mitochondrial, proton carrier) multiple interactions EXP [Dietary Fats co-treated with Streptozocin] results in decreased expression of UCP2 mRNA CTD PMID:33359794 NCBI chr 7:100,142,565...100,148,832
Ensembl chr 7:100,142,544...100,151,227
JBrowse link
G Ucp3 uncoupling protein 3 (mitochondrial, proton carrier) increases expression EXP Streptozocin results in increased expression of UCP3 protein CTD PMID:16306367 NCBI chr 7:100,122,198...100,135,639
Ensembl chr 7:100,122,197...100,135,639
JBrowse link
G Ugt2b37 UDP glucuronosyltransferase 2 family, polypeptide B37 multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of UGT2B37 mRNA CTD PMID:33484791 NCBI chr 5:87,388,351...87,402,647
Ensembl chr 5:87,388,352...87,402,663
JBrowse link
G Uox urate oxidase affects expression EXP Streptozocin affects the expression of UOX mRNA CTD PMID:18583417 NCBI chr 3:146,302,904...146,337,238
Ensembl chr 3:146,276,181...146,338,060
JBrowse link
G Uqcrb ubiquinol-cytochrome c reductase binding protein multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of UQCRB mRNA; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of UQCRB mRNA] CTD PMID:37337224 NCBI chr13:67,048,640...67,053,414
Ensembl chr13:67,048,681...67,053,442
JBrowse link
G Uqcrc1 ubiquinol-cytochrome c reductase core protein 1 increases expression
multiple interactions
ISO Streptozocin results in increased expression of UQCRC1 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of UQCRC1 protein]
CTD PMID:19634143 PMID:21136691 NCBI chr 9:108,765,716...108,778,709
Ensembl chr 9:108,765,701...108,778,691
JBrowse link
G Usp15 ubiquitin specific peptidase 15 multiple interactions
increases expression
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [NFE2L2 protein inhibits the reaction [Streptozocin results in increased expression of USP15 protein]]; MIR497 inhibits the reaction [Streptozocin results in increased expression of USP15 mRNA]; MIR497 inhibits the reaction [Streptozocin results in increased expression of USP15 protein]; NFE2L2 protein inhibits the reaction [Streptozocin results in increased expression of USP15 protein]; USP15 protein inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; USP15 protein inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]
Streptozocin results in increased expression of USP15 mRNA; Streptozocin results in increased expression of USP15 protein
CTD PMID:35478295 NCBI chr10:122,940,911...123,032,924
Ensembl chr10:122,940,911...123,032,900
JBrowse link
G Usp16 ubiquitin specific peptidase 16 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of USP16 mRNA; esculetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of USP16 mRNA] CTD PMID:28946194 NCBI chr16:87,251,833...87,280,403
Ensembl chr16:87,251,591...87,280,405
JBrowse link
G Usp2 ubiquitin specific peptidase 2 increases expression ISO Streptozocin results in increased expression of USP2 mRNA CTD PMID:25905778 NCBI chr 9:43,978,318...44,006,924
Ensembl chr 9:43,978,318...44,006,924
JBrowse link
G Usp22 ubiquitin specific peptidase 22 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of USP22 mRNA; esculetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of USP22 mRNA] CTD PMID:28946194 NCBI chr11:61,042,607...61,065,885
Ensembl chr11:61,042,611...61,065,881
JBrowse link
G Usp27x ubiquitin specific peptidase 27, X chromosome multiple interactions
increases expression
ISO baicalin inhibits the reaction [Streptozocin results in increased expression of USP27X protein] CTD PMID:34414639 NCBI chr  X:7,238,830...7,242,069
Ensembl chr  X:7,237,513...7,242,069
JBrowse link
G Vamp2 vesicle-associated membrane protein 2 multiple interactions ISO [Streptozocin co-treated with Niacinamide] results in decreased expression of VAMP2 mRNA; resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of VAMP2 mRNA] CTD PMID:25999625 NCBI chr11:68,979,354...68,983,207
Ensembl chr11:68,979,316...68,983,210
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions
increases expression
ISO
EXP
[Streptozocin co-treated with Dietary Fats] results in increased expression of VCAM1 mRNA; Atorvastatin inhibits the reaction [Streptozocin results in increased expression of VCAM1 mRNA]; Atorvastatin inhibits the reaction [Streptozocin results in increased expression of VCAM1 protein]; Bezafibrate inhibits the reaction [Streptozocin results in increased expression of VCAM1 mRNA]; candesartan inhibits the reaction [Streptozocin results in increased expression of VCAM1 protein]; esculetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of VCAM1 mRNA]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of VCAM1 protein]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of VCAM1 mRNA]; procyanidin B2 inhibits the reaction [Streptozocin results in increased expression of VCAM1 mRNA]
Streptozocin results in increased expression of VCAM1 mRNA; Streptozocin results in increased expression of VCAM1 protein
[Streptozocin co-treated with Dietary Fats] results in increased expression of VCAM1 protein; Curcumin analog inhibits the reaction [Streptozocin results in increased expression of VCAM1 mRNA]; sulforaphane inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of VCAM1 protein]
CTD PMID:16129698 PMID:16139267 PMID:16979161 PMID:17589825 PMID:24707343 More... NCBI chr 3:115,903,669...115,923,337
Ensembl chr 3:115,903,598...115,923,337
JBrowse link
G Vcp valosin containing protein increases expression
multiple interactions
ISO Streptozocin results in increased expression of VCP protein
4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of VCP protein]
CTD PMID:30980806 NCBI chr 4:42,979,964...43,000,507
Ensembl chr 4:42,979,963...43,000,507
JBrowse link
G Vdac1 voltage-dependent anion channel 1 increases expression
multiple interactions
ISO Streptozocin results in increased expression of VDAC1 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of VDAC1 protein]
CTD PMID:19634143 NCBI chr11:52,251,905...52,280,224
Ensembl chr11:52,251,687...52,280,224
JBrowse link
G Vdac2 voltage-dependent anion channel 2 increases expression
multiple interactions
ISO Streptozocin results in increased expression of VDAC2 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of VDAC2 protein]
CTD PMID:19634143 NCBI chr14:21,881,629...21,895,947
Ensembl chr14:21,875,306...21,895,947
JBrowse link
G Vdr vitamin D (1,25-dihydroxyvitamin D3) receptor decreases expression
multiple interactions
ISO Streptozocin results in decreased expression of VDR mRNA; Streptozocin results in decreased expression of VDR protein
Calcitriol inhibits the reaction [Streptozocin results in decreased expression of VDR mRNA]; Calcitriol inhibits the reaction [Streptozocin results in decreased expression of VDR protein]
CTD PMID:29953732 NCBI chr15:97,752,308...97,806,177
Ensembl chr15:97,752,306...97,808,511
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions
decreases expression
increases expression
decreases secretion
EXP
ISO
bisphenol A inhibits the reaction [Streptozocin results in decreased secretion of VEGFA protein]; dehydroxymethylepoxyquinomicin inhibits the reaction [Streptozocin results in increased expression of VEGFA mRNA]; dehydroxymethylepoxyquinomicin inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]; Telmisartan inhibits the reaction [Streptozocin results in increased expression of VEGFA mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of VEGFA mRNA]
[Streptozocin co-treated with Cadmium] results in increased expression of VEGFA protein; ACE2 inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]; benazepril inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]; cloricromen inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of VEGFA mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]; manumycin inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]; Melatonin inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of VEGFA protein]; PD 123319 inhibits the reaction [Streptozocin results in increased expression of VEGFA mRNA]; PD 123319 inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]; procyanidin B2 inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of VEGFA mRNA]; Simvastatin inhibits the reaction [Streptozocin results in increased expression of VEGFA mRNA]; Simvastatin inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]; Taurine inhibits the reaction [Streptozocin results in decreased expression of VEGFA mRNA]; Thioctic Acid inhibits the reaction [Streptozocin results in decreased expression of VEGFA mRNA]; turmeric extract inhibits the reaction [Streptozocin results in increased expression of VEGFA mRNA]; turmeric extract inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]; Valsartan inhibits the reaction [Streptozocin results in increased expression of VEGFA mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]
Streptozocin results in increased expression of VEGFA mRNA; Streptozocin results in increased expression of VEGFA protein
CTD PMID:11596663 PMID:14718351 PMID:15643138 PMID:17662242 PMID:17724226 More... NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295
JBrowse link
G Vegfc vascular endothelial growth factor C decreases expression
multiple interactions
ISO Streptozocin results in decreased expression of VEGFC mRNA
baicalin inhibits the reaction [Streptozocin results in decreased expression of VEGFC mRNA]
CTD PMID:34414639 NCBI chr 8:54,530,567...54,639,489
Ensembl chr 8:54,530,641...54,640,131
JBrowse link
G Vim vimentin multiple interactions
increases expression
ISO carvedilol inhibits the reaction [Streptozocin results in increased expression of VIM protein] CTD PMID:12140129 NCBI chr 2:13,579,122...13,587,637
Ensembl chr 2:13,578,738...13,587,637
JBrowse link
G Vldlr very low density lipoprotein receptor multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of VLDLR mRNA CTD PMID:29127188 NCBI chr19:27,190,070...27,231,631
Ensembl chr19:27,193,884...27,231,631
JBrowse link
G Vnn1 vanin 1 multiple interactions ISO [Streptozocin co-treated with Fructose] results in increased expression of VNN1 mRNA; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of VNN1 mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of VNN1 mRNA] CTD PMID:30551545 NCBI chr10:23,770,586...23,781,242
Ensembl chr10:23,770,586...23,781,241
JBrowse link
G Vwa3b von Willebrand factor A domain containing 3B multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of VWA3B mRNA CTD PMID:33484791 NCBI chr 1:37,068,372...37,226,689
Ensembl chr 1:37,065,677...37,226,694
JBrowse link
G Wdr31 WD repeat domain 31 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of WDR31 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of WDR31 mRNA] CTD PMID:33484791 NCBI chr 4:62,366,890...62,389,236
Ensembl chr 4:62,366,890...62,389,133
JBrowse link
G Wdr35 WD repeat domain 35 increases expression ISO Streptozocin results in increased expression of WDR35 mRNA CTD PMID:20224876 NCBI chr12:9,023,897...9,078,848
Ensembl chr12:9,023,892...9,078,847
JBrowse link
G Wee1 WEE 1 homolog 1 (S. pombe) increases expression ISO Streptozocin results in increased expression of WEE1 mRNA CTD PMID:25905778 NCBI chr 7:109,721,266...109,742,506
Ensembl chr 7:109,721,253...109,742,493
JBrowse link
G Wnt3a wingless-type MMTV integration site family, member 3A decreases expression
multiple interactions
EXP Streptozocin results in decreased expression of WNT3A protein
5-Methoxypsoralen inhibits the reaction [Streptozocin results in decreased expression of WNT3A protein]; Tadalafil inhibits the reaction [Streptozocin results in decreased expression of WNT3A protein]
CTD PMID:34428446 NCBI chr11:59,138,859...59,181,579
Ensembl chr11:59,138,859...59,181,578
JBrowse link
G Wsb1 WD repeat and SOCS box-containing 1 decreases expression ISO Streptozocin results in decreased expression of WSB1 mRNA CTD PMID:25905778 NCBI chr11:79,130,208...79,145,521
Ensembl chr11:79,130,198...79,145,497
JBrowse link
G Xbp1 X-box binding protein 1 multiple interactions ISO
EXP
[Streptozocin co-treated with Dietary Fats] results in decreased expression of XBP1 mRNA alternative form; Bilirubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of XBP1 mRNA alternative form]; moutan cortex inhibits the reaction [Streptozocin results in increased expression of and results in increased secretion of XBP1 protein alternative form]; Streptozocin results in increased expression of and results in increased secretion of XBP1 protein alternative form
[Dietary Fats co-treated with Streptozocin] results in increased splicing of XBP1 mRNA; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased splicing of XBP1 mRNA]
CTD PMID:27664441 PMID:33812996 PMID:37054934 NCBI chr11:5,470,641...5,475,993
Ensembl chr11:5,470,659...5,475,893
JBrowse link
G Xdh xanthine dehydrogenase multiple interactions
affects activity
increases expression
increases activity
ISO [Propolis co-treated with Chlorpyrifos co-treated with Streptozocin] results in increased activity of XDH protein modified form; [Propolis co-treated with Chlorpyrifos co-treated with Streptozocin] results in increased expression of XDH mRNA; [Streptozocin affects the activity of XDH protein] which results in increased chemical synthesis of Hydrogen Peroxide; [Streptozocin co-treated with Chlorpyrifos] inhibits the reaction [Propolis results in decreased activity of XDH protein modified form]; [Streptozocin co-treated with Chlorpyrifos] inhibits the reaction [Propolis results in decreased expression of XDH mRNA]; [Streptozocin co-treated with Chlorpyrifos] results in increased activity of XDH protein modified form; [Streptozocin co-treated with Chlorpyrifos] results in increased expression of XDH mRNA; Allopurinol inhibits the reaction [[Streptozocin affects the activity of XDH protein] which results in increased chemical synthesis of Hydrogen Peroxide]; Allopurinol inhibits the reaction [Streptozocin affects the activity of XDH protein]; Chlorpyrifos promotes the reaction [Streptozocin results in increased expression of XDH mRNA]; Propolis inhibits the reaction [[Streptozocin co-treated with Chlorpyrifos] results in increased activity of XDH protein modified form]; Propolis inhibits the reaction [[Streptozocin co-treated with Chlorpyrifos] results in increased expression of XDH mRNA]; Propolis inhibits the reaction [Streptozocin results in increased activity of XDH protein modified form]; Propolis inhibits the reaction [Streptozocin results in increased expression of XDH mRNA]; Quercetin inhibits the reaction [[Streptozocin affects the activity of XDH protein] which results in increased chemical synthesis of Hydrogen Peroxide]; Quercetin inhibits the reaction [Streptozocin affects the activity of XDH protein]; Streptozocin inhibits the reaction [Propolis results in decreased activity of XDH protein modified form]; Streptozocin inhibits the reaction [Propolis results in decreased expression of XDH mRNA]; Streptozocin promotes the reaction [Chlorpyrifos results in increased activity of XDH protein modified form]; Streptozocin promotes the reaction [Chlorpyrifos results in increased expression of XDH mRNA]
Streptozocin results in increased activity of XDH protein; Streptozocin results in increased activity of XDH protein modified form
CTD PMID:23647015 PMID:31400774 PMID:32812462 PMID:37354076 NCBI chr17:74,190,890...74,257,191
Ensembl chr17:74,190,890...74,257,191
JBrowse link
G Xiap X-linked inhibitor of apoptosis increases expression ISO Streptozocin results in increased expression of XIAP protein CTD PMID:15976052 NCBI chr  X:41,148,483...41,198,541
Ensembl chr  X:41,148,556...41,198,533
JBrowse link
G Zbed4-ps1 zinc finger, BED type containing 4, pseudogene 1 multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of ZBED4-PS1 mRNA CTD PMID:33484791 NCBI chr 7:13,372,832...13,376,724
Ensembl chr 7:13,373,032...13,376,497
JBrowse link
G Zcchc18 zinc finger, CCHC domain containing 18 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of ZCCHC18 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ZCCHC18 mRNA] CTD PMID:33484791 NCBI chr  X:135,893,128...135,899,221
Ensembl chr  X:135,893,904...135,899,221
JBrowse link
G Zdhhc23 zinc finger, DHHC domain containing 23 multiple interactions ISO [resveratrol co-treated with Streptozocin] results in decreased expression of ZDHHC23 mRNA CTD PMID:25905778 NCBI chr16:43,785,396...43,800,295
Ensembl chr16:43,785,396...43,800,154
JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 decreases expression
multiple interactions
EXP
ISO
Streptozocin results in decreased expression of ZEB2 mRNA
SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of ZEB2 mRNA]
CTD PMID:27629361 NCBI chr 2:44,873,523...45,007,378
Ensembl chr 2:44,873,644...45,007,407
JBrowse link
G Zfp184 zinc finger protein 184 (Kruppel-like) multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in increased expression of ZFP184 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of ZFP184 mRNA] CTD PMID:33484791 NCBI chr13:22,129,223...22,144,961
Ensembl chr13:22,129,264...22,144,949
JBrowse link
G Zfp239 zinc finger protein 239 multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of ZFP239 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ZFP239 mRNA] CTD PMID:33484791 NCBI chr 6:117,838,907...117,849,727
Ensembl chr 6:117,839,061...117,850,252
JBrowse link
G Zpbp2 zona pellucida binding protein 2 multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of ZPBP2 mRNA CTD PMID:33484791 NCBI chr11:98,441,923...98,449,491
Ensembl chr11:98,441,923...98,449,491
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22327
    role 22313
      biological role 22312
        antimicrobial agent 19667
          streptozocin 1243
Path 2
Term Annotations click to browse term
  CHEBI ontology 22327
    subatomic particle 22322
      composite particle 22322
        hadron 22322
          baryon 22322
            nucleon 22322
              atomic nucleus 22322
                atom 22322
                  main group element atom 22209
                    p-block element atom 22209
                      carbon group element atom 22015
                        carbon atom 21958
                          organic molecular entity 21958
                            heteroorganic entity 21604
                              organochalcogen compound 21109
                                organooxygen compound 20946
                                  carbon oxoacid 19736
                                    carboxylic acid 19732
                                      carboacyl group 18298
                                        univalent carboacyl group 18298
                                          carbamoyl group 18112
                                            carboxamide 18112
                                              monocarboxylic acid amide 15891
                                                urea 6396
                                                  ureas 6394
                                                    N-nitrosoureas 2274
                                                      streptozocin 1243
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