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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:streptozocin
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Accession:CHEBI:9288 term browser browse the term
Definition:An N-nitrosourea that is an antibiotic produced by Streptomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animals.
Synonyms:exact_synonym: 2-deoxy-2-{[methyl(nitroso)carbamoyl]amino}-alpha-D-glucopyranose
 related_synonym: 2-Deoxy-2-(((methylnitrosoamino)carbonyl)amino)-D-glucopyranose;   2-Deoxy-2-(3-methyl-3-nitrosoureido)-D-glucopyranose;   Formula=C8H15N3O7;   InChI=1S/C8H15N3O7/c1-11(10-17)8(16)9-4-6(14)5(13)3(2-12)18-7(4)15/h3-7,12-15H,2H2,1H3,(H,9,16)/t3-,4-,5-,6-,7+/m1/s1;   InChIKey=ZSJLQEPLLKMAKR-GKHCUFPYSA-N;   N-D-Glucosyl-(2)-N'-nitrosomethylharnstoff;   N-D-Glucosyl-(2)-N'-nitrosomethylurea;   SMILES=CN(N=O)C(=O)N[C@H]1[C@@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O;   Streptozocinium;   Streptozotocin;   Zanosar;   estreptozocina;   streptozocine;   streptozocinum
 xref: Beilstein:2060675;   CAS:18883-66-4;   DrugBank:DB00428;   HMDB:HMDB0014572;   KEGG:C07313;   KEGG:D05932
 xref_mesh: MESH:D013311
 xref: PMID:12613763;   PMID:23151907;   PMID:23333576;   PMID:23600389;   PMID:23612842;   PMID:23662406;   PMID:2954873;   Patent:FR1434920;   Patent:US2005271747;   Patent:US2005272738;   Patent:US2008085882;   Patent:US4156777;   Reaxys:2060675;   Wikipedia:Streptozocin


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streptozocin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of A2M mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of A2M mRNA] CTD PMID:33484791 NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786 		JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 multiple interactions EXP [[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in decreased expression of ABCA1 mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of ABCA1 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of ABCA1 mRNA CTD PMID:35786680 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170 		JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 increases activity
increases expression		 EXP
ISO		 Streptozocin results in increased activity of ABCB11 protein
Streptozocin results in increased expression of ABCB11 protein		 CTD PMID:12055592 PMID:23319174 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730 		JBrowse link
G Abcb1b ATP-binding cassette, sub-family B member 1B decreases expression
increases expression		 ISO Streptozocin results in decreased expression of ABCB1B mRNA; Streptozocin results in decreased expression of ABCB1B protein
Streptozocin results in increased expression of ABCB1B protein		 CTD PMID:22531820 PMID:23319174 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199 		JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 increases expression EXP Streptozocin results in increased expression of ABCB4 mRNA; Streptozocin results in increased expression of ABCB4 protein CTD PMID:12055592 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202 		JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 increases expression ISO Streptozocin results in increased expression of ABCC1 mRNA; Streptozocin results in increased expression of ABCC1 protein CTD PMID:22531820 PMID:23319174 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression EXP
ISO		 Streptozocin results in increased expression of ABCC2 mRNA
Streptozocin results in increased expression of ABCC2 mRNA; Streptozocin results in increased expression of ABCC2 protein		 CTD PMID:11752103 PMID:22531820 PMID:23319174 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 decreases expression
increases expression
multiple interactions		 ISO
EXP		 Streptozocin results in decreased expression of ABCC3 mRNA
Streptozocin results in increased expression of ABCC3 mRNA; Streptozocin results in increased expression of ABCC3 protein
[resveratrol co-treated with Streptozocin] results in increased expression of ABCC3 mRNA		 CTD PMID:22531820 PMID:23319174 PMID:25905778 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595 		JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 increases expression
multiple interactions		 ISO Streptozocin results in increased expression of ABCC4 mRNA; Streptozocin results in increased expression of ABCC4 protein
[Dietary Fats co-treated with Streptozocin] results in increased expression of ABCC4 mRNA		 CTD PMID:22531820 PMID:23319174 PMID:29382564 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283 		JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 increases expression ISO Streptozocin results in increased expression of ABCC5 mRNA; Streptozocin results in increased expression of ABCC5 protein CTD PMID:22531820 PMID:23319174 NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253 		JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 decreases expression ISO Streptozocin results in decreased expression of ABCC6 protein CTD PMID:22531820 NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 increases expression ISO Streptozocin results in increased expression of ABCG2 mRNA; Streptozocin results in increased expression of ABCG2 protein CTD PMID:23319174 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409 		JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 increases expression ISO Streptozocin results in increased expression of ABCG5 mRNA CTD PMID:23319174 NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563 		JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 increases expression ISO Streptozocin results in increased expression of ABCG8 mRNA CTD PMID:23319174 NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912 		JBrowse link
G Abhd2 abhydrolase domain containing 2, acylglycerol lipase multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of ABHD2 mRNA CTD PMID:29127188 NCBI chr 1:133,217,403...133,298,564
Ensembl chr 1:133,217,375...133,299,061 		JBrowse link
G Acaca acetyl-CoA carboxylase alpha multiple interactions
decreases expression
decreases activity
increases expression		 EXP
ISO		 Fructose inhibits the reaction [Streptozocin results in decreased activity of ACACA protein]; Fructose inhibits the reaction [Streptozocin results in decreased expression of ACACA mRNA]; Triiodothyronine inhibits the reaction [Streptozocin results in decreased activity of ACACA protein]; Triiodothyronine inhibits the reaction [Streptozocin results in decreased expression of ACACA mRNA]
Streptozocin results in increased expression of ACACA mRNA
[Dietary Fats co-treated with Streptozocin] results in increased expression of ACACA mRNA; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of ACACA mRNA]		 CTD PMID:1973097 PMID:28822685 PMID:33812996 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457 		JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of ACADM protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of ACADM protein]		 CTD PMID:19634143 NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147 		JBrowse link
G Acat1 acetyl-CoA acetyltransferase 1 decreases expression
multiple interactions		 EXP
ISO		 Streptozocin results in decreased expression of ACAT1 protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of ACAT1 protein]
Acrylamide inhibits the reaction [Streptozocin results in decreased expression of ACAT1 mRNA]		 CTD PMID:19634143 PMID:34896238 NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855 		JBrowse link
G Acbd6 acyl-CoA binding domain containing 6 increases expression EXP Streptozocin results in increased expression of ACBD6 mRNA CTD PMID:25905778 NCBI chr13:67,726,786...67,863,392
Ensembl chr13:67,726,786...67,862,311 		JBrowse link
G Ace angiotensin I converting enzyme multiple interactions
increases expression
increases activity		 EXP
ISO		 [INS1 protein co-treated with Pravastatin] inhibits the reaction [Streptozocin results in increased expression of ACE protein]; Bezafibrate inhibits the reaction [Streptozocin results in increased expression of ACE mRNA]; Bezafibrate inhibits the reaction [Streptozocin results in increased expression of ACE protein]; Enalapril inhibits the reaction [Streptozocin results in increased expression of ACE mRNA]; Enalapril inhibits the reaction [Streptozocin results in increased expression of ACE protein]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of ACE mRNA]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of ACE protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of ACE mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of ACE mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of ACE protein]
Streptozocin results in increased expression of ACE mRNA; Streptozocin results in increased expression of ACE protein
Streptozocin results in increased activity of ACE protein
2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of ACE mRNA]; [Streptozocin co-treated with Niacinamide] results in increased expression of ACE mRNA; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of ACE protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of ACE mRNA]		 CTD PMID:15793251 PMID:16979161 PMID:22191573 PMID:23733546 PMID:28468961 More... NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131 		JBrowse link
G Ace2 angiotensin converting enzyme 2 decreases expression
multiple interactions
increases activity		 ISO
EXP		 Streptozocin results in decreased expression of ACE2 protein
2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of ACE2 mRNA]; [Streptozocin co-treated with Niacinamide] results in decreased expression of ACE2 mRNA; CEBPB protein inhibits the reaction [Streptozocin results in decreased expression of ACE2 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of ACE2 mRNA]; Telmisartan inhibits the reaction [Streptozocin results in decreased expression of ACE2 protein]
[INS1 protein co-treated with Pravastatin] inhibits the reaction [Streptozocin results in decreased expression of ACE2 protein]; ACE2 inhibits the reaction [Streptozocin results in increased expression of AGT protein modified form]; ACE2 inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; ACE2 inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]
Streptozocin results in increased activity of ACE2 protein		 CTD PMID:20844835 PMID:21381899 PMID:28468961 PMID:29266779 PMID:29682576 More... NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977 		JBrowse link
G Acer2 alkaline ceramidase 2 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of ACER2 mRNA CTD PMID:25905778 NCBI chr 5:101,391,830...101,442,615
Ensembl chr 5:101,391,885...101,442,614 		JBrowse link
G Ache acetylcholinesterase multiple interactions
increases activity
decreases activity		 ISO
EXP		 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Lisinopril inhibits the reaction [Streptozocin results in increased activity of ACHE protein]]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Telmisartan inhibits the reaction [Streptozocin results in increased activity of ACHE protein]]; Acetylcysteine inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Alendronate inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Curcumin inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Donepezil inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Genistein inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Indinavir inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Lisinopril inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Physostigmine inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Telmisartan inhibits the reaction [Streptozocin results in increased activity of ACHE protein]
[Fructose co-treated with Streptozocin] results in increased expression of ACHE protein; [Propolis co-treated with Chlorpyrifos co-treated with Streptozocin] results in decreased activity of ACHE protein; [Propolis co-treated with Streptozocin] inhibits the reaction [Chlorpyrifos results in decreased activity of ACHE protein]; [Streptozocin co-treated with Chlorpyrifos] results in decreased activity of ACHE protein; [Streptozocin co-treated with Dietary Fats] results in increased activity of ACHE protein; alpha-Tocopherol inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Canagliflozin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased activity of ACHE protein]; Chlorpyrifos inhibits the reaction [Streptozocin results in decreased activity of ACHE protein]; Donepezil inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; geraniol inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Melatonin inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Metformin inhibits the reaction [[Fructose co-treated with Streptozocin] results in increased expression of ACHE protein]; Phycocyanin inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Propolis inhibits the reaction [[Streptozocin co-treated with Chlorpyrifos] results in decreased activity of ACHE protein]; Propolis inhibits the reaction [Streptozocin results in decreased activity of ACHE protein]; pyrazolanthrone inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Rivastigmine inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Streptozocin inhibits the reaction [Chlorpyrifos results in decreased activity of ACHE protein]; Streptozocin promotes the reaction [[Propolis co-treated with Chlorpyrifos] results in decreased activity of ACHE protein]; Tocotrienols inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; vanillin inhibits the reaction [[Fructose co-treated with Streptozocin] results in increased expression of ACHE protein]		 CTD PMID:18208924 PMID:18343489 PMID:19464315 PMID:19705549 PMID:20369229 More... NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Acmsd aminocarboxymuconate semialdehyde decarboxylase increases activity
increases expression		 EXP Streptozocin results in increased activity of ACMSD protein
Streptozocin results in increased expression of ACMSD mRNA		 CTD PMID:12042425 NCBI chr13:39,200,412...39,245,954
Ensembl chr13:39,200,314...39,245,209 		JBrowse link
G Aco2 aconitase 2 decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of ACO2 protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of ACO2 protein]		 CTD PMID:19634143 NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261 		JBrowse link
G Acot1 acyl-CoA thioesterase 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of ACOT1 mRNA CTD PMID:29127188 NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163 		JBrowse link
G Acot2 acyl-CoA thioesterase 2 multiple interactions EXP
ISO		 [resveratrol co-treated with Streptozocin] results in decreased expression of ACOT2 mRNA
[Streptozocin co-treated with Dietary Fats] results in increased expression of ACOT2 mRNA		 CTD PMID:25905778 PMID:29127188 NCBI chr 6:103,611,738...103,619,404
Ensembl chr 6:103,611,544...103,619,245 		JBrowse link
G Acot9 acyl-CoA thioesterase 9 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of ACOT9 mRNA CTD PMID:29127188 NCBI chr  X:40,073,197...40,123,573
Ensembl chr  X:40,064,810...40,123,559 		JBrowse link
G Acox1 acyl-CoA oxidase 1 multiple interactions EXP [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of ACOX1 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of ACOX1 mRNA CTD PMID:35786680 NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232 		JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant increases expression
multiple interactions
increases activity		 ISO Streptozocin results in increased expression of ACP5 mRNA
formononetin inhibits the reaction [Streptozocin results in increased activity of ACP5 protein]; formononetin inhibits the reaction [Streptozocin results in increased expression of ACP5 mRNA]		 CTD PMID:35315182 NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929 		JBrowse link
G Acsm2 acyl-CoA synthetase medium-chain family member 2 increases expression EXP Streptozocin results in increased expression of ACSM2 mRNA CTD PMID:25905778 NCBI chr 1:173,916,368...173,955,116
Ensembl chr 1:173,916,368...173,955,116 		JBrowse link
G Acss1 acyl-CoA synthetase short-chain family member 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of ACSS1 mRNA CTD PMID:29127188 NCBI chr 3:139,450,383...139,500,325
Ensembl chr 3:139,450,383...139,500,325 		JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions
increases expression
decreases expression		 EXP
ISO		 [Streptozocin co-treated with Fructose] results in increased expression of ACTA2 protein; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of ACTA2 protein]; Metformin promotes the reaction [dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of ACTA2 protein]]
[Dietary Fats co-treated with Streptozocin] results in increased expression of ACTA2 mRNA; [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of ACTA2 mRNA]; [Streptozocin co-treated with fatostatin] results in increased expression of ACTA2 protein; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of ACTA2 mRNA; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of ACTA2 protein; bisphenol A inhibits the reaction [Streptozocin results in decreased expression of ACTA2 protein]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of ACTA2 mRNA]
Streptozocin results in increased expression of ACTA2 protein		 CTD PMID:29420703 PMID:29988851 PMID:30551545 PMID:35051763 PMID:35993117 More... NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Actc1 actin, alpha, cardiac muscle 1 decreases expression EXP Streptozocin results in decreased expression of ACTC1 protein CTD PMID:21136691 NCBI chr 3:100,811,987...100,817,523
Ensembl chr 3:100,811,987...100,817,523 		JBrowse link
G Actn4 actinin alpha 4 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of ACTN4 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of ACTN4 protein]		 CTD PMID:19634143 NCBI chr 1:84,182,783...84,251,867
Ensembl chr 1:84,182,788...84,251,847 		JBrowse link
G Acy1 aminoacylase 1 multiple interactions
decreases expression		 EXP Trientine inhibits the reaction [Streptozocin results in decreased expression of ACY1 protein] CTD PMID:19634143 NCBI chr 8:107,072,354...107,077,756
Ensembl chr 8:107,072,358...107,077,682 		JBrowse link
G Ada adenosine deaminase increases activity
multiple interactions		 EXP Streptozocin results in increased activity of ADA protein
[Zinc Sulfate results in increased abundance of Zinc] inhibits the reaction [Streptozocin results in increased activity of ADA protein]		 CTD PMID:32864810 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088 		JBrowse link
G Adam17 ADAM metallopeptidase domain 17 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of ADAM17 mRNA; Streptozocin results in increased expression of ADAM17 protein
Diosgenin inhibits the reaction [Streptozocin results in increased expression of ADAM17 mRNA]; Diosgenin inhibits the reaction [Streptozocin results in increased expression of ADAM17 protein]		 CTD PMID:35305976 NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639 		JBrowse link
G Adgre1 adhesion G protein-coupled receptor E1 multiple interactions
increases expression		 EXP
ISO		 stannous mesoporphyrin inhibits the reaction [4-(4-(3-adamantan-1-ylureido)cyclohexyloxy)benzoic acid inhibits the reaction [Streptozocin results in increased expression of ADGRE1 protein]]
[fatostatin co-treated with Streptozocin] results in increased expression of ADGRE1 mRNA
Streptozocin results in increased expression of ADGRE1 mRNA		 CTD PMID:23611540 PMID:29420703 NCBI chr 9:2,242,476...2,398,000
Ensembl chr 9:2,242,474...2,398,000 		JBrowse link
G Adgrg7 adhesion G protein-coupled receptor G7 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of ADGRG7 mRNA CTD PMID:33484791 NCBI chr11:43,808,101...43,877,539
Ensembl chr11:43,813,801...43,876,316 		JBrowse link
G Adh1c alcohol dehydrogenase 1C (class I), gamma polypeptide increases expression EXP Streptozocin results in increased expression of ADH1 mRNA CTD PMID:25905778 NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions
decreases expression
decreases secretion		 EXP
ISO		 1,3-dimethoxy-5-methyl-2-(3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl)benzene inhibits the reaction [4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in decreased secretion of ADIPOQ protein]]; 4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in decreased secretion of ADIPOQ protein]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of ADIPOQ protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of ADIPOQ protein; Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOQ mRNA]; Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOQ protein]; Allopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOQ mRNA]]; Allopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOQ protein]]; cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of ADIPOQ protein]; geraniol promotes the reaction [Streptozocin results in decreased expression of ADIPOQ protein]; morin analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of ADIPOQ protein]; Warfarin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of ADIPOQ protein]; Zinc Compounds inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein]
Streptozocin results in decreased expression of ADIPOQ mRNA; Streptozocin results in decreased expression of ADIPOQ protein
[Dietary Fats co-treated with Streptozocin] results in decreased expression of and results in decreased secretion of ADIPOQ protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of and results in decreased secretion of ADIPOQ protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein]; omaveloxolone analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein]		 CTD PMID:17270171 PMID:21439372 PMID:21912612 PMID:22675305 PMID:24854284 More... NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Adipor1 adiponectin receptor 1 decreases expression
multiple interactions
increases expression		 EXP Streptozocin results in decreased expression of ADIPOR1 protein
1,3-dimethoxy-5-methyl-2-(3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl)benzene inhibits the reaction [4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in increased expression of ADIPOR1 protein]]; 4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in increased expression of ADIPOR1 protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of ADIPOR1 protein]		 CTD PMID:17270171 PMID:24413998 PMID:29274332 NCBI chr13:45,859,461...45,879,248
Ensembl chr13:45,859,533...45,879,241 		JBrowse link
G Adipor2 adiponectin receptor 2 multiple interactions
decreases expression		 EXP Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOR2 protein]; Allopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOR2 protein]] CTD PMID:21912612 NCBI chr 4:152,524,604...152,588,848
Ensembl chr 4:152,524,623...152,559,355 		JBrowse link
G Adora2a adenosine A2a receptor increases expression ISO Streptozocin results in increased expression of ADORA2A protein CTD PMID:26654777 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386 		JBrowse link
G Adra1a adrenoceptor alpha 1A increases expression EXP Streptozocin results in increased expression of ADRA1A mRNA; Streptozocin results in increased expression of ADRA1A protein CTD PMID:19133277 NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500 		JBrowse link
G Adra1b adrenoceptor alpha 1B increases expression EXP Streptozocin results in increased expression of ADRA1B mRNA CTD PMID:19298542 NCBI chr10:28,255,025...28,373,418
Ensembl chr10:28,255,025...28,312,919 		JBrowse link
G Adra1d adrenoceptor alpha 1D decreases expression EXP Streptozocin results in decreased expression of ADRA1D mRNA CTD PMID:19298542 NCBI chr 3:118,793,356...118,809,354
Ensembl chr 3:118,793,346...118,809,354 		JBrowse link
G Adrb1 adrenoceptor beta 1 multiple interactions
decreases expression		 EXP Metoprolol inhibits the reaction [Streptozocin results in decreased expression of ADRB1 protein] CTD PMID:18703049 NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259 		JBrowse link
G Adrb2 adrenoceptor beta 2 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of ADRB2 protein
Metoprolol promotes the reaction [Streptozocin results in increased expression of ADRB2 protein]		 CTD PMID:18703049 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512 		JBrowse link
G Adrb3 adrenoceptor beta 3 multiple interactions
increases expression		 EXP Metoprolol promotes the reaction [Streptozocin results in increased expression of ADRB3 protein] CTD PMID:18703049 NCBI chr16:64,839,820...64,844,552
Ensembl chr16:64,841,788...64,844,552 		JBrowse link
G Afmid arylformamidase increases expression EXP Streptozocin results in increased expression of AFMID mRNA CTD PMID:25905778 NCBI chr10:103,046,129...103,061,718
Ensembl chr10:103,046,180...103,061,718 		JBrowse link
G Afp alpha-fetoprotein multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of AFP mRNA CTD PMID:29127188 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480 		JBrowse link
G Ager advanced glycosylation end product-specific receptor increases expression
multiple interactions
increases response to substance		 EXP
ISO		 Streptozocin results in increased expression of AGER mRNA; Streptozocin results in increased expression of AGER protein
[Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of AGER protein]; [Streptozocin co-treated with Dietary Fats] results in increased expression of AGER protein; Dimethyl Fumarate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of AGER protein]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of AGER protein]; Kangen-karyu inhibits the reaction [Streptozocin results in increased expression of AGER protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of AGER protein]; procyanidin B2 inhibits the reaction [Streptozocin results in increased expression of AGER protein]; Sodium Selenite inhibits the reaction [Streptozocin results in increased expression of AGER protein]; Zinc inhibits the reaction [Streptozocin results in increased expression of AGER mRNA]
manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Streptozocin results in increased expression of AGER mRNA]
AGER protein results in increased susceptibility to Streptozocin		 CTD PMID:19397970 PMID:19833897 PMID:22476978 PMID:25199697 PMID:27109771 More... NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Agrp agouti related neuropeptide multiple interactions
increases expression		 EXP INS protein inhibits the reaction [Streptozocin results in increased expression of AGRP mRNA] CTD PMID:20219977 NCBI chr19:33,447,992...33,481,602
Ensembl chr19:33,447,992...33,449,584 		JBrowse link
G Agt angiotensinogen multiple interactions
increases expression
decreases abundance		 ISO
EXP		 CEBPB protein affects the reaction [Streptozocin results in increased expression of AGT protein]; CEBPB protein inhibits the reaction [Streptozocin results in decreased abundance of AGT protein modified form]; IGF1 protein inhibits the reaction [Streptozocin results in increased expression of AGT protein]; Valsartan inhibits the reaction [Streptozocin results in decreased abundance of AGT protein modified form]; Valsartan promotes the reaction [Streptozocin results in increased expression of AGT protein]
ACE2 inhibits the reaction [Streptozocin results in increased expression of AGT protein modified form]; AGT protein modified form inhibits the reaction [Streptozocin results in decreased abundance of Cyclic GMP]; AGT protein modified form inhibits the reaction [Streptozocin results in increased expression of PDE5 mRNA]; benazepril inhibits the reaction [Streptozocin results in increased expression of AGT protein modified form]; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in increased expression of AGT protein]
Streptozocin results in increased expression of AGT mRNA; Streptozocin results in increased expression of AGT protein; Streptozocin results in increased expression of AGT protein modified form		 CTD PMID:11375343 PMID:15643138 PMID:17724226 PMID:18487452 PMID:20547220 More... NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a multiple interactions
increases expression		 ISO
EXP		 2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of AGTR1A mRNA]; [Perindopril co-treated with AM6545] inhibits the reaction [Streptozocin results in increased expression of AGTR1A protein]; [Streptozocin co-treated with Niacinamide] results in increased expression of AGTR1A mRNA; AM6545 inhibits the reaction [Streptozocin results in increased expression of AGTR1A mRNA]; AM6545 inhibits the reaction [Streptozocin results in increased expression of AGTR1A protein]; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of AGTR1 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of AGTR1A mRNA]; Perindopril inhibits the reaction [Streptozocin results in increased expression of AGTR1A mRNA]; Perindopril inhibits the reaction [Streptozocin results in increased expression of AGTR1A protein]; Telmisartan inhibits the reaction [Streptozocin results in increased expression of AGTR1A protein]; Valsartan promotes the reaction [Streptozocin results in increased expression of AGTR1 protein]
Streptozocin results in increased expression of AGTR1 protein; Streptozocin results in increased expression of AGTR1A mRNA; Streptozocin results in increased expression of AGTR1A protein
[Streptozocin co-treated with Dietary Fats] results in increased expression of AGTR1A mRNA; esculetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of AGTR1A mRNA]		 CTD PMID:17724226 PMID:18487452 PMID:21381899 PMID:28946194 PMID:29266779 More... NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946 		JBrowse link
G Agtr2 angiotensin II receptor, type 2 increases expression
multiple interactions		 ISO
EXP		 Streptozocin results in increased expression of AGTR2 mRNA; Streptozocin results in increased expression of AGTR2 protein
[Streptozocin co-treated with Dietary Fats] results in increased expression of AGTR2 mRNA; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in increased expression of AGTR2 mRNA]; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in increased expression of AGTR2 protein]; esculetin promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of AGTR2 mRNA]
CEBPB protein inhibits the reaction [Streptozocin results in increased expression of AGTR2 protein]; Valsartan inhibits the reaction [Streptozocin results in increased expression of AGTR2 protein]		 CTD PMID:15587404 PMID:17724226 PMID:28946194 PMID:29266779 NCBI chr  X:112,119,876...112,124,060
Ensembl chr  X:112,120,228...112,124,057 		JBrowse link
G Agxt2 alanine-glyoxylate aminotransferase 2 multiple interactions
decreases expression		 EXP Trientine inhibits the reaction [Streptozocin results in decreased expression of AGXT2 protein] CTD PMID:19634143 NCBI chr 2:59,336,252...59,377,664
Ensembl chr 2:59,336,283...59,377,926 		JBrowse link
G Ahcy adenosylhomocysteinase multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of AHCY mRNA; [Streptozocin co-treated with Dietary Fats] results in increased methylation of AHCY gene CTD PMID:29127188 NCBI chr 3:143,569,134...143,584,359
Ensembl chr 3:143,569,094...143,584,393 		JBrowse link
G Ahr aryl hydrocarbon receptor decreases expression ISO Streptozocin results in decreased expression of AHR mRNA CTD PMID:22531820 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 increases expression
multiple interactions		 EXP
ISO		 Streptozocin results in increased expression of AIFM1 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of AIFM1 protein]
[Streptozocin co-treated with NQO1 protein mutant form] results in increased expression of AIFM1 protein; FGF21 protein affects the reaction [Streptozocin results in increased expression of AIFM1]		 CTD PMID:19634143 PMID:23458895 PMID:23499715 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256 		JBrowse link
G Ajm1 apical junction component 1 homolog multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of AJM1 mRNA CTD PMID:33484791 NCBI chr 3:8,394,942...8,401,323
Ensembl chr 3:8,392,889...8,401,321 		JBrowse link
G Ak4 adenylate kinase 4 decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of AK4 protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of AK4 protein]		 CTD PMID:19634143 NCBI chr 5:116,039,222...116,099,064
Ensembl chr 5:116,039,616...116,098,618 		JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of AKR1A1 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of AKR1A1 protein]		 CTD PMID:19634143 NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674 		JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B1 multiple interactions ISO Streptozocin inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK1 protein]; Streptozocin inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK3 protein]; Streptozocin inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK8 protein]; Streptozocin inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK9 protein] CTD PMID:25541468 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157 		JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 multiple interactions EXP
ISO		 [resveratrol co-treated with Streptozocin] results in decreased expression of AKR1C3 mRNA
[Streptozocin co-treated with Dietary Fats] results in increased expression of AKR1C18 mRNA		 CTD PMID:25905778 PMID:29127188 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873 		JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 increases expression EXP Streptozocin results in increased expression of AKR7A3 mRNA CTD PMID:25905778 NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
decreases expression
decreases phosphorylation
increases phosphorylation
increases expression		 EXP
ISO		 [cobaltiprotoporphyrin co-treated with Streptozocin] results in increased phosphorylation of AKT1 protein; [Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of AKT1 protein; [Dietary Fats co-treated with Streptozocin] results in increased phosphorylation of AKT1 protein; [Resveratrol co-treated with Streptozocin] results in decreased phosphorylation of AKT1 protein; [Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in decreased phosphorylation of AKT1 protein; [Streptozocin co-treated with Niacinamide] results in decreased phosphorylation of AKT1 protein; asiatic acid inhibits the reaction [Streptozocin results in decreased expression of AKT1 protein]; cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased phosphorylation of AKT1 protein]; Curcumin inhibits the reaction [Streptozocin results in decreased phosphorylation of AKT1 protein]; dapagliflozin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of AKT1 protein]; eupafolin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased phosphorylation of AKT1 protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of AKT1 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in decreased phosphorylation of AKT1 protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of AKT1 mRNA]; morin inhibits the reaction [Streptozocin results in increased expression of AKT1 mRNA]; myrtenal inhibits the reaction [Streptozocin results in decreased expression of AKT1 protein]; nerolidol inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased phosphorylation of AKT1 protein]; Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of AKT1 mRNA]; piperlongumine inhibits the reaction [Streptozocin results in decreased expression of AKT1 protein]; Plant Extracts inhibits the reaction [[Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in decreased phosphorylation of AKT1 protein]; Propofol promotes the reaction [Streptozocin results in decreased phosphorylation of AKT1 protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased phosphorylation of AKT1 protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of AKT1 mRNA]; Rivastigmine inhibits the reaction [Streptozocin results in decreased expression of AKT1 mRNA]; Streptozocin results in decreased expression of and results in decreased phosphorylation of AKT1 protein; STUB1 inhibits the reaction [Streptozocin results in decreased expression of AKT1 protein]; tin mesoporphyrin inhibits the reaction [[cobaltiprotoporphyrin co-treated with Streptozocin] results in increased phosphorylation of AKT1 protein]; Tribulus extract inhibits the reaction [Streptozocin results in decreased phosphorylation of AKT1 protein]; Wortmannin inhibits the reaction [Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of AKT1 mRNA]]
Streptozocin results in decreased expression of AKT1 mRNA; Streptozocin results in decreased expression of AKT1 protein
[Dietary Fats co-treated with Streptozocin] results in decreased expression of AKT1 mRNA; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of AKT1 protein; [Streptozocin co-treated with CNR1 protein] affects the phosphorylation of AKT1 protein; [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased phosphorylation of AKT1 protein; [Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of AKT1 protein; Metformin inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of AKT1 protein]; Metformin inhibits the reaction [Streptozocin results in decreased phosphorylation of AKT1 protein]; perilla seed oil inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of AKT1 protein]; phillyrin inhibits the reaction [Streptozocin results in decreased phosphorylation of AKT1 protein]
streptozocin increases phosphorylation of Akt1 protein in heart		 CTD
RGD		 PMID:16595661 PMID:19002579 PMID:22675305 PMID:24810525 PMID:25541178 More... RGD:156430337 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Akt2 AKT serine/threonine kinase 2 multiple interactions EXP [Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of AKT2 protein; Butyric Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of AKT2 protein]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of AKT2 protein] CTD PMID:27270450 NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817 		JBrowse link
G Alad aminolevulinate dehydratase multiple interactions ISO [Streptozocin results in increased abundance of Blood Glucose] which results in decreased expression of ALAD protein; alpha-Tocopherol inhibits the reaction [[Streptozocin results in increased abundance of Blood Glucose] which results in decreased expression of ALAD protein] CTD PMID:7728901 NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474 		JBrowse link
G Alas1 5'-aminolevulinate synthase 1 decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of ALAS1 mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in decreased expression of ALAS1 mRNA]		 CTD PMID:16684804 NCBI chr 8:106,876,514...106,889,917
Ensembl chr 8:106,876,514...106,889,917 		JBrowse link
G Alb albumin multiple interactions
increases secretion
decreases expression
increases expression		 ISO
EXP		 [Streptozocin co-treated with Dietary Fats co-treated with Carboxymethylcellulose Sodium] results in increased expression of ALB protein; AM6545 inhibits the reaction [Streptozocin results in increased expression of ALB protein]; naringenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Carboxymethylcellulose Sodium] results in increased expression of ALB protein]; Perindopril inhibits the reaction [Streptozocin results in increased expression of ALB protein]; TXN protein inhibits the reaction [Streptozocin results in increased secretion of ALB protein]
[bisphenol A co-treated with Streptozocin] results in decreased expression of ALB protein; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of ALB protein; [Streptozocin co-treated with Cadmium] results in increased expression of ALB protein; [Streptozocin co-treated with Cholesterol, Dietary] results in increased secretion of ALB protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of ALB protein; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of ALB protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of ALB protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of ALB protein]; Eugenol inhibits the reaction [Streptozocin results in decreased expression of ALB protein]; Gallic Acid inhibits the reaction [Streptozocin results in decreased expression of ALB protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Cholesterol, Dietary] results in increased secretion of ALB protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of ALB protein]; hesperetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of ALB protein]; LR-90 inhibits the reaction [Streptozocin results in increased expression of ALB protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of ALB protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of ALB protein]; Plant Extracts inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of ALB protein]; procyanidin B2 inhibits the reaction [Streptozocin results in increased expression of ALB protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of ALB protein]		 CTD PMID:12845431 PMID:14871415 PMID:17360766 PMID:18204486 PMID:21450970 More... NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression EXP Streptozocin results in increased expression of ALDH1A1 mRNA CTD PMID:25905778 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961 		JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of ALDH1A3 mRNA CTD PMID:33484791 NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member increases expression
decreases expression
multiple interactions		 EXP Streptozocin results in increased expression of ALDH2 protein
Streptozocin results in decreased expression of ALDH2 mRNA; Streptozocin results in decreased expression of ALDH2 protein
Ethanol inhibits the reaction [Streptozocin results in decreased expression of ALDH2]		 CTD PMID:21136691 PMID:23500772 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
G Aldob aldolase, fructose-bisphosphate B increases expression
multiple interactions		 EXP Streptozocin results in increased expression of ALDOB protein
Trientine inhibits the reaction [Streptozocin results in increased expression of ALDOB protein]		 CTD PMID:19634143 NCBI chr 5:63,889,045...63,902,086
Ensembl chr 5:63,889,046...63,902,116 		JBrowse link
G Alkbh3 alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of ALKBH3 mRNA CTD PMID:20665664 NCBI chr 3:79,939,515...79,972,820
Ensembl chr 3:79,939,600...79,972,000 		JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of ALOX5AP mRNA CTD PMID:29127188 NCBI chr12:5,748,941...5,772,986
Ensembl chr12:5,748,944...5,772,986 		JBrowse link
G Alpk1 alpha-kinase 1 multiple interactions
increases response to substance		 ISO [ALPK1 protein results in increased susceptibility to Streptozocin] which results in decreased expression of PRKG2 mRNA; [ALPK1 protein results in increased susceptibility to Streptozocin] which results in increased expression of TGFB1 mRNA; [ALPK1 protein results in increased susceptibility to Streptozocin] which results in increased expression of TGFB1 protein; ALPK1 protein promotes the reaction [Streptozocin results in decreased secretion of INS1 protein]; ALPK1 protein promotes the reaction [Streptozocin results in increased abundance of Blood Glucose] CTD PMID:27542954 NCBI chr 2:216,126,939...216,247,180
Ensembl chr 2:216,128,825...216,247,157 		JBrowse link
G Ambn ameloblastin multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of AMBN mRNA CTD PMID:33484791 NCBI chr14:19,601,761...19,614,382
Ensembl chr14:19,601,702...19,614,393 		JBrowse link
G Angpt1 angiopoietin 1 increases expression
decreases expression
multiple interactions		 EXP Streptozocin results in increased expression of ANGPT1 mRNA; Streptozocin results in increased expression of ANGPT1 protein
Streptozocin results in decreased expression of ANGPT1 mRNA
baicalin inhibits the reaction [Streptozocin results in decreased expression of ANGPT1 mRNA]		 CTD PMID:15643138 PMID:19958114 PMID:34414639 NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067 		JBrowse link
G Angpt2 angiopoietin 2 multiple interactions
increases expression		 EXP Enalapril inhibits the reaction [Streptozocin results in increased expression of ANGPT2 mRNA]; Simvastatin inhibits the reaction [Streptozocin results in increased expression of ANGPT2 protein]
Streptozocin results in increased expression of ANGPT2 mRNA; Streptozocin results in increased expression of ANGPT2 protein		 CTD PMID:15643138 PMID:19958114 PMID:20821229 NCBI chr16:71,088,364...71,138,805
Ensembl chr16:71,088,364...71,138,804 		JBrowse link
G Angptl4 angiopoietin-like 4 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of ANGPTL4 mRNA CTD PMID:25905778 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519 		JBrowse link
G Ankrd1 ankyrin repeat domain 1 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of ANKRD1 mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of ANKRD1 mRNA]		 CTD PMID:16684804 NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919 		JBrowse link
G Ankrd2 ankyrin repeat domain 2 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of ANKRD2 mRNA CTD PMID:33484791 NCBI chr 1:240,847,111...240,856,563
Ensembl chr 1:240,847,072...240,856,566 		JBrowse link
G Anpep alanyl aminopeptidase, membrane decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of ANPEP protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of ANPEP protein]		 CTD PMID:19634143 NCBI chr 1:133,767,332...133,810,137
Ensembl chr 1:133,767,332...133,785,789 		JBrowse link
G Anxa3 annexin A3 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of ANXA3 protein
[resveratrol co-treated with Streptozocin] results in increased expression of ANXA3 mRNA; Trientine inhibits the reaction [Streptozocin results in increased expression of ANXA3 protein]		 CTD PMID:21136691 PMID:25905778 NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617 		JBrowse link
G Anxa5 annexin A5 decreases expression
increases expression
multiple interactions		 EXP Streptozocin results in decreased expression of ANXA5 protein
Streptozocin results in increased expression of ANXA5 protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of ANXA5 protein]; Trientine inhibits the reaction [Streptozocin results in increased expression of ANXA5 protein]		 CTD PMID:19634143 PMID:21136691 NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369 		JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 increases response to substance ISO APEX1 protein mutant form results in increased susceptibility to Streptozocin CTD PMID:19470598 NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785 		JBrowse link
G Apoa1 apolipoprotein A1 multiple interactions
increases expression		 EXP Trientine inhibits the reaction [Streptozocin results in increased expression of APOA1 protein] CTD PMID:19634143 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035 		JBrowse link
G Apoa4 apolipoprotein A4 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of APOA4 mRNA CTD PMID:25905778 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469 		JBrowse link
G Apob apolipoprotein B multiple interactions EXP [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of APOB mRNA CTD PMID:35786680 NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497 		JBrowse link
G Apoe apolipoprotein E increases expression
multiple interactions		 EXP
ISO		 Streptozocin results in increased expression of APOE mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of APOE mRNA]
[Streptozocin co-treated with APOE mutant form] results in increased abundance of Glucosamine; INS1 inhibits the reaction [[Streptozocin co-treated with APOE mutant form] results in increased abundance of Glucosamine]		 CTD PMID:16380481 PMID:16684804 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G App amyloid beta precursor protein multiple interactions
increases expression		 EXP
ISO		 Memantine inhibits the reaction [Streptozocin results in increased expression of APP protein modified form]
Streptozocin results in increased expression of APP mRNA; Streptozocin results in increased expression of APP protein; Streptozocin results in increased expression of APP protein modified form
5-Methoxypsoralen inhibits the reaction [Streptozocin results in increased expression of APP protein modified form]; Alendronate inhibits the reaction [Streptozocin results in increased expression of APP protein]; Donepezil inhibits the reaction [Streptozocin results in increased expression of APP protein]; Tadalafil inhibits the reaction [Streptozocin results in increased expression of APP protein modified form]		 CTD PMID:21069392 PMID:21290839 PMID:30481507 PMID:34428446 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Aqp1 aquaporin 1 multiple interactions
decreases expression		 EXP Trientine inhibits the reaction [Streptozocin results in decreased expression of AQP1 protein] CTD PMID:19634143 NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690 		JBrowse link
G Aqp7 aquaporin 7 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of AQP7 mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of AQP7 mRNA]		 CTD PMID:16684804 NCBI chr 5:56,171,649...56,186,642
Ensembl chr 5:56,172,519...56,186,642 		JBrowse link
G Aqp9 aquaporin 9 increases expression EXP Streptozocin results in increased expression of AQP9 protein CTD PMID:22114114 NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395 		JBrowse link
G Arg1 arginase 1 multiple interactions
increases expression
decreases expression
increases activity		 ISO
EXP		 [NTN1 protein co-treated with Streptozocin] results in increased expression of ARG1 protein; AM6545 inhibits the reaction [Streptozocin results in decreased expression of ARG1 mRNA]; ARG1 gene mutant form inhibits the reaction [Streptozocin results in increased expression of GLB1 protein]; Perindopril inhibits the reaction [AM6545 inhibits the reaction [Streptozocin results in decreased expression of ARG1 mRNA]]
Streptozocin results in increased expression of ARG1 protein
Streptozocin results in increased activity of ARG1 protein		 CTD PMID:29059224 PMID:29673160 PMID:30184259 PMID:34039237 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422 		JBrowse link
G Arhgap9 Rho GTPase activating protein 9 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of ARHGAP9 mRNA CTD PMID:25905778 NCBI chr 7:63,148,573...63,157,025
Ensembl chr 7:63,148,900...63,157,524 		JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of ASNS mRNA CTD PMID:25905778 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423 		JBrowse link
G Atf2 activating transcription factor 2 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of ATF2 protein
resveratrol inhibits the reaction [Streptozocin results in increased expression of ATF2 protein]		 CTD PMID:26499206 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236 		JBrowse link
G Atf3 activating transcription factor 3 multiple interactions ISO [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of ATF3 mRNA]; [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of ATF3 protein]; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of ATF3 mRNA; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of ATF3 protein CTD PMID:38282657 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Atf4 activating transcription factor 4 multiple interactions
increases expression
increases phosphorylation		 ISO
EXP		 [Dietary Fats co-treated with Streptozocin] results in increased expression of ATF4 mRNA; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of ATF4 mRNA]; sulforaphane inhibits the reaction [Streptozocin results in increased expression of ATF4 protein]
Streptozocin results in increased phosphorylation of ATF4 protein
4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased phosphorylation of ATF4 protein]		 CTD PMID:24967692 PMID:30980806 PMID:33812996 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446 		JBrowse link
G Atf5 activating transcription factor 5 decreases expression EXP Streptozocin results in decreased expression of ATF5 mRNA CTD PMID:25905778 NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:95,295,610...95,299,707 		JBrowse link
G Atf6 activating transcription factor 6 increases cleavage
multiple interactions
increases expression 		EXP
ISO		 Streptozocin results in increased cleavage of ATF6 protein
4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased cleavage of ATF6 protein]; [Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of ATF6 protein; Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of ATF6 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of ATF6 protein]
[Dietary Fats co-treated with Streptozocin] results in increased expression of ATF6 mRNA; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of ATF6 mRNA]
streptozocin increases expression of Atf6 protein in heart		 CTD
RGD		 PMID:30980806 PMID:33812996 PMID:34801538 PMID:36044268 RGD:156430337 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177 		JBrowse link
G Atg12 autophagy related 12 increases expression ISO Streptozocin results in increased expression of ATG12 mRNA CTD PMID:24889822 NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418 		JBrowse link
G Atg5 autophagy related 5 increases expression
multiple interactions		 ISO
EXP		 Streptozocin results in increased expression of ATG5 mRNA
[[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in decreased expression of ATG5 mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of ATG5 mRNA
Streptozocin results in increased expression of ATG5 protein		 CTD PMID:24889822 PMID:35786680 PMID:38706688 NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209 		JBrowse link
G Atox1 antioxidant 1 copper chaperone decreases expression EXP Streptozocin results in decreased expression of ATOX1 protein CTD PMID:24927960 NCBI chr10:39,564,855...39,579,892
Ensembl chr10:39,564,857...39,579,950 		JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 decreases activity
multiple interactions
decreases expression		 EXP
ISO		 Streptozocin results in decreased activity of ATP2A2 protein
[bisphenol A co-treated with Streptozocin] results in decreased expression of ATP2A2 mRNA; [Ethinyl Estradiol co-treated with Streptozocin] results in decreased expression of ATP2A2 mRNA; [octylphenol co-treated with Streptozocin] results in decreased expression of ATP2A2 mRNA
Streptozocin results in decreased expression of ATP2A2 mRNA
Triterpenes inhibits the reaction [Streptozocin results in decreased expression of ATP2A2 mRNA]; Triterpenes inhibits the reaction [Streptozocin results in decreased expression of ATP2A2 protein]
Streptozocin results in decreased expression of ATP2A2 mRNA; Streptozocin results in decreased expression of ATP2A2 protein		 CTD PMID:16685413 PMID:19000375 PMID:29935216 NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101 		JBrowse link
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 multiple interactions ISO [Streptozocin co-treated with bisphenol A] results in decreased expression of ATP2A3 mRNA; [Streptozocin co-treated with octylphenol] results in decreased expression of ATP2A3 mRNA CTD PMID:29935216 NCBI chr10:57,581,742...57,612,758
Ensembl chr10:57,582,128...57,612,748 		JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 multiple interactions
increases expression		 ISO [Streptozocin co-treated with bisphenol A] results in increased expression of ATP2B1 mRNA; [Streptozocin co-treated with octylphenol] results in increased expression of ATP2B1 mRNA
Streptozocin results in increased expression of ATP2B1 mRNA		 CTD PMID:29935216 NCBI chr 7:33,735,595...33,845,226
Ensembl chr 7:33,735,871...33,843,295 		JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha increases expression
multiple interactions		 EXP Streptozocin results in increased expression of ATP5F1A protein
Trientine inhibits the reaction [Streptozocin results in increased expression of ATP5F1A protein]		 CTD PMID:21136691 NCBI chr18:71,292,406...71,300,342
Ensembl chr18:71,292,374...71,300,794 		JBrowse link
G Atp5f1b ATP synthase F1 subunit beta increases expression
multiple interactions		 EXP Streptozocin results in increased expression of ATP5F1B protein
Trientine inhibits the reaction [Streptozocin results in increased expression of ATP5F1B protein]		 CTD PMID:21136691 NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273 		JBrowse link
G Atp5mf ATP synthase membrane subunit f increases expression
multiple interactions
affects expression		 EXP
ISO		 Streptozocin results in increased expression of ATP5MF protein
Trientine inhibits the reaction [Streptozocin results in increased expression of ATP5MF protein]
Streptozocin affects the expression of ATP5MF mRNA		 CTD PMID:18583417 PMID:19634143 NCBI chr12:9,421,665...9,428,236
Ensembl chr12:9,421,579...9,428,236 		JBrowse link
G Atp5po ATP synthase peripheral stalk subunit OSCP increases expression
multiple interactions		 EXP Streptozocin results in increased expression of ATP5PO protein
Trientine inhibits the reaction [Streptozocin results in increased expression of ATP5PO protein]		 CTD PMID:19634143 NCBI chr11:31,165,218...31,171,530
Ensembl chr11:31,165,217...31,171,592 		JBrowse link
G Atp6ap2 ATPase H+ transporting accessory protein 2 multiple interactions
increases expression		 EXP (3,4-dihydroxyphenylamino)-2-imidazoline inhibits the reaction [Streptozocin results in increased expression of ATP6AP2 mRNA]; (3,4-dihydroxyphenylamino)-2-imidazoline inhibits the reaction [Streptozocin results in increased expression of ATP6AP2 protein]; Valsartan inhibits the reaction [Streptozocin results in increased expression of ATP6AP2 mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of ATP6AP2 protein]
Streptozocin results in increased expression of ATP6AP2 mRNA; Streptozocin results in increased expression of ATP6AP2 protein		 CTD PMID:18192338 NCBI chr  X:10,183,983...10,210,948
Ensembl chr  X:10,183,068...10,210,918 		JBrowse link
G Atp7a ATPase copper transporting alpha multiple interactions
decreases expression		 ISO ATP7A gene mutant form promotes the reaction [Streptozocin results in increased chemical synthesis of Superoxides]; ATP7A protein inhibits the reaction [Streptozocin results in increased chemical synthesis of Superoxides]; INS protein inhibits the reaction [Streptozocin results in decreased expression of ATP7A protein] CTD PMID:23884884 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354 		JBrowse link
G Atp7b ATPase copper transporting beta decreases expression EXP Streptozocin results in decreased expression of ATP7B protein CTD PMID:24927960 NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636 		JBrowse link
G Avp arginine vasopressin multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in increased expression of AVP mRNA; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in increased expression of AVP mRNA] CTD PMID:32303808 NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425 		JBrowse link
G Axl Axl receptor tyrosine kinase increases expression EXP Streptozocin results in increased expression of AXL protein CTD PMID:12644472 NCBI chr 1:81,265,088...81,296,278
Ensembl chr 1:81,265,088...81,296,265 		JBrowse link
G B2m beta-2 microglobulin increases expression
multiple interactions		 EXP
ISO		 Streptozocin results in increased expression of B2M protein
diphenyldiselenide inhibits the reaction [Streptozocin results in increased activity of B2M protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of B2M protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of B2M protein]
Metformin inhibits the reaction [Streptozocin results in increased expression of B2M protein]; phillyrin inhibits the reaction [Streptozocin results in increased expression of B2M protein]		 CTD PMID:33639173 PMID:34649470 NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766 		JBrowse link
G B3galnt1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of B3GALNT1 mRNA CTD PMID:25905778 NCBI chr 2:153,847,297...153,877,371
Ensembl chr 2:153,846,474...153,877,332 		JBrowse link
G Baat bile acid CoA:amino acid N-acyltransferase multiple interactions ISO [Dietary Fats co-treated with Streptozocin] results in decreased expression of BAAT mRNA CTD PMID:29382564 NCBI chr 5:63,851,668...63,860,641
Ensembl chr 5:63,850,705...63,860,685 		JBrowse link
G Bace1 beta-secretase 1 multiple interactions
increases expression		 ISO Alendronate inhibits the reaction [Streptozocin results in increased expression of BACE1 protein]; Donepezil inhibits the reaction [Streptozocin results in increased expression of BACE1 protein] CTD PMID:30481507 NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876 		JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions
decreases expression
increases expression		 EXP Anthocyanins inhibits the reaction [Streptozocin results in decreased expression of BAD protein modified form]; Anthocyanins inhibits the reaction [Streptozocin results in increased expression of BAD protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased expression of BAD protein]; Streptozocin results in increased phosphorylation of and results in decreased activity of BAD protein
Streptozocin results in decreased expression of BAD protein; Streptozocin results in decreased expression of BAD protein modified form		 CTD PMID:15976052 PMID:19682444 PMID:28856781 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions
increases expression		 EXP Anthocyanins inhibits the reaction [Streptozocin results in increased expression of BAK1 protein] CTD PMID:28856781 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
affects expression		 ISO
EXP		 [Streptozocin co-treated with Dietary Fats] results in increased expression of BAX mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of BAX protein; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of BAX protein]; IGF1 protein inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of BAX protein]; montelukast inhibits the reaction [Streptozocin results in increased expression of BAX protein]; phillyrin inhibits the reaction [Streptozocin results in increased expression of BAX protein]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of BAX mRNA]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of BAX protein]; sulforaphane inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Valsartan inhibits the reaction [Streptozocin results in increased expression of BAX protein]
Streptozocin results in increased expression of BAX; Streptozocin results in increased expression of BAX mRNA; Streptozocin results in increased expression of BAX protein
2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Calcitriol inhibits the reaction [Streptozocin results in increased expression of BAX protein]]; 2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BAX protein]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Streptozocin results in increased expression of BAX protein]; 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of BAX protein]; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of BAX protein; [Streptozocin co-treated with Isoproterenol] affects the expression of BAX protein; Angiotensin-Converting Enzyme Inhibitors inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Ascorbic Acid inhibits the reaction [Streptozocin results in increased expression of BAX protein]; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of BAX protein]; Calcitriol inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Curcumin inhibits the reaction [Streptozocin affects the expression of BAX protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; Diazoxide inhibits the reaction [Streptozocin results in increased expression of BAX protein]; fasudil inhibits the reaction [Streptozocin results in increased expression of BAX protein]; ferulic acid inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of BAX protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Hesperidin inhibits the reaction [2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BAX protein]]; Hesperidin inhibits the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BAX protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; Metformin inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; morin inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; Organoselenium Compounds inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Pentoxifylline inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Phosphocreatine inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Phycocyanin inhibits the reaction [Streptozocin results in increased expression of BAX protein]; piperlongumine inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of BAX]; Rivastigmine inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Sildenafil Citrate inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; Sildenafil Citrate promotes the reaction [Tadalafil inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]]; Streptozocin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of BAX protein]; Tadalafil inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; Tadalafil promotes the reaction [Sildenafil Citrate inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]]; Testosterone inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; Testosterone promotes the reaction [Sildenafil Citrate inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]]; Testosterone promotes the reaction [Sildenafil Citrate promotes the reaction [Tadalafil inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]]]; Testosterone promotes the reaction [Tadalafil inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]]; Testosterone promotes the reaction [Tadalafil promotes the reaction [Sildenafil Citrate inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]]]; Wortmannin inhibits the reaction [Phycocyanin inhibits the reaction [Streptozocin results in increased expression of BAX protein]]; Zinc inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; Zinc inhibits the reaction [Streptozocin results in increased expression of BAX protein]		 CTD PMID:11375343 PMID:18758938 PMID:19931367 PMID:20574430 PMID:20650802 More... NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Baz1b bromodomain adjacent to zinc finger domain, 1B affects expression ISO Streptozocin affects the expression of BAZ1B mRNA CTD PMID:26073000 NCBI chr12:21,431,985...21,489,956
Ensembl chr12:21,431,985...21,490,426 		JBrowse link
G Bbox1 gamma-butyrobetaine hydroxylase 1 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of BBOX1 mRNA CTD PMID:25905778 NCBI chr 3:96,822,654...96,871,786
Ensembl chr 3:96,822,655...96,871,458 		JBrowse link
G Bche butyrylcholinesterase multiple interactions
increases activity		 ISO Acetylcysteine inhibits the reaction [Streptozocin results in increased activity of BCHE protein] CTD PMID:27087133 PMID:30481507 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148 		JBrowse link
G Bckdha branched chain keto acid dehydrogenase E1 subunit alpha affects expression ISO Streptozocin affects the expression of BCKDHA mRNA CTD PMID:18583417 NCBI chr 1:81,138,946...81,167,765
Ensembl chr 1:81,138,947...81,167,862 		JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression
decreases expression
multiple interactions
affects expression		 EXP
ISO		 Streptozocin results in increased expression of BCL2 protein
Streptozocin results in decreased expression of BCL2 mRNA; Streptozocin results in decreased expression of BCL2 protein
[Diethylhexyl Phthalate co-treated with Streptozocin co-treated with Dietary Fats] results in decreased expression of BCL2 protein; [Streptozocin co-treated with arachidonyl-2-chloroethylamide] results in increased expression of BCL2 protein; [Streptozocin co-treated with bisphenol A] results in increased expression of BCL2 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of BCL2 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of BCL2 protein; [Streptozocin co-treated with Ethinyl Estradiol] results in increased expression of BCL2 mRNA; [Streptozocin co-treated with octylphenol] results in increased expression of BCL2 mRNA; AM 251 inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; bisphenol A promotes the reaction [Streptozocin results in decreased expression of BCL2 protein]; CEBPB protein inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; CNR1 protein promotes the reaction [Streptozocin results in decreased expression of BCL2 protein]; Ethinyl Estradiol promotes the reaction [Streptozocin results in decreased expression of BCL2 protein]; Metformin inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; montelukast inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; octylphenol promotes the reaction [Streptozocin results in decreased expression of BCL2 protein]; phillyrin inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of BCL2 mRNA]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of BCL2 protein]; Streptozocin inhibits the reaction [Cisplatin results in increased expression of BCL2 protein]; Valsartan inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]
2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Calcitriol inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]]; 2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BCL2 protein]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of BCL2 protein; [Rolipram co-treated with Pentoxifylline] inhibits the reaction [Streptozocin results in increased expression of BCL2 protein]; [Streptozocin co-treated with Arsenic] results in decreased expression of BCL2 mRNA; [Streptozocin co-treated with Cadmium] results in decreased expression of BCL2 mRNA; [Streptozocin co-treated with Isoproterenol] affects the expression of BCL2 protein; [Streptozocin co-treated with Lead co-treated with Manganese co-treated with Cadmium co-treated with Arsenic] results in decreased expression of BCL2 mRNA; [Streptozocin co-treated with Lead] results in decreased expression of BCL2 mRNA; [Streptozocin co-treated with Manganese] results in decreased expression of BCL2 mRNA; Angiotensin-Converting Enzyme Inhibitors inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Anthocyanins inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased expression of BCL2 protein]; Ascorbic Acid inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of BCL2 protein]; Calcitriol inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Curcumin inhibits the reaction [Streptozocin affects the expression of BCL2 protein]; dapagliflozin inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]; Diazoxide inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; fasudil inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of BCL2 protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Hesperidin inhibits the reaction [2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BCL2 protein]]; Hesperidin inhibits the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BCL2 protein]; IGF2R protein modified form promotes the reaction [Streptozocin results in decreased expression of BCL2 protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of BCL2 mRNA]; morin inhibits the reaction [Streptozocin results in increased expression of BCL2 mRNA]; Organoselenium Compounds inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Pentoxifylline inhibits the reaction [Streptozocin results in increased expression of BCL2 protein]; Phosphocreatine inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; piperlongumine inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Propofol inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Rivastigmine inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Sildenafil Citrate inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]; Sildenafil Citrate promotes the reaction [Tadalafil inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]]; Streptozocin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased expression of BCL2 protein]; Streptozocin promotes the reaction [IGF2R protein modified form results in decreased expression of BCL2 protein modified form]; Tadalafil inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]; Tadalafil promotes the reaction [Sildenafil Citrate inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]]; Testosterone inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]; Testosterone promotes the reaction [Sildenafil Citrate inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]]; Testosterone promotes the reaction [Sildenafil Citrate promotes the reaction [Tadalafil inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]]]; Testosterone promotes the reaction [Tadalafil inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]]; Testosterone promotes the reaction [Tadalafil promotes the reaction [Sildenafil Citrate inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]]]; Zinc inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]; Zinc inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]		 CTD PMID:15056984 PMID:15587404 PMID:15976052 PMID:16909474 PMID:18758938 More... NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2a1 BCL2-related protein A1 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of BCL2A1 mRNA CTD PMID:25905778 NCBI chr 8:89,716,914...89,724,998
Ensembl chr 8:89,716,914...89,724,998 		JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression
multiple interactions
decreases expression		 EXP
ISO		 Streptozocin results in increased expression of BCL2L1 protein
Anthocyanins inhibits the reaction [Streptozocin results in decreased expression of BCL2L1 protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased expression of BCL2L1 protein]; Ascorbic Acid inhibits the reaction [Streptozocin results in decreased expression of BCL2L1 protein]; cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of BCL2L1 protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of BCL2L1 mRNA]; morin inhibits the reaction [Streptozocin results in increased expression of BCL2L1 mRNA]; tin mesoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of BCL2L1 protein]]
Streptozocin results in decreased expression of BCL2L1 mRNA; Streptozocin results in decreased expression of BCL2L1 protein		 CTD PMID:15976052 PMID:16595661 PMID:18758938 PMID:19682444 PMID:24781736 More... NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Bcl2l11 Bcl2-like 11 increases expression
multiple interactions		 ISO Streptozocin results in increased expression of BCL2L11 mRNA
Chlorpyrifos promotes the reaction [Streptozocin results in increased expression of BCL2L11 mRNA]		 CTD PMID:33524429 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068 		JBrowse link
G Bcl3 BCL3, transcription coactivator multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of BCL3 mRNA CTD PMID:25905778 NCBI chr 1:79,471,368...79,485,908
Ensembl chr 1:79,471,369...79,485,607 		JBrowse link
G Bdh1 3-hydroxybutyrate dehydrogenase 1 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of BDH1 mRNA CTD PMID:25905778 NCBI chr11:69,302,534...69,343,173
Ensembl chr11:69,302,534...69,337,671 		JBrowse link
G Bdkrb1 bradykinin receptor B1 increases expression
multiple interactions		 ISO
EXP		 Streptozocin results in increased expression of BDKRB1 mRNA
[HOE 140, desArg(10)- binds to and results in decreased activity of BDKRB1 protein] which results in decreased susceptibility to Streptozocin		 CTD PMID:17989505 PMID:19516248 NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747 		JBrowse link
G Bdkrb2 bradykinin receptor B2 increases expression
multiple interactions		 ISO
EXP		 Streptozocin results in increased expression of BDKRB2 mRNA
[icatibant binds to and results in decreased activity of BDKRB2 protein] which results in decreased susceptibility to Streptozocin		 CTD PMID:17989505 PMID:19516248 NCBI chr 6:124,472,317...124,502,497
Ensembl chr 6:124,472,566...124,502,497 		JBrowse link
G Bdnf brain-derived neurotrophic factor decreases expression
multiple interactions		 EXP
ISO		 Streptozocin results in decreased expression of BDNF mRNA; Streptozocin results in decreased expression of BDNF protein
Metformin inhibits the reaction [Streptozocin results in increased expression of BDNF mRNA]; morin inhibits the reaction [Streptozocin results in increased expression of BDNF mRNA]; Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of BDNF protein]; Rivastigmine inhibits the reaction [Streptozocin results in decreased expression of BDNF protein]; Vitamin B 12 inhibits the reaction [Streptozocin results in decreased expression of BDNF protein]; Wortmannin inhibits the reaction [Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of BDNF protein]]
5-Methoxypsoralen inhibits the reaction [Streptozocin results in decreased expression of BDNF protein]; Tadalafil inhibits the reaction [Streptozocin results in decreased expression of BDNF protein]		 CTD PMID:32805344 PMID:34428446 PMID:35414346 PMID:38049026 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Becn1 beclin 1 increases expression
multiple interactions
decreases expression		 ISO
EXP		 Streptozocin results in increased expression of BECN1 mRNA; Streptozocin results in increased expression of BECN1 protein
5-Methoxypsoralen inhibits the reaction [Streptozocin results in decreased expression of BECN1 protein modified form]; HU 308 inhibits the reaction [Streptozocin results in decreased expression of BECN1 protein]; Tadalafil inhibits the reaction [Streptozocin results in decreased expression of BECN1 protein modified form]
Streptozocin results in decreased expression of BECN1 protein; Streptozocin results in decreased expression of BECN1 protein modified form
[[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of BECN1 mRNA; dapagliflozin affects the reaction [Streptozocin results in decreased expression of BECN1 mRNA]		 CTD PMID:24889822 PMID:30459625 PMID:34428446 PMID:35786680 PMID:37352119 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Bglap bone gamma-carboxyglutamate protein decreases expression
multiple interactions		 EXP
ISO		 Streptozocin results in decreased expression of BGLAP mRNA; Streptozocin results in decreased expression of BGLAP protein
[Dietary Fats co-treated with Streptozocin] results in decreased expression of BGLAP protein modified form; Warfarin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of BGLAP protein modified form]
[Streptozocin co-treated with Dietary Fats] results in decreased expression of BGLAP protein; Calcitriol inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of BGLAP protein]		 CTD PMID:25617479 PMID:27488359 PMID:33450223 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495 		JBrowse link
G Bhmt betaine-homocysteine S-methyltransferase increases activity
increases expression
multiple interactions		 EXP
ISO		 Streptozocin results in increased activity of BHMT protein
Streptozocin results in increased expression of BHMT mRNA
[Streptozocin co-treated with Dietary Fats] affects the expression of BHMT mRNA		 CTD PMID:16835399 PMID:29127188 NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742 		JBrowse link
G Bmal1 basic helix-loop-helix ARNT like 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of BMAL1 mRNA CTD PMID:29127188 NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231 		JBrowse link
G Bmp6 bone morphogenetic protein 6 decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of BMP6 mRNA
esculetin inhibits the reaction [Streptozocin results in decreased expression of BMP6 mRNA]		 CTD PMID:21450970 NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365 		JBrowse link
G Bmp7 bone morphogenetic protein 7 increases expression
affects expression		 EXP Streptozocin results in increased expression of BMP7 protein
Streptozocin affects the expression of BMP7 mRNA		 CTD PMID:17437042 NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788 		JBrowse link
G C1qa complement C1q A chain multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of C1QA mRNA CTD PMID:25905778 NCBI chr 5:149,133,635...149,136,482
Ensembl chr 5:149,133,636...149,136,534 		JBrowse link
G C1qb complement C1q B chain increases expression
multiple interactions		 EXP Streptozocin results in increased expression of C1QB mRNA
[resveratrol co-treated with Streptozocin] results in increased expression of C1QB mRNA; vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of C1QB mRNA]		 CTD PMID:16684804 PMID:25905778 NCBI chr 5:149,118,843...149,124,394
Ensembl chr 5:149,118,846...149,124,407 		JBrowse link
G C1qc complement C1q C chain multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of C1QC mRNA CTD PMID:25905778 NCBI chr 5:149,127,412...149,130,757
Ensembl chr 5:149,127,415...149,131,017 		JBrowse link
G C4b complement C4B increases expression
multiple interactions		 EXP Streptozocin results in increased expression of C4B mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of C4B mRNA]		 CTD PMID:16684804 NCBI chr20:4,197,371...4,211,684
Ensembl chr20:4,197,366...4,211,681 		JBrowse link
G Cacna1b calcium voltage-gated channel subunit alpha1 B multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of CACNA1B mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CACNA1B mRNA] CTD PMID:33484791 NCBI chr 3:7,380,892...7,546,104
Ensembl chr 3:7,380,922...7,546,091 		JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C multiple interactions
increases expression		 ISO [bisphenol A co-treated with Streptozocin] results in decreased expression of CACNA1C mRNA; [octylphenol co-treated with Streptozocin] results in decreased expression of CACNA1C mRNA
Streptozocin results in increased expression of CACNA1C mRNA		 CTD PMID:29935216 NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648 		JBrowse link
G Cacna1s calcium voltage-gated channel subunit alpha1 S multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of CACNA1S mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CACNA1S mRNA] CTD PMID:33484791 NCBI chr13:47,493,949...47,564,194
Ensembl chr13:47,493,949...47,564,318 		JBrowse link
G Calca calcitonin-related polypeptide alpha decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of CALCA protein
Botulinum Toxins, Type A inhibits the reaction [Streptozocin results in decreased expression of CALCA protein]; capsazepine inhibits the reaction [Streptozocin results in decreased expression of CALCA protein]; RN 1734 inhibits the reaction [Streptozocin results in decreased expression of CALCA protein]; U 0126 inhibits the reaction [Streptozocin results in decreased expression of CALCA protein]		 CTD PMID:30583000 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105 		JBrowse link
G Calm1 calmodulin 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in increased expression of CALM1 protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in increased expression of CALM1 protein] CTD PMID:32303808 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227 		JBrowse link
G Calm3 calmodulin 3 decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of CALM3 protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of CALM3 protein]		 CTD PMID:19634143 NCBI chr 1:77,590,668...77,597,776
Ensembl chr 1:77,589,230...77,592,207 		JBrowse link
G Calr calreticulin decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of CALR protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of CALR protein]		 CTD PMID:19634143 NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414 		JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha multiple interactions
decreases expression		 ISO
EXP		 myristoylated autocamtide-2-related inhibitory peptide inhibits the reaction [Streptozocin results in increased phosphorylation of CAMK2A protein]; resveratrol inhibits the reaction [Streptozocin results in increased expression of and results in increased phosphorylation of and results in increased activity of CAMK2A protein]; Streptozocin results in increased expression of and results in increased phosphorylation of and results in increased activity of CAMK2A protein
Ibuprofen inhibits the reaction [Streptozocin results in decreased expression of CAMK2A mRNA]; Ibuprofen inhibits the reaction [Streptozocin results in decreased expression of CAMK2A protein]; Memantine inhibits the reaction [Streptozocin results in decreased expression of CAMK2A mRNA]; Memantine inhibits the reaction [Streptozocin results in decreased expression of CAMK2A protein]
Streptozocin results in decreased expression of CAMK2A mRNA; Streptozocin results in decreased expression of CAMK2A protein		 CTD PMID:20424226 PMID:24333387 NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994 		JBrowse link
G Camp cathelicidin antimicrobial peptide multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of CAMP mRNA CTD PMID:33484791 NCBI chr 8:109,841,729...109,843,543
Ensembl chr 8:109,841,729...109,843,543 		JBrowse link
G Canx calnexin multiple interactions EXP [Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of CANX protein; Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of CANX protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of CANX protein] CTD PMID:34801538 NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821 		JBrowse link
G Capg capping actin protein, gelsolin like multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of CAPG mRNA CTD PMID:25905778 NCBI chr 4:104,594,743...104,611,856
Ensembl chr 4:104,594,753...104,611,856 		JBrowse link
G Capn8 calpain 8 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of CAPN8 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CAPN8 mRNA] CTD PMID:33484791 NCBI chr13:94,252,218...94,316,146
Ensembl chr13:94,253,054...94,316,146 		JBrowse link
G Car3 carbonic anhydrase 3 multiple interactions
decreases expression		 EXP [resveratrol co-treated with Streptozocin] results in decreased expression of CAR3 mRNA
Streptozocin results in decreased expression of CAR3 mRNA		 CTD PMID:25905778 NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280 		JBrowse link
G Cartpt CART prepropeptide decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of CARTPT mRNA
GHRL protein promotes the reaction [Streptozocin results in decreased expression of CARTPT mRNA]		 CTD PMID:20219977 NCBI chr 2:31,255,098...31,257,452
Ensembl chr 2:31,255,098...31,290,713 		JBrowse link
G Casp1 caspase 1 multiple interactions
increases expression		 EXP
ISO		 [Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased cleavage of CASP1 protein]; [Streptozocin co-treated with Dietary Fats] results in increased cleavage of CASP1 protein; Allopurinol inhibits the reaction [Streptozocin results in increased expression of CASP1 mRNA]; Allopurinol inhibits the reaction [Streptozocin results in increased expression of CASP1 protein]; Dimethyl Fumarate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased cleavage of CASP1 protein]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased cleavage of CASP1 protein]; Insulin promotes the reaction [Ozone inhibits the reaction [Streptozocin results in increased expression of CASP1 mRNA]]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased cleavage of CASP1 protein]; Ozone inhibits the reaction [Streptozocin results in increased expression of CASP1 mRNA]; palbinone inhibits the reaction [Streptozocin results in increased expression of and results in increased cleavage of CASP1 protein]; Quercetin inhibits the reaction [Streptozocin results in increased expression of CASP1 mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of CASP1 protein]; scutellarin inhibits the reaction [Streptozocin results in increased expression of CASP1 mRNA]; Streptozocin results in increased expression of and results in increased cleavage of CASP1 protein
Streptozocin results in increased expression of CASP1 mRNA; Streptozocin results in increased expression of CASP1 protein
[aucubin co-treated with Streptozocin co-treated with Dietary Fats] results in decreased cleavage of CASP1 protein; [Dietary Fats co-treated with Streptozocin] results in increased expression of CASP1 protein; [Streptozocin co-treated with Dextran Sulfate] results in increased cleavage of CASP1 protein; [Streptozocin co-treated with Dietary Fats] results in increased activity of CASP1 protein; GSDMD protein affects the reaction [Streptozocin results in increased cleavage of CASP1 protein]; loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CASP1 protein]; NLRP3 protein promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased activity of CASP1 protein]; Streptozocin results in increased expression of and results in increased cleavage of CASP1 protein		 CTD PMID:23647015 PMID:26614261 PMID:27783111 PMID:32202043 PMID:34212273 More... NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Casp12 caspase 12 increases expression
increases cleavage
multiple interactions		 ISO
EXP		 Streptozocin results in increased expression of CASP12 protein modified form
Streptozocin results in increased cleavage of CASP12 protein
FGF21 protein affects the reaction [Streptozocin results in increased expression of CASP12 protein modified form]; sulforaphane inhibits the reaction [Streptozocin results in increased cleavage of CASP12 protein]
Curcumin inhibits the reaction [Streptozocin results in increased cleavage of CASP12 protein]		 CTD PMID:23499715 PMID:24967692 PMID:25541178 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
decreases cleavage
increases cleavage
increases expression
decreases expression		 EXP
ISO		 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of CASP3 protein; [Rolipram co-treated with Pentoxifylline] inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; [Streptozocin co-treated with Arsenic] results in increased expression of CASP3 mRNA; [Streptozocin co-treated with Cadmium] results in increased expression of CASP3 mRNA; [Streptozocin co-treated with IGF2R protein modified form] results in increased expression of CASP3 protein modified form; [Streptozocin co-treated with Lead co-treated with Manganese co-treated with Cadmium co-treated with Arsenic] results in increased expression of CASP3 mRNA; [Streptozocin co-treated with Lead] results in increased expression of CASP3 mRNA; [Streptozocin co-treated with Manganese] results in increased expression of CASP3 mRNA; Acetylcysteine inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; Anthocyanins inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of CASP3 protein]; Curcumin inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; diallyl trisulfide inhibits the reaction [Streptozocin results in decreased cleavage of CASP3 protein]; Ellagic Acid inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; Ellagic Acid promotes the reaction [sinapinic acid inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]]; ferulic acid analog inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of CASP3 protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; Ibuprofen inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; Ibuprofen inhibits the reaction [Streptozocin results in increased expression of CASP3 mRNA]; Imatinib Mesylate inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; Insulin promotes the reaction [Ozone inhibits the reaction [Streptozocin results in increased expression of CASP3 mRNA]]; Memantine inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; Memantine inhibits the reaction [Streptozocin results in increased expression of CASP3 mRNA]; Metformin inhibits the reaction [Streptozocin results in increased expression of CASP3 mRNA]; morin inhibits the reaction [Streptozocin results in increased expression of CASP3 mRNA]; nifuroxazide inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; nifuroxazide inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Ozone inhibits the reaction [Streptozocin results in increased expression of CASP3 mRNA]; Pentoxifylline inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Phosphocreatine inhibits the reaction [Streptozocin results in decreased expression of CASP3 protein]; Phosphocreatine inhibits the reaction [Streptozocin results in increased expression of CASP3 protein modified form]; Propofol inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Rivastigmine inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; Rolipram inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Rosiglitazone inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; sinapinic acid inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; sinapinic acid promotes the reaction [Ellagic Acid inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]]; Streptozocin results in increased expression of and results in increased cleavage of CASP3 protein; Thioctic Acid inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; Tropisetron inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; Vitamin B 12 inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]
Streptozocin analog results in increased activity of CASP3 protein; Streptozocin results in increased activity of CASP3 protein
[Streptozocin co-treated with bisphenol A] results in increased expression of CASP3 mRNA; [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] affects the cleavage of CASP3 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of CASP3 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of CASP3 protein; [Streptozocin co-treated with NQO1 protein mutant form] results in increased expression of CASP3 protein modified form; [Streptozocin co-treated with octylphenol] results in increased expression of CASP3 mRNA; fatostatin promotes the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Metformin inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; montelukast inhibits the reaction [Streptozocin results in increased expression of CASP3 protein modified form]; NTN1 protein inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; phillyrin inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Quercetin inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CASP3 mRNA]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CASP3 protein]; Streptozocin inhibits the reaction [Cisplatin results in increased expression of CASP3 protein]; Streptozocin inhibits the reaction [Ethinyl Estradiol results in decreased expression of CASP3 mRNA]; sulforaphane inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]
Streptozocin results in increased expression of CASP3 mRNA; Streptozocin results in increased expression of CASP3 protein; Streptozocin results in increased expression of CASP3 protein modified form
Streptozocin results in increased expression of CASP3 mRNA; Streptozocin results in increased expression of CASP3 protein modified form
Streptozocin results in decreased expression of CASP3 mRNA; Streptozocin results in decreased expression of CASP3 protein		 CTD PMID:12502508 PMID:15976052 PMID:18721751 PMID:18758938 PMID:19133311 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp4 caspase 4 increases expression ISO Streptozocin results in increased expression of CASP4 mRNA CTD PMID:34212273 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092 		JBrowse link
G Casp6 caspase 6 increases expression EXP Streptozocin results in increased expression of CASP6 protein CTD PMID:15976052 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502 		JBrowse link
G Casp7 caspase 7 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of CASP7 protein
[Streptozocin co-treated with Fructose] results in increased expression of CASP7 protein; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of CASP7 protein]; dapagliflozin promotes the reaction [Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of CASP7 protein]]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of CASP7 protein]; Metformin promotes the reaction [dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of CASP7 protein]]		 CTD PMID:15976052 PMID:30551545 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729 		JBrowse link
G Casp8 caspase 8 multiple interactions
increases expression
increases cleavage
increases activity		 EXP Anthocyanins inhibits the reaction [Streptozocin results in increased expression of CASP8 protein]; Curcumin inhibits the reaction [Streptozocin results in increased cleavage of CASP8 protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of CASP8 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of CASP8 mRNA]; nifuroxazide inhibits the reaction [Streptozocin results in increased activity of CASP8 protein]
Streptozocin results in increased expression of CASP8 mRNA; Streptozocin results in increased expression of CASP8 protein		 CTD PMID:23267840 PMID:25541178 PMID:28856781 PMID:29606028 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 multiple interactions
increases expression
increases activity
decreases expression		 EXP
ISO		 [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of CASP9 protein; Anthocyanins inhibits the reaction [Streptozocin results in increased expression of CASP9 protein]; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of CASP9 protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of CASP9 protein]; IGF2R protein modified form inhibits the reaction [Streptozocin results in increased expression of CASP9 protein]; Insulin promotes the reaction [Ozone inhibits the reaction [Streptozocin results in increased expression of CASP9 mRNA]]; nifuroxazide inhibits the reaction [Streptozocin results in increased activity of CASP9 protein]; Ozone inhibits the reaction [Streptozocin results in increased expression of CASP9 mRNA]; Phosphocreatine inhibits the reaction [Streptozocin results in decreased expression of CASP9 protein]; Streptozocin results in increased expression of and results in increased cleavage of CASP9 protein; Thioctic Acid inhibits the reaction [Streptozocin results in increased expression of CASP9 protein]
Streptozocin results in increased expression of CASP9 mRNA; Streptozocin results in increased expression of CASP9 protein
[Streptozocin co-treated with Dietary Fats] results in increased expression of CASP9 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of CASP9 protein; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CASP9 mRNA]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CASP9 protein]		 CTD PMID:15976052 PMID:19951573 PMID:22940631 PMID:26614261 PMID:28856781 More... NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cat catalase increases expression
multiple interactions
decreases response to substance
increases phosphorylation
decreases expression
increases activity
decreases activity		 ISO
EXP		 Streptozocin results in increased expression of CAT mRNA
Streptozocin results in increased expression of CAT protein
CAT protein promotes the reaction [SOD2 protein results in decreased susceptibility to Streptozocin]; SOD2 protein promotes the reaction [CAT protein results in decreased susceptibility to Streptozocin]
Streptozocin results in increased phosphorylation of CAT protein
Streptozocin results in decreased expression of CAT; Streptozocin results in decreased expression of CAT mRNA
2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; [Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein; [Dietary Fats co-treated with Streptozocin] results in decreased expression of CAT mRNA; [Streptozocin co-treated with Dextran Sulfate] results in decreased expression of CAT protein; [Streptozocin co-treated with Dietary Fats] results in decreased activity of CAT protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein; [Streptozocin co-treated with INS1 protein co-treated with Glutathione] affects the expression of CAT mRNA; [Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein; Acrylamide promotes the reaction [Streptozocin results in decreased activity of CAT protein]; Alendronate inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein]; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein]; Donepezil inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; pterostilbene inhibits the reaction [Streptozocin results in decreased expression of CAT]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; rhodioloside inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of CAT mRNA]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of CAT protein]
Streptozocin results in decreased expression of CAT mRNA; Streptozocin results in decreased expression of CAT protein
1,3-dimethoxy-5-methyl-2-(3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl)benzene inhibits the reaction [4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in increased expression of CAT protein]]; 2-hydroxy-4-methoxy benzoic acid inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; 4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in increased expression of CAT protein]; 4-methyl-2-((2-methylbenzyl) amino)-1,3-thiazole-5-carboxylic acid inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; 5,3'-dihydroxy-3,6,7,4',5'-pentamethoxyflavone inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; [Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein; [Dietary Fats co-treated with Streptozocin] results in decreased expression of CAT protein; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein; [Fructose co-treated with Streptozocin] results in decreased activity of CAT protein; [Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein]; [Niacinamide co-treated with Streptozocin] results in decreased activity of CAT protein; [Phytic Acid co-treated with Inositol] inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; [pimagedine co-treated with Fatty Acids, Omega-3] inhibits the reaction [Streptozocin results in increased activity of CAT protein]; [Propolis co-treated with Chlorpyrifos co-treated with Streptozocin] results in increased activity of CAT protein; [Propolis co-treated with Streptozocin] results in increased activity of CAT protein; [Quercetin co-treated with coenzyme Q10] inhibits the reaction [Streptozocin results in increased activity of CAT protein]; [Quercetin co-treated with Streptozocin] results in increased activity of CAT protein; [Rosiglitazone co-treated with Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein; [Streptozocin co-treated with bisphenol A] results in decreased expression of CAT protein; [Streptozocin co-treated with Chlorpyrifos] results in increased activity of CAT protein; [Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the activity of CAT protein; [Streptozocin co-treated with Dietary Fats] results in decreased activity of CAT protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein; [Streptozocin co-treated with Isoproterenol] affects the activity of CAT protein; [Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of CAT protein; [Zinc Sulfate results in increased abundance of Zinc] inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; allyl methyl sulfide inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; alpha-Tocopherol inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; arjunolic acid inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; asiatic acid inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Berberine affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the activity of CAT protein]; Bezafibrate inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein]; caryophyllene inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; CAT protein inhibits the reaction [Streptozocin results in increased expression of GNA11 protein]; CAT protein inhibits the reaction [Streptozocin results in increased expression of GNAQ protein]; CAT protein inhibits the reaction [Streptozocin results in increased expression of PLCB1 protein]; CAT protein inhibits the reaction [Streptozocin results in increased expression of PLCB2 protein]; Chlorpyrifos promotes the reaction [Streptozocin results in increased activity of CAT protein]; Chromium inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; chromium tripicolinate inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; corilagin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; coumarin inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in decreased activity of CAT protein]; crocin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; dapagliflozin inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; Diltiazem inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Dimethyl Fumarate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein]; Diosmin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of CAT mRNA]; Ellagic Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein]; eupafolin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of CAT protein]; fenugreek seed meal inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Ficusin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased activity of CAT protein]; Gallic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased activity of CAT protein]; Gallic Acid inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; geraniol inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Gliclazide inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in decreased activity of CAT protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; Gliclazide inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein]; Glyburide inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; hesperetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein]; Imatinib Mesylate inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Imipramine inhibits the reaction [Streptozocin results in increased activity of CAT protein]; INS1 protein inhibits the reaction [Streptozocin results in increased activity of CAT protein]; isoquercitrin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Losartan inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; mangiferin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Melatonin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Metformin inhibits the reaction [[Fructose co-treated with Streptozocin] results in decreased activity of CAT protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein]; Metformin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Metformin inhibits the reaction [Streptozocin results in decreased expression of CAT mRNA]; morin analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased activity of CAT protein]; morin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; myrsinoic acid B inhibits the reaction [Streptozocin results in increased activity of CAT protein]; myrtenol inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; naringenin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; nerolidol inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein]; notoginsenoside R1 inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; palbinone inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; pinitol inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Pioglitazone inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased activity of CAT protein]; Pioglitazone inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; Pioglitazone inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; piperlongumine inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; Plant Extracts inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein]; Propolis inhibits the reaction [[Streptozocin co-treated with Chlorpyrifos] results in increased activity of CAT protein]; Propolis inhibits the reaction [Streptozocin results in increased activity of CAT protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of CAT protein]; Quercetin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Quercetin inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; Quercetin inhibits the reaction [Streptozocin results in increased activity of CAT protein]; Resveratrol inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in decreased activity of CAT protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of and results in decreased activity of CAT protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of CAT mRNA]; Resveratrol promotes the reaction [Streptozocin results in decreased expression of CAT mRNA]; rhapontin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Rosiglitazone affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the activity of CAT protein]; S-allylcysteine inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; Saponins inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; sodium arsenate promotes the reaction [Streptozocin results in decreased activity of CAT protein]; Sodium Selenite inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Streptozocin inhibits the reaction [Lipopolysaccharides results in increased expression of CAT protein]; Streptozocin inhibits the reaction [Streptozocin results in increased expression of CAT protein]; Streptozocin promotes the reaction [Chlorpyrifos results in increased activity of CAT protein]; Streptozocin results in decreased expression of and results in decreased activity of CAT protein; Streptozocin results in increased expression of and results in increased activity of CAT protein; Thioctic Acid inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; thymoquinone inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; Tocotrienols inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; U 78517F inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; vanillin inhibits the reaction [[Fructose co-treated with Streptozocin] results in decreased activity of CAT protein]; Zinc Compounds inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased activity of CAT protein]; Zinc inhibits the reaction [Streptozocin results in decreased activity of CAT protein]		 CTD PMID:9522273 PMID:11424224 PMID:12123627 PMID:12242689 PMID:15298345 More... NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cav1 caveolin 1 multiple interactions
increases expression		 EXP resveratrol inhibits the reaction [Streptozocin promotes the reaction [CAV1 protein binds to NOS3 protein]]; resveratrol inhibits the reaction [Streptozocin results in increased expression of CAV1 protein]; Streptozocin promotes the reaction [CAV1 protein binds to NOS3 protein] CTD PMID:18266981 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Cav3 caveolin 3 multiple interactions
decreases expression		 EXP resveratrol inhibits the reaction [Streptozocin inhibits the reaction [CAV3 protein binds to SLC2A4 protein]]; resveratrol inhibits the reaction [Streptozocin results in decreased expression of CAV3 protein]; Streptozocin inhibits the reaction [CAV3 protein binds to SLC2A4 protein] CTD PMID:18266981 NCBI chr 4:145,582,168...145,598,142
Ensembl chr 4:145,582,060...145,598,137 		JBrowse link
G Cbr1 carbonyl reductase 1 decreases activity EXP Streptozocin results in decreased activity of CBR1 protein CTD PMID:11057757 NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393 		JBrowse link
G Cbs cystathionine beta synthase multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of CBS mRNA CTD PMID:29127188 NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 affects response to substance
increases expression
multiple interactions
increases secretion		 ISO
EXP		 CCL2 affects the susceptibility to Streptozocin
Streptozocin results in increased expression of CCL2; Streptozocin results in increased expression of CCL2 mRNA; Streptozocin results in increased expression of CCL2 protein
[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of CCL2 protein; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of CCL2 protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; Flavonoids inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of CCL2 protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; moutan cortex inhibits the reaction [Streptozocin results in increased expression of and results in increased secretion of CCL2 protein]; Mycophenolic Acid inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; Mycophenolic Acid inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]; PD 123319 inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; Pentoxifylline inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]; procyanidin B2 inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; prolinedithiocarbamate inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]; Rosiglitazone inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; Streptozocin results in increased expression of and results in increased secretion of CCL2 protein; Valsartan inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]; vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]
4-(4-(3-adamantan-1-ylureido)cyclohexyloxy)benzoic acid inhibits the reaction [Streptozocin results in increased secretion of CCL2 protein]; [AM6545 co-treated with Perindopril] inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; [AM6545 co-treated with Perindopril] inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of CCL2 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of CCL2 protein; [fatostatin co-treated with Streptozocin] results in increased expression of CCL2 protein; [Streptozocin co-treated with Dietary Fats] results in increased secretion of CCL2 protein; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased secretion of CCL2 protein]; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]; EPHX2 gene mutant form inhibits the reaction [Streptozocin results in increased secretion of CCL2 protein]; esculetin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CCL2 protein]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CCL2 mRNA]; stannous mesoporphyrin inhibits the reaction [4-(4-(3-adamantan-1-ylureido)cyclohexyloxy)benzoic acid inhibits the reaction [Streptozocin results in increased secretion of CCL2 protein]]; Valsartan inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]		 CTD PMID:15284299 PMID:16374426 PMID:16684804 PMID:17624267 PMID:18413206 More... NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression
multiple interactions		 ISO Streptozocin results in increased expression of CCL3 mRNA
AM6545 inhibits the reaction [Streptozocin results in increased expression of CCL3 mRNA]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in increased expression of CCL3 mRNA]]; Perindopril inhibits the reaction [Streptozocin results in increased expression of CCL3 mRNA]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in increased expression of CCL3 mRNA]]		 CTD PMID:30184259 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression ISO Streptozocin results in increased expression of CCL5 mRNA CTD PMID:29420703 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Ccl9 C-C motif chemokine ligand 9 multiple interactions EXP [Resveratrol co-treated with Streptozocin] results in increased expression of CCL6 mRNA CTD PMID:25905778 NCBI chr10:68,366,486...68,371,408
Ensembl chr10:68,366,487...68,371,369 		JBrowse link
G Ccn2 cellular communication network factor 2 increases expression
multiple interactions		 ISO
EXP		 Streptozocin results in increased expression of CCN2; Streptozocin results in increased expression of CCN2 protein
[Streptozocin co-treated with Resveratrol co-treated with Ramipril] results in decreased expression of CCN2 protein; Acetylcysteine inhibits the reaction [Streptozocin results in increased expression of CCN2 protein]; Aspirin inhibits the reaction [Streptozocin results in increased expression of CCN2 mRNA]; Enalapril inhibits the reaction [Streptozocin results in increased expression of CCN2 protein]; fenugreek seed meal inhibits the reaction [Streptozocin results in increased expression of CCN2 mRNA]; fenugreek seed meal inhibits the reaction [Streptozocin results in increased expression of CCN2 protein]; idebenone inhibits the reaction [Streptozocin results in increased expression of CCN2 protein]; XLF-III-43 inhibits the reaction [Streptozocin results in increased expression of CCN2 protein]; Zinc inhibits the reaction [Streptozocin results in increased expression of CCN2 protein]
[Dietary Fats co-treated with Streptozocin] promotes the reaction [KLF15 gene mutant form results in increased expression of CCN2 protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of CCN2 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of CCN2 protein; CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CCN2 protein]; KLF15 gene mutant form inhibits the reaction [CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CCN2 protein]]; KLF15 gene mutant form promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CCN2 protein]; sulforaphane inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CCN2 protein]; sulforaphane inhibits the reaction [Streptozocin results in increased expression of CCN2 protein]
Streptozocin results in increased expression of CCN2 mRNA; Streptozocin results in increased expression of CCN2 protein		 CTD PMID:10026205 PMID:14586741 PMID:17270171 PMID:19369054 PMID:19657322 More... NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Ccnd1 cyclin D1 decreases expression
multiple interactions		 ISO Streptozocin results in decreased expression of CCND1 mRNA
5-Methoxypsoralen inhibits the reaction [Streptozocin results in decreased expression of CCND1 mRNA]; Tadalafil inhibits the reaction [Streptozocin results in decreased expression of CCND1 mRNA]		 CTD PMID:34428446 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccnd2 cyclin D2 decreases expression
multiple interactions		 ISO Streptozocin results in decreased expression of CCND2 protein
AM 251 inhibits the reaction [Streptozocin results in decreased expression of CCND2 protein]; CNR1 protein promotes the reaction [Streptozocin results in decreased expression of CCND2 protein]		 CTD PMID:26967640 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495 		JBrowse link
G Ccnt1 cyclin T1 multiple interactions EXP [Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 mRNA; [Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 protein; Berberine affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 mRNA]; Berberine affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 protein]; Fenofibrate affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 mRNA]; Fenofibrate affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 protein]; rosiglitazone affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 mRNA]; rosiglitazone affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 protein] CTD PMID:20828602 NCBI chr 7:129,687,146...129,718,080
Ensembl chr 7:129,691,209...129,717,871 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 increases expression
multiple interactions		 ISO Streptozocin results in increased expression of CCR2 mRNA
[AM6545 co-treated with Perindopril] inhibits the reaction [Streptozocin results in increased expression of CCR2 mRNA]; AM6545 inhibits the reaction [Streptozocin results in increased expression of CCR2 mRNA]; Perindopril inhibits the reaction [Streptozocin results in increased expression of CCR2 mRNA]		 CTD PMID:30184259 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100 		JBrowse link
G Ccs copper chaperone for superoxide dismutase decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of CCS mRNA; Streptozocin results in decreased expression of CCS protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of CCS mRNA]; Trientine inhibits the reaction [Streptozocin results in decreased expression of CCS protein]		 CTD PMID:24927960 NCBI chr 1:202,113,792...202,134,931
Ensembl chr 1:202,113,804...202,134,915 		JBrowse link
G Cd14 CD14 molecule multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of CD14 mRNA CTD PMID:29127188 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261 		JBrowse link
G Cd163 CD163 molecule multiple interactions
decreases expression		 EXP
ISO		 [resveratrol co-treated with Streptozocin] results in increased expression of CD163 mRNA
Streptozocin results in decreased expression of CD163 mRNA
AM6545 inhibits the reaction [Streptozocin results in decreased expression of CD163 mRNA]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in decreased expression of CD163 mRNA]]; Perindopril inhibits the reaction [Streptozocin results in decreased expression of CD163 mRNA]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in decreased expression of CD163 mRNA]]		 CTD PMID:25905778 PMID:30184259 NCBI chr 4:157,085,080...157,118,470
Ensembl chr 4:157,085,093...157,117,878 		JBrowse link
G Cd200r1l CD200 receptor 1-like multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of CD200R1L mRNA CTD PMID:25905778 NCBI chr11:55,842,632...55,860,914
Ensembl chr11:55,842,634...55,885,680 		JBrowse link
G Cd24 CD24 molecule multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of CD24A mRNA CTD PMID:29127188 NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662 		JBrowse link
G Cd36 CD36 molecule multiple interactions
increases expression		 ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of CD36 mRNA; Acrylamide inhibits the reaction [Streptozocin results in increased expression of CD36 mRNA] CTD PMID:29127188 PMID:34896238 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cd53 Cd53 molecule multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of CD53 mRNA CTD PMID:25905778 NCBI chr 2:194,352,139...194,399,668
Ensembl chr 2:194,352,139...194,399,657 		JBrowse link
G Cd5l Cd5 molecule-like multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of CD5L mRNA CTD PMID:25905778 NCBI chr 2:172,791,007...172,802,018
Ensembl chr 2:172,790,934...172,829,753 		JBrowse link
G Cd68 Cd68 molecule multiple interactions
increases expression		 EXP
ISO		 [resveratrol co-treated with Streptozocin] results in increased expression of CD68 mRNA; nifuroxazide inhibits the reaction [Streptozocin results in increased expression of CD68 protein]
Streptozocin results in increased expression of CD68 mRNA
AM6545 inhibits the reaction [Streptozocin results in increased expression of CD68 mRNA]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in increased expression of CD68 mRNA]]; Perindopril inhibits the reaction [Streptozocin results in increased expression of CD68 mRNA]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in increased expression of CD68 mRNA]]		 CTD PMID:25905778 PMID:29291386 PMID:30184259 NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697 		JBrowse link
G Cd80 Cd80 molecule multiple interactions
increases expression		 ISO Clodronic Acid inhibits the reaction [Streptozocin results in increased expression of CD80 protein] CTD PMID:15892581 NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030 		JBrowse link
G Cd86 CD86 molecule multiple interactions
increases expression		 ISO
EXP		 Clodronic Acid inhibits the reaction [Streptozocin results in increased expression of CD86 protein]
[resveratrol co-treated with Streptozocin] results in increased expression of CD86 mRNA		 CTD PMID:15892581 PMID:25905778 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818 		JBrowse link
G Cdca2 cell division cycle associated 2 multiple interactions ISO [Diethylhexyl Phthalate co-treated with Streptozocin co-treated with Dietary Fats] results in increased expression of CDCA2 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of CDCA2 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CDCA2 mRNA] CTD PMID:33484791 NCBI chr15:41,895,946...41,942,226
Ensembl chr15:41,895,901...41,941,611 		JBrowse link
G Cdh1 cadherin 1 decreases expression EXP Streptozocin results in decreased expression of CDH1 CTD PMID:32469605 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Cdh2 cadherin 2 decreases expression
multiple interactions		 ISO Streptozocin results in decreased expression of CDH2 protein
rhodioloside inhibits the reaction [Streptozocin results in decreased expression of CDH2 protein]		 CTD PMID:31682803 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167 		JBrowse link
G Cdk15 cyclin-dependent kinase 15 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of CDK15 mRNA CTD PMID:33484791 NCBI chr 9:60,710,787...60,803,638
Ensembl chr 9:60,711,715...60,802,777 		JBrowse link
G Cdk9 cyclin-dependent kinase 9 multiple interactions
increases phosphorylation		 EXP
ISO		 [Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 mRNA; [Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 protein; Berberine affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 mRNA]; Berberine affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 protein]; Fenofibrate affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 mRNA]; Fenofibrate affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 protein]; rosiglitazone affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 mRNA]; rosiglitazone affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 protein]
Streptozocin results in increased phosphorylation of CDK9 protein		 CTD PMID:20828602 PMID:33631230 NCBI chr 3:15,996,467...16,001,315
Ensembl chr 3:15,996,468...16,002,410 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression		 ISO
EXP		 2-amino-6-boronohexanoic acid inhibits the reaction [Streptozocin results in increased expression of CDKN1A mRNA]; [Dietary Fats co-treated with Streptozocin] results in increased expression of CDKN1A protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of CDKN1A mRNA; Quercetin inhibits the reaction [Streptozocin results in increased expression of CDKN1A mRNA]; SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of CDKN1A]
Streptozocin results in increased expression of CDKN1A; Streptozocin results in increased expression of CDKN1A mRNA
Streptozocin results in increased expression of CDKN1A mRNA; Streptozocin results in increased expression of CDKN1A protein
Organoselenium Compounds inhibits the reaction [Streptozocin results in increased expression of CDKN1A protein]; Streptozocin promotes the reaction [SETD7 protein binds to CDKN1A promoter]		 CTD PMID:19496084 PMID:22744176 PMID:25301743 PMID:27652271 PMID:29127188 More... NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A increases expression
multiple interactions		 ISO Streptozocin results in increased expression of CDKN2A mRNA; Streptozocin results in increased expression of CDKN2A protein
2-amino-6-boronohexanoic acid inhibits the reaction [Streptozocin results in increased expression of CDKN2A mRNA]; 2-amino-6-boronohexanoic acid inhibits the reaction [Streptozocin results in increased expression of CDKN2A protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of CDKN2A protein; NTN1 protein inhibits the reaction [Streptozocin results in increased expression of CDKN2A mRNA]; NTN1 protein inhibits the reaction [Streptozocin results in increased expression of CDKN2A protein]		 CTD PMID:29059224 PMID:29673160 PMID:38483099 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions
decreases expression		 ISO CEBPB protein affects the reaction [Streptozocin results in increased expression of AGT protein]; CEBPB protein affects the reaction [Streptozocin results in increased expression of TGFB1 protein]; CEBPB protein inhibits the reaction [Streptozocin results in decreased abundance of AGT protein modified form]; CEBPB protein inhibits the reaction [Streptozocin results in decreased abundance of angiotensin I (1-7)]; CEBPB protein inhibits the reaction [Streptozocin results in decreased expression of ACE2 protein]; CEBPB protein inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; CEBPB protein inhibits the reaction [Streptozocin results in decreased expression of MAS1 protein]; CEBPB protein inhibits the reaction [Streptozocin results in decreased expression of MMP2 protein]; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of ACE protein]; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of AGTR1 protein]; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of AGTR2 protein]; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of BAX protein]; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of IL6 protein]
Streptozocin results in decreased expression of CEBPB protein		 CTD PMID:29266779 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473 		JBrowse link
G Cebpd CCAAT/enhancer binding protein delta multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of CEBPD mRNA CTD PMID:25905778 NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829 		JBrowse link
G Celf2 CUGBP, Elav-like family member 2 multiple interactions ISO [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of CELF2 mRNA]; [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of CELF2 protein]; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of CELF2 mRNA; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of CELF2 protein CTD PMID:38282657 NCBI chr17:70,904,462...71,729,072
Ensembl chr17:71,210,853...71,728,333 		JBrowse link
G Celf4 CUGBP, Elav-like family member 4 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of CELF4 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CELF4 mRNA] CTD PMID:33484791 NCBI chr18:16,786,578...17,065,045
Ensembl chr18:16,786,867...17,064,786 		JBrowse link
G Ces2c carboxylesterase 2C multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of CES2C mRNA CTD PMID:25905778 NCBI chr 1:260,391,190...260,398,757
Ensembl chr 1:260,388,902...260,398,790 		JBrowse link
G Ces4a carboxylesterase 4A multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of CES4A mRNA CTD PMID:33484791 NCBI chr19:33,011,731...33,030,119
Ensembl chr19:33,011,731...33,029,545 		JBrowse link
G Cfap45 cilia and flagella associated protein 45 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of CFAP45 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CFAP45 mRNA] CTD PMID:33484791 NCBI chr13:84,989,474...85,012,880
Ensembl chr13:84,981,728...85,012,878 		JBrowse link
G Cfap69 cilia and flagella associated protein 69 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of CFAP69 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CFAP69 mRNA] CTD PMID:33484791 NCBI chr 4:28,379,604...28,452,562
Ensembl chr 4:28,375,996...28,450,698 		JBrowse link
G Cfd complement factor D increases expression EXP Streptozocin results in increased expression of CFD mRNA CTD PMID:3299706 NCBI chr 7:9,813,148...9,814,871
Ensembl chr 7:9,813,150...9,815,053 		JBrowse link
G Cfl1 cofilin 1 multiple interactions
increases phosphorylation		 EXP fasudil inhibits the reaction [Streptozocin results in increased phosphorylation of CFL1 protein] CTD PMID:22062134 NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587 		JBrowse link
G Cfp complement factor properdin multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of CFP mRNA CTD PMID:25905778 NCBI chr  X:1,162,014...1,167,576
Ensembl chr  X:1,161,979...1,167,573 		JBrowse link
G Chat choline O-acetyltransferase multiple interactions
affects localization
decreases expression		 EXP Inositol inhibits the reaction [Streptozocin affects the localization of CHAT protein]; Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of CHAT protein]; Rivastigmine inhibits the reaction [Streptozocin results in decreased expression of CHAT protein] CTD PMID:2431858 PMID:32805344 NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093 		JBrowse link
G Chga chromogranin A multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of CHGA mRNA CTD PMID:33484791 NCBI chr 6:121,696,051...121,707,399
Ensembl chr 6:121,696,051...121,707,398 		JBrowse link
G Chka choline kinase alpha multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of CHKA mRNA CTD PMID:29127188 NCBI chr 1:201,076,804...201,125,517
Ensembl chr 1:201,076,860...201,125,516 		JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 multiple interactions
affects expression
increases expression		 EXP 1-hexacosanol inhibits the reaction [Streptozocin affects the expression of CHRM2 mRNA]; Phlorhizin inhibits the reaction [Streptozocin results in increased expression of CHRM2 mRNA]; Phlorhizin inhibits the reaction [Streptozocin results in increased expression of CHRM2 protein]
Streptozocin results in increased expression of CHRM2 mRNA; Streptozocin results in increased expression of CHRM2 protein		 CTD PMID:17989502 PMID:18715473 NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103 		JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 multiple interactions
affects expression		 EXP 1-hexacosanol inhibits the reaction [Streptozocin affects the expression of CHRM3 mRNA] CTD PMID:17989502 NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278 		JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of CHRNA4 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CHRNA4 mRNA] CTD PMID:33484791 NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957 		JBrowse link
G Chst8 carbohydrate sulfotransferase 8 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of CHST8 mRNA CTD PMID:33484791 NCBI chr 1:87,294,144...87,435,900
Ensembl chr 1:87,294,540...87,435,900 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions
increases expression		 EXP Quercetin inhibits the reaction [Streptozocin results in increased expression of CHUK protein] CTD PMID:16177186 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065 		JBrowse link
G Cidea cell death-inducing DFFA-like effector a multiple interactions EXP
ISO		 [resveratrol co-treated with Streptozocin] results in increased expression of CIDEA mRNA
[Streptozocin co-treated with Dietary Fats] results in increased expression of CIDEA mRNA		 CTD PMID:25905778 PMID:29127188 NCBI chr18:60,894,917...60,920,485
Ensembl chr18:60,894,874...60,920,481 		JBrowse link
G Cisd1 CDGSH iron sulfur domain 1 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of CISD1 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of CISD1 protein]		 CTD PMID:19634143 NCBI chr20:17,255,302...17,268,688
Ensembl chr20:17,255,151...17,284,924 		JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 increases expression
multiple interactions
decreases expression		 EXP
ISO		 Streptozocin results in increased expression of CITED2 mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of CITED2 mRNA]
SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of CITED2 mRNA]		 CTD PMID:16684804 PMID:27629361 NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897 		JBrowse link
G Ckmt2 creatine kinase, mitochondrial 2 multiple interactions
decreases expression		 EXP vanadyl sulfate inhibits the reaction [Streptozocin results in decreased expression of CKMT2 mRNA] CTD PMID:16684804 NCBI chr 2:23,079,918...23,110,518
Ensembl chr 2:23,079,918...23,110,430 		JBrowse link
G Cldn1 claudin 1 decreases expression EXP Streptozocin results in decreased expression of CLDN1 mRNA CTD PMID:25905778 NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724 		JBrowse link
G Cldn11 claudin 11 decreases expression
multiple interactions		 ISO Streptozocin results in decreased expression of CLDN11 protein
rhodioloside inhibits the reaction [Streptozocin results in decreased expression of CLDN11 protein]		 CTD PMID:31682803 NCBI chr 2:112,207,745...112,221,050
Ensembl chr 2:112,207,745...112,221,050 		JBrowse link
G Cldn2 claudin 2 decreases expression EXP Streptozocin results in decreased expression of CLDN2 mRNA CTD PMID:25905778 NCBI chr  X:103,459,870...103,473,794
Ensembl chr  X:103,459,780...103,474,838 		JBrowse link
G Clec4d C-type lectin domain family 4, member D multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of CLEC4D mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CLEC4D mRNA] CTD PMID:33484791 NCBI chr 4:156,589,591...156,599,279
Ensembl chr 4:156,589,792...156,598,848 		JBrowse link
G Clec4f C-type lectin domain family 4, member F multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of CLEC4F mRNA CTD PMID:25905778 NCBI chr 4:116,129,023...116,138,744
Ensembl chr 4:116,129,023...116,138,775 		JBrowse link
G Clic4 chloride intracellular channel 4 affects expression ISO Streptozocin affects the expression of CLIC4 mRNA CTD PMID:18583417 NCBI chr 5:147,453,702...147,513,455
Ensembl chr 5:147,453,712...147,513,452 		JBrowse link
G Clpp caseinolytic mitochondrial matrix peptidase proteolytic subunit affects expression ISO Streptozocin affects the expression of CLPP mRNA CTD PMID:18583417 NCBI chr 9:1,831,680...1,837,700
Ensembl chr 9:1,830,311...1,837,693 		JBrowse link
G Clu clusterin increases expression
multiple interactions		 EXP Streptozocin results in increased expression of CLU protein
Trientine inhibits the reaction [Streptozocin results in increased expression of CLU protein]		 CTD PMID:19634143 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315 		JBrowse link
G Cnpy1 canopy FGF signaling regulator 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of CNPY1 mRNA CTD PMID:33484791 NCBI chr 4:7,182,311...7,191,408
Ensembl chr 4:7,136,533...7,189,761 		JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions
increases expression
decreases expression		 EXP
ISO		 [Fructose co-treated with Streptozocin] results in decreased expression of CNR1 mRNA; Ghrelin inhibits the reaction [[Fructose co-treated with Streptozocin] results in decreased expression of CNR1 mRNA]
Streptozocin results in increased expression of CNR1 mRNA; Streptozocin results in increased expression of CNR1 protein
[Streptozocin co-treated with CNR1 protein] affects the expression of IGF1R protein; [Streptozocin co-treated with CNR1 protein] affects the phosphorylation of AKT1 protein; CNR1 protein promotes the reaction [Streptozocin results in decreased expression of BCL2 protein]; CNR1 protein promotes the reaction [Streptozocin results in decreased expression of CCND2 protein]; CNR1 protein promotes the reaction [Streptozocin results in decreased expression of INS1 protein]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of CNR1 mRNA]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of CNR1 protein]
Streptozocin results in decreased expression of CNR1 protein		 CTD PMID:26967640 PMID:30184259 PMID:30642005 PMID:30721768 PMID:31468622 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099 		JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions
increases expression		 ISO [Dietary Fats co-treated with Streptozocin] results in increased expression of COL1A1 mRNA; Curcumin analog inhibits the reaction [Streptozocin results in increased expression of COL1A1 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of COL1A1 mRNA]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of COL1A1 mRNA] CTD PMID:28700904 PMID:29988851 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Col3a1 collagen type III alpha 1 chain multiple interactions
increases expression		 EXP
ISO		 INS1 protein inhibits the reaction [Streptozocin results in increased expression of COL3A1 protein]
Valsartan inhibits the reaction [Streptozocin results in increased expression of COL3A1 protein]		 CTD PMID:29266779 PMID:29682576 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547 		JBrowse link
G Col4a1 collagen type IV alpha 1 chain decreases expression
increases expression
multiple interactions		 ISO
EXP		 Streptozocin results in decreased expression of COL4A1 mRNA
Streptozocin results in increased expression of COL4A1 mRNA
benazepril inhibits the reaction [Streptozocin results in increased expression of COL4A1 mRNA]; MFN2 protein mutant form inhibits the reaction [Streptozocin promotes the reaction [TFAP2A protein binds to COL4A1 promoter]]; MFN2 protein mutant form inhibits the reaction [Streptozocin results in increased expression of COL4A1 mRNA]; Streptozocin promotes the reaction [TFAP2A protein binds to COL4A1 promoter]
[fatostatin co-treated with Streptozocin] results in increased expression of COL4A1 mRNA		 CTD PMID:11798618 PMID:15496156 PMID:17582205 PMID:27997345 PMID:29420703 NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412 		JBrowse link
G Col4a2 collagen type IV alpha 2 chain increases expression
multiple interactions		 ISO Streptozocin results in increased expression of COL4A2 mRNA
MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of COL4A2 mRNA]		 CTD PMID:30642005 NCBI chr16:78,047,591...78,183,360
Ensembl chr16:78,047,602...78,183,839 		JBrowse link
G Col4a3 collagen type IV alpha 3 chain multiple interactions
increases expression		 EXP Zinc inhibits the reaction [Streptozocin results in increased expression of COL4A3 mRNA] CTD PMID:31009641 NCBI chr 9:83,875,849...84,004,955
Ensembl chr 9:83,875,561...84,001,895 		JBrowse link
G Col4a4 collagen type IV alpha 4 chain multiple interactions
increases expression		 ISO 3-((6-(2-methoxyphenyl)pyrimidin-4-yl)amino)phenyl)methane sulfonamide inhibits the reaction [Streptozocin results in increased expression of COL4A4 mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of COL4A4 mRNA] CTD PMID:33631230 NCBI chr 9:83,833,173...83,875,436
Ensembl chr 9:83,755,515...83,875,876 		JBrowse link
G Col6a1 collagen type VI alpha 1 chain increases expression
multiple interactions		 EXP Streptozocin results in increased expression of COL6A1 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of COL6A1 protein]		 CTD PMID:19634143 NCBI chr20:11,906,105...11,924,599
Ensembl chr20:11,905,957...11,924,597 		JBrowse link
G Col6a2 collagen type VI alpha 2 chain increases expression
multiple interactions		 EXP Streptozocin results in increased expression of COL6A2 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of COL6A2 protein]		 CTD PMID:19634143 NCBI chr20:12,021,676...12,049,425
Ensembl chr20:12,021,767...12,057,564 		JBrowse link
G Col6a3 collagen type VI alpha 3 chain increases expression
multiple interactions		 EXP Streptozocin results in increased expression of COL6A3 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of COL6A3 protein]		 CTD PMID:19634143 NCBI chr 9:91,361,578...91,439,434
Ensembl chr 9:91,361,583...91,439,471 		JBrowse link
G Col7a1 collagen type VII alpha 1 chain multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of COL7A1 mRNA CTD PMID:33484791 NCBI chr 8:109,604,877...109,637,249
Ensembl chr 8:109,604,861...109,637,252 		JBrowse link
G Cotl1 coactosin-like F-actin binding protein 1 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of COTL1 mRNA CTD PMID:25905778 NCBI chr19:47,871,689...47,906,010
Ensembl chr19:47,871,694...47,911,689 		JBrowse link
G Cox17 cytochrome c oxidase copper chaperone COX17 affects expression ISO Streptozocin affects the expression of COX17 mRNA CTD PMID:18583417 NCBI chr11:62,400,733...62,406,507 JBrowse link
G Cox5b cytochrome c oxidase subunit 5B multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of COX5B mRNA; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of COX5B mRNA] CTD PMID:37337224 NCBI chr 9:38,921,980...38,923,806
Ensembl chr 9:38,921,967...38,925,052 		JBrowse link
G Cp ceruloplasmin multiple interactions
decreases expression		 EXP caryophyllene inhibits the reaction [Streptozocin results in decreased expression of CP protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of CP protein] CTD PMID:26748309 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075 		JBrowse link
G Cpeb2 cytoplasmic polyadenylation element binding protein 2 multiple interactions ISO [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of CPEB2 mRNA]; [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of CPEB2 protein] CTD PMID:38282657 NCBI chr14:67,787,503...67,839,973
Ensembl chr14:67,787,507...67,840,743 		JBrowse link
G Cpeb4 cytoplasmic polyadenylation element binding protein 4 multiple interactions ISO [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of CPEB4 mRNA; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of CPEB4 protein CTD PMID:38282657 NCBI chr10:15,717,794...15,780,482
Ensembl chr10:15,717,794...15,780,603 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression
multiple interactions		 EXP
ISO		 Streptozocin results in increased expression of CPT1A mRNA
[resveratrol co-treated with Streptozocin] results in decreased expression of CPT1A mRNA; vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of CPT1A mRNA]
[Dietary Fats co-treated with Streptozocin] results in decreased expression of CPT1A mRNA; Acrylamide inhibits the reaction [Streptozocin results in increased expression of CPT1A mRNA]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of CPT1A mRNA]		 CTD PMID:16684804 PMID:25905778 PMID:29988851 PMID:34896238 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055 		JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of CPT2 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of CPT2 protein]		 CTD PMID:21136691 NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions
decreases phosphorylation		 EXP
ISO		 [Streptozocin co-treated with Dietary Fats] results in decreased expression of CREB1 mRNA; Memantine inhibits the reaction [Streptozocin results in decreased phosphorylation of CREB1 protein]; xanthoceraside inhibits the reaction [Streptozocin results in decreased phosphorylation of CREB1 protein]
[Streptozocin co-treated with Dietary Fats] results in increased expression of CREB1 protein; CREB1 protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein]; HDAC3 protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CREB1 protein]; MIR10A mRNA affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CREB1 protein]		 CTD PMID:20665664 PMID:23562514 PMID:27292126 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Crebbp CREB binding protein decreases expression EXP Streptozocin results in decreased expression of CREBBP mRNA CTD PMID:25905778 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888 		JBrowse link
G Crot carnitine O-octanoyltransferase decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of CROT mRNA
[resveratrol co-treated with Streptozocin] results in decreased expression of CROT mRNA		 CTD PMID:25905778 NCBI chr 4:25,068,270...25,133,111
Ensembl chr 4:25,080,587...25,133,109 		JBrowse link
G Crp C-reactive protein multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of CRP protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CRP protein] CTD PMID:33484791 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178 		JBrowse link
G Cry1 cryptochrome circadian regulator 1 increases expression EXP Streptozocin results in increased expression of CRY1 mRNA CTD PMID:25905778 NCBI chr 7:18,529,823...18,594,092
Ensembl chr 7:18,529,823...18,594,091 		JBrowse link
G Crybb3 crystallin, beta B3 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of CRYBB3 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CRYBB3 mRNA] CTD PMID:33484791 NCBI chr12:43,557,103...43,562,120
Ensembl chr12:43,557,103...43,562,120 		JBrowse link
G Cryz crystallin zeta decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of CRYZ protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of CRYZ protein]		 CTD PMID:19634143 NCBI chr 2:243,552,037...243,580,369
Ensembl chr 2:243,552,119...243,579,758 		JBrowse link
G Csf1r colony stimulating factor 1 receptor multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of CSF1R mRNA CTD PMID:25905778 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415 		JBrowse link
G Csrp3 cysteine and glycine rich protein 3 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of CSRP3 mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of CSRP3 mRNA]		 CTD PMID:16684804 NCBI chr 1:98,528,067...98,546,647
Ensembl chr 1:98,528,068...98,546,653 		JBrowse link
G Cst3 cystatin C multiple interactions
increases expression		 EXP [Streptozocin co-treated with Fructose] results in increased expression of CST3 protein; Glyburide inhibits the reaction [Streptozocin results in increased expression of CST3 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of CST3 protein]; Tropisetron inhibits the reaction [Streptozocin results in increased expression of CST3 protein] CTD PMID:30551545 PMID:33387473 NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822 		JBrowse link
G Cth cystathionine gamma-lyase multiple interactions ISO [Streptozocin co-treated with Dietary Fats] affects the expression of CTH mRNA CTD PMID:29127188 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234 		JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions
increases phosphorylation		 ISO 5-Methoxypsoralen inhibits the reaction [Streptozocin results in increased phosphorylation of CTNNB1 protein]; Tadalafil inhibits the reaction [Streptozocin results in increased phosphorylation of CTNNB1 protein] CTD PMID:34428446 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Ctsd cathepsin D increases expression ISO Streptozocin results in increased expression of CTSD protein CTD PMID:28468961 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488 		JBrowse link
G Ctsk cathepsin K increases expression
multiple interactions		 EXP
ISO		 Streptozocin results in increased expression of CTSK mRNA; Streptozocin results in increased expression of CTSK protein
formononetin inhibits the reaction [Streptozocin results in increased expression of CTSK mRNA]; formononetin inhibits the reaction [Streptozocin results in increased expression of CTSK protein]		 CTD PMID:25617479 PMID:35315182 NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550 		JBrowse link
G Ctss cathepsin S increases expression
multiple interactions		 EXP Streptozocin results in increased expression of CTSS mRNA
[resveratrol co-treated with Streptozocin] results in increased expression of CTSS mRNA; vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of CTSS mRNA]		 CTD PMID:16684804 PMID:25905778 NCBI chr 2:183,086,437...183,114,483
Ensembl chr 2:183,086,437...183,114,483 		JBrowse link
G Cubn cubilin multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of CUBN protein; bicalutamide promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CUBN protein] CTD PMID:35151640 NCBI chr17:76,385,046...76,593,133
Ensembl chr17:76,385,060...76,593,231 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 multiple interactions EXP [Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in increased expression of CXCL1 protein]; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in increased expression of CXCL1 protein]] CTD PMID:36547818 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 multiple interactions
decreases expression		 ISO [Streptozocin co-treated with Oxygen deficiency] results in decreased expression of CXCL12 mRNA; CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of KLF15 protein]; CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CCN2 protein]; CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FN1 protein]; CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein]; KLF15 gene mutant form inhibits the reaction [CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CCN2 protein]]; KLF15 gene mutant form inhibits the reaction [CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FN1 protein]]; KLF15 gene mutant form inhibits the reaction [CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein]]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [[Streptozocin co-treated with Oxygen deficiency] results in decreased expression of CXCL12 mRNA]
Streptozocin results in decreased expression of CXCL12 mRNA; Streptozocin results in decreased expression of CXCL12 protein		 CTD PMID:18227068 PMID:34310909 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 multiple interactions EXP [Streptozocin co-treated with Tobacco Smoke Pollution] results in increased expression of CXCR4 protein CTD PMID:30421503 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883 		JBrowse link
G Cyb561 cytochrome b-561 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of CYB561 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CYB561 mRNA] CTD PMID:33484791 NCBI chr10:90,878,052...90,888,734
Ensembl chr10:90,878,054...90,884,787 		JBrowse link
G Cyba cytochrome b-245 alpha chain multiple interactions
increases expression		 EXP [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of CYBA mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in increased expression of CYBA protein; [Carbamazepine affects the susceptibility to [Dietary Fats co-treated with Streptozocin]] which results in decreased expression of CYBA mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of CYBA protein; [Resveratrol co-treated with Streptozocin] results in increased expression of CYBA mRNA; Bezafibrate inhibits the reaction [Streptozocin results in increased expression of CYBA mRNA]; candesartan inhibits the reaction [Streptozocin results in increased expression of CYBA mRNA] CTD PMID:12967931 PMID:16139267 PMID:25905778 PMID:35786680 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721 		JBrowse link
G Cybb cytochrome b-245 beta chain increases expression
multiple interactions		 ISO
EXP		 Streptozocin results in increased expression of CYBB mRNA; Streptozocin results in increased expression of CYBB protein
2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of NOX2 mRNA]; [fatostatin co-treated with Streptozocin] results in increased expression of CYBB mRNA; [Streptozocin co-treated with Niacinamide] results in increased expression of NOX2 mRNA; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of NOX2 mRNA]; Telmisartan inhibits the reaction [Streptozocin results in increased expression of CYBB protein]
[Streptozocin co-treated with Dietary Fats] results in increased expression of CYBB protein; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CYBB protein]		 CTD PMID:19957251 PMID:21381899 PMID:29420703 PMID:35085591 PMID:37120126 NCBI chr  X:13,358,101...13,392,570
Ensembl chr  X:13,359,430...13,392,586 		JBrowse link
G Cyc1 cytochrome c-1 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of CYC1 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of CYC1 protein]		 CTD PMID:19634143 NCBI chr 7:108,067,106...108,069,483
Ensembl chr 7:108,067,115...108,069,479 		JBrowse link
G Cycs cytochrome c, somatic affects localization
multiple interactions
increases expression		 EXP
ISO		 Streptozocin affects the localization of CYCS protein
arjunolic acid inhibits the reaction [Streptozocin affects the localization of CYCS protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of CYCS mRNA]; morin inhibits the reaction [Streptozocin results in increased expression of CYCS mRNA]; Phosphocreatine inhibits the reaction [Streptozocin results in increased expression of CYCS protein]; Thioctic Acid inhibits the reaction [Streptozocin affects the localization of CYCS protein]
Streptozocin results in increased expression of CYCS mRNA; Streptozocin results in increased expression of CYCS protein
Metformin inhibits the reaction [Streptozocin affects the localization of CYCS protein]; phillyrin inhibits the reaction [Streptozocin affects the localization of CYCS protein]		 CTD PMID:19682444 PMID:19951573 PMID:34455488 PMID:34649470 PMID:35414346 More... NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054 		JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 increases expression EXP Streptozocin results in increased expression of CYP11B2 mRNA; Streptozocin results in increased expression of CYP11B2 protein CTD PMID:16043663 NCBI chr 7:106,808,559...106,814,048
Ensembl chr 7:106,808,559...106,814,048 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression		 ISO
EXP		 Metformin promotes the reaction [Streptozocin results in increased expression of CYP1A1 mRNA]; Streptozocin promotes the reaction [Dietary Fats results in decreased expression of CYP1A1 mRNA]
[resveratrol co-treated with Streptozocin] results in increased expression of CYP1A1 mRNA		 CTD PMID:22342832 PMID:25905778 PMID:29382564 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases expression
increases expression
multiple interactions		 ISO
EXP		 Streptozocin results in decreased expression of CYP1A2 protein
Streptozocin results in increased expression of CYP1A2 protein
[resveratrol co-treated with Streptozocin] results in decreased expression of CYP1A2 mRNA; [Streptozocin results in increased expression of CYP1A2 protein] which results in increased metabolism of Diazinon
Streptozocin results in decreased expression of CYP1A2 mRNA
[Streptozocin co-treated with Dietary Fats] results in decreased expression of CYP1A2 mRNA		 CTD PMID:12700423 PMID:17442507 PMID:25905778 PMID:29127188 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of CYP26A1 mRNA CTD PMID:25905778 NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204 		JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of CYP26B1 mRNA CTD PMID:25905778 NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628 		JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 multiple interactions ISO [Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP27A1 mRNA CTD PMID:29382564 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551 		JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 decreases expression
multiple interactions		 EXP
ISO		 Streptozocin results in decreased expression of CYP2A1 mRNA
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of CYP2A22 mRNA		 CTD PMID:25905778 PMID:33484791 NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887 		JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of CYP2A4 mRNA CTD PMID:33484791 NCBI chr 1:82,171,914...82,179,980
Ensembl chr 1:82,169,949...82,179,979 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of CYP2B1 mRNA
[resveratrol co-treated with Streptozocin] results in increased expression of CYP2B1 mRNA		 CTD PMID:25905778 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052 		JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of CYP2B13 mRNA CTD PMID:29127188 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression
multiple interactions		 ISO Streptozocin results in increased expression of CYP2B10 mRNA
Berberine inhibits the reaction [Streptozocin results in increased expression of CYP2B10 mRNA]; Streptozocin promotes the reaction [Dietary Fats results in decreased expression of CYP2B10 mRNA]		 CTD PMID:22342832 PMID:29382564 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 multiple interactions EXP [Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP2C11 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP2C11 protein CTD PMID:24815820 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases expression
increases expression
multiple interactions		 ISO
EXP		 Streptozocin results in decreased expression of CYP2E1 protein
Streptozocin results in increased expression of CYP2E1 mRNA; Streptozocin results in increased expression of CYP2E1 protein
[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased activity of CYP2E1 protein		 CTD PMID:11752103 PMID:12700423 PMID:14693714 PMID:24815820 PMID:25905778 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 increases expression EXP Streptozocin results in increased expression of CYP2J4 mRNA CTD PMID:25905778 NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794 		JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of CYP4A1 mRNA
[Dietary Fats co-treated with Streptozocin] results in increased expression of CYP4A1 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of CYP4A1 protein; [Resveratrol co-treated with Streptozocin] results in decreased expression of CYP4A1 mRNA		 CTD PMID:24815820 PMID:25905778 NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464 		JBrowse link
G Cyp4a2 cytochrome P450, family 4, subfamily a, polypeptide 2 decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of CYP4A2 protein
[Dietary Fats co-treated with Streptozocin] results in increased expression of CYP4A2 mRNA; Trientine promotes the reaction [Streptozocin results in decreased expression of CYP4A2 protein]		 CTD PMID:19634143 PMID:24815820 NCBI chr 5:128,922,355...128,934,188
Ensembl chr 5:128,923,615...128,934,165 		JBrowse link
G Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of CYP4F14 mRNA CTD PMID:29127188 NCBI chr 7:12,010,850...12,022,497
Ensembl chr 7:12,010,852...12,022,046 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 increases expression
multiple interactions		 EXP
ISO		 Streptozocin results in increased expression of CYP7A1 mRNA
[Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 protein; Acrylamide inhibits the reaction [Streptozocin results in increased expression of CYP7A1 mRNA]
[Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 protein; Fungal Polysaccharides inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 mRNA]; Fungal Polysaccharides inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 protein]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 mRNA]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 protein]		 CTD PMID:10393316 PMID:29382564 PMID:31100278 PMID:34896238 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688 		JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 multiple interactions ISO [Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7B1 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of CYP7B1 mRNA CTD PMID:29127188 PMID:29382564 NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698 		JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 multiple interactions
increases expression		 EXP
ISO		 [resveratrol co-treated with Streptozocin] results in decreased expression of CYP8B1 mRNA; INS1 protein inhibits the reaction [Streptozocin results in increased expression of CYP8B1 mRNA]; Streptozocin inhibits the reaction [resveratrol results in increased expression of CYP8B1 mRNA]
Streptozocin results in increased expression of CYP8B1 mRNA; Streptozocin results in increased expression of CYP8B1 protein
[Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP8B1 mRNA		 CTD PMID:10393316 PMID:25905778 PMID:29382564 NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166 		JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 multiple interactions
increases expression		 ISO montelukast inhibits the reaction [Streptozocin results in increased expression of CYSLTR1 mRNA]; montelukast inhibits the reaction [Streptozocin results in increased expression of CYSLTR1 protein]
Streptozocin results in increased expression of CYSLTR1 mRNA; Streptozocin results in increased expression of CYSLTR1 protein		 CTD PMID:27702591 NCBI chr  X:71,661,421...71,690,012
Ensembl chr  X:71,663,821...71,690,121 		JBrowse link
G Cyyr1 cysteine and tyrosine rich 1 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of CYYR1 mRNA CTD PMID:25905778 NCBI chr11:24,557,620...24,664,007
Ensembl chr11:24,515,316...24,663,961 		JBrowse link
G Dao D-amino-acid oxidase increases expression
multiple interactions		 EXP Streptozocin results in increased expression of DAO protein
Trientine inhibits the reaction [Streptozocin results in increased expression of DAO protein]		 CTD PMID:19634143 NCBI chr12:42,592,342...42,613,046
Ensembl chr12:42,592,343...42,612,741 		JBrowse link
G Dapk1 death associated protein kinase 1 decreases expression EXP Streptozocin results in decreased expression of DAPK1 mRNA CTD PMID:25905778 NCBI chr17:3,930,223...4,090,991
Ensembl chr17:3,930,213...4,090,991 		JBrowse link
G Dapl1 death associated protein-like 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of DAPL1 mRNA CTD PMID:33484791 NCBI chr 3:43,960,993...43,980,940
Ensembl chr 3:43,960,810...43,980,940 		JBrowse link
G Dbn1 drebrin 1 decreases expression EXP Streptozocin results in decreased expression of DBN1 protein CTD PMID:23333261 NCBI chr17:9,150,608...9,164,982
Ensembl chr17:9,150,659...9,164,984 		JBrowse link
G Dbt dihydrolipoamide branched chain transacylase E2 affects expression ISO Streptozocin affects the expression of DBT mRNA CTD PMID:18583417 NCBI chr 2:204,481,744...204,510,612
Ensembl chr 2:204,481,737...204,510,609 		JBrowse link
G Dcc DCC netrin 1 receptor multiple interactions
increases expression		 ISO NTN1 protein promotes the reaction [Streptozocin results in increased expression of DCC mRNA]; NTN1 protein promotes the reaction [Streptozocin results in increased expression of DCC protein]
Streptozocin results in increased expression of DCC mRNA; Streptozocin results in increased expression of DCC protein		 CTD PMID:29059224 NCBI chr18:64,868,987...65,972,783
Ensembl chr18:64,873,898...65,972,740 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions
increases expression 		ISO
EXP		 Streptozocin results in increased expression of DDIT3; Streptozocin results in increased expression of DDIT3 mRNA; Streptozocin results in increased expression of DDIT3 protein
[Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of DDIT3 mRNA]; [Streptozocin co-treated with bisphenol A] results in increased expression of DDIT3 protein; [Streptozocin co-treated with Ethinyl Estradiol] results in increased expression of DDIT3 mRNA; [Streptozocin co-treated with Ethinyl Estradiol] results in increased expression of DDIT3 protein; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of DDIT3 mRNA; [Streptozocin co-treated with octylphenol] results in increased expression of DDIT3 mRNA; [Streptozocin co-treated with octylphenol] results in increased expression of DDIT3 protein; FGF21 protein affects the reaction [Streptozocin results in increased expression of DDIT3]; Streptozocin promotes the reaction [bisphenol A results in increased expression of DDIT3 mRNA]; sulforaphane inhibits the reaction [Streptozocin results in increased expression of DDIT3 protein]
4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of DDIT3 protein]; [Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of DDIT3 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of DDIT3 mRNA; Bilirubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of DDIT3 mRNA]; Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of DDIT3 protein]; Vitamin B 12 inhibits the reaction [Streptozocin results in increased expression of DDIT3 protein]
streptozocin increases expression of Ddit3 protein in heart		 CTD
RGD		 PMID:23499715 PMID:24967692 PMID:29935216 PMID:30980806 PMID:34801538 More... RGD:156430337 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of DDIT4 mRNA CTD PMID:25905778 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105 		JBrowse link
G Decr1 2,4-dienoyl-CoA reductase 1 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of DECR1 mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of DECR1 mRNA]		 CTD PMID:16684804 NCBI chr 5:29,411,172...29,439,054
Ensembl chr 5:29,411,172...29,439,018 		JBrowse link
G Derl1 derlin 1 multiple interactions
increases expression		 EXP 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of DERL1 protein] CTD PMID:30980806 NCBI chr 7:89,404,413...89,427,095
Ensembl chr 7:89,404,417...89,427,145 		JBrowse link
G Derl3 derlin 3 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of DERL3 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of DERL3 mRNA] CTD PMID:33484791 NCBI chr20:12,754,490...12,768,454
Ensembl chr20:12,763,543...12,767,027 		JBrowse link
G Des desmin multiple interactions
increases expression		 EXP Mycophenolic Acid inhibits the reaction [Streptozocin results in increased expression of DES protein]; Valsartan inhibits the reaction [Streptozocin results in increased expression of DES protein] CTD PMID:12197670 PMID:17624267 NCBI chr 9:76,850,979...76,858,695
Ensembl chr 9:76,850,982...76,858,699 		JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 multiple interactions ISO [Dietary Fats co-treated with Streptozocin] results in increased expression of DGAT1 mRNA; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of DGAT1 mRNA] CTD PMID:33812996 NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299 		JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 multiple interactions EXP [[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in decreased expression of DGAT2 mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of DGAT2 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of DGAT2 mRNA CTD PMID:35786680 NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428 		JBrowse link
G Dgkh diacylglycerol kinase, eta multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of DGKH mRNA CTD PMID:20665664 NCBI chr15:53,981,079...54,150,470
Ensembl chr15:53,991,481...54,150,706 		JBrowse link
G Dhrs7 dehydrogenase/reductase 7 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of DHRS7 mRNA CTD PMID:25905778 NCBI chr 6:91,332,259...91,347,856
Ensembl chr 6:91,251,323...91,347,892 		JBrowse link
G Dhrs9 dehydrogenase/reductase 9 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of DHRS9 mRNA CTD PMID:29127188 NCBI chr 3:54,147,834...54,170,052
Ensembl chr 3:54,147,803...54,220,241 		JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein multiple interactions ISO [Streptozocin co-treated with NQO1 protein mutant form] results in increased secretion of DIABLO protein CTD PMID:23458895 NCBI chr12:33,055,784...33,070,401
Ensembl chr12:33,055,263...33,070,387 		JBrowse link
G Dio1 iodothyronine deiodinase 1 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of DIO1 mRNA CTD PMID:25905778 NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970 		JBrowse link
G Dio3 iodothyronine deiodinase 3 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of DIO3 mRNA CTD PMID:33484791 NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660 		JBrowse link
G Dlat dihydrolipoamide S-acetyltransferase multiple interactions
increases expression		 EXP Trientine inhibits the reaction [Streptozocin results in increased expression of DLAT protein] CTD PMID:21136691 NCBI chr 8:50,979,151...51,004,435
Ensembl chr 8:50,978,051...51,004,479 		JBrowse link
G Dld dihydrolipoamide dehydrogenase increases expression
multiple interactions		 EXP Streptozocin results in increased expression of DLD protein
Trientine inhibits the reaction [Streptozocin results in increased expression of DLD protein]		 CTD PMID:21136691 NCBI chr 6:47,904,153...47,924,814
Ensembl chr 6:47,903,914...47,924,795 		JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 multiple interactions
decreases expression		 EXP Ibuprofen inhibits the reaction [Streptozocin results in decreased expression of DLG4 protein]; Memantine inhibits the reaction [Streptozocin results in decreased expression of DLG4 protein] CTD PMID:24333387 NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153 		JBrowse link
G Dlgap2 DLG associated protein 2 multiple interactions
decreases expression		 EXP Ibuprofen inhibits the reaction [Streptozocin results in decreased expression of DLGAP2 mRNA]; Memantine inhibits the reaction [Streptozocin results in decreased expression of DLGAP2 mRNA] CTD PMID:24333387 NCBI chr16:74,786,771...75,496,402
Ensembl chr16:74,791,509...75,496,407 		JBrowse link
G Dlst dihydrolipoamide S-succinyltransferase multiple interactions
increases expression		 EXP Trientine inhibits the reaction [Streptozocin results in increased expression of DLST protein] CTD PMID:19634143 PMID:21136691 NCBI chr 6:104,758,511...104,783,296
Ensembl chr 6:104,758,631...104,783,296 		JBrowse link
G Dmbt1 deleted in malignant brain tumors 1 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of DMBT1 mRNA CTD PMID:25905778 NCBI chr 1:185,617,469...185,696,476
Ensembl chr 1:185,617,294...185,696,478 		JBrowse link
G Dmbt1l1 deleted in malignant brain tumors 1 like 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of CDCP3 mRNA CTD PMID:33484791 NCBI chr 1:185,949,897...186,084,340
Ensembl chr 1:185,949,881...186,084,338 		JBrowse link
G Dnah5 dynein, axonemal, heavy chain 5 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of DNAH5 mRNA CTD PMID:33484791 NCBI chr 2:78,937,788...79,255,551
Ensembl chr 2:78,937,800...79,254,890 		JBrowse link
G Dnm1l dynamin 1-like multiple interactions
increases expression		 EXP
ISO		 ferulic acid inhibits the reaction [Streptozocin results in increased expression of DNM1L protein]
[Dietary Fats co-treated with Streptozocin] results in increased expression of DNM1L mRNA		 CTD PMID:31029786 PMID:33812996 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482 		JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions
decreases expression		 ISO
EXP		 [Streptozocin co-treated with Dietary Fats] results in increased expression of DNMT1 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of DNMT1 protein; Folic Acid deficiency promotes the reaction [Streptozocin results in decreased expression of DNMT1 mRNA]; Folic Acid inhibits the reaction [Streptozocin results in decreased expression of DNMT1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in decreased expression of DNMT1 mRNA]
[Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in decreased expression of DNMT1 mRNA]; [Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in decreased expression of DNMT1 protein]; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in decreased expression of DNMT1 mRNA]]; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in decreased expression of DNMT1 protein]]		 CTD PMID:28422052 PMID:29127188 PMID:36547818 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of DNMT3A mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of DNMT3A protein CTD PMID:29127188 NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687 		JBrowse link
G Dnmt3b DNA methyltransferase 3 beta multiple interactions
increases expression		 ISO
EXP		 [Streptozocin co-treated with Dietary Fats] results in increased expression of DNMT3B mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of DNMT3B protein
Streptozocin results in increased expression of DNMT3B mRNA		 CTD PMID:29127188 PMID:37081038 NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124 		JBrowse link
G Dpp4 dipeptidylpeptidase 4 increases response to substance
decreases activity
decreases expression
increases expression		 EXP DPP4 results in increased susceptibility to Streptozocin
Streptozocin results in decreased activity of DPP4 protein
Streptozocin results in decreased expression of DPP4 protein
Streptozocin results in increased expression of DPP4 mRNA		 CTD PMID:16045816 PMID:18931022 NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901 		JBrowse link
G Ece1 endothelin converting enzyme 1 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of ECE1 mRNA
Triterpenes inhibits the reaction [Streptozocin results in increased expression of ECE1 mRNA]		 CTD PMID:19000375 NCBI chr 5:150,077,679...150,179,375
Ensembl chr 5:150,077,644...150,179,371 		JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 increases expression EXP Streptozocin results in increased expression of ECHS1 protein CTD PMID:21136691 NCBI chr 1:194,895,036...194,903,863
Ensembl chr 1:194,895,036...194,903,884 		JBrowse link
G Edaradd EDAR associated via death domain multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of EDARADD mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of EDARADD mRNA] CTD PMID:33484791 NCBI chr17:85,866,629...85,910,612
Ensembl chr17:85,656,905...85,910,447 		JBrowse link
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 increases expression EXP Streptozocin results in increased expression of EDEM1 mRNA CTD PMID:25905778 NCBI chr 4:141,797,631...141,829,717
Ensembl chr 4:141,797,701...141,829,717 		JBrowse link
G Edem3 ER degradation enhancing alpha-mannosidase like protein 3 multiple interactions ISO [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of EDEM3 mRNA]; [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of EDEM3 protein]; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of EDEM3 mRNA; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of EDEM3 protein CTD PMID:38282657 NCBI chr13:63,858,282...63,920,538
Ensembl chr13:63,858,716...63,920,523 		JBrowse link
G Edn1 endothelin 1 multiple interactions
increases expression		 EXP
ISO		 Bezafibrate inhibits the reaction [Streptozocin results in increased expression of EDN1 mRNA]; Triterpenes inhibits the reaction [Streptozocin results in increased expression of EDN1 protein]
Streptozocin results in increased expression of EDN1 mRNA; Streptozocin results in increased expression of EDN1 protein
diphenyleneiodonium inhibits the reaction [Streptozocin promotes the reaction [EDN1 protein results in increased chemical synthesis of Inositol 1,4,5-Trisphosphate]]; Streptozocin promotes the reaction [EDN1 protein results in increased chemical synthesis of Inositol 1,4,5-Trisphosphate]		 CTD PMID:12458661 PMID:12967931 PMID:19000375 PMID:20691780 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Efna3 ephrin A3 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of EFNA3 mRNA CTD PMID:33484791 NCBI chr 2:174,729,192...174,738,111
Ensembl chr 2:174,729,764...174,738,736 		JBrowse link
G Efnb2 ephrin B2 affects expression ISO Streptozocin affects the expression of EFNB2 mRNA CTD PMID:26073000 NCBI chr16:80,783,389...80,827,420
Ensembl chr16:80,783,417...80,824,391 		JBrowse link
G Egfr epidermal growth factor receptor increases expression EXP Streptozocin results in increased expression of EGFR mRNA CTD PMID:37081038 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase increases expression EXP Streptozocin results in increased expression of EHHADH mRNA CTD PMID:25905778 NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions
increases phosphorylation		 ISO
EXP		 [Dietary Fats co-treated with Streptozocin] results in increased expression of EIF2AK3 protein; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of EIF2AK3 protein]
[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of EIF2AK3 protein; Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of EIF2AK3 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of EIF2AK3 protein]; Vitamin B 12 inhibits the reaction [Streptozocin results in increased phosphorylation of EIF2AK3 protein]		 CTD PMID:33812996 PMID:34801538 PMID:38049026 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha multiple interactions ISO [Dietary Fats co-treated with Streptozocin] results in increased phosphorylation of EIF2S1 protein; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased phosphorylation of EIF2S1 protein] CTD PMID:33812996 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225 		JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions
increases expression		 EXP vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of EIF4EBP1 mRNA] CTD PMID:16684804 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984 		JBrowse link
G Elk1 ETS transcription factor ELK1 increases phosphorylation EXP Streptozocin results in increased phosphorylation of ELK1 protein CTD PMID:12642375 NCBI chr  X:1,138,826...1,155,713
Ensembl chr  X:1,139,756...1,155,713 		JBrowse link
G Elovl7 ELOVL fatty acid elongase 7 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of ELOVL7 mRNA CTD PMID:29127188 NCBI chr 2:39,789,229...39,858,579
Ensembl chr 2:39,789,250...39,856,845 		JBrowse link
G Eno1 enolase 1 increases expression EXP Streptozocin results in increased expression of ENO1 protein CTD PMID:24924950 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336 		JBrowse link
G Eno1-ps1 enolase 1, pseudogene 1 decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of ENO1-PS1 protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of ENO1-PS1 protein]		 CTD PMID:19634143 NCBI chr 3:57,576,643...57,578,321
Ensembl chr 3:57,576,709...57,578,013 		JBrowse link
G Eno2 enolase 2 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of ENO2 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ENO2 mRNA] CTD PMID:33484791 NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980 		JBrowse link
G Enpep glutamyl aminopeptidase multiple interactions
increases activity		 EXP
ISO		 [resveratrol co-treated with Streptozocin] results in decreased expression of ENPEP mRNA
Streptozocin results in increased activity of ENPEP protein		 CTD PMID:25905778 PMID:28468961 NCBI chr 2:217,781,985...217,851,947
Ensembl chr 2:217,782,005...217,851,947 		JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of ENPP2 mRNA CTD PMID:25905778 NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827 		JBrowse link
G Ep300 E1A binding protein p300 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of EP300 mRNA
3-aminobenzamide inhibits the reaction [Streptozocin results in increased expression of EP300 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of EP300 mRNA]		 CTD PMID:22228707 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088 		JBrowse link
G Epcam epithelial cell adhesion molecule multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of EPCAM mRNA CTD PMID:25905778 NCBI chr 6:6,880,142...6,896,103
Ensembl chr 6:6,878,237...6,896,127 		JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of EPHX1 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of EPHX1 protein]		 CTD PMID:19634143 NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235 		JBrowse link
G Ephx2 epoxide hydrolase 2 increases expression
multiple interactions
decreases response to substance		 EXP
ISO		 Streptozocin results in increased expression of EPHX2 protein
EPHX2 gene mutant form inhibits the reaction [Streptozocin results in increased activity of RELA protein]; EPHX2 gene mutant form inhibits the reaction [Streptozocin results in increased secretion of CCL2 protein]
EPHX2 gene mutant form results in decreased susceptibility to Streptozocin		 CTD PMID:21832210 PMID:23611540 NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615 		JBrowse link
G Epo erythropoietin multiple interactions
decreases expression
increases expression		 EXP [Dietary Fats co-treated with Streptozocin] results in decreased expression of EPO protein; dapagliflozin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of EPO protein]; Enalapril inhibits the reaction [Streptozocin results in increased expression of EPO mRNA]; Simvastatin inhibits the reaction [Streptozocin results in decreased expression of EPO protein]; Simvastatin inhibits the reaction [Streptozocin results in increased expression of EPO mRNA] CTD PMID:19958114 PMID:20821229 PMID:34391751 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946 		JBrowse link
G Epor erythropoietin receptor multiple interactions
decreases expression
increases expression		 EXP Enalapril inhibits the reaction [Streptozocin results in increased expression of EPOR mRNA]; Enalapril inhibits the reaction [Streptozocin results in increased expression of EPOR protein]; Simvastatin inhibits the reaction [Streptozocin results in decreased expression of EPOR protein]; Simvastatin inhibits the reaction [Streptozocin results in increased expression of EPOR mRNA]
Streptozocin results in increased expression of EPOR mRNA; Streptozocin results in increased expression of EPOR protein		 CTD PMID:19958114 PMID:20821229 NCBI chr 8:20,489,678...20,494,257
Ensembl chr 8:20,489,678...20,494,257 		JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit increases expression
multiple interactions		 EXP Streptozocin results in increased expression of ERCC1 mRNA; Streptozocin results in increased expression of ERCC1 protein
3-aminobenzamide inhibits the reaction [Streptozocin results in increased expression of ERCC1 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of ERCC1 mRNA]		 CTD PMID:22228707 NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963 		JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit multiple interactions
increases expression		 EXP 3-aminobenzamide inhibits the reaction [Streptozocin results in increased expression of ERCC4 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of ERCC4 mRNA]
Streptozocin results in increased expression of ERCC4 mRNA; Streptozocin results in increased expression of ERCC4 protein		 CTD PMID:22228707 NCBI chr10:2,416,259...2,448,364
Ensembl chr10:2,419,038...2,448,369 		JBrowse link
G Ermap erythroblast membrane associated protein (Scianna blood group) multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of ERMAP mRNA CTD PMID:33484791 NCBI chr 5:132,788,847...132,803,030
Ensembl chr 5:132,789,991...132,802,847 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions
increases expression		 EXP
ISO		 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of ERN1 protein modified form]; [Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of ERN1 protein; Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of ERN1 protein]
[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of ERN1 protein; aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of ERN1 protein]		 CTD PMID:20399799 PMID:34801538 PMID:35961541 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029 		JBrowse link
G Ern2 endoplasmic reticulum to nucleus signaling 2 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of ERN2 protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ERN2 protein] CTD PMID:33484791 NCBI chr 1:176,726,454...176,743,289
Ensembl chr 1:176,726,454...176,743,289 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
decreases expression
increases expression		 ISO
EXP		 bisphenol A inhibits the reaction [Streptozocin results in decreased expression of ESR1 mRNA]; Ethinyl Estradiol inhibits the reaction [Streptozocin results in decreased expression of ESR1 mRNA]; octylphenol inhibits the reaction [Streptozocin results in decreased expression of ESR1 mRNA]
[Streptozocin co-treated with Tobacco Smoke Pollution] results in increased expression of ESR1 protein
Streptozocin results in increased expression of ESR1		 CTD PMID:24781736 PMID:30421503 PMID:32469605 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Esr2 estrogen receptor 2 multiple interactions
decreases expression		 ISO bisphenol A inhibits the reaction [Streptozocin results in decreased expression of ESR2 mRNA]; bisphenol A inhibits the reaction [Streptozocin results in decreased expression of ESR2 protein]; ESR2 protein affects the reaction [Raloxifene Hydrochloride inhibits the reaction [Streptozocin results in decreased secretion of MMP2 protein]]; Ethinyl Estradiol inhibits the reaction [Streptozocin results in decreased expression of ESR2 mRNA]; octylphenol inhibits the reaction [Streptozocin results in decreased expression of ESR2 mRNA]
Streptozocin results in decreased expression of ESR2 mRNA; Streptozocin results in decreased expression of ESR2 protein		 CTD PMID:23471663 PMID:24781736 PMID:35051763 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Etfa electron transfer flavoprotein subunit alpha decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of ETFA protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of ETFA protein]		 CTD PMID:19634143 NCBI chr 8:55,835,115...55,891,890
Ensembl chr 8:55,835,134...55,891,969 		JBrowse link
G Etfb electron transfer flavoprotein subunit beta decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of ETFB protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of ETFB protein]		 CTD PMID:19634143 NCBI chr 1:93,851,908...93,866,072
Ensembl chr 1:93,851,858...93,866,068 		JBrowse link
G Etfdh electron transfer flavoprotein dehydrogenase affects expression ISO Streptozocin affects the expression of ETFDH mRNA CTD PMID:18583417 NCBI chr 2:164,740,547...164,762,754
Ensembl chr 2:164,729,749...164,762,745 		JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor multiple interactions
decreases expression		 ISO SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of ETS1 mRNA] CTD PMID:27629361 NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010 		JBrowse link
G Eya2 EYA transcriptional coactivator and phosphatase 2 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of EYA2 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of EYA2 mRNA] CTD PMID:33484791 NCBI chr 3:154,335,598...154,519,006
Ensembl chr 3:154,335,400...154,518,793 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of EZH2 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of EZH2 protein CTD PMID:29127188 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362 		JBrowse link
G F3 coagulation factor III, tissue factor decreases activity EXP Streptozocin results in decreased activity of F3 protein CTD PMID:32864810 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668 		JBrowse link
G Fabp4 fatty acid binding protein 4 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of FABP4 mRNA CTD PMID:29127188 NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578 		JBrowse link
G Fabp7 fatty acid binding protein 7 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of FABP7 mRNA CTD PMID:29127188 NCBI chr20:37,123,193...37,126,725
Ensembl chr20:37,123,193...37,126,880 		JBrowse link
G Fadd Fas associated via death domain multiple interactions
increases expression		 EXP Anthocyanins inhibits the reaction [Streptozocin results in increased expression of FADD protein] CTD PMID:28856781 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653 		JBrowse link
G Fads1 fatty acid desaturase 1 decreases expression EXP Streptozocin results in decreased expression of FADS1 mRNA CTD PMID:25246140 NCBI chr 1:206,827,724...206,842,734
Ensembl chr 1:206,827,765...206,842,734 		JBrowse link
G Fam184a family with sequence similarity 184, member A multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of FAM184A mRNA CTD PMID:33484791 NCBI chr20:32,934,424...33,056,626
Ensembl chr20:32,934,636...33,056,652 		JBrowse link
G Fars2 phenylalanyl-tRNA synthetase 2, mitochondrial affects expression ISO Streptozocin affects the expression of FARS2 mRNA CTD PMID:18583417 NCBI chr17:28,319,215...28,746,217
Ensembl chr17:28,319,280...28,746,337 		JBrowse link
G Fas Fas cell surface death receptor multiple interactions
increases expression		 EXP Anthocyanins inhibits the reaction [Streptozocin results in increased expression of FAS protein] CTD PMID:28856781 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Faslg Fas ligand multiple interactions
increases expression		 EXP Anthocyanins inhibits the reaction [Streptozocin results in increased expression of FASLG protein]; rosiglitazone inhibits the reaction [Streptozocin results in increased expression of FASLG mRNA]
Streptozocin results in increased expression of FASLG mRNA; Streptozocin results in increased expression of FASLG protein		 CTD PMID:21791967 PMID:28856781 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Fasn fatty acid synthase multiple interactions
decreases expression
increases expression		 EXP
ISO		 Allopurinol inhibits the reaction [Streptozocin results in increased expression of FASN mRNA]; Allopurinol inhibits the reaction [Streptozocin results in increased expression of FASN protein]; GHRL protein promotes the reaction [Streptozocin results in decreased expression of FASN mRNA]; INS protein inhibits the reaction [Streptozocin results in decreased expression of FASN mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of FASN mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of FASN protein]
Streptozocin results in increased expression of FASN mRNA; Streptozocin results in increased expression of FASN protein
[Dietary Fats co-treated with Streptozocin] results in decreased expression of FASN mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of FASN mRNA; Acrylamide inhibits the reaction [Streptozocin results in increased expression of FASN mRNA]; esculetin promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of FASN mRNA]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FASN mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FASN mRNA]		 CTD PMID:20219977 PMID:23647015 PMID:27769711 PMID:29988851 PMID:33812996 More... NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
G Faxc failed axon connections homolog, metaxin like GST domain containing multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of FAXC mRNA CTD PMID:33484791 NCBI chr 5:35,480,137...35,539,741
Ensembl chr 5:35,480,402...35,544,446 		JBrowse link
G Fbp1 fructose-bisphosphatase 1 increases activity
multiple interactions		 EXP Streptozocin results in increased activity of FBP1 protein
citronellol inhibits the reaction [Streptozocin results in increased activity of FBP1 protein]		 CTD PMID:26944432 NCBI chr17:2,207,271...2,230,076
Ensembl chr17:2,208,031...2,230,071 		JBrowse link
G Fbp2 fructose-bisphosphatase 2 multiple interactions ISO [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FBP2 protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of FBP2 protein CTD PMID:25446853 NCBI chr17:2,236,088...2,253,702
Ensembl chr17:2,236,336...2,253,698 		JBrowse link
G Fbxo32 F-box protein 32 increases expression
multiple interactions		 EXP
ISO		 Streptozocin results in increased expression of FBXO32 protein
4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of FBXO32 protein]		 CTD PMID:30635400 PMID:30980806 NCBI chr 7:89,731,428...89,764,997
Ensembl chr 7:89,730,232...89,765,436 		JBrowse link
G Fcer1g Fc epsilon receptor Ig multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of FCER1G mRNA CTD PMID:25905778 NCBI chr13:83,649,447...83,654,248
Ensembl chr13:83,649,449...83,671,443 		JBrowse link
G Fcgr2a Fc gamma receptor 2A increases expression
multiple interactions		 EXP Streptozocin results in increased expression of FCGR3 mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of FCGR3 mRNA]		 CTD PMID:16684804 NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967 		JBrowse link
G Fgf17 fibroblast growth factor 17 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in increased expression of FGF17 mRNA; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in increased expression of FGF17 mRNA] CTD PMID:32303808 NCBI chr15:45,711,498...45,717,622
Ensembl chr15:45,711,998...45,717,063 		JBrowse link
G Fgf19 fibroblast growth factor 19 multiple interactions ISO [Dietary Fats co-treated with Streptozocin] results in increased expression of FGF15 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of FGF15 protein CTD PMID:29382564 NCBI chr 1:200,056,526...200,060,980
Ensembl chr 1:200,056,644...200,060,287 		JBrowse link
G Fgf21 fibroblast growth factor 21 multiple interactions
affects response to substance		 ISO [Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of FGF21 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of FGF21 mRNA; FGF21 protein affects the reaction [Streptozocin results in increased expression of AIFM1]; FGF21 protein affects the reaction [Streptozocin results in increased expression of CASP12 protein modified form]; FGF21 protein affects the reaction [Streptozocin results in increased expression of DDIT3]; Glucagon analog promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of FGF21 protein]
FGF21 protein affects the susceptibility to Streptozocin		 CTD PMID:23499715 PMID:29127188 PMID:29988851 NCBI chr 1:96,083,360...96,084,911
Ensembl chr 1:96,083,441...96,090,454 		JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 multiple interactions
decreases expression		 EXP rosiglitazone inhibits the reaction [Streptozocin results in decreased expression of FGFR1] CTD PMID:24136780 NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350 		JBrowse link
G Fh fumarate hydratase affects expression ISO Streptozocin affects the expression of FH1 mRNA CTD PMID:18583417 NCBI chr13:87,524,331...87,550,215
Ensembl chr13:87,524,337...87,550,266 		JBrowse link
G Fis1 fission, mitochondrial 1 multiple interactions ISO [Dietary Fats co-treated with Streptozocin] results in increased expression of FIS1 mRNA CTD PMID:33812996 NCBI chr12:19,708,560...19,723,392
Ensembl chr12:19,708,558...19,723,377 		JBrowse link
G Fitm2 fat storage-inducing transmembrane protein 2 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of FITM2 mRNA CTD PMID:25905778 NCBI chr 3:152,141,346...152,147,858
Ensembl chr 3:152,141,346...152,147,858 		JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B multiple interactions
decreases expression		 ISO
EXP		 Streptozocin promotes the reaction [bisphenol A results in decreased expression of FKBP1B mRNA]; Streptozocin promotes the reaction [octylphenol results in decreased expression of FKBP1B mRNA]
Triterpenes inhibits the reaction [Streptozocin results in decreased expression of FKBP1B mRNA]; Triterpenes inhibits the reaction [Streptozocin results in decreased expression of FKBP1B protein]
Streptozocin results in decreased expression of FKBP1B mRNA; Streptozocin results in decreased expression of FKBP1B protein		 CTD PMID:19000375 PMID:29935216 NCBI chr 6:27,832,128...27,850,600
Ensembl chr 6:27,838,802...27,848,653 		JBrowse link
G Flacc1 flagellum associated containing coiled-coil domains 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of FLACC1 mRNA CTD PMID:33484791 NCBI chr 9:60,315,581...60,343,692
Ensembl chr 9:60,315,582...60,343,648 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 multiple interactions
increases expression		 EXP
ISO		 Simvastatin inhibits the reaction [Streptozocin results in increased expression of FLT1 mRNA]; Simvastatin inhibits the reaction [Streptozocin results in increased phosphorylation of and results in increased expression of FLT1 protein]; Streptozocin results in increased phosphorylation of and results in increased expression of FLT1 protein CTD PMID:20821229 PMID:26073000 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626 		JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 increases expression EXP Streptozocin results in increased expression of FMO2 mRNA CTD PMID:25905778 NCBI chr13:75,221,149...75,244,377
Ensembl chr13:75,224,402...75,244,308 		JBrowse link
G Fmo4 flavin containing dimethylaniline monoxygenase 4 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of FMO4 mRNA CTD PMID:25905778 NCBI chr13:75,154,683...75,172,874
Ensembl chr13:75,154,684...75,172,874 		JBrowse link
G Fn1 fibronectin 1 increases expression
multiple interactions		 EXP
ISO		 Streptozocin results in increased expression of FN1; Streptozocin results in increased expression of FN1 mRNA; Streptozocin results in increased expression of FN1 protein
3-aminobenzamide inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; [Streptozocin co-treated with Cadmium] results in increased expression of FN1 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein; Aspirin inhibits the reaction [Streptozocin results in increased expression of FN1]; benazepril inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; Carvedilol inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein]; esculetin inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; esculetin inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; fasudil inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; fenugreek seed meal inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; Gallic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of FN1 protein]; Organoselenium Compounds inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; stannous mesoporphyrin inhibits the reaction [4-(4-(3-adamantan-1-ylureido)cyclohexyloxy)benzoic acid inhibits the reaction [Streptozocin results in increased expression of FN1 protein]]; Trientine inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; XLF-III-43 inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; Zinc inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]
[AM6545 co-treated with Perindopril] inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; [Dietary Fats co-treated with Streptozocin] results in increased expression of FN1 protein; [fatostatin co-treated with Streptozocin] results in increased expression of FN1 mRNA; [fatostatin co-treated with Streptozocin] results in increased expression of FN1 protein; [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of FN1 protein]; [Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of FN1 protein; AM6545 inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; AM6545 inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; CREB1 protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein]; CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FN1 protein]; HDAC3 protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein]; KLF15 gene mutant form inhibits the reaction [CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FN1 protein]]; KLF15 gene mutant form promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FN1 protein]; Perindopril inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; Perindopril inhibits the reaction [Streptozocin results in increased expression of FN1 protein]		 CTD PMID:11798618 PMID:12140129 PMID:14586741 PMID:16973718 PMID:19895808 More... NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression		 ISO formononetin inhibits the reaction [Streptozocin results in increased expression of FOS mRNA]; formononetin inhibits the reaction [Streptozocin results in increased expression of FOS protein]
Streptozocin results in increased expression of FOS mRNA; Streptozocin results in increased expression of FOS protein		 CTD PMID:35315182 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of FOSB mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of FOSB mRNA] CTD PMID:33484791 NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465 		JBrowse link
G Foxa2 forkhead box A2 multiple interactions EXP copper bis(3,5-diisopropylsalicylate) inhibits the reaction [Streptozocin results in decreased expression of FOXA2] CTD PMID:23795780 NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326 		JBrowse link
G Foxo1 forkhead box O1 multiple interactions
increases acetylation
decreases expression
decreases phosphorylation		 ISO
EXP		 [Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of FOXO1 protein; resveratrol inhibits the reaction [Streptozocin results in increased acetylation of FOXO1 protein]; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of FOXO1 protein]
[Dietary Fats co-treated with Streptozocin] affects the localization of FOXO1 protein; Butyric Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] affects the localization of FOXO1 protein]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] affects the localization of FOXO1 protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of FOXO1 mRNA]; Resveratrol inhibits the reaction [Streptozocin results in increased phosphorylation of and results in decreased activity of FOXO1 protein]; Streptozocin results in increased phosphorylation of and results in decreased activity of FOXO1 protein; Tribulus extract inhibits the reaction [Streptozocin results in decreased phosphorylation of FOXO1 protein]		 CTD PMID:22733486 PMID:24889822 PMID:26522834 PMID:27270450 PMID:36627075 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790 		JBrowse link
G Foxo3 forkhead box O3 decreases expression
increases expression
multiple interactions		 EXP
ISO		 Streptozocin results in decreased expression of FOXO3 protein
Streptozocin results in increased expression of FOXO3 protein modified form
Streptozocin results in increased expression of FOXO3 protein; Streptozocin results in increased expression of FOXO3 protein modified form
[Streptozocin co-treated with Resveratrol co-treated with Ramipril] results in increased phosphorylation of FOXO3 protein; [Streptozocin co-treated with Resveratrol] results in increased phosphorylation of FOXO3 protein; Resveratrol inhibits the reaction [Streptozocin results in increased expression of FOXO3 protein]		 CTD PMID:17082237 PMID:18703049 PMID:23792339 PMID:31062909 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561 		JBrowse link
G Fshb follicle stimulating hormone subunit beta decreases expression
multiple interactions		 EXP
ISO		 Streptozocin results in decreased expression of FSHB protein
Sildenafil Citrate inhibits the reaction [Streptozocin results in decreased expression of FSHB protein]; vitexin inhibits the reaction [Streptozocin results in decreased expression of FSHB protein]
[Streptozocin co-treated with Fructose] results in decreased expression of FSHB protein; Acetates inhibits the reaction [[Streptozocin co-treated with Fructose] results in decreased expression of FSHB protein]		 CTD PMID:19931367 PMID:30365938 PMID:34656705 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370 		JBrowse link
G Fth1 ferritin heavy chain 1 multiple interactions ISO [Dietary Fats co-treated with Streptozocin] results in increased expression of FTH1 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of FTH1 mRNA; omaveloxolone analog promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FTH1 mRNA]; omaveloxolone promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FTH1 mRNA] CTD PMID:32410268 PMID:38483099 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424 		JBrowse link
G Ftl1 ferritin light chain 1 multiple interactions ISO [Dietary Fats co-treated with Streptozocin] results in increased expression of FTL1 protein CTD PMID:38483099 NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725
Ensembl chr10:95,936,387...95,939,725 		JBrowse link
G Fxyd2 FXYD domain-containing ion transport regulator 2 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of FXYD2 mRNA CTD PMID:25905778 NCBI chr 8:45,712,901...45,720,032
Ensembl chr 8:45,712,903...45,720,203 		JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions
decreases activity
increases activity
increases expression
decreases expression		 EXP
ISO		 4-hydroxyphenylethanol inhibits the reaction [Streptozocin results in increased activity of G6PC1 protein]; bis(maltolato)oxovanadium(IV) inhibits the reaction [Streptozocin results in increased expression of G6PC1 mRNA]; citronellol inhibits the reaction [Streptozocin results in increased activity of G6PC1 protein]; Glyburide inhibits the reaction [Streptozocin results in increased activity of G6PC1 protein]; Phlorhizin inhibits the reaction [Streptozocin results in increased expression of G6PC1 mRNA]; Plant Extracts inhibits the reaction [Streptozocin results in decreased activity of G6PC1 protein]; Plant Extracts inhibits the reaction [Streptozocin results in increased expression of G6PC1 mRNA]; plumbagin inhibits the reaction [Streptozocin results in increased activity of G6PC1 protein]; Polysaccharides inhibits the reaction [Streptozocin results in decreased activity of G6PC1 protein]; Tribulus extract inhibits the reaction [Streptozocin results in increased expression of G6PC1 protein]; Trientine inhibits the reaction [Streptozocin results in increased expression of G6PC1 protein]
Streptozocin results in increased expression of G6PC1 mRNA; Streptozocin results in increased expression of G6PC1 protein
Streptozocin results in decreased expression of G6PC1 mRNA
[1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of G6PC1 protein]; [Dietary Fats co-treated with Streptozocin] results in decreased activity of G6PC1 protein; [Dietary Fats co-treated with Streptozocin] results in increased expression of G6PC1 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of G6PC1 mRNA; Acrylamide inhibits the reaction [Streptozocin results in increased expression of G6PC1 mRNA]; esculetin promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of G6PC1 protein]; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of G6PC1 mRNA]		 CTD PMID:12446591 PMID:19634143 PMID:22960630 PMID:25446853 PMID:25641191 More... NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804 		JBrowse link
G G6pc3 glucose 6 phosphatase catalytic subunit 3 decreases activity
multiple interactions		 EXP Streptozocin results in decreased activity of G6PC3 protein
Glyburide inhibits the reaction [Streptozocin results in decreased activity of G6PC3 protein]; Hesperidin inhibits the reaction [Streptozocin results in decreased activity of G6PC3 protein]		 CTD PMID:31345080 NCBI chr10:87,146,987...87,151,223
Ensembl chr10:87,146,901...87,151,221 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase multiple interactions
decreases activity
decreases expression		 EXP
ISO		 2-tert-butylhydroquinone inhibits the reaction [Streptozocin results in decreased expression of G6PD mRNA]; 2-tert-butylhydroquinone inhibits the reaction [Streptozocin results in decreased expression of G6PD protein]; 4-hydroxyphenylethanol inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]; [Dietary Fats co-treated with Streptozocin] results in decreased activity of G6PD protein; [Phytic Acid co-treated with Inositol] inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]; [Streptozocin co-treated with Cadmium] results in decreased activity of G6PD protein; [Streptozocin co-treated with Niacinamide] affects the activity of G6PD protein; arjunolic acid inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]; citronellol inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]; G6PD protein promotes the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; G6PD protein promotes the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; geraniol inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]; Gliclazide inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]; Glyburide inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]; Hesperidin inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased activity of G6PD protein]; nerolidol inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of G6PD protein]; NFE2L2 protein inhibits the reaction [Streptozocin results in decreased expression of G6PD mRNA]; NFE2L2 protein inhibits the reaction [Streptozocin results in decreased expression of G6PD protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] affects the activity of G6PD protein]
[Streptozocin co-treated with Dietary Fats] results in decreased activity of G6PD protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased activity of G6PD protein]
Streptozocin results in decreased expression of G6PD mRNA; Streptozocin results in decreased expression of G6PD protein		 CTD PMID:19059388 PMID:19133311 PMID:19682444 PMID:24923654 PMID:25641191 More... NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G Gabra4 gamma-aminobutyric acid type A receptor subunit alpha 4 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of GABRA4 mRNA CTD PMID:33484791 NCBI chr14:36,590,782...36,667,724
Ensembl chr14:36,590,782...36,665,844 		JBrowse link
G Gabrr1 gamma-aminobutyric acid type A receptor subunit rho 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of GABRR1 mRNA; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of GABRR1 mRNA] CTD PMID:32303808 NCBI chr 5:47,524,151...47,561,228
Ensembl chr 5:47,524,151...47,561,228 		JBrowse link
G Gad1 glutamate decarboxylase 1 multiple interactions
decreases expression		 EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of GAD1 protein; Curcumin inhibits the reaction [Streptozocin results in decreased expression of GAD1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in decreased expression of GAD1 mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of GAD1 protein] CTD PMID:23267840 PMID:35085591 NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333 		JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta multiple interactions EXP
ISO		 [resveratrol co-treated with Streptozocin] results in increased expression of GADD45B mRNA
[Streptozocin co-treated with Dietary Fats] results in increased expression of GADD45B mRNA		 CTD PMID:25905778 PMID:29127188 NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046 		JBrowse link
G Galt galactose-1-phosphate uridylyltransferase decreases expression EXP Streptozocin results in decreased expression of GALT mRNA CTD PMID:25905778 NCBI chr 5:56,927,039...56,930,284
Ensembl chr 5:56,926,724...56,930,265 		JBrowse link
G Gas6 growth arrest specific 6 increases expression EXP Streptozocin results in increased expression of GAS6 protein CTD PMID:12644472 NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904 		JBrowse link
G Gatm glycine amidinotransferase multiple interactions
decreases expression		 EXP Trientine inhibits the reaction [Streptozocin results in decreased expression of GATM protein] CTD PMID:19634143 NCBI chr 3:109,658,919...109,675,508
Ensembl chr 3:109,658,951...109,684,129 		JBrowse link
G Gcg glucagon multiple interactions
decreases expression		 EXP [Dietary Fats co-treated with Streptozocin] results in increased expression of GCG protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of GCG mRNA; Butyric Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GCG protein]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GCG protein]; rosiglitazone inhibits the reaction [Streptozocin results in decreased expression of GCG mRNA]; Sitagliptin Phosphate inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GCG mRNA] CTD PMID:18998217 PMID:23466488 PMID:27270450 NCBI chr 3:47,113,914...47,122,958
Ensembl chr 3:47,113,914...47,122,929 		JBrowse link
G Gck glucokinase multiple interactions
decreases expression		 ISO
EXP		 [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GCK protein]; [Dietary Fats co-treated with Streptozocin] results in decreased activity of GCK protein; [Dietary Fats co-treated with Streptozocin] results in decreased expression of GCK mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of GCK protein; [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of GCK protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of GCK mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of GCK protein; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GCK mRNA]
[Dietary Fats co-treated with Streptozocin] results in decreased activity of GCK protein; [Dietary Fats co-treated with Streptozocin] results in decreased expression of GCK mRNA; nerolidol inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of GCK protein]; Plant Extracts inhibits the reaction [Streptozocin results in decreased expression of GCK mRNA]; repaglinide analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GCK mRNA]; repaglinide inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GCK mRNA]		 CTD PMID:25446853 PMID:26522834 PMID:27038876 PMID:27769711 PMID:29127188 More... NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions
decreases expression		 EXP
ISO		 [Streptozocin co-treated with Niacinamide] results in decreased expression of GCLC mRNA; [Streptozocin co-treated with Niacinamide] results in decreased expression of GCLC protein; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of GCLC mRNA]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of GCLC protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GCLC mRNA]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GCLC protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GCLC mRNA]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GCLC protein]
[Dietary Fats co-treated with Streptozocin] results in decreased expression of GCLC mRNA; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GCLC mRNA]
Streptozocin results in decreased expression of GCLC mRNA; Streptozocin results in decreased expression of GCLC protein		 CTD PMID:21439372 PMID:33359794 PMID:33639173 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions ISO [Dietary Fats co-treated with Streptozocin] results in decreased expression of GCLM mRNA CTD PMID:33359794 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Gcnt2 glucosaminyl (N-acetyl) transferase 2 increases expression EXP Streptozocin results in increased expression of GCNT2 mRNA CTD PMID:25905778 NCBI chr17:23,796,859...23,901,625
Ensembl chr17:23,796,859...23,901,611 		JBrowse link
G Gda guanine deaminase increases expression EXP Streptozocin results in increased expression of GDA mRNA CTD PMID:25905778 NCBI chr 1:218,903,045...218,982,360
Ensembl chr 1:218,906,815...218,982,416 		JBrowse link
G Gdnf glial cell derived neurotrophic factor multiple interactions
decreases expression		 EXP Vitamin B 12 inhibits the reaction [Streptozocin results in decreased expression of GDNF protein] CTD PMID:38049026 NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209 		JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions
increases expression
decreases expression		 EXP
ISO		 Ibuprofen inhibits the reaction [Streptozocin results in increased expression of GFAP mRNA]; Ibuprofen inhibits the reaction [Streptozocin results in increased expression of GFAP protein]; Memantine inhibits the reaction [Streptozocin results in increased expression of GFAP mRNA]; Memantine inhibits the reaction [Streptozocin results in increased expression of GFAP protein]; Vitamin B 12 inhibits the reaction [Streptozocin results in increased expression of GFAP protein]
Streptozocin results in increased expression of GFAP mRNA; Streptozocin results in increased expression of GFAP protein
Streptozocin results in decreased expression of GFAP protein
Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of GFAP protein]; Physostigmine inhibits the reaction [Streptozocin results in decreased expression of GFAP protein]		 CTD PMID:24333387 PMID:28499986 PMID:38049026 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589 		JBrowse link
G Gfm1 G elongation factor, mitochondrial 1 affects expression ISO Streptozocin affects the expression of GFM1 mRNA CTD PMID:18583417 NCBI chr 2:151,700,573...151,745,477
Ensembl chr 2:151,700,564...151,745,471 		JBrowse link
G Ggt1 gamma-glutamyltransferase 1 decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of GGT1 protein
[resveratrol co-treated with Streptozocin] results in increased expression of GGT1 mRNA; Trientine inhibits the reaction [Streptozocin results in decreased expression of GGT1 protein]		 CTD PMID:19634143 PMID:25905778 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442 		JBrowse link
G Ghr growth hormone receptor multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of GHR mRNA CTD PMID:25905778 NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735 		JBrowse link
G Ghrl ghrelin and obestatin prepropeptide multiple interactions EXP GHRL protein promotes the reaction [Streptozocin results in decreased expression of CARTPT mRNA]; GHRL protein promotes the reaction [Streptozocin results in decreased expression of FASN mRNA]; GHRL protein promotes the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA] CTD PMID:20219977 NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621 		JBrowse link
G Gk glycerol kinase decreases expression
multiple interactions		 EXP
ISO		 Streptozocin results in decreased expression of GK mRNA
[Dietary Fats co-treated with Streptozocin] results in increased expression of GK mRNA; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GK mRNA]		 CTD PMID:25905778 PMID:33812996 NCBI chr  X:50,162,089...50,238,707
Ensembl chr  X:50,163,123...50,238,631 		JBrowse link
G Glb1 galactosidase, beta 1 increases expression
multiple interactions		 ISO Streptozocin results in increased expression of GLB1 protein
2-amino-6-boronohexanoic acid inhibits the reaction [Streptozocin results in increased expression of GLB1 protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of GLB1 protein; ARG1 gene mutant form inhibits the reaction [Streptozocin results in increased expression of GLB1 protein]		 CTD PMID:29673160 PMID:38483099 NCBI chr 8:114,085,508...114,158,127
Ensembl chr 8:114,085,508...114,158,127 		JBrowse link
G Glis1 GLIS family zinc finger 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of GLIS1 mRNA CTD PMID:33484791 NCBI chr 5:122,222,155...122,412,141
Ensembl chr 5:122,222,128...122,412,141 		JBrowse link
G Glo1 glyoxalase 1 multiple interactions EXP [Streptozocin co-treated with Niacinamide] results in decreased activity of GLO1 protein; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of GLO1 protein]; resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of GLO1 protein] CTD PMID:21439372 NCBI chr20:8,663,617...8,681,661
Ensembl chr20:8,662,801...8,681,649 		JBrowse link
G Glp1r glucagon-like peptide 1 receptor multiple interactions EXP [Fructose co-treated with Streptozocin] results in decreased expression of GLP1R mRNA; Ghrelin inhibits the reaction [[Fructose co-treated with Streptozocin] results in decreased expression of GLP1R mRNA] CTD PMID:31468622 NCBI chr20:8,972,004...9,010,241
Ensembl chr20:8,972,004...9,010,241 		JBrowse link
G Glud1 glutamate dehydrogenase 1 multiple interactions EXP [Dietary Fats co-treated with Streptozocin] results in decreased expression of GLUD1 mRNA; repaglinide analog affects the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GLUD1 mRNA]; repaglinide inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GLUD1 mRNA] CTD PMID:35702883 NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957 		JBrowse link
G Glul glutamate-ammonia ligase multiple interactions
decreases expression		 EXP [resveratrol co-treated with Streptozocin] results in increased expression of GLUL mRNA; resveratrol inhibits the reaction [Streptozocin results in decreased expression of GLUL mRNA]; resveratrol inhibits the reaction [Streptozocin results in decreased expression of GLUL protein]
Streptozocin results in decreased expression of GLUL mRNA; Streptozocin results in decreased expression of GLUL protein		 CTD PMID:25905778 PMID:26677078 NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108 		JBrowse link
G Gna11 G protein subunit alpha 11 multiple interactions
increases expression		 EXP acetovanillone inhibits the reaction [Streptozocin results in increased expression of GNA11 protein]; CAT protein inhibits the reaction [Streptozocin results in increased expression of GNA11 protein] CTD PMID:20691780 NCBI chr 7:8,163,520...8,177,863
Ensembl chr 7:8,162,750...8,179,812 		JBrowse link
G Gnai2 G protein subunit alpha i2 multiple interactions
decreases expression		 EXP Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of GNAI2 protein]; diphenyleneiodonium inhibits the reaction [Streptozocin results in decreased expression of GNAI2 protein] CTD PMID:18441196 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979 		JBrowse link
G Gnai3 G protein subunit alpha i3 multiple interactions
decreases expression		 EXP Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of GNAI3 protein]; diphenyleneiodonium inhibits the reaction [Streptozocin results in decreased expression of GNAI3 protein] CTD PMID:18441196 NCBI chr 2:195,742,765...195,780,720
Ensembl chr 2:195,742,642...195,780,742 		JBrowse link
G Gnaq G protein subunit alpha q multiple interactions
increases expression		 EXP acetovanillone inhibits the reaction [Streptozocin results in increased expression of GNAQ protein]; CAT protein inhibits the reaction [Streptozocin results in increased expression of GNAQ protein] CTD PMID:20691780 NCBI chr 1:213,425,631...213,671,947
Ensembl chr 1:213,424,465...213,667,672 		JBrowse link
G Gngt1 G protein subunit gamma transducin 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of GNGT1 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of GNGT1 mRNA] CTD PMID:33484791 NCBI chr 4:32,006,267...32,009,252
Ensembl chr 4:32,006,267...32,009,252 		JBrowse link
G Gnmt glycine N-methyltransferase multiple interactions
increases activity
increases expression		 EXP Folic Acid inhibits the reaction [Streptozocin results in increased activity of GNMT protein]
Streptozocin results in increased expression of GNMT mRNA; Streptozocin results in increased expression of GNMT protein		 CTD PMID:16835399 NCBI chr 9:14,254,675...14,258,028
Ensembl chr 9:14,254,675...14,258,434 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 multiple interactions
increases secretion		 EXP
ISO		 [Resveratrol co-treated with Streptozocin] results in decreased expression of GOT1 mRNA; Atorvastatin inhibits the reaction [Streptozocin results in increased secretion of GOT1 protein]
[Streptozocin co-treated with Dietary Fats] results in increased expression of GOT1 protein; [Streptozocin co-treated with Dietary Fats] results in increased secretion of GOT1 protein; aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased secretion of GOT1 protein]; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of GOT1 protein]		 CTD PMID:25905778 PMID:30657622 PMID:35961541 PMID:37482253 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of GOT2 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of GOT2 protein]		 CTD PMID:19634143 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994 		JBrowse link
G Gpc1 glypican 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of GPC1 mRNA CTD PMID:29127188 NCBI chr 9:93,396,234...93,424,047
Ensembl chr 9:93,396,234...93,424,047 		JBrowse link
G Gpd1 glycerol-3-phosphate dehydrogenase 1 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of GPD1 mRNA CTD PMID:25905778 NCBI chr 7:130,842,526...130,851,530
Ensembl chr 7:130,844,138...130,851,529 		JBrowse link
G Gprc6a G protein-coupled receptor, class C, group 6, member A multiple interactions EXP [Dietary Fats co-treated with Streptozocin] results in decreased expression of GPRC6A mRNA; Warfarin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GPRC6A mRNA] CTD PMID:27488359 NCBI chr20:30,922,106...30,943,412
Ensembl chr20:30,922,106...30,943,412 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions
increases expression
increases activity
increases secretion		 EXP
ISO		 4-hydroxyisoleucine inhibits the reaction [Streptozocin results in increased expression of GPT protein]; [Dietary Fats co-treated with Streptozocin] results in increased activity of GPT protein; [Dietary Fats co-treated with Streptozocin] results in increased expression of GPT protein; [Streptozocin co-treated with Dietary Fats] results in increased activity of GPT protein; allyl isothiocyanate inhibits the reaction [Streptozocin promotes the reaction [Dietary Fats results in increased expression of GPT protein]]; Atorvastatin inhibits the reaction [Streptozocin results in increased secretion of GPT protein]; dapagliflozin inhibits the reaction [Streptozocin results in increased expression of GPT protein]; Ellagic Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GPT protein]; Eugenol inhibits the reaction [Streptozocin results in increased expression of GPT protein]; Ficusin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased activity of GPT protein]; Fungal Polysaccharides inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased activity of GPT protein]; Glyburide inhibits the reaction [Streptozocin results in increased activity of GPT protein]; mangiferin inhibits the reaction [Streptozocin results in increased activity of GPT protein]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased activity of GPT protein]; morin analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased activity of GPT protein]; naringenin inhibits the reaction [Streptozocin results in increased activity of GPT protein]; nerolidol inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased activity of GPT protein]; Pioglitazone inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased activity of GPT protein]; Plant Extracts inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased activity of GPT protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of GPT protein]; sodium tungstate(VI) inhibits the reaction [Streptozocin results in increased activity of GPT protein]; Streptozocin promotes the reaction [Dietary Fats results in increased expression of GPT protein]; Tribulus extract inhibits the reaction [Streptozocin results in increased activity of GPT protein]; Zinc Compounds inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased activity of GPT protein]
[Acrylamide co-treated with Streptozocin] results in increased activity of GPT protein; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of GPT protein; [omaveloxolone analog co-treated with Streptozocin co-treated with Dietary Fats] results in increased expression of GPT protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of GPT protein; [Streptozocin co-treated with Dietary Fats] results in increased secretion of GPT protein; aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased secretion of GPT protein]; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of GPT protein]; Metformin inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of GPT protein]; perilla seed oil inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of GPT protein]		 CTD PMID:11357483 PMID:24854284 PMID:24877639 PMID:26071184 PMID:27350165 More... NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions
decreases activity
decreases expression
increases expression		 ISO
EXP		 [Dietary Fats co-treated with Streptozocin] results in decreased expression of GPX1 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of GPX1 protein; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of GPX1 protein]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GPX1 mRNA]; Sodium Selenite inhibits the reaction [Streptozocin results in decreased activity of GPX1 protein]; Sodium Selenite inhibits the reaction [Streptozocin results in decreased expression of GPX1 mRNA]
Streptozocin results in increased expression of GPX1 protein
[[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in decreased expression of GPX1 mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of GPX1 mRNA; [Carbamazepine affects the susceptibility to [Dietary Fats co-treated with Streptozocin]] which results in decreased expression of GPX1 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of GPX1 mRNA; allyl methyl sulfide inhibits the reaction [Streptozocin results in decreased activity of GPX1 protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of GPX1 mRNA]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of GPX1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in decreased expression of GPX1 mRNA]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of GPX1 mRNA]; Trientine inhibits the reaction [Streptozocin results in increased expression of GPX1 protein]		 CTD PMID:18789669 PMID:19634143 PMID:23267840 PMID:24740756 PMID:30318971 More... NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Gpx2 glutathione peroxidase 2 multiple interactions EXP [[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in increased expression of GPX2 mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in increased expression of GPX2 mRNA; [Carbamazepine affects the susceptibility to [Dietary Fats co-treated with Streptozocin]] which results in increased expression of GPX2 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in increased expression of GPX2 mRNA; [Resveratrol co-treated with Streptozocin] results in increased expression of GPX2 mRNA CTD PMID:25905778 PMID:35786680 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877 		JBrowse link
G Gpx3 glutathione peroxidase 3 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of GPX3 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of GPX3 protein]		 CTD PMID:19634143 NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035 		JBrowse link
G Gpx4 glutathione peroxidase 4 multiple interactions ISO [Dietary Fats co-treated with Streptozocin] results in decreased expression of GPX4 mRNA; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GPX4 mRNA] CTD PMID:33359794 NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982 		JBrowse link
G Gramd2a GRAM domain containing 2A multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of GRAMD2A mRNA CTD PMID:33484791 NCBI chr 8:60,079,744...60,117,788
Ensembl chr 8:60,080,338...60,115,842 		JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist increases expression EXP Streptozocin results in increased expression of GREM1 mRNA CTD PMID:10744662 NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082 		JBrowse link
G Gria4 glutamate ionotropic receptor AMPA type subunit 4 multiple interactions
increases expression		 EXP Curcumin inhibits the reaction [Streptozocin results in increased expression of GRIA4 protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of GRIA4 protein] CTD PMID:23267840 NCBI chr 8:1,562,118...2,035,035
Ensembl chr 8:1,562,119...2,034,979 		JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 multiple interactions
increases expression		 EXP Curcumin inhibits the reaction [Streptozocin results in increased expression of GRIN1 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of GRIN1 protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of GRIN1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of GRIN1 protein]
Streptozocin results in increased expression of GRIN1 mRNA; Streptozocin results in increased expression of GRIN1 protein		 CTD PMID:23267840 NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603 		JBrowse link
G Grm5 glutamate metabotropic receptor 5 increases expression EXP Streptozocin results in increased expression of GRM5 protein CTD PMID:19840219 NCBI chr 1:141,310,069...141,884,980
Ensembl chr 1:141,312,368...141,882,274 		JBrowse link
G Gsdmd gasdermin D multiple interactions
increases expression
affects response to substance		 ISO
EXP		 [Dietary Fats co-treated with Streptozocin] results in increased expression of GSDMD mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of GSDMD protein; GSDMD protein affects the reaction [Streptozocin results in increased cleavage of CASP1 protein]; GSDMD protein affects the reaction [Streptozocin results in increased expression of IL18 protein]; GSDMD protein affects the reaction [Streptozocin results in increased expression of IL1B protein]; Hirudins inhibits the reaction [Streptozocin results in increased expression of and results in increased cleavage of GSDMD protein]; Hirudins inhibits the reaction [Streptozocin results in increased expression of GSDMD mRNA]; loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GSDMD mRNA]; loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GSDMD protein]; Streptozocin results in increased expression of and results in increased cleavage of GSDMD protein
GSDMD protein affects the susceptibility to Streptozocin
Streptozocin results in increased expression of GSDMD protein
scutellarin inhibits the reaction [Streptozocin results in increased expression of GSDMD protein]		 CTD PMID:34212273 PMID:37081038 PMID:37473909 NCBI chr 7:107,542,489...107,547,051
Ensembl chr 7:107,542,083...107,547,055 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases phosphorylation
multiple interactions
increases expression		 EXP
ISO		 Streptozocin results in decreased phosphorylation of GSK3B protein
[Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in decreased phosphorylation of GSK3B protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of GSK3B protein; Curcumin inhibits the reaction [Streptozocin results in decreased phosphorylation of GSK3B protein]; hesperetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of GSK3B protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in decreased phosphorylation of GSK3B protein]; Phosphocreatine inhibits the reaction [Streptozocin results in decreased phosphorylation of GSK3B protein]; Plant Extracts inhibits the reaction [[Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in decreased phosphorylation of GSK3B protein]; Plant Extracts inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of GSK3B protein]; Plant Extracts inhibits the reaction [Streptozocin results in increased expression of GSK3B mRNA]; Quercetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of GSK3B protein]; Streptozocin results in decreased expression of and results in decreased phosphorylation of GSK3B protein; STUB1 inhibits the reaction [Streptozocin results in decreased expression of and results in decreased phosphorylation of GSK3B protein]; Tribulus extract inhibits the reaction [Streptozocin results in decreased phosphorylation of GSK3B protein]
5-Methoxypsoralen inhibits the reaction [Streptozocin results in decreased phosphorylation of GSK3B protein]; [Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of GSK3B protein; [Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of GSK3B protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of GSK3B protein]; Metformin inhibits the reaction [Streptozocin results in decreased phosphorylation of GSK3B protein]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of GSK3B protein]; phillyrin inhibits the reaction [Streptozocin results in decreased phosphorylation of GSK3B protein]; Tadalafil inhibits the reaction [Streptozocin results in decreased phosphorylation of GSK3B protein]		 CTD PMID:25541178 PMID:27038876 PMID:28422052 PMID:31877369 PMID:33484791 More... NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Gspt2 G1 to S phase transition 2 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of GSPT2 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of GSPT2 mRNA] CTD PMID:33484791 NCBI chr  X:59,587,237...59,589,758
Ensembl chr  X:59,587,276...59,594,162 		JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions
decreases activity
increases activity
affects activity
decreases expression		 EXP [Carmustine results in decreased activity of GSR protein] which results in increased susceptibility to Streptozocin; [Dietary Fats co-treated with Streptozocin] results in decreased activity of GSR protein; [Niacinamide co-treated with Streptozocin] results in decreased activity of GSR protein; [Streptozocin co-treated with Dietary Fats] results in decreased activity of GSR protein; [Streptozocin co-treated with Niacinamide] results in decreased activity of GSR protein; [Zinc Sulfate results in increased abundance of Zinc] inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; Acetylcysteine inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; arjunolic acid inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; Bezafibrate inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; caryophyllene inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; Chromium inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; chromium tripicolinate inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; Ellagic Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of GSR protein]; Gallic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased activity of GSR protein]; geraniol inhibits the reaction [Streptozocin affects the activity of GSR protein]; Gliclazide inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in decreased activity of GSR protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of GSR protein]; Glyburide inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of GSR protein]; INS protein promotes the reaction [Streptozocin results in increased activity of GSR protein]; Metformin inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; morin inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; piperlongumine inhibits the reaction [Streptozocin results in decreased expression of GSR protein]; Resveratrol inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in decreased activity of GSR protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of GSR protein]; Rosiglitazone inhibits the reaction [Streptozocin promotes the reaction [Dietary Fats results in decreased activity of GSR protein]]; Sodium Selenite inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; Streptozocin promotes the reaction [Dietary Fats results in decreased activity of GSR protein]; Zinc inhibits the reaction [Streptozocin results in decreased activity of GSR protein] CTD PMID:11424224 PMID:15720826 PMID:17145126 PMID:19682444 PMID:19840221 More... NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Gsta1 glutathione S-transferase alpha 1 multiple interactions EXP [Streptozocin co-treated with iomeprol] results in increased expression of GSTA1 protein; palmidrol analog inhibits the reaction [[Streptozocin co-treated with iomeprol] results in increased expression of GSTA1 protein] CTD PMID:26474837 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121 		JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of GSTA2 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of GSTA2 protein]		 CTD PMID:19634143 NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798 		JBrowse link
G Gsta3 glutathione S-transferase alpha 3 multiple interactions
decreases expression
increases expression		 EXP Trientine inhibits the reaction [Streptozocin results in decreased expression of GSTA3 protein]; vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of GSTA3 mRNA] CTD PMID:16684804 PMID:19634143 NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240 		JBrowse link
G Gsta4 glutathione S-transferase alpha 4 increases expression EXP Streptozocin results in increased expression of GSTA4 protein CTD PMID:14693714 NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182 		JBrowse link
G Gsta5 glutathione S-transferase alpha 5 multiple interactions
increases expression		 EXP [resveratrol co-treated with Streptozocin] results in increased expression of GSTA5 mRNA
Streptozocin results in increased expression of GSTA5 mRNA		 CTD PMID:25905778 NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472 		JBrowse link
G Gstm2 glutathione S-transferase mu 2 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of GSTM2 mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of GSTM2 mRNA]		 CTD PMID:16684804 NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961 		JBrowse link
G Gstm5 glutathione S-transferase, mu 5 multiple interactions EXP [Streptozocin co-treated with Niacinamide] results in decreased expression of GSTM3 mRNA; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GSTM3 mRNA]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GSTM3 mRNA] CTD PMID:21439372 NCBI chr 2:195,531,599...195,534,562
Ensembl chr 2:195,531,495...195,534,553 		JBrowse link
G Gstm5l glutathione S-transferase, mu 5-like increases expression
multiple interactions		 EXP Streptozocin results in increased expression of GSTM5 mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of GSTM5 mRNA]		 CTD PMID:16684804 NCBI chr 2:195,544,424...195,549,895
Ensembl chr 2:195,544,426...195,628,961 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 decreases expression EXP Streptozocin results in decreased expression of GSTP1 mRNA CTD PMID:25905778 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Gucy1b2 guanylate cyclase 1 soluble subunit beta 2 decreases expression EXP Streptozocin results in decreased expression of GUCY1B2 mRNA CTD PMID:25905778 NCBI chr15:36,589,501...36,669,441
Ensembl chr15:36,598,883...36,669,441 		JBrowse link
G Gys1 glycogen synthase 1 decreases expression
multiple interactions
increases phosphorylation		 EXP Streptozocin results in decreased expression of GYS1 mRNA
Plant Extracts inhibits the reaction [Streptozocin results in decreased expression of GYS1 mRNA]; Tribulus extract inhibits the reaction [Streptozocin results in increased phosphorylation of GYS1 protein]		 CTD PMID:27038876 PMID:36627075 NCBI chr 1:95,915,443...95,935,292
Ensembl chr 1:95,915,443...95,935,292 		JBrowse link
G Gys2 glycogen synthase 2 multiple interactions EXP [Streptozocin co-treated with Niacinamide] affects the activity of GYS2 protein; resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] affects the activity of GYS2 protein] CTD PMID:19059388 NCBI chr 4:175,365,054...175,406,228
Ensembl chr 4:175,365,054...175,406,228 		JBrowse link
G H19 H19 imprinted maternally expressed transcript multiple interactions EXP [Resveratrol co-treated with Streptozocin] results in increased expression of H19 mRNA CTD PMID:25905778 NCBI chr 1:197,730,698...197,733,374
Ensembl chr 1:197,730,698...197,733,134 		JBrowse link
G H2bc3 H2B clustered histone 3 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of H2BC3 mRNA CTD PMID:33484791 NCBI chr17:41,380,056...41,380,686 JBrowse link
G Hamp hepcidin antimicrobial peptide multiple interactions EXP [Streptozocin co-treated with iron pentacarbonyl] results in increased expression of HAMP mRNA CTD PMID:22170771 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891 		JBrowse link
G Hao2 hydroxyacid oxidase 2 multiple interactions
decreases expression		 EXP [resveratrol co-treated with Streptozocin] results in decreased expression of HAO2 mRNA; Trientine inhibits the reaction [Streptozocin results in decreased expression of HAO2 protein]
Streptozocin results in decreased expression of HAO2 mRNA; Streptozocin results in decreased expression of HAO2 protein		 CTD PMID:19634143 PMID:25905778 NCBI chr 2:186,200,137...186,232,997
Ensembl chr 2:186,200,504...186,224,425 		JBrowse link
G Hapln1 hyaluronan and proteoglycan link protein 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of HAPLN1 mRNA CTD PMID:33484791 NCBI chr 2:20,631,640...20,696,388
Ensembl chr 2:20,631,640...20,693,777 		JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 decreases expression
multiple interactions
increases expression		 ISO
EXP		 Streptozocin results in decreased expression of HAVCR1 mRNA
[Streptozocin co-treated with Fructose] results in increased expression of HAVCR1 protein; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of HAVCR1 protein]; dapagliflozin promotes the reaction [Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of HAVCR1 protein]]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of HAVCR1 protein]; Metformin promotes the reaction [dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of HAVCR1 protein]]; sulbutiamine inhibits the reaction [Streptozocin results in increased expression of HAVCR1 protein]		 CTD PMID:19516248 PMID:30551545 PMID:37224990 NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698 		JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 multiple interactions
increases glycation		 EXP [Streptozocin co-treated with Niacinamide] results in increased glycosylation of HBA1 protein; coumarin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased glycosylation of HBA1 protein]
Streptozocin results in increased glycation of HBA1 protein		 CTD PMID:19647726 PMID:21139377 NCBI chr10:15,323,830...15,324,677
Ensembl chr10:15,307,815...15,338,392 		JBrowse link
G Hbb hemoglobin subunit beta decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of HBB-B1 protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of HBB-B1 protein]		 CTD PMID:19634143 NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012 		JBrowse link
G Hck HCK proto-oncogene, Src family tyrosine kinase multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of HCK mRNA CTD PMID:25905778 NCBI chr 3:141,571,587...141,614,696
Ensembl chr 3:141,571,587...141,614,693 		JBrowse link
G Hdac3 histone deacetylase 3 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of HDAC3 protein; HDAC3 protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of MIR10A mRNA]; HDAC3 protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CREB1 protein]; HDAC3 protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein] CTD PMID:27292126 NCBI chr18:29,770,637...29,789,850
Ensembl chr18:29,770,636...29,793,856 		JBrowse link
G Hdac5 histone deacetylase 5 multiple interactions EXP [Streptozocin co-treated with Fructose] results in increased expression of HDAC5 protein; Acetates inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of HDAC5 protein] CTD PMID:34656705 NCBI chr10:87,152,978...87,187,921
Ensembl chr10:87,152,978...87,188,235 		JBrowse link
G Hesx1 HESX homeobox 1 multiple interactions ISO [Diethylhexyl Phthalate co-treated with Streptozocin co-treated with Dietary Fats] results in decreased expression of HESX1 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of HESX1 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of HESX1 mRNA] CTD PMID:33484791 NCBI chr16:2,191,852...2,193,957
Ensembl chr16:2,191,852...2,193,957 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression
multiple interactions		 ISO
EXP		 Streptozocin results in increased expression of HIF1A protein
[Streptozocin co-treated with Dietary Fats] results in increased expression of HIF1A protein; bicalutamide promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of HIF1A protein]; Insulin promotes the reaction [Ozone inhibits the reaction [Streptozocin results in increased expression of HIF1A mRNA]]; Ozone inhibits the reaction [Streptozocin results in increased expression of HIF1A mRNA]		 CTD PMID:26073000 PMID:26614261 PMID:35151640 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hk1 hexokinase 1 decreases activity
multiple interactions		 EXP Streptozocin results in decreased activity of HK1 protein
[homocastasterone analog co-treated with Streptozocin] results in increased expression of HK1 mRNA; plumbagin inhibits the reaction [Streptozocin results in decreased activity of HK1 protein]		 CTD PMID:22960630 PMID:28822685 NCBI chr20:30,230,488...30,332,099
Ensembl chr20:30,230,486...30,332,131 		JBrowse link
G Hmgb1 high mobility group box 1 increases expression
multiple interactions		 ISO Streptozocin results in increased expression of HMGB1 mRNA
manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Streptozocin results in increased expression of HMGB1 mRNA]		 CTD PMID:19833897 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions
increases expression		 EXP
ISO		 [Dietary Fats co-treated with Streptozocin] results in increased expression of HMGCR mRNA; [Streptozocin co-treated with Cadmium] results in increased activity of HMGCR protein; [Streptozocin co-treated with Niacinamide] results in increased activity of HMGCR protein; [tetrahydrocurcumin co-treated with Chlorogenic Acid] results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in increased activity of HMGCR protein]; Chlorogenic Acid results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in increased activity of HMGCR protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased activity of HMGCR protein]; tetrahydrocurcumin results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in increased activity of HMGCR protein]; Warfarin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of HMGCR mRNA]
Streptozocin results in increased expression of HMGCR mRNA
Acrylamide inhibits the reaction [Streptozocin results in increased expression of HMGCR mRNA]		 CTD PMID:20696151 PMID:25240712 PMID:25905778 PMID:27488359 PMID:34896238 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of HMGCS2 mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of HMGCS2 mRNA]		 CTD PMID:16684804 NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130 		JBrowse link
G Hmox1 heme oxygenase 1 decreases activity
multiple interactions
increases expression
decreases expression		 EXP
ISO		 Streptozocin results in decreased activity of HMOX1 protein
[cobaltiprotoporphyrin co-treated with Streptozocin] results in increased activity of HMOX1 protein; [cobaltiprotoporphyrin co-treated with Streptozocin] results in increased expression of HMOX1 protein; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of HMOX1 mRNA; [Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of HMOX1 protein]; [Streptozocin co-treated with Dietary Fats] results in decreased expression of HMOX1 protein; [Streptozocin co-treated with Hemin] results in increased activity of HMOX1 protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of HMOX1 protein; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of HMOX1 mRNA]; caffeic acid phenethyl ester inhibits the reaction [Streptozocin results in increased expression of HMOX1 protein]; chromium mesoporphyrin inhibits the reaction [[Streptozocin co-treated with Hemin] results in increased activity of HMOX1 protein]; cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of and results in decreased activity of HMOX1 protein]; cobaltiprotoporphyrin promotes the reaction [Streptozocin results in increased expression of HMOX1 protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein]; diallyl trisulfide inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein]; Dimethyl Fumarate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of HMOX1 protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of HMOX1 mRNA]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of HMOX1 protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of HMOX1 mRNA]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of HMOX1 protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of HMOX1 mRNA]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of HMOX1 mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of HMOX1 protein]; Metformin inhibits the reaction [Streptozocin results in decreased expression of HMOX1 mRNA]; Metformin inhibits the reaction [Streptozocin results in increased expression of HMOX1 mRNA]; palbinone inhibits the reaction [Streptozocin results in decreased expression of HMOX1 mRNA]; Propofol inhibits the reaction [Streptozocin results in decreased activity of HMOX1 protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of HMOX1 protein]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of HMOX1 mRNA]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein]; Streptozocin results in decreased expression of and results in decreased activity of HMOX1 protein; Streptozocin results in increased expression of and results in decreased activity of HMOX1 protein; STUB1 inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of HMOX1 mRNA]; tin mesoporphyrin inhibits the reaction [[cobaltiprotoporphyrin co-treated with Streptozocin] results in increased activity of HMOX1 protein]; tin mesoporphyrin inhibits the reaction [[cobaltiprotoporphyrin co-treated with Streptozocin] results in increased expression of HMOX1 protein]
Streptozocin results in increased expression of HMOX1 mRNA; Streptozocin results in increased expression of HMOX1 protein
HMOX1 protein inhibits the reaction [Streptozocin results in decreased expression of SLC25A19 protein]
[Dietary Fats co-treated with Streptozocin] results in decreased expression of HMOX1 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of HMOX1 mRNA; [Streptozocin co-treated with sulforaphane] results in increased expression of HMOX1; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of HMOX1 mRNA]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of HMOX1 mRNA]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of HMOX1 mRNA]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein]
Streptozocin results in decreased expression of HMOX1 mRNA; Streptozocin results in decreased expression of HMOX1 protein		 CTD PMID:16309587 PMID:16595661 PMID:19019021 PMID:19190261 PMID:21439372 More... NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hmox2 heme oxygenase 2 multiple interactions
increases response to substance		 ISO cobaltiprotoporphyrin inhibits the reaction [HMOX2 gene mutant form results in increased susceptibility to Streptozocin]; tin mesoporphyrin promotes the reaction [HMOX2 gene mutant form results in increased susceptibility to Streptozocin] CTD PMID:16524951 NCBI chr10:10,797,076...10,831,178
Ensembl chr10:10,797,055...10,831,148 		JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha increases expression
multiple interactions		 ISO Streptozocin results in increased expression of HNF4A mRNA
Acrylamide inhibits the reaction [Streptozocin results in increased expression of HNF4A mRNA]		 CTD PMID:34896238 NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320 		JBrowse link
G Hopx HOP homeobox multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of HOPX mRNA CTD PMID:25905778 NCBI chr14:31,055,912...31,082,909
Ensembl chr14:31,075,148...31,082,909 		JBrowse link
G Hp haptoglobin multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of HP mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of HP mRNA] CTD PMID:33484791 NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523 		JBrowse link
G Hras HRas proto-oncogene, GTPase decreases farnesylation EXP Streptozocin results in decreased farnesylation of HRAS protein CTD PMID:19002579 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615 		JBrowse link
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of HSD17B10 protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of HSD17B10 protein]		 CTD PMID:21136691 NCBI chr  X:21,089,142...21,091,603
Ensembl chr  X:21,089,122...21,109,488 		JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of HSD17B2 mRNA CTD PMID:25905778 NCBI chr19:45,753,576...45,825,203
Ensembl chr19:45,753,574...45,825,202 		JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 affects expression ISO Streptozocin affects the expression of HSD17B4 mRNA CTD PMID:18583417 NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952 		JBrowse link
G Hsd3b3 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 affects expression ISO Streptozocin affects the expression of HSD3B3 mRNA CTD PMID:18583417 NCBI chr 2:186,138,044...186,144,024
Ensembl chr 2:186,138,044...186,144,033 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases expression EXP Streptozocin results in increased expression of HSP90AA1 mRNA CTD PMID:37081038 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268 		JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 multiple interactions
increases expression 		ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of HSP90B1 mRNA
streptozocin increases expression of Hsp90b1 protein in heart		 CTD
RGD		 PMID:26522834 PMID:36044268 RGD:156430337 NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788 		JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 affects expression ISO Streptozocin affects the expression of HSPA2 mRNA CTD PMID:18583417 NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions
decreases expression
increases expression
increases expression 		EXP
ISO		 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of HSPA5 protein]; [Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of HSPA5 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of HSPA5 mRNA; Bilirubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of HSPA5 mRNA]; Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of HSPA5 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of HSPA5 protein]; moutan cortex inhibits the reaction [Streptozocin results in increased expression of and results in increased secretion of HSPA5 protein]; Streptozocin results in increased expression of and results in increased secretion of HSPA5 protein; Trientine inhibits the reaction [Streptozocin results in decreased expression of HSPA5 protein]; Vitamin B 12 inhibits the reaction [Streptozocin results in increased expression of HSPA5 protein]
[Dietary Fats co-treated with Streptozocin] results in increased expression of HSPA5 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of HSPA5 protein; [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of HSPA5 mRNA]; [Streptozocin co-treated with Dietary Fats] results in increased expression of HSPA5 protein; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of HSPA5 mRNA; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of HSPA5 mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of HSPA5 protein]; sulforaphane inhibits the reaction [Streptozocin results in increased expression of HSPA5 protein]
streptozocin increases expression of Hspa5 protein in heart		 CTD
RGD		 PMID:19634143 PMID:24967692 PMID:26522834 PMID:27664441 PMID:30980806 More... RGD:156430337 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 decreases expression
multiple interactions		 EXP Streptozocin results in decreased expression of HSPA9 protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of HSPA9 protein]		 CTD PMID:19634143 NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 multiple interactions
increases phosphorylation		 EXP baicalin inhibits the reaction [Streptozocin results in increased phosphorylation of HSPB1 protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of HSPB1 protein] CTD PMID:18204486 PMID:34414639 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 multiple interactions
increases expression
decreases expression		 EXP Trientine inhibits the reaction [Streptozocin results in decreased expression of HSPD1 protein]; Trientine inhibits the reaction [Streptozocin results in increased expression of HSPD1 protein] CTD PMID:19634143 PMID:21136691 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662 		JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 multiple interactions
decreases expression		 EXP Trientine inhibits the reaction [Streptozocin results in decreased expression of HSPE1 protein] CTD PMID:19634143 NCBI chr 9:56,589,912...56,593,000
Ensembl chr 9:56,589,789...56,593,089 		JBrowse link
G Hspg2 heparan sulfate proteoglycan 2 increases expression
multiple interactions		 EXP Streptozocin results in increased expression of HSPG2 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of HSPG2 protein]		 CTD PMID:19634143 NCBI chr 5:149,677,437...149,778,594
Ensembl chr 5:149,677,476...149,778,594 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A multiple interactions EXP Streptozocin inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased activity of HTR1A protein] CTD PMID:18622176 NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A multiple interactions EXP Streptozocin inhibits the reaction [4-iodo-2,5-dimethoxyphenylisopropylamine results in increased activity of HTR2A protein] CTD PMID:18622176 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of HTR2C mRNA CTD PMID:33484791 NCBI chr  X:110,640,777...110,870,288
Ensembl chr  X:110,641,153...110,870,287 		JBrowse link
G Iapp islet amyloid polypeptide multiple interactions
decreases expression		 EXP
ISO		 rosiglitazone inhibits the reaction [Streptozocin results in decreased expression of IAPP mRNA]
[octylphenol co-treated with Streptozocin] results in decreased expression of IAPP mRNA; Streptozocin inhibits the reaction [Ethinyl Estradiol results in decreased expression of IAPP mRNA]		 CTD PMID:18998217 PMID:29935216 NCBI chr 4:175,237,107...175,244,373
Ensembl chr 4:175,237,115...175,242,920 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
increases expression		 ISO
EXP		 AM6545 inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; AM6545 inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]]; Clodronic Acid inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; Curcumin analog inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; dehydroxymethylepoxyquinomicin inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; dehydroxymethylepoxyquinomicin inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; Perindopril inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; Perindopril inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; sulforaphane inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; Telmisartan inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]
Streptozocin results in increased expression of ICAM1 mRNA; Streptozocin results in increased expression of ICAM1 protein
[Streptozocin co-treated with Cholesterol, Dietary] results in increased expression of ICAM1 protein; Atorvastatin inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; Atorvastatin inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; candesartan inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; cloricromen inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; fasudil inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Cholesterol, Dietary] results in increased expression of ICAM1 protein]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; moutan cortex inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; Rosiglitazone inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; Rosiglitazone inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]		 CTD PMID:10485912 PMID:14871415 PMID:15892581 PMID:16129698 PMID:16139267 More... NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Id2 inhibitor of DNA binding 2 decreases expression EXP Streptozocin results in decreased expression of ID2 mRNA CTD PMID:25905778 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400 		JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 affects expression ISO Streptozocin affects the expression of IDH2 mRNA CTD PMID:18583417 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025 		JBrowse link
G Ifitm3 interferon induced transmembrane protein 3 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of IFITM3 mRNA CTD PMID:25905778 NCBI chr 1:196,111,026...196,112,135
Ensembl chr 1:196,111,043...196,112,203 		JBrowse link
G Ifng interferon gamma multiple interactions
increases expression
decreases expression		 ISO
EXP		 Clodronic Acid inhibits the reaction [Streptozocin results in increased expression of IFNG protein]; Dronabinol inhibits the reaction [Streptozocin results in increased expression of IFNG mRNA]; S-Nitroso-N-Acetylpenicillamine inhibits the reaction [Streptozocin results in increased expression of IFNG protein]; Sodium Selenite inhibits the reaction [Streptozocin results in increased expression of IFNG mRNA]
Streptozocin results in increased expression of IFNG mRNA; Streptozocin results in increased expression of IFNG protein
arjunolic acid inhibits the reaction [Streptozocin results in decreased expression of IFNG protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of IFNG protein]		 CTD PMID:11357882 PMID:15862027 PMID:15892581 PMID:15975818 PMID:18789669 More... NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Igdcc4 immunoglobulin superfamily, DCC subclass, member 4 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of IGDCC4 mRNA CTD PMID:33484791 NCBI chr 8:65,621,893...65,657,651
Ensembl chr 8:65,621,897...65,657,648 		JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions
decreases expression
increases expression		 ISO
EXP		 [Dietary Fats co-treated with Streptozocin] results in increased expression of IGF1 mRNA; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IGF1 mRNA]; IGF1 protein inhibits the reaction [Streptozocin results in increased expression of AGT protein]; IGF1 protein inhibits the reaction [Streptozocin results in increased expression of BAX protein]; IGF1 protein inhibits the reaction [Streptozocin results in increased expression of TRP53 protein]; Metformin inhibits the reaction [Streptozocin results in decreased expression of IGF1 protein]; puerarin inhibits the reaction [Streptozocin results in decreased expression of IGF1 protein]
Streptozocin results in decreased expression of IGF1 mRNA; Streptozocin results in decreased expression of IGF1 protein
Streptozocin results in increased expression of IGF1 protein
[Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IGF1 protein]; [Streptozocin co-treated with Dietary Fats] results in increased expression of IGF1 protein; Dimethyl Fumarate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IGF1 protein]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IGF1 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IGF1 protein]; Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of IGF1 protein]; Rivastigmine inhibits the reaction [Streptozocin results in decreased expression of IGF1 protein]; Wortmannin inhibits the reaction [Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of IGF1 protein]]		 CTD PMID:7637645 PMID:9868179 PMID:11375343 PMID:23927877 PMID:25617479 More... NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor decreases expression
multiple interactions		 EXP
ISO		 Streptozocin results in decreased expression of IGF1R protein
[Dietary Fats co-treated with Streptozocin co-treated with Ovalbumin] results in decreased expression of IGF1R mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Ovalbumin] results in decreased expression of IGF1R protein; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin co-treated with Ovalbumin] results in decreased expression of IGF1R mRNA]; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin co-treated with Ovalbumin] results in decreased expression of IGF1R protein]; xanthoceraside inhibits the reaction [Streptozocin results in decreased expression of IGF1R protein]
[Streptozocin co-treated with CNR1 protein] affects the expression of IGF1R protein		 CTD PMID:23562514 PMID:30721768 PMID:36547818 NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777 		JBrowse link
G Igf2bp3 insulin-like growth factor 2 mRNA binding protein 3 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of IGF2BP3 mRNA CTD PMID:25905778 NCBI chr 4:78,060,494...78,195,007
Ensembl chr 4:78,060,494...78,194,865 		JBrowse link
G Igf2r insulin-like growth factor 2 receptor increases expression
multiple interactions
increases response to substance		 EXP Streptozocin results in increased expression of IGF2R protein
[IGF2R protein alternative form results in increased susceptibility to Streptozocin] which results in increased abundance of Cholesterol; [IGF2R protein alternative form results in increased susceptibility to Streptozocin] which results in increased abundance of Triglycerides; [Streptozocin co-treated with IGF2R protein modified form] results in increased expression of CASP3 protein modified form; IGF2R protein modified form inhibits the reaction [Streptozocin results in increased expression of CASP9 protein]; IGF2R protein modified form promotes the reaction [Streptozocin results in decreased expression of BCL2 protein]; IGF2R protein modified form promotes the reaction [Streptozocin results in decreased expression of NFKBIA protein modified form]; IGF2R protein modified form promotes the reaction [Streptozocin results in increased expression of IL1B protein]; IGF2R protein modified form promotes the reaction [Streptozocin results in increased expression of PTGS2 protein]; IGF2R protein modified form promotes the reaction [Streptozocin results in increased expression of RELA protein modified form]; IGF2R protein modified form promotes the reaction [Streptozocin results in increased expression of TNF protein]; Streptozocin promotes the reaction [IGF2R protein alternative form results in increased abundance of Triglycerides]; Streptozocin promotes the reaction [IGF2R protein modified form results in decreased expression of BCL2 protein modified form]; Streptozocin promotes the reaction [IGF2R protein modified form results in decreased expression of NFKBIA protein modified form]; Streptozocin promotes the reaction [IGF2R protein modified form results in increased expression of IL6 protein]; Streptozocin promotes the reaction [IGF2R protein modified form results in increased expression of RELA protein modified form]		 CTD PMID:35993117 PMID:36462176 NCBI chr 1:47,979,109...48,067,501
Ensembl chr 1:47,979,109...48,067,501 		JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of IGFBP2 mRNA CTD PMID:25905778 NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937 		JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 multiple interactions
increases expression		 ISO 2-amino-6-boronohexanoic acid inhibits the reaction [Streptozocin results in increased expression of IGFBP3 mRNA] CTD PMID:29673160 NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083 		JBrowse link
G Igfbp7 insulin-like growth factor binding protein 7 increases expression ISO Streptozocin results in increased expression of IGFBP7 mRNA CTD