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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:stanozolol
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Accession:CHEBI:9249 term browser browse the term
Definition:An organic heteropentacyclic compound resulting from the formal condensation of the 3-keto-aldehyde moiety of oxymetholone with hydrazine. Like oxymetholone, it is a synthetic anabolic steroid. It has both anabolic and androgenic properties, and has been used to treat hereditary angioedema and various vascular disorders. It has also been widely abused by professional athletes.
Synonyms:exact_synonym: (1S,3aS,3bR,5aS,10aS,10bS,12aS)-1,10a,12a-trimethyl-1,2,3,3a,3b,4,5,5a,6,7,10,10a,10b,11,12,12a-hexadecahydrocyclopenta[5,6]naphtho[1,2-f]indazol-1-ol
 related_synonym: Androstanazole;   Formula=C21H32N2O;   InChI=1S/C21H32N2O/c1-19-11-13-12-22-23-18(13)10-14(19)4-5-15-16(19)6-8-20(2)17(15)7-9-21(20,3)24/h12,14-17,24H,4-11H2,1-3H3,(H,22,23)/t14-,15+,16-,17-,19-,20-,21-/m0/s1;   InChIKey=LKAJKIOFIWVMDJ-IYRCEVNGSA-N;   SMILES=C[C@]1(O)CC[C@H]2[C@@H]3CC[C@H]4Cc5[nH]ncc5C[C@]4(C)[C@H]3CC[C@]12C;   Stromba;   Strombaject;   Winstrol;   estanozolol;   stanozololum
 xref: CAS:10418-03-8;   DrugBank:DB06718;   Drug_Central:2477;   HMDB:HMDB0003116;   KEGG:C07311;   KEGG:D00444
 xref_mesh: MESH:D013197
 xref: PMID:20020362;   PMID:20209649;   PMID:20480277;   PMID:21496393;   PMID:21769864;   PMID:22197661;   PMID:22729959;   PMID:23374366;   PMID:23873860;   PMID:23978309;   PMID:24021270;   PMID:24405322;   Patent:US3030358;   Reaxys:8359772;   Wikipedia:Stanozolol



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stanozolol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions
increases activity
ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; 4-cumylphenol inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; 4-tert-octylphenol inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; bisphenol A inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; butylbenzyl phthalate inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Chlordecone inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Corticosterone inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Coumestrol inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Diethylstilbestrol inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Estradiol inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Ethinyl Estradiol inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; ethyl-p-hydroxybenzoate inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Flutamide inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Flutamide metabolite inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Genistein inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Hexestrol inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; hydroxyflutamide inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; kaempferol inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Ketoconazole inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Linuron inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Methoxychlor inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Methoxychlor inhibits the reaction [Stanozolol results in increased activity of AR protein]; Methoxychlor metabolite inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Reserpine inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Spironolactone inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Stanozolol binds to and results in increased activity of AR protein; Testosterone inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; vinclozolin inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; vinclozolin inhibits the reaction [Stanozolol results in increased activity of AR protein] CTD PMID:28009930 PMID:28377212 PMID:29162470 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Gpx1 glutathione peroxidase 1 decreases activity EXP Stanozolol results in decreased activity of GPX1 protein CTD PMID:36029803 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Mir125b2 microRNA 125b-2 increases expression EXP Stanozolol results in increased expression of MIR125B2 CTD PMID:36029803 NCBI chr11:16,245,620...16,245,707 JBrowse link
G Mir146a microRNA 146a increases expression EXP Stanozolol results in increased expression of MIR146A CTD PMID:36029803 NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610
JBrowse link
G Tert telomerase reverse transcriptase increases activity EXP Stanozolol results in increased activity of TERT protein CTD PMID:29717770 NCBI chr 1:29,637,213...29,659,561
Ensembl chr 1:29,637,506...29,659,561
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19898
    role 19868
      application 19714
        anti-anaemic agent 107
          oxymetholone 13
            stanozolol 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19898
    subatomic particle 19896
      composite particle 19896
        hadron 19896
          baryon 19896
            nucleon 19896
              atomic nucleus 19896
                atom 19896
                  main group element atom 19835
                    p-block element atom 19835
                      carbon group element atom 19774
                        carbon atom 19771
                          organic molecular entity 19771
                            heteroorganic entity 19528
                              organochalcogen compound 19290
                                organooxygen compound 19206
                                  carbonyl compound 18929
                                    ketone 17272
                                      oxo steroid 10542
                                        3-oxo steroid 9929
                                          3-oxo-5alpha-steroid 1006
                                            oxymetholone 13
                                              stanozolol 5
paths to the root