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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:eliprodil
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Accession:CHEBI:91784 term browser browse the term
Definition:A racemate comprising equimolar amounts of (R)- and (S)-eliprodil. It is a non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist and an anti-ischaemic agent that exhibits neuroprotective properties.
Synonyms:exact_synonym: rac-1-(4-chlorophenyl)-2-[4-(4-fluorobenzyl)piperidin-1-yl]ethanol
 related_synonym: (+-)-alpha-(p-chlorophenyl)-4-(p-fluorobenzyl)-1-piperidineethanol;   (RS)-eliprodil;   Formula=C20H23ClFNO;   SL-82,0715;   SL-820715;   SL820715;   eliprodilum;   rac-1-(4-chlorophenyl)-2-{4-[(4-fluorophenyl)methyl]piperidin-1-yl}ethan-1-ol;   racemic eliprodil
 xref: CAS:119431-25-3;   Chemspider:54708;   DrugBank:DB12869;   HMDB:HMDB0251748;   LINCS:LSM-1677
 xref_mesh: MESH:C058083
 xref: PMID:10235550;   PMID:10235551;   PMID:10890168;   PMID:1354073;   PMID:15064913;   PMID:15302678;   PMID:24134630;   PMID:2849668;   PMID:29191857;   PMID:7814824;   PMID:8088348;   PMID:8402196;   PMID:8545484;   PMID:8719234;   PMID:8901012;   PMID:9089691;   PMID:9128850;   PMID:9369990;   PMID:9439799;   PMID:9519265;   PMID:9674557;   PMID:9718264;   PMID:9874159;   PMID:9932955;   Patent:EP0718407;   Wikipedia:Eliprodil


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eliprodil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions ISO eliprodil inhibits the reaction [KCNH2 protein results in increased transport of Thallium] CTD PMID:19583963 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19880
    chemical entity 19878
      chemical substance 14399
        mixture 13717
          racemate 12094
            eliprodil 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19880
    subatomic particle 19878
      composite particle 19878
        hadron 19878
          baryon 19878
            nucleon 19878
              atomic nucleus 19878
                atom 19878
                  main group element atom 19817
                    main group molecular entity 19817
                      s-block molecular entity 19653
                        hydrogen molecular entity 19634
                          hydrides 19144
                            inorganic hydride 18161
                              pnictogen hydride 18151
                                nitrogen hydride 18064
                                  azane 17872
                                    ammonia 17871
                                      organic amino compound 17871
                                        tertiary amino compound 10153
                                          1-(4-chlorophenyl)-2-[4-(4-fluorobenzyl)piperidin-1-yl]ethanol 1
                                            (R)-eliprodil 1
                                              eliprodil 1
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