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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:scullcapflavone II
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Accession:CHEBI:9061 term browser browse the term
Definition:A tetramethoxyflavone that is flavone substituted by methoxy groups at positions 6, 7, 8 and 6' and hydroxy groups at positons 5 and 2' respectively.
Synonyms:exact_synonym: 5-hydroxy-2-(2-hydroxy-6-methoxyphenyl)-6,7,8-trimethoxy-4H-1-benzopyran-4-one
 related_synonym: 5,2'-dihydroxy-6,7,8,6'-tetramethoxyflavone;   5-hydroxy-2-(2-hydroxy-6-methoxy-phenyl)-6,7,8-trimethoxy-chromen-4-one;   Formula=C19H18O8;   InChI=1S/C19H18O8/c1-23-11-7-5-6-9(20)13(11)12-8-10(21)14-15(22)17(24-2)19(26-4)18(25-3)16(14)27-12/h5-8,20,22H,1-4H3;   InChIKey=GMQFOKBGMKVUQZ-UHFFFAOYSA-N;   SMILES=COc1cccc(O)c1-c1cc(=O)c2c(O)c(OC)c(OC)c(OC)c2o1;   neobaicalein;   skullcapflavone II
 xref: CAS:55084-08-7;   KEGG:C10183;   KNApSAcK:C00001099;   LIPID_MAPS_instance:LMPK12111423
 xref_mesh: MESH:C047405
 xref: PMID:22314230;   PMID:25546119;   PMID:28886581;   PMID:31167359;   PMID:35398391;   PMID:36605189;   PMID:36697978;   PMID:36825003;   PMID:36865041;   PMID:37120983;   Reaxys:3634558


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scullcapflavone II term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 affects binding ISO skullcapflavone II binds to CASP3 protein CTD PMID:32913905 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 affects binding ISO skullcapflavone II binds to MAPK14 protein CTD PMID:32913905 NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20862
    role 20820
      application 20621
        anti-asthmatic agent 9361
          anti-asthmatic drug 8705
            scullcapflavone II 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 20862
    subatomic particle 20860
      composite particle 20860
        hadron 20860
          baryon 20860
            nucleon 20860
              atomic nucleus 20860
                atom 20860
                  main group element atom 20781
                    p-block element atom 20781
                      carbon group element atom 20715
                        carbon atom 20710
                          organic molecular entity 20710
                            organic molecule 20654
                              organic cyclic compound 20404
                                organic heterocyclic compound 19388
                                  oxacycle 18300
                                    benzopyran 12186
                                      1-benzopyran 11917
                                        flavonoid 7550
                                          anthoxanthin 4621
                                            flavones 4621
                                              hydroxyflavone 4598
                                                dihydroxyflavone 562
                                                  scullcapflavone II 2
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