The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
A member of the class of coumarins that is esculetin in which the two hydroxy groups at positions 6 and 7 are replaced by methoxy groups. It is a major constituent of the Chinese herbal medicine Yin Chen Hao, and exhibits a variety of pharmacological activities such as anti-inflammatory, anti-allergic, and anti-tumor activities.
scoparone affects the reaction [[Dietary Fats co-treated with Dietary Sugars co-treated with Diethylnitrosamine] results in increased phosphorylation of AKT1 protein]
scoparone inhibits the reaction [[Dietary Fats co-treated with Dietary Sugars co-treated with Diethylnitrosamine] results in decreased expression of ALB protein]
scoparone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]; scoparone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of CCL2 protein] scoparone inhibits the reaction [Diethylnitrosamine promotes the reaction [[Dietary Fats co-treated with Dietary Sugars] results in increased expression of CCL2 mRNA]]; scoparone inhibits the reaction [Diethylnitrosamine promotes the reaction [[Dietary Fats co-treated with Dietary Sugars] results in increased expression of CCL2 protein]]
[Dietary Sugars co-treated with Dietary Fats co-treated with scoparone] results in increased expression of GPT protein; scoparone inhibits the reaction [Diethylnitrosamine promotes the reaction [[Dietary Sugars co-treated with Dietary Fats] results in increased expression of GPT protein]]
scoparone inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactose] results in increased expression of IFNB1 protein]
scoparone affects the reaction [[Dietary Fats co-treated with Dietary Sugars co-treated with Diethylnitrosamine] results in increased metabolism of IL1B protein]
scoparone inhibits the reaction [[Galactose co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of IL6 protein]
scoparone inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactose] results in increased phosphorylation of IRF3 protein]
scoparone inhibits the reaction [[Galactose co-treated with lipopolysaccharide, Escherichia coli O111 B4] affects the localization of and results in increased expression of JUN protein modified form]
scoparone affects the reaction [[Dietary Fats co-treated with Dietary Sugars co-treated with Diethylnitrosamine] results in increased phosphorylation of MAPK14 protein]
scoparone results in decreased expression of MMP9 mRNA scoparone affects the reaction [[Dietary Fats co-treated with Dietary Sugars co-treated with Diethylnitrosamine] results in increased expression of MMP9 protein]; scoparone inhibits the reaction [Diethylnitrosamine promotes the reaction [[Dietary Fats co-treated with Dietary Sugars] results in increased expression of MMP9 mRNA]]
scoparone inhibits the reaction [[Galactose co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of MYD88 protein]
scoparone inhibits the reaction [Diethylnitrosamine promotes the reaction [[Dietary Fats co-treated with Dietary Sugars] results in increased expression of NOS2 mRNA]]
scoparone inhibits the reaction [Diethylnitrosamine promotes the reaction [[Dietary Fats co-treated with Dietary Sugars] results in increased expression of PTGS2 mRNA]]
scoparone affects the reaction [[Dietary Fats co-treated with Dietary Sugars co-treated with Diethylnitrosamine] results in increased phosphorylation of RELA protein]; scoparone inhibits the reaction [[Galactose co-treated with lipopolysaccharide, Escherichia coli O111 B4] affects the localization of and results in increased expression of RELA protein]; scoparone inhibits the reaction [Diethylnitrosamine promotes the reaction [[Dietary Fats co-treated with Dietary Sugars] results in increased expression of RELA mRNA]]; scoparone inhibits the reaction [Diethylnitrosamine promotes the reaction [[Dietary Fats co-treated with Dietary Sugars] results in increased expression of RELA protein]] scoparone inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of RELA protein]; scoparone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein]
scoparone inhibits the reaction [[Galactose co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of TICAM1 protein]
scoparone inhibits the reaction [[Galactose co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of TLR4 protein]
scoparone inhibits the reaction [[Galactose co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of TNF protein]; scoparone inhibits the reaction [Diethylnitrosamine promotes the reaction [[Dietary Fats co-treated with Dietary Sugars] results in increased expression of TNF mRNA]]; scoparone inhibits the reaction [Diethylnitrosamine promotes the reaction [[Dietary Fats co-treated with Dietary Sugars] results in increased expression of TNF protein]]
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [scoparone results in increased expression of TYR protein]; scoparone results in increased expression of and results in increased activity of TYR protein scoparone results in increased expression of TYR mRNA
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