|
G |
Abcb11 |
ATP binding cassette subfamily B member 11 |
multiple interactions |
ISO |
[furan co-treated with rhodioloside] results in increased expression of ABCB11 mRNA |
CTD |
PMID:32251705 |
|
NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
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G |
Abcb1a |
ATP binding cassette subfamily B member 1A |
multiple interactions |
ISO |
rhodioloside affects the reaction [ABCB1 protein results in increased transport of Digoxin] |
CTD |
PMID:24380838 |
|
NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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G |
Ache |
acetylcholinesterase |
multiple interactions |
EXP |
rhodioloside inhibits the reaction [Isoflurane results in increased activity of ACHE protein] |
CTD |
PMID:28084090 |
|
NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
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G |
Akt1 |
AKT serine/threonine kinase 1 |
multiple interactions |
EXP |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [rhodioloside inhibits the reaction [Colistin results in decreased phosphorylation of AKT1 protein]]; rhodioloside inhibits the reaction [Colistin results in decreased phosphorylation of AKT1 protein] |
CTD |
PMID:28465020 |
|
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
Alpl |
alkaline phosphatase, biomineralization associated |
increases activity increases expression |
ISO |
rhodioloside results in increased activity of ALPL protein rhodioloside results in increased expression of ALPL mRNA |
CTD |
PMID:24055767 |
|
NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
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G |
Aoc1 |
amine oxidase, copper containing 1 |
decreases secretion |
ISO |
rhodioloside results in decreased secretion of AOC1 protein |
CTD |
PMID:37530723 |
|
NCBI chr 4:77,812,260...77,831,846
Ensembl chr 4:77,812,260...77,831,840
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G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions |
ISO EXP |
rhodioloside inhibits the reaction [Doxorubicin results in increased expression of BAX mRNA] rhodioloside inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of BAX protein]; sirtinol inhibits the reaction [rhodioloside inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of BAX protein]] 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [rhodioloside inhibits the reaction [Colistin results in increased expression of BAX protein]]; rhodioloside inhibits the reaction [cobaltous chloride results in increased expression of BAX protein]; rhodioloside inhibits the reaction [Colistin results in increased expression of BAX protein]; rhodioloside inhibits the reaction [Doxorubicin results in increased expression of BAX mRNA]; rhodioloside inhibits the reaction [Doxorubicin results in increased expression of BAX protein] |
CTD |
PMID:21499890 PMID:24072175 PMID:28465020 PMID:28851138 |
|
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bcl2 |
BCL2, apoptosis regulator |
increases expression multiple interactions |
ISO EXP |
rhodioloside results in increased expression of BCL2 mRNA rhodioloside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of BCL2 protein]; sirtinol inhibits the reaction [rhodioloside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of BCL2 protein]] 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [rhodioloside inhibits the reaction [Colistin results in decreased expression of BCL2 protein]]; rhodioloside inhibits the reaction [Colistin results in decreased expression of BCL2 protein]; rhodioloside inhibits the reaction [Doxorubicin results in decreased expression of BCL2 mRNA] rhodioloside results in increased expression of BCL2 protein |
CTD |
PMID:24072175 PMID:28465020 PMID:28851138 |
|
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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|
G |
Bmp2 |
bone morphogenetic protein 2 |
increases expression |
ISO |
rhodioloside results in increased expression of BMP2 mRNA |
CTD |
PMID:24055767 |
|
NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
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G |
Bmp6 |
bone morphogenetic protein 6 |
increases expression |
ISO |
rhodioloside results in increased expression of BMP6 mRNA |
CTD |
PMID:24055767 |
|
NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365
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G |
Bmp7 |
bone morphogenetic protein 7 |
increases expression |
ISO |
rhodioloside results in increased expression of BMP7 mRNA |
CTD |
PMID:24055767 |
|
NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788
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G |
Casp1 |
caspase 1 |
multiple interactions |
EXP ISO |
rhodioloside inhibits the reaction [Glucose results in increased expression of CASP1 protein] rhodioloside inhibits the reaction [furan results in increased cleavage of CASP1 protein] |
CTD |
PMID:29031534 PMID:34450210 |
|
NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
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G |
Casp12 |
caspase 12 |
multiple interactions |
ISO |
rhodioloside inhibits the reaction [furan results in increased cleavage of CASP12 protein] |
CTD |
PMID:34450210 |
|
NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
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|
G |
Casp3 |
caspase 3 |
multiple interactions |
EXP ISO |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [rhodioloside inhibits the reaction [Colistin results in increased activity of and results in increased cleavage of CASP3 protein]]; rhodioloside inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased cleavage of CASP3 protein]; rhodioloside inhibits the reaction [Colistin results in increased activity of and results in increased cleavage of CASP3 protein]; rhodioloside inhibits the reaction [Doxorubicin results in increased cleavage of CASP3 protein] rhodioloside inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased activity of CASP3 protein]; sirtinol inhibits the reaction [rhodioloside inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased activity of CASP3 protein]] |
CTD |
PMID:24072175 PMID:28465020 PMID:28851138 PMID:30991096 |
|
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Cat |
catalase |
increases expression multiple interactions |
ISO EXP |
rhodioloside results in increased expression of CAT mRNA; rhodioloside results in increased expression of CAT protein rhodioloside inhibits the reaction [furan results in decreased activity of CAT protein]; rhodioloside inhibits the reaction [furan results in decreased expression of CAT mRNA]; rhodioloside inhibits the reaction [Streptozocin results in decreased activity of CAT protein] |
CTD |
PMID:24072175 PMID:31682803 PMID:34450210 |
|
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Cdh2 |
cadherin 2 |
multiple interactions |
ISO |
rhodioloside inhibits the reaction [Streptozocin results in decreased expression of CDH2 protein] |
CTD |
PMID:31682803 |
|
NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
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G |
Cert1 |
ceramide transporter 1 |
multiple interactions |
EXP |
rhodioloside inhibits the reaction [Glucose results in increased expression of CERT1 mRNA] |
CTD |
PMID:29031534 |
|
NCBI chr 2:27,882,546...27,987,090
Ensembl chr 2:27,882,555...27,987,074
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G |
Chat |
choline O-acetyltransferase |
multiple interactions |
EXP |
rhodioloside inhibits the reaction [Isoflurane results in decreased activity of CHAT protein] |
CTD |
PMID:28084090 |
|
NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093
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G |
Cldn11 |
claudin 11 |
multiple interactions |
ISO |
rhodioloside inhibits the reaction [Streptozocin results in decreased expression of CLDN11 protein] |
CTD |
PMID:31682803 |
|
NCBI chr 2:112,207,745...112,221,050
Ensembl chr 2:112,207,745...112,221,050
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G |
Cybb |
cytochrome b-245 beta chain |
multiple interactions |
ISO |
rhodioloside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of CYBB protein]; sirtinol inhibits the reaction [rhodioloside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of CYBB protein]] |
CTD |
PMID:28851138 |
|
NCBI chr X:13,358,101...13,392,570
Ensembl chr X:13,359,430...13,392,586
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G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
multiple interactions |
ISO |
rhodioloside inhibits the reaction [furan results in increased expression of CYP2E1 protein] |
CTD |
PMID:34450210 |
|
NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
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G |
Cyp7a1 |
cytochrome P450 family 7 subfamily A member 1 |
multiple interactions |
ISO |
rhodioloside inhibits the reaction [furan results in decreased expression of CYP7A1 mRNA] |
CTD |
PMID:32251705 |
|
NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
multiple interactions |
ISO |
rhodioloside inhibits the reaction [furan results in increased expression of DDIT3 mRNA]; rhodioloside inhibits the reaction [furan results in increased expression of DDIT3 protein] |
CTD |
PMID:34450210 |
|
NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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G |
Ddit4 |
DNA-damage-inducible transcript 4 |
multiple interactions |
EXP |
rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in increased expression of DDIT4 mRNA]; rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in increased expression of DDIT4 protein] |
CTD |
PMID:24989011 |
|
NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
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G |
Eno2 |
enolase 2 |
multiple interactions increases expression |
ISO |
N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester promotes the reaction [rhodioloside results in increased expression of ENO2 mRNA]; NOG protein inhibits the reaction [rhodioloside results in increased expression of ENO2 mRNA]; NOG protein inhibits the reaction [rhodioloside results in increased expression of ENO2 protein] rhodioloside results in increased expression of ENO2 mRNA; rhodioloside results in increased expression of ENO2 protein |
CTD |
PMID:24929042 |
|
NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980
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G |
Ern1 |
endoplasmic reticulum to nucleus signaling 1 |
multiple interactions |
ISO |
rhodioloside inhibits the reaction [furan results in increased phosphorylation of ERN1 protein] |
CTD |
PMID:34450210 |
|
NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
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|
G |
Fgf19 |
fibroblast growth factor 19 |
multiple interactions |
ISO |
[furan co-treated with rhodioloside] results in increased expression of FGF15 mRNA |
CTD |
PMID:32251705 |
|
NCBI chr 1:200,056,526...200,060,980
Ensembl chr 1:200,056,644...200,060,287
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|
G |
Fn1 |
fibronectin 1 |
multiple interactions |
EXP |
rhodioloside inhibits the reaction [Glucose results in increased expression of FN1 mRNA] |
CTD |
PMID:29031534 |
|
NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
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G |
Hes1 |
hes family bHLH transcription factor 1 |
decreases expression |
ISO |
rhodioloside results in decreased expression of HES1 mRNA |
CTD |
PMID:24929042 |
|
NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192
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G |
Hif1a |
hypoxia inducible factor 1 subunit alpha |
multiple interactions |
EXP |
[rhodioloside co-treated with cobaltous chloride co-treated with NGF protein] results in decreased expression of HIF1A mRNA; R 59949 inhibits the reaction [rhodioloside promotes the reaction [cobaltous chloride results in increased expression of and affects the localization of HIF1A protein]]; rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in increased expression of HIF1A protein]; rhodioloside promotes the reaction [cobaltous chloride results in increased expression of and affects the localization of HIF1A protein] |
CTD |
PMID:21499890 PMID:24989011 |
|
NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
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G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
multiple interactions |
ISO |
rhodioloside inhibits the reaction [furan results in increased expression of HSPA5 mRNA]; rhodioloside inhibits the reaction [furan results in increased expression of HSPA5 protein] |
CTD |
PMID:34450210 |
|
NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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G |
Il18 |
interleukin 18 |
multiple interactions |
ISO |
rhodioloside inhibits the reaction [furan results in increased expression of IL18 mRNA]; rhodioloside inhibits the reaction [furan results in increased expression of IL18 protein] |
CTD |
PMID:34450210 |
|
NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
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G |
Il1b |
interleukin 1 beta |
multiple interactions |
EXP ISO |
rhodioloside inhibits the reaction [Isoflurane results in increased expression of IL1B protein] rhodioloside inhibits the reaction [furan results in increased expression of IL1B mRNA]; rhodioloside inhibits the reaction [furan results in increased expression of IL1B protein]; rhodioloside results in decreased secretion of and results in decreased expression of IL1B protein |
CTD |
PMID:28084090 PMID:34450210 PMID:37530723 |
|
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il6 |
interleukin 6 |
multiple interactions |
ISO |
rhodioloside inhibits the reaction [furan results in increased expression of IL6 mRNA]; rhodioloside results in decreased secretion of and results in decreased expression of IL6 protein |
CTD |
PMID:34450210 PMID:37530723 |
|
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Map2 |
microtubule-associated protein 2 |
multiple interactions increases expression |
ISO |
N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester promotes the reaction [rhodioloside results in increased expression of MAP2 mRNA]; NOG protein inhibits the reaction [rhodioloside results in increased expression of MAP2 mRNA]; NOG protein inhibits the reaction [rhodioloside results in increased expression of MAP2 protein] rhodioloside results in increased expression of MAP2 mRNA; rhodioloside results in increased expression of MAP2 protein |
CTD |
PMID:24929042 |
|
NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809
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G |
Map3k5 |
mitogen-activated protein kinase kinase kinase 5 |
multiple interactions |
ISO |
rhodioloside inhibits the reaction [furan results in increased phosphorylation of MAP3K5 protein] |
CTD |
PMID:34450210 |
|
NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions |
ISO |
rhodioloside inhibits the reaction [furan results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:34450210 |
|
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions |
ISO |
rhodioloside inhibits the reaction [furan results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:34450210 |
|
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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|
G |
Mapk8 |
mitogen-activated protein kinase 8 |
multiple interactions |
ISO |
rhodioloside inhibits the reaction [furan results in increased phosphorylation of MAPK8 protein] |
CTD |
PMID:34450210 |
|
NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
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G |
Mtor |
mechanistic target of rapamycin kinase |
multiple interactions |
EXP |
Everolimus inhibits the reaction [rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in decreased phosphorylation of MTOR protein]]; rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in decreased phosphorylation of MTOR protein] |
CTD |
PMID:24989011 |
|
NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
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G |
Nfkbia |
NFKB inhibitor alpha |
multiple interactions |
ISO |
rhodioloside inhibits the reaction [furan results in increased phosphorylation of NFKBIA protein] |
CTD |
PMID:34450210 |
|
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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G |
Ngf |
nerve growth factor |
multiple interactions |
EXP |
[rhodioloside co-treated with cobaltous chloride co-treated with NGF protein] results in decreased expression of HIF1A mRNA; Everolimus inhibits the reaction [rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in decreased phosphorylation of MTOR protein]]; Everolimus inhibits the reaction [rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in decreased phosphorylation of RPS6KB1 protein]]; rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in decreased phosphorylation of MTOR protein]; rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in decreased phosphorylation of RPS6KB1 protein]; rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in increased expression of DDIT4 mRNA]; rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in increased expression of DDIT4 protein]; rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in increased expression of HIF1A protein] |
CTD |
PMID:24989011 |
|
NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
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G |
Nlrp3 |
NLR family, pyrin domain containing 3 |
multiple interactions |
EXP ISO |
rhodioloside inhibits the reaction [Glucose results in increased expression of NLRP3 protein] rhodioloside inhibits the reaction [furan results in increased expression of NLRP3 protein] |
CTD |
PMID:29031534 PMID:34450210 |
|
NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
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G |
Nog |
noggin |
multiple interactions |
ISO |
NOG protein inhibits the reaction [rhodioloside results in increased expression of ENO2 mRNA]; NOG protein inhibits the reaction [rhodioloside results in increased expression of ENO2 protein]; NOG protein inhibits the reaction [rhodioloside results in increased expression of MAP2 mRNA]; NOG protein inhibits the reaction [rhodioloside results in increased expression of MAP2 protein]; NOG protein inhibits the reaction [rhodioloside results in increased expression of TUBB3 mRNA]; NOG protein inhibits the reaction [rhodioloside results in increased expression of TUBB3 protein] |
CTD |
PMID:24929042 |
|
NCBI chr10:74,128,712...74,130,339
Ensembl chr10:74,128,712...74,130,339
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G |
Notch1 |
notch receptor 1 |
decreases expression |
ISO |
rhodioloside results in decreased expression of NOTCH1 mRNA |
CTD |
PMID:24929042 |
|
NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
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G |
Nox1 |
NADPH oxidase 1 |
multiple interactions |
ISO EXP |
rhodioloside inhibits the reaction [Doxorubicin results in increased expression of NOX1 mRNA] |
CTD |
PMID:24072175 |
|
NCBI chr X:97,279,058...97,332,291
Ensembl chr X:97,279,056...97,302,236
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G |
Nr0b2 |
nuclear receptor subfamily 0, group B, member 2 |
multiple interactions |
ISO |
rhodioloside inhibits the reaction [furan results in increased expression of NR0B2 mRNA] |
CTD |
PMID:32251705 |
|
NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609
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G |
Nr1h4 |
nuclear receptor subfamily 1, group H, member 4 |
multiple interactions |
ISO |
rhodioloside affects the reaction [furan affects the expression of NR1H4 mRNA] |
CTD |
PMID:32251705 |
|
NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
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G |
Ocln |
occludin |
multiple interactions |
ISO |
rhodioloside affects the reaction [furan results in decreased expression of OCLN protein]; rhodioloside inhibits the reaction [Streptozocin results in decreased expression of OCLN protein] |
CTD |
PMID:31682803 PMID:32251705 |
|
NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150
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G |
Prkaa1 |
protein kinase AMP-activated catalytic subunit alpha 1 |
multiple interactions |
ISO |
rhodioloside results in increased phosphorylation of [PRKAA1 protein binds to PRKAA2 protein] |
CTD |
PMID:37530723 |
|
NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
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G |
Prkaa2 |
protein kinase AMP-activated catalytic subunit alpha 2 |
multiple interactions |
ISO |
rhodioloside results in increased phosphorylation of [PRKAA1 protein binds to PRKAA2 protein] |
CTD |
PMID:37530723 |
|
NCBI chr 5:119,807,992...119,879,987
Ensembl chr 5:119,813,226...119,879,543
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G |
Prkar2b |
protein kinase cAMP-dependent type II regulatory subunit beta |
multiple interactions |
EXP |
rhodioloside inhibits the reaction [[Oxygen co-treated with Glucose deficiency] results in decreased expression of PRKAR2B protein] |
CTD |
PMID:24726522 |
|
NCBI chr 6:48,563,659...48,653,933
Ensembl chr 6:48,563,662...48,653,933
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G |
Pycard |
PYD and CARD domain containing |
multiple interactions |
EXP ISO |
rhodioloside inhibits the reaction [Glucose results in increased expression of PYCARD protein] rhodioloside inhibits the reaction [furan results in increased expression of PYCARD protein] |
CTD |
PMID:29031534 PMID:34450210 |
|
NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
EXP ISO |
rhodioloside inhibits the reaction [cobaltous chloride results in increased expression of RELA protein] rhodioloside inhibits the reaction [furan results in increased phosphorylation of RELA protein] |
CTD |
PMID:21499890 PMID:34450210 |
|
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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G |
Rps6kb1 |
ribosomal protein S6 kinase B1 |
multiple interactions |
EXP |
Everolimus inhibits the reaction [rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in decreased phosphorylation of RPS6KB1 protein]]; rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in decreased phosphorylation of RPS6KB1 protein] |
CTD |
PMID:24989011 |
|
NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
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|
G |
Runx2 |
RUNX family transcription factor 2 |
increases expression increases activity |
ISO |
rhodioloside results in increased expression of RUNX2 mRNA rhodioloside results in increased activity of RUNX2 protein |
CTD |
PMID:24055767 |
|
NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
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G |
Sirt1 |
sirtuin 1 |
multiple interactions |
ISO |
rhodioloside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of and results in decreased activity of SIRT1 protein] |
CTD |
PMID:28851138 |
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NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
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G |
Smad1 |
SMAD family member 1 |
multiple interactions increases expression |
ISO |
rhodioloside results in increased phosphorylation of and results in increased expression of SMAD1 protein rhodioloside results in increased expression of SMAD1 mRNA |
CTD |
PMID:24929042 |
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NCBI chr19:28,513,130...28,573,665
Ensembl chr19:28,513,131...28,573,651
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G |
Smad5 |
SMAD family member 5 |
increases expression multiple interactions |
ISO |
rhodioloside results in increased expression of SMAD5 mRNA rhodioloside results in increased phosphorylation of and results in increased expression of SMAD5 protein |
CTD |
PMID:24929042 |
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NCBI chr17:7,862,332...7,891,678
Ensembl chr17:7,864,720...7,891,634
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G |
Smad9 |
SMAD family member 9 |
increases expression multiple interactions |
ISO |
rhodioloside results in increased expression of SMAD9 mRNA rhodioloside results in increased phosphorylation of and results in increased expression of SMAD9 protein |
CTD |
PMID:24929042 |
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NCBI chr 2:138,956,326...139,006,315
Ensembl chr 2:138,986,471...139,006,307
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G |
Sod1 |
superoxide dismutase 1 |
multiple interactions |
ISO |
rhodioloside inhibits the reaction [furan results in decreased expression of SOD1 mRNA] |
CTD |
PMID:34450210 |
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NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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G |
Sod2 |
superoxide dismutase 2 |
increases expression |
ISO EXP |
rhodioloside results in increased expression of SOD2 mRNA; rhodioloside results in increased expression of SOD2 protein |
CTD |
PMID:24072175 |
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NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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G |
Sp7 |
Sp7 transcription factor |
increases expression |
ISO |
rhodioloside results in increased expression of SP7 mRNA |
CTD |
PMID:24055767 |
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NCBI chr 7:133,484,609...133,494,788
Ensembl chr 7:133,484,609...133,494,847
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G |
Spp1 |
secreted phosphoprotein 1 |
increases expression |
ISO |
rhodioloside results in increased expression of SPP1 mRNA |
CTD |
PMID:24055767 |
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NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
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G |
Tgfb1 |
transforming growth factor, beta 1 |
multiple interactions |
EXP |
rhodioloside inhibits the reaction [Paraquat results in increased expression of TGFB1 mRNA]; rhodioloside inhibits the reaction [Paraquat results in increased expression of TGFB1 protein] |
CTD |
PMID:25674253 |
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NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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G |
Tjp1 |
tight junction protein 1 |
multiple interactions |
ISO |
rhodioloside inhibits the reaction [furan results in decreased expression of TJP1 protein]; rhodioloside inhibits the reaction [Streptozocin results in decreased expression of TJP1 protein] |
CTD |
PMID:31682803 PMID:32251705 |
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NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432
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G |
Tnf |
tumor necrosis factor |
multiple interactions |
EXP ISO |
rhodioloside inhibits the reaction [Isoflurane results in increased expression of TNF protein] rhodioloside inhibits the reaction [furan results in increased expression of TNF mRNA]; rhodioloside results in decreased secretion of and results in decreased expression of TNF protein |
CTD |
PMID:28084090 PMID:34450210 PMID:37530723 |
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Traf2 |
Tnf receptor-associated factor 2 |
multiple interactions |
ISO |
rhodioloside inhibits the reaction [furan results in increased expression of TRAF2 protein] |
CTD |
PMID:34450210 |
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NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538
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G |
Tubb3 |
tubulin, beta 3 class III |
multiple interactions increases expression |
ISO |
N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester promotes the reaction [rhodioloside results in increased expression of TUBB3 mRNA]; NOG protein inhibits the reaction [rhodioloside results in increased expression of TUBB3 mRNA]; NOG protein inhibits the reaction [rhodioloside results in increased expression of TUBB3 protein] rhodioloside results in increased expression of TUBB3 mRNA; rhodioloside results in increased expression of TUBB3 protein |
CTD |
PMID:24929042 |
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NCBI chr19:51,457,187...51,466,243
Ensembl chr19:51,457,184...51,466,243
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G |
Txnip |
thioredoxin interacting protein |
multiple interactions decreases expression |
EXP ISO |
rhodioloside inhibits the reaction [Glucose results in increased expression of TXNIP protein] rhodioloside results in decreased expression of TXNIP protein |
CTD |
PMID:29031534 PMID:37530723 |
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NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
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G |
Xbp1 |
X-box binding protein 1 |
multiple interactions |
ISO |
rhodioloside inhibits the reaction [furan results in increased expression of XBP1 protein] |
CTD |
PMID:34450210 |
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NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
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