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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:4-methoxytyramine
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Accession:CHEBI:89641 term browser browse the term
Definition:A monomethoxybenzene that is dopamine in which the hydroxy group at position 4 is replaced by a methoxy group.
Synonyms:related_synonym: 2-(3-hydroxy-4-methoxyphenyl)ethylamine;   3-Hydroxy-4-methoxyphenethylamine;   3-hydroxy-4-methoxyphenylethylamine;   4-O-Methyldopamine;   4-methoxy-3-hydroxyphenethylamine;   4-methoxy-3-hydroxyphenylethylamine;   4-methoxy-m-tyramine;   4-methoxydopamine;   5-(2-aminoethyl)-2-methoxyphenol;   5-(2-aminoethyl)guaiacol;   5-Hydroxy-4-methoxy-Benzeneethanamine;   Formula=C9H13NO2;   InChI=1S/C9H13NO2/c1-12-9-3-2-7(4-5-10)6-8(9)11/h2-3,6,11H,4-5,10H2,1H3;   InChIKey=WJXQFVMTIGJBFX-UHFFFAOYSA-N;   SMILES=COC1=C(O)C=C(CCN)C=C1;   p-methoxydopamine
 xref: CAS:3213-30-7;   FooDB:FDB028818;   HMDB:HMDB0012162
 xref_mesh: MESH:C031065
 xref: PMID:10850391;   PMID:12495814;   PMID:12777961;   PMID:1400795;   PMID:18077578;   PMID:21090691;   PMID:3860259;   PMID:404066;   PMID:4403838;   PMID:541405;   PMID:6060260;   PMID:6113986;   PMID:6518609;   PMID:6824696;   PMID:8113819
 cyclic_relationship: is_conjugate_base_of CHEBI:192993


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4-methoxytyramine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Taar1 trace-amine-associated receptor 1 increases activity
multiple interactions		 ISO 3-hydroxy-4-methoxyphenethylamine results in increased activity of TAAR1 protein
[3-hydroxy-4-methoxyphenethylamine results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP		 CTD PMID:19725810 NCBI chr 1:21,517,742...21,518,740
Ensembl chr 1:21,517,258...21,532,084 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19911
    role 19854
      biological role 19852
        molecular messenger 18686
          monoamine molecular messenger 612
            catecholamine 558
              dopamine 379
                4-methoxytyramine 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19911
    subatomic particle 19909
      composite particle 19909
        hadron 19880
          baryon 19880
            nucleon 19909
              atomic nucleus 19880
                atom 19909
                  main group element atom 19849
                    main group molecular entity 19849
                      s-block molecular entity 19681
                        hydrogen molecular entity 19662
                          hydrides 19167
                            inorganic hydride 18182
                              pnictogen hydride 18172
                                nitrogen hydride 18085
                                  azane 17866
                                    ammonia 17865
                                      organic amino compound 17888
                                        aralkylamino compound 1027
                                          monoamine 612
                                            monoamine molecular messenger 612
                                              catecholamine 558
                                                dopamine 379
                                                  4-methoxytyramine 1
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