CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: Monobutylphthalate
Accession: CHEBI:88522
browse the term
Definition: A phthalic acid monoester that has formula C12H14O4.
Synonyms: related_synonym: -N-butyl-phthalate; 2-(Butoxycarbonyl)benzoate; 2-(Butoxycarbonyl)benzoic acid; Butyl hydrogen phthalate; Formula=C12H14O4; InChI=1S/C12H14O4/c1-2-3-8-16-12(15)10-7-5-4-6-9(10)11(13)14/h4-7H,2-3,8H2,1H3,(H,13,14); InChIKey=YZBOVSFWWNVKRJ-UHFFFAOYSA-N; MONOBUTYL PHTHALATE; Mono-N-butyl phthalate; Phthalic acid Monobutyl Ester; SMILES=C=1C=CC(=C(C1)C(=O)OCCCC)C(=O)O
xref: CAS:131-70-4; HMDB:HMDB0013247
xref_mesh: MESH:C028577
xref: PMID:11049818
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Aagab
alpha- and gamma-adaptin binding protein
decreases expression
EXP
monobutyl phthalate results in decreased expression of AAGAB mRNA
CTD
PMID:29162477
NCBI chr 8:64,083,343...64,121,903
Ensembl chr 8:64,083,380...64,121,900
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Abca3
ATP binding cassette subfamily A member 3
decreases expression
EXP
monobutyl phthalate results in decreased expression of ABCA3 mRNA
CTD
PMID:29162477
NCBI chr10:13,382,439...13,439,748
Ensembl chr10:13,382,540...13,439,745
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Acadl
acyl-CoA dehydrogenase, long chain
increases expression
ISO
monobutyl phthalate results in increased expression of ACADL mRNA
CTD
PMID:36736749
NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:68,333,980...68,372,220
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Acadm
acyl-CoA dehydrogenase medium chain
increases expression
ISO
monobutyl phthalate results in increased expression of ACADM mRNA
CTD
PMID:36736749
NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147
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Acot1
acyl-CoA thioesterase 1
increases expression
EXP
monobutyl phthalate results in increased expression of ACOT1 mRNA
CTD
PMID:29162477
NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163
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Acsl4
acyl-CoA synthetase long-chain family member 4
multiple interactions increases expression
ISO
angoline inhibits the reaction [monobutyl phthalate results in increased expression of ACSL4 protein]; ferrostatin-1 inhibits the reaction [monobutyl phthalate results in increased expression of ACSL4 protein]
CTD
PMID:37121744
NCBI chr X:105,942,794...106,006,573
Ensembl chr X:105,942,799...106,006,427
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Acta1
actin, alpha 1, skeletal muscle
increases expression decreases expression
ISO
monobutyl phthalate results in increased expression of ACTA1 protein monobutyl phthalate results in decreased expression of ACTA1 mRNA
CTD
PMID:20553848 PMID:35278568
NCBI chr19:51,883,709...51,886,735
Ensembl chr19:51,883,715...51,886,742
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Actb
actin, beta
increases expression
ISO
monobutyl phthalate results in increased expression of ACTB protein
CTD
PMID:20553848
NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
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Actg2
actin gamma 2, smooth muscle
decreases expression
ISO
monobutyl phthalate results in decreased expression of ACTG2 mRNA
CTD
PMID:35278568
NCBI chr 4:116,021,832...116,046,475
Ensembl chr 4:116,021,832...116,046,465
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Acvrl1
activin A receptor like type 1
increases expression
ISO
monobutyl phthalate results in increased expression of ACVRL1 mRNA
CTD
PMID:35278568
NCBI chr 7:132,239,200...132,256,592
Ensembl chr 7:132,239,729...132,256,591
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Adarb1
adenosine deaminase, RNA-specific, B1
decreases expression
EXP
monobutyl phthalate results in decreased expression of ADARB1 mRNA
CTD
PMID:20864626
NCBI chr20:11,222,569...11,350,854
Ensembl chr20:11,222,583...11,350,852
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Adgrf1
adhesion G protein-coupled receptor F1
increases expression
EXP
monobutyl phthalate results in increased expression of ADGRF1 mRNA
CTD
PMID:29162477
NCBI chr 9:17,661,258...17,696,359
Ensembl chr 9:17,660,930...17,711,704
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Adgrl3
adhesion G protein-coupled receptor L3
increases expression
EXP
monobutyl phthalate results in increased expression of ADGRL3 mRNA
CTD
PMID:29162477
NCBI chr14:26,336,320...27,104,060
Ensembl chr14:26,368,277...27,105,860
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Adh1c
alcohol dehydrogenase 1C (class I), gamma polypeptide
multiple interactions
ISO
[Dibutyl Phthalate results in increased abundance of monobutyl phthalate] which affects the expression of ADH1 mRNA
CTD
PMID:34175954
NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892
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Adprs
ADP-ribosylserine hydrolase
decreases expression
EXP
monobutyl phthalate results in decreased expression of ADPRS mRNA
CTD
PMID:29162477
NCBI chr 5:138,614,022...138,619,296
Ensembl chr 5:138,614,022...138,619,296
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Ahr
aryl hydrocarbon receptor
affects expression
ISO
monobutyl phthalate affects the expression of AHR mRNA
CTD
PMID:28381288
NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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Ajuba
ajuba LIM protein
affects expression
EXP
monobutyl phthalate affects the expression of AJUBA mRNA
CTD
PMID:20864626
NCBI chr15:28,019,775...28,031,537
Ensembl chr15:28,019,778...28,030,021
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Akt1
AKT serine/threonine kinase 1
affects expression increases phosphorylation
EXP ISO
monobutyl phthalate affects the expression of AKT1 mRNA monobutyl phthalate results in increased phosphorylation of AKT1 protein
CTD
PMID:20864626 PMID:35278568
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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Aldh1a1
aldehyde dehydrogenase 1 family, member A1
multiple interactions
ISO
[Dibutyl Phthalate results in increased abundance of monobutyl phthalate] which affects the expression of ALDH1A1 mRNA
CTD
PMID:34175954
NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
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Aldh9a1
aldehyde dehydrogenase 9 family, member A1
increases expression
EXP
monobutyl phthalate results in increased expression of ALDH9A1 mRNA
CTD
PMID:20864626
NCBI chr13:79,505,738...79,522,539
Ensembl chr13:79,505,695...79,540,568
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Alox15
arachidonate 15-lipoxygenase
affects expression
ISO
monobutyl phthalate affects the expression of ALOX15 mRNA
CTD
PMID:19162170
NCBI chr10:55,060,169...55,068,885
Ensembl chr10:55,060,412...55,068,874
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Amer1
APC membrane recruitment protein 1
increases expression
EXP
monobutyl phthalate results in increased expression of AMER1 mRNA
CTD
PMID:29162477
NCBI chr X:60,300,595...60,316,480
Ensembl chr X:60,295,751...60,316,440
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Ankrd36
ankyrin repeat domain 36
increases expression
EXP
monobutyl phthalate results in increased expression of ANKRD36 mRNA
CTD
PMID:29162477
NCBI chr14:80,451,699...80,568,458
Ensembl chr14:80,451,738...80,516,513
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Ankrd37
ankyrin repeat domain 37
decreases expression
EXP
monobutyl phthalate results in decreased expression of ANKRD37 mRNA
CTD
PMID:20864626
NCBI chr16:46,268,933...46,271,971
Ensembl chr16:46,268,443...46,271,963
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Anxa5
annexin A5
increases expression
ISO
monobutyl phthalate results in increased expression of ANXA5 protein
CTD
PMID:20553848
NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369
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Apc
APC regulator of WNT signaling pathway
affects expression
EXP
monobutyl phthalate affects the expression of APC mRNA
CTD
PMID:20864626
NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696
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Apol2
apolipoprotein L2
increases expression
EXP
monobutyl phthalate results in increased expression of APOL3 mRNA
CTD
PMID:29162477
NCBI chr 7:109,331,367...109,338,632
Ensembl chr 7:109,331,392...109,338,558
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Ar
androgen receptor
multiple interactions increases activity decreases expression
ISO
Flutamide inhibits the reaction [monobutyl phthalate results in increased activity of AR protein]; monobutyl phthalate inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein] monobutyl phthalate results in decreased expression of AR protein
CTD
PMID:19643168 PMID:26922907
NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
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Armc2
armadillo repeat containing 2
decreases expression
ISO
monobutyl phthalate results in decreased expression of ARMC2 mRNA
CTD
PMID:35278568
NCBI chr20:45,395,859...45,501,808
Ensembl chr20:45,394,127...45,504,819
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Arrb2
arrestin, beta 2
increases expression
EXP
monobutyl phthalate results in increased expression of ARRB2 mRNA
CTD
PMID:20864626
NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850
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Art3
ADP-ribosyltransferase 3
decreases expression
ISO
monobutyl phthalate results in decreased expression of ART3 mRNA
CTD
PMID:35278568
NCBI chr14:15,637,230...15,719,442
Ensembl chr14:15,637,237...15,665,407
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Atp5f1e
ATP synthase F1 subunit epsilon
decreases expression
ISO
monobutyl phthalate results in decreased expression of ATP5E mRNA
CTD
PMID:35278568
NCBI chr 3:163,259,072...163,261,974
Ensembl chr 3:163,260,476...163,261,450
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Atp6v1h
ATPase H+ transporting V1 subunit H
affects expression
ISO
monobutyl phthalate affects the expression of ATP6V1H mRNA
CTD
PMID:21195148
NCBI chr 5:14,379,029...14,484,703
Ensembl chr 5:14,378,257...14,537,962
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Atpaf1
ATP synthase mitochondrial F1 complex assembly factor 1
decreases expression
EXP
monobutyl phthalate results in decreased expression of ATPAF1 mRNA
CTD
PMID:20864626
NCBI chr 5:129,265,789...129,292,463
Ensembl chr 5:129,266,404...129,293,556
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B3galt2
Beta-1,3-galactosyltransferase 2
increases expression
EXP
monobutyl phthalate results in increased expression of B3GALT2 mRNA
CTD
PMID:29162477
NCBI chr13:55,389,406...55,398,419
Ensembl chr13:55,389,406...55,398,419
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Barhl1
BarH-like homeobox 1
increases expression
EXP
monobutyl phthalate results in increased expression of BARHL1 mRNA
CTD
PMID:29162477
NCBI chr 3:12,241,327...12,248,649
Ensembl chr 3:12,241,327...12,248,649
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Bax
BCL2 associated X, apoptosis regulator
multiple interactions
ISO
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of BAX mRNA
CTD
PMID:35861251
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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Bbs10
Bardet-Biedl syndrome 10
decreases expression
EXP
monobutyl phthalate results in decreased expression of BBS10 mRNA
CTD
PMID:29162477
NCBI chr 7:46,751,028...46,754,132
Ensembl chr 7:46,750,993...46,754,141
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Bcl2
BCL2, apoptosis regulator
decreases methylation increases expression multiple interactions
ISO
monobutyl phthalate results in decreased methylation of BCL2 promoter monobutyl phthalate results in increased expression of BCL2 mRNA [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of BCL2 mRNA
CTD
PMID:35487445 PMID:35861251
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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Bmp10
bone morphogenetic protein 10
increases expression
EXP
monobutyl phthalate results in increased expression of BMP10 mRNA
CTD
PMID:29162477
NCBI chr 4:119,872,066...119,877,694
Ensembl chr 4:119,872,045...119,878,627
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Bnip1
BCL2 interacting protein 1
decreases expression
EXP
monobutyl phthalate results in decreased expression of BNIP1 mRNA
CTD
PMID:29162477
NCBI chr10:16,386,876...16,399,124
Ensembl chr10:16,386,841...16,399,157
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Brca1
BRCA1, DNA repair associated
affects expression
EXP
monobutyl phthalate affects the expression of BRCA1 mRNA
CTD
PMID:20864626
NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
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Bri3
brain protein I3
decreases expression
ISO
monobutyl phthalate results in decreased expression of BRI3 mRNA
CTD
PMID:35278568
NCBI chr12:10,341,007...10,364,655
Ensembl chr12:10,341,011...10,364,735
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C20h22orf15
similar to human chromosome 22 open reading frame 15
increases expression
EXP
monobutyl phthalate results in increased expression of C20H22ORF15 mRNA
CTD
PMID:29162477
NCBI chr20:12,723,160...12,725,864
Ensembl chr20:12,723,160...12,726,059
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C2cd5
C2 calcium-dependent domain containing 5
increases expression
EXP
monobutyl phthalate results in increased expression of C2CD5 mRNA
CTD
PMID:20864626
NCBI chr 4:175,969,544...176,055,597
Ensembl chr 4:175,969,545...176,055,558
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Caap1
caspase activity and apoptosis inhibitor 1
increases expression
EXP
monobutyl phthalate results in increased expression of CAAP1 mRNA
CTD
PMID:29162477
NCBI chr 5:109,313,253...109,414,323
Ensembl chr 5:109,361,912...109,414,314
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Cadm1
cell adhesion molecule 1
affects expression
ISO
monobutyl phthalate affects the expression of CADM1 mRNA
CTD
PMID:21195148
NCBI chr 8:47,847,836...48,178,703
Ensembl chr 8:47,847,325...48,182,833
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Calhm6
calcium homeostasis modulator family member 6
increases expression
EXP
monobutyl phthalate results in increased expression of CALHM6 mRNA
CTD
PMID:29162477
NCBI chr20:26,095,591...26,097,336
Ensembl chr20:26,095,592...26,097,278
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Calml3
calmodulin-like 3
increases expression
EXP
monobutyl phthalate results in increased expression of CALML3 mRNA
CTD
PMID:29162477
NCBI chr17:66,419,844...66,423,083
Ensembl chr17:66,419,882...66,423,175
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Car2
carbonic anhydrase 2
affects expression
ISO
monobutyl phthalate affects the expression of CAR2 mRNA
CTD
PMID:19162170
NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
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Car4
carbonic anhydrase 4
affects expression
ISO
monobutyl phthalate affects the expression of CAR4 mRNA
CTD
PMID:19162170
NCBI chr10:69,827,945...69,836,501
Ensembl chr10:69,827,945...69,836,501
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Casd1
CAS1 domain containing 1
affects expression
ISO
monobutyl phthalate affects the expression of CASD1 mRNA
CTD
PMID:20421339
NCBI chr 4:32,659,196...32,739,228
Ensembl chr 4:32,658,748...32,739,202
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Casp3
caspase 3
increases expression multiple interactions
ISO
monobutyl phthalate results in increased expression of CASP3 protein modified form [monobutyl phthalate co-treated with Ginsenosides metabolite] results in increased expression of CASP3 protein modified form; [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] affects the expression of CASP3 mRNA
CTD
PMID:30965081 PMID:35861251
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Casp8
caspase 8
multiple interactions
ISO
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of CASP8 mRNA
CTD
PMID:35861251
NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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Cat
catalase
increases activity multiple interactions
ISO
monobutyl phthalate results in increased activity of CAT protein [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of CAT mRNA
CTD
PMID:30965081 PMID:35861251
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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Cbr3
carbonyl reductase 3
affects expression
ISO
monobutyl phthalate affects the expression of CBR3 mRNA
CTD
PMID:20421339
NCBI chr11:33,008,615...33,016,877
Ensembl chr11:33,008,615...33,016,875
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Cbs
cystathionine beta synthase
affects expression
ISO
monobutyl phthalate affects the expression of CBS mRNA
CTD
PMID:21195148
NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764
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Cby2
chibby family member 2
increases expression
EXP
monobutyl phthalate results in increased expression of CBY2 mRNA
CTD
PMID:29162477
NCBI chr15:50,909,435...51,004,449
Ensembl chr15:50,909,436...50,934,633
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Ccdc163
coiled-coil domain containing 163
multiple interactions
ISO
[mono(2-ethyl-5-hydroxyhexyl) phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono(2-ethyl-5-oxohexyl)phthalate co-treated with 2-ethyl-5-carboxypentyl phthalate co-treated with mono-isobutyl phthalate co-treated with mono-benzyl phthalate co-treated with monoethyl phthalate co-treated with monobutyl phthalate] affects the expression of CCDC163 mRNA
CTD
PMID:37160244
NCBI chr 5:130,172,014...130,178,934
Ensembl chr 5:130,172,774...130,178,929
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Ccdc174
coiled-coil domain containing 174
decreases expression
EXP
monobutyl phthalate results in decreased expression of CCDC174 mRNA
CTD
PMID:20864626
NCBI chr 4:124,392,183...124,419,035
Ensembl chr 4:124,392,274...124,419,035
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Ccdc180
coiled-coil domain containing 180
increases expression
EXP
monobutyl phthalate results in increased expression of CCDC180 mRNA
CTD
PMID:29162477
NCBI chr 5:60,154,883...60,223,508
Ensembl chr 5:60,154,910...60,223,522
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Ccdc96
coiled-coil domain containing 96
affects expression
ISO
monobutyl phthalate affects the expression of CCDC96 mRNA
CTD
PMID:21195148
NCBI chr14:74,276,568...74,279,072
Ensembl chr14:74,276,960...74,278,888
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Ccl2
C-C motif chemokine ligand 2
increases expression
ISO
monobutyl phthalate results in increased expression of CCL2 mRNA
CTD
PMID:32015430
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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Ccnc
cyclin C
affects expression
EXP
monobutyl phthalate affects the expression of CCNC mRNA
CTD
PMID:20864626
NCBI chr 5:35,266,828...35,284,943
Ensembl chr 5:35,266,823...35,296,584
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Ccnd1
cyclin D1
affects expression
ISO
monobutyl phthalate affects the expression of CCND1 mRNA
CTD
PMID:21195148
NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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Ccnd2
cyclin D2
affects expression
ISO
monobutyl phthalate affects the expression of CCND2 mRNA
CTD
PMID:19162170
NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
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Ccno
cyclin O
affects expression
ISO
monobutyl phthalate affects the expression of CCNO mRNA
CTD
PMID:21195148
NCBI chr 2:44,630,873...44,633,912
Ensembl chr 2:44,626,369...44,633,914
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Ccr7
C-C motif chemokine receptor 7
multiple interactions
ISO
[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-benzyl phthalate co-treated with monobutyl phthalate] results in increased expression of CCR7 mRNA
CTD
PMID:30398665
NCBI chr10:84,098,193...84,108,309
Ensembl chr10:84,097,381...84,108,309
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Ccz1
CCZ1 homolog, vacuolar protein trafficking and biogenesis associated
decreases expression
EXP
monobutyl phthalate results in decreased expression of CCZ1 mRNA
CTD
PMID:20864626
NCBI chr12:10,601,066...10,624,608
Ensembl chr12:10,601,056...10,624,608
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Cd109
CD109 molecule
affects expression
ISO
monobutyl phthalate affects the expression of CD109 mRNA
CTD
PMID:21195148
NCBI chr 8:79,454,480...79,569,195
Ensembl chr 8:79,454,480...79,569,194
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Cd160
CD160 molecule
increases expression
EXP
monobutyl phthalate results in increased expression of CD160 mRNA
CTD
PMID:29162477
NCBI chr 2:184,340,820...184,383,421
Ensembl chr 2:184,340,599...184,375,834
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Cd163
CD163 molecule
multiple interactions
ISO
[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-benzyl phthalate co-treated with monobutyl phthalate] results in decreased expression of CD163 mRNA
CTD
PMID:30398665
NCBI chr 4:157,085,080...157,118,470
Ensembl chr 4:157,085,093...157,117,878
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Cd24
CD24 molecule
affects expression
ISO
monobutyl phthalate affects the expression of CD24A mRNA
CTD
PMID:21195148
NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662
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Cd36
CD36 molecule
increases expression multiple interactions affects expression
ISO
monobutyl phthalate results in increased expression of CD36 mRNA GW 6471 inhibits the reaction [monobutyl phthalate results in increased expression of CD36 mRNA] monobutyl phthalate affects the expression of CD36 protein
CTD
PMID:35421560 PMID:36736749
NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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Cd40
CD40 molecule
affects expression
ISO
monobutyl phthalate affects the expression of CD40 mRNA
CTD
PMID:21195148
NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
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Cd68
Cd68 molecule
increases expression
ISO
monobutyl phthalate results in increased expression of CD68 mRNA
CTD
PMID:32015430
NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697
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Cd74
CD74 molecule
increases expression
ISO
monobutyl phthalate results in increased expression of CD74 mRNA
CTD
PMID:35278568
NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003
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Cdc25b
cell division cycle 25B
increases expression affects expression
EXP
monobutyl phthalate results in increased expression of CDC25B mRNA monobutyl phthalate affects the expression of CDC25B mRNA
CTD
PMID:20864626
NCBI chr 3:118,407,127...118,417,272
Ensembl chr 3:118,407,128...118,417,272
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Cdca7
cell division cycle associated 7
affects expression
ISO
monobutyl phthalate affects the expression of CDCA7 mRNA
CTD
PMID:20421339
NCBI chr 3:57,322,718...57,333,353
Ensembl chr 3:57,322,708...57,333,353
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Cdh1
cadherin 1
increases expression
EXP
monobutyl phthalate results in increased expression of CDH1 mRNA
CTD
PMID:20864626
NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
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Cdh2
cadherin 2
decreases expression
ISO
monobutyl phthalate results in decreased expression of CDH2 protein
CTD
PMID:26922907
NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
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Cdh26
cadherin 26
increases expression
EXP
monobutyl phthalate results in increased expression of CDH26 mRNA
CTD
PMID:29162477
NCBI chr 3:165,520,523...165,573,191
Ensembl chr 3:165,520,439...165,572,149
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Cdk2
cyclin dependent kinase 2
affects expression
EXP
monobutyl phthalate affects the expression of CDK2 mRNA
CTD
PMID:20864626
NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
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Cdkn2a
cyclin-dependent kinase inhibitor 2A
decreases expression increases methylation multiple interactions
ISO
monobutyl phthalate results in decreased expression of CDKN2A mRNA monobutyl phthalate results in increased methylation of CDKN2A promoter [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CDKN2A mRNA
CTD
PMID:35487445 PMID:35861251
NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
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Cdyl2
chromodomain Y-like 2
increases expression
EXP
monobutyl phthalate results in increased expression of CDYL2 mRNA
CTD
PMID:29162477
NCBI chr19:44,591,734...44,783,258
Ensembl chr19:44,597,459...44,783,022
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Cebpb
CCAAT/enhancer binding protein beta
decreases expression
ISO
monobutyl phthalate results in decreased expression of CEBPB mRNA
CTD
PMID:35278568
NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
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Cebpd
CCAAT/enhancer binding protein delta
decreases expression
ISO
monobutyl phthalate results in decreased expression of CEBPD mRNA
CTD
PMID:35278568
NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829
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Cenpl
centromere protein L
decreases expression
EXP
monobutyl phthalate results in decreased expression of CENPL mRNA
CTD
PMID:29162477
NCBI chr13:73,337,235...73,352,115
Ensembl chr13:73,337,257...73,352,114
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Cer1
cerberus 1, DAN family BMP antagonist
affects expression
ISO
monobutyl phthalate affects the expression of CER1 mRNA
CTD
PMID:19162170
NCBI chr 5:97,306,427...97,309,783
Ensembl chr 5:97,306,431...97,309,783
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Ces1c
carboxylesterase 1C
decreases expression
EXP
monobutyl phthalate results in decreased expression of ES2 mRNA
CTD
PMID:20864626
NCBI chr19:13,926,401...13,955,527
Ensembl chr19:13,926,260...13,955,524
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Cfl1
cofilin 1
increases expression
ISO
monobutyl phthalate results in increased expression of CFL1 protein
CTD
PMID:20553848
NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587
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Cga
glycoprotein hormones, alpha polypeptide
increases expression affects expression
ISO
monobutyl phthalate results in increased expression of CGA mRNA monobutyl phthalate affects the expression of CGA mRNA
CTD
PMID:28381288 PMID:29089286
NCBI chr 5:49,486,915...49,499,192
Ensembl chr 5:49,487,068...49,499,191
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Chac2
ChaC glutathione specific gamma-glutamylcyclotransferase 2
increases expression
EXP
monobutyl phthalate results in increased expression of CHAC2 mRNA
CTD
PMID:29162477
NCBI chr14:104,720,754...104,728,305
Ensembl chr14:104,720,758...104,728,301
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Chrd
chordin
affects expression
ISO
monobutyl phthalate affects the expression of CHRD mRNA
CTD
PMID:21195148
NCBI chr11:80,171,994...80,181,166
Ensembl chr11:80,171,994...80,180,673
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Chrna9
cholinergic receptor nicotinic alpha 9 subunit
affects expression
ISO
monobutyl phthalate affects the expression of CHRNA9 mRNA
CTD
PMID:21195148
NCBI chr14:42,235,218...42,241,939
Ensembl chr14:42,235,226...42,242,192
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Cldn22
claudin 22
increases expression
EXP
monobutyl phthalate results in increased expression of CLDN22 mRNA
CTD
PMID:29162477
NCBI chr16:44,422,344...44,423,370
Ensembl chr16:44,422,345...44,423,354
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Cldn4
claudin 4
increases expression
EXP
monobutyl phthalate results in increased expression of CLDN4 mRNA
CTD
PMID:29162477
NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436
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Clec6a-ps1
C-type lectin domain family 6, member A, pseudogene 1
decreases expression
EXP
monobutyl phthalate results in decreased expression of CLEC6A mRNA
CTD
PMID:29162477
NCBI chr 4:156,539,408...156,559,032
Ensembl chr 4:156,539,408...156,558,605 Ensembl chr 4:156,539,408...156,558,605
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Clic6
chloride intracellular channel 6
decreases expression
ISO
monobutyl phthalate results in decreased expression of CLIC6 protein
CTD
PMID:20553848
NCBI chr11:31,737,813...31,780,360
Ensembl chr11:31,737,813...31,780,061
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Cmklr1
chemerin chemokine-like receptor 1
affects expression
ISO
monobutyl phthalate affects the expression of CMKLR1 mRNA
CTD
PMID:19162170
NCBI chr12:42,974,462...43,027,321
Ensembl chr12:42,974,410...43,028,129
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Cnih3
cornichon family AMPA receptor auxiliary protein 3
decreases expression
ISO
monobutyl phthalate results in decreased expression of CNIH3 mRNA
CTD
PMID:35278568
NCBI chr13:93,016,707...93,208,168
Ensembl chr13:93,099,784...93,208,121
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Cnn1
calponin 1
increases expression
ISO
monobutyl phthalate results in increased expression of CNN1 mRNA
CTD
PMID:35278568
NCBI chr 8:20,632,434...20,641,097
Ensembl chr 8:20,632,338...20,641,098
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Cntnap4
contactin associated protein family member 4
increases expression
EXP
monobutyl phthalate results in increased expression of CNTNAP4 mRNA
CTD
PMID:29162477
NCBI chr19:40,568,684...40,861,879
Ensembl chr19:40,568,684...40,854,656
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Coa4
cytochrome c oxidase assembly factor 4 homolog
decreases expression
ISO
monobutyl phthalate results in decreased expression of COA4 mRNA
CTD
PMID:35278568
NCBI chr 1:154,882,199...154,885,445
Ensembl chr 1:154,882,155...154,888,174
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Coch
cochlin
decreases expression
EXP
monobutyl phthalate results in decreased expression of COCH mRNA
CTD
PMID:20864626
NCBI chr 6:69,031,139...69,045,124
Ensembl chr 6:69,031,167...69,045,109
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Col3a1
collagen type III alpha 1 chain
affects expression
ISO
monobutyl phthalate affects the expression of COL3A1 mRNA
CTD
PMID:19162170
NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
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Col9a3
collagen type IX alpha 3 chain
increases expression
EXP
monobutyl phthalate results in increased expression of COL9A3 mRNA
CTD
PMID:29162477
NCBI chr 3:167,711,776...167,734,468
Ensembl chr 3:167,711,840...167,734,465
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Cox6a2
cytochrome c oxidase subunit 6A2
increases expression
ISO
monobutyl phthalate results in increased expression of COX6A2 mRNA
CTD
PMID:35278568
NCBI chr 1:182,788,528...182,790,746
Ensembl chr 1:182,788,528...182,789,274
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Cox6c-ps1
cytochrome c oxidase subunit VIc, pseudogene
increases expression
EXP
monobutyl phthalate results in increased expression of COX6C-PS1 mRNA
CTD
PMID:29162477
NCBI chr19:52,192,612...52,193,470
Ensembl chr19:52,192,612...52,193,470
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Cpsf2
cleavage and polyadenylation specific factor 2
decreases expression
EXP
monobutyl phthalate results in decreased expression of CPSF2 mRNA
CTD
PMID:29162477
NCBI chr 6:121,123,941...121,152,756
Ensembl chr 6:121,120,569...121,151,921
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Cpt1a
carnitine palmitoyltransferase 1A
increases expression
ISO
monobutyl phthalate results in increased expression of CPT1A mRNA
CTD
PMID:36736749
NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
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Cpt1b
carnitine palmitoyltransferase 1B
increases expression
ISO
monobutyl phthalate results in increased expression of CPT1B mRNA
CTD
PMID:36736749
NCBI chr 7:120,491,354...120,500,833
Ensembl chr 7:120,491,354...120,500,404
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Cpt2
carnitine palmitoyltransferase 2
increases expression
ISO
monobutyl phthalate results in increased expression of CPT2 mRNA
CTD
PMID:36736749
NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095
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Cradd
CASP2 and RIPK1 domain containing adaptor with death domain
increases expression
ISO
monobutyl phthalate results in increased expression of CRADD mRNA
CTD
PMID:35278568
NCBI chr 7:29,940,240...29,952,907
Ensembl chr 7:29,798,586...29,952,907
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Crlf3
cytokine receptor-like factor 3
increases expression
EXP
monobutyl phthalate results in increased expression of CRLF3 mRNA
CTD
PMID:29162477
NCBI chr10:65,024,228...65,060,746
Ensembl chr10:65,023,388...65,060,670
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Crp
C-reactive protein
increases expression
ISO
monobutyl phthalate results in increased expression of CRP mRNA
CTD
PMID:32015430
NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178
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Cry1
cryptochrome circadian regulator 1
increases expression
EXP
monobutyl phthalate results in increased expression of CRY1 mRNA
CTD
PMID:29162477
NCBI chr 7:18,529,823...18,594,092
Ensembl chr 7:18,529,823...18,594,091
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Cryz
crystallin zeta
increases expression
EXP
monobutyl phthalate results in increased expression of CRYZ mRNA
CTD
PMID:29162477
NCBI chr 2:243,552,037...243,580,369
Ensembl chr 2:243,552,119...243,579,758
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Csnk2a2
casein kinase 2 alpha 2
decreases expression
EXP
monobutyl phthalate results in decreased expression of CSNK2A2 mRNA
CTD
PMID:20864626
NCBI chr19:9,556,443...9,596,080
Ensembl chr19:9,556,260...9,596,080
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Cth
cystathionine gamma-lyase
affects expression
ISO
monobutyl phthalate affects the expression of CTH mRNA
CTD
PMID:21195148
NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234
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Ctnnb1
catenin beta 1
affects expression increases expression multiple interactions
EXP ISO
monobutyl phthalate affects the expression of CTNNB1 mRNA monobutyl phthalate results in increased expression of CTNNB1 protein alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [monobutyl phthalate results in increased expression of CTNNB1 protein]
CTD
PMID:20864626 PMID:35278568 PMID:36736749
NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
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Ctnnd1
catenin delta 1
increases expression multiple interactions
ISO
monobutyl phthalate results in increased expression of CTNND1 protein alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [monobutyl phthalate results in increased expression of CTNND1 protein]
CTD
PMID:35278568
NCBI chr 3:69,683,328...69,734,550
Ensembl chr 3:69,683,313...69,734,516
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Ctxn3
cortexin 3
increases expression
EXP
monobutyl phthalate results in increased expression of CTXN3 mRNA
CTD
PMID:29162477
NCBI chr18:50,930,244...50,940,642
Ensembl chr18:50,930,235...50,940,641
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Cxcl10
C-X-C motif chemokine ligand 10
multiple interactions
ISO
[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-benzyl phthalate co-treated with monobutyl phthalate] results in increased expression of CXCL10 mRNA
CTD
PMID:30398665
NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
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Cxcr2
C-X-C motif chemokine receptor 2
increases expression
EXP
monobutyl phthalate results in increased expression of CXCR2 mRNA
CTD
PMID:29162477
NCBI chr 9:75,729,493...75,735,868
Ensembl chr 9:75,729,115...75,739,425
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Cxxc4
CXXC finger protein 4
increases expression
EXP
monobutyl phthalate results in increased expression of CXXC4 mRNA
CTD
PMID:29162477
NCBI chr 2:222,664,148...222,689,365
Ensembl chr 2:222,664,771...222,689,365
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Cyp11a1
cytochrome P450, family 11, subfamily a, polypeptide 1
increases expression decreases expression
ISO
monobutyl phthalate results in increased expression of CYP11A1 mRNA monobutyl phthalate results in decreased expression of CYP11A1 protein
CTD
PMID:29089286 PMID:34280466 PMID:36602389
NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
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Cyp17a1
cytochrome P450, family 17, subfamily a, polypeptide 1
decreases expression
EXP
monobutyl phthalate results in decreased expression of CYP17A1 mRNA
CTD
PMID:22511013
NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
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Cyp19a1
cytochrome P450, family 19, subfamily a, polypeptide 1
affects expression
ISO
monobutyl phthalate affects the expression of CYP19A1 mRNA
CTD
PMID:28381288
NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758
G
Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
decreases activity
EXP
monobutyl phthalate results in decreased activity of CYP1A1 protein
CTD
PMID:27432241
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
decreases activity
EXP
monobutyl phthalate results in decreased activity of CYP1A2 protein
CTD
PMID:27432241
NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
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Cyp1b1
cytochrome P450, family 1, subfamily b, polypeptide 1
multiple interactions
ISO
[Dibutyl Phthalate results in increased abundance of monobutyl phthalate] which affects the expression of CYP1B1 mRNA
CTD
PMID:34175954
NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
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Cyp26a1
cytochrome P450, family 26, subfamily a, polypeptide 1
affects expression
ISO
monobutyl phthalate affects the expression of CYP26A1 mRNA
CTD
PMID:19162170
NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204
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Cyp2b1
cytochrome P450, family 2, subfamily b, polypeptide 1
decreases activity
EXP
monobutyl phthalate results in decreased activity of CYP2B1 protein
CTD
PMID:27432241
NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
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Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
decreases activity
EXP
monobutyl phthalate results in decreased activity of CYP2E1 protein
CTD
PMID:27432241
NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
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Cyp2s1
cytochrome P450, family 2, subfamily s, polypeptide 1
affects expression
ISO
monobutyl phthalate affects the expression of CYP2S1 mRNA
CTD
PMID:20421339
NCBI chr 1:81,309,948...81,325,303
Ensembl chr 1:81,310,451...81,325,303
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Cyp3a62
cytochrome P450, family 3, subfamily a, polypeptide 62
decreases activity
EXP
monobutyl phthalate results in decreased activity of CYP3A62 protein
CTD
PMID:27432241
NCBI chr12:16,397,998...16,433,833
Ensembl chr12:16,397,998...16,433,833
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Cyp7b1
cytochrome P450 family 7 subfamily B member 1
decreases expression
EXP
monobutyl phthalate results in decreased expression of CYP7B1 mRNA
CTD
PMID:20864626
NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698
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Dapk1
death associated protein kinase 1
affects expression
ISO
monobutyl phthalate affects the expression of DAPK1 mRNA
CTD
PMID:20421339
NCBI chr17:3,930,223...4,090,991
Ensembl chr17:3,930,213...4,090,991
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Dazl
deleted in azoospermia-like
decreases expression
ISO
monobutyl phthalate results in decreased expression of DAZL mRNA
CTD
PMID:28496037
NCBI chr 9:10,695,593...10,712,330
Ensembl chr 9:10,695,592...10,712,323
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Dbndd1
dysbindin domain containing 1
increases expression
EXP
monobutyl phthalate results in increased expression of DBNDD1 mRNA
CTD
PMID:29162477
NCBI chr19:51,539,154...51,548,441
Ensembl chr19:51,539,148...51,548,444
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Dcaf11
DDB1 and CUL4 associated factor 11
decreases expression
EXP
monobutyl phthalate results in decreased expression of DCAF11 mRNA
CTD
PMID:20864626
NCBI chr15:29,046,744...29,057,450
Ensembl chr15:29,046,826...29,057,669
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Dcakd
dephospho-CoA kinase domain containing
multiple interactions
ISO
[mono(2-ethyl-5-hydroxyhexyl) phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono(2-ethyl-5-oxohexyl)phthalate co-treated with 2-ethyl-5-carboxypentyl phthalate co-treated with mono-isobutyl phthalate co-treated with mono-benzyl phthalate co-treated with monoethyl phthalate co-treated with monobutyl phthalate] affects the expression of DCAKD mRNA
CTD
PMID:37160244
NCBI chr10:87,957,738...87,989,002
Ensembl chr10:87,957,740...87,980,054
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Ddb1
damage-specific DNA binding protein 1
affects expression
EXP
monobutyl phthalate affects the expression of DDB1 mRNA
CTD
PMID:20864626
NCBI chr 1:207,252,890...207,278,685
Ensembl chr 1:207,252,890...207,278,676
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Ddhd1
DDHD domain containing 1
increases expression
EXP
monobutyl phthalate results in increased expression of DDHD1 mRNA
CTD
PMID:20864626
NCBI chr15:18,824,389...18,891,036
Ensembl chr15:18,824,394...18,890,952
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Ddit3
DNA-damage inducible transcript 3
increases expression
ISO
monobutyl phthalate results in increased expression of DDIT3 protein
CTD
PMID:38048874
NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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Ddo
D-aspartate oxidase
decreases expression
ISO
monobutyl phthalate results in decreased expression of DDO mRNA
CTD
PMID:35278568
NCBI chr20:44,090,823...44,109,962
Ensembl chr20:44,090,914...44,133,095
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Ddx31
DEAD-box helicase 31
decreases expression
EXP
monobutyl phthalate results in decreased expression of DDX31 mRNA
CTD
PMID:20864626
NCBI chr 3:12,172,829...12,238,392
Ensembl chr 3:12,172,836...12,238,873
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Dennd2c
DENN domain containing 2C
affects expression
ISO
monobutyl phthalate affects the expression of DENND2C mRNA
CTD
PMID:20421339
NCBI chr 2:190,622,357...190,690,489
Ensembl chr 2:190,622,940...190,690,488
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Depdc7
DEP domain containing 7
affects expression
ISO
monobutyl phthalate affects the expression of DEPDC7 mRNA
CTD
PMID:20421339
NCBI chr 3:91,099,111...91,121,152
Ensembl chr 3:91,099,835...91,121,124
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Derl3
derlin 3
affects expression
ISO
monobutyl phthalate affects the expression of DERL3 mRNA
CTD
PMID:21195148
NCBI chr20:12,754,490...12,768,454
Ensembl chr20:12,763,543...12,767,027
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Dgat1
diacylglycerol O-acyltransferase 1
increases expression
ISO
monobutyl phthalate results in increased expression of DGAT1 mRNA
CTD
PMID:36736749
NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299
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Dhrs3
dehydrogenase/reductase 3
decreases expression
ISO
monobutyl phthalate results in decreased expression of DHRS3 mRNA
CTD
PMID:35278568
NCBI chr 5:156,747,939...156,782,420
Ensembl chr 5:156,747,962...156,782,417
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Dicer1
dicer 1 ribonuclease III
multiple interactions
ISO
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of DICER1 mRNA
CTD
PMID:35861251
NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965
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Dlg4
discs large MAGUK scaffold protein 4
multiple interactions increases expression
ISO
Gabapentin inhibits the reaction [monobutyl phthalate results in increased expression of DLG4 protein] monobutyl phthalate results in increased expression of DLG4 mRNA; monobutyl phthalate results in increased expression of DLG4 protein
CTD
PMID:35278568
NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153
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Dmtn
dematin actin binding protein
decreases expression
ISO
monobutyl phthalate results in decreased expression of DMTN mRNA
CTD
PMID:35278568
NCBI chr15:45,677,974...45,702,261
Ensembl chr15:45,677,977...45,705,601
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Dnmt1
DNA methyltransferase 1
multiple interactions
ISO
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] affects the expression of DNMT1 mRNA; [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of DNMT1 mRNA
CTD
PMID:35861251
NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
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Dnmt3a
DNA methyltransferase 3 alpha
decreases expression
ISO
monobutyl phthalate results in decreased expression of DNMT3A protein
CTD
PMID:26745512
NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687
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Dnmt3b
DNA methyltransferase 3 beta
decreases expression
ISO
monobutyl phthalate results in decreased expression of DNMT3B protein
CTD
PMID:26745512
NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124
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Dpep3
dipeptidase 3
increases expression
EXP
monobutyl phthalate results in increased expression of DPEP3 mRNA
CTD
PMID:29162477
NCBI chr19:33,868,229...33,876,609
Ensembl chr19:33,868,242...33,873,896
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Drc12
dynein regulatory complex subunit 12 homolog
increases expression
EXP
monobutyl phthalate results in increased expression of CCDC153 mRNA
CTD
PMID:29162477
NCBI chr 8:44,576,528...44,584,345
Ensembl chr 8:44,577,836...44,584,338
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Drosha
drosha ribonuclease III
multiple interactions
ISO
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of DROSHA mRNA
CTD
PMID:35861251
NCBI chr 2:61,864,886...61,976,688
Ensembl chr 2:61,864,970...61,976,688
G
Dtx4
deltex E3 ubiquitin ligase 4
decreases expression
EXP
monobutyl phthalate results in decreased expression of DTX4 mRNA
CTD
PMID:20864626
NCBI chr 1:209,457,719...209,545,163
Ensembl chr 1:209,460,735...209,492,818
G
Dusp1
dual specificity phosphatase 1
multiple interactions
ISO
[monobutyl phthalate co-treated with Dexamethasone] results in increased expression of DUSP1 mRNA
CTD
PMID:34273429
NCBI chr10:16,680,478...16,683,275
G
Dynlrb2
dynein light chain roadblock-type 2
increases expression
EXP
monobutyl phthalate results in increased expression of DYNLRB2 mRNA
CTD
PMID:29162477
NCBI chr19:44,520,134...44,531,384
Ensembl chr19:44,520,134...44,531,387
G
Ebpl
EBP like
decreases expression
EXP
monobutyl phthalate results in decreased expression of EBPL mRNA
CTD
PMID:20864626
NCBI chr15:35,508,074...35,531,472
Ensembl chr15:35,508,074...35,531,472
G
Eci1
enoyl-CoA delta isomerase 1
decreases expression
EXP
monobutyl phthalate results in decreased expression of ECI1 mRNA
CTD
PMID:20864626
NCBI chr10:13,456,715...13,470,061
Ensembl chr10:13,456,563...13,470,061
G
Eef1b2
eukaryotic translation elongation factor 1 beta 2
decreases expression
ISO
monobutyl phthalate results in decreased expression of EEF1B2 protein
CTD
PMID:20553848
NCBI chr 9:64,580,163...64,582,737
Ensembl chr 9:64,579,893...64,582,737
G
Efcab10
EF-hand calcium binding domain 10
affects expression
ISO
monobutyl phthalate affects the expression of EFCAB10 mRNA
CTD
PMID:21195148
NCBI chr 6:50,004,479...50,011,398
Ensembl chr 6:50,004,479...50,011,398
G
Egr2
early growth response 2
affects expression
ISO
monobutyl phthalate affects the expression of EGR2 mRNA
CTD
PMID:19162170
NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562
G
Eif3b
eukaryotic translation initiation factor 3, subunit B
decreases expression
ISO
monobutyl phthalate results in decreased expression of EIF3B protein
CTD
PMID:20553848
NCBI chr12:14,196,403...14,220,865
Ensembl chr12:14,196,403...14,220,886
G
Elf3
E74 like ETS transcription factor 3
increases expression
EXP
monobutyl phthalate results in increased expression of ELF3 mRNA
CTD
PMID:29162477
NCBI chr13:46,690,460...46,695,394
Ensembl chr13:46,690,466...46,695,481
G
Elfn1
extracellular leucine-rich repeat and fibronectin type III domain containing 1
decreases expression
ISO
monobutyl phthalate results in decreased expression of ELFN1 mRNA
CTD
PMID:35278568
NCBI chr12:14,660,049...14,725,709
Ensembl chr12:14,660,083...14,724,580
G
Ell
elongation factor for RNA polymerase II
decreases expression
EXP
monobutyl phthalate results in decreased expression of ELL mRNA
CTD
PMID:20864626
NCBI chr16:18,843,775...18,891,484
Ensembl chr16:18,843,780...18,891,118
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Emc6
ER membrane protein complex subunit 6
decreases expression
EXP
monobutyl phthalate results in decreased expression of EMC6 mRNA
CTD
PMID:20864626
NCBI chr10:57,794,072...57,795,671
Ensembl chr10:57,793,685...57,796,217
G
Endod1
endonuclease domain containing 1
decreases expression
EXP
monobutyl phthalate results in decreased expression of ENDOD1 mRNA
CTD
PMID:20864626
NCBI chr 8:11,209,113...11,238,507
Ensembl chr 8:11,211,110...11,238,892
G
Enpp2
ectonucleotide pyrophosphatase/phosphodiesterase 2
affects expression
ISO
monobutyl phthalate affects the expression of ENPP2 mRNA
CTD
PMID:19162170
NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827
G
Eomes
eomesodermin
affects expression
ISO
monobutyl phthalate affects the expression of EOMES mRNA
CTD
PMID:19162170
NCBI chr 8:118,181,340...118,189,186
Ensembl chr 8:118,181,777...118,188,316
G
Epb41l1
erythrocyte membrane protein band 4.1-like 1
affects expression
ISO
monobutyl phthalate affects the expression of EPB41L1 mRNA
CTD
PMID:21195148
NCBI chr 3:144,929,195...145,052,723
Ensembl chr 3:144,984,640...145,052,721
G
Epb41l3
erythrocyte membrane protein band 4.1-like 3
affects expression
ISO
monobutyl phthalate affects the expression of EPB41L3 mRNA
CTD
PMID:20421339 PMID:21195148
NCBI chr 9:109,056,178...109,260,607
Ensembl chr 9:109,016,113...109,260,607
G
Epha1
Eph receptor A1
affects expression
ISO
monobutyl phthalate affects the expression of EPHA1 mRNA
CTD
PMID:19162170
NCBI chr 4:71,246,409...71,260,920
Ensembl chr 4:71,246,409...71,260,846
G
Ercc8
ERCC excision repair 8, CSA ubiquitin ligase complex subunit
affects expression
EXP
monobutyl phthalate affects the expression of ERCC8 mRNA
CTD
PMID:20864626
NCBI chr 2:39,647,393...39,686,229
Ensembl chr 2:39,647,452...39,684,859
G
Esr1
estrogen receptor 1
multiple interactions
ISO
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] affects the expression of ESR1 mRNA
CTD
PMID:35861251
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
G
Esyt2
extended synaptotagmin 2
decreases expression
EXP
monobutyl phthalate results in decreased expression of ESYT2 mRNA
CTD
PMID:20864626
NCBI chr 6:137,219,653...137,312,590
Ensembl chr 6:137,219,707...137,312,590
G
Etnk1
ethanolamine kinase 1
decreases expression
EXP
monobutyl phthalate results in decreased expression of ETNK1 mRNA
CTD
PMID:29162477
NCBI chr 4:176,126,056...176,170,325
Ensembl chr 4:176,126,180...176,193,770
G
Etv2
ETS variant transcription factor 2
increases expression
EXP
monobutyl phthalate results in increased expression of ETV2 mRNA
CTD
PMID:29162477
NCBI chr 1:85,890,562...85,894,025
Ensembl chr 1:85,890,559...85,893,431
G
Evx1
even-skipped homeobox 1
affects expression
ISO
monobutyl phthalate affects the expression of EVX1 mRNA
CTD
PMID:19162170
NCBI chr 4:81,416,590...81,420,967
Ensembl chr 4:81,416,590...81,420,967
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F3
coagulation factor III, tissue factor
affects expression
ISO
monobutyl phthalate affects the expression of F3 mRNA
CTD
PMID:19162170
NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
G
Fabp4
fatty acid binding protein 4
increases expression multiple interactions
ISO
monobutyl phthalate results in increased expression of FABP4 mRNA T 0070907 inhibits the reaction [monobutyl phthalate results in increased expression of FABP4 mRNA]
CTD
PMID:35421560
NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578
G
Fabp6
fatty acid binding protein 6
increases expression
EXP
monobutyl phthalate results in increased expression of FABP6 mRNA
CTD
PMID:29162477
NCBI chr10:28,063,603...28,068,276
Ensembl chr10:28,063,603...28,068,282
G
Fam171a2
family with sequence similarity 171, member A2
decreases expression
EXP
monobutyl phthalate results in decreased expression of FAM171A2 mRNA
CTD
PMID:29162477
NCBI chr10:87,393,888...87,404,051
Ensembl chr10:87,394,007...87,404,053
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Fam204a
family with sequence similarity 204, member A
increases expression
EXP
monobutyl phthalate results in increased expression of FAM204A mRNA
CTD
PMID:29162477
NCBI chr 1:259,328,551...259,366,726
Ensembl chr 1:259,337,709...259,367,077
G
Fasn
fatty acid synthase
multiple interactions decreases expression
ISO
monobutyl phthalate inhibits the reaction [Dexamethasone results in increased expression of FASN mRNA] monobutyl phthalate results in decreased expression of FASN mRNA
CTD
PMID:34273429 PMID:36736749
NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
G
Fastkd3
FAST kinase domains 3
decreases expression
EXP
monobutyl phthalate results in decreased expression of FASTKD3 mRNA
CTD
PMID:20864626
NCBI chr 1:34,858,342...34,866,988
Ensembl chr 1:34,858,219...34,866,973
G
Fbl
fibrillarin
decreases expression
ISO
monobutyl phthalate results in decreased expression of FBL protein
CTD
PMID:20553848
NCBI chr 1:83,469,832...83,478,932
Ensembl chr 1:83,469,832...83,478,932
G
Fbln2
fibulin 2
increases expression
EXP
monobutyl phthalate results in increased expression of FBLN2 mRNA
CTD
PMID:20864626
NCBI chr 4:123,704,289...123,763,857
Ensembl chr 4:123,704,373...123,763,948
G
Fbrs
fibrosin
increases expression
EXP
monobutyl phthalate results in increased expression of FBRS mRNA
CTD
PMID:20864626
NCBI chr 1:182,090,741...182,104,026
Ensembl chr 1:182,089,844...182,103,828
G
Fbxo16
F-box protein 16
increases expression
EXP
monobutyl phthalate results in increased expression of FBXO16 mRNA
CTD
PMID:29162477
NCBI chr15:39,492,268...39,541,493
Ensembl chr15:39,492,377...39,541,480
G
Fcsk
fucose kinase
increases expression
EXP
monobutyl phthalate results in increased expression of FCSK mRNA
CTD
PMID:20864626
NCBI chr19:38,849,130...38,874,497
Ensembl chr19:38,854,762...38,874,418
G
Fdps
farnesyl diphosphate synthase
decreases expression
ISO
monobutyl phthalate results in decreased expression of FDPS mRNA
CTD
PMID:35278568
NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776
G
Fdx1
ferredoxin 1
decreases expression
EXP
monobutyl phthalate results in decreased expression of FDX1 mRNA
CTD
PMID:20864626
NCBI chr 8:52,268,536...52,287,344
Ensembl chr 8:52,268,536...52,287,414
G
Fgf8
fibroblast growth factor 8
affects expression
ISO
monobutyl phthalate affects the expression of FGF8 mRNA
CTD
PMID:19162170
NCBI chr 1:244,584,477...244,590,578
Ensembl chr 1:244,584,652...244,590,359
G
Fhl1
four and a half LIM domains 1
increases expression
EXP
monobutyl phthalate results in increased expression of FHL1 mRNA
CTD
PMID:20864626
NCBI chr X:134,555,399...134,614,930
Ensembl chr X:134,555,479...134,614,928
G
Fignl2
fidgetin-like 2
increases expression
EXP
monobutyl phthalate results in increased expression of FIGNL2 mRNA
CTD
PMID:29162477
NCBI chr 7:132,160,006...132,187,896
Ensembl chr 7:132,162,390...132,164,336
G
Filip1l
filamin A interacting protein 1-like
increases expression
EXP
monobutyl phthalate results in increased expression of FILIP1L mRNA
CTD
PMID:20864626
NCBI chr11:42,937,353...43,177,085
Ensembl chr11:42,940,467...43,177,415
G
Flg
filaggrin
multiple interactions
ISO
[FLG gene polymorphism affects the susceptibility to Dibutyl Phthalate] which affects the abundance of monobutyl phthalate
CTD
PMID:24380925
NCBI chr 2:178,884,793...178,912,986
G
Flnc
filamin C
decreases expression
ISO
monobutyl phthalate results in decreased expression of FLNC mRNA
CTD
PMID:35278568
NCBI chr 4:58,034,088...58,061,882
Ensembl chr 4:58,034,189...58,061,844
G
Fmr1nb
FMR1 neighbor
decreases expression
EXP
monobutyl phthalate results in decreased expression of FMR1NB mRNA
CTD
PMID:29162477
NCBI chr X:147,309,613...147,332,426
Ensembl chr X:147,309,663...147,332,418
G
Fndc1
fibronectin type III domain containing 1
decreases expression
ISO
monobutyl phthalate results in decreased expression of FNDC1 mRNA
CTD
PMID:35278568
NCBI chr 1:47,281,839...47,364,247
Ensembl chr 1:47,281,844...47,364,259
G
Foxa1
forkhead box A1
affects expression
ISO
monobutyl phthalate affects the expression of FOXA1 mRNA
CTD
PMID:21195148
NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188
G
Foxd4
forkhead box D4
affects expression
ISO
monobutyl phthalate affects the expression of FOXD4 mRNA
CTD
PMID:21195148
NCBI chr 1:222,557,494...222,559,189
Ensembl chr 1:222,557,360...222,559,159
G
Foxj1
forkhead box J1
affects expression
ISO
monobutyl phthalate affects the expression of FOXJ1 mRNA
CTD
PMID:21195148
NCBI chr10:101,566,299...101,570,370
Ensembl chr10:101,566,304...101,570,237
G
Frzb
frizzled-related protein
affects expression
ISO
monobutyl phthalate affects the expression of FRZB mRNA
CTD
PMID:19162170
NCBI chr 3:65,332,274...65,365,208
Ensembl chr 3:65,332,277...65,365,208
G
Fst
follistatin
affects expression
ISO
monobutyl phthalate affects the expression of FST mRNA
CTD
PMID:19162170
NCBI chr 2:46,123,260...46,130,584
Ensembl chr 2:46,123,439...46,130,571
G
Ftl1l7
ferritin light chain 1 like 7
increases expression
EXP
monobutyl phthalate results in increased expression of FTL1L7 mRNA
CTD
PMID:29162477
NCBI chr 1:165,377,580...165,378,490
Ensembl chr 1:165,377,553...165,378,489
G
Fxr1
FMR1 autosomal homolog 1
increases expression
EXP
monobutyl phthalate results in increased expression of FXR1 mRNA
CTD
PMID:29162477
NCBI chr 2:116,884,167...116,937,590
Ensembl chr 2:116,884,248...116,937,590
G
G6pc1
glucose-6-phosphatase catalytic subunit 1
multiple interactions
ISO
monobutyl phthalate inhibits the reaction [Dexamethasone results in increased expression of G6PC1 protein]
CTD
PMID:34273429
NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804
G
Gadd45a
growth arrest and DNA-damage-inducible, alpha
affects expression
EXP
monobutyl phthalate affects the expression of GADD45A mRNA
CTD
PMID:20864626
NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
G
Gak
cyclin G associated kinase
affects expression
EXP
monobutyl phthalate affects the expression of GAK mRNA
CTD
PMID:20864626
NCBI chr14:1,089,853...1,164,098
Ensembl chr14:1,089,866...1,216,398
G
Gas1
growth arrest-specific 1
affects expression
ISO
monobutyl phthalate affects the expression of GAS1 mRNA
CTD
PMID:19162170
NCBI chr17:4,482,168...4,485,153
G
Gdf10
growth differentiation factor 10
decreases expression
EXP
monobutyl phthalate results in decreased expression of GDF10 mRNA
CTD
PMID:20864626
NCBI chr16:9,237,182...9,250,537
Ensembl chr16:9,237,261...9,249,343
G
Gdf3
growth differentiation factor 3
increases expression
EXP
monobutyl phthalate results in increased expression of GDF3 mRNA
CTD
PMID:29162477
NCBI chr 4:155,831,572...155,835,953
Ensembl chr 4:155,830,909...155,835,937
G
Gfap
glial fibrillary acidic protein
multiple interactions increases expression
ISO
LMT-28 inhibits the reaction [monobutyl phthalate results in increased expression of GFAP protein]; monobutyl phthalate promotes the reaction [[STAT3 protein binds to GFAP promoter] which results in increased expression of GFAP protein]
CTD
PMID:35278568
NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
G
Gipc2
GIPC PDZ domain containing family, member 2
decreases expression
ISO
monobutyl phthalate results in decreased expression of GIPC2 mRNA
CTD
PMID:35278568
NCBI chr 2:241,030,764...241,110,236
Ensembl chr 2:241,030,770...241,110,236
G
Gjb4
gap junction protein, beta 4
decreases expression
EXP
monobutyl phthalate results in decreased expression of GJB4 mRNA
CTD
PMID:29162477
NCBI chr 5:139,675,776...139,679,551
Ensembl chr 5:139,675,780...139,679,667
G
Gkn3
gastrokine 3
decreases expression
EXP
monobutyl phthalate results in decreased expression of GKN3 mRNA
CTD
PMID:29162477
NCBI chr 4:119,828,859...119,833,924
Ensembl chr 4:119,829,005...119,834,842
G
Gosr1
golgi SNAP receptor complex member 1
decreases expression
EXP
monobutyl phthalate results in decreased expression of GOSR1 mRNA
CTD
PMID:20864626
NCBI chr10:61,570,499...61,607,287
Ensembl chr10:61,450,494...61,607,177 Ensembl chr10:61,450,494...61,607,177
G
Gpat3
glycerol-3-phosphate acyltransferase 3
increases expression
ISO
monobutyl phthalate results in increased expression of GPAT3 mRNA
CTD
PMID:36736749
NCBI chr14:8,715,367...8,768,051
Ensembl chr14:8,714,373...8,766,490
G
Gprin2
G protein regulated inducer of neurite outgrowth 2
increases expression
EXP
monobutyl phthalate results in increased expression of GPRIN2 mRNA
CTD
PMID:29162477
NCBI chr16:9,496,452...9,512,672
Ensembl chr16:9,505,643...9,507,010
G
Gpx4
glutathione peroxidase 4
decreases expression multiple interactions
ISO
monobutyl phthalate results in decreased expression of GPX4 protein angoline inhibits the reaction [monobutyl phthalate results in decreased expression of GPX4 protein]; ferrostatin-1 inhibits the reaction [monobutyl phthalate results in decreased expression of GPX4 protein]
CTD
PMID:37121744
NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
G
Grb14
growth factor receptor bound protein 14
increases expression decreases expression
EXP ISO
monobutyl phthalate results in increased expression of GRB14 mRNA monobutyl phthalate results in decreased expression of GRB14 mRNA
CTD
PMID:29162477 PMID:35278568
NCBI chr 3:49,568,210...49,683,805
Ensembl chr 3:49,568,210...49,683,889
G
Grpr
gastrin releasing peptide receptor
decreases expression
EXP
monobutyl phthalate results in decreased expression of GRPR mRNA
CTD
PMID:20864626
NCBI chr X:30,998,425...31,038,442
Ensembl chr X:30,998,416...31,038,442
G
Grwd1
glutamate-rich WD repeat containing 1
decreases expression
EXP
monobutyl phthalate results in decreased expression of GRWD1 mRNA
CTD
PMID:20864626
NCBI chr 1:96,301,260...96,306,962
Ensembl chr 1:96,301,261...96,307,201
G
Gsc
goosecoid homeobox
affects expression
ISO
monobutyl phthalate affects the expression of GSC mRNA
CTD
PMID:19162170
NCBI chr 6:123,388,072...123,390,111
Ensembl chr 6:123,388,072...123,390,111
G
Guca2a
guanylate cyclase activator 2A
increases expression
EXP
monobutyl phthalate results in increased expression of GUCA2A mRNA
CTD
PMID:29162477
NCBI chr 5:133,237,177...133,239,019
Ensembl chr 5:133,237,177...133,239,018
G
H1f0
H1.0 linker histone
affects expression
ISO
monobutyl phthalate affects the expression of H1F0 mRNA
CTD
PMID:20421339
NCBI chr 7:110,592,834...110,594,694
Ensembl chr 7:110,592,208...110,594,694
G
H2-Q7-ps1
histocompatibility 2, Q region locus 7 like, pseudogene 1
decreases expression
EXP
monobutyl phthalate results in decreased expression of H2-Q7-PS1 mRNA
CTD
PMID:29162477
NCBI chr20:2,632,898...2,635,694
G
H2ac4
H2A clustered histone 4
decreases expression
ISO
monobutyl phthalate results in decreased expression of H2AC4 mRNA
CTD
PMID:35278568
NCBI chr17:42,799,884...42,800,387
Ensembl chr17:42,799,652...42,800,381
G
H2bc1
H2B clustered histone 1
increases expression
ISO
monobutyl phthalate results in increased expression of H2BC1 protein
CTD
PMID:20553848
NCBI chr17:41,172,041...41,172,510
Ensembl chr17:41,171,903...41,176,782 Ensembl chr17:41,171,903...41,176,782
G
Hacd1
3-hydroxyacyl-CoA dehydratase 1
decreases expression
EXP
monobutyl phthalate results in decreased expression of HACD1 mRNA
CTD
PMID:20864626
NCBI chr17:77,081,508...77,106,114
Ensembl chr17:77,083,740...77,106,073
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Has2
hyaluronan synthase 2
affects expression
ISO
monobutyl phthalate affects the expression of HAS2 mRNA
CTD
PMID:21195148
NCBI chr 7:88,113,326...88,139,337
Ensembl chr 7:88,113,326...88,128,933
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Hba-a3
hemoglobin alpha, adult chain 3
increases expression
EXP
monobutyl phthalate results in increased expression of HBA2 mRNA
CTD
PMID:29162477
NCBI chr10:15,311,637...15,312,481
Ensembl chr10:15,311,634...15,312,481
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Heca
hdc homolog, cell cycle regulator
increases expression
EXP
monobutyl phthalate results in increased expression of HECA mRNA
CTD
PMID:20864626
NCBI chr 1:12,525,445...12,575,358
Ensembl chr 1:12,525,135...12,576,427
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Hes7
hes family bHLH transcription factor 7
increases expression
EXP
monobutyl phthalate results in increased expression of HES7 mRNA
CTD
PMID:29162477
NCBI chr10:53,824,124...53,828,934
Ensembl chr10:53,825,574...53,828,097
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Hgd
homogentisate 1, 2-dioxygenase
increases expression
EXP
monobutyl phthalate results in increased expression of HGD mRNA
CTD
PMID:29162477
NCBI chr11:63,086,750...63,138,325
Ensembl chr11:63,086,752...63,138,323
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Hipk2
homeodomain interacting protein kinase 2
affects expression
EXP
monobutyl phthalate affects the expression of HIPK2 mRNA
CTD
PMID:20864626
NCBI chr 4:67,439,327...67,619,223
Ensembl chr 4:67,440,501...67,619,223
G
Hist2h2be
histone cluster 2 H2B family member E
increases expression
EXP
monobutyl phthalate results in increased expression of HIST2H2BE mRNA
CTD
PMID:29162477
NCBI chr 2:183,780,583...183,783,030
G
Hlcs
holocarboxylase synthetase
increases expression
EXP
monobutyl phthalate results in increased expression of HLCS mRNA
CTD
PMID:29162477
NCBI chr11:33,455,806...33,635,197
Ensembl chr11:33,455,809...33,624,222
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Hmga2
high mobility group AT-hook 2
affects expression
ISO
monobutyl phthalate affects the expression of HMGA2 mRNA
CTD
PMID:19162170
NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784
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Hmgb2
high mobility group box 2
decreases expression
ISO
monobutyl phthalate results in decreased expression of HMGB2 protein
CTD
PMID:20553848
NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140
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Hmgb4l9
high-mobility group box 4 like 9
increases expression
EXP
monobutyl phthalate results in increased expression of HMGB4L9 mRNA
CTD
PMID:29162477
NCBI chr X:134,184,390...134,185,772
Ensembl chr X:134,184,560...134,185,264
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Hmx3
H6 family homeobox 3
decreases expression
ISO
monobutyl phthalate results in decreased expression of HMX3 mRNA
CTD
PMID:35278568
NCBI chr 1:186,313,237...186,315,201
Ensembl chr 1:186,313,063...186,315,201
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Hnrnph2
heterogeneous nuclear ribonucleoprotein H2
increases expression
ISO
monobutyl phthalate results in increased expression of HNRNPH2 protein
CTD
PMID:20553848
NCBI chr X:97,780,890...97,786,846
Ensembl chr X:97,780,785...97,787,041
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Hoxa11
homeobox A11
decreases expression
EXP
monobutyl phthalate results in decreased expression of HOXA11 mRNA
CTD
PMID:29162477
NCBI chr 4:81,342,527...81,346,189
Ensembl chr 4:81,342,528...81,346,232
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Hoxa6
homeobox A6
increases expression
EXP
monobutyl phthalate results in increased expression of HOXA6 mRNA
CTD
PMID:29162477
NCBI chr 4:81,304,918...81,313,184
Ensembl chr 4:81,306,407...81,308,850
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Hoxc12
homeo box C12
decreases expression
EXP
monobutyl phthalate results in decreased expression of HOXC12 mRNA
CTD
PMID:29162477
NCBI chr 7:134,074,199...134,075,797
Ensembl chr 7:134,074,199...134,075,797
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Hpdl
4-hydroxyphenylpyruvate dioxygenase-like
decreases expression
ISO
monobutyl phthalate results in decreased expression of HPDL mRNA
CTD
PMID:35278568
NCBI chr 5:130,286,627...130,288,233
Ensembl chr 5:130,286,631...130,288,233
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Hps6
HPS6, biogenesis of lysosomal organelles complex 2 subunit 3
increases expression
EXP
monobutyl phthalate results in increased expression of HPS6 mRNA
CTD
PMID:29162477
NCBI chr 1:244,853,256...244,855,865
Ensembl chr 1:244,853,194...244,855,883
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Hsd11b2
hydroxysteroid 11-beta dehydrogenase 2
affects expression
ISO
monobutyl phthalate affects the expression of HSD11B2 mRNA
CTD
PMID:21195148
NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899
G
Hsd17b1
hydroxysteroid (17-beta) dehydrogenase 1
affects expression
ISO
monobutyl phthalate affects the expression of HSD17B1 mRNA
CTD
PMID:28381288
NCBI chr10:86,009,728...86,011,928
Ensembl chr10:86,009,728...86,011,927
G
Hsd3b1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
increases expression
ISO
monobutyl phthalate results in increased expression of HSD3B1 mRNA
CTD
PMID:34280466
NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999
G
Hspa5
heat shock protein family A (Hsp70) member 5
increases expression
ISO
monobutyl phthalate results in increased expression of HSPA5 protein
CTD
PMID:20553848
NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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Hspb1
heat shock protein family B (small) member 1
increases expression
ISO EXP
monobutyl phthalate results in increased expression of HSPB1 protein monobutyl phthalate results in increased expression of HSPB1 mRNA
CTD
PMID:20553848 PMID:20864626
NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
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Hspb6
heat shock protein family B (small) member 6
increases expression
EXP
monobutyl phthalate results in increased expression of HSPB6 mRNA
CTD
PMID:20864626
NCBI chr 1:85,806,898...85,809,072
Ensembl chr 1:85,806,146...85,809,071
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Hyal3
hyaluronidase 3
increases expression
ISO
monobutyl phthalate results in increased expression of HYAL3 mRNA
CTD
PMID:35278568
NCBI chr 8:108,254,385...108,260,020
Ensembl chr 8:108,250,667...108,260,647
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Id3
inhibitor of DNA binding 3
increases expression
EXP
monobutyl phthalate results in increased expression of ID3 mRNA
CTD
PMID:20864626
NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349
G
Ier5l
immediate early response 5-like
decreases expression
ISO
monobutyl phthalate results in decreased expression of IER5L mRNA
CTD
PMID:35278568
NCBI chr 3:13,744,056...13,745,647
Ensembl chr 3:13,744,078...13,745,647
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Igfbp3
insulin-like growth factor binding protein 3
affects expression
ISO
monobutyl phthalate affects the expression of IGFBP3 mRNA
CTD
PMID:19162170
NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083
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Ihh
Indian hedgehog signaling molecule
increases expression
EXP
monobutyl phthalate results in increased expression of IHH mRNA
CTD
PMID:29162477
NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532
G
Ikbkb
inhibitor of nuclear factor kappa B kinase subunit beta
increases expression increases phosphorylation
EXP ISO
monobutyl phthalate results in increased expression of IKBKB mRNA monobutyl phthalate results in increased phosphorylation of IKBKB protein
CTD
PMID:20864626 PMID:26745512
NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
G
Il10
interleukin 10
increases expression decreases expression
ISO
monobutyl phthalate results in increased expression of IL10 mRNA monobutyl phthalate results in decreased expression of IL10 protein
CTD
PMID:32015430 PMID:35584204
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
G
Il10rb
interleukin 10 receptor subunit beta
increases expression
EXP
monobutyl phthalate results in increased expression of IL10RB mRNA
CTD
PMID:20864626
NCBI chr11:30,646,494...30,668,081
Ensembl chr11:30,652,096...30,668,074
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Il18
interleukin 18
affects expression
ISO
monobutyl phthalate affects the expression of IL18 mRNA
CTD
PMID:20421339
NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
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Il1b
interleukin 1 beta
increases expression
ISO
monobutyl phthalate results in increased expression of IL1B mRNA
CTD
PMID:32015430
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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Il4
interleukin 4
increases expression
ISO
monobutyl phthalate results in increased expression of IL4 mRNA
CTD
PMID:12423647
NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
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Il4r
interleukin 4 receptor
increases expression
EXP
monobutyl phthalate results in increased expression of IL4RA mRNA
CTD
PMID:20864626
NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980
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Il6
interleukin 6
multiple interactions increases expression increases phosphorylation
ISO
[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-benzyl phthalate co-treated with monobutyl phthalate] results in increased expression of IL6 mRNA monobutyl phthalate results in increased expression of IL6 mRNA angoline inhibits the reaction [monobutyl phthalate results in increased expression of IL6 mRNA] monobutyl phthalate results in increased phosphorylation of IL6 protein
CTD
PMID:30398665 PMID:32015430 PMID:35278568 PMID:37121744
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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Ino80b
INO80 complex subunit B
decreases expression
ISO
monobutyl phthalate results in decreased expression of INO80B mRNA
CTD
PMID:35278568
NCBI chr 4:115,627,907...115,631,069
Ensembl chr 4:115,627,908...115,631,456
G
Ino80c
INO80 complex subunit C
decreases expression
EXP
monobutyl phthalate results in decreased expression of INO80C mRNA
CTD
PMID:20864626
NCBI chr18:15,378,764...15,398,574
Ensembl chr18:15,378,770...15,393,403
G
Insl3
insulin-like 3
decreases expression
EXP
monobutyl phthalate results in decreased expression of INSL3 mRNA
CTD
PMID:16338306
NCBI chr16:18,398,682...18,400,566
Ensembl chr16:18,384,829...18,400,560
G
Iqcf1
IQ motif containing F1
increases expression
EXP
monobutyl phthalate results in increased expression of IQCF1 mRNA
CTD
PMID:29162477
NCBI chr 8:107,129,462...107,133,242
Ensembl chr 8:107,130,704...107,133,249
G
Irak1
interleukin-1 receptor-associated kinase 1
affects expression increases ubiquitination increases expression
ISO
monobutyl phthalate affects the expression of IRAK1 mRNA monobutyl phthalate results in increased ubiquitination of IRAK1 protein monobutyl phthalate results in increased expression of IRAK1 protein
CTD
PMID:32738922
NCBI chr X:151,768,621...151,778,521
Ensembl chr X:151,768,777...151,778,521
G
Irx3
iroquois homeobox 3
affects expression increases expression
ISO EXP
monobutyl phthalate affects the expression of IRX3 mRNA monobutyl phthalate results in increased expression of IRX3 mRNA
CTD
PMID:21195148 PMID:29162477
NCBI chr19:15,211,882...15,215,317
Ensembl chr19:15,211,878...15,215,317
G
Irx5
iroquois homeobox 5
affects expression
ISO
monobutyl phthalate affects the expression of IRX5 mRNA
CTD
PMID:21195148
NCBI chr19:14,639,052...14,643,911
Ensembl chr19:14,624,225...14,642,318
G
Jak2
Janus kinase 2
increases phosphorylation multiple interactions
ISO
monobutyl phthalate results in increased phosphorylation of JAK2 protein alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [monobutyl phthalate results in increased phosphorylation of JAK2 protein]
CTD
PMID:35278568
NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
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Jun
Jun proto-oncogene, AP-1 transcription factor subunit
multiple interactions
ISO
monobutyl phthalate results in increased phosphorylation of and affects the localization of JUN protein; pyrazolanthrone inhibits the reaction [monobutyl phthalate results in increased phosphorylation of JUN protein]
CTD
PMID:32738922
NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
G
Kctd14
potassium channel tetramerization domain containing 14
decreases expression
EXP
monobutyl phthalate results in decreased expression of KCTD14 mRNA
CTD
PMID:20864626
NCBI chr 1:151,761,688...151,766,693
Ensembl chr 1:151,761,663...151,766,691
G
Kdm4b
lysine demethylase 4B
affects expression
ISO
monobutyl phthalate affects the expression of KDM4B mRNA
CTD
PMID:20421339
NCBI chr 9:1,158,737...1,237,233
Ensembl chr 9:1,158,752...1,236,543
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Kidins220
kinase D-interacting substrate 220
increases expression
EXP
monobutyl phthalate results in increased expression of KIDINS220 mRNA
CTD
PMID:20864626
NCBI chr 6:41,618,207...41,706,990
Ensembl chr 6:41,618,294...41,703,256
G
Kif27
kinesin family member 27
affects expression
ISO
monobutyl phthalate affects the expression of KIF27 mRNA
CTD
PMID:21195148
NCBI chr17:6,299,544...6,375,106
Ensembl chr17:6,299,569...6,369,768
G
Klf10
KLF transcription factor 10
affects expression
ISO
monobutyl phthalate affects the expression of KLF10 mRNA
CTD
PMID:21195148
NCBI chr 7:69,467,658...69,473,726
Ensembl chr 7:69,465,619...69,473,994
G
Klf11
KLF transcription factor 11
affects expression
ISO
monobutyl phthalate affects the expression of KLF11 mRNA
CTD
PMID:21195148
NCBI chr 6:41,285,699...41,297,548
Ensembl chr 6:41,285,842...41,297,550
G
Klk1c3
kallikrein 1-related peptidase C3
increases expression
EXP
monobutyl phthalate results in increased expression of KLK1C3 mRNA
CTD
PMID:29162477
NCBI chr 1:94,671,636...94,675,417
Ensembl chr 1:94,671,618...94,675,417
G
Klk8
kallikrein related-peptidase 8
decreases expression
ISO
monobutyl phthalate results in decreased expression of KLK8 mRNA
CTD
PMID:35278568
NCBI chr 1:94,251,803...94,258,646
Ensembl chr 1:94,251,803...94,258,646
G
Krt19
keratin 19
increases expression
ISO
monobutyl phthalate results in increased expression of KRT19 protein
CTD
PMID:20553848
NCBI chr10:85,075,835...85,080,552
Ensembl chr10:85,066,802...85,171,799
G
Krt73
keratin 73
increases expression
ISO
monobutyl phthalate results in increased expression of KRT73 protein
CTD
PMID:20553848
NCBI chr 7:132,927,812...132,936,323
Ensembl chr 7:132,928,256...132,936,280
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Krt76
keratin 76
decreases expression
ISO
monobutyl phthalate results in decreased expression of KRT76 protein
CTD
PMID:20553848
NCBI chr 7:133,016,990...133,025,475
Ensembl chr 7:133,016,992...133,025,496
G
Krt8
keratin 8
affects expression
ISO
monobutyl phthalate affects the expression of KRT8 mRNA
CTD
PMID:19162170
NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
G
Krt87
keratin 87
increases expression
EXP
monobutyl phthalate results in increased expression of KRT83 mRNA
CTD
PMID:29162477
NCBI chr 7:132,547,388...132,555,005
Ensembl chr 7:132,548,141...132,554,978
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Lamc3
laminin subunit gamma 3
decreases expression
ISO
monobutyl phthalate results in decreased expression of LAMC3 mRNA
CTD
PMID:35278568
NCBI chr 3:15,165,220...15,226,697
Ensembl chr 3:15,165,220...15,226,697
G
Lats1
large tumor suppressor kinase 1
affects expression
EXP
monobutyl phthalate affects the expression of LATS1 mRNA
CTD
PMID:20864626
NCBI chr 1:2,160,411...2,193,640
Ensembl chr 1:2,160,411...2,193,640
G
Lbh
LBH regulator of WNT signaling pathway
affects expression
ISO
monobutyl phthalate affects the expression of LBH mRNA
CTD
PMID:21195148
NCBI chr 6:22,569,238...22,593,056
Ensembl chr 6:22,568,834...22,593,079
G
Ldha
lactate dehydrogenase A
increases expression
ISO
monobutyl phthalate results in increased expression of LDHA protein
CTD
PMID:36736749
NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472
G
Ldhb
lactate dehydrogenase B
increases expression
ISO
monobutyl phthalate results in increased expression of LDHB protein
CTD
PMID:20553848
NCBI chr 4:175,428,382...175,446,403
Ensembl chr 4:175,428,385...175,446,403
G
Lep
leptin
decreases secretion
ISO
monobutyl phthalate results in decreased secretion of LEP protein
CTD
PMID:29223775
NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
G
Lgr4
leucine-rich repeat-containing G protein-coupled receptor 4
affects expression
ISO
monobutyl phthalate affects the expression of LGR4 mRNA
CTD
PMID:20421339
NCBI chr 3:96,447,385...96,550,006
Ensembl chr 3:96,447,858...96,548,899
G
Lgr5
leucine rich repeat containing G protein coupled receptor 5
affects expression
ISO
monobutyl phthalate affects the expression of LGR5 mRNA
CTD
PMID:21195148
NCBI chr 7:51,087,059...51,221,882
Ensembl chr 7:51,088,239...51,222,446
G
Lhb
luteinizing hormone subunit beta
multiple interactions
ISO
[monobutyl phthalate co-treated with CGB3 protein] results in increased secretion of Progesterone; monobutyl phthalate promotes the reaction [CGB3 protein results in increased secretion of Progesterone]; RELA affects the reaction [[monobutyl phthalate co-treated with CGB3 protein] results in increased secretion of Progesterone]; VIM affects the reaction [[monobutyl phthalate co-treated with CGB3 protein] results in increased secretion of Progesterone]; VIM inhibits the reaction [RELA affects the reaction [[monobutyl phthalate co-treated with CGB3 protein] results in increased secretion of Progesterone]]
CTD
PMID:26745512
NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972 Ensembl chr 1:95,900,984...95,901,972
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Lhpp
phospholysine phosphohistidine inorganic pyrophosphate phosphatase
affects expression
ISO
monobutyl phthalate affects the expression of LHPP mRNA
CTD
PMID:21195148
NCBI chr 1:187,403,390...187,494,577
Ensembl chr 1:187,403,433...187,494,578
G
Lhx2
LIM homeobox 2
increases expression
EXP
monobutyl phthalate results in increased expression of LHX2 mRNA
CTD
PMID:29162477
NCBI chr 3:22,113,619...22,143,909
Ensembl chr 3:22,126,007...22,143,908
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LOC120103107
PRAME family member 12-like
increases expression
EXP
monobutyl phthalate results in increased expression of ZFP27 mRNA
CTD
PMID:29162477
NCBI chr 5:156,009,794...156,012,390
Ensembl chr 5:156,009,836...156,012,357
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Loricrin
loricrin cornified envelope precursor protein
increases expression
EXP
monobutyl phthalate results in increased expression of LORICRIN mRNA
CTD
PMID:29162477
NCBI chr 2:177,558,062...177,560,960
Ensembl chr 2:177,558,252...177,559,807
G
Loxl3
lysyl oxidase-like 3
multiple interactions
ISO
[Phthalic Acids results in increased abundance of monobutyl phthalate] which results in decreased methylation of LOXL3 gene
CTD
PMID:37741207
NCBI chr 4:115,540,640...115,556,958
Ensembl chr 4:115,540,685...115,557,466
G
Lpl
lipoprotein lipase
multiple interactions
ISO
[Dibutyl Phthalate results in increased abundance of monobutyl phthalate] which affects the expression of LPL mRNA
CTD
PMID:34175954
NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
G
Lrig1
leucine-rich repeats and immunoglobulin-like domains 1
affects expression
ISO
monobutyl phthalate affects the expression of LRIG1 mRNA
CTD
PMID:21195148
NCBI chr 4:127,130,899...127,230,956
Ensembl chr 4:127,130,898...127,231,513
G
Lrrc4
leucine rich repeat containing 4
affects expression
ISO
monobutyl phthalate affects the expression of LRRC4 mRNA
CTD
PMID:21195148
NCBI chr 4:57,433,518...57,437,114
Ensembl chr 4:57,433,428...57,437,911
G
Lrrc56
leucine rich repeat containing 56
affects expression
ISO
monobutyl phthalate affects the expression of LRRC56 mRNA
CTD
PMID:21195148
NCBI chr 1:196,299,843...196,315,170
Ensembl chr 1:196,299,846...196,315,172
G
Lrrc71
leucine rich repeat containing 71
increases expression
EXP
monobutyl phthalate results in increased expression of LRRC71 mRNA
CTD
PMID:29162477
NCBI chr 2:173,194,792...173,207,448
Ensembl chr 2:173,194,792...173,207,448
G
Lysmd2
LysM domain containing 2
decreases expression
EXP
monobutyl phthalate results in decreased expression of LYSMD2 mRNA
CTD
PMID:20864626
NCBI chr 8:76,378,984...76,394,396
Ensembl chr 8:76,379,219...76,394,654
G
Lzts1
leucine zipper tumor suppressor 1
affects expression
EXP
monobutyl phthalate affects the expression of LZTS1 mRNA
CTD
PMID:20864626
NCBI chr16:20,542,756...20,598,204
Ensembl chr16:20,542,809...20,598,203
G
Mafa
MAF bZIP transcription factor A
increases expression decreases expression
ISO
monobutyl phthalate results in increased expression of MAFA protein monobutyl phthalate results in decreased expression of MAFA mRNA
CTD
PMID:35278568 PMID:38048874
NCBI chr 7:107,432,292...107,435,084
Ensembl chr 7:107,433,605...107,434,690
G
Maff
MAF bZIP transcription factor F
decreases expression
ISO
monobutyl phthalate results in decreased expression of MAFF mRNA
CTD
PMID:35278568
NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851
G
Mak
male germ cell-associated kinase
affects expression
ISO
monobutyl phthalate affects the expression of MAK mRNA
CTD
PMID:21195148
NCBI chr17:23,683,753...23,731,125
Ensembl chr17:23,693,878...23,730,001
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Manea
mannosidase, endo-alpha
affects expression
ISO
monobutyl phthalate affects the expression of MANEA mRNA
CTD
PMID:20421339
NCBI chr 5:40,196,373...40,218,540
Ensembl chr 5:40,196,396...40,218,459
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Map1lc3a
microtubule-associated protein 1 light chain 3 alpha
decreases expression
ISO
monobutyl phthalate results in decreased expression of MAP1LC3A mRNA
CTD
PMID:35278568
NCBI chr 3:143,783,024...143,784,670
Ensembl chr 3:143,783,024...143,784,670
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Mapk1
mitogen activated protein kinase 1
affects expression
EXP
monobutyl phthalate affects the expression of MAPK1 mRNA
CTD
PMID:20864626
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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Mapk15
mitogen-activated protein kinase 15
increases expression
EXP
monobutyl phthalate results in increased expression of MAPK15 mRNA
CTD
PMID:20864626
NCBI chr 7:107,694,907...107,714,640
Ensembl chr 7:107,694,964...107,714,645
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Marchf11
membrane associated ring-CH-type finger 11
decreases expression
EXP
monobutyl phthalate results in decreased expression of MARCHF11 mRNA
CTD
PMID:20864626
NCBI chr 2:76,898,330...76,999,690
Ensembl chr 2:76,898,386...76,999,691
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Mdh2
malate dehydrogenase 2
increases expression
ISO
monobutyl phthalate results in increased expression of MDH2 protein
CTD
PMID:20553848
NCBI chr12:20,894,269...20,907,225
Ensembl chr12:20,894,262...20,907,271
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Meak7
MTOR associated protein, eak-7 homolog
increases expression
EXP
monobutyl phthalate results in increased expression of MEAK7 mRNA
CTD
PMID:29162477
NCBI chr19:47,813,899...47,836,830
Ensembl chr19:47,811,416...47,841,278
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Mesp1
mesoderm posterior bHLH transcription factor 1
affects expression
ISO
monobutyl phthalate affects the expression of MESP1 mRNA
CTD
PMID:19162170
NCBI chr 1:133,738,357...133,739,875
Ensembl chr 1:133,738,357...133,739,875
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Mesp2
mesoderm posterior bHLH transcription factor 2
increases expression
EXP
monobutyl phthalate results in increased expression of MESP2 mRNA
CTD
PMID:29162477
NCBI chr 1:133,756,601...133,759,207
Ensembl chr 1:133,756,601...133,759,198
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Mex3d
mex-3 RNA binding family member D
decreases expression
EXP
monobutyl phthalate results in decreased expression of MEX3D mRNA
CTD
PMID:29162477
NCBI chr 7:9,325,575...9,332,705
Ensembl chr 7:9,325,488...9,332,096
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Mfsd4b2
major facilitator superfamily domain containing 4B2
increases expression
EXP
monobutyl phthalate results in increased expression of MFSD4B mRNA
CTD
PMID:29162477
NCBI chr20:43,344,601...43,353,061
Ensembl chr20:43,344,601...43,353,061
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Mgarp
mitochondria-localized glutamic acid-rich protein
decreases expression
ISO
monobutyl phthalate results in decreased expression of MGARP protein
CTD
PMID:36602389
NCBI chr 2:135,431,283...135,439,425
Ensembl chr 2:135,431,283...135,439,612
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Mir130a
microRNA 130a
decreases expression
ISO
monobutyl phthalate results in decreased expression of MIR130A mRNA
CTD
PMID:35278568
NCBI chr 3:69,822,542...69,822,629
Ensembl chr 3:69,822,542...69,822,629
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Mir141
microRNA 141
multiple interactions
ISO
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of MIR141 mRNA
CTD
PMID:35861251
NCBI chr 4:157,523,239...157,523,332
Ensembl chr 4:157,523,239...157,523,332
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Mir150
microRNA 150
increases expression
EXP
monobutyl phthalate results in increased expression of MIR150 mRNA
CTD
PMID:29162477
NCBI chr 1:95,605,024...95,605,108
Ensembl chr 1:95,605,024...95,605,108
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Mir154
microRNA 154
increases expression
EXP
monobutyl phthalate results in increased expression of MIR154 mRNA
CTD
PMID:29162477
NCBI chr 6:128,752,947...128,753,030
Ensembl chr 6:128,752,947...128,753,030
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Mir184
microRNA 184
multiple interactions
ISO
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] affects the expression of MIR184 mRNA
CTD
PMID:35861251
NCBI chr 8:90,343,134...90,343,210
Ensembl chr 8:90,343,134...90,343,210
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Mir199a2
microRNA 199a-2
increases expression
EXP
monobutyl phthalate results in increased expression of MIR199A2 mRNA
CTD
PMID:29162477
NCBI chr13:74,582,954...74,583,063
Ensembl chr13:74,582,954...74,583,063
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Mir222
microRNA 222
increases expression
ISO
monobutyl phthalate results in increased expression of MIR222 mRNA
CTD
PMID:35278568
NCBI chr X:3,428,904...3,429,006
Ensembl chr X:3,428,904...3,429,006
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Mir301b
microRNA 301b
increases expression
EXP
monobutyl phthalate results in increased expression of MIR301B mRNA
CTD
PMID:29162477
NCBI chr11:83,879,816...83,879,893
Ensembl chr11:83,879,816...83,879,893
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Mir328b
microRNA 328b
increases expression
EXP
monobutyl phthalate results in increased expression of MIR328B mRNA
CTD
PMID:29162477
NCBI chr14:43,663,068...43,663,185
Ensembl chr14:43,663,068...43,663,185
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Mir3584
microRNA 3584
increases expression
EXP
monobutyl phthalate results in increased expression of MIR3584 mRNA
CTD
PMID:29162477
NCBI chr 1:246,786,249...246,786,329
Ensembl chr 1:246,786,249...246,786,329
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Mir449a
microRNA 449a
increases expression
EXP
monobutyl phthalate results in increased expression of MIR449A mRNA
CTD
PMID:29162477
NCBI chr 2:44,670,714...44,670,804
Ensembl chr 2:44,670,714...44,670,804
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Mir93
microRNA 93
decreases expression
EXP
monobutyl phthalate results in decreased expression of MIR93 mRNA
CTD
PMID:29162477
NCBI chr12:17,043,135...17,043,221
Ensembl chr12:17,043,135...17,043,221
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Misp
mitotic spindle positioning
decreases expression
ISO
monobutyl phthalate results in decreased expression of MISP mRNA
CTD
PMID:35278568
NCBI chr 7:9,870,390...9,886,541
Ensembl chr 7:9,870,444...9,886,541
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Mixl1
Mix paired-like homeobox 1
affects expression
ISO
monobutyl phthalate affects the expression of MIXL1 mRNA
CTD
PMID:19162170
NCBI chr13:92,422,031...92,426,065
Ensembl chr13:92,422,031...92,426,065
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Mki67
marker of proliferation Ki-67
multiple interactions
ISO
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] affects the expression of MKI67 mRNA
CTD
PMID:35861251
NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
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Mlf1
myeloid leukemia factor 1
affects expression
ISO
monobutyl phthalate affects the expression of MLF1 mRNA
CTD
PMID:20421339
NCBI chr 2:151,648,492...151,681,654
Ensembl chr 2:151,648,511...151,681,652
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Mmp1
matrix metallopeptidase 1
increases expression
ISO
monobutyl phthalate results in increased expression of MMP1 protein
CTD
PMID:36113809
NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
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Mmp9
matrix metallopeptidase 9
multiple interactions
ISO
[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-benzyl phthalate co-treated with monobutyl phthalate] results in increased secretion of MMP9 protein
CTD
PMID:30398665
NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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Mogat1
monoacylglycerol O-acyltransferase 1
decreases expression
EXP
monobutyl phthalate results in decreased expression of MOGAT1 mRNA
CTD
PMID:20864626
NCBI chr 9:79,980,963...79,988,513
Ensembl chr 9:79,956,649...79,988,513
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Mrc1
mannose receptor, C type 1
multiple interactions
ISO
[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-benzyl phthalate co-treated with monobutyl phthalate] results in decreased expression of MRC1 mRNA
CTD
PMID:30398665
NCBI chr17:77,249,187...77,330,857
Ensembl chr17:77,249,187...77,330,857
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Mrm3
mitochondrial rRNA methyltransferase 3
decreases expression
EXP
monobutyl phthalate results in decreased expression of MRM3 mRNA
CTD
PMID:20864626
NCBI chr10:61,095,920...61,125,421
Ensembl chr10:61,095,952...61,102,630
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Mrpl19
mitochondrial ribosomal protein L19
decreases expression
EXP
monobutyl phthalate results in decreased expression of MRPL19 mRNA
CTD
PMID:20864626
NCBI chr 4:114,521,824...114,526,053
Ensembl chr 4:114,521,824...114,526,053
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Msr1
macrophage scavenger receptor 1
increases expression
EXP
monobutyl phthalate results in increased expression of MSR1 mRNA
CTD
PMID:29162477
NCBI chr16:52,717,775...52,803,602
Ensembl chr16:52,717,732...52,799,676
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Mt1
metallothionein 1
affects expression
ISO
monobutyl phthalate affects the expression of MT1 mRNA
CTD
PMID:21195148
NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049 Ensembl chr17:10,826,032...10,827,049
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Mt2A
metallothionein 2A
affects expression
ISO
monobutyl phthalate affects the expression of MT2 mRNA
CTD
PMID:21195148
NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
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Mthfd2l
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
decreases expression
EXP
monobutyl phthalate results in decreased expression of MTHFD2L mRNA
CTD
PMID:20864626
NCBI chr14:17,089,947...17,170,036
Ensembl chr14:17,089,952...17,170,112
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Mto1
mitochondrial tRNA translation optimization 1
decreases expression
EXP
monobutyl phthalate results in decreased expression of MTO1 mRNA
CTD
PMID:29162477
NCBI chr 8:79,309,681...79,335,231
Ensembl chr 8:79,309,982...79,335,231
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Mtrr
5-methyltetrahydrofolate-homocysteine methyltransferase reductase
decreases expression
EXP
monobutyl phthalate results in decreased expression of MTRR mRNA
CTD
PMID:20864626
NCBI chr 1:34,866,991...34,899,425
Ensembl chr 1:34,867,089...34,899,425
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Mutyh
mutY DNA glycosylase
increases expression
EXP
monobutyl phthalate results in increased expression of MUTYH mRNA
CTD
PMID:20864626
NCBI chr 5:130,274,034...130,286,149
Ensembl chr 5:130,274,122...130,286,146
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Mvd
mevalonate diphosphate decarboxylase
decreases expression
ISO
monobutyl phthalate results in decreased expression of MVD mRNA
CTD
PMID:35278568
NCBI chr19:50,496,366...50,506,429
Ensembl chr19:50,496,367...50,507,971
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Myh3
myosin heavy chain 3
decreases expression
ISO
monobutyl phthalate results in decreased expression of MYH3 mRNA
CTD
PMID:35278568
NCBI chr10:51,770,177...51,793,994
Ensembl chr10:51,770,177...51,793,992
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Myh6
myosin heavy chain 6
decreases expression
ISO
monobutyl phthalate results in decreased expression of MYH6 protein
CTD
PMID:20553848
NCBI chr15:28,418,120...28,442,316
Ensembl chr15:28,417,616...28,441,720
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Myh9
myosin, heavy chain 9
affects expression
EXP
monobutyl phthalate affects the expression of MYH9 mRNA
CTD
PMID:20864626
NCBI chr 7:109,343,718...109,424,457
Ensembl chr 7:109,343,706...109,424,457
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Myog
myogenin
decreases expression
ISO
monobutyl phthalate results in decreased expression of MYOG mRNA
CTD
PMID:35278568
NCBI chr13:45,745,455...45,748,044
Ensembl chr13:45,745,436...45,748,039
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Naaladl2
N-acetylated alpha-linked acidic dipeptidase-like 2
decreases expression
ISO
monobutyl phthalate results in decreased expression of NAALADL2 mRNA
CTD
PMID:35278568
NCBI chr 2:106,639,146...107,992,218
Ensembl chr 2:106,645,608...107,991,689
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Ndrg1
N-myc downstream regulated 1
affects expression
ISO
monobutyl phthalate affects the expression of NDRG1 mRNA
CTD
PMID:21195148
NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880
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Neil3
nei-like DNA glycosylase 3
decreases expression
EXP
monobutyl phthalate results in decreased expression of NEIL3 mRNA
CTD
PMID:29162477
NCBI chr16:38,359,305...38,418,528
Ensembl chr16:38,359,371...38,418,527
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Neurl3
neuralized E3 ubiquitin protein ligase 3
increases expression
EXP
monobutyl phthalate results in increased expression of NEURL3 mRNA
CTD
PMID:29162477
NCBI chr 9:38,494,486...38,503,352
Ensembl chr 9:38,494,489...38,502,649
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Nfe2l2
NFE2 like bZIP transcription factor 2
decreases expression
ISO
monobutyl phthalate results in decreased expression of NFE2L2 protein
CTD
PMID:30965081
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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Nfkbia
NFKB inhibitor alpha
increases phosphorylation
ISO
monobutyl phthalate results in increased phosphorylation of NFKBIA protein
CTD
PMID:26745512
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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Nfyb
nuclear transcription factor Y subunit beta
affects expression
ISO
monobutyl phthalate affects the expression of NFYB mRNA
CTD
PMID:20421339
NCBI chr 7:20,964,988...20,980,569
Ensembl chr 7:20,964,993...20,980,565
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Nkx2-8
NK2 homeobox 8
affects expression
ISO
monobutyl phthalate affects the expression of NKX2-9 mRNA
CTD
PMID:19162170
NCBI chr 6:74,086,274...74,087,977
Ensembl chr 6:74,086,274...74,087,977
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Nme5
NME/NM23 family member 5
affects expression
ISO
monobutyl phthalate affects the expression of NME5 mRNA
CTD
PMID:21195148
NCBI chr18:26,163,558...26,180,742
Ensembl chr18:26,163,555...26,180,794
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Nmur1
neuromedin U receptor 1
decreases expression
EXP
monobutyl phthalate results in decreased expression of NMUR1 mRNA
CTD
PMID:29162477
NCBI chr 9:87,033,231...87,038,070
Ensembl chr 9:87,033,279...87,036,684
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Nop58
NOP58 ribonucleoprotein
decreases expression
ISO
monobutyl phthalate results in decreased expression of NOL5 protein
CTD
PMID:20553848
NCBI chr 9:61,120,939...61,144,810
Ensembl chr 9:61,120,929...61,144,810
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Npm1
nucleophosmin 1
decreases expression
ISO
monobutyl phthalate results in decreased expression of NPM1 protein
CTD
PMID:20553848
NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645
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Nr1i2
nuclear receptor subfamily 1, group I, member 2
increases activity
EXP
monobutyl phthalate results in increased activity of NR1I2 protein
CTD
PMID:15901914
NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
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Nr3c1
nuclear receptor subfamily 3, group C, member 1
multiple interactions
ISO
monobutyl phthalate inhibits the reaction [Dexamethasone affects the localization of NR3C1 protein]
CTD
PMID:34273429
NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
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Nrarp
Notch-regulated ankyrin repeat protein
affects expression
ISO
monobutyl phthalate affects the expression of NRARP mRNA
CTD
PMID:19162170
NCBI chr 3:7,992,582...7,995,136
Ensembl chr 3:7,992,552...7,995,133
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Nrep
neuronal regeneration related protein
affects expression
ISO
monobutyl phthalate affects the expression of NREP mRNA
CTD
PMID:21195148
NCBI chr18:25,017,069...25,046,593
Ensembl chr18:25,017,083...25,046,591
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Nrf1
nuclear respiratory factor 1
decreases expression
EXP
monobutyl phthalate results in decreased expression of NRF1 mRNA
CTD
PMID:20864626
NCBI chr 4:58,664,932...58,772,328
Ensembl chr 4:58,664,957...58,825,328
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Nrip3
nuclear receptor interacting protein 3
increases expression
EXP
monobutyl phthalate results in increased expression of NRIP3 mRNA
CTD
PMID:29162477
NCBI chr 1:163,789,738...163,815,036
Ensembl chr 1:163,789,738...163,815,600
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Nudc
nuclear distribution C, dynein complex regulator
increases expression
ISO
monobutyl phthalate results in increased expression of NUDC protein
CTD
PMID:20553848
NCBI chr 5:145,758,006...145,771,390
Ensembl chr 5:145,758,002...145,771,425
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Nudt8
nudix hydrolase 8
increases expression
ISO
monobutyl phthalate results in increased expression of NUDT8 mRNA
CTD
PMID:35278568
NCBI chr 1:201,293,660...201,295,233
Ensembl chr 1:201,292,619...201,295,224
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Nupr1
nuclear protein 1, transcriptional regulator
affects expression
ISO
monobutyl phthalate affects the expression of NUPR1 mRNA
CTD
PMID:19162170
NCBI chr 1:181,213,292...181,215,327
Ensembl chr 1:181,213,368...181,215,281
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Ocln
occludin
decreases expression
EXP ISO
monobutyl phthalate results in decreased expression of OCLN protein
CTD
PMID:18214902 PMID:26922907
NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150
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Odad4
outer dynein arm docking complex subunit 4
affects expression
ISO
monobutyl phthalate affects the expression of ODAD4 mRNA
CTD
PMID:21195148
NCBI chr10:85,480,089...85,508,603
Ensembl chr10:85,480,094...85,508,603
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Olig1
oligodendrocyte transcription factor 1
decreases expression
ISO
monobutyl phthalate results in decreased expression of OLIG1 mRNA
CTD
PMID:35278568
NCBI chr11:30,514,379...30,516,521
Ensembl chr11:30,514,379...30,516,521
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Olr1177
olfactory receptor 1177
decreases expression
EXP
monobutyl phthalate results in decreased expression of OLR1177 mRNA
CTD
PMID:29162477
NCBI chr 8:18,326,449...18,327,387
Ensembl chr 8:18,326,449...18,327,387
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Olr951
olfactory receptor 951
decreases expression
EXP
monobutyl phthalate results in decreased expression of OLR951 mRNA
CTD
PMID:29162477
NCBI chr 7:3,591,905...3,592,849
Ensembl chr 7:3,822,551...3,823,495
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Or12j2b
olfactory receptor family 12 subfamily J member 2B
increases expression
EXP
monobutyl phthalate results in increased expression of OR12J2B mRNA
CTD
PMID:29162477
NCBI chr 1:195,315,038...195,315,949
Ensembl chr 1:195,315,038...195,315,949
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Or1e27b
olfactory receptor family 1 subfamily E member 27B
increases expression
EXP
monobutyl phthalate results in increased expression of OR1E27B mRNA
CTD
PMID:29162477
NCBI chr10:58,434,389...58,435,327
Ensembl chr10:58,434,389...58,435,327
G
Or1j15b
olfactory receptor family 1 subfamily J member 15B
decreases expression
EXP
monobutyl phthalate results in decreased expression of OR1J15B mRNA
CTD
PMID:29162477
NCBI chr 3:19,910,738...19,911,667
G
Or1l4b
olfactory receptor family 1 subfamily L member 4B
decreases expression
EXP
monobutyl phthalate results in decreased expression of OR1L4B mRNA
CTD
PMID:29162477
NCBI chr 3:20,699,266...20,700,189
Ensembl chr 3:20,692,167...20,700,766
G
Or1o11b
olfactory receptor family 1 subfamily O member 11B
decreases expression
EXP
monobutyl phthalate results in decreased expression of OR1O11B mRNA
CTD
PMID:29162477
NCBI chr20:1,111,816...1,112,745
Ensembl chr20:1,111,816...1,112,745
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Or2ak5e
olfactory receptor family 2 subfamily AK member 5E
increases expression
EXP
monobutyl phthalate results in increased expression of OR2AK5E mRNA
CTD
PMID:29162477
NCBI chr10:43,089,865...43,090,782
Ensembl chr10:43,087,519...43,093,395
G
Or2n1l
olfactory receptor family 2 subfamily N member 1L
decreases expression
EXP
monobutyl phthalate results in decreased expression of OR2N1L mRNA
CTD
PMID:29162477
NCBI chr20:340,574...341,512
G
Or2t47
olfactory receptor family 2 subfamily T member 47
increases expression
EXP
monobutyl phthalate results in increased expression of OR2T47 mRNA
CTD
PMID:29162477
NCBI chr10:42,917,545...42,918,492
Ensembl chr10:42,917,075...42,921,574
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Or4c109b
olfactory receptor family 4 subfamily C member 109B
increases expression
EXP
monobutyl phthalate results in increased expression of OR4C109B mRNA
CTD
PMID:29162477
NCBI chr 3:74,783,605...74,784,540
Ensembl chr 3:74,780,706...74,787,574
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Or4c127
olfactory receptor family 4 subfamily C member 127
increases expression
EXP
monobutyl phthalate results in increased expression of OR4C52 mRNA
CTD
PMID:29162477
NCBI chr 3:76,019,591...76,020,520
Ensembl chr 3:76,017,309...76,021,531
G
Or4c129
olfactory receptor family 4 subfamily C member 129
decreases expression
EXP
monobutyl phthalate results in decreased expression of OR4C129 mRNA
CTD
PMID:29162477
NCBI chr 3:74,229,531...74,230,439
Ensembl chr 3:74,228,788...74,235,647
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Or4p20b
olfactory receptor family 4 subfamily P member 20B
decreases expression
EXP
monobutyl phthalate results in decreased expression of OR4P20B mRNA
CTD
PMID:29162477
NCBI chr 3:74,022,169...74,023,089
Ensembl chr 3:74,022,169...74,023,089
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Or5af1b
olfactory receptor family 5 subfamily AF member 1B
increases expression
EXP
monobutyl phthalate results in increased expression of OR5AF1B mRNA
CTD
PMID:29162477
NCBI chr10:43,522,706...43,523,632
Ensembl chr10:43,521,310...43,525,334
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Or6c6h
olfactory receptor family 6 subfamily C member 6H
increases expression
EXP
monobutyl phthalate results in increased expression of OR6C6H mRNA
CTD
PMID:29162477
NCBI chr 7:3,822,551...3,823,929
Ensembl chr 7:3,822,551...3,823,495
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Or6d12b
olfactory receptor family 6 subfamily D member 12B
decreases expression
EXP
monobutyl phthalate results in decreased expression of OR6D12B mRNA
CTD
PMID:29162477
NCBI chr 4:149,717,772...149,718,755
Ensembl chr 4:149,693,790...149,720,747
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Or7g12
olfactory receptor family 7 subfamily G member 12
decreases expression
EXP
monobutyl phthalate results in decreased expression of OR7G12 mRNA
CTD
PMID:29162477
NCBI chr 8:16,574,372...16,575,310
Ensembl chr 8:16,574,372...16,575,310
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Or7g34b
olfactory receptor family 7 subfamily G member 34B
decreases expression
EXP
monobutyl phthalate results in decreased expression of OR7G34 mRNA
CTD
PMID:29162477
NCBI chr 8:17,498,328...17,499,266
Ensembl chr 8:17,498,328...17,499,275
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Or8h10c
olfactory receptor family 8 subfamily H member 10C
decreases expression
EXP
monobutyl phthalate results in decreased expression of OR8H10C mRNA
CTD
PMID:29162477
NCBI chr 3:72,046,706...72,047,671
Ensembl chr 3:72,046,706...72,047,671
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Oxct1
3-oxoacid CoA transferase 1
affects expression
ISO
monobutyl phthalate affects the expression of OXCT1 mRNA
CTD
PMID:21195148
NCBI chr 2:53,236,370...53,384,715
Ensembl chr 2:53,236,368...53,384,714
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Oxsr1
oxidative stress responsive kinase 1
increases expression
EXP
monobutyl phthalate results in increased expression of OXSR1 mRNA
CTD
PMID:20864626
NCBI chr 8:118,972,754...119,062,102
Ensembl chr 8:118,972,754...119,062,027
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P2rx1
purinergic receptor P2X 1
increases expression
EXP
monobutyl phthalate results in increased expression of P2RX1 mRNA
CTD
PMID:29162477
NCBI chr10:57,618,586...57,633,648
Ensembl chr10:57,618,586...57,633,623
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Pard3
par-3 family cell polarity regulator
affects expression
EXP
monobutyl phthalate affects the expression of PARD3 mRNA
CTD
PMID:20864626
NCBI chr19:55,080,282...55,630,111
Ensembl chr19:55,080,282...55,629,778
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Pax7
paired box 7
increases expression
EXP
monobutyl phthalate results in increased expression of PAX7 mRNA
CTD
PMID:29162477
NCBI chr 5:151,996,368...152,098,023
Ensembl chr 5:151,999,092...152,097,979
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Pcdh15
protocadherin related 15
decreases expression
EXP
monobutyl phthalate results in decreased expression of PCDH15 mRNA
CTD
PMID:29162477
NCBI chr20:13,997,094...15,496,446
Ensembl chr20:13,963,565...15,494,719
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Pcdhb5
protocadherin beta 5
increases expression
ISO
monobutyl phthalate results in increased expression of PCDHB4 mRNA
CTD
PMID:35278568
NCBI chr18:29,024,315...29,032,183
Ensembl chr18:29,028,382...29,053,259
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Pck1
phosphoenolpyruvate carboxykinase 1
multiple interactions
ISO
[monobutyl phthalate co-treated with Dexamethasone] results in increased expression of PCK1 mRNA; monobutyl phthalate promotes the reaction [Dexamethasone results in increased expression of PCK1 protein]
CTD
PMID:34273429
NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
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Pcna
proliferating cell nuclear antigen
decreases expression
ISO
monobutyl phthalate results in decreased expression of PCNA protein
CTD
PMID:38048874
NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
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Pcp4l1
Purkinje cell protein 4-like 1
increases expression
EXP
monobutyl phthalate results in increased expression of PCP4L1 mRNA
CTD
PMID:29162477
NCBI chr13:83,588,992...83,612,631
Ensembl chr13:83,588,992...83,609,966
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Pde11a
phosphodiesterase 11A
decreases expression
EXP
monobutyl phthalate results in decreased expression of PDE11A mRNA
CTD
PMID:20864626
NCBI chr 3:60,913,562...61,297,154
Ensembl chr 3:60,913,562...61,297,158
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Pde5a
phosphodiesterase 5A
decreases expression
EXP
monobutyl phthalate results in decreased expression of PDE5A mRNA
CTD
PMID:20864626
NCBI chr 2:210,858,515...211,003,480
Ensembl chr 2:210,858,063...210,999,701
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Pde6h
phosphodiesterase 6H
increases expression
EXP
monobutyl phthalate results in increased expression of PDE6H mRNA
CTD
PMID:29162477
NCBI chr 4:169,857,793...169,872,969
Ensembl chr 4:169,857,812...169,872,969
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Pdhx
pyruvate dehydrogenase complex, component X
decreases expression
EXP
monobutyl phthalate results in decreased expression of PDHX mRNA
CTD
PMID:20864626
NCBI chr 3:89,372,248...89,431,779
Ensembl chr 3:89,371,497...89,431,773
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Pdia3
protein disulfide isomerase family A, member 3
increases expression
ISO
monobutyl phthalate results in increased expression of PDIA3 protein
CTD
PMID:20553848
NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236
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Pdp1
pyruvate dehydrogenase phosphatase catalytic subunit 1
decreases expression
EXP
monobutyl phthalate results in decreased expression of PDP1 mRNA
CTD
PMID:29162477
NCBI chr 5:25,446,843...25,455,107
Ensembl chr 5:25,446,272...25,455,217
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Pdx1
pancreatic and duodenal homeobox 1
increases expression
ISO
monobutyl phthalate results in increased expression of PDX1 protein
CTD
PMID:38048874
NCBI chr12:7,757,865...7,763,064
Ensembl chr12:7,757,865...7,763,064
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Pdzk1ip1
PDZK1 interacting protein 1
decreases expression
EXP
monobutyl phthalate results in decreased expression of PDZK1IP1 mRNA
CTD
PMID:29162477
NCBI chr 5:128,618,050...128,623,131
Ensembl chr 5:128,618,237...128,623,131
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Peli2
pellino E3 ubiquitin protein ligase family member 2
decreases expression
EXP ISO
monobutyl phthalate results in decreased expression of PELI2 mRNA monobutyl phthalate results in decreased expression of PELI2 protein
CTD
PMID:29162477 PMID:32738922
NCBI chr15:21,393,262...21,537,737
Ensembl chr15:21,393,262...21,535,106
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Perm1
PPARGC1 and ESRR induced regulator, muscle 1
decreases expression
ISO
monobutyl phthalate results in decreased expression of PERM1 mRNA
CTD
PMID:35278568
NCBI chr 5:166,800,030...166,805,323
Ensembl chr 5:166,800,030...166,805,323
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Pfas
phosphoribosylformylglycinamidine synthase
multiple interactions
ISO
[mono(2-ethyl-5-hydroxyhexyl) phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono(2-ethyl-5-oxohexyl)phthalate co-treated with 2-ethyl-5-carboxypentyl phthalate co-treated with mono-isobutyl phthalate co-treated with mono-benzyl phthalate co-treated with monoethyl phthalate co-treated with monobutyl phthalate] affects the expression of PFAS mRNA
CTD
PMID:37160244
NCBI chr10:53,690,301...53,711,811
Ensembl chr10:53,691,626...53,708,420
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Pgam2
phosphoglycerate mutase 2
decreases expression
ISO
monobutyl phthalate results in decreased expression of PGAM2 protein
CTD
PMID:20553848
NCBI chr14:80,681,796...80,683,907
Ensembl chr14:80,681,776...80,683,940
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Pgk1
phosphoglycerate kinase 1
increases expression
ISO
monobutyl phthalate results in increased expression of PGK1 protein
CTD
PMID:20553848
NCBI chr X:71,271,454...71,287,429
Ensembl chr X:71,271,440...71,287,418
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Pgr
progesterone receptor
increases expression
EXP
monobutyl phthalate results in increased expression of PGR mRNA
CTD
PMID:20864626
NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
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Phb1
prohibitin 1
increases expression
ISO
monobutyl phthalate results in increased expression of PHB1 protein
CTD
PMID:20553848
NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042
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Phox2a
paired-like homeobox 2a
affects expression
ISO
monobutyl phthalate affects the expression of PHOX2A mRNA
CTD
PMID:19162170
NCBI chr 1:156,178,754...156,183,118
Ensembl chr 1:156,178,754...156,183,118
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Phykpl
5-phosphohydroxy-L-lysine phospho-lyase
decreases expression
EXP
monobutyl phthalate results in decreased expression of PHYKPL mRNA
CTD
PMID:29162477
NCBI chr10:35,839,965...35,863,631
Ensembl chr10:35,839,983...35,859,508
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Pigy
phosphatidylinositol glycan anchor biosynthesis, class Y
decreases expression
ISO
monobutyl phthalate results in decreased expression of PIGYL mRNA
CTD
PMID:35278568
NCBI chr 8:20,689,621...20,691,863
Ensembl chr 8:20,689,502...20,692,585
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Pitx2
paired-like homeodomain 2
decreases expression
EXP
monobutyl phthalate results in decreased expression of PITX2 mRNA
CTD
PMID:20864626
NCBI chr 2:217,717,738...217,737,293
Ensembl chr 2:217,717,693...217,737,293
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Pkn3
protein kinase N3
decreases expression
EXP
monobutyl phthalate results in decreased expression of PKN3 mRNA
CTD
PMID:29162477
NCBI chr 3:13,350,082...13,363,572
Ensembl chr 3:13,335,041...13,363,567
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Plac8
placenta associated 8
decreases expression
EXP
monobutyl phthalate results in decreased expression of PLAC8 mRNA
CTD
PMID:29162477
NCBI chr14:9,052,601...9,074,264
Ensembl chr14:9,063,048...9,074,264
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Plekha8
pleckstrin homology domain containing A8
decreases expression
EXP
monobutyl phthalate results in decreased expression of PLEKHA8 mRNA
CTD
PMID:29162477
NCBI chr 4:83,723,470...83,774,081
Ensembl chr 4:83,723,561...83,774,081
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Plin2
perilipin 2
affects expression increases expression
ISO
monobutyl phthalate affects the expression of PLIN2 mRNA monobutyl phthalate results in increased expression of PLIN2 mRNA
CTD
PMID:21195148 PMID:36736749
NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319
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Plin3
perilipin 3
decreases expression
ISO
monobutyl phthalate results in decreased expression of PLIN3 mRNA
CTD
PMID:35278568
NCBI chr 9:1,111,178...1,123,057
Ensembl chr 9:1,102,366...1,123,147
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Pls1
plastin 1
affects expression
ISO
monobutyl phthalate affects the expression of PLS1 mRNA
CTD
PMID:21195148
NCBI chr 8:96,316,703...96,426,592
Ensembl chr 8:96,317,849...96,385,195
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Plvap
plasmalemma vesicle associated protein
decreases expression
ISO
monobutyl phthalate results in decreased expression of PLVAP mRNA
CTD
PMID:35278568
NCBI chr16:18,184,985...18,197,301
Ensembl chr16:18,184,975...18,197,301
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Podxl2
podocalyxin-like 2
decreases expression
ISO
monobutyl phthalate results in decreased expression of PODXL2 mRNA
CTD
PMID:35278568
NCBI chr 4:121,306,224...121,338,070
Ensembl chr 4:121,306,224...121,338,112
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Ppara
peroxisome proliferator activated receptor alpha
decreases activity affects binding decreases expression
ISO
monobutyl phthalate results in decreased activity of PPARA protein monobutyl phthalate binds to PPARA protein monobutyl phthalate results in decreased expression of PPARA protein
CTD
PMID:16326050 PMID:23843199 PMID:38048874
NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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Ppard
peroxisome proliferator-activated receptor delta
affects binding multiple interactions increases expression
ISO
monobutyl phthalate binds to PPARB protein monobutyl phthalate inhibits the reaction [(4-(((2-(3-fluoro-4-(trifluoromethyl)phenyl)-4-methyl-1,3-thiazol-5-yl)methyl)sulfanyl)-2-methylphenoxy)acetic acid binds to and results in increased activity of PPARD protein] monobutyl phthalate results in increased expression of PPARD mRNA
CTD
PMID:16326050 PMID:23843199 PMID:36736749
NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
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Pparg
peroxisome proliferator-activated receptor gamma
affects binding multiple interactions increases expression affects expression affects localization decreases expression
ISO
monobutyl phthalate binds to PPARG protein monobutyl phthalate inhibits the reaction [ciglitazone binds to and results in increased activity of PPARG protein] monobutyl phthalate results in increased expression of PPARG protein monobutyl phthalate affects the expression of PPARG mRNA monobutyl phthalate affects the localization of PPARG protein monobutyl phthalate results in decreased expression of PPARG protein
CTD
PMID:16326050 PMID:23843199 PMID:28381288 PMID:29089286 PMID:36736749 PMID:38048874 More...
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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Ppox
protoporphyrinogen oxidase
decreases expression
EXP
monobutyl phthalate results in decreased expression of PPOX mRNA
CTD
PMID:29162477
NCBI chr13:83,697,661...83,701,998
Ensembl chr13:83,664,891...83,701,805
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Ppp1r18
protein phosphatase 1, regulatory subunit 18
affects expression
ISO
monobutyl phthalate affects the expression of PPP1R18 mRNA
CTD
PMID:21195148
NCBI chr20:2,877,567...2,887,526
Ensembl chr20:2,877,567...2,891,802
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Ppp1r1a
protein phosphatase 1, regulatory (inhibitor) subunit 1A
affects expression
ISO
monobutyl phthalate affects the expression of PPP1R1A mRNA
CTD
PMID:21195148
NCBI chr 7:134,654,578...134,662,236
Ensembl chr 7:134,654,579...134,662,230
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Prg2
proteoglycan 2, pro eosinophil major basic protein
decreases expression
EXP
monobutyl phthalate results in decreased expression of PRG2 mRNA
CTD
PMID:29162477
NCBI chr 3:70,062,535...70,066,102
Ensembl chr 3:70,062,535...70,066,101
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Prickle1
prickle planar cell polarity protein 1
affects expression
ISO
monobutyl phthalate affects the expression of PRICKLE1 mRNA
CTD
PMID:19162170
NCBI chr 7:124,639,142...124,735,027
Ensembl chr 7:124,639,142...124,658,113
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Prkcsh
PRKCSH beta subunit of glucosidase II
decreases expression
ISO
monobutyl phthalate results in decreased expression of PRKCSH protein
CTD
PMID:20553848
NCBI chr 8:20,534,787...20,546,493
Ensembl chr 8:20,534,880...20,546,492
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Prmt3
protein arginine methyltransferase 3
decreases expression
EXP
monobutyl phthalate results in decreased expression of PRMT3 mRNA
CTD
PMID:20864626
NCBI chr 1:99,492,712...99,581,774
Ensembl chr 1:99,492,724...99,579,435
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Prorsd1
prolyl-tRNA synthetase associated domain containing 1
decreases expression
EXP
monobutyl phthalate results in decreased expression of PRORSD1 mRNA
CTD
PMID:20864626
NCBI chr14:103,257,979...103,260,248
Ensembl chr14:103,257,979...103,260,248
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Prpf19
pre-mRNA processing factor 19
affects expression
EXP
monobutyl phthalate affects the expression of PRPF19 mRNA
CTD
PMID:20864626
NCBI chr 1:207,541,582...207,552,664
Ensembl chr 1:207,541,595...207,552,662
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Prss1
serine protease 1
decreases expression
EXP
monobutyl phthalate results in decreased expression of PRSS2 mRNA
CTD
PMID:29162477
NCBI chr 4:70,364,589...70,367,792
Ensembl chr 4:70,364,586...70,367,792
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Prss45
serine protease 45
increases expression
EXP
monobutyl phthalate results in increased expression of PRSS45 mRNA
CTD
PMID:29162477
NCBI chr 8:110,820,301...110,826,080
Ensembl chr 8:110,820,273...110,826,120
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Psmb8
proteasome 20S subunit beta 8
increases expression
ISO
monobutyl phthalate results in increased expression of PSMB8 mRNA
CTD
PMID:35278568
NCBI chr20:4,652,159...4,655,122
Ensembl chr20:4,652,159...4,655,283
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Psmc3ip
PSMC3 interacting protein
affects expression
ISO
monobutyl phthalate affects the expression of PSMC3IP mRNA
CTD
PMID:20421339
NCBI chr10:86,024,281...86,027,928
Ensembl chr10:86,023,950...86,027,423
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Ptgdr
prostaglandin D2 receptor
increases expression
EXP
monobutyl phthalate results in increased expression of PTGDR mRNA
CTD
PMID:29162477
NCBI chr15:17,360,304...17,367,679
Ensembl chr15:17,360,304...17,367,679
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Ptgfrn
prostaglandin F2 receptor inhibitor
increases expression
EXP
monobutyl phthalate results in increased expression of PTGFRN mRNA
CTD
PMID:20864626
NCBI chr 2:188,469,521...188,544,795
Ensembl chr 2:188,469,521...188,544,795
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Ptgs2
prostaglandin-endoperoxide synthase 2
affects expression
ISO
monobutyl phthalate affects the expression of PTGS2 mRNA
CTD
PMID:28381288
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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Ptpdc1
protein tyrosine phosphatase domain containing 1
decreases expression
EXP
monobutyl phthalate results in decreased expression of PTPDC1 mRNA
CTD
PMID:29162477
NCBI chr17:16,028,964...16,076,512
Ensembl chr17:16,049,382...16,076,512
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Pwp2
PWP2, small subunit processome component
decreases expression
EXP
monobutyl phthalate results in decreased expression of PWP2 mRNA
CTD
PMID:20864626
NCBI chr20:10,499,332...10,512,965
Ensembl chr20:10,499,363...10,513,640
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Pxmp2
peroxisomal membrane protein 2
affects expression
ISO
monobutyl phthalate affects the expression of PXMP2 mRNA
CTD
PMID:20421339
NCBI chr12:46,394,051...46,404,561
Ensembl chr12:46,394,193...46,404,557
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Qars1
glutaminyl-tRNA synthetase 1
increases expression
EXP
monobutyl phthalate results in increased expression of QARS1 mRNA
CTD
PMID:20864626
NCBI chr 8:109,207,705...109,215,738
Ensembl chr 8:109,207,705...109,215,739
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Qrsl1
glutaminyl-tRNA amidotransferase subunit QRSL1
decreases expression
EXP
monobutyl phthalate results in decreased expression of QRSL1 mRNA
CTD
PMID:20864626
NCBI chr20:47,357,206...47,382,160
Ensembl chr20:47,357,216...47,382,135
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Rab25
RAB25, member RAS oncogene family
affects expression
ISO
monobutyl phthalate affects the expression of RAB25 mRNA
CTD
PMID:20421339
NCBI chr 2:174,000,323...174,006,422
Ensembl chr 2:174,000,323...174,006,422
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Rab29
RAB29, member RAS oncogene family
decreases expression
ISO
monobutyl phthalate results in decreased expression of RAB29 mRNA
CTD
PMID:35278568
NCBI chr13:43,307,757...43,313,420
Ensembl chr13:43,307,775...43,313,417
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Rab3ip
RAB3A interacting protein
increases expression
EXP
monobutyl phthalate results in increased expression of RAB3IP mRNA
CTD
PMID:20864626
NCBI chr 7:52,531,461...52,575,295
Ensembl chr 7:52,532,401...52,561,043
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Rabgef1
RAB guanine nucleotide exchange factor 1
decreases expression
EXP
monobutyl phthalate results in decreased expression of RABGEF1 mRNA
CTD
PMID:20864626
NCBI chr12:26,459,190...26,503,790
Ensembl chr12:26,460,175...26,503,744
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Rabl3
RAB, member of RAS oncogene family-like 3
decreases expression
EXP
monobutyl phthalate results in decreased expression of RABL3 mRNA
CTD
PMID:20864626
NCBI chr11:63,153,281...63,182,240
Ensembl chr11:63,152,792...63,182,671
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Rad50
RAD50 double strand break repair protein
affects expression
EXP
monobutyl phthalate affects the expression of RAD50 mRNA
CTD
PMID:20864626
NCBI chr10:37,809,353...37,861,309
Ensembl chr10:37,808,726...37,861,396
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Rad51c
RAD51 paralog C
affects expression
ISO
monobutyl phthalate affects the expression of RAD51C mRNA
CTD
PMID:20421339
NCBI chr10:72,205,032...72,231,643
Ensembl chr10:72,205,032...72,231,248
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Ralbp1
ralA binding protein 1
affects expression
EXP
monobutyl phthalate affects the expression of RALBP1 mRNA
CTD
PMID:20864626
NCBI chr 9:105,456,425...105,493,235
Ensembl chr 9:105,456,425...105,492,707
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Ralgapa2
Ral GTPase activating protein catalytic subunit alpha 2
increases expression
EXP
monobutyl phthalate results in increased expression of RALGAPA2 mRNA
CTD
PMID:29162477
NCBI chr 3:133,658,725...133,938,821
Ensembl chr 3:133,659,761...133,938,916
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Rarb
retinoic acid receptor, beta
increases expression
EXP
monobutyl phthalate results in increased expression of RARB mRNA
CTD
PMID:29162477
NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288
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Rasd1
ras related dexamethasone induced 1
decreases expression
EXP
monobutyl phthalate results in decreased expression of RASD1 mRNA; monobutyl phthalate results in decreased expression of RASD1 protein
CTD
PMID:29162477
NCBI chr10:44,766,451...44,775,773
Ensembl chr10:44,766,455...44,768,186
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Rbbp7
RB binding protein 7, chromatin remodeling factor
affects expression
ISO
monobutyl phthalate affects the expression of RBBP7 mRNA
CTD
PMID:21195148
NCBI chr X:31,913,080...31,931,245
Ensembl chr X:31,913,081...31,931,226
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Rbm12
RNA binding motif protein 12
decreases expression
EXP
monobutyl phthalate results in decreased expression of RBM12 mRNA
CTD
PMID:20864626
NCBI chr 3:144,609,661...144,629,911
Ensembl chr 3:144,611,623...144,629,915 Ensembl chr 3:144,611,623...144,629,915
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Rbm38
RNA binding motif protein 38
affects expression
EXP
monobutyl phthalate affects the expression of RBM38 mRNA
CTD
PMID:20864626
NCBI chr 3:161,801,577...161,814,381
Ensembl chr 3:161,801,577...161,814,381
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Rbmx
RNA binding motif protein, X-linked
affects expression increases expression
ISO
monobutyl phthalate affects the expression of RBMX mRNA monobutyl phthalate results in increased expression of RBMX protein
CTD
PMID:20553848 PMID:21195148
NCBI chr X:135,305,237...135,314,806
Ensembl chr X:135,305,325...135,314,743
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Rela
RELA proto-oncogene, NF-kB subunit
multiple interactions increases phosphorylation increases expression
ISO
monobutyl phthalate results in increased phosphorylation of and results in increased expression of and results in increased activity of RELA protein; RELA affects the reaction [[monobutyl phthalate co-treated with CGB3 protein] results in increased secretion of Progesterone]; RELA affects the reaction [[monobutyl phthalate co-treated with Colforsin] results in increased secretion of Progesterone]; RELA affects the reaction [monobutyl phthalate results in increased expression of VIM mRNA]; RELA affects the reaction [monobutyl phthalate results in increased expression of VIM protein]; VIM inhibits the reaction [RELA affects the reaction [[monobutyl phthalate co-treated with CGB3 protein] results in increased secretion of Progesterone]] monobutyl phthalate results in increased phosphorylation of RELA protein monobutyl phthalate results in increased expression of RELA protein
CTD
PMID:26745512 PMID:28735033 PMID:35278568 PMID:38048874
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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Rhebl1
RHEB like 1
increases expression
EXP
monobutyl phthalate results in increased expression of RHEBL1 mRNA
CTD
PMID:20864626
NCBI chr 7:130,026,255...130,031,127
Ensembl chr 7:130,026,341...130,030,248
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Rhoc
ras homolog family member C
decreases expression
ISO
monobutyl phthalate results in decreased expression of RHOC protein
CTD
PMID:20553848
NCBI chr 2:192,287,065...192,293,292
Ensembl chr 2:192,287,130...192,295,306
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Rims2
regulating synaptic membrane exocytosis 2
decreases expression
EXP
monobutyl phthalate results in decreased expression of RIMS2 mRNA
CTD
PMID:20864626
NCBI chr 7:70,248,104...70,759,134
Ensembl chr 7:70,243,872...70,757,491
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Rnf135
ring finger protein 135
decreases expression
EXP
monobutyl phthalate results in decreased expression of RNF135 mRNA
CTD
PMID:29162477
NCBI chr10:65,170,560...65,189,791
Ensembl chr10:65,170,560...65,262,804
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Rnf151
ring finger protein 151
increases expression
EXP
monobutyl phthalate results in increased expression of RNF151 mRNA
CTD
PMID:29162477
NCBI chr10:13,742,682...13,747,192
Ensembl chr10:13,742,682...13,745,000
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Rnf166
ring finger protein 166
increases expression
EXP
monobutyl phthalate results in increased expression of RNF166 mRNA
CTD
PMID:20864626
NCBI chr19:50,529,434...50,539,274
Ensembl chr19:50,529,434...50,539,274
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Rnf182
ring finger protein 182
increases expression
EXP
monobutyl phthalate results in increased expression of RNF182 mRNA
CTD
PMID:29162477
NCBI chr17:21,026,110...21,081,760
Ensembl chr17:21,030,214...21,094,911
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Romo1
reactive oxygen species modulator 1
decreases expression
ISO
monobutyl phthalate results in decreased expression of ROMO1 mRNA
CTD
PMID:35278568
NCBI chr 3:144,659,709...144,661,310
Ensembl chr 3:144,659,826...144,661,310
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Rpia
ribose 5-phosphate isomerase A
decreases expression
EXP
monobutyl phthalate results in decreased expression of RPIA mRNA
CTD
PMID:20864626
NCBI chr 4:102,723,712...102,749,374
Ensembl chr 4:102,723,712...102,749,355
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Rpl18a
ribosomal protein L18A
decreases expression
ISO
monobutyl phthalate results in decreased expression of RPL18A protein
CTD
PMID:20553848
NCBI chr16:18,542,555...18,544,578
Ensembl chr16:18,542,566...18,545,546
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Rpl19l1
ribosomal protein L19 like 1
increases expression
EXP
monobutyl phthalate results in increased expression of RPL19L1 mRNA
CTD
PMID:29162477
NCBI chr 6:139,448,445...139,451,661
Ensembl chr 6:139,450,713...139,451,582
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Rpl23
ribosomal protein L23
affects expression
ISO
monobutyl phthalate affects the expression of RPL23 mRNA
CTD
PMID:21195148
NCBI chr10:82,771,878...82,775,840
Ensembl chr10:82,771,538...82,775,870
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Rpl29l6
ribosomal protein L29 like 6
increases expression
EXP
monobutyl phthalate results in increased expression of RPL29L6 mRNA
CTD
PMID:29162477
NCBI chr10:59,217,931...59,218,554
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Rpl5
ribosomal protein L5
increases expression
ISO
monobutyl phthalate results in increased expression of RPL5 protein
CTD
PMID:20553848
NCBI chr14:1,843,856...1,850,301
Ensembl chr14:1,843,770...1,850,290
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Rps10
ribosomal protein S10
decreases expression
ISO
monobutyl phthalate results in decreased expression of RPS10 protein
CTD
PMID:20553848
NCBI chr20:5,694,313...5,698,922
Ensembl chr20:5,694,313...5,699,044 Ensembl chr 6:5,694,313...5,699,044
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Rsad2
radical S-adenosyl methionine domain containing 2
increases expression
ISO
monobutyl phthalate results in increased expression of RSAD2 mRNA
CTD
PMID:35278568
NCBI chr 6:43,046,514...43,059,737
Ensembl chr 6:43,047,658...43,059,699
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Rsbn1l
round spermatid basic protein 1-like
increases expression
EXP
monobutyl phthalate results in increased expression of RSBN1L mRNA
CTD
PMID:29162477
NCBI chr 4:14,138,076...14,203,972
Ensembl chr 4:14,139,031...14,201,147
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Rsph4a
radial spoke head component 4A
affects expression
ISO
monobutyl phthalate affects the expression of RSPH4A mRNA
CTD
PMID:21195148
NCBI chr20:30,764,409...30,780,574
Ensembl chr20:30,764,409...30,780,574
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Rsph9
radial spoke head component 9
affects expression
ISO
monobutyl phthalate affects the expression of RSPH9 mRNA
CTD
PMID:21195148
NCBI chr 9:14,840,115...14,852,950
Ensembl chr 9:14,840,115...14,860,062
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Runx2
RUNX family transcription factor 2
affects expression
ISO
monobutyl phthalate affects the expression of RUNX2 mRNA
CTD
PMID:24704097
NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
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Rwdd2b
RWD domain containing 2B
decreases expression
EXP
monobutyl phthalate results in decreased expression of RWDD2B mRNA
CTD
PMID:20864626
NCBI chr11:26,665,877...26,677,986
Ensembl chr11:26,665,877...26,674,603
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S100a10
S100 calcium binding protein A10
affects expression
ISO
monobutyl phthalate affects the expression of S100A10 mRNA
CTD
PMID:19162170
NCBI chr 2:179,221,012...179,229,659
Ensembl chr 2:179,220,887...179,229,661
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Scd4
stearoyl-coenzyme A desaturase 4
increases expression
EXP
monobutyl phthalate results in increased expression of SCD4 mRNA
CTD
PMID:29162477
NCBI chr 1:243,203,433...243,216,007
Ensembl chr 1:243,203,881...243,215,148
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Scx
scleraxis bHLH transcription factor
decreases expression
ISO
monobutyl phthalate results in decreased expression of SCX mRNA
CTD
PMID:35278568
NCBI chr 7:108,176,608...108,178,626
Ensembl chr 7:108,176,608...108,178,626
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Sdf2l1
stromal cell-derived factor 2-like 1
decreases expression
ISO
monobutyl phthalate results in decreased expression of SDF2L1 mRNA
CTD
PMID:35278568
NCBI chr11:83,872,659...83,874,902
Ensembl chr11:83,872,659...83,874,902
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Sec14l4
SEC14-like lipid binding 4
affects expression
ISO
monobutyl phthalate affects the expression of SEC14L4 mRNA
CTD
PMID:21195148
NCBI chr14:78,912,750...78,928,799
Ensembl chr14:78,912,750...78,956,099
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Sema4d
semaphorin 4D
increases expression
EXP
monobutyl phthalate results in increased expression of SEMA4D mRNA
CTD
PMID:29162477
NCBI chr17:13,430,324...13,537,146
Ensembl chr17:13,430,379...13,537,138
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Septin9
septin 9
affects expression
EXP ISO
monobutyl phthalate affects the expression of SEPTIN9 mRNA
CTD
PMID:20421339 PMID:20864626
NCBI chr10:102,409,798...102,579,056
Ensembl chr10:102,409,711...102,579,055
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Serpina6
serpin family A member 6
decreases expression
ISO
monobutyl phthalate results in decreased expression of SERPINA6 mRNA
CTD
PMID:35278568
NCBI chr 6:122,780,040...122,790,274
Ensembl chr 6:122,780,043...122,790,349
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Serpine3
serpin family E member 3
decreases expression
EXP
monobutyl phthalate results in decreased expression of SERPINE3 mRNA
CTD
PMID:29162477
NCBI chr15:36,908,816...36,931,825
Ensembl chr15:36,907,131...36,933,150
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Sf1
splicing factor 1
affects expression
EXP
monobutyl phthalate affects the expression of SF1 mRNA
CTD
PMID:20864626
NCBI chr 1:203,670,016...203,683,432
Ensembl chr 1:203,670,018...203,684,330
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Sgsm2
small G protein signaling modulator 2
increases expression
EXP
monobutyl phthalate results in increased expression of SGSM2 mRNA
CTD
PMID:29162477
NCBI chr10:59,718,180...59,759,822
Ensembl chr10:59,718,183...59,759,447
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Sh2b2
SH2B adaptor protein 2
increases expression
EXP
monobutyl phthalate results in increased expression of APS mRNA
CTD
PMID:20864626
NCBI chr12:20,427,057...20,456,845
Ensembl chr12:20,429,043...20,456,844
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Sh2d7
SH2 domain containing 7
decreases expression
EXP
monobutyl phthalate results in decreased expression of SH2D7 mRNA
CTD
PMID:29162477
NCBI chr 8:54,918,399...54,930,129
Ensembl chr 8:54,918,406...54,929,726
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Sharpin
SHANK-associated RH domain interactor
increases expression
EXP
monobutyl phthalate results in increased expression of SHARPIN mRNA
CTD
PMID:20864626
NCBI chr 7:108,070,681...108,075,012
Ensembl chr 7:108,070,687...108,074,955
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Shbg
sex hormone binding globulin
decreases secretion
ISO
monobutyl phthalate results in decreased secretion of SHBG protein
CTD
PMID:24945889
NCBI chr10:54,332,939...54,350,409
Ensembl chr10:54,332,941...54,351,057
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Shc2
SHC adaptor protein 2
increases expression
ISO
monobutyl phthalate results in increased expression of SHC2 mRNA
CTD
PMID:35278568
NCBI chr 7:10,066,705...10,088,926
Ensembl chr 7:10,066,705...10,088,926
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Shisa2
shisa family member 2
decreases expression
ISO
monobutyl phthalate results in decreased expression of SHISA2 mRNA
CTD
PMID:35278568
NCBI chr15:33,806,715...33,811,013
Ensembl chr15:33,805,958...33,811,013
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Six2
SIX homeobox 2
affects expression
ISO
monobutyl phthalate affects the expression of SIX2 mRNA
CTD
PMID:21195148
NCBI chr 6:8,974,859...8,981,345
Ensembl chr 6:8,967,157...8,981,193
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Slc13a3
solute carrier family 13 member 3
increases expression
EXP
monobutyl phthalate results in increased expression of SLC13A3 mRNA
CTD
PMID:29162477
NCBI chr 3:154,141,878...154,204,604
Ensembl chr 3:154,141,872...154,204,606
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Slc16a3
solute carrier family 16 member 3
increases expression
ISO
monobutyl phthalate results in increased expression of SLC16A3 protein
CTD
PMID:36736749
NCBI chr10:106,212,679...106,222,564
Ensembl chr10:106,212,778...106,222,562
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Slc17a5
solute carrier family 17 member 5
increases expression
EXP
monobutyl phthalate results in increased expression of SLC17A5 mRNA
CTD
PMID:20864626
NCBI chr 8:79,394,416...79,429,387
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Slc22a20
solute carrier family 22 member 20
decreases expression
EXP
monobutyl phthalate results in decreased expression of SLC22A20 mRNA
CTD
PMID:29162477
NCBI chr 1:203,257,374...203,273,854
Ensembl chr 1:203,257,374...203,273,822
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Slc24a5
solute carrier family 24 member 5
increases expression
EXP
monobutyl phthalate results in increased expression of SLC24A5 mRNA
CTD
PMID:29162477
NCBI chr 3:112,319,349...112,338,889
Ensembl chr 3:112,319,308...112,339,231
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Slc25a37
solute carrier family 25 member 37
decreases expression
EXP
monobutyl phthalate results in decreased expression of SLC25A37 mRNA
CTD
PMID:20864626
NCBI chr15:44,534,280...44,576,697
Ensembl chr15:44,536,727...44,577,199
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Slc25a38
solute carrier family 25, member 38
affects expression
ISO
monobutyl phthalate affects the expression of SLC25A38 mRNA
CTD
PMID:21195148
NCBI chr 8:119,835,546...119,848,334
Ensembl chr 8:119,835,634...119,848,332
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Slc25a47
solute carrier family 25, member 47
increases expression
EXP
monobutyl phthalate results in increased expression of SLC25A47 mRNA
CTD
PMID:29162477
NCBI chr 6:127,767,365...127,773,000
Ensembl chr 6:127,767,305...127,773,005
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Slc27a1
solute carrier family 27 member 1
increases expression
ISO
monobutyl phthalate results in increased expression of FATP1 mRNA
CTD
PMID:36736749
NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063
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Slc27a3
solute carrier family 27 member 3
increases expression
EXP ISO
monobutyl phthalate results in increased expression of SLC27A3 mRNA monobutyl phthalate results in increased expression of FATP3 mRNA
CTD
PMID:29162477 PMID:36736749
NCBI chr 2:175,853,241...175,857,909
Ensembl chr 2:175,853,241...175,857,909
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Slc27a4
solute carrier family 27 member 4
increases expression
ISO
monobutyl phthalate results in increased expression of SLC27A4 mRNA
CTD
PMID:36736749
NCBI chr 3:13,075,022...13,087,943
Ensembl chr 3:13,075,022...13,087,943
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Slc2a1
solute carrier family 2 member 1
increases expression
ISO
monobutyl phthalate results in increased expression of SLC2A1 protein
CTD
PMID:36736749 PMID:38048874
NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
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Slc2a3
solute carrier family 2 member 3
increases expression
ISO
monobutyl phthalate results in increased expression of SLC2A3 protein
CTD
PMID:36736749
NCBI chr 4:155,960,944...156,026,000
Ensembl chr 4:155,960,946...156,025,472
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Slc30a7
solute carrier family 30 member 7
decreases expression
EXP
monobutyl phthalate results in decreased expression of SLC30A7 mRNA
CTD
PMID:20864626
NCBI chr 2:203,855,484...203,922,155
Ensembl chr 2:203,859,175...203,922,132
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Slc35g3
solute carrier family 35, member G3
increases expression
EXP
monobutyl phthalate results in increased expression of SLC35G3 mRNA
CTD
PMID:29162477
NCBI chr10:54,478,796...54,481,543
Ensembl chr10:54,479,770...54,481,748
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Slc44a3
solute carrier family 44, member 3
increases expression
EXP
monobutyl phthalate results in increased expression of SLC44A3 mRNA
CTD
PMID:29162477
NCBI chr 2:209,552,138...209,628,182
Ensembl chr 2:209,552,144...209,629,044
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Slc52a2
solute carrier family 52 member 2
decreases expression
EXP
monobutyl phthalate results in decreased expression of SLC52A2 mRNA
CTD
PMID:29162477
NCBI chr 7:108,246,003...108,267,642
Ensembl chr 7:108,262,612...108,268,034
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Slc7a4
solute carrier family 7, member 4
increases expression
EXP
monobutyl phthalate results in increased expression of SLC7A4 mRNA
CTD
PMID:29162477
NCBI chr11:83,435,093...83,439,078
Ensembl chr11:83,435,211...83,438,881
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Slc8b1
solute carrier family 8 member B1
increases expression
EXP
monobutyl phthalate results in increased expression of SLC8B1 mRNA
CTD
PMID:20864626
NCBI chr12:36,029,759...36,053,087
Ensembl chr12:36,029,760...36,053,031
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Sln
sarcolipin
affects expression
ISO
monobutyl phthalate affects the expression of SLN mRNA
CTD
PMID:19162170
NCBI chr 8:54,221,389...54,248,110
Ensembl chr 8:54,243,542...54,247,791
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Smad7
SMAD family member 7
affects expression
ISO
monobutyl phthalate affects the expression of SMAD7 mRNA
CTD
PMID:21195148
NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765
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Snora23
small nucleolar RNA, H/ACA box 23
increases expression
ISO
monobutyl phthalate results in increased expression of SNORA23 mRNA
CTD
PMID:35278568
NCBI chr 1:164,091,024...164,091,206
Ensembl chr 1:164,091,024...164,091,206
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Snora30
small nucleolar RNA, H/ACA box 30
increases expression
ISO
monobutyl phthalate results in increased expression of SNORA30 mRNA
CTD
PMID:35278568
NCBI chr 1:182,139,388...182,139,521
Ensembl chr 1:182,139,388...182,139,521
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Snx3
sorting nexin 3
increases expression
EXP
monobutyl phthalate results in increased expression of SNX3 mRNA
CTD
PMID:20864626
NCBI chr20:45,992,446...46,025,361
Ensembl chr20:45,992,720...46,025,379
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Socs1
suppressor of cytokine signaling 1
decreases expression
ISO
monobutyl phthalate results in decreased expression of SOCS1 mRNA; monobutyl phthalate results in decreased expression of SOCS1 protein
CTD
PMID:35278568
NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383
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Socs3
suppressor of cytokine signaling 3
decreases expression
ISO
monobutyl phthalate results in decreased expression of SOCS3 mRNA; monobutyl phthalate results in decreased expression of SOCS3 protein
CTD
PMID:35278568
NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
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Sod1
superoxide dismutase 1
multiple interactions
ISO
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of SOD1 mRNA
CTD
PMID:35861251
NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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Sox9
SRY-box transcription factor 9
decreases expression
ISO
monobutyl phthalate results in decreased expression of SOX9 mRNA
CTD
PMID:28496037
NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994
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Sp5
Sp5 transcription factor
affects expression
ISO
monobutyl phthalate affects the expression of SP5 mRNA
CTD
PMID:19162170
NCBI chr 3:55,274,931...55,277,733
Ensembl chr 3:55,274,931...55,277,733
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Sp9
Sp9 transcription factor
increases expression
EXP
monobutyl phthalate results in increased expression of SP9 mRNA
CTD
PMID:29162477
NCBI chr 3:58,146,826...58,149,357
Ensembl chr 3:58,146,826...58,149,357
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Spaca5
sperm acrosome associated 5
decreases expression
EXP
monobutyl phthalate results in decreased expression of SPACA5 mRNA
CTD
PMID:29162477
NCBI chr X:918,817...922,000
Ensembl chr X:918,817...922,049
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Specc1
sperm antigen with calponin homology and coiled-coil domains 1
affects expression
ISO
monobutyl phthalate affects the expression of SPECC1 mRNA
CTD
PMID:21195148
NCBI chr10:46,638,947...46,912,989
Ensembl chr10:46,638,809...46,912,802
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Spef1
sperm flagellar 1
affects expression
ISO
monobutyl phthalate affects the expression of SPEF1 mRNA
CTD
PMID:21195148
NCBI chr 3:118,390,659...118,396,842
Ensembl chr 3:118,390,575...118,394,531
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Spetex2e
Spetex-2E protein
increases expression
EXP
monobutyl phthalate results in increased expression of SPETEX2E mRNA
CTD
PMID:29162477
NCBI chr15:4,813,644...4,816,793
Ensembl chr15:4,739,331...4,816,815
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Sqstm1
sequestosome 1
increases expression
EXP
monobutyl phthalate results in increased expression of SQSTM1 mRNA
CTD
PMID:20864626
NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
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Srebf2
sterol regulatory element binding transcription factor 2
multiple interactions
ISO
monobutyl phthalate promotes the reaction [SREBF2 protein binds to STARD4 promoter]; SREBF2 protein affects the reaction [monobutyl phthalate results in increased abundance of Cholesterol Esters]
CTD
PMID:31705742
NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848
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Ssc4d
scavenger receptor cysteine rich family member with 4 domains
decreases expression
ISO
monobutyl phthalate results in decreased expression of SSC4D mRNA
CTD
PMID:35278568
NCBI chr12:20,702,931...20,723,732
Ensembl chr12:20,702,950...20,718,706
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Ssmem1
serine-rich single-pass membrane protein 1
decreases expression
ISO
monobutyl phthalate results in decreased expression of SSMEM1 mRNA
CTD
PMID:35278568
NCBI chr 4:59,128,730...59,139,029
Ensembl chr 4:59,128,730...59,145,007
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Star
steroidogenic acute regulatory protein
increases expression decreases expression
ISO
monobutyl phthalate results in increased expression of STAR mRNA; monobutyl phthalate results in increased expression of STAR protein monobutyl phthalate results in decreased expression of STAR protein
CTD
PMID:26745512 PMID:34280466 PMID:36602389
NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
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Stard4
StAR-related lipid transfer domain containing 4
decreases expression multiple interactions
EXP ISO
monobutyl phthalate results in decreased expression of STARD4 mRNA monobutyl phthalate promotes the reaction [SREBF2 protein binds to STARD4 promoter]; STARD4 protein affects the reaction [monobutyl phthalate results in increased abundance of Cholesterol Esters]
CTD
PMID:20864626 PMID:31705742
NCBI chr18:24,814,683...24,830,024
Ensembl chr18:24,817,107...24,830,024
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Stat3
signal transducer and activator of transcription 3
increases expression multiple interactions increases phosphorylation
ISO
monobutyl phthalate results in increased expression of STAT3 mRNA alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [monobutyl phthalate results in increased phosphorylation of STAT3 protein]; angoline inhibits the reaction [monobutyl phthalate results in increased expression of STAT3 mRNA]; LMT-28 inhibits the reaction [monobutyl phthalate results in increased phosphorylation of STAT3 protein]; monobutyl phthalate promotes the reaction [[STAT3 protein binds to GFAP promoter] which results in increased expression of GFAP protein]
CTD
PMID:35278568 PMID:37121744
NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
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Stim1
stromal interaction molecule 1
increases expression
EXP
monobutyl phthalate results in increased expression of STIM1 mRNA
CTD
PMID:20864626
NCBI chr 1:156,656,246...156,818,777
Ensembl chr 1:156,656,013...156,818,363
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Stxbp4
syntaxin binding protein 4
affects expression
ISO
monobutyl phthalate affects the expression of STXBP4 mRNA
CTD
PMID:20421339
NCBI chr10:75,301,868...75,458,741
Ensembl chr10:75,305,463...75,458,663
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Supt16h
SPT16 homolog, facilitates chromatin remodeling subunit
decreases expression
ISO
monobutyl phthalate results in decreased expression of SUPT16H protein
CTD
PMID:20553848
NCBI chr15:24,867,697...24,904,818
Ensembl chr15:24,866,489...24,904,846
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Syn1
synapsin I
multiple interactions increases expression
ISO
Gabapentin inhibits the reaction [monobutyl phthalate results in increased expression of SYN1 protein] monobutyl phthalate results in increased expression of SYN1 mRNA; monobutyl phthalate results in increased expression of SYN1 protein
CTD
PMID:35278568
NCBI chr X:1,172,208...1,227,400
Ensembl chr X:1,172,208...1,227,396
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Syndig1
synapse differentiation inducing 1
decreases expression
EXP
monobutyl phthalate results in decreased expression of SYNDIG1 mRNA
CTD
PMID:29162477
NCBI chr 3:138,030,995...138,234,646
Ensembl chr 3:138,031,769...138,198,122
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Synpo
synaptopodin
decreases expression
ISO
monobutyl phthalate results in decreased expression of SYNPO mRNA
CTD
PMID:35278568
NCBI chr18:54,048,299...54,106,388
Ensembl chr18:54,026,152...54,102,126
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Syp
synaptophysin
increases expression
ISO
monobutyl phthalate results in increased expression of SYP protein
CTD
PMID:35278568
NCBI chr X:14,849,444...14,864,553
Ensembl chr X:14,849,444...14,864,745
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Syt2
synaptotagmin 2
increases expression
ISO
monobutyl phthalate results in increased expression of SYT2 mRNA
CTD
PMID:35278568
NCBI chr13:46,088,046...46,197,976
Ensembl chr13:46,185,282...46,193,859
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Syt4
synaptotagmin 4
increases expression
ISO
monobutyl phthalate results in increased expression of SYT4 mRNA
CTD
PMID:35278568
NCBI chr18:23,036,973...23,046,380
Ensembl chr18:23,038,378...23,046,332
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Sytl1
synaptotagmin-like 1
decreases expression
ISO
monobutyl phthalate results in decreased expression of SYTL1 mRNA
CTD
PMID:35278568
NCBI chr 5:145,452,524...145,462,940
Ensembl chr 5:145,422,669...145,462,940
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Szt2
SZT2 subunit of KICSTOR complex
increases expression
EXP
monobutyl phthalate results in increased expression of SZT2 mRNA
CTD
PMID:29162477
NCBI chr 5:131,897,250...131,943,953
Ensembl chr 5:131,897,275...131,943,904
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Taf1
TATA-box binding protein associated factor 1
affects expression
EXP
monobutyl phthalate affects the expression of TAF1 mRNA
CTD
PMID:20864626
NCBI chr X:66,640,915...66,716,543
Ensembl chr X:66,640,982...66,716,543
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Taf1d
TATA-box binding protein associated factor, RNA polymerase I subunit D
decreases expression
EXP
monobutyl phthalate results in decreased expression of TAF1D mRNA
CTD
PMID:20864626
NCBI chr 8:12,146,511...12,156,647
Ensembl chr 8:12,146,605...12,156,618
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Tbc1d8b
TBC1 domain family member 8B
increases expression
EXP
monobutyl phthalate results in increased expression of TBC1D8B mRNA
CTD
PMID:20864626
NCBI chr X:103,319,181...103,407,137
Ensembl chr X:103,319,340...103,407,133
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Tbrg4
transforming growth factor beta regulator 4
decreases expression
EXP
monobutyl phthalate results in decreased expression of TBRG4 mRNA
CTD
PMID:20864626
NCBI chr14:81,481,977...81,490,781
Ensembl chr14:81,481,981...81,490,756
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Tbxt
T-box transcription factor T
affects expression
ISO
monobutyl phthalate affects the expression of T mRNA
CTD
PMID:19162170
NCBI chr 1:52,298,104...52,309,813
Ensembl chr 1:52,298,099...52,305,864
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Tceal8
transcription elongation factor A like 8
affects expression
ISO
monobutyl phthalate affects the expression of TCEAL8 mRNA
CTD
PMID:19162170
NCBI chr X:99,171,307...99,173,377
Ensembl chr X:99,171,177...99,173,710
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Tcp1
t-complex 1
decreases expression
ISO
monobutyl phthalate results in decreased expression of TCP1 protein
CTD
PMID:20553848
NCBI chr 1:47,829,061...47,836,809
Ensembl chr 1:47,828,652...47,836,839
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Tcp11x2
t-complex 11 family, X-linked 2
increases expression
ISO
monobutyl phthalate results in increased expression of TCP11X2 mRNA
CTD
PMID:35278568
NCBI chr X:98,591,191...98,640,800
Ensembl chr X:98,591,189...98,640,763
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Tent5b
terminal nucleotidyltransferase 5B
decreases expression
ISO
monobutyl phthalate results in decreased expression of FAM46B mRNA
CTD
PMID:35278568
NCBI chr 5:145,695,358...145,702,668
Ensembl chr 5:145,695,362...145,706,073
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Tent5c
terminal nucleotidyltransferase 5C
decreases expression
EXP
monobutyl phthalate results in decreased expression of TENT5C mRNA
CTD
PMID:29162477
NCBI chr 2:187,853,026...187,875,260
Ensembl chr 2:187,853,024...187,894,744
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Testin
testin gene
increases expression
EXP
monobutyl phthalate results in increased expression of TESTIN mRNA
CTD
PMID:29162477
NCBI chr17:3,824,222...3,859,385
Ensembl chr17:3,846,899...3,859,385
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Tigd3
tigger transposable element derived 3
increases expression
EXP
monobutyl phthalate results in increased expression of TIGD3 mRNA
CTD
PMID:29162477
NCBI chr 1:203,178,456...203,182,775
Ensembl chr 1:203,178,460...203,181,272
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Timeless
timeless circadian regulator
affects expression
EXP
monobutyl phthalate affects the expression of TIMELESS mRNA
CTD
PMID:20864626
NCBI chr 7:654,804...678,769
Ensembl chr 7:654,822...678,738
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Tjp1
tight junction protein 1
decreases expression
EXP ISO
monobutyl phthalate results in decreased expression of TJP1 protein
CTD
PMID:18214902 PMID:26922907
NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432
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Tktl2
transketolase-like 2
increases expression
EXP
monobutyl phthalate results in increased expression of TKTL2 mRNA
CTD
PMID:29162477
NCBI chr16:23,202,460...23,209,741
Ensembl chr16:23,202,453...23,209,742
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Tlcd1
TLC domain containing 1
decreases expression
EXP
monobutyl phthalate results in decreased expression of TLCD1 mRNA
CTD
PMID:20864626
NCBI chr10:63,074,469...63,076,502
Ensembl chr10:63,074,469...63,076,501
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Tm4sf1
transmembrane 4 L six family member 1
decreases expression
EXP
monobutyl phthalate results in decreased expression of TM4SF1 mRNA
CTD
PMID:29162477
NCBI chr 2:141,456,950...141,466,146
Ensembl chr 2:141,453,310...141,466,146
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Tmco5a
transmembrane and coiled-coil domains 5A
decreases expression
EXP
monobutyl phthalate results in decreased expression of TMCO5A mRNA
CTD
PMID:29162477
NCBI chr 3:103,732,936...103,746,242
Ensembl chr 3:103,732,945...103,746,249
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Tmed5
transmembrane p24 trafficking protein 5
decreases expression
EXP
monobutyl phthalate results in decreased expression of TMED5 mRNA
CTD
PMID:20864626
NCBI chr14:1,607,895...1,619,028
Ensembl chr14:1,607,819...1,628,426
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Tmem151b
transmembrane protein 151B
increases expression
EXP
monobutyl phthalate results in increased expression of TMEM151B mRNA
CTD
PMID:29162477
NCBI chr 9:15,456,446...15,464,289
Ensembl chr 9:15,455,801...15,464,302
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Tmem235
transmembrane protein 235
increases expression
ISO
monobutyl phthalate results in increased expression of TMEM235 mRNA
CTD
PMID:35278568
NCBI chr10:103,081,716...103,092,187
Ensembl chr10:103,086,497...103,092,184
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Tmem59l
transmembrane protein 59-like
decreases expression
EXP
monobutyl phthalate results in decreased expression of TMEM59L mRNA
CTD
PMID:29162477
NCBI chr16:18,941,370...18,945,381
Ensembl chr16:18,941,567...18,945,381
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Tmem69
transmembrane protein 69
decreases expression
EXP
monobutyl phthalate results in decreased expression of TMEM69 mRNA
CTD
PMID:20864626
NCBI chr 5:130,004,888...130,008,466
Ensembl chr 5:130,004,901...130,010,655
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Tmem9b
TMEM9 domain family, member B
affects expression
ISO
monobutyl phthalate affects the expression of TMEM9B mRNA
CTD
PMID:20421339
NCBI chr 1:163,755,307...163,783,880
Ensembl chr 1:163,764,433...163,783,278
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Tnf
tumor necrosis factor
increases expression multiple interactions
ISO
monobutyl phthalate results in increased expression of TNF mRNA angoline inhibits the reaction [monobutyl phthalate results in increased expression of TNF mRNA]
CTD
PMID:37121744
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Tnfrsf19
TNF receptor superfamily member 19
increases expression
EXP
monobutyl phthalate results in increased expression of TNFRSF19 mRNA
CTD
PMID:20864626
NCBI chr15:35,092,206...35,158,472
Ensembl chr15:35,092,206...35,180,795
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Tnks2
tankyrase 2
increases expression
EXP
monobutyl phthalate results in increased expression of TNKS2 mRNA
CTD
PMID:20864626
NCBI chr 1:234,567,888...234,621,079
Ensembl chr 1:234,567,858...234,621,079
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Tox3
TOX high mobility group box family member 3
affects expression
ISO
monobutyl phthalate affects the expression of TOX3 mRNA
CTD
PMID:21195148
NCBI chr19:16,648,338...16,757,151
Ensembl chr19:16,648,342...16,757,148
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Tp53
tumor protein p53
affects expression decreases expression increases methylation
EXP ISO
monobutyl phthalate affects the expression of TRP53 mRNA monobutyl phthalate results in decreased expression of TP53 mRNA monobutyl phthalate results in increased methylation of TP53 promoter
CTD
PMID:20864626 PMID:35487445
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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Tpra1
transmembrane protein adipocyte associated 1
increases expression
EXP
monobutyl phthalate results in increased expression of TPRA1 mRNA
CTD
PMID:20864626
NCBI chr 4:121,364,093...121,375,275
Ensembl chr 4:121,364,091...121,375,269
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Tram1l1
translocation associated membrane protein 1-like 1
increases expression
ISO
monobutyl phthalate results in increased expression of TRAM1L1 mRNA
CTD
PMID:35278568
NCBI chr 2:212,511,130...212,513,311
G
Trdmt1
tRNA aspartic acid methyltransferase 1
decreases expression
EXP
monobutyl phthalate results in decreased expression of TRDMT1 mRNA
CTD
PMID:29162477
NCBI chr17:76,601,966...76,646,104
Ensembl chr17:76,610,543...76,645,439
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Trh
thyrotropin releasing hormone
decreases expression
EXP
monobutyl phthalate results in decreased expression of TRH mRNA
CTD
PMID:29162477
NCBI chr 4:124,742,111...124,777,094
Ensembl chr 4:124,742,111...124,744,637
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Trim2
tripartite motif-containing 2
increases expression
EXP
monobutyl phthalate results in increased expression of TRIM2 mRNA
CTD
PMID:29162477
NCBI chr 2:169,500,628...169,652,855
Ensembl chr 2:169,500,634...169,652,927
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Trim45
tripartite motif-containing 45
increases expression
EXP
monobutyl phthalate results in increased expression of TRIM45 mRNA
CTD
PMID:29162477
NCBI chr 2:188,349,979...188,359,205
Ensembl chr 2:188,349,744...188,359,204
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Trim6
tripartite motif containing 6
affects expression
ISO
monobutyl phthalate affects the expression of TRIM6 mRNA
CTD
PMID:21195148
NCBI chr 1:158,683,746...158,696,936
Ensembl chr 1:158,683,746...158,696,914
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Tubb5
tubulin, beta 5 class I
increases expression
ISO
monobutyl phthalate results in increased expression of TUBB5 protein
CTD
PMID:20553848
NCBI chr20:2,912,779...2,916,928
Ensembl chr20:2,912,778...2,916,940
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Txnip
thioredoxin interacting protein
affects expression
ISO
monobutyl phthalate affects the expression of TXNIP mRNA
CTD
PMID:21195148
NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
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Tyms
thymidylate synthetase
decreases expression
EXP
monobutyl phthalate results in decreased expression of TYMS mRNA
CTD
PMID:20864626
NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536
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Tyw5
tRNA-yW synthesizing protein 5
decreases expression
EXP
monobutyl phthalate results in decreased expression of TYW5 mRNA
CTD
PMID:20864626
NCBI chr 9:58,961,100...58,979,188
Ensembl chr 9:58,961,106...58,979,188
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Uap1l1
UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
affects expression
ISO
monobutyl phthalate affects the expression of UAP1L1 mRNA
CTD
PMID:21195148
NCBI chr 3:8,172,335...8,180,505
Ensembl chr 3:8,173,216...8,180,443
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Ube2n
ubiquitin-conjugating enzyme E2N
increases expression
EXP
monobutyl phthalate results in increased expression of UBE2N mRNA
CTD
PMID:29162477
NCBI chr 7:30,154,330...30,184,373
Ensembl chr 7:30,154,616...30,184,355
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Ubiad1
UbiA prenyltransferase domain containing 1
decreases expression
EXP
monobutyl phthalate results in decreased expression of UBIAD1 mRNA
CTD
PMID:20864626
NCBI chr 5:158,856,582...158,880,490
Ensembl chr 5:158,868,672...158,880,271
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Unc13b
unc-13 homolog B
affects expression
ISO
monobutyl phthalate affects the expression of UNC13B mRNA
CTD
PMID:20421339
NCBI chr 5:57,288,999...57,504,110
Ensembl chr 5:57,289,227...57,502,926
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Unc13c
unc-13 homolog C
increases expression
EXP
monobutyl phthalate results in increased expression of UNC13C mRNA
CTD
PMID:29162477
NCBI chr 8:74,247,026...74,697,629
Ensembl chr 8:74,247,899...74,673,223
G
Upp1
uridine phosphorylase 1
affects expression
ISO
monobutyl phthalate affects the expression of UPP1 mRNA
CTD
PMID:19162170
NCBI chr14:83,809,495...83,829,299
Ensembl chr14:83,809,960...83,829,462
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Usp11
ubiquitin specific peptidase 11
increases expression
EXP
monobutyl phthalate results in increased expression of USP11 mRNA
CTD
PMID:20864626
NCBI chr X:1,473,349...1,489,520
Ensembl chr X:1,473,350...1,489,520
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Usp9y
ubiquitin specific peptidase 9, Y-linked
increases expression
ISO
monobutyl phthalate results in increased expression of USP9Y mRNA
CTD
PMID:35278568
NCBI chr Y:1,156,135...1,300,965
Ensembl chr Y:1,156,135...1,300,943
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Utp18
UTP18 small subunit processome component
decreases expression
EXP
monobutyl phthalate results in decreased expression of UTP18 mRNA
CTD
PMID:20864626
NCBI chr10:78,811,879...78,839,338
Ensembl chr10:78,811,880...78,839,627
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Vim
vimentin
decreases methylation multiple interactions increases expression
ISO
monobutyl phthalate results in decreased methylation of VIM promoter 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [monobutyl phthalate results in increased expression of VIM mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [monobutyl phthalate results in increased expression of VIM protein]; RELA affects the reaction [monobutyl phthalate results in increased expression of VIM mRNA]; RELA affects the reaction [monobutyl phthalate results in increased expression of VIM protein]; S-Adenosylmethionine inhibits the reaction [monobutyl phthalate results in increased expression of VIM mRNA]; S-Adenosylmethionine inhibits the reaction [monobutyl phthalate results in increased expression of VIM protein]; VIM affects the reaction [[monobutyl phthalate co-treated with CGB3 protein] results in increased secretion of Progesterone]; VIM affects the reaction [[monobutyl phthalate co-treated with Colforsin] results in increased secretion of Progesterone]; VIM inhibits the reaction [RELA affects the reaction [[monobutyl phthalate co-treated with CGB3 protein] results in increased secretion of Progesterone]] monobutyl phthalate results in increased expression of VIM mRNA; monobutyl phthalate results in increased expression of VIM protein
CTD
PMID:20553848 PMID:26745512 PMID:28735033
NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
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Vom1r1
vomeronasal 1 receptor 1
increases expression
EXP
monobutyl phthalate results in increased expression of VOM1R1 mRNA
CTD
PMID:29162477
NCBI chr 1:54,543,173...54,544,143
Ensembl chr 1:54,540,995...54,547,858
G
Vom1r49
vomeronasal 1 receptor 49
decreases expression
EXP
monobutyl phthalate results in decreased expression of VOM1R49 mRNA
CTD
PMID:29162477
NCBI chr 1:72,501,787...72,502,731
G
Vom2r71
vomeronasal 2 receptor, 71
increases expression
EXP
monobutyl phthalate results in increased expression of VOM2R71 mRNA
CTD
PMID:29162477
NCBI chr14:691,705...716,053
Ensembl chr14:691,705...716,053
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Wbp11-ps3
WW domain binding protein 11, pseudogene 3
decreases expression
EXP
monobutyl phthalate results in decreased expression of WBP11-PS3 mRNA
CTD
PMID:29162477
NCBI chr 6:107,227,781...107,230,018
G
Wdr43
WD repeat domain 43
decreases expression
EXP
monobutyl phthalate results in decreased expression of WDR43 mRNA
CTD
PMID:20864626
NCBI chr 6:23,845,499...23,884,846
Ensembl chr 6:23,845,499...23,884,846
G
Wdr6
WD repeat domain 6
affects expression
ISO
monobutyl phthalate affects the expression of WDR6 mRNA
CTD
PMID:21195148
NCBI chr 8:109,268,079...109,274,504
Ensembl chr 8:109,268,079...109,274,499
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Wnt3
Wnt family member 3
affects expression
ISO
monobutyl phthalate affects the expression of WNT3 mRNA
CTD
PMID:19162170
NCBI chr10:88,680,198...88,724,170
Ensembl chr10:88,680,248...88,724,099
G
Wnt8a
Wnt family member 8A
affects expression
ISO
monobutyl phthalate affects the expression of WNT8A mRNA
CTD
PMID:19162170 PMID:21195148
NCBI chr18:26,137,690...26,143,283
Ensembl chr18:26,137,690...26,143,283
G
Xkr5
XK related 5
decreases expression
EXP
monobutyl phthalate results in decreased expression of XKR5 mRNA
CTD
PMID:20864626
NCBI chr16:70,874,983...70,892,972
Ensembl chr16:70,875,093...70,892,967
G
Xrcc1
X-ray repair cross complementing 1
affects expression
EXP
monobutyl phthalate affects the expression of XRCC1 mRNA
CTD
PMID:20864626
NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701
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Ybx1
Y box binding protein 1
decreases expression
ISO
monobutyl phthalate results in decreased expression of YBX1 protein
CTD
PMID:20553848
NCBI chr 5:132,882,137...132,898,885
Ensembl chr 5:132,882,145...132,898,862
G
Ywhaq
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
decreases expression
ISO
monobutyl phthalate results in decreased expression of YWHAQ protein
CTD
PMID:20553848
NCBI chr 6:40,935,714...40,966,240
Ensembl chr 6:40,935,949...40,966,273
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Zbed5
zinc finger BED-type containing 5
decreases expression
ISO
monobutyl phthalate results in decreased expression of ZBED5 mRNA
CTD
PMID:35278568
NCBI chr12:26,807,652...26,813,706
Ensembl chr12:26,807,600...26,813,664
G
Zfp105
zinc finger protein 105
affects expression
ISO
monobutyl phthalate affects the expression of ZFP105 mRNA
CTD
PMID:19162170
NCBI chr 8:122,567,229...122,578,696
Ensembl chr 8:122,567,214...122,578,692
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Zfp185
zinc finger protein 185
affects expression
ISO
monobutyl phthalate affects the expression of ZFP185 mRNA
CTD
PMID:21195148
NCBI chr X:150,831,869...150,877,652
Ensembl chr X:150,831,862...150,874,810
G
Zfp276
zinc finger protein (C2H2 type) 276
decreases expression
EXP
monobutyl phthalate results in decreased expression of ZFP276 mRNA
CTD
PMID:20864626
NCBI chr19:51,291,005...51,304,240
Ensembl chr19:51,290,777...51,304,049
G
Zfp366
zinc finger protein 366
increases expression
EXP
monobutyl phthalate results in increased expression of ZFP366 mRNA
CTD
PMID:29162477
NCBI chr 2:30,578,552...30,640,546
Ensembl chr 2:30,578,715...30,642,182
G
Zfp384
zinc finger protein 384
increases expression
EXP
monobutyl phthalate results in increased expression of ZFP384 mRNA
CTD
PMID:29162477
NCBI chr 4:157,810,263...157,840,052
Ensembl chr 4:157,810,352...157,839,766
G
Zfp518a
zinc finger protein 518A
affects expression
ISO
monobutyl phthalate affects the expression of ZFP518A mRNA
CTD
PMID:20421339
NCBI chr 1:239,719,305...239,744,978
Ensembl chr 1:239,719,505...239,744,979
G
Zfp748
zinc finger protein 748
decreases expression
EXP
monobutyl phthalate results in decreased expression of ZFP748 mRNA
CTD
PMID:29162477
NCBI chr 1:35,075,408...35,091,416
Ensembl chr 1:35,074,172...35,091,389
G
Zfp771
zinc finger protein 771
affects expression
ISO
monobutyl phthalate affects the expression of ZFP771 mRNA
CTD
PMID:21195148
NCBI chr 1:181,864,035...181,875,136
Ensembl chr 1:181,864,219...181,875,141
G
Zfp870
zinc finger protein 870
decreases expression
EXP
monobutyl phthalate results in decreased expression of ZFP870 mRNA
CTD
PMID:29162477
NCBI chr 7:11,990,146...12,003,813
Ensembl chr 7:11,990,148...12,003,813
G
Zhx2
zinc fingers and homeoboxes 2
decreases expression
EXP
monobutyl phthalate results in decreased expression of ZHX2 mRNA
CTD
PMID:29162477
NCBI chr 7:89,226,358...89,374,266
Ensembl chr 7:89,226,463...89,374,378
G
Znf48
zinc finger protein 48
decreases expression
EXP
monobutyl phthalate results in decreased expression of ZFP553 mRNA
CTD
PMID:20864626
NCBI chr 1:181,854,481...181,858,987
Ensembl chr 1:181,853,787...181,859,139
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