CHEBI ONTOLOGY - ANNOTATIONS |
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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
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Term: | raloxifene |
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Accession: | CHEBI:8772
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browse the term
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Definition: | A member of the class of 1-benzothiophenes that is 1-benzothiophene in which the hydrogens at positions 2, 3, and 6 have been replaced by p-hydroxyphenyl, p-[2-(piperidin-1-yl)ethoxy]benzoyl, and hydroxy groups, respectively. |
Synonyms: | exact_synonym: | [6-hydroxy-2-(4-hydroxyphenyl)-1-benzothien-3-yl][4-(2-piperidin-1-ylethoxy)phenyl]methanone |
| related_synonym: | (2-(4-Hydroxyphenyl)-6-hydroxybenzo(b)thien-3-yl)(4-(2-(1-piperidinyl)ethoxy)phenyl)methanone; Formula=C28H27NO4S; InChI=1S/C28H27NO4S/c30-21-8-4-20(5-9-21)28-26(24-13-10-22(31)18-25(24)34-28)27(32)19-6-11-23(12-7-19)33-17-16-29-14-2-1-3-15-29/h4-13,18,30-31H,1-3,14-17H2; InChIKey=GZUITABIAKMVPG-UHFFFAOYSA-N; LY 139481; SMILES=S1C(=C(C2=C1C=C(O)C=C2)C(=O)C3=CC=C(OCCN4CCCCC4)C=C3)C5=CC=C(O)C=C5; raloxifeno; raloxifenum |
| alt_id: | CHEBI:45355 |
| xref: | Beilstein:4890356; CAS:84449-90-1; DrugBank:DB00481; Drug_Central:2351; KEGG:C07228; KEGG:D08465; LINCS:LSM-3425 |
| xref_mesh: | MESH:D020849 |
| xref: | PDBeChem:RAL; Patent:EP62503; Patent:US4418068; Wikipedia:Raloxifene |
| cyclic_relationship: | is_conjugate_base_of CHEBI:90191 |
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Aatk |
apoptosis-associated tyrosine kinase |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of AATK mRNA |
CTD |
PMID:15576828 |
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NCBI chr11:119,898,137...119,938,009
Ensembl chr11:119,898,139...119,937,993
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Abcb1a |
ATP-binding cassette, sub-family B member 1A |
decreases expression multiple interactions affects activity |
ISO |
Raloxifene Hydrochloride results in decreased expression of ABCB1 mRNA; Raloxifene Hydrochloride results in decreased expression of ABCB1 protein [Cyclosporine co-treated with Raloxifene Hydrochloride] results in decreased expression of ABCB1 mRNA; [Cyclosporine co-treated with Raloxifene Hydrochloride] results in decreased expression of ABCB1 protein ABCB1 protein affects the activity of Raloxifene Hydrochloride |
CTD |
PMID:16959878 PMID:17096884 |
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NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575
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Abcb9 |
ATP-binding cassette, sub-family B member 9 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ABCB9 mRNA |
CTD |
PMID:14699072 |
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NCBI chr 5:124,199,920...124,234,009
Ensembl chr 5:124,199,593...124,233,861
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Abcc1 |
ATP-binding cassette, sub-family C member 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ABCC1 mRNA |
CTD |
PMID:19059307 |
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NCBI chr16:14,179,317...14,292,743
Ensembl chr16:14,179,422...14,293,601
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Abcg1 |
ATP binding cassette subfamily G member 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ABCG1 mRNA |
CTD |
PMID:14699072 |
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NCBI chr17:31,276,668...31,336,958
Ensembl chr17:31,276,649...31,336,962
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Abhd2 |
abhydrolase domain containing 2 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of ABHD2 mRNA |
CTD |
PMID:26865669 |
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NCBI chr 7:78,923,002...79,015,257
Ensembl chr 7:78,922,947...79,015,256
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Abhd5 |
abhydrolase domain containing 5 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ABHD5 mRNA |
CTD |
PMID:14699072 |
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NCBI chr 9:122,180,681...122,210,589
Ensembl chr 9:122,180,673...122,210,589
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Abhd8 |
abhydrolase domain containing 8 |
affects response to substance |
ISO |
ABHD8 affects the susceptibility to Raloxifene Hydrochloride |
CTD |
PMID:32934756 |
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NCBI chr 8:71,909,344...71,917,351
Ensembl chr 8:71,909,349...71,916,299
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Ablim3 |
actin binding LIM protein family, member 3 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ABLIM3 mRNA |
CTD |
PMID:14699072 |
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NCBI chr18:61,932,463...62,044,956
Ensembl chr18:61,932,463...62,044,895
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Acan |
aggrecan |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Decitabine results in decreased expression of ACAN mRNA] |
CTD |
PMID:23385821 |
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NCBI chr 7:78,702,974...78,764,847
Ensembl chr 7:78,703,231...78,764,847
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Ace |
angiotensin I converting enzyme |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of ACE mRNA |
CTD |
PMID:15849065 |
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NCBI chr11:105,858,774...105,880,790
Ensembl chr11:105,858,771...105,880,790
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Ache |
acetylcholinesterase |
decreases activity |
ISO |
Raloxifene Hydrochloride results in decreased activity of ACHE protein |
CTD |
PMID:33844597 |
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NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728
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Ackr3 |
atypical chemokine receptor 3 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of ACKR3 mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ACKR3 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr 1:90,131,702...90,143,446
Ensembl chr 1:90,131,702...90,144,473
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Acsl1 |
acyl-CoA synthetase long-chain family member 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ACSL1 mRNA |
CTD |
PMID:19059307 |
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NCBI chr 8:46,924,214...46,989,088
Ensembl chr 8:46,924,074...46,989,088
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Acta2 |
actin alpha 2, smooth muscle, aorta |
multiple interactions |
EXP |
Raloxifene Hydrochloride affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of ACTA2 protein] |
CTD |
PMID:32828944 |
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NCBI chr19:34,217,736...34,232,985
Ensembl chr19:34,218,490...34,232,990
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Acvrl1 |
activin A receptor, type II-like 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of ACVRL1 mRNA; Raloxifene Hydrochloride results in increased expression of ACVRL1 protein |
CTD |
PMID:20135064 |
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NCBI chr15:101,026,403...101,043,217
Ensembl chr15:101,026,403...101,043,217
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Adam19 |
ADAM metallopeptidase domain 19 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ADAM19 mRNA |
CTD |
PMID:19059307 |
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NCBI chr11:45,945,329...46,038,174
Ensembl chr11:45,946,819...46,038,170
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Adam22 |
a disintegrin and metallopeptidase domain 22 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of ADAM22 mRNA |
CTD |
PMID:19429434 |
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NCBI chr 5:8,122,353...8,418,312
Ensembl chr 5:8,122,352...8,418,160
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Adamtsl3 |
ADAMTS-like 3 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ADAMTSL3 mRNA |
CTD |
PMID:14699072 |
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NCBI chr 7:81,984,612...82,263,658
Ensembl chr 7:81,984,902...82,263,658
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Adcy2 |
adenylate cyclase 2 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ADCY2 mRNA |
CTD |
PMID:16079270 |
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NCBI chr13:68,768,162...69,147,719
Ensembl chr13:68,768,162...69,147,660
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Adcyap1 |
adenylate cyclase activating polypeptide 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ADCYAP1 mRNA |
CTD |
PMID:16079270 |
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NCBI chr17:93,506,448...93,513,967
Ensembl chr17:93,506,445...93,513,965
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Adgra3 |
adhesion G protein-coupled receptor A3 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of ADGRA3 mRNA |
CTD |
PMID:19429434 |
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NCBI chr 5:50,117,293...50,216,338
Ensembl chr 5:50,117,298...50,216,348
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Adgrb2 |
adhesion G protein-coupled receptor B2 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ADGRB2 mRNA |
CTD |
PMID:14699072 |
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NCBI chr 4:129,878,566...129,916,426
Ensembl chr 4:129,878,663...129,916,426
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Adgrg1 |
adhesion G protein-coupled receptor G1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ADGRG1 mRNA |
CTD |
PMID:14699072 |
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NCBI chr 8:95,701,321...95,740,836
Ensembl chr 8:95,701,379...95,740,845
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Adh1 |
alcohol dehydrogenase 1 (class I) |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of ADH1 mRNA |
CTD |
PMID:15576828 |
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NCBI chr 3:137,983,346...137,996,459
Ensembl chr 3:137,966,752...137,996,459
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Adipoq |
adiponectin, C1Q and collagen domain containing |
increases expression |
EXP |
Raloxifene Hydrochloride results in increased expression of ADIPOQ mRNA |
CTD |
PMID:16643890 |
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NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778
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Adora2a |
adenosine A2a receptor |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of ADORA2A mRNA |
CTD |
PMID:15849065 |
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NCBI chr10:75,152,711...75,170,626
Ensembl chr10:75,152,711...75,170,618
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Adora2b |
adenosine A2b receptor |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ADORA2B mRNA |
CTD |
PMID:19059307 |
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NCBI chr11:62,139,810...62,157,278
Ensembl chr11:62,139,810...62,157,279
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Adra1a |
adrenergic receptor, alpha 1a |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of ADRA1A mRNA |
CTD |
PMID:20201831 |
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NCBI chr14:66,872,705...67,009,549
Ensembl chr14:66,872,700...67,008,617
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Aebp1 |
AE binding protein 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of AEBP1 mRNA |
CTD |
PMID:15576828 |
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NCBI chr11:5,806,085...5,822,248
Ensembl chr11:5,811,947...5,822,088
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Ago2 |
argonaute RISC catalytic subunit 2 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of AGO2 mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of AGO2 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr15:72,967,693...73,056,777
Ensembl chr15:72,967,693...73,056,784
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Agt |
angiotensinogen |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with Estradiol] inhibits the reaction [AGT protein results in increased phosphorylation of STAT3 protein]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [[Raloxifene Hydrochloride co-treated with Estradiol] inhibits the reaction [AGT protein results in increased phosphorylation of STAT3 protein]] |
CTD |
PMID:17336289 |
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NCBI chr 8:125,283,326...125,296,445
Ensembl chr 8:125,283,273...125,296,445
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Ahcyl1 |
S-adenosylhomocysteine hydrolase-like 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of AHCYL1 mRNA |
CTD |
PMID:14699072 |
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NCBI chr 3:107,570,436...107,603,876
Ensembl chr 3:107,570,434...107,603,876
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Ahnak |
AHNAK nucleoprotein |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of AHNAK mRNA |
CTD |
PMID:16514628 |
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NCBI chr19:8,966,640...9,054,299
Ensembl chr19:8,966,648...9,054,278
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Ahr |
aryl-hydrocarbon receptor |
multiple interactions affects localization affects binding |
ISO EXP |
[Raloxifene Hydrochloride results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA Raloxifene Hydrochloride affects the localization of AHR protein Raloxifene Hydrochloride binds to AHR protein Raloxifene Hydrochloride inhibits the reaction [Methylcholanthrene binds to AHR protein] |
CTD |
PMID:19901195 PMID:24481452 |
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NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037
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Aimp1 |
aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of AIMP1 mRNA |
CTD |
PMID:12154049 |
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NCBI chr 3:132,366,259...132,390,151
Ensembl chr 3:132,366,242...132,390,131
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Ak3 |
adenylate kinase 3 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of AK3 mRNA |
CTD |
PMID:16079270 |
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NCBI chr19:28,968,715...29,026,122
Ensembl chr19:28,998,233...29,025,361
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Akap1 |
A kinase anchor protein 1 |
multiple interactions affects expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of AKAP1 mRNA Raloxifene Hydrochloride affects the expression of AKAP1 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr11:88,721,618...88,755,426
Ensembl chr11:88,721,618...88,755,412
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Akr7a5 |
aldo-keto reductase family 7, member A5 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of AKR7A2 mRNA |
CTD |
PMID:16079270 |
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NCBI chr 4:139,038,005...139,046,097
Ensembl chr 4:139,038,055...139,045,737
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Akt1 |
thymoma viral proto-oncogene 1 |
decreases phosphorylation increases phosphorylation multiple interactions |
ISO |
Raloxifene Hydrochloride results in decreased phosphorylation of AKT1 protein Raloxifene Hydrochloride results in increased phosphorylation of AKT1 protein Raloxifene Hydrochloride inhibits the reaction [TGFA protein results in increased phosphorylation of AKT1 protein] |
CTD |
PMID:15590986 PMID:15876410 PMID:16798746 PMID:25537862 PMID:35007301 |
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NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318
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Alad |
aminolevulinate, delta-, dehydratase |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of ALAD mRNA |
CTD |
PMID:26865669 |
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NCBI chr 4:62,422,762...62,438,300
Ensembl chr 4:62,427,406...62,438,155
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Alas2 |
aminolevulinic acid synthase 2, erythroid |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ALAS2 mRNA |
CTD |
PMID:16079270 |
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NCBI chr X:149,330,443...149,353,614
Ensembl chr X:149,330,371...149,353,634
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Alcam |
activated leukocyte cell adhesion molecule |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in decreased expression of ALCAM mRNA] |
CTD |
PMID:21185374 |
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NCBI chr16:52,069,359...52,273,444
Ensembl chr16:52,069,359...52,274,437
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Alox5 |
arachidonate 5-lipoxygenase |
multiple interactions |
EXP |
[APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of ALOX5 mRNA |
CTD |
PMID:24431404 |
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NCBI chr 6:116,387,030...116,438,139
Ensembl chr 6:116,387,038...116,438,139
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Alpl |
alkaline phosphatase, liver/bone/kidney |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Decitabine results in increased expression of ALPL mRNA] |
CTD |
PMID:23385821 |
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NCBI chr 4:137,469,042...137,523,695
Ensembl chr 4:137,469,044...137,523,695
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Amigo2 |
adhesion molecule with Ig like domain 2 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of AMIGO2 mRNA |
CTD |
PMID:19059307 |
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NCBI chr15:97,141,955...97,145,168
Ensembl chr15:97,142,006...97,145,168
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Amotl2 |
angiomotin-like 2 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of AMOTL2 mRNA |
CTD |
PMID:14699072 |
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NCBI chr 9:102,594,290...102,610,616
Ensembl chr 9:102,593,871...102,610,617
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Ang |
angiogenin, ribonuclease, RNase A family, 5 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of ANG mRNA |
CTD |
PMID:19429434 |
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NCBI chr14:51,328,607...51,339,462
Ensembl chr14:51,328,607...51,339,466
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Angptl2 |
angiopoietin-like 2 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ANGPTL2 mRNA |
CTD |
PMID:14699072 |
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NCBI chr 2:33,105,963...33,137,737
Ensembl chr 2:33,106,081...33,137,729
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Angptl7 |
angiopoietin-like 7 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of ANGPTL7 mRNA |
CTD |
PMID:16202921 |
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NCBI chr 4:148,579,737...148,584,919
Ensembl chr 4:148,579,640...148,584,917
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Ank3 |
ankyrin 3, epithelial |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ANK3 mRNA |
CTD |
PMID:16079270 |
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NCBI chr10:69,234,608...69,863,266
Ensembl chr10:69,234,603...69,863,268
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Ankrd1 |
ankyrin repeat domain 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ANKRD1 mRNA |
CTD |
PMID:19059307 |
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NCBI chr19:36,089,365...36,097,244
Ensembl chr19:36,089,361...36,097,499
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Ankrd28 |
ankyrin repeat domain 28 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of ANKRD28 mRNA |
CTD |
PMID:19059307 |
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NCBI chr14:31,418,687...31,552,374
Ensembl chr14:31,420,725...31,552,608
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Aopep |
aminopeptidase O |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with Estradiol] results in increased expression of AOPEP mRNA |
CTD |
PMID:21185374 |
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NCBI chr13:63,112,707...63,473,910
Ensembl chr13:63,112,707...63,473,910
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Aox1 |
aldehyde oxidase 1 |
multiple interactions decreases activity |
ISO |
Raloxifene Hydrochloride inhibits the reaction [AOX1 protein results in increased metabolism of zoniporide] Raloxifene Hydrochloride results in decreased activity of AOX1 protein |
CTD |
PMID:20040581 |
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NCBI chr 1:58,068,963...58,145,569
Ensembl chr 1:58,069,090...58,145,572
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Ap1g1 |
adaptor protein complex AP-1, gamma 1 subunit |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of AP1G1 mRNA |
CTD |
PMID:14699072 |
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NCBI chr 8:110,505,215...110,590,842
Ensembl chr 8:110,505,186...110,590,836
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Apc |
APC, WNT signaling pathway regulator |
affects response to substance multiple interactions |
EXP |
APC protein affects the susceptibility to Raloxifene Hydrochloride [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of ALOX5 mRNA; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of CCL6 mRNA; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of CCND1 mRNA; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of CD24 mRNA; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of CD24 protein; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of CD44 mRNA; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of CD44 protein; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of CTNNB1 mRNA; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of EPCAM mRNA; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of EPCAM protein; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of ESR2 protein; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of LAMB1 mRNA; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of LGR5 mRNA; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of LGR5 protein; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of PCNA protein; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of PTGES mRNA; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of PTGS2 mRNA; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of PTGS2 protein |
CTD |
PMID:24431404 |
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NCBI chr18:34,353,350...34,455,243
Ensembl chr18:34,353,977...34,455,605
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Apex1 |
apurinic/apyrimidinic endonuclease 1 |
multiple interactions increases expression |
ISO |
[Raloxifene Hydrochloride co-treated with Kainic Acid] results in increased expression of APEX1 mRNA Raloxifene Hydrochloride results in increased expression of APEX1 mRNA |
CTD |
PMID:16120186 |
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NCBI chr14:51,162,406...51,164,645
Ensembl chr14:51,162,425...51,164,596
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G |
Apod |
apolipoprotein D |
increases expression multiple interactions |
ISO |
Raloxifene Hydrochloride results in increased expression of APOD mRNA Raloxifene Hydrochloride inhibits the reaction [Estradiol results in decreased expression of APOD protein] |
CTD |
PMID:16514628 PMID:27163517 |
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NCBI chr16:31,115,010...31,133,626
Ensembl chr16:31,115,010...31,133,626
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G |
Apoe |
apolipoprotein E |
multiple interactions |
EXP |
Raloxifene Hydrochloride affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of ACTA2 protein]; Raloxifene Hydrochloride affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of CD68 protein]; Raloxifene Hydrochloride affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of ICAM1 protein]; Raloxifene Hydrochloride affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of IL6 protein]; Raloxifene Hydrochloride affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of VCAM1 protein]; Raloxifene Hydrochloride affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the phosphorylation of STAT3 protein]; Raloxifene Hydrochloride affects the reaction [[APOE protein affects the susceptibility to IL6 protein] which affects the phosphorylation of STAT3 protein] |
CTD |
PMID:32828944 |
|
NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113
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G |
App |
amyloid beta precursor protein |
affects binding multiple interactions |
ISO |
Raloxifene Hydrochloride binds to APP protein Raloxifene Hydrochloride inhibits the reaction [APP protein results in increased expression of TGFB1 mRNA]; Raloxifene Hydrochloride inhibits the reaction [APP protein results in increased expression of TNF mRNA] |
CTD |
PMID:31583774 |
|
NCBI chr16:84,751,236...84,972,187
Ensembl chr16:84,746,573...84,970,654
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G |
Ar |
androgen receptor |
decreases expression multiple interactions affects expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of AR mRNA; Raloxifene Hydrochloride results in decreased expression of AR protein [Raloxifene Hydrochloride co-treated with Estradiol] results in decreased expression of AR protein Raloxifene Hydrochloride affects the expression of AR mRNA |
CTD |
PMID:11867264 PMID:15731164 PMID:16837883 PMID:27163517 |
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NCBI chr X:97,192,363...97,366,824
Ensembl chr X:97,192,375...97,366,821
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G |
Areg |
amphiregulin |
multiple interactions decreases expression increases expression |
ISO EXP |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of AREG mRNA Raloxifene Hydrochloride results in decreased expression of AREG mRNA Raloxifene Hydrochloride inhibits the reaction [Estrogens, Conjugated (USP) results in increased expression of AREG mRNA] Raloxifene Hydrochloride results in increased expression of AREG mRNA |
CTD |
PMID:16514628 PMID:19022889 PMID:19059307 PMID:26865669 |
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NCBI chr 5:91,287,458...91,296,291
Ensembl chr 5:91,287,458...91,296,291
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G |
Arg2 |
arginase type II |
increases expression |
EXP |
Raloxifene Hydrochloride results in increased expression of ARG2 mRNA |
CTD |
PMID:22841776 |
|
NCBI chr12:79,177,562...79,203,075
Ensembl chr12:79,177,551...79,203,075
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G |
Arhgap29 |
Rho GTPase activating protein 29 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ARHGAP29 mRNA |
CTD |
PMID:14699072 |
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NCBI chr 3:121,746,752...121,810,326
Ensembl chr 3:121,746,190...121,810,402
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G |
Arid5a |
AT-rich interaction domain 5A |
multiple interactions |
ISO |
ARID5A protein inhibits the reaction [Raloxifene Hydrochloride results in increased activity of ESR1 protein] |
CTD |
PMID:15941852 |
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NCBI chr 1:36,346,814...36,363,117
Ensembl chr 1:36,346,814...36,363,110
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G |
Arid5b |
AT-rich interaction domain 5B |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ARID5B mRNA |
CTD |
PMID:14699072 |
|
NCBI chr10:67,928,353...68,114,596
Ensembl chr10:67,928,350...68,114,570
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G |
Arl1 |
ADP-ribosylation factor-like 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ARL1 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr10:88,566,720...88,579,956
Ensembl chr10:88,566,720...88,579,956
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G |
Arl4c |
ADP-ribosylation factor-like 4C |
multiple interactions affects expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ARL4C mRNA Raloxifene Hydrochloride affects the expression of ARL4C mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr 1:88,625,947...88,629,913
Ensembl chr 1:88,600,847...88,629,943
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G |
Arnt |
aryl hydrocarbon receptor nuclear translocator |
multiple interactions |
EXP |
ARNT protein affects the reaction [Raloxifene Hydrochloride results in increased expression of CYP1A1 protein]; ARNT protein affects the reaction [Raloxifene Hydrochloride results in increased expression of NQO1 protein] |
CTD |
PMID:24481452 |
|
NCBI chr 3:95,341,674...95,404,551
Ensembl chr 3:95,341,699...95,404,551
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G |
Arnt2 |
aryl hydrocarbon receptor nuclear translocator 2 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of ARNT2 mRNA |
CTD |
PMID:16514628 |
|
NCBI chr 7:83,895,486...84,059,201
Ensembl chr 7:83,895,486...84,059,384
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G |
Asb13 |
ankyrin repeat and SOCS box-containing 13 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ASB13 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr13:3,683,589...3,703,822
Ensembl chr13:3,684,032...3,703,822
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G |
Asns |
asparagine synthetase |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of ASNS mRNA |
CTD |
PMID:16514628 |
|
NCBI chr 6:7,675,169...7,693,209
Ensembl chr 6:7,675,169...7,693,254
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G |
Atf3 |
activating transcription factor 3 |
multiple interactions increases expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ATF3 mRNA Raloxifene Hydrochloride results in increased expression of ATF3 mRNA |
CTD |
PMID:16497877 PMID:19059307 |
|
NCBI chr 1:190,902,493...190,915,530
Ensembl chr 1:190,902,493...190,950,236
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G |
Atf7ip |
activating transcription factor 7 interacting protein |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of ATF7IP mRNA |
CTD |
PMID:19429434 |
|
NCBI chr 6:136,495,787...136,587,848
Ensembl chr 6:136,483,165...136,587,860
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G |
Atg12 |
autophagy related 12 |
multiple interactions |
ISO |
Raloxifene Hydrochloride promotes the reaction [ATG12 protein binds to ATG5 protein] |
CTD |
PMID:25537862 |
|
NCBI chr18:46,865,484...46,874,683
Ensembl chr18:46,863,211...46,874,647
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G |
Atg5 |
autophagy related 5 |
multiple interactions |
ISO |
Raloxifene Hydrochloride promotes the reaction [ATG12 protein binds to ATG5 protein] |
CTD |
PMID:25537862 |
|
NCBI chr10:44,144,325...44,240,295
Ensembl chr10:44,144,354...44,240,287
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G |
Atp1a1 |
ATPase, Na+/K+ transporting, alpha 1 polypeptide |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ATP1A1 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 3:101,483,535...101,512,023
Ensembl chr 3:101,483,535...101,512,000
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G |
Atp9a |
ATPase, class II, type 9A |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ATP9A mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 2:168,476,358...168,584,290
Ensembl chr 2:168,476,358...168,584,329
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G |
Atxn3 |
ataxin 3 |
increases expression |
EXP |
Raloxifene Hydrochloride results in increased expression of ATXN3 mRNA |
CTD |
PMID:33269387 |
|
NCBI chr12:101,885,160...101,928,139
Ensembl chr12:101,885,160...101,924,505
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G |
Aurka |
aurora kinase A |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of AURKA mRNA |
CTD |
PMID:16514628 |
|
NCBI chr 2:172,198,116...172,212,825
Ensembl chr 2:172,198,110...172,212,455
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G |
Avp |
arginine vasopressin |
multiple interactions decreases expression |
ISO |
4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [Raloxifene Hydrochloride results in decreased expression of AVP mRNA]; GPER1 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of AVP mRNA]; sotrastaurin inhibits the reaction [Raloxifene Hydrochloride results in decreased expression of AVP mRNA]; U 0126 inhibits the reaction [Raloxifene Hydrochloride results in decreased expression of AVP mRNA] |
CTD |
PMID:26200092 |
|
NCBI chr 2:130,422,540...130,424,508
Ensembl chr 2:130,422,540...130,424,474
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G |
Axin2 |
axin 2 |
decreases expression multiple interactions |
ISO |
Raloxifene Hydrochloride results in decreased expression of AXIN2 mRNA [Raloxifene Hydrochloride co-treated with PX-866] results in decreased expression of AXIN2 mRNA |
CTD |
PMID:27017931 |
|
NCBI chr11:108,808,687...108,841,609
Ensembl chr11:108,811,175...108,841,609
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G |
Bad |
BCL2-associated agonist of cell death |
increases cleavage |
ISO |
Raloxifene Hydrochloride results in increased cleavage of BAD protein |
CTD |
PMID:12084714 |
|
NCBI chr19:6,919,229...6,929,273
Ensembl chr19:6,919,229...6,929,267
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G |
Bak1 |
BCL2-antagonist/killer 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of BAK1 mRNA |
CTD |
PMID:16202921 |
|
NCBI chr17:27,238,786...27,247,601
Ensembl chr17:27,238,784...27,247,983
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G |
Bap1 |
Brca1 associated protein 1 |
multiple interactions |
EXP |
[SOD1 protein mutant form affects the susceptibility to Raloxifene Hydrochloride] which results in decreased expression of BAP1 mRNA |
CTD |
PMID:33269387 |
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NCBI chr14:30,973,358...30,981,887
Ensembl chr14:30,973,407...30,981,901
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G |
Bax |
BCL2-associated X protein |
affects expression increases expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of BAX protein Raloxifene Hydrochloride results in increased expression of BAX mRNA [Raloxifene Hydrochloride co-treated with Resveratrol] results in increased expression of BAX mRNA |
CTD |
PMID:16009171 PMID:29705353 |
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NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
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G |
Bcas1 |
brain enriched myelin associated protein 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with Estradiol] results in increased expression of BCAS1 mRNA |
CTD |
PMID:21185374 |
|
NCBI chr 2:170,188,911...170,270,292
Ensembl chr 2:170,188,911...170,269,765
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G |
Bcl2 |
B cell leukemia/lymphoma 2 |
affects expression decreases expression increases expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of BCL2 protein Raloxifene Hydrochloride results in decreased expression of BCL2 mRNA; Raloxifene Hydrochloride results in decreased expression of BCL2 protein Raloxifene Hydrochloride results in increased expression of BCL2 protein [Resveratrol co-treated with Raloxifene Hydrochloride] results in decreased expression of BCL2 mRNA |
CTD |
PMID:16009171 PMID:16566921 PMID:16973256 PMID:17220163 PMID:20945400 PMID:28430601 PMID:29705353 More...
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NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
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G |
Bcl2l1 |
BCL2-like 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of BCL2L1 protein |
CTD |
PMID:28430601 |
|
NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648
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G |
Bcl2l11 |
BCL2 like 11 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of BCL2L11 mRNA |
CTD |
PMID:19429434 |
|
NCBI chr 2:127,967,958...128,004,467
Ensembl chr 2:127,967,958...128,004,467
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G |
Bcl3 |
B cell leukemia/lymphoma 3 |
multiple interactions |
EXP |
Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased expression of BCL3 mRNA] |
CTD |
PMID:12072388 |
|
NCBI chr 7:19,542,387...19,556,691
Ensembl chr 7:19,542,387...19,556,695
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G |
Bcl6 |
B cell leukemia/lymphoma 6 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of BCL6 mRNA |
CTD |
PMID:16497877 |
|
NCBI chr16:23,780,058...23,807,602
Ensembl chr16:23,783,802...23,807,602
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G |
Becn1 |
beclin 1, autophagy related |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of BECN1 protein |
CTD |
PMID:25537862 |
|
NCBI chr11:101,179,084...101,193,112
Ensembl chr11:101,176,778...101,193,112
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G |
Bglap |
bone gamma carboxyglutamate protein |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of BGLAP protein |
CTD |
PMID:17823083 |
|
NCBI chr 3:88,290,802...88,291,773
Ensembl chr 3:88,290,808...88,291,771
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G |
Bgn |
biglycan |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of BGN mRNA |
CTD |
PMID:15576828 PMID:19429434 |
|
NCBI chr X:72,527,207...72,539,542
Ensembl chr X:72,527,208...72,539,539
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G |
Bhlhe40 |
basic helix-loop-helix family, member e40 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with PX-866] results in increased expression of BHLHE40 mRNA |
CTD |
PMID:27017931 |
|
NCBI chr 6:108,637,590...108,643,886
Ensembl chr 6:108,637,590...108,643,886
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G |
Birc3 |
baculoviral IAP repeat-containing 3 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of BIRC3 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 9:7,848,698...7,873,199
Ensembl chr 9:7,848,700...7,873,187
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G |
Birc5 |
baculoviral IAP repeat-containing 5 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of BIRC5 protein |
CTD |
PMID:28430601 |
|
NCBI chr11:117,740,063...117,746,569
Ensembl chr11:117,740,077...117,746,569
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G |
Blzf1 |
basic leucine zipper nuclear factor 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of BLZF1 mRNA |
CTD |
PMID:19429434 |
|
NCBI chr 1:164,117,368...164,135,056
Ensembl chr 1:164,117,369...164,135,058
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G |
Bmp7 |
bone morphogenetic protein 7 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of BMP7 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 2:172,709,805...172,782,114
Ensembl chr 2:172,709,805...172,782,114
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G |
Brinp2 |
bone morphogenic protein/retinoic acid inducible neural-specific 2 |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of BRINP2 mRNA] |
CTD |
PMID:21185374 |
|
NCBI chr 1:158,072,835...158,185,096
Ensembl chr 1:158,072,839...158,183,896
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G |
Btg2 |
BTG anti-proliferation factor 2 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of BTG2 mRNA |
CTD |
PMID:22965848 |
|
NCBI chr 1:134,002,603...134,006,893
Ensembl chr 1:134,002,908...134,006,858
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G |
C1qb |
complement component 1, q subcomponent, beta polypeptide |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of C1QB mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 4:136,607,437...136,613,511
Ensembl chr 4:136,607,440...136,613,498
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G |
C2cd2 |
C2 calcium-dependent domain containing 2 |
multiple interactions affects expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of C2CD2 mRNA Raloxifene Hydrochloride affects the expression of C2CD2 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr16:97,656,409...97,727,248
Ensembl chr16:97,656,409...97,763,798
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G |
C3 |
complement component 3 |
increases expression |
EXP |
Raloxifene Hydrochloride results in increased expression of C3 mRNA |
CTD |
PMID:12370124 |
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NCBI chr17:57,510,967...57,535,136
Ensembl chr17:57,510,970...57,535,136
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G |
Cabin1 |
calcineurin binding protein 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CABIN1 mRNA |
CTD |
PMID:15576828 |
|
NCBI chr10:75,481,944...75,600,194
Ensembl chr10:75,481,946...75,600,175
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G |
Cacna1h |
calcium channel, voltage-dependent, T type, alpha 1H subunit |
decreases expression |
EXP |
Raloxifene Hydrochloride results in decreased expression of CACNA1H mRNA |
CTD |
PMID:21228613 |
|
NCBI chr17:25,593,259...25,655,308
Ensembl chr17:25,593,259...25,652,759
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G |
Cacna1i |
calcium channel, voltage-dependent, alpha 1I subunit |
decreases expression |
EXP |
Raloxifene Hydrochloride results in decreased expression of CACNA1I mRNA |
CTD |
PMID:21228613 |
|
NCBI chr15:80,171,439...80,282,493
Ensembl chr15:80,171,439...80,282,480
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G |
Calb2 |
calbindin 2 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CALB2 mRNA |
CTD |
PMID:17962382 |
|
NCBI chr 8:110,869,158...110,894,844
Ensembl chr 8:110,864,134...110,894,842
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G |
Cald1 |
caldesmon 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of CALD1 mRNA |
CTD |
PMID:19429434 |
|
NCBI chr 6:34,575,433...34,752,404
Ensembl chr 6:34,575,435...34,752,408
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G |
Calm1 |
calmodulin 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CALM1 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr12:100,165,694...100,176,083
Ensembl chr12:100,165,694...100,176,073
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G |
Cap2 |
cyclase associated actin cytoskeleton regulatory protein 2 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of CAP2 mRNA |
CTD |
PMID:15576828 |
|
NCBI chr13:46,655,379...46,803,757
Ensembl chr13:46,655,324...46,803,757
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G |
Capn2 |
calpain 2 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of CAPN2 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 1:182,294,818...182,345,175
Ensembl chr 1:182,294,825...182,345,173
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G |
Car12 |
carbonic anhydrase 12 |
affects expression multiple interactions decreases expression |
ISO |
Raloxifene Hydrochloride affects the expression of CA12 mRNA [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of CA12 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CA12 mRNA Raloxifene Hydrochloride results in decreased expression of CA12 mRNA |
CTD |
PMID:14699072 PMID:19059307 PMID:26865669 |
|
NCBI chr 9:66,619,026...66,674,127
Ensembl chr 9:66,620,968...66,674,127
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G |
Car4 |
carbonic anhydrase 4 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of CA4 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr11:84,848,580...84,856,880
Ensembl chr11:84,848,612...84,856,870
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G |
Card10 |
caspase recruitment domain family, member 10 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of CARD10 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr15:78,659,323...78,687,261
Ensembl chr15:78,659,338...78,687,242
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|
G |
Caskin2 |
CASK-interacting protein 2 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CASKIN2 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr11:115,689,813...115,704,517
Ensembl chr11:115,690,009...115,704,465
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G |
Casp3 |
caspase 3 |
increases expression multiple interactions increases cleavage decreases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CASP3 mRNA; Raloxifene Hydrochloride results in increased expression of CASP3 protein modified form [Resveratrol co-treated with Raloxifene Hydrochloride] results in decreased expression of CASP3 mRNA; STAT3 protein affects the reaction [Raloxifene Hydrochloride results in increased cleavage of CASP3 protein] Raloxifene Hydrochloride inhibits the reaction [Decitabine results in increased activity of CASP3 protein] Raloxifene Hydrochloride results in decreased expression of CASP3 mRNA; Raloxifene Hydrochloride results in decreased expression of CASP3 protein |
CTD |
PMID:20945400 PMID:22965848 PMID:23385821 PMID:27999800 PMID:28430601 PMID:28711499 PMID:29705353 More...
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NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
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G |
Casp4 |
caspase 4, apoptosis-related cysteine peptidase |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CASP4 mRNA |
CTD |
PMID:12154049 |
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NCBI chr 9:5,308,816...5,336,791
Ensembl chr 9:5,308,828...5,336,783
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G |
Casp7 |
caspase 7 |
multiple interactions affects expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CASP7 mRNA Raloxifene Hydrochloride affects the expression of CASP7 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr19:56,382,640...56,430,780
Ensembl chr19:56,385,561...56,430,776
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G |
Casp8 |
caspase 8 |
decreases expression multiple interactions increases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of CASP8 mRNA; Raloxifene Hydrochloride results in decreased expression of CASP8 protein [Resveratrol co-treated with Raloxifene Hydrochloride] results in decreased expression of CASP8 mRNA Raloxifene Hydrochloride results in increased expression of CASP8 mRNA |
CTD |
PMID:27999800 PMID:29705353 |
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NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662
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G |
Cat |
catalase |
increases activity |
ISO |
Raloxifene Hydrochloride results in increased activity of CAT protein |
CTD |
PMID:17227729 |
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NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
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G |
Cav1 |
caveolin 1, caveolae protein |
affects expression multiple interactions increases expression |
ISO |
Raloxifene Hydrochloride affects the expression of CAV1 mRNA fulvestrant inhibits the reaction [Raloxifene Hydrochloride results in increased expression of CAV1 mRNA]; fulvestrant inhibits the reaction [Raloxifene Hydrochloride results in increased expression of CAV1 protein] Raloxifene Hydrochloride results in increased expression of CAV1 mRNA; Raloxifene Hydrochloride results in increased expression of CAV1 protein |
CTD |
PMID:14699072 PMID:17091190 |
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NCBI chr 6:17,306,387...17,341,323
Ensembl chr 6:17,306,334...17,341,451
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G |
Cbx1 |
chromobox 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of CBX1 mRNA |
CTD |
PMID:16514628 |
|
NCBI chr11:96,679,506...96,699,808
Ensembl chr11:96,679,953...96,699,466
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G |
Cbx3 |
chromobox 3 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of CBX3 mRNA |
CTD |
PMID:19429434 |
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NCBI chr 6:51,447,596...51,460,684
Ensembl chr 6:51,447,340...51,460,684
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
multiple interactions affects expression decreases activity |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CCL2 mRNA; fulvestrant inhibits the reaction [Raloxifene Hydrochloride results in decreased activity of CCL2 protein] Raloxifene Hydrochloride affects the expression of CCL2 mRNA Raloxifene Hydrochloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of CCL2 mRNA] |
CTD |
PMID:14699072 PMID:17006379 PMID:19059307 PMID:25305410 |
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NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
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G |
Ccl20 |
C-C motif chemokine ligand 20 |
affects expression multiple interactions |
ISO EXP |
Raloxifene Hydrochloride affects the expression of CCL20 mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CCL20 mRNA Fulvestrant inhibits the reaction [Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased expression of CCL20 protein]]; Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased expression of CCL20 protein] |
CTD |
PMID:14699072 PMID:19059307 PMID:24722370 |
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NCBI chr 1:83,094,487...83,096,888
Ensembl chr 1:83,094,487...83,096,888
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G |
Ccl3 |
C-C motif chemokine ligand 3 |
multiple interactions decreases expression |
ISO |
Raloxifene Hydrochloride inhibits the reaction [ESR1 protein binds to CCL3 promoter]; Raloxifene Hydrochloride inhibits the reaction [RELA protein binds to CCL3 promoter] Raloxifene Hydrochloride results in decreased expression of CCL3 mRNA |
CTD |
PMID:16497877 |
|
NCBI chr11:83,538,669...83,540,204
Ensembl chr11:83,538,670...83,540,181
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G |
Ccl5 |
C-C motif chemokine ligand 5 |
increases expression decreases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CCL5 mRNA Raloxifene Hydrochloride results in decreased expression of CCL5 protein |
CTD |
PMID:12154049 PMID:16842799 |
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NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344
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G |
Ccl6 |
C-C motif chemokine ligand 6 |
multiple interactions |
EXP |
[APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of CCL6 mRNA |
CTD |
PMID:24431404 |
|
NCBI chr11:83,478,712...83,483,913
Ensembl chr11:83,478,708...83,483,913
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G |
Ccn3 |
cellular communication network factor 3 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of CCN3 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr15:54,609,306...54,617,158
Ensembl chr15:54,609,098...54,617,435
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G |
Ccna2 |
cyclin A2 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CCNA2 mRNA; Raloxifene Hydrochloride results in increased expression of CCNA2 protein |
CTD |
PMID:17445807 |
|
NCBI chr 3:36,619,014...36,627,187
Ensembl chr 3:36,619,014...36,626,299
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G |
Ccnb1 |
cyclin B1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CCNB1 mRNA; Raloxifene Hydrochloride results in increased expression of CCNB1 protein |
CTD |
PMID:12154049 PMID:17445807 |
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NCBI chr13:100,915,247...100,922,994
Ensembl chr13:100,915,158...100,923,078
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G |
Ccnd1 |
cyclin D1 |
multiple interactions affects expression decreases expression |
ISO EXP |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CCND1 mRNA; [Raloxifene Hydrochloride co-treated with PX-866] results in decreased expression of CCND1 mRNA Raloxifene Hydrochloride affects the expression of CCND1 mRNA Raloxifene Hydrochloride results in decreased expression of CCND1 mRNA [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of CCND1 mRNA [Raloxifene Hydrochloride co-treated with Bexarotene] affects the reaction [Azoxymethane affects the expression of CCND1 mRNA]; [Raloxifene Hydrochloride co-treated with Bexarotene] affects the reaction [Azoxymethane affects the expression of CCND1 protein]; Raloxifene Hydrochloride affects the reaction [Azoxymethane affects the expression of CCND1 mRNA]; Raloxifene Hydrochloride affects the reaction [Azoxymethane affects the expression of CCND1 protein] |
CTD |
PMID:14699072 PMID:19059307 PMID:22965848 PMID:24080207 PMID:24431404 PMID:26865669 PMID:27017931 More...
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NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662
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G |
Ccne2 |
cyclin E2 |
multiple interactions decreases expression |
ISO |
[Raloxifene Hydrochloride co-treated with PX-866] results in decreased expression of CCNE2 mRNA Raloxifene Hydrochloride results in decreased expression of CCNE2 protein |
CTD |
PMID:26660119 |
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NCBI chr 4:11,190,489...11,204,781
Ensembl chr 4:11,191,351...11,204,779
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G |
Ccng2 |
cyclin G2 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CCNG2 mRNA |
CTD |
PMID:16497877 PMID:26865669 |
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NCBI chr 5:93,415,432...93,424,090
Ensembl chr 5:93,415,116...93,424,090
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G |
Cd200 |
CD200 molecule |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of CD200 mRNA |
CTD |
PMID:15576828 |
|
NCBI chr16:45,202,474...45,229,419
Ensembl chr16:45,202,498...45,229,416
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G |
Cd24a |
CD24a antigen |
increases expression multiple interactions |
ISO EXP |
Raloxifene Hydrochloride results in increased expression of CD24 mRNA [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of CD24 mRNA; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of CD24 protein |
CTD |
PMID:16514628 PMID:24431404 |
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NCBI chr10:43,454,433...43,460,261
Ensembl chr10:43,454,280...43,460,261
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G |
Cd3g |
CD3 antigen, gamma polypeptide |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of CD3G mRNA |
CTD |
PMID:16079270 |
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NCBI chr 9:44,880,870...44,891,729
Ensembl chr 9:44,880,870...44,891,729
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G |
Cd40 |
CD40 antigen |
multiple interactions |
EXP |
Raloxifene Hydrochloride inhibits the reaction [Lipopolysaccharides results in increased expression of CD40 protein] |
CTD |
PMID:16081843 |
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NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868
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G |
Cd44 |
CD44 antigen |
decreases expression multiple interactions |
ISO EXP |
Raloxifene Hydrochloride results in decreased expression of CD44 mRNA [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of CD44 mRNA; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of CD44 protein |
CTD |
PMID:24431404 PMID:26865669 |
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NCBI chr 2:102,641,486...102,732,014
Ensembl chr 2:102,641,486...102,732,010
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G |
Cd52 |
CD52 antigen |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of CD52 mRNA |
CTD |
PMID:16079270 |
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NCBI chr 4:133,820,849...133,822,384
Ensembl chr 4:133,809,759...133,822,393
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G |
Cd68 |
CD68 antigen |
multiple interactions |
EXP |
Raloxifene Hydrochloride affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of CD68 protein] |
CTD |
PMID:32828944 |
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NCBI chr11:69,555,039...69,556,996
Ensembl chr11:69,555,039...69,556,979
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G |
Cd74 |
CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of CD74 mRNA |
CTD |
PMID:16079270 |
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NCBI chr18:60,936,921...60,945,724
Ensembl chr18:60,936,920...60,945,724
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G |
Cd80 |
CD80 antigen |
multiple interactions |
EXP |
Raloxifene Hydrochloride inhibits the reaction [Lipopolysaccharides results in increased expression of CD80 protein] |
CTD |
PMID:16081843 |
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NCBI chr16:38,277,793...38,316,682
Ensembl chr16:38,275,923...38,316,697
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G |
Cd86 |
CD86 antigen |
multiple interactions |
EXP |
Raloxifene Hydrochloride inhibits the reaction [Lipopolysaccharides results in increased expression of CD86 protein] |
CTD |
PMID:16081843 |
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NCBI chr16:36,389,318...36,486,439
Ensembl chr16:36,424,231...36,486,443
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G |
Cd8a |
CD8 subunit alpha |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of CD8A mRNA |
CTD |
PMID:16079270 |
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NCBI chr 6:71,350,411...71,356,155
Ensembl chr 6:71,350,411...71,356,157
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G |
Cdc6 |
cell division cycle 6 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with PX-866] results in decreased expression of CDC6 mRNA |
CTD |
PMID:26660119 |
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NCBI chr11:98,798,627...98,814,768
Ensembl chr11:98,798,627...98,814,766
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G |
Cdh2 |
cadherin 2 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of CDH2 mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CDH2 mRNA |
CTD |
PMID:14699072 PMID:16079270 PMID:19059307 |
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NCBI chr18:16,721,934...16,942,303
Ensembl chr18:16,721,934...16,942,303
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G |
Cdh6 |
cadherin 6 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of CDH6 mRNA |
CTD |
PMID:16079270 |
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NCBI chr15:13,028,785...13,176,493
Ensembl chr15:13,028,787...13,173,761
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G |
Cdk1 |
cyclin dependent kinase 1 |
multiple interactions |
ISO |
Raloxifene Hydrochloride promotes the reaction [Estradiol results in increased expression of CDK1 mRNA]; trichostatin A inhibits the reaction [Raloxifene Hydrochloride promotes the reaction [Estradiol results in increased expression of CDK1 mRNA]] |
CTD |
PMID:22476901 |
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NCBI chr10:69,170,976...69,188,742
Ensembl chr10:69,170,976...69,188,768
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G |
Cdk2 |
cyclin dependent kinase 2 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with Bexarotene] affects the reaction [Azoxymethane affects the expression of CDK2 protein] |
CTD |
PMID:24080207 |
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NCBI chr10:128,533,807...128,540,920
Ensembl chr10:128,533,808...128,540,900
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G |
Cdk5r1 |
cyclin dependent kinase 5, regulatory subunit 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CDK5R1 mRNA |
CTD |
PMID:19059307 |
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NCBI chr11:80,367,849...80,372,010
Ensembl chr11:80,367,849...80,372,010
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G |
Cdk5rap3 |
CDK5 regulatory subunit associated protein 3 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of CDK5RAP3 mRNA |
CTD |
PMID:16079270 |
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NCBI chr11:96,798,251...96,807,359
Ensembl chr11:96,798,252...96,807,322
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G |
Cdkn1a |
cyclin dependent kinase inhibitor 1A |
increases expression multiple interactions |
ISO |
Raloxifene Hydrochloride results in increased expression of CDKN1A mRNA; Raloxifene Hydrochloride results in increased expression of CDKN1A protein [Raloxifene Hydrochloride co-treated with PX-866] results in increased expression of CDKN1A mRNA [Raloxifene Hydrochloride co-treated with Bexarotene] affects the reaction [Azoxymethane affects the expression of CDKN1A protein] |
CTD |
PMID:12154049 PMID:16497877 PMID:24080207 PMID:27017931 |
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NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701
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G |
Cdkn1b |
cyclin dependent kinase inhibitor 1B |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CDKN1B protein |
CTD |
PMID:16536755 PMID:22965848 |
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NCBI chr 6:134,897,364...134,902,488
Ensembl chr 6:134,897,364...134,902,476
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G |
Cdo1 |
cysteine dioxygenase 1, cytosolic |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CDO1 mRNA |
CTD |
PMID:19059307 |
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NCBI chr18:46,846,260...46,861,569
Ensembl chr18:46,846,260...46,861,462
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G |
Cdon |
cell adhesion molecule-related/down-regulated by oncogenes |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of CDON mRNA |
CTD |
PMID:14699072 |
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NCBI chr 9:35,332,836...35,418,948
Ensembl chr 9:35,332,424...35,418,948
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G |
Cebpa |
CCAAT/enhancer binding protein alpha |
decreases expression multiple interactions |
ISO EXP |
Raloxifene Hydrochloride results in decreased expression of CEBPA mRNA IWR-1 compound inhibits the reaction [Raloxifene Hydrochloride inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CEBPA protein]]; Raloxifene Hydrochloride inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CEBPA protein] |
CTD |
PMID:15849065 PMID:31470850 |
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NCBI chr 7:34,818,718...34,821,353
Ensembl chr 7:34,818,718...34,821,353
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G |
Cebpb |
CCAAT/enhancer binding protein beta |
affects expression multiple interactions increases expression |
ISO |
Raloxifene Hydrochloride affects the expression of CEBPB mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CEBPB mRNA Raloxifene Hydrochloride results in increased expression of CEBPB mRNA |
CTD |
PMID:14699072 PMID:16497877 PMID:19059307 |
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NCBI chr 2:167,530,835...167,532,352
Ensembl chr 2:167,530,835...167,532,338
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G |
Cenpa |
centromere protein A |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of CENPA mRNA |
CTD |
PMID:16514628 |
|
NCBI chr 5:30,824,214...30,832,181
Ensembl chr 5:30,824,121...30,832,174
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G |
Cers6 |
ceramide synthase 6 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CERS6 mRNA |
CTD |
PMID:19059307 |
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NCBI chr 2:68,691,489...68,944,628
Ensembl chr 2:68,691,785...68,944,626
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G |
Cfd |
complement factor D |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CFD mRNA |
CTD |
PMID:15576828 |
|
NCBI chr10:79,726,687...79,728,489
Ensembl chr10:79,726,687...79,728,489
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G |
Chrd |
chordin |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of CHRD mRNA |
CTD |
PMID:14699072 |
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NCBI chr16:20,551,528...20,561,132
Ensembl chr16:20,551,877...20,561,134
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G |
Cish |
cytokine inducible SH2-containing protein |
multiple interactions |
EXP |
Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased expression of CISH mRNA] |
CTD |
PMID:12072388 |
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NCBI chr 9:107,173,858...107,179,983
Ensembl chr 9:107,173,225...107,179,983
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G |
Ckb |
creatine kinase, brain |
increases activity multiple interactions |
ISO |
Raloxifene Hydrochloride results in increased activity of CKB protein Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased activity of CKB protein] |
CTD |
PMID:16621514 PMID:17029789 |
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NCBI chr12:111,635,789...111,638,772
Ensembl chr12:111,635,795...111,638,772
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G |
Clcn4 |
chloride channel, voltage-sensitive 4 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CLCN4 mRNA |
CTD |
PMID:19059307 |
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NCBI chr 7:7,285,308...7,303,837
Ensembl chr 7:7,285,308...7,303,850
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G |
Clcn6 |
chloride channel, voltage-sensitive 6 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CLCN6 mRNA |
CTD |
PMID:16497877 |
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NCBI chr 4:148,088,716...148,123,270
Ensembl chr 4:148,088,716...148,123,278
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G |
Clic4 |
chloride intracellular channel 4 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CLIC4 mRNA |
CTD |
PMID:16497877 |
|
NCBI chr 4:134,941,280...135,000,071
Ensembl chr 4:134,941,280...135,000,125
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G |
Clk1 |
CDC-like kinase 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CLK1 mRNA |
CTD |
PMID:12154049 |
|
NCBI chr 1:58,451,147...58,463,247
Ensembl chr 1:58,449,348...58,463,225
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G |
Clmn |
calmin |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CLMN mRNA |
CTD |
PMID:26865669 |
|
NCBI chr12:104,729,373...104,831,335
Ensembl chr12:104,729,376...104,831,335
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G |
Clstn1 |
calsyntenin 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of CLSTN1 mRNA |
CTD |
PMID:16514628 |
|
NCBI chr 4:149,670,536...149,733,356
Ensembl chr 4:149,670,925...149,733,356
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G |
Cltb |
clathrin light chain B |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of CLTB mRNA |
CTD |
PMID:14699072 |
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NCBI chr13:54,740,199...54,759,186
Ensembl chr13:54,740,214...54,759,157
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G |
Clu |
clusterin |
increases expression |
EXP ISO |
Raloxifene Hydrochloride results in increased expression of CLU mRNA |
CTD |
PMID:12370124 PMID:16202921 |
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NCBI chr14:66,206,093...66,218,992
Ensembl chr14:66,205,932...66,218,996
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G |
Cnbp |
cellular nucleic acid binding protein |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CNBP mRNA |
CTD |
PMID:12154049 |
|
NCBI chr 6:87,819,597...87,828,088
Ensembl chr 6:87,819,597...87,828,088
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G |
Col10a1 |
collagen, type X, alpha 1 |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Decitabine results in increased expression of COL10A1 mRNA] |
CTD |
PMID:23385821 |
|
NCBI chr10:34,265,977...34,273,081
Ensembl chr10:34,265,977...34,273,081
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G |
Col11a1 |
collagen, type XI, alpha 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of COL11A1 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 3:113,823,933...114,014,405
Ensembl chr 3:113,824,189...114,014,367
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G |
Col1a2 |
collagen, type I, alpha 2 |
decreases expression |
EXP |
Raloxifene Hydrochloride results in decreased expression of COL1A2 mRNA |
CTD |
PMID:19401787 |
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NCBI chr 6:4,505,618...4,541,543
Ensembl chr 6:4,504,814...4,541,544
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G |
Col26a1 |
collagen, type XXVI, alpha 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of COL26A1 mRNA |
CTD |
PMID:17962382 |
|
NCBI chr 5:136,770,613...136,912,230
Ensembl chr 5:136,770,613...136,912,063
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G |
Col2a1 |
collagen, type II, alpha 1 |
multiple interactions |
ISO |
Raloxifene Hydrochloride promotes the reaction [Decitabine results in decreased expression of COL2A1 mRNA] |
CTD |
PMID:23385821 |
|
NCBI chr15:97,873,483...97,902,525
Ensembl chr15:97,873,483...97,902,576
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G |
Col5a1 |
collagen, type V, alpha 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of COL5A1 mRNA |
CTD |
PMID:16079270 |
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NCBI chr 2:27,776,393...27,929,522
Ensembl chr 2:27,776,437...27,929,526
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G |
Col5a2 |
collagen, type V, alpha 2 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of COL5A2 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 1:45,413,491...45,542,442
Ensembl chr 1:45,413,481...45,542,442
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G |
Copb2 |
COPI coat complex subunit beta 2 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of COPB2 mRNA |
CTD |
PMID:16514628 |
|
NCBI chr 9:98,445,784...98,470,428
Ensembl chr 9:98,445,774...98,470,435
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G |
Cpb2 |
carboxypeptidase B2 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of CPB2 protein |
CTD |
PMID:16167916 |
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NCBI chr14:75,479,727...75,520,995
Ensembl chr14:75,479,727...75,520,995
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G |
Cpe |
carboxypeptidase E |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of CPE mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 8:65,045,576...65,146,143
Ensembl chr 8:65,045,576...65,146,088
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G |
Cpm |
carboxypeptidase M |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CPM mRNA |
CTD |
PMID:19429434 |
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NCBI chr10:117,465,405...117,523,257
Ensembl chr10:117,465,405...117,523,257
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G |
Creb1 |
cAMP responsive element binding protein 1 |
increases phosphorylation |
ISO |
Raloxifene Hydrochloride results in increased phosphorylation of CREB1 protein |
CTD |
PMID:24782323 |
|
NCBI chr 1:64,571,963...64,643,707
Ensembl chr 1:64,571,804...64,643,707
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G |
Crebbp |
CREB binding protein |
multiple interactions |
ISO |
Raloxifene Hydrochloride promotes the reaction [CREBBP protein binds to IGF1 promoter]; Raloxifene Hydrochloride promotes the reaction [CREBBP protein binds to PTGS2 promoter] |
CTD |
PMID:17872375 |
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NCBI chr16:3,899,198...4,031,864
Ensembl chr16:3,899,192...4,031,861
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G |
Crispld2 |
cysteine-rich secretory protein LCCL domain containing 2 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of CRISPLD2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CRISPLD2 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 8:120,719,177...120,779,533
Ensembl chr 8:120,719,177...120,779,532
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G |
Crybb2 |
crystallin, beta B2 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of CRYBB2 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 5:113,206,124...113,217,983
Ensembl chr 5:113,206,124...113,217,983
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G |
Csdc2 |
cold shock domain containing C2, RNA binding |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CSDC2 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr15:81,820,960...81,835,142
Ensembl chr15:81,820,960...81,835,142
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G |
Csf1 |
colony stimulating factor 1 (macrophage) |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CSF1 mRNA |
CTD |
PMID:12154049 |
|
NCBI chr 3:107,648,364...107,668,048
Ensembl chr 3:107,648,364...107,667,785
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G |
Csf1r |
colony stimulating factor 1 receptor |
multiple interactions |
ISO |
[9,10-Dimethyl-1,2-benzanthracene co-treated with Raloxifene Hydrochloride co-treated with Fluoxetine] affects the expression of CSF1R protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with Raloxifene Hydrochloride] affects the expression of CSF1R protein |
CTD |
PMID:31332895 |
|
NCBI chr18:61,238,644...61,264,211
Ensembl chr18:61,233,670...61,265,221
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G |
Csf2 |
colony stimulating factor 2 (granulocyte-macrophage) |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of CSF2 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr11:54,138,096...54,140,725
Ensembl chr11:54,138,097...54,140,493
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G |
Csf3 |
colony stimulating factor 3 (granulocyte) |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of CSF3 mRNA |
CTD |
PMID:16298037 |
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NCBI chr11:98,591,287...98,594,457
Ensembl chr11:98,592,089...98,594,455
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G |
Ctnnb1 |
catenin beta 1 |
increases expression multiple interactions |
EXP ISO |
Raloxifene Hydrochloride results in increased expression of CTNNB1 protein [Raloxifene Hydrochloride co-treated with Bexarotene] affects the reaction [Azoxymethane affects the expression of CTNNB1 mRNA]; [Raloxifene Hydrochloride co-treated with Bexarotene] affects the reaction [Azoxymethane affects the expression of CTNNB1 protein] [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of CTNNB1 mRNA; IWR-1 compound inhibits the reaction [Raloxifene Hydrochloride inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CTNNB1 protein]]; Raloxifene Hydrochloride inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CTNNB1 protein] |
CTD |
PMID:24080207 PMID:24431404 PMID:25571714 PMID:31470850 |
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NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573
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G |
Ctsb |
cathepsin B |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of CTSB mRNA |
CTD |
PMID:16079270 |
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NCBI chr14:63,359,911...63,383,372
Ensembl chr14:63,359,911...63,383,372
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G |
Ctsh |
cathepsin H |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CTSH mRNA |
CTD |
PMID:16514628 |
|
NCBI chr 9:89,936,320...89,958,148
Ensembl chr 9:89,936,205...89,958,142
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G |
Ctsk |
cathepsin K |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of CTSK mRNA |
CTD |
PMID:17166402 |
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NCBI chr 3:95,406,521...95,416,698
Ensembl chr 3:95,406,567...95,416,673
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G |
Cuedc1 |
CUE domain containing 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CUEDC1 mRNA |
CTD |
PMID:19059307 |
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NCBI chr11:87,989,972...88,084,966
Ensembl chr11:87,988,884...88,084,966
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G |
Cxadr |
coxsackie virus and adenovirus receptor |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of CXADR mRNA |
CTD |
PMID:14699072 |
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NCBI chr16:78,098,114...78,156,673
Ensembl chr16:78,098,377...78,156,662
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G |
Cxcl10 |
C-X-C motif chemokine ligand 10 |
multiple interactions |
EXP |
Raloxifene Hydrochloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of CXCL10 mRNA]; Raloxifene Hydrochloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of CXCL10 protein] |
CTD |
PMID:19533603 |
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NCBI chr 5:92,494,497...92,496,748
Ensembl chr 5:92,494,497...92,496,748
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G |
Cxcl12 |
C-X-C motif chemokine ligand 12 |
multiple interactions decreases expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CXCL12 mRNA; Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of CXCL12 mRNA]; Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased secretion of CXCL12 protein] Raloxifene Hydrochloride results in decreased expression of CXCL12 mRNA |
CTD |
PMID:19059307 PMID:20549624 PMID:21185374 PMID:26865669 |
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NCBI chr 6:117,145,496...117,158,329
Ensembl chr 6:117,145,496...117,158,328
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G |
Cxcl15 |
C-X-C motif chemokine ligand 15 |
multiple interactions |
ISO EXP |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CXCL8 mRNA Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased expression of CXCL5 mRNA] |
CTD |
PMID:12072388 PMID:19059307 |
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NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
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G |
Cxcl2 |
C-X-C motif chemokine ligand 2 |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of CXCL2 mRNA] |
CTD |
PMID:25305410 |
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NCBI chr 5:91,051,758...91,053,797
Ensembl chr 5:91,051,730...91,053,797
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G |
Cylc2 |
cylicin, basic protein of sperm head cytoskeleton 2 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CYLC2 mRNA |
CTD |
PMID:19429434 |
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NCBI chr 4:51,216,653...51,250,625
Ensembl chr 4:51,216,678...51,250,622
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G |
Cyld |
CYLD lysine 63 deubiquitinase |
increases expression multiple interactions |
EXP |
Raloxifene Hydrochloride results in increased expression of CYLD mRNA [SOD1 protein mutant form affects the susceptibility to Raloxifene Hydrochloride] which results in decreased expression of CYLD mRNA |
CTD |
PMID:33269387 |
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NCBI chr 8:89,423,506...89,478,574
Ensembl chr 8:89,423,675...89,478,573
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G |
Cyp19a1 |
cytochrome P450, family 19, subfamily a, polypeptide 1 |
multiple interactions decreases expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CYP19A1 mRNA Raloxifene Hydrochloride results in decreased expression of CYP19A1 mRNA |
CTD |
PMID:10704911 PMID:19059307 |
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NCBI chr 9:54,073,221...54,175,448
Ensembl chr 9:54,073,221...54,175,394
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
multiple interactions increases expression |
ISO EXP |
[Raloxifene Hydrochloride results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA; Raloxifene Hydrochloride inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein] Raloxifene Hydrochloride results in increased expression of CYP1A1 mRNA; Raloxifene Hydrochloride results in increased expression of CYP1A1 protein ARNT protein affects the reaction [Raloxifene Hydrochloride results in increased expression of CYP1A1 protein] |
CTD |
PMID:18493746 PMID:19901195 PMID:24481452 |
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NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
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G |
Cyp24a1 |
cytochrome P450, family 24, subfamily a, polypeptide 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CYP24A1 mRNA |
CTD |
PMID:19059307 |
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NCBI chr 2:170,324,877...170,339,065
Ensembl chr 2:170,324,628...170,339,065
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G |
Cyp26a1 |
cytochrome P450, family 26, subfamily a, polypeptide 1 |
decreases expression |
EXP |
Raloxifene Hydrochloride results in decreased expression of CYP26A1 mRNA |
CTD |
PMID:29990529 |
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NCBI chr19:37,686,186...37,689,984
Ensembl chr19:37,686,246...37,689,984
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G |
Cyp26b1 |
cytochrome P450, family 26, subfamily b, polypeptide 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CYP26B1 mRNA |
CTD |
PMID:19059307 |
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NCBI chr 6:84,548,396...84,570,890
Ensembl chr 6:84,548,396...84,570,890
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G |
Cyp27a1 |
cytochrome P450, family 27, subfamily a, polypeptide 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of CYP27A1 mRNA |
CTD |
PMID:16079270 |
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NCBI chr 1:74,752,311...74,777,056
Ensembl chr 1:74,752,733...74,777,051
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G |
Cyp27b1 |
cytochrome P450, family 27, subfamily b, polypeptide 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CYP27B1 mRNA |
CTD |
PMID:15795327 |
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NCBI chr10:126,884,115...126,891,897
Ensembl chr10:126,884,119...126,888,875
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G |
Cyp2a22 |
cytochrome P450, family 2, subfamily a, polypeptide 22 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of CYP2A1 mRNA |
CTD |
PMID:16079270 |
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NCBI chr 7:26,631,564...26,638,838
Ensembl chr 7:26,631,056...26,638,809
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G |
Cyp2c29 |
cytochrome P450, family 2, subfamily c, polypeptide 29 |
decreases activity |
ISO |
Raloxifene Hydrochloride results in decreased activity of CYP2C8 protein |
CTD |
PMID:15601807 |
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NCBI chr19:39,275,541...39,319,157
Ensembl chr19:39,257,849...39,319,157
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G |
D430019H16Rik |
RIKEN cDNA D430019H16 gene |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of C14ORF132 mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of C14ORF132 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr12:105,420,115...105,459,354
Ensembl chr12:105,420,115...105,459,354
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G |
Dact1 |
dishevelled-binding antagonist of beta-catenin 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of DACT1 mRNA |
CTD |
PMID:19059307 |
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NCBI chr12:71,356,658...71,366,881
Ensembl chr12:71,356,658...71,366,881
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G |
Dag1 |
dystroglycan 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of DAG1 mRNA |
CTD |
PMID:16497877 |
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NCBI chr 9:108,082,060...108,141,176
Ensembl chr 9:108,081,833...108,141,157
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G |
Daxx |
Fas death domain-associated protein |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of DAXX mRNA |
CTD |
PMID:14699072 |
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NCBI chr17:34,128,379...34,134,564
Ensembl chr17:34,128,388...34,134,564
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G |
Dbp |
D site albumin promoter binding protein |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of DBP mRNA |
CTD |
PMID:15576828 |
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NCBI chr 7:45,354,658...45,359,579
Ensembl chr 7:45,354,512...45,359,627
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G |
Dcbld2 |
discoidin, CUB and LCCL domain containing 2 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of DCBLD2 mRNA |
CTD |
PMID:19059307 |
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NCBI chr16:58,228,789...58,304,013
Ensembl chr16:58,228,806...58,290,090
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G |
Ddit4 |
DNA-damage-inducible transcript 4 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of DDIT4 mRNA |
CTD |
PMID:14699072 |
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NCBI chr10:59,785,497...59,787,592
Ensembl chr10:59,785,491...59,787,656
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G |
Ddx21 |
DExD box helicase 21 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of DDX21 mRNA |
CTD |
PMID:16514628 |
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NCBI chr10:62,416,026...62,438,077
Ensembl chr10:62,416,030...62,438,060
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G |
Ddx3y |
DEAD box helicase 3, Y-linked |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of DDX3Y mRNA |
CTD |
PMID:16514628 |
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NCBI chr Y:1,260,715...1,286,630
Ensembl chr Y:1,260,771...1,286,629
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G |
Ddx50 |
DExD box helicase 50 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of DDX50 mRNA |
CTD |
PMID:16079270 |
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NCBI chr10:62,451,571...62,487,260
Ensembl chr10:62,451,674...62,486,997
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G |
Defb1 |
defensin beta 1 |
multiple interactions |
EXP |
[Progesterone co-treated with Raloxifene Hydrochloride] results in increased expression of DEFB1 mRNA |
CTD |
PMID:18367319 |
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NCBI chr 8:22,266,571...22,285,201
Ensembl chr 8:22,266,615...22,285,201
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G |
Depp1 |
DEPP1 autophagy regulator |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of DEPP1 mRNA |
CTD |
PMID:16298037 |
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NCBI chr 6:116,627,645...116,629,808
Ensembl chr 6:116,627,570...116,629,755
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G |
Desi2 |
desumoylating isopeptidase 2 |
increases expression |
EXP |
Raloxifene Hydrochloride results in increased expression of DESI2 mRNA |
CTD |
PMID:33269387 |
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NCBI chr 1:178,014,983...178,080,164
Ensembl chr 1:178,014,983...178,084,867
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G |
Dhcr24 |
24-dehydrocholesterol reductase |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of DHCR24 mRNA |
CTD |
PMID:15585566 |
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NCBI chr 4:106,418,279...106,446,310
Ensembl chr 4:106,418,235...106,446,310
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G |
Dhrs2 |
dehydrogenase/reductase member 2 |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of DHRS2 mRNA] |
CTD |
PMID:21185374 |
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NCBI chr14:55,459,464...55,478,897
Ensembl chr14:55,459,464...55,478,892
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G |
Dhx9 |
DExH-box helicase 9 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of DHX9 mRNA |
CTD |
PMID:16514628 |
|
NCBI chr 1:153,331,506...153,363,464
Ensembl chr 1:153,331,504...153,363,406
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G |
Dicer1 |
dicer 1, ribonuclease type III |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of DICER1 mRNA |
CTD |
PMID:16497877 |
|
NCBI chr12:104,654,001...104,718,331
Ensembl chr12:104,654,001...104,718,211
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G |
Dkk1 |
dickkopf WNT signaling pathway inhibitor 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of DKK1 protein |
CTD |
PMID:22067277 |
|
NCBI chr19:30,523,276...30,526,896
Ensembl chr19:30,523,263...30,527,065
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G |
Dkk2 |
dickkopf WNT signaling pathway inhibitor 2 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of DKK2 mRNA |
CTD |
PMID:19429434 |
|
NCBI chr 3:131,791,027...131,886,065
Ensembl chr 3:131,791,053...131,886,065
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G |
Dmbt1 |
deleted in malignant brain tumors 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of DMBT1 mRNA; Raloxifene Hydrochloride results in increased expression of DMBT1 protein |
CTD |
PMID:15564322 |
|
NCBI chr 7:130,633,787...130,723,357
Ensembl chr 7:130,633,776...130,723,357
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G |
Dnaja1 |
DnaJ heat shock protein family (Hsp40) member A1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of DNAJA1 mRNA |
CTD |
PMID:16514628 |
|
NCBI chr 4:40,722,468...40,734,965
Ensembl chr 4:40,722,150...40,737,149
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G |
Dnajb1 |
DnaJ heat shock protein family (Hsp40) member B1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of DNAJB1 mRNA |
CTD |
PMID:16497877 |
|
NCBI chr 8:84,334,804...84,339,282
Ensembl chr 8:84,334,822...84,339,282
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G |
Dnajb4 |
DnaJ heat shock protein family (Hsp40) member B4 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of DNAJB4 mRNA |
CTD |
PMID:16497877 |
|
NCBI chr 3:151,887,217...151,915,720
Ensembl chr 3:151,884,148...151,915,939
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G |
Dnajb9 |
DnaJ heat shock protein family (Hsp40) member B9 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of DNAJB9 mRNA |
CTD |
PMID:16497877 |
|
NCBI chr12:44,252,680...44,256,851
Ensembl chr12:44,252,342...44,257,109
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G |
Dnmbp |
dynamin binding protein |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of DNMBP mRNA |
CTD |
PMID:14699072 |
|
NCBI chr19:43,835,259...43,930,930
Ensembl chr19:43,835,260...43,928,630
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G |
Dock9 |
dedicator of cytokinesis 9 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of DOCK9 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr14:121,772,026...122,038,465
Ensembl chr14:121,779,458...122,035,249
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G |
Dram1 |
DNA-damage regulated autophagy modulator 1 |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in decreased expression of DRAM1 mRNA] |
CTD |
PMID:21185374 |
|
NCBI chr10:88,158,663...88,200,218
Ensembl chr10:88,158,666...88,214,942
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G |
Drd5 |
dopamine receptor D5 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of DRD5 mRNA |
CTD |
PMID:19429434 |
|
NCBI chr 5:38,476,742...38,479,868
Ensembl chr 5:38,476,710...38,479,861
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G |
Dusp2 |
dual specificity phosphatase 2 |
decreases expression multiple interactions |
ISO |
Raloxifene Hydrochloride results in decreased expression of DUSP2 mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of DUSP2 mRNA |
CTD |
PMID:16497877 PMID:19059307 |
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NCBI chr 2:127,178,079...127,180,297
Ensembl chr 2:127,178,079...127,180,296
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G |
Dusp4 |
dual specificity phosphatase 4 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of DUSP4 mRNA |
CTD |
PMID:16497877 |
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NCBI chr 8:35,274,448...35,289,106
Ensembl chr 8:35,274,451...35,287,048
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G |
Dusp5 |
dual specificity phosphatase 5 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of DUSP5 mRNA |
CTD |
PMID:19059307 |
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NCBI chr19:53,517,576...53,530,240
Ensembl chr19:53,517,540...53,530,862
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G |
Dusp6 |
dual specificity phosphatase 6 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of DUSP6 mRNA |
CTD |
PMID:16079270 |
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NCBI chr10:99,098,676...99,103,351
Ensembl chr10:99,099,093...99,103,351
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G |
Dync1li2 |
dynein, cytoplasmic 1 light intermediate chain 2 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of DYNC1LI2 mRNA |
CTD |
PMID:14699072 |
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NCBI chr 8:105,144,306...105,170,415
Ensembl chr 8:105,144,312...105,169,679
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G |
Dynll1 |
dynein light chain LC8-type 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of DYNLL1 mRNA |
CTD |
PMID:12154049 |
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NCBI chr 5:115,435,129...115,438,995
Ensembl chr 5:115,435,169...115,439,058
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G |
Dyrk2 |
dual-specificity tyrosine phosphorylation regulated kinase 2 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of DYRK2 mRNA |
CTD |
PMID:26865669 |
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NCBI chr10:118,691,507...118,725,144
Ensembl chr10:118,691,508...118,706,114
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G |
E2f1 |
E2F transcription factor 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with PX-866] results in decreased expression of E2F1 mRNA |
CTD |
PMID:26660119 |
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NCBI chr 2:154,401,320...154,411,812
Ensembl chr 2:154,401,327...154,411,812
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G |
E2f2 |
E2F transcription factor 2 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of E2F2 mRNA |
CTD |
PMID:16497877 |
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NCBI chr 4:135,899,585...135,923,368
Ensembl chr 4:135,899,705...135,923,368
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G |
Eci1 |
enoyl-Coenzyme A delta isomerase 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ECI1 mRNA |
CTD |
PMID:16079270 |
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NCBI chr17:24,645,657...24,658,290
Ensembl chr17:24,645,615...24,658,322
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G |
Edn3 |
endothelin 3 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of EDN3 mRNA ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of EDN3 mRNA] |
CTD |
PMID:14699072 |
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NCBI chr 2:174,602,412...174,625,835
Ensembl chr 2:174,602,412...174,625,835
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G |
Ednra |
endothelin receptor type A |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of EDNRA mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of EDNRA mRNA |
CTD |
PMID:19059307 |
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NCBI chr 8:78,389,658...78,451,081
Ensembl chr 8:78,389,660...78,451,093
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G |
Efemp1 |
epidermal growth factor-containing fibulin-like extracellular matrix protein 1 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of EFEMP1 mRNA Raloxifene Hydrochloride inhibits the reaction [Estradiol results in decreased expression of EFEMP1 mRNA] |
CTD |
PMID:14699072 PMID:21185374 |
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NCBI chr11:28,803,154...28,876,743
Ensembl chr11:28,803,204...28,876,743
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G |
Efna1 |
ephrin A1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of EFNA1 mRNA |
CTD |
PMID:26865669 |
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NCBI chr 3:89,179,037...89,188,258
Ensembl chr 3:89,179,040...89,188,449
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G |
Egfr |
epidermal growth factor receptor |
multiple interactions increases phosphorylation decreases phosphorylation |
ISO |
[Raloxifene Hydrochloride co-treated with epigallocatechin gallate] results in decreased phosphorylation of EGFR protein; Raloxifene Hydrochloride results in decreased expression of and affects the localization of EGFR protein Raloxifene Hydrochloride results in increased phosphorylation of EGFR protein Raloxifene Hydrochloride results in decreased phosphorylation of EGFR protein |
CTD |
PMID:18371987 PMID:23842642 PMID:24782323 |
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NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158
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G |
Egln3 |
egl-9 family hypoxia-inducible factor 3 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of EGLN3 mRNA |
CTD |
PMID:16079270 |
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NCBI chr12:54,225,767...54,250,660
Ensembl chr12:54,225,767...54,250,646
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G |
Egr1 |
early growth response 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of EGR1 mRNA |
CTD |
PMID:19059307 |
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NCBI chr18:34,994,260...34,998,009
Ensembl chr18:34,992,876...34,998,037
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G |
Egr3 |
early growth response 3 |
multiple interactions decreases expression |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of EGR3 mRNA] Raloxifene Hydrochloride results in decreased expression of EGR3 mRNA |
CTD |
PMID:21185374 PMID:26865669 |
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NCBI chr14:70,314,766...70,320,062
Ensembl chr14:70,314,652...70,320,063
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G |
Eif1 |
eukaryotic translation initiation factor 1 |
multiple interactions increases expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of EIF1 mRNA Raloxifene Hydrochloride results in increased expression of EIF1 mRNA |
CTD |
PMID:16497877 PMID:19059307 |
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NCBI chr11:100,210,775...100,212,925
Ensembl chr11:100,210,711...100,212,922
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G |
Eif2s1 |
eukaryotic translation initiation factor 2, subunit 1 alpha |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of EIF2S1 mRNA |
CTD |
PMID:16514628 |
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NCBI chr12:78,908,846...78,933,784
Ensembl chr12:78,908,593...78,933,784
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G |
Eif5 |
eukaryotic translation initiation factor 5 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of EIF5 mRNA |
CTD |
PMID:16514628 |
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NCBI chr12:111,504,535...111,513,187
Ensembl chr12:111,504,450...111,513,186
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G |
Eif5a |
eukaryotic translation initiation factor 5A |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of EIF5A mRNA |
CTD |
PMID:16497877 |
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NCBI chr11:69,807,538...69,812,784
Ensembl chr11:69,807,540...69,812,784
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G |
Elf3 |
E74-like factor 3 |
multiple interactions increases expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ELF3 mRNA Raloxifene Hydrochloride results in increased expression of ELF3 mRNA |
CTD |
PMID:16202921 PMID:19059307 |
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NCBI chr 1:135,181,312...135,186,210
Ensembl chr 1:135,181,313...135,186,306
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G |
Ell |
elongation factor RNA polymerase II |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of ELL mRNA |
CTD |
PMID:15849065 |
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NCBI chr 8:70,992,345...71,045,508
Ensembl chr 8:70,992,107...71,045,508
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G |
Elob |
elongin B |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of ELOB mRNA |
CTD |
PMID:16514628 |
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NCBI chr17:24,043,714...24,048,083
Ensembl chr17:24,043,712...24,048,110
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G |
Elovl5 |
ELOVL fatty acid elongase 5 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of ELOVL5 mRNA |
CTD |
PMID:16514628 |
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NCBI chr 9:77,824,647...77,891,801
Ensembl chr 9:77,824,646...77,891,801
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G |
Emp1 |
epithelial membrane protein 1 |
multiple interactions |
ISO |
ESR1 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of EMP1 mRNA] |
CTD |
PMID:14699072 |
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NCBI chr 6:135,339,548...135,360,171
Ensembl chr 6:135,339,543...135,360,171
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G |
Enc1 |
ectodermal-neural cortex 1 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of ENC1 mRNA [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of ENC1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ENC1 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr13:97,377,613...97,389,548
Ensembl chr13:97,377,613...97,389,542
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G |
Endod1 |
endonuclease domain containing 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ENDOD1 mRNA |
CTD |
PMID:19059307 |
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NCBI chr 9:14,265,286...14,292,538
Ensembl chr 9:14,265,286...14,292,803
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G |
Eng |
endoglin |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of ENG mRNA; Raloxifene Hydrochloride results in increased expression of ENG protein |
CTD |
PMID:20135064 PMID:32947957 |
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NCBI chr 2:32,536,607...32,572,681
Ensembl chr 2:32,536,607...32,572,681
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G |
Eno2 |
enolase 2, gamma neuronal |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ENO2 mRNA |
CTD |
PMID:14699072 |
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NCBI chr 6:124,737,018...124,746,489
Ensembl chr 6:124,737,016...124,746,636
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G |
Enpp2 |
ectonucleotide pyrophosphatase/phosphodiesterase 2 |
multiple interactions affects expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of ENPP2 mRNA Raloxifene Hydrochloride affects the expression of ENPP2 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr15:54,702,297...54,816,284
Ensembl chr15:54,702,297...54,816,288
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G |
Entpd2 |
ectonucleoside triphosphate diphosphohydrolase 2 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of ENTPD2 mRNA |
CTD |
PMID:15576828 |
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NCBI chr 2:25,285,886...25,291,335
Ensembl chr 2:25,285,886...25,291,333
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G |
Epcam |
epithelial cell adhesion molecule |
multiple interactions |
EXP |
[APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of EPCAM mRNA; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of EPCAM protein |
CTD |
PMID:24431404 |
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NCBI chr17:87,943,407...87,958,555
Ensembl chr17:87,943,407...87,958,557
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G |
Epha1 |
Eph receptor A1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of EPHA1 mRNA |
CTD |
PMID:12154049 |
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NCBI chr 6:42,335,421...42,350,249
Ensembl chr 6:42,335,421...42,350,202
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G |
Epha4 |
Eph receptor A4 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of EPHA4 mRNA |
CTD |
PMID:26865669 |
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NCBI chr 1:77,343,819...77,491,763
Ensembl chr 1:77,343,822...77,491,725
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G |
Epor |
erythropoietin receptor |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of EPOR mRNA |
CTD |
PMID:14699072 |
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NCBI chr 9:21,870,193...21,874,915
Ensembl chr 9:21,870,193...21,874,802
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G |
Erbb2 |
erb-b2 receptor tyrosine kinase 2 |
decreases response to substance |
EXP |
ERBB2 protein results in decreased susceptibility to Raloxifene Hydrochloride |
CTD |
PMID:16609042 |
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NCBI chr11:98,303,310...98,328,542
Ensembl chr11:98,303,296...98,328,542
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G |
Erbb3 |
erb-b2 receptor tyrosine kinase 3 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ERBB3 mRNA |
CTD |
PMID:14699072 |
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NCBI chr10:128,403,392...128,425,504
Ensembl chr10:128,403,392...128,425,521
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G |
Erbb4 |
erb-b2 receptor tyrosine kinase 4 |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in decreased expression of ERBB4 mRNA] |
CTD |
PMID:21185374 |
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NCBI chr 1:68,071,063...69,147,756
Ensembl chr 1:68,071,345...69,147,218
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G |
Esr1 |
estrogen receptor 1 (alpha) |
affects response to substance increases response to substance multiple interactions affects folding affects binding decreases activity decreases expression increases expression affects expression |
ISO EXP |
ESR1 gene polymorphism affects the susceptibility to Raloxifene Hydrochloride ESR1 exon polymorphism results in increased susceptibility to Raloxifene Hydrochloride [ESR1 protein co-treated with ESR2 protein] affects the reaction [Raloxifene Hydrochloride results in increased cleavage of PARP1 protein]; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of ANKRD28 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of CCN3 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of CSF2 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of ENC1 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of HAS2 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of KCNN4 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of LINC00312 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of LMCD1 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of PLAU mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of RGS16 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of SLN mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of TGFBI mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of TNFRSF11B mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of TXNIP mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of CA12 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of CRISPLD2 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of EDNRA mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of EIF1 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of ENPP2 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of FHL2 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of G0S2 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of GRK5 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of HEG1 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of HK1 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of IDH2 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of ISG20 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of KCTD12 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of KLRC2 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of LPL mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of MSMB mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of NLRP3 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of NPR2 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of OSBPL3 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of PFKFB3 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of PTPRE mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of RASGRP1 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of RET mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of RGS4 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of RHOBTB3 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of RIPOR2 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of SEMA3B mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of SGK1 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of SYBU mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of TIPARP mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of TMOD1 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of TMPRSS3 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of ZNF395 mRNA; ARID5A protein inhibits the reaction [Raloxifene Hydrochloride results in increased activity of ESR1 protein]; ESR1 protein affects the reaction [Raloxifene Hydrochloride affects the localization of FOXO3 protein]; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of EMP1 mRNA]; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of HSPA1B mRNA]; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of MFAP5 mRNA]; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in decreased secretion of IL6 protein]; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of IDH2 mRNA]; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of KLRC2 mRNA]; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of KLRC3 mRNA]; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of PLPP3 mRNA]; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of TGFB3 mRNA]; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of ZFP36 mRNA]; ESR1 protein promotes the reaction [Raloxifene Hydrochloride results in increased activity of TERT protein]; Raloxifene Hydrochloride affects the folding of and affects the activity of ESR1 protein; Raloxifene Hydrochloride binds to and affects the activity of ESR1 protein; Raloxifene Hydrochloride binds to and results in decreased activity of ESR1 protein; Raloxifene Hydrochloride inhibits the reaction [ESR1 protein binds to CCL3 promoter]; Raloxifene Hydrochloride inhibits the reaction [ESR1 protein binds to RELA protein]; Raloxifene Hydrochloride inhibits the reaction [Estradiol binds to ESR1 protein]; Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of ESR1 protein]; Raloxifene Hydrochloride inhibits the reaction [trichostatin A results in decreased expression of ESR1 mRNA]; Raloxifene Hydrochloride promotes the reaction [ESR1 protein binds to IGF1 promoter]; Raloxifene Hydrochloride promotes the reaction [ESR1 protein binds to KLRC3 gene]; Raloxifene Hydrochloride promotes the reaction [ESR1 protein binds to PTGS2 promoter]; Raloxifene Hydrochloride results in increased activity of and affects the localization of ESR1 protein Raloxifene Hydrochloride affects the folding of ESR1 protein [Raloxifene Hydrochloride binds to ESR1 protein] which binds to SERPINB9 protein; [Raloxifene Hydrochloride binds to ESR1 protein] which binds to TFF1 protein; Raloxifene Hydrochloride binds to ESR1 protein Raloxifene Hydrochloride results in decreased activity of ESR1 protein Raloxifene Hydrochloride results in decreased expression of ESR1 mRNA; Raloxifene Hydrochloride results in decreased expression of ESR1 protein Raloxifene Hydrochloride results in increased expression of ESR1 mRNA; Raloxifene Hydrochloride results in increased expression of ESR1 protein ESR1 protein promotes the reaction [Raloxifene Hydrochloride results in increased expression of SLC1A2 mRNA]; ESR1 protein promotes the reaction [Raloxifene Hydrochloride results in increased expression of SLC1A3 mRNA] Raloxifene Hydrochloride metabolite binds to ESR1 protein Raloxifene Hydrochloride affects the expression of ESR1 mRNA [Raloxifene Hydrochloride co-treated with Estradiol] results in decreased expression of ESR1 protein; [Raloxifene Hydrochloride co-treated with Oxygen deficiency] results in increased expression of ESR1 protein; Raloxifene Hydrochloride affects the reaction [Oxygen deficiency affects the expression of ESR1 protein alternative form]; Raloxifene Hydrochloride binds to and affects the folding of ESR1 protein mutant form; Raloxifene Hydrochloride inhibits the reaction [Oxygen deficiency results in decreased expression of ESR1 mRNA] |
CTD |
PMID:9751507 PMID:11535548 PMID:11867264 PMID:14617632 PMID:14699072 PMID:15161930 PMID:15521089 PMID:15807179 PMID:15842231 PMID:15941852 PMID:15961563 PMID:16497877 PMID:16604479 PMID:16790557 PMID:16798746 PMID:17203231 PMID:17299137 PMID:17350824 PMID:17395694 PMID:17654759 PMID:17872375 PMID:18976723 PMID:19059307 PMID:19350480 PMID:19432593 PMID:20362049 PMID:20435135 PMID:21256200 PMID:21543282 PMID:22476901 PMID:22965848 PMID:24782323 PMID:24846829 PMID:25012808 PMID:25571714 PMID:26470790 PMID:26865669 PMID:26879975 PMID:27163517 PMID:27576059 PMID:27721470 PMID:28859903 More...
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NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614
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G |
Esr2 |
estrogen receptor 2 (beta) |
multiple interactions increases response to substance decreases activity increases activity affects expression increases expression |
ISO EXP |
[ESR1 protein co-treated with ESR2 protein] affects the reaction [Raloxifene Hydrochloride results in increased cleavage of PARP1 protein]; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ABCC1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ACKR3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ACSL1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of AGO2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of AKAP1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ARL4C mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ASB13 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of C14ORF132 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of C2CD2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CA12 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CALM1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CASKIN2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CASP7 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CCND1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CDK5R1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CEBPB mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CERS6 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CLCN4 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CRISPLD2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CSDC2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CUEDC1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CYP19A1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CYP24A1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CYP26B1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of DOCK9 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of EDNRA mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ELF3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ENDOD1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of EVI2A mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FADD mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FGD6 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FGFR2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FHL2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FLNB mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FOSL2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FOXO1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FST mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of GPRC5C mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HEG1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HK1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HMOX1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HPCAL1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HSPB8 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HTR3A mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of INPP5A mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of IVL mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of KAZN mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of KCTD12 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of KIF3C mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of KLRC3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of KLRK1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of LBH mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of LMNB2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of LRIG1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of LRRC20 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of LYSMD4 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MAFF mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MAGEA8 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MAP3K5 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MAP3K8 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MAPKAPK2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MBNL2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MDFIC mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MEF2A mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MMP12 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MN1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MPPED2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MYT1L mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NAV2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NCF2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NCOA1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NCOA4 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NDRG4 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NFATC1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NFIL3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NFKBIA mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NINJ1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NPR2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NR1D1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NR2F6 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NUAK1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of OSBPL3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of OTUB2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PCTP mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PDLIM3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PHC2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PHF11 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PITPNC1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PRKCZ mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PTGER3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PTGES mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of RCOR3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of RET mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of RETREG1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of RFTN1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of RGL1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of RHOF mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of RPS6KA2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SALL1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SCNN1A mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SEMA3F mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SERPINB6 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SLC18A3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SREBF1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SSH1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ST3GAL1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of STK24 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SYBU mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SYNJ2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SYNPO mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of TACC1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of TACC2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of TBXA2R mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of TGFA mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of TMOD1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of TNS3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of TOB1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of TRAF3IP2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of UPF1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of WNT5A mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ZCCHC24 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ZMIZ1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ZNF395 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ADAM19 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ADORA2B mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of AMIGO2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ANKRD1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of AREG mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ATF3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of BIRC3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CCL2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CCL20 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CDH2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CDO1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CXCL12 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CXCL8 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of DACT1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of DCBLD2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of DUSP2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of DUSP5 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of EGR1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ENC1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of FUT9 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of GAD1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of GRB10 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of GYG1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of HBEGF mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ID4 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of IFNGR2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of INHBA mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of JAG1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of KRT17 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of KRT34 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of LDLRAD4 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of LMCD1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of MAP2K3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of NAB1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of NFKBIE mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of NR3C1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of NR4A3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of OCLN mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of PCDH7 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of PDP1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of PTGS2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of PTP4A3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of PTX3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of RASGRP1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of RCAN2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of RFK mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of RGS4 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of RRAD mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of SERPINE1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of SLCO4C1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of SOD2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TCIM mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TGFB2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TGFBI mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TMEM158 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TNC mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TNFRSF11B mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TNFRSF21 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TNIK mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TRAF5 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TRIB1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TRIM36 mRNA; [trichostatin A co-treated with Estradiol co-treated with Raloxifene Hydrochloride] results in increased expression of ESR2 protein; [trichostatin A co-treated with Raloxifene Hydrochloride] results in increased expression of ESR2 mRNA; [trichostatin A co-treated with Raloxifene Hydrochloride] results in increased expression of ESR2 protein; ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of EDN3 mRNA]; ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of FLNB mRNA]; ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of IER3 mRNA]; ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of KLRC2 mRNA]; ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of MSMB mRNA]; ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of NCF2 mRNA]; ESR2 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of GABRR1 mRNA]; ESR2 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of TMT1A mRNA]; ESR2 protein promotes the reaction [Raloxifene Hydrochloride results in increased activity of TERT protein]; Raloxifene Hydrochloride binds to and results in increased activity of ESR2 protein; Raloxifene Hydrochloride inhibits the reaction [3,3'-diindolylmethane results in increased expression of ESR2 mRNA]; Raloxifene Hydrochloride promotes the reaction [[trichostatin A co-treated with Estradiol] results in increased expression of ESR2 mRNA]; Raloxifene Hydrochloride promotes the reaction [ESR2 protein binds to ESR2 protein]; Raloxifene Hydrochloride promotes the reaction [ESR2 protein binds to IGF1 promoter]; Raloxifene Hydrochloride promotes the reaction [ESR2 protein binds to PTGS2 promoter] ESR2 protein results in increased susceptibility to Raloxifene Hydrochloride Raloxifene Hydrochloride results in decreased activity of ESR2 protein Raloxifene Hydrochloride results in increased activity of ESR2 protein [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of ESR2 protein; ESR2 protein affects the reaction [Raloxifene Hydrochloride inhibits the reaction [Streptozocin results in decreased secretion of MMP2 protein]]; Raloxifene Hydrochloride binds to and affects the activity of ESR2 protein alternative form; Raloxifene Hydrochloride inhibits the reaction [Oxygen deficiency results in increased expression of ESR2 mRNA]; Raloxifene Hydrochloride inhibits the reaction [Oxygen deficiency results in increased expression of ESR2 protein] [Raloxifene Hydrochloride co-treated with Bexarotene] affects the reaction [Azoxymethane affects the expression of ESR2 mRNA]; [Raloxifene Hydrochloride co-treated with Bexarotene] affects the reaction [Azoxymethane affects the expression of ESR2 protein]; ESR2 protein promotes the reaction [Raloxifene Hydrochloride results in increased expression of SLC1A2 mRNA]; ESR2 protein promotes the reaction [Raloxifene Hydrochloride results in increased expression of SLC1A3 mRNA]; Raloxifene Hydrochloride affects the reaction [Azoxymethane affects the expression of ESR2 mRNA]; Raloxifene Hydrochloride affects the reaction [Azoxymethane affects the expression of ESR2 protein] Raloxifene Hydrochloride affects the expression of ESR2 mRNA Raloxifene Hydrochloride results in increased expression of ESR2 protein |
CTD |
PMID:14699072 PMID:15924412 PMID:16798746 PMID:17638070 PMID:17654759 PMID:17872375 PMID:17962382 PMID:19059307 PMID:19350480 PMID:20160136 PMID:22398780 PMID:22476901 PMID:22965848 PMID:23471663 PMID:24080207 PMID:24431404 PMID:24782323 PMID:24846829 PMID:36513145 More...
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NCBI chr12:76,167,193...76,224,033
Ensembl chr12:76,167,193...76,224,033
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G |
Evi2a |
ecotropic viral integration site 2a |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of EVI2A mRNA |
CTD |
PMID:19059307 |
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NCBI chr11:79,417,386...79,421,435
Ensembl chr11:79,417,386...79,421,435
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G |
F11 |
coagulation factor XI |
increases activity |
ISO |
Raloxifene Hydrochloride results in increased activity of F11 protein |
CTD |
PMID:16359964 |
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NCBI chr 8:45,693,696...45,715,092
Ensembl chr 8:45,694,211...45,715,068
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G |
F12 |
coagulation factor XII (Hageman factor) |
increases activity |
ISO |
Raloxifene Hydrochloride results in increased activity of F12 protein |
CTD |
PMID:16359964 |
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NCBI chr13:55,565,771...55,574,617
Ensembl chr13:55,565,771...55,574,606
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G |
F13a1 |
coagulation factor XIII, A1 subunit |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of F13A1 mRNA |
CTD |
PMID:14699072 |
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NCBI chr13:37,051,150...37,234,220
Ensembl chr13:37,051,152...37,234,220
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G |
F2r |
coagulation factor II thrombin receptor |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of F2R mRNA |
CTD |
PMID:12154049 |
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NCBI chr13:95,738,288...95,754,974
Ensembl chr13:95,738,311...95,754,995
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G |
F8 |
coagulation factor VIII |
increases activity increases expression |
ISO |
Raloxifene Hydrochloride results in increased activity of F8 protein Raloxifene Hydrochloride results in increased expression of F8 protein |
CTD |
PMID:15850603 PMID:16359964 |
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NCBI chr X:74,213,950...74,426,342
Ensembl chr X:74,216,321...74,426,221
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G |
Fabp4 |
fatty acid binding protein 4, adipocyte |
increases expression multiple interactions |
EXP |
Raloxifene Hydrochloride results in increased expression of FABP4 mRNA Raloxifene Hydrochloride affects the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of FABP4 protein] |
CTD |
PMID:16643890 PMID:31470850 |
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NCBI chr 3:10,269,406...10,273,653
Ensembl chr 3:10,269,148...10,273,636
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G |
Fadd |
Fas associated via death domain |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FADD mRNA |
CTD |
PMID:19059307 |
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NCBI chr 7:144,132,060...144,136,178
Ensembl chr 7:144,131,055...144,136,200
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G |
Fam171b |
family with sequence similarity 171, member B |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with Estradiol] results in increased expression of FAM171B mRNA |
CTD |
PMID:21185374 |
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NCBI chr 2:83,642,889...83,713,878
Ensembl chr 2:83,642,980...83,713,830
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G |
Fap |
fibroblast activation protein |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of FAP mRNA |
CTD |
PMID:14699072 |
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NCBI chr 2:62,331,280...62,404,365
Ensembl chr 2:62,331,287...62,404,419
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G |
Fgd6 |
FYVE, RhoGEF and PH domain containing 6 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FGD6 mRNA |
CTD |
PMID:19059307 |
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NCBI chr10:93,871,862...93,981,201
Ensembl chr10:93,871,863...93,981,201
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G |
Fgf8 |
fibroblast growth factor 8 |
increases expression |
EXP |
Raloxifene Hydrochloride results in increased expression of FGF8 mRNA |
CTD |
PMID:29990529 |
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NCBI chr19:45,724,930...45,731,380
Ensembl chr19:45,725,237...45,731,354
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G |
Fgf9 |
fibroblast growth factor 9 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of FGF9 mRNA |
CTD |
PMID:16079270 |
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NCBI chr14:58,308,543...58,350,311
Ensembl chr14:58,308,004...58,350,177
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G |
Fgfr2 |
fibroblast growth factor receptor 2 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FGFR2 mRNA |
CTD |
PMID:19059307 |
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NCBI chr 7:129,764,181...129,868,538
Ensembl chr 7:129,764,181...132,725,079
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G |
Fhl1 |
four and a half LIM domains 1 |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of FHL1 mRNA] |
CTD |
PMID:21185374 |
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NCBI chr X:55,776,569...55,838,704
Ensembl chr X:55,777,147...55,838,706
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G |
Fhl2 |
four and a half LIM domains 2 |
multiple interactions affects expression decreases expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of FHL2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FHL2 mRNA Raloxifene Hydrochloride affects the expression of FHL2 mRNA Raloxifene Hydrochloride results in decreased expression of FHL2 mRNA |
CTD |
PMID:14699072 PMID:19059307 PMID:26865669 |
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NCBI chr 1:43,162,233...43,237,501
Ensembl chr 1:43,162,234...43,236,144
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G |
Fis1 |
fission, mitochondrial 1 |
affects expression increases expression |
ISO |
Raloxifene Hydrochloride affects the expression of FIS1 mRNA Raloxifene Hydrochloride results in increased expression of FIS1 mRNA |
CTD |
PMID:15576828 PMID:16079270 |
|
NCBI chr 5:136,982,129...136,995,088
Ensembl chr 5:136,982,129...136,995,088
|
|
G |
Fkbp3 |
FK506 binding protein 3 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of FKBP3 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr12:65,109,206...65,120,712
Ensembl chr12:65,109,198...65,120,781
|
|
G |
Fkbp5 |
FK506 binding protein 5 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of FKBP5 mRNA |
CTD |
PMID:22217510 |
|
NCBI chr17:28,617,727...28,705,123
Ensembl chr17:28,618,068...28,736,501
|
|
G |
Flnb |
filamin, beta |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of FLNB mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FLNB mRNA; ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of FLNB mRNA] |
CTD |
PMID:14699072 PMID:19059307 |
|
NCBI chr14:14,518,185...14,651,852
Ensembl chr14:14,518,185...14,651,816
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|
G |
Flnc |
filamin C, gamma |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of FLNC mRNA |
CTD |
PMID:16514628 |
|
NCBI chr 6:29,433,150...29,461,888
Ensembl chr 6:29,433,255...29,461,882
|
|
G |
Flrt1 |
fibronectin leucine rich transmembrane protein 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of FLRT1 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr19:7,064,829...7,143,548
Ensembl chr19:7,069,366...7,083,094
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|
G |
Fmnl1 |
formin-like 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of FMNL1 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr11:103,061,401...103,089,727
Ensembl chr11:103,061,933...103,089,727
|
|
G |
Fn1 |
fibronectin 1 |
multiple interactions |
EXP |
Raloxifene Hydrochloride inhibits the reaction [TGFB1 protein results in increased expression of FN1 mRNA] |
CTD |
PMID:15920148 |
|
NCBI chr 1:71,624,632...71,692,439
Ensembl chr 1:71,624,679...71,692,359
|
|
G |
Fosl2 |
fos-like antigen 2 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FOSL2 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 5:32,292,599...32,315,184
Ensembl chr 5:32,293,145...32,315,186
|
|
G |
Foxa2 |
forkhead box A2 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of FOXA2 mRNA |
CTD |
PMID:23184660 |
|
NCBI chr 2:147,884,797...147,888,889
Ensembl chr 2:147,884,797...147,888,889
|
|
G |
Foxc1 |
forkhead box C1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of FOXC1 mRNA |
CTD |
PMID:26865669 |
|
NCBI chr13:31,990,629...31,994,618
Ensembl chr13:31,990,616...31,996,459
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G |
Foxe1 |
forkhead box E1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of FOXE1 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 4:46,343,644...46,345,774
Ensembl chr 4:46,343,609...46,346,412
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|
G |
Foxo1 |
forkhead box O1 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of FOXO1 mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FOXO1 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
|
NCBI chr 3:52,175,758...52,257,530
Ensembl chr 3:52,175,757...52,260,642
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|
G |
Foxo3 |
forkhead box O3 |
multiple interactions affects localization |
ISO |
ESR1 protein affects the reaction [Raloxifene Hydrochloride affects the localization of FOXO3 protein]; GPER1 protein affects the reaction [Raloxifene Hydrochloride affects the localization of FOXO3 protein] |
CTD |
PMID:26470790 |
|
NCBI chr10:42,057,841...42,152,691
Ensembl chr10:42,057,837...42,152,751
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|
G |
Fst |
follistatin |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of FST mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FST mRNA |
CTD |
PMID:14699072 PMID:19059307 |
|
NCBI chr13:114,588,798...114,595,522
Ensembl chr13:114,588,826...114,595,487
|
|
G |
Fut9 |
fucosyltransferase 9 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of FUT9 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 4:25,609,333...25,800,003
Ensembl chr 4:25,609,332...25,800,244
|
|
G |
Fyttd1 |
forty-two-three domain containing 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of FYTTD1 mRNA |
CTD |
PMID:16514628 |
|
NCBI chr16:32,697,762...32,729,333
Ensembl chr16:32,697,870...32,729,245
|
|
G |
Fzd6 |
frizzled class receptor 6 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of FZD6 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr15:38,869,673...38,901,587
Ensembl chr15:38,869,429...38,901,583
|
|
G |
G0s2 |
G0/G1 switch gene 2 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of G0S2 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 1:192,954,468...192,955,496
Ensembl chr 1:192,954,469...192,955,525
|
|
G |
Gabarap |
gamma-aminobutyric acid receptor associated protein |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of GABARAP mRNA |
CTD |
PMID:16079270 |
|
NCBI chr11:69,882,196...69,885,775
Ensembl chr11:69,881,969...69,885,777
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|
G |
Gabbr2 |
gamma-aminobutyric acid type B receptor subunit 2 |
multiple interactions |
ISO |
Raloxifene Hydrochloride promotes the reaction [Estradiol results in increased expression of GABBR2 mRNA] |
CTD |
PMID:21185374 |
|
NCBI chr 4:46,662,318...46,991,714
Ensembl chr 4:46,662,305...46,991,873
|
|
G |
Gabpa |
GA repeat binding protein, alpha |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of GABPA mRNA |
CTD |
PMID:12154049 |
|
NCBI chr16:84,631,795...84,660,671
Ensembl chr16:84,631,813...84,660,667
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|
G |
Gabrg1 |
gamma-aminobutyric acid type A receptor subunit gamma 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of GABRG1 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 5:70,906,512...70,999,960
Ensembl chr 5:70,908,390...70,999,960
|
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G |
Gabrr1 |
gamma-aminobutyric acid type A receptor subunit rho 1 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of GABRR1 mRNA ESR2 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of GABRR1 mRNA] |
CTD |
PMID:14699072 |
|
NCBI chr 4:33,132,556...33,163,606
Ensembl chr 4:33,132,521...33,163,588
|
|
G |
Gad1 |
glutamate decarboxylase 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of GAD1 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 2:70,392,109...70,432,358
Ensembl chr 2:70,383,416...70,432,358
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|
G |
Gal |
galanin and GMAP prepropeptide |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of GAL mRNA |
CTD |
PMID:16202921 |
|
NCBI chr19:3,459,915...3,464,544
Ensembl chr19:3,459,915...3,464,544
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G |
Gas6 |
growth arrest specific 6 |
increases expression multiple interactions affects expression |
ISO |
Raloxifene Hydrochloride results in increased expression of GAS6 mRNA fulvestrant inhibits the reaction [Raloxifene Hydrochloride results in increased expression of GAS6 mRNA] Raloxifene Hydrochloride affects the expression of GAS6 mRNA |
CTD |
PMID:16079270 PMID:19429434 |
|
NCBI chr 8:13,515,374...13,544,535
Ensembl chr 8:13,515,374...13,544,490
|
|
G |
Gata2 |
GATA binding protein 2 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of GATA2 mRNA |
CTD |
PMID:19429434 |
|
NCBI chr 6:88,170,873...88,184,014
Ensembl chr 6:88,170,873...88,184,014
|
|
G |
Gcnt1 |
glucosaminyl (N-acetyl) transferase 1, core 2 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of GCNT1 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr19:17,303,505...17,350,208
Ensembl chr19:17,303,505...17,350,208
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G |
Gdf9 |
growth differentiation factor 9 |
increases expression |
EXP |
Raloxifene Hydrochloride results in increased expression of GDF9 mRNA |
CTD |
PMID:22841776 |
|
NCBI chr11:53,321,773...53,328,731
Ensembl chr11:53,321,850...53,328,731
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|
G |
Gfra2 |
glial cell line derived neurotrophic factor family receptor alpha 2 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of GFRA2 mRNA |
CTD |
PMID:15576828 |
|
NCBI chr14:71,127,547...71,217,280
Ensembl chr14:71,127,560...71,217,278
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G |
Gh |
growth hormone |
multiple interactions |
ISO |
Raloxifene Hydrochloride promotes the reaction [GH1 protein results in increased phosphorylation of JAK2 protein] |
CTD |
PMID:17272397 |
|
NCBI chr11:106,191,087...106,194,529
Ensembl chr11:106,191,097...106,192,691
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|
G |
Ghr |
growth hormone receptor |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of GHR mRNA |
CTD |
PMID:16202921 |
|
NCBI chr15:3,347,237...3,612,834
Ensembl chr15:3,347,242...3,612,974
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|
G |
Ghrh |
growth hormone releasing hormone |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of GHRH mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 2:157,171,416...157,190,645
Ensembl chr 2:157,171,417...157,189,426
|
|
G |
Ghrhr |
growth hormone releasing hormone receptor |
affects expression affects response to substance |
ISO |
Raloxifene Hydrochloride affects the expression of GHRHR mRNA GHRHR affects the susceptibility to Raloxifene Hydrochloride |
CTD |
PMID:16079270 PMID:32934756 |
|
NCBI chr 6:55,353,204...55,365,515
Ensembl chr 6:55,353,280...55,365,515
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|
G |
Gjb2 |
gap junction protein, beta 2 |
increases expression |
EXP |
Raloxifene Hydrochloride results in increased expression of GJB2 mRNA |
CTD |
PMID:12370124 |
|
NCBI chr14:57,336,059...57,342,159
Ensembl chr14:57,336,057...57,342,159
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|
G |
Glrb |
glycine receptor, beta subunit |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of GLRB mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 3:80,750,905...80,820,994
Ensembl chr 3:80,750,906...80,820,967
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|
G |
Glrx |
glutaredoxin |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of GLRX mRNA |
CTD |
PMID:14699072 |
|
NCBI chr13:75,988,004...75,998,270
Ensembl chr13:75,987,987...75,998,273
|
|
G |
Glul |
glutamate-ammonia ligase |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of GLUL mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 1:153,775,692...153,785,469
Ensembl chr 1:153,775,690...153,785,469
|
|
G |
Glyat |
glycine-N-acyltransferase |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of GLYAT mRNA |
CTD |
PMID:14699072 |
|
NCBI chr19:12,610,672...12,629,101
Ensembl chr19:12,610,672...12,631,275
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|
G |
Gml2 |
glycosylphosphatidylinositol anchored molecule like 2 |
increases expression |
EXP |
Raloxifene Hydrochloride results in increased expression of GML2 mRNA |
CTD |
PMID:22841776 |
|
NCBI chr15:74,690,791...74,717,997
Ensembl chr15:74,690,920...74,706,720
|
|
G |
Gnb1 |
guanine nucleotide binding protein (G protein), beta 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of GNB1 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 4:155,575,514...155,643,726
Ensembl chr 4:155,575,818...155,643,726
|
|
G |
Gnb4 |
guanine nucleotide binding protein (G protein), beta 4 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of GNB4 mRNA |
CTD |
PMID:19429434 |
|
NCBI chr 3:32,632,736...32,670,813
Ensembl chr 3:32,634,481...32,670,734
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G |
Gnrh1 |
gonadotropin releasing hormone 1 |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol promotes the reaction [GNRH1 protein results in increased secretion of PRL protein]] |
CTD |
PMID:17054466 |
|
NCBI chr14:67,982,717...67,986,889
Ensembl chr14:67,982,630...67,986,888
|
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G |
Golga5 |
golgin A5 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of GOLGA5 mRNA |
CTD |
PMID:16514628 |
|
NCBI chr12:102,435,372...102,464,274
Ensembl chr12:102,435,394...102,464,166
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|
G |
Gpc1 |
glypican 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of GPC1 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 1:92,759,367...92,787,933
Ensembl chr 1:92,759,367...92,788,501
|
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G |
Gpc3 |
glypican 3 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of GPC3 mRNA |
CTD |
PMID:15576828 |
|
NCBI chr X:51,361,303...51,702,851
Ensembl chr X:51,361,303...51,702,827
|
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G |
Gper1 |
G protein-coupled estrogen receptor 1 |
multiple interactions increases activity |
ISO EXP |
[4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline binds to and results in decreased activity of GPER1 protein] inhibits the reaction [[Raloxifene Hydrochloride results in increased activity of GPER1 protein] which results in increased expression of SLC1A2 protein]; [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline results in decreased activity of GPER1 protein] inhibits the reaction [[Raloxifene Hydrochloride results in increased activity of GPER1 protein] which results in increased expression of SLC1A3 protein]; [Raloxifene Hydrochloride results in increased activity of GPER1 protein] which results in increased expression of SLC1A2 protein; [Raloxifene Hydrochloride results in increased activity of GPER1 protein] which results in increased expression of SLC1A3 protein GPER1 protein affects the reaction [Raloxifene Hydrochloride affects the localization of FOXO3 protein]; GPER1 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of AVP mRNA]; GPER1 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of MYC mRNA] Raloxifene Hydrochloride inhibits the reaction [Oxygen deficiency results in increased expression of GPER1 mRNA] |
CTD |
PMID:22453024 PMID:24782323 PMID:24846829 PMID:26200092 PMID:26470790 |
|
NCBI chr 5:139,408,905...139,413,555
Ensembl chr 5:139,408,906...139,413,555
|
|
G |
Gpnmb |
glycoprotein (transmembrane) nmb |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in decreased expression of GPNMB mRNA] |
CTD |
PMID:21185374 |
|
NCBI chr 6:49,013,449...49,044,413
Ensembl chr 6:49,013,480...49,047,863
|
|
G |
Gprc5c |
G protein-coupled receptor, family C, group 5, member C |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of GPRC5C mRNA |
CTD |
PMID:19059307 |
|
NCBI chr11:114,741,976...114,763,443
Ensembl chr11:114,741,978...114,763,443
|
|
G |
Grb10 |
growth factor receptor bound protein 10 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of GRB10 mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of GRB10 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
|
NCBI chr11:11,880,499...11,987,428
Ensembl chr11:11,880,508...11,988,683
|
|
G |
Greb1 |
gene regulated by estrogen in breast cancer protein |
multiple interactions decreases expression |
ISO EXP |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of GREB1 mRNA] Raloxifene Hydrochloride results in decreased expression of GREB1 mRNA |
CTD |
PMID:21185374 PMID:26879975 |
|
NCBI chr12:16,720,616...16,851,395
Ensembl chr12:16,720,616...16,850,887
|
|
G |
Grhl1 |
grainyhead like transcription factor 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of GRHL1 mRNA |
CTD |
PMID:19429434 |
|
NCBI chr12:24,622,234...24,667,390
Ensembl chr12:24,622,282...24,667,390
|
|
G |
Grina |
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of GRINA mRNA |
CTD |
PMID:16079270 |
|
NCBI chr15:76,130,917...76,134,109
Ensembl chr15:76,130,964...76,134,104
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|
G |
Grk5 |
G protein-coupled receptor kinase 5 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of GRK5 mRNA [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of GRK5 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
|
NCBI chr19:60,877,995...61,084,406
Ensembl chr19:60,878,187...61,084,406
|
|
G |
Gyg1 |
glycogenin 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of GYG1 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 3:20,176,248...20,209,228
Ensembl chr 3:20,176,248...20,209,481
|
|
G |
H19 |
H19, imprinted maternally expressed transcript |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of H19 mRNA] |
CTD |
PMID:21185374 |
|
NCBI chr 7:142,129,267...142,131,883
Ensembl chr 7:142,129,262...142,133,957
|
|
G |
H2-Ab1 |
histocompatibility 2, class II antigen A, beta 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of RT1-BB mRNA |
CTD |
PMID:16079270 |
|
NCBI chr17:34,482,201...34,488,392
Ensembl chr17:34,476,663...34,488,393
|
|
G |
H2ac8 |
H2A clustered histone 8 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of H2AC16 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr13:23,754,837...23,755,394
Ensembl chr13:23,754,691...23,755,394
|
|
G |
Hal |
histidine ammonia lyase |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of HAL mRNA |
CTD |
PMID:16079270 |
|
NCBI chr10:93,324,630...93,352,623
Ensembl chr10:93,324,630...93,355,166
|
|
G |
Hapln1 |
hyaluronan and proteoglycan link protein 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of HAPLN1 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr13:89,688,654...89,759,951
Ensembl chr13:89,687,915...89,759,771
|
|
G |
Has2 |
hyaluronan synthase 2 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of HAS2 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr15:56,529,023...56,557,942
Ensembl chr15:56,529,023...56,557,935
|
|
G |
Hba-a1 |
hemoglobin alpha, adult chain 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of HBA-A1 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr11:32,233,672...32,234,486
Ensembl chr11:32,233,511...32,234,465
|
|
G |
Hbb-bh1 |
hemoglobin Z, beta-like embryonic chain |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of HBG1 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 7:103,490,845...103,492,369
Ensembl chr 7:103,490,844...103,492,371
|
|
G |
Hbegf |
heparin-binding EGF-like growth factor |
multiple interactions decreases expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of HBEGF mRNA; [Raloxifene Hydrochloride co-treated with PX-866] results in decreased expression of HBEGF mRNA Raloxifene Hydrochloride results in decreased expression of HBEGF mRNA |
CTD |
PMID:19059307 PMID:27017931 |
|
NCBI chr18:36,637,980...36,648,858
Ensembl chr18:36,637,980...36,648,858
|
|
G |
Hbp1 |
high mobility group box transcription factor 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of HBP1 mRNA |
CTD |
PMID:16497877 |
|
NCBI chr12:31,976,449...32,000,529
Ensembl chr12:31,976,253...32,000,534
|
|
G |
Heg1 |
heart development protein with EGF-like domains 1 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of HEG1 mRNA [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of HEG1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HEG1 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr16:33,504,754...33,591,946
Ensembl chr16:33,504,740...33,591,946
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G |
Herpud1 |
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of HERPUD1 mRNA |
CTD |
PMID:16497877 |
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NCBI chr 8:95,113,057...95,121,999
Ensembl chr 8:95,113,066...95,122,005
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G |
Hey2 |
hairy/enhancer-of-split related with YRPW motif 2 |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of HEY2 mRNA] |
CTD |
PMID:21185374 |
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NCBI chr10:30,708,355...30,718,779
Ensembl chr10:30,708,355...30,718,797
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G |
Hgf |
hepatocyte growth factor |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of HGF mRNA |
CTD |
PMID:16497877 |
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NCBI chr 5:16,758,493...16,827,448
Ensembl chr 5:16,758,493...16,825,150
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G |
Hk1 |
hexokinase 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of HK1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HK1 mRNA |
CTD |
PMID:19059307 |
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NCBI chr10:62,104,634...62,215,699
Ensembl chr10:62,104,634...62,215,687
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G |
Hmcn1 |
hemicentin 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with Estradiol] results in increased expression of HMCN1 mRNA |
CTD |
PMID:21185374 |
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NCBI chr 1:150,438,251...150,869,568
Ensembl chr 1:150,438,275...150,869,186
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G |
Hmga2 |
high mobility group AT-hook 2 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of HMGA2 mRNA |
CTD |
PMID:14699072 |
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NCBI chr10:120,197,173...120,312,374
Ensembl chr10:120,197,180...120,312,374
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G |
Hmgb1 |
high mobility group box 1 |
decreases expression affects expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of HMGB1 mRNA Raloxifene Hydrochloride affects the expression of HMGB1 mRNA |
CTD |
PMID:16079270 PMID:16514628 |
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NCBI chr 5:148,983,512...148,989,867
Ensembl chr 5:148,983,512...149,121,299
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G |
Hmox1 |
heme oxygenase 1 |
multiple interactions increases expression decreases expression affects expression |
ISO |
1,10-phenanthroline inhibits the reaction [Raloxifene Hydrochloride results in increased expression of HMOX1 mRNA]; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HMOX1 mRNA; Allopurinol inhibits the reaction [Raloxifene Hydrochloride results in increased expression of HMOX1 mRNA]; Buthionine Sulfoximine promotes the reaction [Raloxifene Hydrochloride results in increased expression of HMOX1 mRNA]; Copper promotes the reaction [Raloxifene Hydrochloride results in increased expression of HMOX1 mRNA]; dimethyl sulfate inhibits the reaction [Raloxifene Hydrochloride results in increased expression of HMOX1 mRNA]; Glutathione inhibits the reaction [Raloxifene Hydrochloride results in increased expression of HMOX1 mRNA]; HMOX1 protein promotes the reaction [[Raloxifene Hydrochloride results in decreased expression of NOS2 protein] which results in decreased chemical synthesis of Nitric Oxide]; Iron promotes the reaction [Raloxifene Hydrochloride results in increased expression of HMOX1 mRNA]; MAP2K6 protein promotes the reaction [Raloxifene Hydrochloride results in increased expression of HMOX1 protein]; TEMPO inhibits the reaction [Raloxifene Hydrochloride results in increased expression of HMOX1 mRNA] Raloxifene Hydrochloride results in increased expression of HMOX1 mRNA; Raloxifene Hydrochloride results in increased expression of HMOX1 protein Raloxifene Hydrochloride results in decreased expression of HMOX1 mRNA Raloxifene Hydrochloride affects the expression of HMOX1 mRNA |
CTD |
PMID:16079270 PMID:16298037 PMID:19059307 PMID:20888885 |
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NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
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G |
Hnf4a |
hepatic nuclear factor 4, alpha |
decreases expression multiple interactions |
ISO |
Raloxifene Hydrochloride results in decreased expression of HNF4A mRNA fulvestrant inhibits the reaction [Raloxifene Hydrochloride results in decreased expression of HNF4A mRNA] |
CTD |
PMID:23184660 |
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NCBI chr 2:163,348,731...163,414,827
Ensembl chr 2:163,348,728...163,414,830
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G |
Hnrnpa2b1 |
heterogeneous nuclear ribonucleoprotein A2/B1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of HNRNPA2B1 mRNA |
CTD |
PMID:16514628 |
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NCBI chr 6:51,437,414...51,448,054
Ensembl chr 6:51,437,912...51,446,874
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G |
Hnrnph1 |
heterogeneous nuclear ribonucleoprotein H1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of HNRNPH1 mRNA |
CTD |
PMID:16514628 |
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NCBI chr11:50,266,084...50,277,355
Ensembl chr11:50,267,817...50,277,355
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G |
Hnrnpu |
heterogeneous nuclear ribonucleoprotein U |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of HNRNPU mRNA |
CTD |
PMID:16514628 |
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NCBI chr 1:178,148,673...178,170,063
Ensembl chr 1:178,148,673...178,165,362
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G |
Homer2 |
homer scaffolding protein 2 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of HOMER2 mRNA |
CTD |
PMID:14699072 |
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NCBI chr 7:81,250,229...81,356,673
Ensembl chr 7:81,250,229...81,357,275
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G |
Hoxa1 |
homeobox A1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of HOXA1 mRNA |
CTD |
PMID:16079270 |
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NCBI chr 6:52,132,573...52,135,299
Ensembl chr 6:52,132,570...52,135,297
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G |
Hpcal1 |
hippocalcin-like 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HPCAL1 mRNA |
CTD |
PMID:19059307 |
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NCBI chr12:17,740,810...17,841,943
Ensembl chr12:17,740,857...17,841,934
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G |
Hpgd |
hydroxyprostaglandin dehydrogenase 15 (NAD) |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of HPGD mRNA] |
CTD |
PMID:21185374 |
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NCBI chr 8:56,747,587...56,774,081
Ensembl chr 8:56,747,620...56,774,078
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G |
Hsd17b11 |
hydroxysteroid (17-beta) dehydrogenase 11 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with Estradiol] results in increased expression of HSD17B11 mRNA |
CTD |
PMID:21185374 |
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NCBI chr 5:104,137,631...104,169,662
Ensembl chr 5:104,137,628...104,169,785
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G |
Hsd17b4 |
hydroxysteroid (17-beta) dehydrogenase 4 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of HSD17B4 mRNA |
CTD |
PMID:16079270 |
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NCBI chr18:50,261,268...50,329,337
Ensembl chr18:50,261,268...50,329,336
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G |
Hsp90ab1 |
heat shock protein 90 alpha (cytosolic), class B member 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of HSP90AB1 mRNA |
CTD |
PMID:16514628 |
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NCBI chr17:45,878,704...45,884,187
Ensembl chr17:45,878,701...45,884,197
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G |
Hsp90b1 |
heat shock protein 90, beta (Grp94), member 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of HSP90B1 mRNA |
CTD |
PMID:16514628 |
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NCBI chr10:86,526,705...86,541,308
Ensembl chr10:86,526,073...86,541,373
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G |
Hspa1a |
heat shock protein 1A |
affects expression increases expression |
ISO |
Raloxifene Hydrochloride affects the expression of HSPA1A mRNA Raloxifene Hydrochloride results in increased expression of HSPA1A protein |
CTD |
PMID:14699072 PMID:15860553 |
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NCBI chr17:35,188,335...35,191,132
Ensembl chr17:35,188,166...35,191,132
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G |
Hspa1b |
heat shock protein 1B |
multiple interactions affects expression |
ISO |
ESR1 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of HSPA1B mRNA] Raloxifene Hydrochloride affects the expression of HSPA1B mRNA |
CTD |
PMID:14699072 |
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NCBI chr17:35,175,405...35,178,214
Ensembl chr17:35,175,412...35,178,214
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G |
Hspa4 |
heat shock protein 4 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of HSPA4 mRNA |
CTD |
PMID:16514628 |
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NCBI chr11:53,150,641...53,191,306
Ensembl chr11:53,150,641...53,191,284
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G |
Hspa8 |
heat shock protein 8 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of HSPA8 mRNA |
CTD |
PMID:16514628 |
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NCBI chr 9:40,712,572...40,716,498
Ensembl chr 9:40,712,280...40,721,383
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G |
Hspb8 |
heat shock protein 8 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HSPB8 mRNA; Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of HSPB8 mRNA] |
CTD |
PMID:19059307 PMID:21185374 |
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NCBI chr 5:116,546,550...116,560,923
Ensembl chr 5:116,546,550...116,560,923
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G |
Hspd1 |
heat shock protein 1 (chaperonin) |
decreases expression affects expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of HSPD1 mRNA Raloxifene Hydrochloride affects the expression of HSPD1 mRNA |
CTD |
PMID:16079270 PMID:16514628 |
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NCBI chr 1:55,116,992...55,127,402
Ensembl chr 1:55,116,994...55,127,402
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G |
Htr2a |
5-hydroxytryptamine (serotonin) receptor 2A |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of HTR2A mRNA Raloxifene Hydrochloride inhibits the reaction [estradiol 3-benzoate results in increased expression of HTR2A mRNA]; Raloxifene Hydrochloride inhibits the reaction [estradiol 3-benzoate results in increased expression of HTR2A protein] |
CTD |
PMID:14699072 PMID:17398000 |
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NCBI chr14:74,878,314...74,944,299
Ensembl chr14:74,878,280...74,946,934
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G |
Htr3a |
5-hydroxytryptamine (serotonin) receptor 3A |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HTR3A mRNA |
CTD |
PMID:19059307 |
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NCBI chr 9:48,810,513...48,822,451
Ensembl chr 9:48,810,513...48,822,399
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G |
Htr5a |
5-hydroxytryptamine (serotonin) receptor 5A |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of HTR5A mRNA |
CTD |
PMID:16079270 |
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NCBI chr 5:28,046,836...28,059,403
Ensembl chr 5:28,047,147...28,060,086
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G |
Icam1 |
intercellular adhesion molecule 1 |
multiple interactions |
EXP |
Raloxifene Hydrochloride affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of ICAM1 protein] |
CTD |
PMID:32828944 |
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NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113
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G |
Id1 |
inhibitor of DNA binding 1, HLH protein |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ID1 mRNA |
CTD |
PMID:14699072 |
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NCBI chr 2:152,578,171...152,579,330
Ensembl chr 2:152,578,171...152,579,330
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G |
Id4 |
inhibitor of DNA binding 4 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ID4 mRNA |
CTD |
PMID:19059307 |
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NCBI chr13:48,414,592...48,419,504
Ensembl chr13:48,414,704...48,419,502
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G |
Idh2 |
isocitrate dehydrogenase 2 (NADP+), mitochondrial |
multiple interactions affects expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of IDH2 mRNA; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of IDH2 mRNA] Raloxifene Hydrochloride affects the expression of IDH2 mRNA |
CTD |
PMID:14699072 PMID:16079270 PMID:19059307 |
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NCBI chr 7:79,744,594...79,768,356
Ensembl chr 7:79,744,594...79,765,140
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G |
Ido1 |
indoleamine 2,3-dioxygenase 1 |
multiple interactions increases expression |
EXP |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of IDO1 mRNA] Raloxifene Hydrochloride results in increased expression of IDO1 mRNA |
CTD |
PMID:18367319 |
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NCBI chr 8:25,074,148...25,086,987
Ensembl chr 8:25,074,152...25,087,025
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G |
Ier3 |
immediate early response 3 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of IER3 mRNA ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of IER3 mRNA] |
CTD |
PMID:14699072 |
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NCBI chr17:36,132,605...36,133,803
Ensembl chr17:36,132,576...36,133,815
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G |
Ifit2 |
interferon-induced protein with tetratricopeptide repeats 2 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of IFIT2 mRNA |
CTD |
PMID:14699072 |
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NCBI chr19:34,527,961...34,553,934
Ensembl chr19:34,528,094...34,553,819
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G |
Ifngr2 |
interferon gamma receptor 2 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of IFNGR2 mRNA |
CTD |
PMID:19059307 |
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NCBI chr16:91,343,947...91,360,895
Ensembl chr16:91,343,960...91,362,511
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G |
Ifrd1 |
interferon-related developmental regulator 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of IFRD1 mRNA |
CTD |
PMID:16514628 |
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NCBI chr12:40,253,128...40,273,184
Ensembl chr12:40,251,566...40,298,503
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G |
Igf1 |
insulin-like growth factor 1 |
multiple interactions decreases expression increases expression affects expression |
ISO |
Raloxifene Hydrochloride inhibits the reaction [NCOR2 protein binds to IGF1 promoter]; Raloxifene Hydrochloride promotes the reaction [CREBBP protein binds to IGF1 promoter]; Raloxifene Hydrochloride promotes the reaction [ESR1 protein binds to IGF1 promoter]; Raloxifene Hydrochloride promotes the reaction [ESR2 protein binds to IGF1 promoter]; Raloxifene Hydrochloride promotes the reaction [NCOA1 protein binds to IGF1 promoter]; Raloxifene Hydrochloride promotes the reaction [NCOA2 protein binds to IGF1 promoter]; Raloxifene Hydrochloride promotes the reaction [NCOA3 protein binds to IGF1 promoter] Raloxifene Hydrochloride results in decreased expression of IGF1 mRNA; Raloxifene Hydrochloride results in decreased expression of IGF1 protein Raloxifene Hydrochloride results in increased expression of IGF1 mRNA Raloxifene Hydrochloride affects the expression of IGF1 mRNA |
CTD |
PMID:15762036 PMID:15978972 PMID:16912660 PMID:17645796 PMID:17872375 PMID:19350480 More...
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NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904
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G |
Igf2 |
insulin-like growth factor 2 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of IGF2 mRNA |
CTD |
PMID:15576828 |
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NCBI chr 7:142,204,505...142,220,566
Ensembl chr 7:142,204,503...142,220,553
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G |
Igfbp3 |
insulin-like growth factor binding protein 3 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of IGFBP3 protein |
CTD |
PMID:15855258 PMID:16912660 |
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NCBI chr11:7,156,086...7,165,498
Ensembl chr11:7,156,086...7,163,923
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G |
Igfbp4 |
insulin-like growth factor binding protein 4 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of IGFBP4 mRNA |
CTD |
PMID:14699072 |
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NCBI chr11:98,930,820...98,943,481
Ensembl chr11:98,932,070...98,945,218
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G |
Igfbp6 |
insulin-like growth factor binding protein 6 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of IGFBP6 mRNA |
CTD |
PMID:15576828 |
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NCBI chr15:102,052,621...102,057,947
Ensembl chr15:102,052,797...102,057,946
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G |
Il10ra |
interleukin 10 receptor, alpha |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of IL10RA mRNA |
CTD |
PMID:16497877 |
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NCBI chr 9:45,165,135...45,180,447
Ensembl chr 9:45,165,135...45,180,447
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G |
Il11 |
interleukin 11 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with PX-866] results in decreased expression of IL11 mRNA |
CTD |
PMID:26660119 |
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NCBI chr 7:4,775,372...4,785,877
Ensembl chr 7:4,775,372...4,785,858
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G |
Il12a |
interleukin 12a |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of IL12A mRNA |
CTD |
PMID:19429434 |
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NCBI chr 3:68,597,977...68,605,881
Ensembl chr 3:68,597,977...68,605,880
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G |
Il13ra1 |
interleukin 13 receptor, alpha 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of IL13RA1 mRNA |
CTD |
PMID:22217510 |
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NCBI chr X:35,375,761...35,434,915
Ensembl chr X:35,375,763...35,434,912
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G |
Il1b |
interleukin 1 beta |
multiple interactions |
EXP ISO |
[Raloxifene Hydrochloride co-treated with IL1B protein] results in increased expression of PTGDS mRNA; Fulvestrant inhibits the reaction [Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased expression of CCL20 protein]]; Fulvestrant inhibits the reaction [Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased phosphorylation of and affects the localization of RELA protein]]; Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased expression of BCL3 mRNA]; Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased expression of CCL20 protein]; Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased expression of CISH mRNA]; Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased expression of CXCL5 mRNA]; Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased expression of PLK3 mRNA]; Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased phosphorylation of and affects the localization of RELA protein] Fulvestrant inhibits the reaction [Raloxifene Hydrochloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of IL1B mRNA]]; Raloxifene Hydrochloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of IL1B mRNA]; Raloxifene Hydrochloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased secretion of IL1B protein] |
CTD |
PMID:12072388 PMID:24722370 PMID:25305410 |
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NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
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G |
Il1r1 |
interleukin 1 receptor, type I |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in decreased expression of IL1R1 mRNA] |
CTD |
PMID:21185374 |
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NCBI chr 1:40,261,651...40,355,361
Ensembl chr 1:40,264,240...40,356,417
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G |
Il1rap |
interleukin 1 receptor accessory protein |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of IL1RAP mRNA |
CTD |
PMID:14699072 |
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NCBI chr16:26,400,259...26,548,878
Ensembl chr16:26,400,454...26,548,867
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G |
Il4 |
interleukin 4 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with Bexarotene] affects the reaction [Azoxymethane affects the expression of IL4 mRNA] Raloxifene Hydrochloride inhibits the reaction [IL4 protein results in increased phosphorylation of STAT3 protein] |
CTD |
PMID:24080207 PMID:24456369 |
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NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
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G |
Il4ra |
interleukin 4 receptor, alpha |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of IL4R mRNA |
CTD |
PMID:14699072 |
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NCBI chr 7:125,151,443...125,178,646
Ensembl chr 7:125,151,292...125,178,646
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G |
Il6 |
interleukin 6 |
decreases expression multiple interactions decreases secretion |
ISO EXP |
Raloxifene Hydrochloride results in decreased expression of IL6 mRNA; Raloxifene Hydrochloride results in decreased expression of IL6 protein Raloxifene Hydrochloride affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of IL6 protein]; Raloxifene Hydrochloride affects the reaction [[APOE protein affects the susceptibility to IL6 protein] which affects the phosphorylation of STAT3 protein]; Raloxifene Hydrochloride inhibits the reaction [IL6 protein results in increased phosphorylation of and affects the localization of STAT3 protein]; Raloxifene Hydrochloride inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]; Raloxifene Hydrochloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of IL6 mRNA]; Raloxifene Hydrochloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of IL6 protein]; Raloxifene Hydrochloride inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 mRNA]; Raloxifene Hydrochloride inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] Raloxifene Hydrochloride inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]; Raloxifene Hydrochloride inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] ESR1 protein affects the reaction [Raloxifene Hydrochloride results in decreased secretion of IL6 protein]; Raloxifene Hydrochloride inhibits the reaction [[IL6R protein co-treated with IL6 protein] results in increased phosphorylation of STAT3 protein]; Raloxifene Hydrochloride inhibits the reaction [IL6 protein results in increased phosphorylation of and affects the localization of STAT3 protein]; Raloxifene Hydrochloride inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]; Raloxifene Hydrochloride inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] |
CTD |
PMID:15579764 PMID:15762036 PMID:15953991 PMID:16298037 PMID:19533603 PMID:27576059 PMID:28430601 PMID:28711499 PMID:32828944 PMID:32940862 PMID:32947957 More...
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NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
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G |
Il6ra |
interleukin 6 receptor, alpha |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [[IL6R protein co-treated with IL6 protein] results in increased phosphorylation of STAT3 protein] |
CTD |
PMID:32828944 |
|
NCBI chr 3:89,776,631...89,820,503
Ensembl chr 3:89,771,366...89,820,503
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G |
Il6st |
interleukin 6 signal transducer |
affects binding |
ISO |
Raloxifene Hydrochloride binds to IL6ST protein |
CTD |
PMID:24456369 PMID:32940862 |
|
NCBI chr13:112,600,604...112,643,394
Ensembl chr13:112,600,604...112,646,620
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G |
Il7r |
interleukin 7 receptor |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of IL7R mRNA |
CTD |
PMID:14699072 |
|
NCBI chr15:9,505,880...9,530,270
Ensembl chr15:9,505,874...9,530,262
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G |
Ilrun |
inflammation and lipid regulator with UBA-like and NBR1-like domains |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of ILRUN mRNA |
CTD |
PMID:16514628 |
|
NCBI chr17:27,970,206...28,039,516
Ensembl chr17:27,970,209...28,039,622
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G |
Inhba |
inhibin beta-A |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of INHBA mRNA |
CTD |
PMID:19059307 |
|
NCBI chr13:16,178,841...16,206,194
Ensembl chr13:16,186,436...16,206,206
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G |
Inpp4b |
inositol polyphosphate-4-phosphatase, type II |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of INPP4B mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 8:82,068,895...82,865,553
Ensembl chr 8:82,069,185...82,854,543
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G |
Inpp5a |
inositol polyphosphate-5-phosphatase A |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of INPP5A mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 7:138,969,025...139,159,568
Ensembl chr 7:138,969,025...139,159,568
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G |
Ins1 |
insulin I |
multiple interactions |
EXP |
IWR-1 compound inhibits the reaction [Raloxifene Hydrochloride inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CTNNB1 protein]]; IWR-1 compound inhibits the reaction [Raloxifene Hydrochloride inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CEBPA protein]]; IWR-1 compound inhibits the reaction [Raloxifene Hydrochloride inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of PPARG protein]]; Raloxifene Hydrochloride affects the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of FABP4 protein]; Raloxifene Hydrochloride inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CTNNB1 protein]; Raloxifene Hydrochloride inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CEBPA protein]; Raloxifene Hydrochloride inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of PPARG protein] |
CTD |
PMID:31470850 |
|
NCBI chr19:52,252,735...52,253,453
Ensembl chr19:52,252,735...52,253,914
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G |
Insig1 |
insulin induced gene 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of INSIG1 mRNA |
CTD |
PMID:16497877 |
|
NCBI chr 5:28,276,410...28,283,660
Ensembl chr 5:28,276,361...28,283,660
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G |
Iqgap1 |
IQ motif containing GTPase activating protein 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of IQGAP1 mRNA |
CTD |
PMID:16514628 |
|
NCBI chr 7:80,361,331...80,453,288
Ensembl chr 7:80,361,331...80,475,722
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G |
Irf7 |
interferon regulatory factor 7 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of IRF7 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 7:140,843,096...140,846,412
Ensembl chr 7:140,842,619...140,846,394
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G |
Isg20 |
interferon-stimulated protein |
multiple interactions affects expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of ISG20 mRNA Raloxifene Hydrochloride affects the expression of ISG20 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr 7:78,561,136...78,570,144
Ensembl chr 7:78,563,172...78,570,144
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G |
Itgb1 |
integrin beta 1 (fibronectin receptor beta) |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of ITGB1 mRNA |
CTD |
PMID:12154049 PMID:19429434 |
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NCBI chr 8:129,412,135...129,460,060
Ensembl chr 8:129,412,135...129,459,681
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G |
Itgb3 |
integrin beta 3 |
increases expression |
EXP |
Raloxifene Hydrochloride results in increased expression of ITGB3 mRNA |
CTD |
PMID:26603317 |
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NCBI chr11:104,498,826...104,561,302
Ensembl chr11:104,498,826...104,561,302
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G |
Itpr3 |
inositol 1,4,5-triphosphate receptor 3 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ITPR3 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr17:27,275,976...27,341,197
Ensembl chr17:27,276,278...27,341,197
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G |
Ivl |
involucrin |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of IVL mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of IVL mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr 3:92,478,206...92,481,097
Ensembl chr 3:92,478,209...92,481,042
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G |
Jag1 |
jagged 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of JAG1 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 2:136,923,371...136,958,440
Ensembl chr 2:136,923,376...136,958,564
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G |
Jak2 |
Janus kinase 2 |
multiple interactions decreases expression |
ISO |
Raloxifene Hydrochloride promotes the reaction [GH1 protein results in increased phosphorylation of JAK2 protein] Raloxifene Hydrochloride results in decreased expression of JAK2 mRNA |
CTD |
PMID:17272397 PMID:26865669 |
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NCBI chr19:29,229,006...29,290,495
Ensembl chr19:29,229,228...29,290,480
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G |
Jun |
jun proto-oncogene |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of JUN mRNA |
CTD |
PMID:12154049 |
|
NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459
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G |
Kazn |
kazrin, periplakin interacting protein |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of KAZN mRNA |
CTD |
PMID:19059307 |
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NCBI chr 4:141,829,701...142,801,231
Ensembl chr 4:141,829,701...142,205,056
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G |
Kcnd3 |
potassium voltage-gated channel, Shal-related family, member 3 |
multiple interactions decreases expression decreases activity |
ISO |
[KCNIP2 protein co-treated with Raloxifene Hydrochloride] results in decreased activity of KCND3 protein Raloxifene Hydrochloride results in decreased expression of KCND3 mRNA Raloxifene Hydrochloride promotes the reaction [Fulvestrant results in decreased activity of KCND3 protein] Raloxifene Hydrochloride results in decreased activity of KCND3 protein |
CTD |
PMID:25231973 |
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NCBI chr 3:105,359,206...105,581,318
Ensembl chr 3:105,359,646...105,581,318
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G |
Kcne1 |
potassium voltage-gated channel, Isk-related subfamily, member 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of KCNE1 mRNA |
CTD |
PMID:15576828 |
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NCBI chr16:92,142,889...92,156,356
Ensembl chr16:92,142,870...92,156,356
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G |
Kcnh5 |
potassium voltage-gated channel, subfamily H (eag-related), member 5 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of KCNH5 mRNA |
CTD |
PMID:16079270 |
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NCBI chr12:74,943,991...75,224,625
Ensembl chr12:74,943,994...75,224,106
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G |
Kcnip2 |
Kv channel-interacting protein 2 |
multiple interactions |
ISO |
[KCNIP2 protein co-treated with Raloxifene Hydrochloride] results in decreased activity of KCND3 protein |
CTD |
PMID:25231973 |
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NCBI chr19:45,780,785...45,804,948
Ensembl chr19:45,780,278...45,804,500
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G |
Kcnn4 |
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 |
multiple interactions affects expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of KCNN4 mRNA Raloxifene Hydrochloride affects the expression of KCNN4 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr 7:24,069,750...24,084,635
Ensembl chr 7:24,069,688...24,086,115
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G |
Kctd12 |
potassium channel tetramerisation domain containing 12 |
multiple interactions affects expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of KCTD12 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of KCTD12 mRNA Raloxifene Hydrochloride affects the expression of KCTD12 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr14:103,214,017...103,220,073
Ensembl chr14:103,214,017...103,220,073
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G |
Kif20a |
kinesin family member 20A |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of KIF20A mRNA |
CTD |
PMID:16514628 |
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NCBI chr18:34,757,677...34,766,330
Ensembl chr18:34,757,666...34,766,330
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G |
Kif3c |
kinesin family member 3C |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of KIF3C mRNA |
CTD |
PMID:19059307 |
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NCBI chr12:3,415,132...3,456,494
Ensembl chr12:3,415,132...3,456,494
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G |
Kiss1 |
KiSS-1 metastasis-suppressor |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of KISS1 mRNA |
CTD |
PMID:27395752 |
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NCBI chr 1:133,249,625...133,257,460
Ensembl chr 1:133,237,565...133,257,460 Ensembl chr 1:133,237,565...133,257,460
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G |
Klf10 |
Kruppel-like transcription factor 10 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of KLF10 mRNA |
CTD |
PMID:14699072 |
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NCBI chr15:38,291,702...38,300,950
Ensembl chr15:38,291,707...38,300,950
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G |
Klf6 |
Kruppel-like transcription factor 6 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of KLF6 mRNA |
CTD |
PMID:15576828 |
|
NCBI chr13:5,911,488...5,920,392
Ensembl chr13:5,911,481...5,920,393
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G |
Klhl24 |
kelch-like 24 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of KLHL24 mRNA |
CTD |
PMID:19429434 |
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NCBI chr16:19,916,286...19,947,976
Ensembl chr16:19,916,292...19,947,971
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G |
Klrc1 |
killer cell lectin-like receptor subfamily C, member 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of KLRC1 mRNA |
CTD |
PMID:17962382 |
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NCBI chr 6:129,642,978...129,659,815
Ensembl chr 6:129,642,978...129,655,936
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G |
Klrc2 |
killer cell lectin-like receptor subfamily C, member 2 |
multiple interactions affects expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of KLRC2 mRNA; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of KLRC2 mRNA]; ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of KLRC2 mRNA] Raloxifene Hydrochloride affects the expression of KLRC2 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr 6:129,626,565...129,637,700
Ensembl chr 6:129,624,459...129,637,652
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G |
Klrc3 |
killer cell lectin-like receptor subfamily C, member 3 |
multiple interactions increases expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of KLRC3 mRNA; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of KLRC3 mRNA]; Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of KLRC3 mRNA]; Raloxifene Hydrochloride promotes the reaction [ESR1 protein binds to KLRC3 gene]; Raloxifene Hydrochloride promotes the reaction [NCOA3 protein binds to KLRC3 gene] |
CTD |
PMID:17395694 PMID:19059307 |
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NCBI chr 6:129,613,226...129,620,474
Ensembl chr 6:129,616,027...129,620,300
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G |
Klrk1 |
killer cell lectin-like receptor subfamily K, member 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of KLRK1 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 6:129,587,286...129,600,863
Ensembl chr 6:129,587,286...129,600,827
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G |
Kpna2 |
karyopherin subunit alpha 2 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of KPNA2 mRNA |
CTD |
PMID:16514628 |
|
NCBI chr11:106,879,455...106,890,351
Ensembl chr11:106,879,455...106,890,367
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G |
Kpnb1 |
karyopherin subunit beta 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of KPNB1 mRNA |
CTD |
PMID:16514628 |
|
NCBI chr11:97,050,536...97,078,718
Ensembl chr11:97,050,540...97,078,707
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G |
Krt17 |
keratin 17 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of KRT17 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr11:100,147,041...100,151,855
Ensembl chr11:100,147,043...100,151,855
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G |
Krt34 |
keratin 34 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of KRT34 mRNA |
CTD |
PMID:19059307 |
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NCBI chr11:99,928,173...99,932,380
Ensembl chr11:99,928,173...99,932,380
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G |
L3mbtl1 |
L3MBTL1 histone methyl-lysine binding protein |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of L3MBTL1 mRNA |
CTD |
PMID:19429434 |
|
NCBI chr 2:162,784,260...162,819,726
Ensembl chr 2:162,785,392...162,816,442
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G |
Lamb1 |
laminin B1 |
multiple interactions |
EXP |
[APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of LAMB1 mRNA |
CTD |
PMID:24431404 |
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NCBI chr12:31,315,230...31,379,643
Ensembl chr12:31,315,233...31,379,643
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G |
Lamc1 |
laminin, gamma 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of LAMC1 mRNA |
CTD |
PMID:14699072 |
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NCBI chr 1:153,094,668...153,208,532
Ensembl chr 1:153,094,668...153,208,532
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G |
Lbh |
limb-bud and heart |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of LBH mRNA |
CTD |
PMID:19059307 |
|
NCBI chr17:73,225,300...73,248,941
Ensembl chr17:73,225,300...73,248,942
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G |
Lcn2 |
lipocalin 2 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of LCN2 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 2:32,274,649...32,277,751
Ensembl chr 2:32,274,645...32,278,264
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G |
Ldlr |
low density lipoprotein receptor |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of LDLR mRNA |
CTD |
PMID:16497877 |
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NCBI chr 9:21,634,872...21,661,215
Ensembl chr 9:21,634,779...21,661,215
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G |
Ldlrad4 |
low density lipoprotein receptor class A domain containing 4 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of LDLRAD4 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr18:68,065,345...68,393,621
Ensembl chr18:68,066,328...68,401,701
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G |
Lepr |
leptin receptor |
affects expression |
ISO |
Raloxifene decreases Lepr protein expression in adipose tissue at 7 weeks and increases it at 22 weeks |
RGD |
PMID:15059958 |
RGD:1581837 |
NCBI chr 4:101,574,393...101,676,375
Ensembl chr 4:101,574,601...101,672,549
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G |
Lgr5 |
leucine rich repeat containing G protein coupled receptor 5 |
multiple interactions |
EXP |
[APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of LGR5 mRNA; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of LGR5 protein |
CTD |
PMID:24431404 |
|
NCBI chr10:115,286,219...115,423,685
Ensembl chr10:115,286,216...115,423,685
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G |
Lhb |
luteinizing hormone beta |
multiple interactions decreases secretion |
ISO |
Raloxifene Hydrochloride inhibits the reaction [estradiol 3-benzoate results in increased secretion of LHB protein] Raloxifene Hydrochloride results in decreased secretion of LHB protein |
CTD |
PMID:17398000 PMID:27395752 |
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NCBI chr 7:45,070,370...45,071,278
Ensembl chr 7:45,070,244...45,071,321
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G |
Lif |
leukemia inhibitory factor |
decreases expression multiple interactions |
ISO EXP |
Raloxifene Hydrochloride results in decreased expression of LIF mRNA [Raloxifene Hydrochloride co-treated with PX-866] results in decreased expression of LIF mRNA |
CTD |
PMID:26603317 PMID:27017931 |
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NCBI chr11:4,207,587...4,222,514
Ensembl chr11:4,207,557...4,222,514
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G |
Limch1 |
LIM and calponin homology domains 1 |
multiple interactions |
ISO |
Raloxifene Hydrochloride promotes the reaction [Estradiol results in increased expression of LIMCH1 mRNA] |
CTD |
PMID:21185374 |
|
NCBI chr 5:66,903,232...67,214,502
Ensembl chr 5:66,903,170...67,214,501
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G |
Liph |
lipase, member H |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with Estradiol] results in increased expression of LIPH mRNA |
CTD |
PMID:21185374 |
|
NCBI chr16:21,772,567...21,814,408
Ensembl chr16:21,772,567...21,814,413
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G |
Lmcd1 |
LIM and cysteine-rich domains 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of LMCD1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of LMCD1 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 6:112,250,747...112,307,384
Ensembl chr 6:112,250,719...112,307,386
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G |
Lmnb2 |
lamin B2 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of LMNB2 mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of LMNB2 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
|
NCBI chr10:80,737,197...80,754,079
Ensembl chr10:80,737,037...80,754,079
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G |
Lox |
lysyl oxidase |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of LOX mRNA |
CTD |
PMID:16079270 |
|
NCBI chr18:52,649,132...52,662,939
Ensembl chr18:52,649,139...52,662,939
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G |
Lpl |
lipoprotein lipase |
multiple interactions increases expression |
ISO EXP |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of LPL mRNA Raloxifene Hydrochloride results in increased expression of LPL mRNA |
CTD |
PMID:16643890 PMID:19059307 |
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NCBI chr 8:69,333,207...69,359,584
Ensembl chr 8:69,333,143...69,360,100
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G |
Lrig1 |
leucine-rich repeats and immunoglobulin-like domains 1 |
multiple interactions affects expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of LRIG1 mRNA Raloxifene Hydrochloride affects the expression of LRIG1 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
|
NCBI chr 6:94,581,510...94,677,205
Ensembl chr 6:94,581,510...94,677,139
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G |
Lrrc20 |
leucine rich repeat containing 20 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of LRRC20 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr10:61,311,579...61,418,570
Ensembl chr10:61,311,580...61,418,570
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G |
Ltb |
lymphotoxin B |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of LTB mRNA |
CTD |
PMID:19429434 |
|
NCBI chr17:35,413,483...35,415,281
Ensembl chr17:35,413,415...35,415,296
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G |
Ltbp1 |
latent transforming growth factor beta binding protein 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of LTBP1 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr17:75,312,475...75,699,507
Ensembl chr17:75,312,563...75,699,507
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G |
Lum |
lumican |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of LUM mRNA |
CTD |
PMID:14699072 |
|
NCBI chr10:97,401,363...97,408,565
Ensembl chr10:97,400,990...97,408,565
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G |
Lyn |
LYN proto-oncogene, Src family tyrosine kinase |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with Estradiol] results in increased expression of LYN mRNA |
CTD |
PMID:21185374 |
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NCBI chr 4:3,676,865...3,791,613
Ensembl chr 4:3,678,115...3,813,122
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G |
Lysmd4 |
LysM, putative peptidoglycan-binding, domain containing 4 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of LYSMD4 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 7:66,872,292...66,878,216
Ensembl chr 7:66,872,292...66,957,078
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G |
Macroh2a1 |
macroH2A.1 histone |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of MACROH2A1 mRNA |
CTD |
PMID:16079270 |
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NCBI chr13:56,221,435...56,283,439
Ensembl chr13:56,221,432...56,284,174
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G |
Maf |
MAF bZIP transcription factor |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of MAF mRNA |
CTD |
PMID:19429434 |
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NCBI chr 8:116,429,992...116,433,633
Ensembl chr 8:116,409,681...116,434,533
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G |
Maff |
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian) |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MAFF mRNA |
CTD |
PMID:19059307 |
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NCBI chr15:79,230,813...79,243,278
Ensembl chr15:79,230,821...79,243,276
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G |
Man2a2 |
mannosidase 2, alpha 2 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of MAN2A2 mRNA |
CTD |
PMID:14699072 |
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NCBI chr 7:79,998,843...80,021,222
Ensembl chr 7:79,998,845...80,021,123
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G |
Map1lc3b |
microtubule-associated protein 1 light chain 3 beta |
increases lipidation multiple interactions |
ISO |
Raloxifene Hydrochloride results in increased lipidation of MAP1LC3B protein [Raloxifene Hydrochloride co-treated with Oxygen deficiency] results in increased lipidation of MAP1LC3B protein |
CTD |
PMID:33203845 |
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NCBI chr 8:122,317,177...122,325,499
Ensembl chr 8:122,317,100...122,325,499
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G |
Map2k3 |
mitogen-activated protein kinase kinase 3 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of MAP2K3 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr11:60,822,880...60,843,637
Ensembl chr11:60,822,859...60,843,637
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G |
Map2k6 |
mitogen-activated protein kinase kinase 6 |
multiple interactions |
ISO |
MAP2K6 protein promotes the reaction [Raloxifene Hydrochloride results in increased expression of HMOX1 protein] |
CTD |
PMID:20888885 |
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NCBI chr11:110,289,928...110,416,348
Ensembl chr11:110,289,948...110,416,348
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G |
Map3k11 |
mitogen-activated protein kinase kinase kinase 11 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of MAP3K11 mRNA |
CTD |
PMID:12154049 |
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NCBI chr19:5,738,764...5,752,893
Ensembl chr19:5,738,770...5,752,893
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G |
Map3k20 |
mitogen-activated protein kinase kinase kinase 20 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of MAP3K20 mRNA |
CTD |
PMID:19429434 |
|
NCBI chr 2:72,115,970...72,272,954
Ensembl chr 2:72,115,981...72,272,954
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G |
Map3k5 |
mitogen-activated protein kinase kinase kinase 5 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MAP3K5 mRNA |
CTD |
PMID:19059307 |
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NCBI chr10:19,809,847...20,018,496
Ensembl chr10:19,810,218...20,018,499
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G |
Map3k8 |
mitogen-activated protein kinase kinase kinase 8 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MAP3K8 mRNA |
CTD |
PMID:19059307 |
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NCBI chr18:4,331,325...4,352,978
Ensembl chr18:4,331,327...4,353,015
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G |
Mapk1 |
mitogen-activated protein kinase 1 |
multiple interactions increases phosphorylation |
EXP ISO |
U 0126 inhibits the reaction [Raloxifene Hydrochloride results in increased phosphorylation of MAPK1 protein] 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [Raloxifene Hydrochloride results in increased phosphorylation of MAPK1 protein]; Raloxifene Hydrochloride inhibits the reaction [Methylmercury Compounds results in increased activity of MAPK1 protein]; sotrastaurin inhibits the reaction [Raloxifene Hydrochloride results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [Raloxifene Hydrochloride results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:15712295 PMID:16798746 PMID:17174166 PMID:20945400 PMID:24782323 PMID:26200092 More...
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NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
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G |
Mapk14 |
mitogen-activated protein kinase 14 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of MAPK14 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr17:28,910,316...28,967,379
Ensembl chr17:28,910,303...28,967,380
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G |
Mapk3 |
mitogen-activated protein kinase 3 |
multiple interactions increases phosphorylation |
ISO EXP |
4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [Raloxifene Hydrochloride results in increased phosphorylation of MAPK3 protein]; Raloxifene Hydrochloride inhibits the reaction [Methylmercury Compounds results in increased activity of MAPK3 protein]; sotrastaurin inhibits the reaction [Raloxifene Hydrochloride results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [Raloxifene Hydrochloride results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:15712295 PMID:16798746 PMID:17174166 PMID:20945400 PMID:24782323 PMID:26200092 More...
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NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
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G |
Mapkapk2 |
MAP kinase-activated protein kinase 2 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MAPKAPK2 mRNA |
CTD |
PMID:19059307 |
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NCBI chr 1:130,981,437...131,025,580
Ensembl chr 1:130,981,437...131,025,563
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G |
Marcksl1 |
MARCKS-like 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of MARCKSL1 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 4:129,407,374...129,409,774
Ensembl chr 4:129,407,374...129,409,778
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G |
Matr3 |
matrin 3 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of MATR3 mRNA |
CTD |
PMID:16514628 |
|
NCBI chr18:35,686,462...35,724,526
Ensembl chr18:35,695,191...35,726,888
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G |
Mbnl2 |
muscleblind like splicing factor 2 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MBNL2 mRNA |
CTD |
PMID:19059307 |
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NCBI chr14:120,513,077...120,669,110
Ensembl chr14:120,513,081...120,669,109
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G |
Mctp1 |
multiple C2 domains, transmembrane 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of MCTP1 mRNA |
CTD |
PMID:19429434 |
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NCBI chr13:76,530,481...77,181,403
Ensembl chr13:76,532,259...77,179,929
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G |
Mdfic |
MyoD family inhibitor domain containing |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of MDFIC mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MDFIC mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr 6:15,720,660...15,802,168
Ensembl chr 6:15,720,660...15,802,168
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G |
Mdm2 |
transformed mouse 3T3 cell double minute 2 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with PX-866] results in decreased phosphorylation of MDM2 protein |
CTD |
PMID:27017931 |
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NCBI chr10:117,524,780...117,546,663
Ensembl chr10:117,524,780...117,546,663
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G |
Mef2a |
myocyte enhancer factor 2A |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MEF2A mRNA |
CTD |
PMID:19059307 |
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NCBI chr 7:66,880,911...67,026,435
Ensembl chr 7:66,880,911...67,022,606
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G |
Mfap5 |
microfibrillar associated protein 5 |
multiple interactions affects expression |
ISO |
ESR1 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of MFAP5 mRNA] Raloxifene Hydrochloride affects the expression of MFAP5 mRNA |
CTD |
PMID:14699072 |
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NCBI chr 6:122,490,543...122,506,249
Ensembl chr 6:122,482,804...122,506,249
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G |
Mgp |
matrix Gla protein |
multiple interactions decreases expression |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of MGP mRNA] Raloxifene Hydrochloride results in decreased expression of MGP mRNA |
CTD |
PMID:16514628 PMID:21185374 |
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NCBI chr 6:136,849,433...136,852,821
Ensembl chr 6:136,849,433...136,852,821
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G |
Mical2 |
microtubule associated monooxygenase, calponin and LIM domain containing 2 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of MICAL2 mRNA |
CTD |
PMID:26865669 |
|
NCBI chr 7:111,825,032...112,012,311
Ensembl chr 7:111,825,063...112,012,313
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G |
Mid1 |
midline 1 |
multiple interactions |
ISO |
Raloxifene Hydrochloride promotes the reaction [Estradiol results in increased expression of MID1 mRNA] |
CTD |
PMID:21185374 |
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NCBI chr X:168,468,178...168,773,692
Ensembl chr X:168,468,195...168,773,794
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G |
Mir491 |
microRNA 491 |
multiple interactions |
ISO |
[[MIR491 results in decreased activity of UGT1A1 protein] which results in decreased metabolism of Raloxifene Hydrochloride] which results in decreased abundance of Raloxifene Hydrochloride metabolite; [MIR491 results in decreased activity of UGT1A1 protein] which results in decreased abundance of Raloxifene Hydrochloride metabolite; [MIR491 results in decreased activity of UGT1A1 protein] which results in decreased metabolism of Raloxifene Hydrochloride |
CTD |
PMID:24399855 |
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NCBI chr 4:88,040,277...88,040,362
Ensembl chr 4:88,040,277...88,040,362
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G |
Mki67 |
antigen identified by monoclonal antibody Ki 67 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of MKI67 protein |
CTD |
PMID:11535548 |
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NCBI chr 7:135,291,513...135,318,286
Ensembl chr 7:135,291,513...135,318,090
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G |
Mmd2 |
monocyte to macrophage differentiation-associated 2 |
increases expression |
EXP |
Raloxifene Hydrochloride results in increased expression of MMD2 mRNA |
CTD |
PMID:22841776 |
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NCBI chr 5:142,549,229...142,594,886
Ensembl chr 5:142,548,113...142,594,555
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G |
Mmp12 |
matrix metallopeptidase 12 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of MMP12 mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MMP12 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr 9:7,344,397...7,360,461
Ensembl chr 9:7,344,381...7,369,499
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G |
Mmp13 |
matrix metallopeptidase 13 |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Decitabine results in increased expression of MMP13 mRNA] |
CTD |
PMID:23385821 |
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NCBI chr 9:7,272,514...7,283,333
Ensembl chr 9:7,272,514...7,283,331
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G |
Mmp2 |
matrix metallopeptidase 2 |
affects expression multiple interactions |
ISO EXP |
Raloxifene Hydrochloride affects the expression of MMP2 mRNA 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Raloxifene Hydrochloride inhibits the reaction [Streptozocin results in decreased secretion of MMP2 protein]]; ESR2 protein affects the reaction [Raloxifene Hydrochloride inhibits the reaction [Streptozocin results in decreased secretion of MMP2 protein]]; Raloxifene Hydrochloride inhibits the reaction [Streptozocin results in decreased expression of MMP2 mRNA]; Raloxifene Hydrochloride inhibits the reaction [Streptozocin results in decreased secretion of MMP2 protein] |
CTD |
PMID:16079270 PMID:23471663 |
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NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048
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G |
Mmp3 |
matrix metallopeptidase 3 |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Decitabine results in increased expression of MMP3 mRNA] |
CTD |
PMID:23385821 |
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NCBI chr 9:7,445,845...7,455,975
Ensembl chr 9:7,445,822...7,455,975
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G |
Mmp9 |
matrix metallopeptidase 9 |
decreases activity decreases expression increases expression multiple interactions |
ISO EXP |
Raloxifene Hydrochloride results in decreased activity of MMP9 protein Raloxifene Hydrochloride results in decreased expression of MMP9 mRNA Raloxifene Hydrochloride results in increased expression of MMP9 mRNA [9,10-Dimethyl-1,2-benzanthracene co-treated with Raloxifene Hydrochloride co-treated with Fluoxetine] affects the expression of MMP9 protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with Raloxifene Hydrochloride] affects the expression of MMP9 protein |
CTD |
PMID:17582780 PMID:22841776 PMID:31332895 |
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NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
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G |
Mn1 |
meningioma 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MN1 mRNA |
CTD |
PMID:19059307 |
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NCBI chr 5:111,565,145...111,604,890
Ensembl chr 5:111,565,228...111,604,899
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G |
Mpo |
myeloperoxidase |
multiple interactions |
ISO |
Carrageenan inhibits the reaction [Raloxifene Hydrochloride results in increased activity of MPO protein] |
CTD |
PMID:15860553 |
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NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239
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G |
Mpped2 |
metallophosphoesterase domain containing 2 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MPPED2 mRNA |
CTD |
PMID:19059307 |
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NCBI chr 2:106,523,526...106,699,684
Ensembl chr 2:106,523,614...106,698,701
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G |
Mr1 |
major histocompatibility complex, class I-related |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of MR1 mRNA |
CTD |
PMID:19429434 |
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NCBI chr 1:155,003,620...155,022,560
Ensembl chr 1:155,003,023...155,022,560
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G |
Mrpl33 |
mitochondrial ribosomal protein L33 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of MRPL33 mRNA |
CTD |
PMID:14699072 |
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NCBI chr 5:31,771,295...31,779,988
Ensembl chr 5:31,754,279...31,821,728
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G |
Msmb |
beta-microseminoprotein |
multiple interactions affects expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of MSMB mRNA; ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of MSMB mRNA] Raloxifene Hydrochloride affects the expression of MSMB mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr14:31,863,980...31,880,284
Ensembl chr14:31,863,980...31,880,327
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G |
Mst1 |
macrophage stimulating 1 (hepatocyte growth factor-like) |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of MST1 mRNA |
CTD |
PMID:19429434 |
|
NCBI chr 9:107,957,607...107,962,226
Ensembl chr 9:107,957,635...107,962,202
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G |
Mt2 |
metallothionein 2 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of MT2A mRNA |
CTD |
PMID:20945400 |
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NCBI chr 8:94,899,246...94,900,195
Ensembl chr 8:94,899,292...94,900,196
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G |
Mthfr |
methylenetetrahydrofolate reductase |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of MTHFR mRNA |
CTD |
PMID:15849065 |
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NCBI chr 4:148,123,534...148,144,019
Ensembl chr 4:148,123,534...148,144,008
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G |
Mtor |
mechanistic target of rapamycin kinase |
increases phosphorylation |
ISO |
Raloxifene Hydrochloride results in increased phosphorylation of MTOR protein |
CTD |
PMID:25537862 |
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NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140
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G |
Muc1 |
mucin 1, transmembrane |
increases expression affects expression |
ISO |
Raloxifene Hydrochloride results in increased expression of MUC1 protein Raloxifene Hydrochloride affects the expression of MUC1 mRNA |
CTD |
PMID:16012748 PMID:16079270 |
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NCBI chr 3:89,136,363...89,140,688
Ensembl chr 3:89,136,364...89,140,688
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G |
Myb |
myeloblastosis oncogene |
multiple interactions decreases expression |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of MYB mRNA] Raloxifene Hydrochloride results in decreased expression of MYB mRNA |
CTD |
PMID:21185374 PMID:26865669 |
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NCBI chr10:21,000,829...21,036,883
Ensembl chr10:21,000,834...21,036,883
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G |
Mybl1 |
myeloblastosis oncogene-like 1 |
multiple interactions decreases expression |
ISO |
[Raloxifene Hydrochloride co-treated with Estradiol] results in decreased expression of MYBL1 mRNA Raloxifene Hydrochloride results in decreased expression of MYBL1 mRNA |
CTD |
PMID:21185374 PMID:26865669 |
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NCBI chr 1:9,737,632...9,770,664
Ensembl chr 1:9,737,640...9,770,434
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G |
Myc |
myelocytomatosis oncogene |
multiple interactions decreases expression increases expression |
ISO |
GPER1 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of MYC mRNA]; Raloxifene Hydrochloride inhibits the reaction [[NRG1 protein co-treated with Estradiol] results in increased expression of MYC protein] Raloxifene Hydrochloride results in decreased expression of MYC mRNA; Raloxifene Hydrochloride results in decreased expression of MYC protein |
CTD |
PMID:16497877 PMID:20945400 PMID:22453024 PMID:26502914 |
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NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223
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G |
Myl9 |
myosin, light polypeptide 9, regulatory |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of MYL9 mRNA |
CTD |
PMID:16079270 |
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NCBI chr 2:156,617,373...156,623,578
Ensembl chr 2:156,617,340...156,623,578
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G |
Myo10 |
myosin X |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of MYO10 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr15:25,622,636...25,813,759
Ensembl chr15:25,622,611...25,813,759
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G |
Myod1 |
myogenic differentiation 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of MYOD1 mRNA |
CTD |
PMID:19432593 |
|
NCBI chr 7:46,025,898...46,028,516
Ensembl chr 7:46,025,898...46,028,523
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G |
Myt1l |
myelin transcription factor 1-like |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MYT1L mRNA |
CTD |
PMID:19059307 |
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NCBI chr12:29,578,375...29,973,215
Ensembl chr12:29,578,383...29,973,212
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G |
Nab1 |
Ngfi-A binding protein 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of NAB1 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 1:52,494,146...52,539,553
Ensembl chr 1:52,496,453...52,539,838
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G |
Nars1 |
asparaginyl-tRNA synthetase 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of NARS1 mRNA |
CTD |
PMID:16514628 |
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NCBI chr18:64,632,726...64,649,586
Ensembl chr18:64,632,718...64,649,723
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G |
Nav2 |
neuron navigator 2 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NAV2 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 7:48,608,796...49,259,838
Ensembl chr 7:48,558,464...49,259,838
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G |
Nbl1 |
NBL1, DAN family BMP antagonist |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of NBL1 mRNA |
CTD |
PMID:15576828 |
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NCBI chr 4:138,809,602...138,820,437
Ensembl chr 4:138,809,595...138,820,304
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G |
Ncaph |
non-SMC condensin I complex, subunit H |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of NCAPH mRNA |
CTD |
PMID:16514628 |
|
NCBI chr 2:126,945,729...126,975,857
Ensembl chr 2:126,945,729...126,975,874
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G |
Ncf2 |
neutrophil cytosolic factor 2 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of NCF2 mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NCF2 mRNA; ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of NCF2 mRNA] |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr 1:152,675,904...152,712,743
Ensembl chr 1:152,675,945...152,712,742
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G |
Ncl |
nucleolin |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of NCL mRNA |
CTD |
PMID:16514628 |
|
NCBI chr 1:86,272,441...86,287,177
Ensembl chr 1:86,272,441...86,287,122
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G |
Ncoa1 |
nuclear receptor coactivator 1 |
multiple interactions increases expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NCOA1 mRNA; Raloxifene Hydrochloride promotes the reaction [NCOA1 protein binds to IGF1 promoter] Raloxifene Hydrochloride results in increased expression of NCOA1 mRNA |
CTD |
PMID:17872375 PMID:19059307 PMID:19432593 |
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NCBI chr12:4,297,362...4,569,452
Ensembl chr12:4,297,362...4,527,182
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G |
Ncoa2 |
nuclear receptor coactivator 2 |
multiple interactions increases expression |
ISO |
Raloxifene Hydrochloride promotes the reaction [NCOA2 protein binds to IGF1 promoter]; Raloxifene Hydrochloride promotes the reaction [NCOA2 protein binds to PTGS2 promoter] Raloxifene Hydrochloride results in increased expression of NCOA2 protein |
CTD |
PMID:16739346 PMID:17872375 |
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NCBI chr 1:13,209,329...13,444,451
Ensembl chr 1:13,209,329...13,444,307
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G |
Ncoa3 |
nuclear receptor coactivator 3 |
multiple interactions |
ISO |
Raloxifene Hydrochloride promotes the reaction [NCOA3 protein binds to IGF1 promoter]; Raloxifene Hydrochloride promotes the reaction [NCOA3 protein binds to KLRC3 gene]; Raloxifene Hydrochloride promotes the reaction [NCOA3 protein binds to PTGS2 promoter] |
CTD |
PMID:17395694 PMID:17872375 |
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NCBI chr 2:165,834,557...165,915,162
Ensembl chr 2:165,834,545...165,915,162
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G |
Ncoa4 |
nuclear receptor coactivator 4 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of NCOA4 mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NCOA4 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr14:31,881,884...31,901,210
Ensembl chr14:31,881,822...31,901,812
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G |
Ncor2 |
nuclear receptor co-repressor 2 |
multiple interactions decreases expression |
ISO |
Raloxifene Hydrochloride inhibits the reaction [NCOR2 protein binds to IGF1 promoter]; Raloxifene Hydrochloride inhibits the reaction [NCOR2 protein binds to PTGS2 promoter] Raloxifene Hydrochloride results in decreased expression of NCOR2 mRNA |
CTD |
PMID:17872375 PMID:19432593 |
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NCBI chr 5:125,094,217...125,256,302
Ensembl chr 5:125,094,217...125,256,283
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G |
Ndrg4 |
N-myc downstream regulated gene 4 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NDRG4 mRNA |
CTD |
PMID:19059307 |
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NCBI chr 8:96,403,602...96,441,584
Ensembl chr 8:96,403,608...96,441,747
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G |
Ndufa2 |
NADH:ubiquinone oxidoreductase subunit A2 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of NDUFA2 mRNA |
CTD |
PMID:14699072 |
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NCBI chr18:36,875,385...36,877,640
Ensembl chr18:36,875,385...36,877,610
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G |
Nectin1 |
nectin cell adhesion molecule 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of NECTIN1 mRNA |
CTD |
PMID:16079270 |
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NCBI chr 9:43,655,251...43,718,758
Ensembl chr 9:43,655,281...43,743,955
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G |
Nefl |
neurofilament, light polypeptide |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of NEFL mRNA |
CTD |
PMID:14699072 |
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NCBI chr14:68,321,312...68,326,544
Ensembl chr14:68,321,312...68,326,544
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G |
Nek7 |
NIMA (never in mitosis gene a)-related expressed kinase 7 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of NEK7 mRNA |
CTD |
PMID:14699072 |
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NCBI chr 1:138,411,575...138,547,481
Ensembl chr 1:138,410,613...138,547,879
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G |
Nf1 |
neurofibromin 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of NF1 mRNA |
CTD |
PMID:19429434 |
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NCBI chr11:79,223,541...79,472,435
Ensembl chr11:79,230,519...79,472,438
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G |
Nfatc1 |
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NFATC1 mRNA |
CTD |
PMID:19059307 |
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NCBI chr18:80,649,418...80,756,286
Ensembl chr18:80,649,420...80,756,286
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G |
Nfe2l1 |
nuclear factor, erythroid derived 2,-like 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of NFE2L1 mRNA |
CTD |
PMID:16497877 |
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NCBI chr11:96,708,239...96,720,810
Ensembl chr11:96,708,240...96,720,794
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G |
Nfil3 |
nuclear factor, interleukin 3, regulated |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of NFIL3 mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NFIL3 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr13:53,121,245...53,136,914
Ensembl chr13:53,121,245...53,135,109
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G |
Nfkb1 |
nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 |
multiple interactions |
ISO |
Raloxifene Hydrochloride promotes the reaction [NFKB1 protein binds to SLC1A2 promoter] |
CTD |
PMID:24782323 |
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NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308
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G |
Nfkbia |
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha |
multiple interactions decreases expression affects expression |
ISO EXP |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NFKBIA mRNA Raloxifene Hydrochloride results in decreased expression of NFKBIA mRNA Raloxifene Hydrochloride affects the expression of NFKBIA mRNA Raloxifene Hydrochloride inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]; SFRP5 protein affects the reaction [Raloxifene Hydrochloride inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]] |
CTD |
PMID:14699072 PMID:16298037 PMID:19059307 PMID:31470850 |
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NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432
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G |
Nfkbie |
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of NFKBIE mRNA |
CTD |
PMID:19059307 |
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NCBI chr17:45,866,626...45,874,095
Ensembl chr17:45,866,629...45,874,095
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G |
Nherf1 |
NHERF family PDZ scaffold protein 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of NHERF1 mRNA |
CTD |
PMID:14699072 |
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NCBI chr11:115,054,138...115,072,009
Ensembl chr11:115,054,167...115,072,007
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G |
Ninj1 |
ninjurin 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NINJ1 mRNA |
CTD |
PMID:19059307 |
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NCBI chr13:49,341,005...49,349,727
Ensembl chr13:49,340,961...49,349,720
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G |
Nlrp3 |
NLR family, pyrin domain containing 3 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of NLRP3 mRNA |
CTD |
PMID:19059307 |
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NCBI chr11:59,432,395...59,457,781
Ensembl chr11:59,432,394...59,457,782
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G |
Nme6 |
NME/NM23 nucleoside diphosphate kinase 6 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of NME6 mRNA |
CTD |
PMID:16079270 |
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NCBI chr 9:109,661,830...109,672,042
Ensembl chr 9:109,661,817...109,672,184
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G |
Nmrk1 |
nicotinamide riboside kinase 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of NMRK1 mRNA |
CTD |
PMID:26865669 |
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NCBI chr19:18,609,380...18,629,555
Ensembl chr19:18,609,314...18,629,792
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G |
Nos2 |
nitric oxide synthase 2, inducible |
multiple interactions decreases expression |
ISO |
[Raloxifene Hydrochloride co-treated with 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid] results in increased expression of NOS2 protein; [Raloxifene Hydrochloride results in decreased expression of NOS2 protein] which results in decreased chemical synthesis of Nitric Oxide; Cycloheximide inhibits the reaction [[Raloxifene Hydrochloride co-treated with 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid] results in increased expression of NOS2 protein]; Dactinomycin inhibits the reaction [[Raloxifene Hydrochloride co-treated with 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid] results in increased expression of NOS2 protein]; Fulvestrant inhibits the reaction [[Raloxifene Hydrochloride co-treated with 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid] results in increased expression of NOS2 protein]; HMOX1 protein promotes the reaction [[Raloxifene Hydrochloride results in decreased expression of NOS2 protein] which results in decreased chemical synthesis of Nitric Oxide]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Raloxifene Hydrochloride co-treated with 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid] results in increased expression of NOS2 protein]; XDH protein promotes the reaction [[Raloxifene Hydrochloride results in decreased expression of NOS2 protein] which results in decreased chemical synthesis of Nitric Oxide] Carrageenan inhibits the reaction [Raloxifene Hydrochloride results in increased expression of NOS2 protein] |
CTD |
PMID:15860553 PMID:20888885 PMID:28138957 |
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NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
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G |
Nos3 |
nitric oxide synthase 3, endothelial cell |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of NOS3 mRNA |
CTD |
PMID:11779577 |
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NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472
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G |
Notch3 |
notch 3 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of NOTCH3 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr17:32,339,794...32,385,869
Ensembl chr17:32,339,794...32,385,826
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G |
Npm1 |
nucleophosmin 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of NPM1 mRNA |
CTD |
PMID:16514628 |
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NCBI chr11:33,102,498...33,114,143
Ensembl chr11:33,102,287...33,113,206
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G |
Npr2 |
natriuretic peptide receptor 2 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of NPR2 mRNA [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of NPR2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NPR2 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr 4:43,629,015...43,651,437
Ensembl chr 4:43,631,935...43,651,244
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G |
Npy1r |
neuropeptide Y receptor Y1 |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of NPY1R mRNA] |
CTD |
PMID:21185374 |
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NCBI chr 8:67,149,595...67,159,452
Ensembl chr 8:67,149,844...67,159,444
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G |
Nqo1 |
NAD(P)H dehydrogenase, quinone 1 |
increases expression multiple interactions |
EXP ISO |
Raloxifene Hydrochloride results in increased expression of NQO1 protein ARNT protein affects the reaction [Raloxifene Hydrochloride results in increased expression of NQO1 protein] |
CTD |
PMID:24481452 |
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NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838
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G |
Nr1d1 |
nuclear receptor subfamily 1, group D, member 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NR1D1 mRNA |
CTD |
PMID:19059307 |
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NCBI chr11:98,658,758...98,666,233
Ensembl chr11:98,658,758...98,666,159
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G |
Nr2f6 |
nuclear receptor subfamily 2, group F, member 6 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of NR2F6 mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NR2F6 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr 8:71,826,762...71,834,593
Ensembl chr 8:71,826,767...71,834,604
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G |
Nr3c1 |
nuclear receptor subfamily 3, group C, member 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of NR3C1 mRNA |
CTD |
PMID:19059307 |
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NCBI chr18:39,543,598...39,652,485
Ensembl chr18:39,543,598...39,652,474
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G |
Nr4a1 |
nuclear receptor subfamily 4, group A, member 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of NR4A1 mRNA |
CTD |
PMID:16514628 |
|
NCBI chr15:101,151,783...101,172,676
Ensembl chr15:101,152,150...101,172,676
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G |
Nr4a3 |
nuclear receptor subfamily 4, group A, member 3 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of NR4A3 mRNA |
CTD |
PMID:19059307 |
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NCBI chr 4:48,045,098...48,086,446
Ensembl chr 4:48,045,153...48,086,447
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G |
Nrep |
neuronal regeneration related protein |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of NREP mRNA |
CTD |
PMID:14699072 |
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NCBI chr18:33,570,072...33,597,444
Ensembl chr18:33,570,072...33,597,082
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G |
Nrf1 |
nuclear respiratory factor 1 |
multiple interactions increases expression |
ISO |
fulvestrant inhibits the reaction [Raloxifene Hydrochloride results in increased expression of NRF1 mRNA]; Vehicle Emissions inhibits the reaction [Raloxifene Hydrochloride results in increased expression of NRF1 mRNA] |
CTD |
PMID:22105178 |
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NCBI chr 6:30,047,984...30,153,462
Ensembl chr 6:30,047,987...30,153,457
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G |
Nrg1 |
neuregulin 1 |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [[NRG1 protein co-treated with Estradiol] results in increased expression of MYC protein] |
CTD |
PMID:26502914 |
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NCBI chr 8:32,299,493...33,381,858
Ensembl chr 8:32,304,579...33,374,825 Ensembl chr 8:32,304,579...33,374,825
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G |
Nrg2 |
neuregulin 2 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of NRG2 mRNA |
CTD |
PMID:15849065 |
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NCBI chr18:36,147,634...36,332,754
Ensembl chr18:36,150,705...36,330,433
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G |
Nuak1 |
NUAK family, SNF1-like kinase, 1 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of NUAK1 mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NUAK1 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr10:84,206,764...84,282,028
Ensembl chr10:84,206,769...84,276,461
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G |
Nup160 |
nucleoporin 160 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of NUP160 mRNA |
CTD |
PMID:16497877 |
|
NCBI chr 2:90,504,405...90,570,217
Ensembl chr 2:90,507,559...90,566,672
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G |
Nus1 |
NUS1 dehydrodolichyl diphosphate synthase subunit |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of NUS1 mRNA |
CTD |
PMID:16514628 |
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NCBI chr10:52,293,643...52,316,288
Ensembl chr10:52,293,643...52,316,279
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G |
Nxf1 |
nuclear RNA export factor 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of NXF1 mRNA |
CTD |
PMID:16079270 |
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NCBI chr19:8,734,467...8,748,274
Ensembl chr19:8,734,437...8,748,286
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G |
Ocln |
occludin |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of OCLN mRNA |
CTD |
PMID:19059307 |
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NCBI chr13:100,633,012...100,689,226
Ensembl chr13:100,633,015...100,689,226
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G |
Olfm1 |
olfactomedin 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of OLFM1 mRNA |
CTD |
PMID:26865669 |
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NCBI chr 2:28,083,105...28,120,748
Ensembl chr 2:28,083,004...28,120,748
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G |
Olfml2a |
olfactomedin-like 2A |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of OLFML2A mRNA |
CTD |
PMID:14699072 |
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NCBI chr 2:38,821,992...38,850,597
Ensembl chr 2:38,821,990...38,853,765
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G |
Or10al6 |
olfactory receptor family 10 subfamily AL member 6 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of OR10AL6 mRNA |
CTD |
PMID:16079270 |
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NCBI chr17:38,079,533...38,083,511
Ensembl chr17:38,079,498...38,084,640
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G |
Osbpl3 |
oxysterol binding protein-like 3 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of OSBPL3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of OSBPL3 mRNA |
CTD |
PMID:19059307 |
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NCBI chr 6:50,270,307...50,433,334
Ensembl chr 6:50,270,310...50,433,181
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G |
Osbpl7 |
oxysterol binding protein-like 7 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of OSBPL7 mRNA |
CTD |
PMID:19429434 |
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NCBI chr11:96,941,459...96,959,730
Ensembl chr11:96,941,454...96,959,730
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G |
Otub2 |
OTU domain, ubiquitin aldehyde binding 2 |
multiple interactions decreases expression |
ISO EXP |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of OTUB2 mRNA Raloxifene Hydrochloride results in decreased expression of OTUB2 mRNA |
CTD |
PMID:19059307 PMID:33269387 |
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NCBI chr12:103,343,244...103,372,609
Ensembl chr12:103,354,941...103,372,609
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G |
Otud1 |
OTU domain containing 1 |
multiple interactions |
EXP |
[SOD1 protein mutant form affects the susceptibility to Raloxifene Hydrochloride] which results in increased expression of OTUD1 mRNA |
CTD |
PMID:33269387 |
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NCBI chr 2:19,662,542...19,666,090
Ensembl chr 2:19,662,563...19,665,394
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G |
Otud3 |
OTU domain containing 3 |
multiple interactions decreases expression |
EXP |
[SOD1 protein mutant form affects the susceptibility to Raloxifene Hydrochloride] which results in decreased expression of OTUD3 mRNA Raloxifene Hydrochloride results in decreased expression of OTUD3 mRNA |
CTD |
PMID:33269387 |
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NCBI chr 4:138,618,374...138,641,322
Ensembl chr 4:138,622,690...138,641,256
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G |
Otud5 |
OTU domain containing 5 |
decreases expression |
EXP |
Raloxifene Hydrochloride results in decreased expression of OTUD5 mRNA |
CTD |
PMID:33269387 |
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NCBI chr X:7,705,852...7,742,861
Ensembl chr X:7,707,603...7,742,865
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G |
Otud7a |
OTU domain containing 7A |
decreases expression |
EXP |
Raloxifene Hydrochloride results in decreased expression of OTUD7A mRNA |
CTD |
PMID:33269387 |
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NCBI chr 7:63,094,493...63,415,980
Ensembl chr 7:63,094,499...63,408,776
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G |
Otud7b |
OTU domain containing 7B |
increases expression multiple interactions |
EXP |
Raloxifene Hydrochloride results in increased expression of OTUD7B mRNA [SOD1 protein mutant form affects the susceptibility to Raloxifene Hydrochloride] which results in increased expression of OTUD7B mRNA |
CTD |
PMID:33269387 |
|
NCBI chr 3:96,011,759...96,068,446
Ensembl chr 3:96,011,839...96,068,446
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G |
P2ry14 |
purinergic receptor P2Y, G-protein coupled, 14 |
multiple interactions |
EXP |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of P2RY14 mRNA] |
CTD |
PMID:18367319 |
|
NCBI chr 3:59,022,044...59,060,913
Ensembl chr 3:59,021,276...59,061,039
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G |
Palld |
palladin, cytoskeletal associated protein |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of PALLD mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 8:61,964,465...62,355,741
Ensembl chr 8:61,964,467...62,355,724
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G |
Papola |
poly (A) polymerase alpha |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of PAPOLA mRNA |
CTD |
PMID:16079270 |
|
NCBI chr12:105,750,926...105,805,208
Ensembl chr12:105,750,953...105,805,203
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G |
Pappa |
pregnancy-associated plasma protein A |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of PAPPA mRNA |
CTD |
PMID:19429434 |
|
NCBI chr 4:65,041,993...65,276,776
Ensembl chr 4:65,042,411...65,275,746
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G |
Park7 |
Parkinson disease (autosomal recessive, early onset) 7 |
increases expression |
EXP |
Raloxifene Hydrochloride results in increased expression of PARK7 mRNA |
CTD |
PMID:33269387 |
|
NCBI chr 4:150,981,590...150,994,378
Ensembl chr 4:150,981,590...150,998,894
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G |
Parp1 |
poly (ADP-ribose) polymerase family, member 1 |
increases cleavage multiple interactions |
ISO |
Raloxifene Hydrochloride results in increased cleavage of PARP1 protein [ESR1 protein co-treated with ESR2 protein] affects the reaction [Raloxifene Hydrochloride results in increased cleavage of PARP1 protein] |
CTD |
PMID:22965848 |
|
NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
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G |
Pawr |
PRKC, apoptosis, WT1, regulator |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of PAWR mRNA; Raloxifene Hydrochloride results in increased expression of PAWR protein |
CTD |
PMID:20945400 |
|
NCBI chr10:108,168,050...108,250,708
Ensembl chr10:108,167,982...108,250,101
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G |
Pax5 |
paired box 5 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of PAX5 mRNA |
CTD |
PMID:12154049 |
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NCBI chr 4:44,524,748...44,710,694
Ensembl chr 4:44,524,757...44,710,487
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G |
Pcdh7 |
protocadherin 7 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of PCDH7 mRNA |
CTD |
PMID:19059307 |
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NCBI chr 5:57,873,487...58,290,578
Ensembl chr 5:57,875,309...58,290,572
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G |
Pcdhga3 |
protocadherin gamma subfamily A, 3 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of PCDHGA3 mRNA |
CTD |
PMID:19429434 |
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NCBI chr18:37,807,388...37,974,926
Ensembl chr18:37,807,360...37,974,926
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G |
Pclaf |
PCNA clamp associated factor |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of PCLAF mRNA |
CTD |
PMID:16514628 |
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NCBI chr 9:65,797,605...65,810,833
Ensembl chr 9:65,797,519...65,810,548
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G |
Pcna |
proliferating cell nuclear antigen |
increases expression decreases expression affects expression multiple interactions |
ISO EXP |
Raloxifene Hydrochloride results in increased expression of PCNA protein Raloxifene Hydrochloride results in decreased expression of PCNA protein Raloxifene Hydrochloride affects the expression of PCNA protein [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of PCNA protein |
CTD |
PMID:15731164 PMID:16009171 PMID:17220163 PMID:24431404 |
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NCBI chr 2:132,091,206...132,095,100
Ensembl chr 2:132,091,082...132,095,234
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G |
Pcolce |
procollagen C-endopeptidase enhancer protein |
affects expression increases expression |
ISO |
Raloxifene Hydrochloride affects the expression of PCOLCE mRNA Raloxifene Hydrochloride results in increased expression of PCOLCE mRNA |
CTD |
PMID:15576828 PMID:16079270 |
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NCBI chr 5:137,603,369...137,609,666
Ensembl chr 5:137,603,365...137,612,046
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G |
Pctp |
phosphatidylcholine transfer protein |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PCTP mRNA |
CTD |
PMID:19059307 |
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NCBI chr11:89,873,370...89,893,720
Ensembl chr11:89,873,491...89,893,720
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G |
Pdcd5 |
programmed cell death 5 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of PDCD5 mRNA |
CTD |
PMID:16202921 |
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NCBI chr 7:35,341,410...35,346,907
Ensembl chr 7:35,341,407...35,346,946
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G |
Pde3b |
phosphodiesterase 3B, cGMP-inhibited |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of PDE3B mRNA |
CTD |
PMID:19429434 |
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NCBI chr 7:114,014,388...114,137,173
Ensembl chr 7:114,014,516...114,138,486
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Pde4d |
phosphodiesterase 4D, cAMP specific |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of PDE4D mRNA |
CTD |
PMID:16497877 |
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NCBI chr13:108,790,711...110,092,503
Ensembl chr13:108,586,482...110,089,995
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Pde5a |
phosphodiesterase 5A, cGMP-specific |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of PDE5A mRNA |
CTD |
PMID:19429434 |
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NCBI chr 3:122,522,822...122,653,023
Ensembl chr 3:122,522,596...122,653,023
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G |
Pdgfra |
platelet derived growth factor receptor, alpha polypeptide |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of PDGFRA mRNA |
CTD |
PMID:14699072 |
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NCBI chr 5:75,311,988...75,358,867
Ensembl chr 5:75,312,953...75,358,876
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G |
Pdgfrb |
platelet derived growth factor receptor, beta polypeptide |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of PDGFRB mRNA |
CTD |
PMID:14699072 |
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NCBI chr18:61,178,194...61,218,139
Ensembl chr18:61,178,222...61,218,133
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G |
Pdlim3 |
PDZ and LIM domain 3 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PDLIM3 mRNA |
CTD |
PMID:19059307 |
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NCBI chr 8:46,338,524...46,372,672
Ensembl chr 8:46,338,498...46,372,585
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G |
Pdp1 |
pyruvate dehydrogenase phosphatase catalytic subunit 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of PDP1 mRNA |
CTD |
PMID:19059307 |
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NCBI chr 4:11,958,183...11,966,450
Ensembl chr 4:11,958,184...11,966,452
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G |
Pdyn |
prodynorphin |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of PDYN mRNA |
CTD |
PMID:16079270 |
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NCBI chr 2:129,528,469...129,541,858
Ensembl chr 2:129,528,485...129,541,764
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G |
Pdzk1 |
PDZ domain containing 1 |
multiple interactions decreases expression |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of PDZK1 mRNA] Raloxifene Hydrochloride results in decreased expression of PDZK1 mRNA |
CTD |
PMID:21185374 PMID:26865669 |
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NCBI chr 3:96,736,772...96,778,242
Ensembl chr 3:96,736,600...96,778,242
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G |
Per2 |
period circadian clock 2 |
multiple interactions |
EXP |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in decreased expression of PER2 mRNA] |
CTD |
PMID:18728223 |
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NCBI chr 1:91,343,699...91,387,028
Ensembl chr 1:91,343,704...91,387,046
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G |
Pex5 |
peroxisomal biogenesis factor 5 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of PEX5 mRNA |
CTD |
PMID:16079270 |
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NCBI chr 6:124,373,774...124,392,878
Ensembl chr 6:124,373,775...124,392,026
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G |
Pfkfb3 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of PFKFB3 mRNA |
CTD |
PMID:19059307 |
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NCBI chr 2:11,476,241...11,558,882
Ensembl chr 2:11,476,244...11,558,888
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G |
Pgr |
progesterone receptor |
multiple interactions increases expression decreases expression |
ISO EXP |
[Raloxifene Hydrochloride co-treated with Estradiol] results in increased expression of PGR mRNA; [trichostatin A co-treated with Raloxifene Hydrochloride] results in decreased expression of PGR mRNA; Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of PGR mRNA]; trichostatin A inhibits the reaction [[Raloxifene Hydrochloride co-treated with Estradiol] results in increased expression of PGR mRNA] Raloxifene Hydrochloride results in increased expression of PGR protein Raloxifene Hydrochloride results in decreased expression of PGR mRNA; Raloxifene Hydrochloride results in decreased expression of PGR protein [Estradiol co-treated with Raloxifene Hydrochloride] results in increased expression of PGR mRNA; Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of PGR mRNA] |
CTD |
PMID:11867264 PMID:16837883 PMID:16973256 PMID:21185374 PMID:22476901 PMID:26865669 PMID:26879975 More...
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NCBI chr 9:8,890,017...8,968,612
Ensembl chr 9:8,899,834...8,968,612
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G |
Phc2 |
polyhomeotic 2 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PHC2 mRNA |
CTD |
PMID:19059307 |
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NCBI chr 4:128,548,448...128,646,674
Ensembl chr 4:128,548,495...128,646,674
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G |
Phf11d |
PHD finger protein 11D |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PHF11 mRNA |
CTD |
PMID:19059307 |
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NCBI chr14:59,584,646...59,608,004
Ensembl chr14:59,584,856...59,602,919
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G |
Phlpp1 |
PH domain and leucine rich repeat protein phosphatase 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of PHLPP mRNA |
CTD |
PMID:16079270 |
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NCBI chr 1:106,099,599...106,321,975
Ensembl chr 1:106,099,482...106,321,980
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G |
Pias3 |
protein inhibitor of activated STAT 3 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of PIAS3 mRNA |
CTD |
PMID:16079270 |
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NCBI chr 3:96,603,679...96,613,386
Ensembl chr 3:96,603,700...96,613,386
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G |
Pign |
phosphatidylinositol glycan anchor biosynthesis, class N |
increases expression |
EXP |
Raloxifene Hydrochloride results in increased expression of PIGN mRNA |
CTD |
PMID:22841776 |
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NCBI chr 1:105,446,147...105,591,466
Ensembl chr 1:105,446,147...105,591,402
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G |
Pigr |
polymeric immunoglobulin receptor |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of PIGR mRNA |
CTD |
PMID:16079270 |
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NCBI chr 1:130,754,421...130,779,986
Ensembl chr 1:130,754,421...130,779,986
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G |
Pik3r3 |
phosphoinositide-3-kinase regulatory subunit 3 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of PIK3R3 mRNA |
CTD |
PMID:26865669 |
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NCBI chr 4:116,078,593...116,160,253
Ensembl chr 4:116,078,815...116,160,253 Ensembl chr 4:116,078,815...116,160,253
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G |
Pim1 |
proviral integration site 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of PIM1 mRNA |
CTD |
PMID:14699072 |
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NCBI chr17:29,709,759...29,715,085
Ensembl chr17:29,709,727...29,715,086
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G |
Pitpnc1 |
phosphatidylinositol transfer protein, cytoplasmic 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PITPNC1 mRNA |
CTD |
PMID:19059307 |
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NCBI chr11:107,098,718...107,361,546
Ensembl chr11:107,098,718...107,361,525
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G |
Pla2g10 |
phospholipase A2, group X |
multiple interactions |
ISO |
Raloxifene Hydrochloride promotes the reaction [Estradiol results in increased expression of PLA2G10 mRNA] |
CTD |
PMID:21185374 |
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NCBI chr16:13,532,921...13,548,863
Ensembl chr16:13,532,921...13,548,847
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G |
Pla2g7 |
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of PLA2G7 mRNA |
CTD |
PMID:19429434 |
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NCBI chr17:43,879,009...43,923,093
Ensembl chr17:43,878,989...43,923,092
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G |
Plat |
plasminogen activator, tissue |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of PLAT protein |
CTD |
PMID:16167916 |
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NCBI chr 8:23,247,655...23,272,864
Ensembl chr 8:23,247,743...23,272,860
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G |
Plau |
plasminogen activator, urokinase |
multiple interactions decreases expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of PLAU mRNA Raloxifene Hydrochloride results in decreased expression of PLAU protein |
CTD |
PMID:16277677 PMID:19059307 |
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NCBI chr14:20,886,730...20,893,456
Ensembl chr14:20,886,728...20,893,453
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G |
Plaur |
plasminogen activator, urokinase receptor |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of PLAUR mRNA; Raloxifene Hydrochloride results in decreased expression of PLAUR protein |
CTD |
PMID:16277677 PMID:26865669 |
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NCBI chr 7:24,161,857...24,175,393
Ensembl chr 7:24,161,909...24,175,393
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G |
Plekhf2 |
pleckstrin homology domain containing, family F (with FYVE domain) member 2 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of PLEKHF2 mRNA |
CTD |
PMID:26865669 |
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NCBI chr 4:10,988,662...11,007,619
Ensembl chr 4:10,988,662...11,007,927
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G |
Plekhs1 |
pleckstrin homology domain containing, family S member 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with Estradiol] results in increased expression of PLEKHS1 mRNA |
CTD |
PMID:21185374 |
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NCBI chr19:56,445,705...56,475,161
Ensembl chr19:56,450,072...56,475,184
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G |
Plk3 |
polo like kinase 3 |
multiple interactions |
EXP |
Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased expression of PLK3 mRNA] |
CTD |
PMID:12072388 |
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NCBI chr 4:116,985,852...116,991,244
Ensembl chr 4:116,985,852...116,991,160
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G |
Plpp1 |
phospholipid phosphatase 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of PLPP1 mRNA |
CTD |
PMID:16079270 |
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NCBI chr13:112,937,311...113,004,428
Ensembl chr13:112,937,326...113,004,428
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G |
Plpp3 |
phospholipid phosphatase 3 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of PLPP3 mRNA ESR1 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of PLPP3 mRNA] |
CTD |
PMID:14699072 |
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NCBI chr 4:105,014,544...105,089,964
Ensembl chr 4:105,014,544...105,089,961
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G |
Plxnd1 |
plexin D1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of PLXND1 mRNA |
CTD |
PMID:19429434 |
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NCBI chr 6:115,931,772...115,972,300
Ensembl chr 6:115,931,772...115,971,966
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G |
Pmaip1 |
phorbol-12-myristate-13-acetate-induced protein 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of PMAIP1 mRNA |
CTD |
PMID:16497877 |
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NCBI chr18:66,591,675...66,598,629
Ensembl chr18:66,591,604...66,598,636
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G |
Pmp22 |
peripheral myelin protein 22 |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in decreased expression of PMP22 mRNA] |
CTD |
PMID:21185374 |
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NCBI chr11:63,019,808...63,050,373
Ensembl chr11:63,019,808...63,050,373
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G |
Pms2 |
PMS1 homolog2, mismatch repair system component |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of PMS2 mRNA |
CTD |
PMID:16202921 |
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NCBI chr 5:143,846,379...143,922,538
Ensembl chr 5:143,846,782...143,870,786 Ensembl chr 5:143,846,782...143,870,786
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G |
Podxl |
podocalyxin-like |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of PODXL mRNA |
CTD |
PMID:14699072 |
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NCBI chr 6:31,496,428...31,540,872
Ensembl chr 6:31,496,423...31,540,916
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G |
Polm |
polymerase (DNA directed), mu |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of POLM mRNA |
CTD |
PMID:16497877 |
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NCBI chr11:5,777,860...5,788,831
Ensembl chr11:5,777,860...5,788,016
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G |
Polr2b |
polymerase (RNA) II (DNA directed) polypeptide B |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of POLR2B mRNA |
CTD |
PMID:16514628 |
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NCBI chr 5:77,458,331...77,497,175
Ensembl chr 5:77,457,994...77,497,171
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G |
Postn |
periostin, osteoblast specific factor |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of POSTN mRNA; Raloxifene Hydrochloride results in decreased expression of POSTN protein |
CTD |
PMID:32947957 |
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NCBI chr 3:54,266,688...54,298,462
Ensembl chr 3:54,268,530...54,298,458
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G |
Pparg |
peroxisome proliferator activated receptor gamma |
multiple interactions |
EXP |
IWR-1 compound inhibits the reaction [Raloxifene Hydrochloride inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of PPARG protein]]; Raloxifene Hydrochloride inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of PPARG protein] |
CTD |
PMID:31470850 |
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NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360
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G |
Ppm1d |
protein phosphatase 1D magnesium-dependent, delta isoform |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of PPM1D mRNA |
CTD |
PMID:16514628 |
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NCBI chr11:85,202,080...85,237,897
Ensembl chr11:85,202,070...85,237,892
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