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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:raloxifene
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Accession:CHEBI:8772 term browser browse the term
Definition:A member of the class of 1-benzothiophenes that is 1-benzothiophene in which the hydrogens at positions 2, 3, and 6 have been replaced by p-hydroxyphenyl, p-[2-(piperidin-1-yl)ethoxy]benzoyl, and hydroxy groups, respectively.
Synonyms:exact_synonym: [6-hydroxy-2-(4-hydroxyphenyl)-1-benzothien-3-yl][4-(2-piperidin-1-ylethoxy)phenyl]methanone
 related_synonym: (2-(4-Hydroxyphenyl)-6-hydroxybenzo(b)thien-3-yl)(4-(2-(1-piperidinyl)ethoxy)phenyl)methanone;   Formula=C28H27NO4S;   InChI=1S/C28H27NO4S/c30-21-8-4-20(5-9-21)28-26(24-13-10-22(31)18-25(24)34-28)27(32)19-6-11-23(12-7-19)33-17-16-29-14-2-1-3-15-29/h4-13,18,30-31H,1-3,14-17H2;   InChIKey=GZUITABIAKMVPG-UHFFFAOYSA-N;   LY 139481;   SMILES=S1C(=C(C2=C1C=C(O)C=C2)C(=O)C3=CC=C(OCCN4CCCCC4)C=C3)C5=CC=C(O)C=C5;   raloxifeno;   raloxifenum
 alt_id: CHEBI:45355
 xref: Beilstein:4890356;   CAS:84449-90-1;   DrugBank:DB00481;   Drug_Central:2351;   KEGG:C07228;   KEGG:D08465;   LINCS:LSM-3425
 xref_mesh: MESH:D020849
 xref: PDBeChem:RAL;   Patent:EP62503;   Patent:US4418068;   Wikipedia:Raloxifene
 cyclic_relationship: is_conjugate_base_of CHEBI:90191



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raloxifene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aatk apoptosis-associated tyrosine kinase increases expression EXP Raloxifene Hydrochloride results in increased expression of AATK mRNA CTD PMID:15576828 NCBI chr10:105,290,752...105,327,219
Ensembl chr10:105,291,585...105,327,112
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A decreases expression
multiple interactions
affects activity
ISO Raloxifene Hydrochloride results in decreased expression of ABCB1 mRNA; Raloxifene Hydrochloride results in decreased expression of ABCB1 protein
[Cyclosporine co-treated with Raloxifene Hydrochloride] results in decreased expression of ABCB1 mRNA; [Cyclosporine co-treated with Raloxifene Hydrochloride] results in decreased expression of ABCB1 protein
ABCB1 protein affects the activity of Raloxifene Hydrochloride
CTD PMID:16959878 PMID:17096884 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcb9 ATP binding cassette subfamily B member 9 affects expression ISO Raloxifene Hydrochloride affects the expression of ABCB9 mRNA CTD PMID:14699072 NCBI chr12:32,499,213...32,531,932
Ensembl chr12:32,499,225...32,531,931
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ABCC1 mRNA CTD PMID:19059307 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 affects expression ISO Raloxifene Hydrochloride affects the expression of ABCG1 mRNA CTD PMID:14699072 NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
JBrowse link
G Abhd2 abhydrolase domain containing 2, acylglycerol lipase decreases expression ISO Raloxifene Hydrochloride results in decreased expression of ABHD2 mRNA CTD PMID:26865669 NCBI chr 1:133,217,403...133,298,564
Ensembl chr 1:133,217,375...133,299,061
JBrowse link
G Abhd5 abhydrolase domain containing 5, lysophosphatidic acid acyltransferase affects expression ISO Raloxifene Hydrochloride affects the expression of ABHD5 mRNA CTD PMID:14699072 NCBI chr 8:122,000,241...122,026,447
Ensembl chr 8:122,000,389...122,026,447
JBrowse link
G Abhd8 abhydrolase domain containing 8 affects response to substance ISO ABHD8 affects the susceptibility to Raloxifene Hydrochloride CTD PMID:32934756 NCBI chr16:18,144,464...18,151,201
Ensembl chr16:18,144,464...18,157,667
JBrowse link
G Ablim3 actin binding LIM protein family, member 3 affects expression ISO Raloxifene Hydrochloride affects the expression of ABLIM3 mRNA CTD PMID:14699072 NCBI chr18:55,256,135...55,376,629
Ensembl chr18:55,257,583...55,376,380
JBrowse link
G Acan aggrecan multiple interactions EXP Raloxifene Hydrochloride inhibits the reaction [Decitabine results in decreased expression of ACAN mRNA] CTD PMID:23385821 NCBI chr 1:132,981,582...133,044,416
Ensembl chr 1:132,981,582...133,043,627
JBrowse link
G Ace angiotensin I converting enzyme decreases expression ISO Raloxifene Hydrochloride results in decreased expression of ACE mRNA CTD PMID:15849065 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Ache acetylcholinesterase decreases activity ISO Raloxifene Hydrochloride results in decreased activity of ACHE protein CTD PMID:33844597 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Ackr3 atypical chemokine receptor 3 affects expression
multiple interactions
ISO Raloxifene Hydrochloride affects the expression of ACKR3 mRNA
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ACKR3 mRNA
CTD PMID:14699072 PMID:19059307 NCBI chr 9:90,799,682...90,811,246
Ensembl chr 9:90,799,686...90,811,237
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ACSL1 mRNA CTD PMID:19059307 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO Raloxifene Hydrochloride affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of ACTA2 protein] CTD PMID:32828944 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Acvrl1 activin A receptor like type 1 increases expression ISO Raloxifene Hydrochloride results in increased expression of ACVRL1 mRNA; Raloxifene Hydrochloride results in increased expression of ACVRL1 protein CTD PMID:20135064 NCBI chr 7:132,239,200...132,256,592
Ensembl chr 7:132,239,729...132,256,591
JBrowse link
G Adam19 ADAM metallopeptidase domain 19 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ADAM19 mRNA CTD PMID:19059307 NCBI chr10:30,491,362...30,583,115
Ensembl chr10:30,491,405...30,583,105
JBrowse link
G Adam22 ADAM metallopeptidase domain 22 decreases expression ISO Raloxifene Hydrochloride results in decreased expression of ADAM22 mRNA CTD PMID:19429434 NCBI chr 4:25,716,055...25,970,932
Ensembl chr 4:25,715,990...25,964,962
JBrowse link
G Adamtsl3 ADAMTS-like 3 affects expression ISO Raloxifene Hydrochloride affects the expression of ADAMTSL3 mRNA CTD PMID:14699072 NCBI chr 1:136,288,793...136,596,986
Ensembl chr 1:136,288,793...136,596,986
JBrowse link
G Adcy2 adenylate cyclase 2 affects expression EXP Raloxifene Hydrochloride affects the expression of ADCY2 mRNA CTD PMID:16079270 NCBI chr 1:34,375,639...34,822,252
Ensembl chr 1:34,375,895...34,822,236
JBrowse link
G Adcyap1 adenylate cyclase activating polypeptide 1 affects expression EXP Raloxifene Hydrochloride affects the expression of ADCYAP1 mRNA CTD PMID:16079270 NCBI chr 9:113,102,632...113,122,500
Ensembl chr 9:113,103,718...113,109,773
JBrowse link
G Adgra3 adhesion G protein-coupled receptor A3 increases expression ISO Raloxifene Hydrochloride results in increased expression of ADGRA3 mRNA CTD PMID:19429434 NCBI chr14:60,874,719...60,976,341
Ensembl chr14:60,874,715...60,976,332
JBrowse link
G Adgrb2 adhesion G protein-coupled receptor B2 affects expression ISO Raloxifene Hydrochloride affects the expression of ADGRB2 mRNA CTD PMID:14699072 NCBI chr 5:142,299,190...142,362,540
Ensembl chr 5:142,331,329...142,362,540
JBrowse link
G Adgrg1 adhesion G protein-coupled receptor G1 affects expression ISO Raloxifene Hydrochloride affects the expression of ADGRG1 mRNA CTD PMID:14699072 NCBI chr19:10,003,963...10,041,122
Ensembl chr19:10,003,975...10,041,108
JBrowse link
G Adh1c alcohol dehydrogenase 1C (class I), gamma polypeptide increases expression EXP Raloxifene Hydrochloride results in increased expression of ADH1 mRNA CTD PMID:15576828 NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing increases expression ISO Raloxifene Hydrochloride results in increased expression of ADIPOQ mRNA CTD PMID:16643890 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Adora2a adenosine A2a receptor increases expression ISO Raloxifene Hydrochloride results in increased expression of ADORA2A mRNA CTD PMID:15849065 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386
JBrowse link
G Adora2b adenosine A2B receptor multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ADORA2B mRNA CTD PMID:19059307 NCBI chr10:46,940,394...46,956,772
Ensembl chr10:46,940,384...46,956,772
JBrowse link
G Adra1a adrenoceptor alpha 1A decreases expression EXP Raloxifene Hydrochloride results in decreased expression of ADRA1A mRNA CTD PMID:20201831 NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500
JBrowse link
G Aebp1 AE binding protein 1 increases expression EXP Raloxifene Hydrochloride results in increased expression of AEBP1 mRNA CTD PMID:15576828 NCBI chr14:80,738,800...80,748,878
Ensembl chr14:80,738,892...80,748,877
JBrowse link
G Ago2 argonaute RISC catalytic component 2 affects expression
multiple interactions
ISO Raloxifene Hydrochloride affects the expression of AGO2 mRNA
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of AGO2 mRNA
CTD PMID:14699072 PMID:19059307 NCBI chr 7:105,018,202...105,105,118
Ensembl chr 7:105,029,120...105,104,974
JBrowse link
G Agt angiotensinogen multiple interactions ISO [Raloxifene Hydrochloride co-treated with Estradiol] inhibits the reaction [AGT protein results in increased phosphorylation of STAT3 protein]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [[Raloxifene Hydrochloride co-treated with Estradiol] inhibits the reaction [AGT protein results in increased phosphorylation of STAT3 protein]] CTD PMID:17336289 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Ahcyl1 adenosylhomocysteinase-like 1 affects expression ISO Raloxifene Hydrochloride affects the expression of AHCYL1 mRNA CTD PMID:14699072 NCBI chr 2:195,294,149...195,328,586
Ensembl chr 2:195,294,153...195,345,815
JBrowse link
G Ahnak AHNAK nucleoprotein decreases expression ISO Raloxifene Hydrochloride results in decreased expression of AHNAK mRNA CTD PMID:16514628 NCBI chr 1:205,882,225...205,970,934
Ensembl chr 1:205,882,273...205,970,926
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
affects binding
affects localization
ISO [Raloxifene Hydrochloride results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA
Raloxifene Hydrochloride binds to AHR protein
Raloxifene Hydrochloride inhibits the reaction [Methylcholanthrene binds to AHR protein]
Raloxifene Hydrochloride affects the localization of AHR protein
CTD PMID:19901195 PMID:24481452 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Aimp1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 increases expression ISO Raloxifene Hydrochloride results in increased expression of AIMP1 mRNA CTD PMID:12154049 NCBI chr 2:221,151,907...221,175,458
Ensembl chr 2:221,151,904...221,175,728
JBrowse link
G Ak3 adenylate kinase 3 affects expression EXP Raloxifene Hydrochloride affects the expression of AK3 mRNA CTD PMID:16079270 NCBI chr 1:226,737,472...226,764,647
Ensembl chr 1:226,739,318...226,764,625
JBrowse link
G Akap1 A-kinase anchoring protein 1 multiple interactions
affects expression
ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of AKAP1 mRNA
Raloxifene Hydrochloride affects the expression of AKAP1 mRNA
CTD PMID:14699072 PMID:19059307 NCBI chr10:73,621,021...73,654,123
Ensembl chr10:73,621,883...73,653,896
JBrowse link
G Akr7a2 aldo-keto reductase family 7, member A2 affects expression EXP Raloxifene Hydrochloride affects the expression of AKR7A2 mRNA CTD PMID:16079270 NCBI chr 5:151,552,375...151,560,914
Ensembl chr 5:151,552,343...151,560,909
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation
increases phosphorylation
multiple interactions
ISO
EXP
Raloxifene Hydrochloride results in decreased phosphorylation of AKT1 protein
Raloxifene Hydrochloride results in increased phosphorylation of AKT1 protein
Raloxifene Hydrochloride inhibits the reaction [TGFA protein results in increased phosphorylation of AKT1 protein]
CTD PMID:15590986 PMID:15876410 PMID:16798746 PMID:25537862 PMID:35007301 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Alad aminolevulinate dehydratase increases expression ISO Raloxifene Hydrochloride results in increased expression of ALAD mRNA CTD PMID:26865669 NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474
JBrowse link
G Alas2 5'-aminolevulinate synthase 2 affects expression EXP Raloxifene Hydrochloride affects the expression of ALAS2 mRNA CTD PMID:16079270 NCBI chr  X:19,463,146...19,486,526
Ensembl chr  X:19,463,171...19,486,519
JBrowse link
G Alcam activated leukocyte cell adhesion molecule multiple interactions ISO Raloxifene Hydrochloride inhibits the reaction [Estradiol results in decreased expression of ALCAM mRNA] CTD PMID:21185374 NCBI chr11:48,336,123...48,536,296
Ensembl chr11:48,336,169...48,537,954
JBrowse link
G Alox5 arachidonate 5-lipoxygenase multiple interactions ISO [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of ALOX5 mRNA CTD PMID:24431404 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions EXP Raloxifene Hydrochloride inhibits the reaction [Decitabine results in increased expression of ALPL mRNA] CTD PMID:23385821 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
JBrowse link
G Amigo2 adhesion molecule with Ig like domain 2 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of AMIGO2 mRNA CTD PMID:19059307 NCBI chr 7:128,391,493...128,394,589
Ensembl chr 7:128,390,412...128,394,695
JBrowse link
G Amotl2 angiomotin like 2 affects expression ISO Raloxifene Hydrochloride affects the expression of AMOTL2 mRNA CTD PMID:14699072 NCBI chr 8:103,303,368...103,319,161
Ensembl chr 8:103,302,992...103,318,910
JBrowse link
G Ang angiogenin increases expression ISO Raloxifene Hydrochloride results in increased expression of ANG mRNA CTD PMID:19429434 NCBI chr15:24,312,711...24,323,361 JBrowse link
G Angptl2 angiopoietin-like 2 affects expression ISO Raloxifene Hydrochloride affects the expression of ANGPTL2 mRNA CTD PMID:14699072 NCBI chr 3:16,517,185...16,547,024
Ensembl chr 3:16,517,420...16,548,178
JBrowse link
G Angptl7 angiopoietin like 7 decreases expression ISO Raloxifene Hydrochloride results in decreased expression of ANGPTL7 mRNA CTD PMID:16202921 NCBI chr 5:158,932,096...158,937,281
Ensembl chr 5:158,932,794...158,937,324
JBrowse link
G Ank3 ankyrin 3 affects expression EXP Raloxifene Hydrochloride affects the expression of ANK3 mRNA CTD PMID:16079270 NCBI chr20:18,602,267...19,225,831
Ensembl chr20:18,602,786...19,086,300
JBrowse link
G Ankrd1 ankyrin repeat domain 1 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ANKRD1 mRNA CTD PMID:19059307 NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919
JBrowse link
G Ankrd28 ankyrin repeat domain 28 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of ANKRD28 mRNA CTD PMID:19059307 NCBI chr16:6,918,487...7,050,244
Ensembl chr16:6,914,336...7,050,249
JBrowse link
G Aopep aminopeptidase O multiple interactions ISO [Raloxifene Hydrochloride co-treated with Estradiol] results in increased expression of AOPEP mRNA CTD PMID:21185374 NCBI chr17:1,811,281...2,127,316
Ensembl chr17:1,811,980...2,127,331
JBrowse link
G Aox1 aldehyde oxidase 1 multiple interactions
decreases activity
ISO Raloxifene Hydrochloride inhibits the reaction [AOX1 protein results in increased metabolism of zoniporide]
Raloxifene Hydrochloride results in decreased activity of AOX1 protein
CTD PMID:20040581 NCBI chr 9:59,579,621...59,658,772
Ensembl chr 9:59,579,649...59,658,770
JBrowse link
G Ap1g1 adaptor related protein complex 1 subunit gamma 1 affects expression ISO Raloxifene Hydrochloride affects the expression of AP1G1 mRNA CTD PMID:14699072 NCBI chr19:37,744,633...37,831,134
Ensembl chr19:37,744,633...37,829,167
JBrowse link
G Apc APC regulator of WNT signaling pathway multiple interactions
affects response to substance
ISO [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of ALOX5 mRNA; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of CCL6 mRNA; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of CCND1 mRNA; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of CD24 mRNA; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of CD24 protein; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of CD44 mRNA; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of CD44 protein; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of CTNNB1 mRNA; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of EPCAM mRNA; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of EPCAM protein; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of ESR2 protein; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of LAMB1 mRNA; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of LGR5 mRNA; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of LGR5 protein; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of PCNA protein; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of PTGES mRNA; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of PTGS2 mRNA; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of PTGS2 protein CTD PMID:24431404 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 multiple interactions
increases expression
EXP [Raloxifene Hydrochloride co-treated with Kainic Acid] results in increased expression of APEX1 mRNA
Raloxifene Hydrochloride results in increased expression of APEX1 mRNA
CTD PMID:16120186 NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785
JBrowse link
G Apod apolipoprotein D increases expression
multiple interactions
ISO Raloxifene Hydrochloride results in increased expression of APOD mRNA
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in decreased expression of APOD protein]
CTD PMID:16514628 PMID:27163517 NCBI chr11:69,431,261...69,452,306
Ensembl chr11:69,431,260...69,452,305
JBrowse link
G Apoe apolipoprotein E multiple interactions ISO Raloxifene Hydrochloride affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of ACTA2 protein]; Raloxifene Hydrochloride affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of CD68 protein]; Raloxifene Hydrochloride affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of ICAM1 protein]; Raloxifene Hydrochloride affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of IL6 protein]; Raloxifene Hydrochloride affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of VCAM1 protein]; Raloxifene Hydrochloride affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the phosphorylation of STAT3 protein]; Raloxifene Hydrochloride affects the reaction [[APOE protein affects the susceptibility to IL6 protein] which affects the phosphorylation of STAT3 protein] CTD PMID:32828944 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G App amyloid beta precursor protein multiple interactions
affects binding
ISO Raloxifene Hydrochloride inhibits the reaction [APP protein results in increased expression of TGFB1 mRNA]; Raloxifene Hydrochloride inhibits the reaction [APP protein results in increased expression of TNF mRNA]
Raloxifene Hydrochloride binds to APP protein
CTD PMID:31583774 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Ar androgen receptor decreases expression
affects expression
multiple interactions
ISO
EXP
Raloxifene Hydrochloride results in decreased expression of AR mRNA; Raloxifene Hydrochloride results in decreased expression of AR protein
Raloxifene Hydrochloride affects the expression of AR mRNA
[Raloxifene Hydrochloride co-treated with Estradiol] results in decreased expression of AR protein
CTD PMID:11867264 PMID:15731164 PMID:16837883 PMID:27163517 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Areg amphiregulin multiple interactions
decreases expression
increases expression
ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of AREG mRNA
Raloxifene Hydrochloride results in decreased expression of AREG mRNA
Raloxifene Hydrochloride inhibits the reaction [Estrogens, Conjugated (USP) results in increased expression of AREG mRNA]
Raloxifene Hydrochloride results in increased expression of AREG mRNA
CTD PMID:16514628 PMID:19022889 PMID:19059307 PMID:26865669 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
JBrowse link
G Arg2 arginase 2 increases expression ISO Raloxifene Hydrochloride results in increased expression of ARG2 mRNA CTD PMID:22841776 NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378
JBrowse link
G Arhgap29 Rho GTPase activating protein 29 affects expression ISO Raloxifene Hydrochloride affects the expression of ARHGAP29 mRNA CTD PMID:14699072 NCBI chr 2:210,060,036...210,132,572
Ensembl chr 2:210,071,199...210,132,028
JBrowse link
G Arid5a AT-rich interaction domain 5A multiple interactions ISO ARID5A protein inhibits the reaction [Raloxifene Hydrochloride results in increased activity of ESR1 protein] CTD PMID:15941852 NCBI chr 9:38,534,612...38,549,467
Ensembl chr 9:38,534,590...38,547,597
JBrowse link
G Arid5b AT-rich interaction domain 5B affects expression ISO Raloxifene Hydrochloride affects the expression of ARID5B mRNA CTD PMID:14699072 NCBI chr20:20,307,731...20,490,746
Ensembl chr20:20,307,731...20,487,433
JBrowse link
G Arl1 ARF like GTPase 1 affects expression EXP Raloxifene Hydrochloride affects the expression of ARL1 mRNA CTD PMID:16079270 NCBI chr 7:23,120,004...23,131,173
Ensembl chr 7:23,119,589...23,131,898
JBrowse link
G Arl4c ARF like GTPase 4C multiple interactions
affects expression
ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ARL4C mRNA
Raloxifene Hydrochloride affects the expression of ARL4C mRNA
CTD PMID:14699072 PMID:19059307 NCBI chr 9:89,300,335...89,303,770
Ensembl chr 9:89,298,005...89,304,513
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions ISO ARNT protein affects the reaction [Raloxifene Hydrochloride results in increased expression of CYP1A1 protein]; ARNT protein affects the reaction [Raloxifene Hydrochloride results in increased expression of NQO1 protein] CTD PMID:24481452 NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580
JBrowse link
G Arnt2 aryl hydrocarbon receptor nuclear translocator 2 increases expression ISO Raloxifene Hydrochloride results in increased expression of ARNT2 mRNA CTD PMID:16514628 NCBI chr 1:138,236,235...138,392,868
Ensembl chr 1:138,189,940...138,393,153
JBrowse link
G Asb13 ankyrin repeat and SOCS box-containing 13 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ASB13 mRNA CTD PMID:19059307 NCBI chr17:66,564,653...66,583,365
Ensembl chr17:66,562,434...66,583,337
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) decreases expression ISO Raloxifene Hydrochloride results in decreased expression of ASNS mRNA CTD PMID:16514628 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
JBrowse link
G Atf3 activating transcription factor 3 multiple interactions
increases expression
ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ATF3 mRNA
Raloxifene Hydrochloride results in increased expression of ATF3 mRNA
CTD PMID:16497877 PMID:19059307 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Atf7ip activating transcription factor 7 interacting protein increases expression ISO Raloxifene Hydrochloride results in increased expression of ATF7IP mRNA CTD PMID:19429434 NCBI chr 4:169,385,872...169,471,652
Ensembl chr 4:169,385,872...169,471,650
JBrowse link
G Atg12 autophagy related 12 multiple interactions ISO Raloxifene Hydrochloride promotes the reaction [ATG12 protein binds to ATG5 protein] CTD PMID:25537862 NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418
JBrowse link
G Atg5 autophagy related 5 multiple interactions ISO Raloxifene Hydrochloride promotes the reaction [ATG12 protein binds to ATG5 protein] CTD PMID:25537862 NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 affects expression EXP Raloxifene Hydrochloride affects the expression of ATP1A1 mRNA CTD PMID:16079270 NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837
JBrowse link
G Atp9a ATPase phospholipid transporting 9A (putative) affects expression ISO Raloxifene Hydrochloride affects the expression of ATP9A mRNA CTD PMID:14699072 NCBI chr 3:157,360,354...157,467,628
Ensembl chr 3:157,360,359...157,467,818
JBrowse link
G Atxn3 ataxin 3 increases expression ISO Raloxifene Hydrochloride results in increased expression of ATXN3 mRNA CTD PMID:33269387 NCBI chr 6:121,072,228...121,107,902
Ensembl chr 6:121,074,448...121,107,902
JBrowse link
G Aurka aurora kinase A decreases expression ISO Raloxifene Hydrochloride results in decreased expression of AURKA mRNA CTD PMID:16514628 NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390
JBrowse link
G Avp arginine vasopressin decreases expression
multiple interactions
ISO Raloxifene Hydrochloride results in decreased expression of AVP mRNA
4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [Raloxifene Hydrochloride results in decreased expression of AVP mRNA]; GPER1 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of AVP mRNA]; sotrastaurin inhibits the reaction [Raloxifene Hydrochloride results in decreased expression of AVP mRNA]; U 0126 inhibits the reaction [Raloxifene Hydrochloride results in decreased expression of AVP mRNA]
CTD PMID:26200092 NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425
JBrowse link
G Axin2 axin 2 decreases expression
multiple interactions
ISO Raloxifene Hydrochloride results in decreased expression of AXIN2 mRNA
[Raloxifene Hydrochloride co-treated with PX-866] results in decreased expression of AXIN2 mRNA
CTD PMID:27017931 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231
JBrowse link
G Bad BCL2-associated agonist of cell death increases cleavage ISO Raloxifene Hydrochloride results in increased cleavage of BAD protein CTD PMID:12084714 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bak1 BCL2-antagonist/killer 1 decreases expression ISO Raloxifene Hydrochloride results in decreased expression of BAK1 mRNA CTD PMID:16202921 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bap1 BRCA1 associated deubiquitinase 1 multiple interactions ISO [SOD1 protein mutant form affects the susceptibility to Raloxifene Hydrochloride] which results in decreased expression of BAP1 mRNA CTD PMID:33269387 NCBI chr16:6,446,709...6,455,535
Ensembl chr16:6,446,709...6,455,535
JBrowse link
G Bax BCL2 associated X, apoptosis regulator affects expression
increases expression
multiple interactions
ISO Raloxifene Hydrochloride affects the expression of BAX protein
Raloxifene Hydrochloride results in increased expression of BAX mRNA
[Raloxifene Hydrochloride co-treated with Resveratrol] results in increased expression of BAX mRNA
CTD PMID:16009171 PMID:29705353 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcas1 brain enriched myelin associated protein 1 multiple interactions ISO [Raloxifene Hydrochloride co-treated with Estradiol] results in increased expression of BCAS1 mRNA CTD PMID:21185374 NCBI chr 3:159,136,077...159,219,072
Ensembl chr 3:159,136,083...159,219,106
JBrowse link
G Bcl2 BCL2, apoptosis regulator affects expression
decreases expression
increases expression
multiple interactions
ISO Raloxifene Hydrochloride affects the expression of BCL2 protein
Raloxifene Hydrochloride results in decreased expression of BCL2 mRNA; Raloxifene Hydrochloride results in decreased expression of BCL2 protein
Raloxifene Hydrochloride results in increased expression of BCL2 protein
[Resveratrol co-treated with Raloxifene Hydrochloride] results in decreased expression of BCL2 mRNA
CTD PMID:16009171 PMID:16566921 PMID:16973256 PMID:17220163 PMID:20945400 More... NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO Raloxifene Hydrochloride results in decreased expression of BCL2L1 protein CTD PMID:28430601 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479
JBrowse link
G Bcl2l11 Bcl2-like 11 increases expression ISO Raloxifene Hydrochloride results in increased expression of BCL2L11 mRNA CTD PMID:19429434 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
JBrowse link
G Bcl3 BCL3, transcription coactivator multiple interactions ISO Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased expression of BCL3 mRNA] CTD PMID:12072388 NCBI chr 1:79,471,368...79,485,908
Ensembl chr 1:79,471,369...79,485,607
JBrowse link
G Bcl6 BCL6, transcription repressor increases expression ISO Raloxifene Hydrochloride results in increased expression of BCL6 mRNA CTD PMID:16497877 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389
JBrowse link
G Becn1 beclin 1 increases expression ISO Raloxifene Hydrochloride results in increased expression of BECN1 protein CTD PMID:25537862 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Bglap bone gamma-carboxyglutamate protein decreases expression ISO Raloxifene Hydrochloride results in decreased expression of BGLAP protein CTD PMID:17823083 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
JBrowse link
G Bgn biglycan increases expression ISO
EXP
Raloxifene Hydrochloride results in increased expression of BGN mRNA CTD PMID:15576828 PMID:19429434 NCBI chr  X:151,197,296...151,209,458
Ensembl chr  X:151,197,273...151,209,461
JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 multiple interactions ISO [Raloxifene Hydrochloride co-treated with PX-866] results in increased expression of BHLHE40 mRNA CTD PMID:27017931 NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of BIRC3 mRNA CTD PMID:19059307 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO Raloxifene Hydrochloride results in decreased expression of BIRC5 protein CTD PMID:28430601 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Blzf1 basic leucine zipper nuclear factor 1 decreases expression ISO Raloxifene Hydrochloride results in decreased expression of BLZF1 mRNA CTD PMID:19429434 NCBI chr13:76,641,757...76,656,977
Ensembl chr13:76,641,515...76,656,999
JBrowse link
G Bmp7 bone morphogenetic protein 7 affects expression ISO Raloxifene Hydrochloride affects the expression of BMP7 mRNA CTD PMID:14699072 NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788
JBrowse link
G Brinp2 BMP/retinoic acid inducible neural specific 2 multiple interactions ISO Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of BRINP2 mRNA] CTD PMID:21185374 NCBI chr13:70,431,006...70,532,766
Ensembl chr13:70,431,010...70,531,810
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO Raloxifene Hydrochloride results in increased expression of BTG2 mRNA CTD PMID:22965848 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
JBrowse link
G C1qb complement C1q B chain affects expression EXP Raloxifene Hydrochloride affects the expression of C1QB mRNA CTD PMID:16079270 NCBI chr 5:149,118,843...149,124,394
Ensembl chr 5:149,118,846...149,124,407
JBrowse link
G C2cd2 C2 calcium-dependent domain containing 2 multiple interactions
affects expression
ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of C2CD2 mRNA
Raloxifene Hydrochloride affects the expression of C2CD2 mRNA
CTD PMID:14699072 PMID:19059307 NCBI chr11:37,225,321...37,289,741
Ensembl chr11:37,227,415...37,289,739
JBrowse link
G C3 complement C3 increases expression ISO Raloxifene Hydrochloride results in increased expression of C3 mRNA CTD PMID:12370124 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
JBrowse link
G C6h14orf132 similar to human chromosome 14 open reading frame 132 affects expression
multiple interactions
ISO Raloxifene Hydrochloride affects the expression of C14ORF132 mRNA
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of C14ORF132 mRNA
CTD PMID:14699072 PMID:19059307 NCBI chr 6:124,365,466...124,398,449 JBrowse link
G Cabin1 calcineurin binding protein 1 increases expression EXP Raloxifene Hydrochloride results in increased expression of CABIN1 mRNA CTD PMID:15576828 NCBI chr20:12,893,314...13,015,357
Ensembl chr20:12,893,358...13,015,357
JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H decreases expression ISO Raloxifene Hydrochloride results in decreased expression of CACNA1H mRNA CTD PMID:21228613 NCBI chr10:14,390,104...14,448,204
Ensembl chr10:14,390,113...14,448,376
JBrowse link
G Cacna1i calcium voltage-gated channel subunit alpha1 I decreases expression ISO Raloxifene Hydrochloride results in decreased expression of CACNA1I mRNA CTD PMID:21228613 NCBI chr 7:111,835,996...111,947,418
Ensembl chr 7:111,836,012...111,944,688
JBrowse link
G Calb2 calbindin 2 increases expression ISO Raloxifene Hydrochloride results in increased expression of CALB2 mRNA CTD PMID:17962382 NCBI chr19:38,114,435...38,141,438
Ensembl chr19:38,114,424...38,141,438
JBrowse link
G Cald1 caldesmon 1 decreases expression ISO Raloxifene Hydrochloride results in decreased expression of CALD1 mRNA CTD PMID:19429434 NCBI chr 4:63,265,781...63,446,938
Ensembl chr 4:63,265,942...63,446,932
JBrowse link
G Calm1 calmodulin 1 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CALM1 mRNA CTD PMID:19059307 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
JBrowse link
G Cap2 cyclase associated actin cytoskeleton regulatory protein 2 decreases expression EXP Raloxifene Hydrochloride results in decreased expression of CAP2 mRNA CTD PMID:15576828 NCBI chr17:18,054,234...18,203,453
Ensembl chr17:18,054,431...18,203,373
JBrowse link
G Capn2 calpain 2 affects expression ISO Raloxifene Hydrochloride affects the expression of CAPN2 mRNA CTD PMID:14699072 NCBI chr13:94,150,244...94,200,969
Ensembl chr13:94,150,240...94,200,969
JBrowse link
G Car12 carbonic anhydrase 12 affects expression
multiple interactions
decreases expression
ISO Raloxifene Hydrochloride affects the expression of CA12 mRNA
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of CA12 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CA12 mRNA
Raloxifene Hydrochloride results in decreased expression of CA12 mRNA
CTD PMID:14699072 PMID:19059307 PMID:26865669 NCBI chr 8:67,274,739...67,330,428
Ensembl chr 8:67,274,359...67,330,440
JBrowse link
G Car4 carbonic anhydrase 4 affects expression EXP Raloxifene Hydrochloride affects the expression of CA4 mRNA CTD PMID:16079270 NCBI chr10:69,827,945...69,836,501
Ensembl chr10:69,827,945...69,836,501
JBrowse link
G Card10 caspase recruitment domain family, member 10 affects expression ISO Raloxifene Hydrochloride affects the expression of CARD10 mRNA CTD PMID:14699072 NCBI chr 7:110,330,460...110,371,551
Ensembl chr 7:110,330,408...110,359,224
JBrowse link
G Caskin2 cask-interacting protein 2 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CASKIN2 mRNA CTD PMID:19059307 NCBI chr10:101,027,196...101,041,429
Ensembl chr10:101,027,260...101,041,414
JBrowse link
G Casp3 caspase 3 increases expression
multiple interactions
decreases expression
increases cleavage
ISO
EXP
Raloxifene Hydrochloride results in increased expression of CASP3 mRNA; Raloxifene Hydrochloride results in increased expression of CASP3 protein modified form
Raloxifene Hydrochloride inhibits the reaction [Decitabine results in increased activity of CASP3 protein]
Raloxifene Hydrochloride results in decreased expression of CASP3 mRNA; Raloxifene Hydrochloride results in decreased expression of CASP3 protein
Raloxifene Hydrochloride results in increased cleavage of CASP3 protein
[Resveratrol co-treated with Raloxifene Hydrochloride] results in decreased expression of CASP3 mRNA; STAT3 protein affects the reaction [Raloxifene Hydrochloride results in increased cleavage of CASP3 protein]
CTD PMID:20945400 PMID:22965848 PMID:23385821 PMID:27999800 PMID:28430601 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp4 caspase 4 increases expression ISO Raloxifene Hydrochloride results in increased expression of CASP4 mRNA CTD PMID:12154049 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
JBrowse link
G Casp7 caspase 7 multiple interactions
affects expression
ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CASP7 mRNA
Raloxifene Hydrochloride affects the expression of CASP7 mRNA
CTD PMID:14699072 PMID:19059307 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp8 caspase 8 multiple interactions
decreases expression
increases expression
ISO [Resveratrol co-treated with Raloxifene Hydrochloride] results in decreased expression of CASP8 mRNA
Raloxifene Hydrochloride results in decreased expression of CASP8 mRNA; Raloxifene Hydrochloride results in decreased expression of CASP8 protein
Raloxifene Hydrochloride results in increased expression of CASP8 mRNA
CTD PMID:27999800 PMID:29705353 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Cat catalase increases activity ISO Raloxifene Hydrochloride results in increased activity of CAT protein CTD PMID:17227729 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cav1 caveolin 1 affects expression
multiple interactions
increases expression
ISO
EXP
Raloxifene Hydrochloride affects the expression of CAV1 mRNA
fulvestrant inhibits the reaction [Raloxifene Hydrochloride results in increased expression of CAV1 mRNA]; fulvestrant inhibits the reaction [Raloxifene Hydrochloride results in increased expression of CAV1 protein]
Raloxifene Hydrochloride results in increased expression of CAV1 mRNA; Raloxifene Hydrochloride results in increased expression of CAV1 protein
CTD PMID:14699072 PMID:17091190 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Cbx1 chromobox 1 decreases expression ISO Raloxifene Hydrochloride results in decreased expression of CBX1 mRNA CTD PMID:16514628 NCBI chr10:81,770,307...81,789,981
Ensembl chr10:81,770,342...81,791,096
JBrowse link
G Cbx3 chromobox 3 decreases expression ISO Raloxifene Hydrochloride results in decreased expression of CBX3 mRNA CTD PMID:19429434 NCBI chr 4:80,545,450...80,559,284
Ensembl chr 4:80,546,010...80,559,283
Ensembl chr 4:80,546,010...80,559,283
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
affects expression
decreases activity
ISO
EXP
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CCL2 mRNA; fulvestrant inhibits the reaction [Raloxifene Hydrochloride results in decreased activity of CCL2 protein]
Raloxifene Hydrochloride affects the expression of CCL2 mRNA
Raloxifene Hydrochloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of CCL2 mRNA]
CTD PMID:14699072 PMID:17006379 PMID:19059307 PMID:25305410 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 affects expression
multiple interactions
ISO Raloxifene Hydrochloride affects the expression of CCL20 mRNA
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CCL20 mRNA
Fulvestrant inhibits the reaction [Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased expression of CCL20 protein]]; Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased expression of CCL20 protein]
CTD PMID:14699072 PMID:19059307 PMID:24722370 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions
decreases expression
ISO Raloxifene Hydrochloride inhibits the reaction [ESR1 protein binds to CCL3 promoter]; Raloxifene Hydrochloride inhibits the reaction [RELA protein binds to CCL3 promoter]
Raloxifene Hydrochloride results in decreased expression of CCL3 mRNA
CTD PMID:16497877 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression
decreases expression
ISO Raloxifene Hydrochloride results in increased expression of CCL5 mRNA
Raloxifene Hydrochloride results in decreased expression of CCL5 protein
CTD PMID:12154049 PMID:16842799 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccl9 C-C motif chemokine ligand 9 multiple interactions ISO [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of CCL6 mRNA CTD PMID:24431404 NCBI chr10:68,366,486...68,371,408
Ensembl chr10:68,366,487...68,371,369
JBrowse link
G Ccn3 cellular communication network factor 3 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of CCN3 mRNA CTD PMID:19059307 NCBI chr 7:86,094,000...86,101,022
Ensembl chr 7:86,094,000...86,101,019
JBrowse link
G Ccna2 cyclin A2 increases expression ISO Raloxifene Hydrochloride results in increased expression of CCNA2 mRNA; Raloxifene Hydrochloride results in increased expression of CCNA2 protein CTD PMID:17445807 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnb1 cyclin B1 increases expression ISO Raloxifene Hydrochloride results in increased expression of CCNB1 mRNA; Raloxifene Hydrochloride results in increased expression of CCNB1 protein CTD PMID:12154049 PMID:17445807 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnd1 cyclin D1 multiple interactions
affects expression
decreases expression
ISO
EXP
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CCND1 mRNA; [Raloxifene Hydrochloride co-treated with PX-866] results in decreased expression of CCND1 mRNA
Raloxifene Hydrochloride affects the expression of CCND1 mRNA
Raloxifene Hydrochloride results in decreased expression of CCND1 mRNA
[Raloxifene Hydrochloride co-treated with Bexarotene] affects the reaction [Azoxymethane affects the expression of CCND1 mRNA]; [Raloxifene Hydrochloride co-treated with Bexarotene] affects the reaction [Azoxymethane affects the expression of CCND1 protein]; Raloxifene Hydrochloride affects the reaction [Azoxymethane affects the expression of CCND1 mRNA]; Raloxifene Hydrochloride affects the reaction [Azoxymethane affects the expression of CCND1 protein]
[APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of CCND1 mRNA
CTD PMID:14699072 PMID:19059307 PMID:22965848 PMID:24080207 PMID:24431404 More... NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccne2 cyclin E2 multiple interactions
decreases expression
ISO [Raloxifene Hydrochloride co-treated with PX-866] results in decreased expression of CCNE2 mRNA
Raloxifene Hydrochloride results in decreased expression of CCNE2 protein
CTD PMID:26660119 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632
JBrowse link
G Ccng2 cyclin G2 increases expression ISO Raloxifene Hydrochloride results in increased expression of CCNG2 mRNA CTD PMID:16497877 PMID:26865669 NCBI chr14:14,804,321...14,812,819
Ensembl chr14:14,804,322...14,812,830
JBrowse link
G Cd200 Cd200 molecule decreases expression EXP Raloxifene Hydrochloride results in decreased expression of CD200 mRNA CTD PMID:15576828 NCBI chr11:55,410,166...55,437,527
Ensembl chr11:55,410,196...55,501,648
JBrowse link
G Cd24 CD24 molecule increases expression
multiple interactions
ISO Raloxifene Hydrochloride results in increased expression of CD24 mRNA
[APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of CD24 mRNA; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of CD24 protein
CTD PMID:16514628 PMID:24431404 NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662
JBrowse link
G Cd3g CD3 gamma subunit of T-cell receptor complex affects expression EXP Raloxifene Hydrochloride affects the expression of CD3G mRNA CTD PMID:16079270 NCBI chr 8:45,280,797...45,287,271
Ensembl chr 8:45,281,204...45,287,147
JBrowse link
G Cd40 CD40 molecule multiple interactions ISO Raloxifene Hydrochloride inhibits the reaction [Lipopolysaccharides results in increased expression of CD40 protein] CTD PMID:16081843 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
JBrowse link
G Cd44 CD44 molecule decreases expression
multiple interactions
ISO Raloxifene Hydrochloride results in decreased expression of CD44 mRNA
[APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of CD44 mRNA; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of CD44 protein
CTD PMID:24431404 PMID:26865669 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cd52 CD52 molecule affects expression EXP Raloxifene Hydrochloride affects the expression of CD52 mRNA CTD PMID:16079270 NCBI chr 5:146,319,789...146,321,348
Ensembl chr 5:146,319,969...146,321,348
JBrowse link
G Cd68 Cd68 molecule multiple interactions ISO Raloxifene Hydrochloride affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of CD68 protein] CTD PMID:32828944 NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697
JBrowse link
G Cd74 CD74 molecule affects expression EXP Raloxifene Hydrochloride affects the expression of CD74 mRNA CTD PMID:16079270 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003
JBrowse link
G Cd80 Cd80 molecule multiple interactions ISO Raloxifene Hydrochloride inhibits the reaction [Lipopolysaccharides results in increased expression of CD80 protein] CTD PMID:16081843 NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030
JBrowse link
G Cd86 CD86 molecule multiple interactions ISO Raloxifene Hydrochloride inhibits the reaction [Lipopolysaccharides results in increased expression of CD86 protein] CTD PMID:16081843 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G Cd8a CD8 subunit alpha affects expression EXP Raloxifene Hydrochloride affects the expression of CD8A mRNA CTD PMID:16079270 NCBI chr 4:103,365,804...103,370,041
Ensembl chr 4:103,365,804...103,370,040
JBrowse link
G Cdc6 cell division cycle 6 multiple interactions ISO [Raloxifene Hydrochloride co-treated with PX-866] results in decreased expression of CDC6 mRNA CTD PMID:26660119 NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011
JBrowse link
G Cdh2 cadherin 2 affects expression
multiple interactions
ISO
EXP
Raloxifene Hydrochloride affects the expression of CDH2 mRNA
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CDH2 mRNA
CTD PMID:14699072 PMID:16079270 PMID:19059307 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
JBrowse link
G Cdh6 cadherin 6 affects expression EXP Raloxifene Hydrochloride affects the expression of CDH6 mRNA CTD PMID:16079270 NCBI chr 2:62,079,139...62,225,298
Ensembl chr 2:62,079,137...62,225,228
JBrowse link
G Cdk1 cyclin-dependent kinase 1 multiple interactions ISO Raloxifene Hydrochloride promotes the reaction [Estradiol results in increased expression of CDK1 mRNA]; trichostatin A inhibits the reaction [Raloxifene Hydrochloride promotes the reaction [Estradiol results in increased expression of CDK1 mRNA]] CTD PMID:22476901 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions EXP [Raloxifene Hydrochloride co-treated with Bexarotene] affects the reaction [Azoxymethane affects the expression of CDK2 protein] CTD PMID:24080207 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CDK5R1 mRNA CTD PMID:19059307 NCBI chr10:65,484,266...65,485,467
Ensembl chr10:65,483,941...65,488,456
JBrowse link
G Cdk5rap3 CDK5 regulatory subunit associated protein 3 affects expression EXP Raloxifene Hydrochloride affects the expression of CDK5RAP3 mRNA CTD PMID:16079270 NCBI chr10:81,894,393...81,903,581
Ensembl chr10:81,894,393...81,903,590
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions
ISO
EXP
Raloxifene Hydrochloride results in increased expression of CDKN1A mRNA; Raloxifene Hydrochloride results in increased expression of CDKN1A protein
[Raloxifene Hydrochloride co-treated with Bexarotene] affects the reaction [Azoxymethane affects the expression of CDKN1A protein]
[Raloxifene Hydrochloride co-treated with PX-866] results in increased expression of CDKN1A mRNA
CTD PMID:12154049 PMID:16497877 PMID:24080207 PMID:27017931 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression ISO Raloxifene Hydrochloride results in increased expression of CDKN1B protein CTD PMID:16536755 PMID:22965848 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cdo1 cysteine dioxygenase type 1 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CDO1 mRNA CTD PMID:19059307 NCBI chr18:39,432,473...39,447,253
Ensembl chr18:39,432,474...39,447,296
JBrowse link
G Cdon cell adhesion associated, oncogene regulated affects expression ISO Raloxifene Hydrochloride affects the expression of CDON mRNA CTD PMID:14699072 NCBI chr 8:33,775,123...33,861,635
Ensembl chr 8:33,806,183...33,859,033
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha decreases expression
multiple interactions
ISO Raloxifene Hydrochloride results in decreased expression of CEBPA mRNA
IWR-1 compound inhibits the reaction [Raloxifene Hydrochloride inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CEBPA protein]]; Raloxifene Hydrochloride inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CEBPA protein]
CTD PMID:15849065 PMID:31470850 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta affects expression
multiple interactions
increases expression
ISO Raloxifene Hydrochloride affects the expression of CEBPB mRNA
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CEBPB mRNA
Raloxifene Hydrochloride results in increased expression of CEBPB mRNA
CTD PMID:14699072 PMID:16497877 PMID:19059307 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
JBrowse link
G Cenpa centromere protein A decreases expression ISO Raloxifene Hydrochloride results in decreased expression of CENPA mRNA CTD PMID:16514628 NCBI chr 6:25,700,142...25,711,767
Ensembl chr 6:25,700,142...25,711,675
JBrowse link
G Cers6 ceramide synthase 6 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CERS6 mRNA CTD PMID:19059307 NCBI chr 3:53,630,637...53,879,692
Ensembl chr 3:53,630,959...53,876,848
JBrowse link
G Cfd complement factor D increases expression EXP Raloxifene Hydrochloride results in increased expression of CFD mRNA CTD PMID:15576828 NCBI chr 7:9,813,148...9,814,871
Ensembl chr 7:9,813,150...9,815,053
JBrowse link
G Chrd chordin affects expression ISO Raloxifene Hydrochloride affects the expression of CHRD mRNA CTD PMID:14699072 NCBI chr11:80,171,994...80,181,166
Ensembl chr11:80,171,994...80,180,673
JBrowse link
G Cish cytokine inducible SH2-containing protein multiple interactions ISO Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased expression of CISH mRNA] CTD PMID:12072388 NCBI chr 8:107,972,306...107,977,254
Ensembl chr 8:107,972,306...107,977,250
JBrowse link
G Ckb creatine kinase B increases activity
multiple interactions
ISO
EXP
Raloxifene Hydrochloride results in increased activity of CKB protein
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased activity of CKB protein]
CTD PMID:16621514 PMID:17029789 NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315
JBrowse link
G Clcn4 chloride voltage-gated channel 4 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CLCN4 mRNA CTD PMID:19059307 NCBI chr  X:23,729,194...23,795,391
Ensembl chr  X:23,729,338...23,793,238
JBrowse link
G Clcn6 chloride voltage-gated channel 6 increases expression ISO Raloxifene Hydrochloride results in increased expression of CLCN6 mRNA CTD PMID:16497877 NCBI chr 5:158,434,299...158,465,174
Ensembl chr 5:158,434,299...158,465,059
JBrowse link
G Clic4 chloride intracellular channel 4 increases expression ISO Raloxifene Hydrochloride results in increased expression of CLIC4 mRNA CTD PMID:16497877 NCBI chr 5:147,453,702...147,513,455
Ensembl chr 5:147,453,712...147,513,452
JBrowse link
G Clk1 CDC-like kinase 1 increases expression ISO Raloxifene Hydrochloride results in increased expression of CLK1 mRNA CTD PMID:12154049 NCBI chr 9:59,947,774...59,959,002
Ensembl chr 9:59,947,764...59,957,000
JBrowse link
G Clmn calmin increases expression ISO Raloxifene Hydrochloride results in increased expression of CLMN mRNA CTD PMID:26865669 NCBI chr 6:123,707,710...123,807,283
Ensembl chr 6:123,713,507...123,807,272
JBrowse link
G Clstn1 calsyntenin 1 decreases expression ISO Raloxifene Hydrochloride results in decreased expression of CLSTN1 mRNA CTD PMID:16514628 NCBI chr 5:160,031,235...160,094,585
Ensembl chr 5:160,031,308...160,094,583
JBrowse link
G Cltb clathrin, light chain B affects expression ISO Raloxifene Hydrochloride affects the expression of CLTB mRNA CTD PMID:14699072 NCBI chr17:10,001,512...10,019,201
Ensembl chr17:10,001,513...10,019,169
JBrowse link
G Clu clusterin increases expression ISO Raloxifene Hydrochloride results in increased expression of CLU mRNA CTD PMID:12370124 PMID:16202921 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Cnbp CCHC-type zinc finger, nucleic acid binding protein increases expression ISO Raloxifene Hydrochloride results in increased expression of CNBP mRNA CTD PMID:12154049 NCBI chr 4:120,302,768...120,311,694
Ensembl chr 4:120,302,771...120,311,637
JBrowse link
G Col10a1 collagen type X alpha 1 chain multiple interactions EXP Raloxifene Hydrochloride inhibits the reaction [Decitabine results in increased expression of COL10A1 mRNA] CTD PMID:23385821 NCBI chr20:38,183,103...38,189,488
Ensembl chr20:38,182,494...38,189,494
JBrowse link
G Col11a1 collagen type XI alpha 1 chain affects expression EXP Raloxifene Hydrochloride affects the expression of COL11A1 mRNA CTD PMID:16079270 NCBI chr 2:201,820,715...202,013,853
Ensembl chr 2:201,820,715...202,013,853
JBrowse link
G Col1a2 collagen type I alpha 2 chain decreases expression ISO Raloxifene Hydrochloride results in decreased expression of COL1A2 mRNA CTD PMID:19401787 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
JBrowse link
G Col26a1 collagen type XXVI alpha 1 chain increases expression ISO Raloxifene Hydrochloride results in increased expression of COL26A1 mRNA CTD PMID:17962382 NCBI chr12:19,792,693...19,938,556
Ensembl chr12:19,792,728...19,938,556
JBrowse link
G Col2a1 collagen type II alpha 1 chain multiple interactions EXP Raloxifene Hydrochloride promotes the reaction [Decitabine results in decreased expression of COL2A1 mRNA] CTD PMID:23385821 NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546
JBrowse link
G Col5a1 collagen type V alpha 1 chain affects expression EXP Raloxifene Hydrochloride affects the expression of COL5A1 mRNA CTD PMID:16079270 NCBI chr 3:11,208,429...11,356,715
Ensembl chr 3:11,208,512...11,354,588
JBrowse link
G Col5a2 collagen type V alpha 2 chain affects expression EXP Raloxifene Hydrochloride affects the expression of COL5A2 mRNA CTD PMID:16079270 NCBI chr 9:47,448,741...47,598,134
Ensembl chr 9:47,448,736...47,598,154
JBrowse link
G Copb2 COPI coat complex subunit beta 2 decreases expression ISO Raloxifene Hydrochloride results in decreased expression of COPB2 mRNA CTD PMID:16514628 NCBI chr 8:99,161,324...99,183,452
Ensembl chr 8:99,161,350...99,185,197
JBrowse link
G Cpb2 carboxypeptidase B2 decreases expression ISO Raloxifene Hydrochloride results in decreased expression of CPB2 protein CTD PMID:16167916 NCBI chr15:50,557,722...50,606,569
Ensembl chr15:50,557,717...50,606,556
JBrowse link
G Cpe carboxypeptidase E affects expression EXP Raloxifene Hydrochloride affects the expression of CPE mRNA CTD PMID:16079270 NCBI chr16:25,030,276...25,142,231
Ensembl chr16:25,030,276...25,142,233
JBrowse link
G Cpm carboxypeptidase M increases expression ISO Raloxifene Hydrochloride results in increased expression of CPM mRNA CTD PMID:19429434 NCBI chr 7:53,225,647...53,286,220
Ensembl chr 7:53,225,696...53,286,220
JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases phosphorylation EXP Raloxifene Hydrochloride results in increased phosphorylation of CREB1 protein CTD PMID:24782323 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Crebbp CREB binding protein multiple interactions ISO Raloxifene Hydrochloride promotes the reaction [CREBBP protein binds to IGF1 promoter]; Raloxifene Hydrochloride promotes the reaction [CREBBP protein binds to PTGS2 promoter] CTD PMID:17872375 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888
JBrowse link
G Crispld2 cysteine-rich secretory protein LCCL domain containing 2 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of CRISPLD2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CRISPLD2 mRNA CTD PMID:19059307 NCBI chr19:48,053,153...48,111,485
Ensembl chr19:48,053,287...48,110,465
JBrowse link
G Crybb2 crystallin, beta B2 affects expression EXP Raloxifene Hydrochloride affects the expression of CRYBB2 mRNA CTD PMID:16079270 NCBI chr12:43,569,747...43,579,671
Ensembl chr12:43,569,747...43,579,671
JBrowse link
G Csdc2 cold shock domain containing C2 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CSDC2 mRNA CTD PMID:19059307 NCBI chr 7:113,451,998...113,466,464
Ensembl chr 7:113,451,998...113,466,463
JBrowse link
G Csf1 colony stimulating factor 1 increases expression ISO Raloxifene Hydrochloride results in increased expression of CSF1 mRNA CTD PMID:12154049 NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704
JBrowse link
G Csf1r colony stimulating factor 1 receptor multiple interactions EXP [9,10-Dimethyl-1,2-benzanthracene co-treated with Raloxifene Hydrochloride co-treated with Fluoxetine] affects the expression of CSF1R protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with Raloxifene Hydrochloride] affects the expression of CSF1R protein CTD PMID:31332895 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of CSF2 mRNA CTD PMID:19059307 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Csf3 colony stimulating factor 3 decreases expression ISO Raloxifene Hydrochloride results in decreased expression of CSF3 mRNA CTD PMID:16298037 NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions
increases expression
ISO
EXP
[APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of CTNNB1 mRNA; IWR-1 compound inhibits the reaction [Raloxifene Hydrochloride inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CTNNB1 protein]]; Raloxifene Hydrochloride inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CTNNB1 protein]
Raloxifene Hydrochloride results in increased expression of CTNNB1 protein
[Raloxifene Hydrochloride co-treated with Bexarotene] affects the reaction [Azoxymethane affects the expression of CTNNB1 mRNA]; [Raloxifene Hydrochloride co-treated with Bexarotene] affects the reaction [Azoxymethane affects the expression of CTNNB1 protein]
CTD PMID:24080207 PMID:24431404 PMID:25571714 PMID:31470850 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Ctsb cathepsin B affects expression EXP Raloxifene Hydrochloride affects the expression of CTSB mRNA CTD PMID:16079270 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
JBrowse link
G Ctsh cathepsin H increases expression ISO Raloxifene Hydrochloride results in increased expression of CTSH mRNA CTD PMID:16514628 NCBI chr 8:90,608,941...90,627,824
Ensembl chr 8:90,608,941...90,627,824
JBrowse link
G Ctsk cathepsin K affects expression ISO Raloxifene Hydrochloride affects the expression of CTSK mRNA CTD PMID:17166402 NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550
JBrowse link
G Cuedc1 CUE domain containing 1 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CUEDC1 mRNA CTD PMID:19059307 NCBI chr10:72,892,637...72,986,546
Ensembl chr10:72,892,637...72,986,542
JBrowse link
G Cxadr CXADR, Ig-like cell adhesion molecule affects expression ISO Raloxifene Hydrochloride affects the expression of CXADR mRNA CTD PMID:14699072 NCBI chr11:16,982,864...17,030,078
Ensembl chr11:16,982,860...17,030,046
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions ISO Raloxifene Hydrochloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of CXCL10 mRNA]; Raloxifene Hydrochloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of CXCL10 protein] CTD PMID:19533603 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 multiple interactions
decreases expression
ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CXCL12 mRNA; Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of CXCL12 mRNA]; Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased secretion of CXCL12 protein]
Raloxifene Hydrochloride results in decreased expression of CXCL12 mRNA
CTD PMID:19059307 PMID:20549624 PMID:21185374 PMID:26865669 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions EXP Raloxifene Hydrochloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of CXCL2 mRNA] CTD PMID:25305410 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cylc2 cylicin 2 increases expression ISO Raloxifene Hydrochloride results in increased expression of CYLC2 mRNA CTD PMID:19429434 NCBI chr 5:65,554,320...65,576,251
Ensembl chr 5:65,554,309...65,589,282
JBrowse link
G Cyld CYLD lysine 63 deubiquitinase increases expression
multiple interactions
ISO Raloxifene Hydrochloride results in increased expression of CYLD mRNA
[SOD1 protein mutant form affects the susceptibility to Raloxifene Hydrochloride] which results in decreased expression of CYLD mRNA
CTD PMID:33269387 NCBI chr19:18,310,632...18,373,696
Ensembl chr19:18,314,019...18,373,658
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 multiple interactions
decreases expression
ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CYP19A1 mRNA
Raloxifene Hydrochloride results in decreased expression of CYP19A1 mRNA
CTD PMID:10704911 PMID:19059307 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
ISO
EXP
[Raloxifene Hydrochloride results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA; Raloxifene Hydrochloride inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]
Raloxifene Hydrochloride results in increased expression of CYP1A1 mRNA; Raloxifene Hydrochloride results in increased expression of CYP1A1 protein
ARNT protein affects the reaction [Raloxifene Hydrochloride results in increased expression of CYP1A1 protein]
CTD PMID:18493746 PMID:19901195 PMID:24481452 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CYP24A1 mRNA CTD PMID:19059307 NCBI chr 3:159,275,947...159,290,383
Ensembl chr 3:159,275,947...159,290,383
JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 decreases expression ISO Raloxifene Hydrochloride results in decreased expression of CYP26A1 mRNA CTD PMID:29990529 NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204
JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CYP26B1 mRNA CTD PMID:19059307 NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 affects expression EXP Raloxifene Hydrochloride affects the expression of CYP27A1 mRNA CTD PMID:16079270 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 increases expression ISO Raloxifene Hydrochloride results in increased expression of CYP27B1 mRNA CTD PMID:15795327 NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241
JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 affects expression EXP Raloxifene Hydrochloride affects the expression of CYP2A1 mRNA CTD PMID:16079270 NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 decreases activity ISO Raloxifene Hydrochloride results in decreased activity of CYP2C8 protein CTD PMID:15601807
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases activity
multiple interactions
ISO Raloxifene Hydrochloride results in decreased activity of CYP3A4 protein
Raloxifene Hydrochloride inhibits the reaction [CYP3A4 protein results in increased oxidation of 7-benzyloxy-4-trifluoromethylcoumarin]
CTD PMID:15860655 PMID:19299527 PMID:23721565 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Dact1 dishevelled-binding antagonist of beta-catenin 1 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of DACT1 mRNA CTD PMID:19059307 NCBI chr 6:89,790,676...89,818,254
Ensembl chr 6:89,790,644...89,817,906
JBrowse link
G Dag1 dystroglycan 1 increases expression ISO Raloxifene Hydrochloride results in increased expression of DAG1 mRNA CTD PMID:16497877 NCBI chr 8:108,890,926...108,955,611
Ensembl chr 8:108,890,929...108,952,325
JBrowse link
G Daxx death-domain associated protein affects expression ISO Raloxifene Hydrochloride affects the expression of DAXX mRNA CTD PMID:14699072 NCBI chr20:4,970,090...4,976,145
Ensembl chr20:4,970,092...4,975,843
JBrowse link
G Dbp D-box binding PAR bZIP transcription factor increases expression EXP Raloxifene Hydrochloride results in increased expression of DBP mRNA CTD PMID:15576828 NCBI chr 1:96,175,796...96,180,745
Ensembl chr 1:96,175,440...96,180,745
JBrowse link
G Dcbld2 discoidin, CUB and LCCL domain containing 2 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of DCBLD2 mRNA CTD PMID:19059307 NCBI chr11:42,125,525...42,179,927
Ensembl chr11:42,125,787...42,179,697
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 affects expression ISO Raloxifene Hydrochloride affects the expression of DDIT4 mRNA CTD PMID:14699072 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
JBrowse link
G Ddx21 DExD-box helicase 21 decreases expression ISO Raloxifene Hydrochloride results in decreased expression of DDX21 mRNA CTD PMID:16514628 NCBI chr20:30,534,319...30,554,513
Ensembl chr20:30,534,319...30,554,543
JBrowse link
G Ddx3y DEAD box helicase 3, Y-linked decreases expression ISO Raloxifene Hydrochloride results in decreased expression of DDX3Y mRNA CTD PMID:16514628 NCBI chr  Y:1,115,095...1,135,754
Ensembl chr  Y:1,116,309...1,135,706
JBrowse link
G Ddx50 DExD-box helicase 50 affects expression EXP Raloxifene Hydrochloride affects the expression of DDX50 mRNA CTD PMID:16079270 NCBI chr20:30,561,623...30,591,324
Ensembl chr20:30,560,544...30,591,152
JBrowse link
G Defb1 defensin beta 1 multiple interactions ISO [Progesterone co-treated with Raloxifene Hydrochloride] results in increased expression of DEFB1 mRNA CTD PMID:18367319 NCBI chr16:70,298,862...70,313,604
Ensembl chr16:70,298,863...70,313,604
JBrowse link
G Depp1 DEPP autophagy regulator 1 decreases expression ISO Raloxifene Hydrochloride results in decreased expression of DEPP1 mRNA CTD PMID:16298037 NCBI chr 4:149,910,794...149,913,013
Ensembl chr 4:149,910,779...149,914,542
JBrowse link
G Desi2 desumoylating isopeptidase 2 increases expression ISO Raloxifene Hydrochloride results in increased expression of DESI2 mRNA CTD PMID:33269387 NCBI chr13:89,961,767...90,011,255
Ensembl chr13:89,961,934...90,016,416
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase decreases expression ISO Raloxifene Hydrochloride results in decreased expression of DHCR24 mRNA CTD PMID:15585566 NCBI chr 5:121,344,552...121,371,124
Ensembl chr 5:121,344,575...121,371,137
JBrowse link
G Dhrs2 dehydrogenase/reductase 2 multiple interactions ISO Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of DHRS2 mRNA] CTD PMID:21185374 NCBI chr15:28,688,881...28,703,646
Ensembl chr15:28,688,940...28,703,644
JBrowse link
G Dhx9 DExH-box helicase 9 decreases expression ISO Raloxifene Hydrochloride results in decreased expression of DHX9 mRNA CTD PMID:16514628 NCBI chr13:65,602,322...65,639,098
Ensembl chr13:65,602,323...65,639,069
JBrowse link
G Dicer1 dicer 1 ribonuclease III decreases expression ISO Raloxifene Hydrochloride results in decreased expression of DICER1 mRNA CTD PMID:16497877 NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965
JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 decreases expression ISO Raloxifene Hydrochloride results in decreased expression of DKK1 protein CTD PMID:22067277 NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202
JBrowse link
G Dkk2 dickkopf WNT signaling pathway inhibitor 2 decreases expression ISO Raloxifene Hydrochloride results in decreased expression of DKK2 mRNA CTD PMID:19429434 NCBI chr 2:220,568,338...220,660,225
Ensembl chr 2:220,568,338...220,660,225
JBrowse link
G Dmbt1 deleted in malignant brain tumors 1 increases expression EXP
ISO
Raloxifene Hydrochloride results in increased expression of DMBT1 mRNA; Raloxifene Hydrochloride results in increased expression of DMBT1 protein CTD PMID:15564322 NCBI chr 1:185,617,469...185,696,476
Ensembl chr 1:185,617,294...185,696,478
JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 decreases expression ISO Raloxifene Hydrochloride results in decreased expression of DNAJA1 mRNA CTD PMID:16514628 NCBI chr 5:55,842,414...55,853,326
Ensembl chr 5:55,842,426...55,853,967
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 increases expression ISO Raloxifene Hydrochloride results in increased expression of DNAJB1 mRNA CTD PMID:16497877 NCBI chr19:24,522,731...24,526,419
Ensembl chr19:24,522,717...24,526,458
JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 increases expression ISO Raloxifene Hydrochloride results in increased expression of DNAJB4 mRNA CTD PMID:16497877 NCBI chr 2:241,129,346...241,159,272
Ensembl chr 2:241,130,340...241,159,089
JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 increases expression ISO Raloxifene Hydrochloride results in increased expression of DNAJB9 mRNA CTD PMID:16497877 NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063
JBrowse link
G Dnmbp dynamin binding protein affects expression ISO Raloxifene Hydrochloride affects the expression of DNMBP mRNA CTD PMID:14699072 NCBI chr 1:242,736,189...242,829,431
Ensembl chr 1:242,736,189...242,802,604
JBrowse link
G Dock9 dedicator of cytokinesis 9 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of DOCK9 mRNA CTD PMID:19059307 NCBI chr15:98,611,518...98,883,306
Ensembl chr15:98,618,084...98,883,153
JBrowse link
G Dram1 DNA-damage regulated autophagy modulator 1 multiple interactions ISO Raloxifene Hydrochloride inhibits the reaction [Estradiol results in decreased expression of DRAM1 mRNA] CTD PMID:21185374 NCBI chr 7:22,742,794...22,776,888
Ensembl chr 7:22,742,849...22,776,765
JBrowse link
G Drd5 dopamine receptor D5 increases expression ISO Raloxifene Hydrochloride results in increased expression of DRD5 mRNA CTD PMID:19429434 NCBI chr14:72,487,950...72,491,050
Ensembl chr14:72,489,347...72,490,774
JBrowse link
G Dusp2 dual specificity phosphatase 2 decreases expression
multiple interactions
ISO Raloxifene Hydrochloride results in decreased expression of DUSP2 mRNA
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of DUSP2 mRNA
CTD PMID:16497877 PMID:19059307 NCBI chr 3:114,556,325...114,558,510
Ensembl chr 3:114,556,325...114,558,499
JBrowse link
G Dusp4 dual specificity phosphatase 4 decreases expression ISO Raloxifene Hydrochloride results in decreased expression of DUSP4 mRNA CTD PMID:16497877 NCBI chr16:57,376,659...57,398,161
Ensembl chr16:57,377,229...57,398,138
JBrowse link
G Dusp5 dual specificity phosphatase 5 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of DUSP5 mRNA CTD PMID:19059307 NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818
JBrowse link
G Dusp6 dual specificity phosphatase 6 affects expression EXP Raloxifene Hydrochloride affects the expression of DUSP6 mRNA CTD PMID:16079270 NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185
JBrowse link
G Dync1li2 dynein, cytoplasmic 1 light intermediate chain 2 affects expression ISO Raloxifene Hydrochloride affects the expression of DYNC1LI2 mRNA CTD PMID:14699072 NCBI chr19:531,783...554,670
Ensembl chr19:531,812...554,670
JBrowse link
G Dynll1 dynein light chain LC8-type 1 increases expression ISO Raloxifene Hydrochloride results in increased expression of DYNLL1 mRNA CTD PMID:12154049 NCBI chr12:41,312,365...41,316,157
Ensembl chr12:41,312,367...41,314,741
JBrowse link
G Dyrk2 dual specificity tyrosine phosphorylation regulated kinase 2 increases expression ISO Raloxifene Hydrochloride results in increased expression of DYRK2 mRNA CTD PMID:26865669 NCBI chr 7:54,348,724...54,381,363
Ensembl chr 7:54,349,610...54,380,106
JBrowse link
G E2f1 E2F transcription factor 1 multiple interactions ISO [Raloxifene Hydrochloride co-treated with PX-866] results in decreased expression of E2F1 mRNA CTD PMID:26660119 NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361
JBrowse link
G E2f2 E2F transcription factor 2 increases expression ISO Raloxifene Hydrochloride results in increased expression of E2F2 mRNA CTD PMID:16497877 NCBI chr 5:148,399,193...148,422,595
Ensembl chr 5:148,399,642...148,421,217
JBrowse link
G Eci1 enoyl-CoA delta isomerase 1 affects expression EXP Raloxifene Hydrochloride affects the expression of ECI1 mRNA CTD PMID:16079270 NCBI chr10:13,456,715...13,470,061
Ensembl chr10:13,456,563...13,470,061
JBrowse link
G Edn3 endothelin 3 affects expression
multiple interactions
ISO Raloxifene Hydrochloride affects the expression of EDN3 mRNA
ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of EDN3 mRNA]
CTD PMID:14699072 NCBI chr 3:163,562,307...163,586,636
Ensembl chr 3:163,562,520...163,585,093
JBrowse link
G Ednra endothelin receptor type A multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of EDNRA mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of EDNRA mRNA CTD PMID:19059307 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
JBrowse link
G Efemp1 EGF containing fibulin extracellular matrix protein 1 affects expression
multiple interactions
ISO Raloxifene Hydrochloride affects the expression of EFEMP1 mRNA
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in decreased expression of EFEMP1 mRNA]
CTD PMID:14699072 PMID:21185374 NCBI chr14:102,610,813...102,690,027
Ensembl chr14:102,610,908...102,690,018
JBrowse link
G Efna1 ephrin A1 increases expression ISO Raloxifene Hydrochloride results in increased expression of EFNA1 mRNA CTD PMID:26865669 NCBI chr 2:174,681,676...174,689,061
Ensembl chr 2:174,681,682...174,690,866
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions
increases phosphorylation
decreases phosphorylation
ISO
EXP
[Raloxifene Hydrochloride co-treated with epigallocatechin gallate] results in decreased phosphorylation of EGFR protein; Raloxifene Hydrochloride results in decreased expression of and affects the localization of EGFR protein
Raloxifene Hydrochloride results in increased phosphorylation of EGFR protein
Raloxifene Hydrochloride results in decreased phosphorylation of EGFR protein
CTD PMID:18371987 PMID:23842642 PMID:24782323 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 affects expression EXP Raloxifene Hydrochloride affects the expression of EGLN3 mRNA CTD PMID:16079270 NCBI chr 6:71,650,297...71,675,766
Ensembl chr 6:71,650,297...71,675,766
JBrowse link
G Egr1 early growth response 1 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of EGR1 mRNA CTD PMID:19059307 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Egr3 early growth response 3 multiple interactions
decreases expression
ISO Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of EGR3 mRNA]
Raloxifene Hydrochloride results in decreased expression of EGR3 mRNA
CTD PMID:21185374 PMID:26865669 NCBI chr15:45,150,335...45,156,052
Ensembl chr15:45,150,567...45,154,627
JBrowse link
G Eif1 eukaryotic translation initiation factor 1 multiple interactions
increases expression
ISO [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of EIF1 mRNA
Raloxifene Hydrochloride results in increased expression of EIF1 mRNA
CTD PMID:16497877 PMID:19059307 NCBI chr10:85,246,751...85,248,842
Ensembl chr10:85,246,764...85,427,327
Ensembl chr 5:85,246,764...85,427,327
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha decreases expression ISO Raloxifene Hydrochloride results in decreased expression of EIF2S1 mRNA CTD PMID:16514628 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
JBrowse link
G Eif5 eukaryotic translation initiation factor 5 decreases expression ISO Raloxifene Hydrochloride results in decreased expression of EIF5 mRNA CTD PMID:16514628 NCBI chr 6:130,589,162...130,597,656
Ensembl chr 6:130,589,143...130,597,656
JBrowse link
G Eif5a eukaryotic translation initiation factor 5A decreases expression ISO Raloxifene Hydrochloride results in decreased expression of EIF5A mRNA CTD PMID:16497877 NCBI chr10:54,640,104...54,644,845
Ensembl chr10:54,640,024...54,644,656
JBrowse link
G Elf3 E74 like ETS transcription factor 3 multiple interactions
increases expression
ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ELF3 mRNA
Raloxifene Hydrochloride results in increased expression of ELF3 mRNA
CTD PMID:16202921 PMID:19059307 NCBI chr13:46,690,460...46,695,394
Ensembl chr13:46,690,466...46,695,481
JBrowse link
G Ell elongation factor for RNA polymerase II increases expression ISO Raloxifene Hydrochloride results in increased expression of ELL mRNA CTD PMID:15849065 NCBI chr16:18,843,775...18,891,484
Ensembl chr16:18,843,780...18,891,118
JBrowse link
G Elob elongin B decreases expression ISO Raloxifene Hydrochloride results in decreased expression of ELOB mRNA CTD PMID:16514628 NCBI chr10:12,848,830...12,853,897
Ensembl chr10:12,848,827...12,853,635
JBrowse link
G Elovl5 ELOVL fatty acid elongase 5 decreases expression ISO Raloxifene Hydrochloride results in decreased expression of ELOVL5 mRNA CTD PMID:16514628 NCBI chr 8:78,790,846...78,857,307
Ensembl chr 8:78,790,846...78,857,284
JBrowse link
G Emp1 epithelial membrane protein 1 multiple interactions ISO ESR1 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of EMP1 mRNA] CTD PMID:14699072 NCBI chr 4:168,212,901...168,233,039
Ensembl chr 4:168,212,861...168,232,904
JBrowse link
G Enc1 ectodermal-neural cortex 1 affects expression
multiple interactions
ISO Raloxifene Hydrochloride affects the expression of ENC1 mRNA
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of ENC1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ENC1 mRNA
CTD PMID:14699072 PMID:19059307 NCBI chr 2:28,550,670...28,562,591
Ensembl chr 2:28,550,464...28,562,713
JBrowse link
G Endod1 endonuclease domain containing 1 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ENDOD1 mRNA CTD PMID:19059307 NCBI chr 8:11,209,113...11,238,507
Ensembl chr 8:11,211,110...11,238,892
JBrowse link
G Eng endoglin increases expression ISO Raloxifene Hydrochloride results in increased expression of ENG mRNA; Raloxifene Hydrochloride results in increased expression of ENG protein CTD PMID:20135064 PMID:32947957 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230
JBrowse link
G Eno2 enolase 2 affects expression ISO Raloxifene Hydrochloride affects the expression of ENO2 mRNA CTD PMID:14699072 NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980
JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 multiple interactions
affects expression
ISO [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of ENPP2 mRNA
Raloxifene Hydrochloride affects the expression of ENPP2 mRNA
CTD PMID:14699072 PMID:19059307 NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827
JBrowse link
G Entpd2 ectonucleoside triphosphate diphosphohydrolase 2 increases expression EXP Raloxifene Hydrochloride results in increased expression of ENTPD2 mRNA CTD PMID:15576828 NCBI chr 3:8,213,575...8,219,094
Ensembl chr 3:8,213,663...8,226,866
JBrowse link
G Epcam epithelial cell adhesion molecule multiple interactions ISO [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of EPCAM mRNA; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of EPCAM protein CTD PMID:24431404 NCBI chr 6:6,880,142...6,896,103
Ensembl chr 6:6,878,237...6,896,127
JBrowse link
G Epha1 Eph receptor A1 increases expression ISO Raloxifene Hydrochloride results in increased expression of EPHA1 mRNA CTD PMID:12154049 NCBI chr 4:71,246,409...71,260,920
Ensembl chr 4:71,246,409...71,260,846
JBrowse link
G Epha4 Eph receptor A4 increases expression ISO Raloxifene Hydrochloride results in increased expression of EPHA4 mRNA CTD PMID:26865669 NCBI chr 9:78,815,460...78,958,139
Ensembl chr 9:78,815,460...78,958,139
JBrowse link
G Epor erythropoietin receptor affects expression ISO Raloxifene Hydrochloride affects the expression of EPOR mRNA CTD PMID:14699072 NCBI chr 8:20,489,678...20,494,257
Ensembl chr 8:20,489,678...20,494,257
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 decreases response to substance ISO ERBB2 protein results in decreased susceptibility to Raloxifene Hydrochloride CTD PMID:16609042 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 affects expression ISO Raloxifene Hydrochloride affects the expression of ERBB3 mRNA CTD PMID:14699072 NCBI chr 7:994,549...1,015,876
Ensembl chr 7:996,225...1,015,525
JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 multiple interactions ISO Raloxifene Hydrochloride inhibits the reaction [Estradiol results in decreased expression of ERBB4 mRNA] CTD PMID:21185374 NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595
JBrowse link
G Esr1 estrogen receptor 1 affects response to substance
increases response to substance
multiple interactions
affects folding
affects binding
decreases activity
decreases expression
increases expression
affects expression
ISO
EXP
ESR1 gene polymorphism affects the susceptibility to Raloxifene Hydrochloride
ESR1 exon polymorphism results in increased susceptibility to Raloxifene Hydrochloride
[ESR1 protein co-treated with ESR2 protein] affects the reaction [Raloxifene Hydrochloride results in increased cleavage of PARP1 protein]; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of ANKRD28 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of CCN3 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of CSF2 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of ENC1 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of HAS2 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of KCNN4 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of LINC00312 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of LMCD1 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of PLAU mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of RGS16 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of SLN mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of TGFBI mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of TNFRSF11B mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of TXNIP mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of CA12 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of CRISPLD2 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of EDNRA mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of EIF1 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of ENPP2 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of FHL2 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of G0S2 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of GRK5 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of HEG1 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of HK1 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of IDH2 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of ISG20 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of KCTD12 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of KLRC2 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of LPL mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of MSMB mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of NLRP3 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of NPR2 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of OSBPL3 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of PFKFB3 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of PTPRE mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of RASGRP1 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of RET mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of RGS4 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of RHOBTB3 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of RIPOR2 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of SEMA3B mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of SGK1 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of SYBU mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of TIPARP mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of TMOD1 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of TMPRSS3 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of ZNF395 mRNA; ARID5A protein inhibits the reaction [Raloxifene Hydrochloride results in increased activity of ESR1 protein]; ESR1 protein affects the reaction [Raloxifene Hydrochloride affects the localization of FOXO3 protein]; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of EMP1 mRNA]; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of HSPA1B mRNA]; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of MFAP5 mRNA]; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in decreased secretion of IL6 protein]; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of IDH2 mRNA]; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of KLRC2 mRNA]; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of KLRC3 mRNA]; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of PLPP3 mRNA]; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of TGFB3 mRNA]; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of ZFP36 mRNA]; ESR1 protein promotes the reaction [Raloxifene Hydrochloride results in increased activity of TERT protein]; Raloxifene Hydrochloride affects the folding of and affects the activity of ESR1 protein; Raloxifene Hydrochloride binds to and affects the activity of ESR1 protein; Raloxifene Hydrochloride binds to and results in decreased activity of ESR1 protein; Raloxifene Hydrochloride inhibits the reaction [ESR1 protein binds to CCL3 promoter]; Raloxifene Hydrochloride inhibits the reaction [ESR1 protein binds to RELA protein]; Raloxifene Hydrochloride inhibits the reaction [Estradiol binds to ESR1 protein]; Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of ESR1 protein]; Raloxifene Hydrochloride inhibits the reaction [trichostatin A results in decreased expression of ESR1 mRNA]; Raloxifene Hydrochloride promotes the reaction [ESR1 protein binds to IGF1 promoter]; Raloxifene Hydrochloride promotes the reaction [ESR1 protein binds to KLRC3 gene]; Raloxifene Hydrochloride promotes the reaction [ESR1 protein binds to PTGS2 promoter]; Raloxifene Hydrochloride results in increased activity of and affects the localization of ESR1 protein
Raloxifene Hydrochloride affects the folding of ESR1 protein
[Raloxifene Hydrochloride binds to ESR1 protein] which binds to SERPINB9 protein; [Raloxifene Hydrochloride binds to ESR1 protein] which binds to TFF1 protein; Raloxifene Hydrochloride binds to ESR1 protein
Raloxifene Hydrochloride results in decreased activity of ESR1 protein
Raloxifene Hydrochloride results in decreased expression of ESR1 mRNA; Raloxifene Hydrochloride results in decreased expression of ESR1 protein
Raloxifene Hydrochloride results in increased expression of ESR1 mRNA; Raloxifene Hydrochloride results in increased expression of ESR1 protein
ESR1 protein promotes the reaction [Raloxifene Hydrochloride results in increased expression of SLC1A2 mRNA]; ESR1 protein promotes the reaction [Raloxifene Hydrochloride results in increased expression of SLC1A3 mRNA]
Raloxifene Hydrochloride metabolite binds to ESR1 protein
Raloxifene Hydrochloride affects the expression of ESR1 mRNA
[Raloxifene Hydrochloride co-treated with Estradiol] results in decreased expression of ESR1 protein; [Raloxifene Hydrochloride co-treated with Oxygen deficiency] results in increased expression of ESR1 protein; Raloxifene Hydrochloride affects the reaction [Oxygen deficiency affects the expression of ESR1 protein alternative form]; Raloxifene Hydrochloride binds to and affects the folding of ESR1 protein mutant form; Raloxifene Hydrochloride inhibits the reaction [Oxygen deficiency results in decreased expression of ESR1 mRNA]
CTD PMID:9751507 PMID:11535548 PMID:11867264 PMID:14617632 PMID:14699072 More... NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions
increases response to substance
decreases activity
increases activity
affects expression
increases expression
ISO
EXP
[ESR1 protein co-treated with ESR2 protein] affects the reaction [Raloxifene Hydrochloride results in increased cleavage of PARP1 protein]; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ABCC1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ACKR3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ACSL1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of AGO2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of AKAP1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ARL4C mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ASB13 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of C14ORF132 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of C2CD2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CA12 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CALM1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CASKIN2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CASP7 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CCND1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CDK5R1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CEBPB mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CERS6 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CLCN4 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CRISPLD2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CSDC2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CUEDC1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CYP19A1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CYP24A1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CYP26B1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of DOCK9 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of EDNRA mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ELF3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ENDOD1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of EVI2A mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FADD mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FGD6 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FGFR2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FHL2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FLNB mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FOSL2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FOXO1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FST mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of GPRC5C mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HEG1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HK1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HMOX1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HPCAL1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HSPB8 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HTR3A mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of INPP5A mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of IVL mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of KAZN mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of KCTD12 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of KIF3C mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of KLRC3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of KLRK1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of LBH mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of LMNB2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of LRIG1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of LRRC20 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of LYSMD4 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MAFF mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MAGEA8 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MAP3K5 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MAP3K8 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MAPKAPK2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MBNL2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MDFIC mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MEF2A mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MMP12 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MN1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MPPED2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MYT1L mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NAV2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NCF2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NCOA1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NCOA4 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NDRG4 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NFATC1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NFIL3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NFKBIA mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NINJ1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NPR2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NR1D1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NR2F6 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NUAK1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of OSBPL3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of OTUB2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PCTP mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PDLIM3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PHC2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PHF11 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PITPNC1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PRKCZ mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PTGER3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PTGES mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of RCOR3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of RET mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of RETREG1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of RFTN1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of RGL1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of RHOF mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of RPS6KA2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SALL1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SCNN1A mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SEMA3F mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SERPINB6 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SLC18A3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SREBF1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SSH1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ST3GAL1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of STK24 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SYBU mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SYNJ2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SYNPO mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of TACC1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of TACC2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of TBXA2R mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of TGFA mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of TMOD1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of TNS3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of TOB1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of TRAF3IP2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of UPF1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of WNT5A mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ZCCHC24 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ZMIZ1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ZNF395 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ADAM19 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ADORA2B mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of AMIGO2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ANKRD1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of AREG mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ATF3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of BIRC3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CCL2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CCL20 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CDH2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CDO1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CXCL12 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CXCL8 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of DACT1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of DCBLD2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of DUSP2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of DUSP5 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of EGR1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ENC1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of FUT9 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of GAD1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of GRB10 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of GYG1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of HBEGF mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ID4 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of IFNGR2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of INHBA mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of JAG1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of KRT17 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of KRT34 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of LDLRAD4 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of LMCD1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of MAP2K3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of NAB1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of NFKBIE mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of NR3C1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of NR4A3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of OCLN mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of PCDH7 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of PDP1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of PTGS2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of PTP4A3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of PTX3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of RASGRP1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of RCAN2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of RFK mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of RGS4 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of RRAD mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of SERPINE1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of SLCO4C1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of SOD2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TCIM mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TGFB2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TGFBI mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TMEM158 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TNC mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TNFRSF11B mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TNFRSF21 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TNIK mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TRAF5 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TRIB1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TRIM36 mRNA; [trichostatin A co-treated with Estradiol co-treated with Raloxifene Hydrochloride] results in increased expression of ESR2 protein; [trichostatin A co-treated with Raloxifene Hydrochloride] results in increased expression of ESR2 mRNA; [trichostatin A co-treated with Raloxifene Hydrochloride] results in increased expression of ESR2 protein; ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of EDN3 mRNA]; ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of FLNB mRNA]; ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of IER3 mRNA]; ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of KLRC2 mRNA]; ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of MSMB mRNA]; ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of NCF2 mRNA]; ESR2 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of GABRR1 mRNA]; ESR2 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of TMT1A mRNA]; ESR2 protein promotes the reaction [Raloxifene Hydrochloride results in increased activity of TERT protein]; Raloxifene Hydrochloride binds to and results in increased activity of ESR2 protein; Raloxifene Hydrochloride inhibits the reaction [3,3'-diindolylmethane results in increased expression of ESR2 mRNA]; Raloxifene Hydrochloride promotes the reaction [[trichostatin A co-treated with Estradiol] results in increased expression of ESR2 mRNA]; Raloxifene Hydrochloride promotes the reaction [ESR2 protein binds to ESR2 protein]; Raloxifene Hydrochloride promotes the reaction [ESR2 protein binds to IGF1 promoter]; Raloxifene Hydrochloride promotes the reaction [ESR2 protein binds to PTGS2 promoter]
ESR2 protein results in increased susceptibility to Raloxifene Hydrochloride
Raloxifene Hydrochloride results in decreased activity of ESR2 protein
Raloxifene Hydrochloride results in increased activity of ESR2 protein
[APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of ESR2 protein; ESR2 protein affects the reaction [Raloxifene Hydrochloride inhibits the reaction [Streptozocin results in decreased secretion of MMP2 protein]]; Raloxifene Hydrochloride binds to and affects the activity of ESR2 protein alternative form; Raloxifene Hydrochloride inhibits the reaction [Oxygen deficiency results in increased expression of ESR2 mRNA]; Raloxifene Hydrochloride inhibits the reaction [Oxygen deficiency results in increased expression of ESR2 protein]
[Raloxifene Hydrochloride co-treated with Bexarotene] affects the reaction [Azoxymethane affects the expression of ESR2 mRNA]; [Raloxifene Hydrochloride co-treated with Bexarotene] affects the reaction [Azoxymethane affects the expression of ESR2 protein]; ESR2 protein promotes the reaction [Raloxifene Hydrochloride results in increased expression of SLC1A2 mRNA]; ESR2 protein promotes the reaction [Raloxifene Hydrochloride results in increased expression of SLC1A3 mRNA]; Raloxifene Hydrochloride affects the reaction [Azoxymethane affects the expression of ESR2 mRNA]; Raloxifene Hydrochloride affects the reaction [Azoxymethane affects the expression of ESR2 protein]
Raloxifene Hydrochloride affects the expression of ESR2 mRNA
Raloxifene Hydrochloride results in increased expression of ESR2 protein
CTD PMID:14699072 PMID:15924412 PMID:16798746 PMID:17638070 PMID:17654759 More... NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Evi2a ecotropic viral integration site 2A multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of EVI2A mRNA CTD PMID:19059307 NCBI chr10:64,485,760...64,489,660
Ensembl chr10:64,485,200...64,489,843
JBrowse link
G F11 coagulation factor XI increases activity ISO Raloxifene Hydrochloride results in increased activity of F11 protein CTD PMID:16359964 NCBI chr16:46,987,988...47,009,015
Ensembl chr16:46,986,107...47,008,437
JBrowse link
G F12 coagulation factor XII increases activity ISO Raloxifene Hydrochloride results in increased activity of F12 protein CTD PMID:16359964 NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530
JBrowse link
G F13a1 coagulation factor XIII A1 chain affects expression ISO Raloxifene Hydrochloride affects the expression of F13A1 mRNA CTD PMID:14699072 NCBI chr17:27,815,723...27,992,494
Ensembl chr17:27,815,702...27,992,700
JBrowse link
G F2r coagulation factor II (thrombin) receptor increases expression ISO Raloxifene Hydrochloride results in increased expression of F2R mRNA CTD PMID:12154049 NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870
JBrowse link
G F8 coagulation factor VIII increases activity
increases expression
ISO Raloxifene Hydrochloride results in increased activity of F8 protein
Raloxifene Hydrochloride results in increased expression of F8 protein
CTD PMID:15850603 PMID:16359964 NCBI chr18:140,848...172,330
Ensembl chr18:140,955...171,857
JBrowse link
G Fabp4 fatty acid binding protein 4 increases expression
multiple interactions
ISO Raloxifene Hydrochloride results in increased expression of FABP4 mRNA
Raloxifene Hydrochloride affects the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of FABP4 protein]
CTD PMID:16643890 PMID:31470850 NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578
JBrowse link
G Fadd Fas associated via death domain multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FADD mRNA CTD PMID:19059307 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
JBrowse link
G Fam171b family with sequence similarity 171, member B multiple interactions ISO [Raloxifene Hydrochloride co-treated with Estradiol] results in increased expression of FAM171B mRNA CTD PMID:21185374 NCBI chr 3:68,930,755...68,986,113
Ensembl chr 3:68,930,822...68,986,127
JBrowse link
G Fap fibroblast activation protein, alpha affects expression ISO Raloxifene Hydrochloride affects the expression of FAP mRNA CTD PMID:14699072 NCBI chr 3:47,138,823...47,207,671
Ensembl chr 3:47,138,813...47,225,545
JBrowse link
G Fgd6 FYVE, RhoGEF and PH domain containing 6 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FGD6 mRNA CTD PMID:19059307 NCBI chr 7:28,597,609...28,712,908
Ensembl chr 7:28,597,609...28,712,456
JBrowse link
G Fgf8 fibroblast growth factor 8 increases expression ISO Raloxifene Hydrochloride results in increased expression of FGF8 mRNA CTD PMID:29990529 NCBI chr 1:244,584,477...244,590,578
Ensembl chr 1:244,584,652...244,590,359
JBrowse link
G Fgf9 fibroblast growth factor 9 affects expression EXP Raloxifene Hydrochloride affects the expression of FGF9 mRNA CTD PMID:16079270 NCBI chr15:32,208,993...32,254,952
Ensembl chr15:32,210,074...32,253,309
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FGFR2 mRNA CTD PMID:19059307 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626
JBrowse link
G Fhl1 four and a half LIM domains 1 multiple interactions ISO Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of FHL1 mRNA] CTD PMID:21185374 NCBI chr  X:134,555,399...134,614,930
Ensembl chr  X:134,555,479...134,614,928
JBrowse link
G Fhl2 four and a half LIM domains 2 multiple interactions
affects expression
decreases expression
ISO [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of FHL2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FHL2 mRNA
Raloxifene Hydrochloride affects the expression of FHL2 mRNA
Raloxifene Hydrochloride results in decreased expression of FHL2 mRNA
CTD PMID:14699072 PMID:19059307 PMID:26865669 NCBI chr 9:45,388,979...45,462,421
Ensembl chr 9:45,388,981...45,431,192
JBrowse link
G Fis1 fission, mitochondrial 1 affects expression
increases expression
EXP Raloxifene Hydrochloride affects the expression of FIS1 mRNA
Raloxifene Hydrochloride results in increased expression of FIS1 mRNA
CTD PMID:15576828 PMID:16079270 NCBI chr12:19,708,560...19,723,392
Ensembl chr12:19,708,558...19,723,377
JBrowse link
G Fkbp3 FKBP prolyl isomerase 3 affects expression EXP Raloxifene Hydrochloride affects the expression of FKBP3 mRNA CTD PMID:16079270 NCBI chr 6:83,113,885...83,125,500
Ensembl chr 6:83,113,786...83,127,011
JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 increases expression ISO Raloxifene Hydrochloride results in increased expression of FKBP5 mRNA CTD PMID:22217510 NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674
JBrowse link
G Flnb filamin B affects expression
multiple interactions
ISO Raloxifene Hydrochloride affects the expression of FLNB mRNA
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FLNB mRNA; ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of FLNB mRNA]
CTD PMID:14699072 PMID:19059307 NCBI chr15:16,961,999...17,095,059
Ensembl chr15:16,962,003...17,095,006
JBrowse link
G Flnc filamin C decreases expression ISO Raloxifene Hydrochloride results in decreased expression of FLNC mRNA CTD PMID:16514628 NCBI chr 4:58,034,088...58,061,882
Ensembl chr 4:58,034,189...58,061,844
JBrowse link
G Flrt1 fibronectin leucine rich transmembrane protein 1 affects expression ISO Raloxifene Hydrochloride affects the expression of FLRT1 mRNA CTD PMID:14699072 NCBI chr 1:204,275,785...204,292,844
Ensembl chr 1:204,275,367...204,353,750
JBrowse link
G Fmnl1 formin-like 1 affects expression ISO Raloxifene Hydrochloride affects the expression of FMNL1 mRNA CTD PMID:14699072 NCBI chr10:88,115,876...88,143,342
Ensembl chr10:88,116,009...88,143,357
JBrowse link
G Fn1 fibronectin 1 multiple interactions ISO Raloxifene Hydrochloride inhibits the reaction [TGFB1 protein results in increased expression of FN1 mRNA] CTD PMID:15920148 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FOSL2 mRNA CTD PMID:19059307 NCBI chr 6:24,297,898...24,319,219
Ensembl chr 6:24,300,956...24,320,034
JBrowse link
G Foxa2 forkhead box A2 increases expression ISO Raloxifene Hydrochloride results in increased expression of FOXA2 mRNA CTD PMID:23184660 NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326
JBrowse link
G Foxc1 forkhead box C1 decreases expression ISO Raloxifene Hydrochloride results in decreased expression of FOXC1 mRNA CTD PMID:26865669 NCBI chr17:32,631,379...32,635,361
Ensembl chr17:32,633,142...32,634,803
JBrowse link
G Foxe1 forkhead box E1 affects expression EXP Raloxifene Hydrochloride affects the expression of FOXE1 mRNA CTD PMID:16079270 NCBI chr 5:60,630,027...60,632,835
Ensembl chr 5:60,630,027...60,632,835
JBrowse link
G Foxo1 forkhead box O1 affects expression
multiple interactions
ISO Raloxifene Hydrochloride affects the expression of FOXO1 mRNA
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FOXO1 mRNA
CTD PMID:14699072 PMID:19059307 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
JBrowse link
G Foxo3 forkhead box O3 affects localization
multiple interactions
ISO Raloxifene Hydrochloride affects the localization of FOXO3 protein
ESR1 protein affects the reaction [Raloxifene Hydrochloride affects the localization of FOXO3 protein]; GPER1 protein affects the reaction [Raloxifene Hydrochloride affects the localization of FOXO3 protein]
CTD PMID:26470790 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
JBrowse link
G Fst follistatin affects expression
multiple interactions
ISO Raloxifene Hydrochloride affects the expression of FST mRNA
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FST mRNA
CTD PMID:14699072 PMID:19059307 NCBI chr 2:46,123,260...46,130,584
Ensembl chr 2:46,123,439...46,130,571
JBrowse link
G Fut9 fucosyltransferase 9 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of FUT9 mRNA CTD PMID:19059307 NCBI chr 5:39,351,815...39,565,256
Ensembl chr 5:39,351,819...39,565,130
JBrowse link
G Fyttd1 forty-two-three domain containing 1 decreases expression ISO Raloxifene Hydrochloride results in decreased expression of FYTTD1 mRNA CTD PMID:16514628 NCBI chr11:67,877,967...67,907,500
Ensembl chr11:67,877,967...67,907,511
JBrowse link
G Fzd6 frizzled class receptor 6 affects expression ISO Raloxifene Hydrochloride affects the expression of FZD6 mRNA CTD PMID:14699072 NCBI chr 7:70,055,012...70,086,781
Ensembl chr 7:70,055,068...70,086,776
JBrowse link
G G0s2 G0/G1switch 2 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of G0S2 mRNA CTD PMID:19059307 NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451
JBrowse link
G Gabarap GABA type A receptor-associated protein affects expression EXP Raloxifene Hydrochloride affects the expression of GABARAP mRNA CTD PMID:16079270 NCBI chr10:54,714,777...54,718,099
Ensembl chr10:54,714,198...54,717,765
JBrowse link
G Gabbr2 gamma-aminobutyric acid type B receptor subunit 2 multiple interactions ISO Raloxifene Hydrochloride promotes the reaction [Estradiol results in increased expression of GABBR2 mRNA] CTD PMID:21185374 NCBI chr 5:60,947,517...61,288,104
Ensembl chr 5:60,947,526...61,288,104
JBrowse link
G Gabpa GA binding protein transcription factor subunit alpha increases expression ISO Raloxifene Hydrochloride results in increased expression of GABPA mRNA CTD PMID:12154049 NCBI chr11:23,888,586...23,917,612
Ensembl chr11:23,888,815...23,917,605
JBrowse link
G Gabrg1 gamma-aminobutyric acid type A receptor subunit gamma 1 affects expression EXP Raloxifene Hydrochloride affects the expression of GABRG1 mRNA CTD PMID:16079270 NCBI chr14:37,396,217...37,469,606
Ensembl chr14:37,396,294...37,635,956
JBrowse link
G Gabrr1 gamma-aminobutyric acid type A receptor subunit rho 1 affects expression
multiple interactions
ISO Raloxifene Hydrochloride affects the expression of GABRR1 mRNA
ESR2 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of GABRR1 mRNA]
CTD PMID:14699072 NCBI chr 5:47,524,151...47,561,228
Ensembl chr 5:47,524,151...47,561,228
JBrowse link
G Gad1 glutamate decarboxylase 1 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of GAD1 mRNA CTD PMID:19059307 NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333
JBrowse link
G Gal galanin and GMAP prepropeptide decreases expression ISO Raloxifene Hydrochloride results in decreased expression of GAL mRNA CTD PMID:16202921 NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959
JBrowse link
G Gas6 growth arrest specific 6 increases expression
multiple interactions
affects expression
ISO
EXP
Raloxifene Hydrochloride results in increased expression of GAS6 mRNA
fulvestrant inhibits the reaction [Raloxifene Hydrochloride results in increased expression of GAS6 mRNA]
Raloxifene Hydrochloride affects the expression of GAS6 mRNA
CTD PMID:16079270 PMID:19429434 NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904
JBrowse link
G Gata2 GATA binding protein 2 increases expression ISO Raloxifene Hydrochloride results in increased expression of GATA2 mRNA CTD PMID:19429434 NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761
JBrowse link
G Gcnt1 glucosaminyl (N-acetyl) transferase 1 affects expression ISO Raloxifene Hydrochloride affects the expression of GCNT1 mRNA CTD PMID:14699072 NCBI chr 1:214,718,344...214,755,735
Ensembl chr 1:214,718,293...214,758,776
JBrowse link
G Gdf9 growth differentiation factor 9 increases expression ISO Raloxifene Hydrochloride results in increased expression of GDF9 mRNA CTD PMID:22841776 NCBI chr10:37,589,200...37,599,970
Ensembl chr10:37,595,679...37,599,672
JBrowse link
G Gfra2 GDNF family receptor alpha 2 increases expression EXP Raloxifene Hydrochloride results in increased expression of GFRA2 mRNA CTD PMID:15576828 NCBI chr15:45,941,841...46,033,715
Ensembl chr15:45,941,828...46,033,714
JBrowse link
G Gh1 growth hormone 1 multiple interactions ISO Raloxifene Hydrochloride promotes the reaction [GH1 protein results in increased phosphorylation of JAK2 protein] CTD PMID:17272397 NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078
JBrowse link
G Ghr growth hormone receptor decreases expression ISO Raloxifene Hydrochloride results in decreased expression of GHR mRNA CTD PMID:16202921 NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735
JBrowse link
G Ghrh growth hormone releasing hormone affects expression EXP Raloxifene Hydrochloride affects the expression of GHRH mRNA CTD PMID:16079270 NCBI chr 3:145,992,762...146,012,528
Ensembl chr 3:145,992,763...146,011,889
JBrowse link
G Ghrhr growth hormone releasing hormone receptor affects expression
affects response to substance
EXP
ISO
Raloxifene Hydrochloride affects the expression of GHRHR mRNA
GHRHR affects the susceptibility to Raloxifene Hydrochloride
CTD PMID:16079270 PMID:32934756 NCBI chr 4:84,498,159...84,532,851
Ensembl chr 4:84,500,212...84,532,776
JBrowse link
G Gjb2 gap junction protein, beta 2 increases expression ISO Raloxifene Hydrochloride results in increased expression of GJB2 mRNA CTD PMID:12370124 NCBI chr15:31,260,390...31,278,222
Ensembl chr15:31,260,357...31,278,177
JBrowse link
G Glrb glycine receptor, beta affects expression ISO Raloxifene Hydrochloride affects the expression of GLRB mRNA CTD PMID:14699072 NCBI chr 2:166,134,616...166,207,498
Ensembl chr 2:166,134,626...166,207,489
JBrowse link
G Glrx glutaredoxin affects expression ISO Raloxifene Hydrochloride affects the expression of GLRX mRNA CTD PMID:14699072 NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680
JBrowse link
G Glul glutamate-ammonia ligase affects expression EXP Raloxifene Hydrochloride affects the expression of GLUL mRNA CTD PMID:16079270 NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108
JBrowse link
G Glyat glycine-N-acyltransferase affects expression ISO Raloxifene Hydrochloride affects the expression of GLYAT mRNA CTD PMID:14699072 NCBI chr 1:209,704,213...209,724,949
Ensembl chr 1:209,704,268...209,724,942
JBrowse link
G Gnb1 G protein subunit beta 1 affects expression EXP Raloxifene Hydrochloride affects the expression of GNB1 mRNA CTD PMID:16079270 NCBI chr 5:166,075,508...166,142,223
Ensembl chr 5:166,075,629...166,142,124
JBrowse link
G Gnb4 G protein subunit beta 4 increases expression ISO Raloxifene Hydrochloride results in increased expression of GNB4 mRNA CTD PMID:19429434 NCBI chr 2:115,360,746...115,400,680
Ensembl chr 2:115,364,918...115,400,579
JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 multiple interactions ISO Raloxifene Hydrochloride inhibits the reaction [Estradiol promotes the reaction [GNRH1 protein results in increased secretion of PRL protein]] CTD PMID:17054466 NCBI chr15:41,972,482...41,976,690
Ensembl chr15:41,972,905...41,973,581
Ensembl chr15:41,972,905...41,973,581
JBrowse link
G Golga5 golgin A5 decreases expression ISO Raloxifene Hydrochloride results in decreased expression of GOLGA5 mRNA CTD PMID:16514628 NCBI chr 6:121,612,389...121,640,552
Ensembl chr 6:121,612,529...121,640,413
JBrowse link
G Gpc1 glypican 1 affects expression ISO Raloxifene Hydrochloride affects the expression of GPC1 mRNA CTD PMID:14699072 NCBI chr 9:93,396,234...93,424,047
Ensembl chr 9:93,396,234...93,424,047
JBrowse link
G Gpc3 glypican 3 increases expression EXP Raloxifene Hydrochloride results in increased expression of GPC3 mRNA CTD PMID:15576828 NCBI chr  X:131,868,986...132,236,824
Ensembl chr  X:131,868,990...132,236,798
JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 multiple interactions
increases activity
EXP
ISO
[4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline binds to and results in decreased activity of GPER1 protein] inhibits the reaction [[Raloxifene Hydrochloride results in increased activity of GPER1 protein] which results in increased expression of SLC1A2 protein]; [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline results in decreased activity of GPER1 protein] inhibits the reaction [[Raloxifene Hydrochloride results in increased activity of GPER1 protein] which results in increased expression of SLC1A3 protein]; [Raloxifene Hydrochloride results in increased activity of GPER1 protein] which results in increased expression of SLC1A2 protein; [Raloxifene Hydrochloride results in increased activity of GPER1 protein] which results in increased expression of SLC1A3 protein
GPER1 protein affects the reaction [Raloxifene Hydrochloride affects the localization of FOXO3 protein]; GPER1 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of AVP mRNA]; GPER1 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of MYC mRNA]
Raloxifene Hydrochloride inhibits the reaction [Oxygen deficiency results in increased expression of GPER1 mRNA]
CTD PMID:22453024 PMID:24782323 PMID:24846829 PMID:26200092 PMID:26470790 NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889
JBrowse link
G Gpnmb glycoprotein nmb multiple interactions ISO Raloxifene Hydrochloride inhibits the reaction [Estradiol results in decreased expression of GPNMB mRNA] CTD PMID:21185374 NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367
JBrowse link
G Gprc5c G protein-coupled receptor, class C, group 5, member C multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of GPRC5C mRNA CTD PMID:19059307 NCBI chr10:99,886,900...99,908,928
Ensembl chr10:99,887,077...99,908,926
JBrowse link
G Grb10 growth factor receptor bound protein 10 affects expression
multiple interactions
ISO Raloxifene Hydrochloride affects the expression of GRB10 mRNA
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of GRB10 mRNA
CTD PMID:14699072 PMID:19059307 NCBI chr14:86,495,051...86,602,800
Ensembl chr14:86,495,054...86,602,806
JBrowse link
G Greb1 growth regulating estrogen receptor binding 1 multiple interactions
decreases expression
ISO Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of GREB1 mRNA]
Raloxifene Hydrochloride results in decreased expression of GREB1 mRNA
CTD PMID:21185374 PMID:26879975 NCBI chr 6:39,440,522...39,562,364
Ensembl chr 6:39,440,504...39,581,633
JBrowse link
G Grhl1 grainyhead-like transcription factor 1 decreases expression ISO Raloxifene Hydrochloride results in decreased expression of GRHL1 mRNA CTD PMID:19429434 NCBI chr 6:41,207,325...41,257,516
Ensembl chr 6:41,207,348...41,254,301
JBrowse link
G Grina glutamate ionotropic receptor NMDA type subunit associated protein 1 affects expression EXP Raloxifene Hydrochloride affects the expression of GRINA mRNA CTD PMID:16079270 NCBI chr 7:107,962,194...107,965,372
Ensembl chr 7:107,962,207...107,965,366
JBrowse link
G Grk5 G protein-coupled receptor kinase 5 affects expression
multiple interactions
ISO Raloxifene Hydrochloride affects the expression of GRK5 mRNA
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of GRK5 mRNA
CTD PMID:14699072 PMID:19059307 NCBI chr 1:260,028,269...260,223,699
Ensembl chr 1:260,028,242...260,218,701
JBrowse link
G Gyg1 glycogenin 1 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of GYG1 mRNA CTD PMID:19059307 NCBI chr 2:102,611,888...102,653,916
Ensembl chr 2:102,598,496...102,653,797
JBrowse link
G H19 H19 imprinted maternally expressed transcript multiple interactions ISO Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of H19 mRNA] CTD PMID:21185374 NCBI chr 1:197,730,698...197,733,374
Ensembl chr 1:197,730,698...197,733,134
JBrowse link
G Hal histidine ammonia lyase affects expression EXP Raloxifene Hydrochloride affects the expression of HAL mRNA CTD PMID:16079270 NCBI chr 7:28,007,449...28,037,701
Ensembl chr 7:28,006,972...28,037,701
JBrowse link
G Hapln1 hyaluronan and proteoglycan link protein 1 affects expression ISO Raloxifene Hydrochloride affects the expression of HAPLN1 mRNA CTD PMID:14699072 NCBI chr 2:20,631,640...20,696,388
Ensembl chr 2:20,631,640...20,693,777
JBrowse link
G Has2 hyaluronan synthase 2 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of HAS2 mRNA CTD PMID:19059307 NCBI chr 7:88,113,326...88,139,337
Ensembl chr 7:88,113,326...88,128,933
JBrowse link
G Hba-a1 hemoglobin alpha, adult chain 1 affects expression EXP Raloxifene Hydrochloride affects the expression of HBA-A1 mRNA CTD PMID:16079270 NCBI chr10:15,337,265...15,338,121
Ensembl chr10:15,307,815...15,338,392
JBrowse link
G Hbegf heparin-binding EGF-like growth factor multiple interactions
decreases expression
ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of HBEGF mRNA; [Raloxifene Hydrochloride co-treated with PX-866] results in decreased expression of HBEGF mRNA
Raloxifene Hydrochloride results in decreased expression of HBEGF mRNA
CTD PMID:19059307 PMID:27017931 NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441
JBrowse link
G Hbg1 hemoglobin subunit gamma 1 affects expression EXP Raloxifene Hydrochloride affects the expression of HBG1 mRNA CTD PMID:16079270 NCBI chr 1:158,271,871...158,273,426
Ensembl chr 1:158,271,873...158,273,425
JBrowse link
G Hbp1 HMG-box transcription factor 1 increases expression ISO Raloxifene Hydrochloride results in increased expression of HBP1 mRNA CTD PMID:16497877 NCBI chr 6:48,529,633...48,555,775
Ensembl chr 6:48,529,372...48,555,787
JBrowse link
G Heg1 heart development protein with EGF-like domains 1 affects expression
multiple interactions
ISO Raloxifene Hydrochloride affects the expression of HEG1 mRNA
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of HEG1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HEG1 mRNA
CTD PMID:14699072 PMID:19059307 NCBI chr11:67,006,954...67,095,020
Ensembl chr11:66,957,190...67,095,051
JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 increases expression ISO Raloxifene Hydrochloride results in increased expression of HERPUD1 mRNA CTD PMID:16497877 NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424
JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 multiple interactions ISO Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of HEY2 mRNA] CTD PMID:21185374 NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218
JBrowse link
G Hgf hepatocyte growth factor decreases expression ISO Raloxifene Hydrochloride results in decreased expression of HGF mRNA CTD PMID:16497877 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
JBrowse link
G Hk1 hexokinase 1 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of HK1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HK1 mRNA CTD PMID:19059307 NCBI chr20:30,230,488...30,332,099
Ensembl chr20:30,230,486...30,332,131
JBrowse link
G Hmcn1 hemicentin 1 multiple interactions ISO [Raloxifene Hydrochloride co-treated with Estradiol] results in increased expression of HMCN1 mRNA CTD PMID:21185374 NCBI chr13:62,615,461...63,084,524
Ensembl chr13:62,615,461...63,084,524
JBrowse link
G Hmga2 high mobility group AT-hook 2 affects expression ISO Raloxifene Hydrochloride affects the expression of HMGA2 mRNA CTD PMID:14699072 NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784
JBrowse link
G Hmgb1 high mobility group box 1 decreases expression
affects expression
ISO
EXP
Raloxifene Hydrochloride results in decreased expression of HMGB1 mRNA
Raloxifene Hydrochloride affects the expression of HMGB1 mRNA
CTD PMID:16079270 PMID:16514628 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
decreases expression
affects expression
ISO
EXP
1,10-phenanthroline inhibits the reaction [Raloxifene Hydrochloride results in increased expression of HMOX1 mRNA]; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HMOX1 mRNA; Allopurinol inhibits the reaction [Raloxifene Hydrochloride results in increased expression of HMOX1 mRNA]; Buthionine Sulfoximine promotes the reaction [Raloxifene Hydrochloride results in increased expression of HMOX1 mRNA]; Copper promotes the reaction [Raloxifene Hydrochloride results in increased expression of HMOX1 mRNA]; dimethyl sulfate inhibits the reaction [Raloxifene Hydrochloride results in increased expression of HMOX1 mRNA]; Glutathione inhibits the reaction [Raloxifene Hydrochloride results in increased expression of HMOX1 mRNA]; HMOX1 protein promotes the reaction [[Raloxifene Hydrochloride results in decreased expression of NOS2 protein] which results in decreased chemical synthesis of Nitric Oxide]; Iron promotes the reaction [Raloxifene Hydrochloride results in increased expression of HMOX1 mRNA]; MAP2K6 protein promotes the reaction [Raloxifene Hydrochloride results in increased expression of HMOX1 protein]; TEMPO inhibits the reaction [Raloxifene Hydrochloride results in increased expression of HMOX1 mRNA]
Raloxifene Hydrochloride results in increased expression of HMOX1 mRNA; Raloxifene Hydrochloride results in increased expression of HMOX1 protein
Raloxifene Hydrochloride results in decreased expression of HMOX1 mRNA
Raloxifene Hydrochloride affects the expression of HMOX1 mRNA
CTD PMID:16079270 PMID:16298037 PMID:19059307 PMID:20888885 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha decreases expression
multiple interactions
ISO Raloxifene Hydrochloride results in decreased expression of HNF4A mRNA
fulvestrant inhibits the reaction [Raloxifene Hydrochloride results in decreased expression of HNF4A mRNA]
CTD PMID:23184660 NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320
JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 decreases expression ISO Raloxifene Hydrochloride results in decreased expression of HNRNPA2B1 mRNA CTD PMID:16514628 NCBI chr 4:80,534,659...80,545,297
Ensembl chr 4:80,534,651...80,545,249
JBrowse link
G Hnrnph1 heterogeneous nuclear ribonucleoprotein H1 decreases expression ISO Raloxifene Hydrochloride results in decreased expression of HNRNPH1 mRNA CTD PMID:16514628 NCBI chr10:34,692,868...34,702,849
Ensembl chr10:34,693,555...34,702,846
JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U decreases expression ISO Raloxifene Hydrochloride results in decreased expression of HNRNPU mRNA CTD PMID:16514628 NCBI chr13:90,069,058...90,086,905
Ensembl chr13:90,074,181...90,086,588
JBrowse link
G Homer2 homer scaffold protein 2 affects expression ISO Raloxifene Hydrochloride affects the expression of HOMER2 mRNA CTD PMID:14699072 NCBI chr 1:135,558,977...135,659,780
Ensembl chr 1:135,567,414...135,659,772
JBrowse link
G Hoxa1 homeobox A1 affects expression EXP Raloxifene Hydrochloride affects the expression of HOXA1 mRNA CTD PMID:16079270 NCBI chr 4:81,255,814...81,258,587
Ensembl chr 4:81,255,883...81,258,504
JBrowse link
G Hpcal1 hippocalcin-like 1 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HPCAL1 mRNA CTD PMID:19059307 NCBI chr 6:40,478,206...40,584,721
Ensembl chr 6:40,478,208...40,584,687
JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase multiple interactions ISO Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of HPGD mRNA] CTD PMID:21185374 NCBI chr16:33,986,265...34,024,228
Ensembl chr16:33,986,266...34,024,228
JBrowse link
G Hsd17b11 hydroxysteroid (17-beta) dehydrogenase 11 multiple interactions ISO [Raloxifene Hydrochloride co-treated with Estradiol] results in increased expression of HSD17B11 mRNA CTD PMID:21185374 NCBI chr14:5,693,304...5,743,157
Ensembl chr14:5,711,964...5,743,161
JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 affects expression EXP Raloxifene Hydrochloride affects the expression of HSD17B4 mRNA CTD PMID:16079270 NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 decreases expression ISO Raloxifene Hydrochloride results in decreased expression of HSP90AB1 mRNA CTD PMID:16514628 NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488
JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 decreases expression ISO Raloxifene Hydrochloride results in decreased expression of HSP90B1 mRNA CTD PMID:16514628 NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A affects expression
increases expression
ISO
EXP
Raloxifene Hydrochloride affects the expression of HSPA1A mRNA
Raloxifene Hydrochloride results in increased expression of HSPA1A protein
CTD PMID:14699072 PMID:15860553 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B multiple interactions
affects expression
ISO ESR1 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of HSPA1B mRNA]
Raloxifene Hydrochloride affects the expression of HSPA1B mRNA
CTD PMID:14699072 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240
JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 decreases expression ISO Raloxifene Hydrochloride results in decreased expression of HSPA4 mRNA CTD PMID:16514628 NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 decreases expression ISO Raloxifene Hydrochloride results in decreased expression of HSPA8 mRNA CTD PMID:16514628 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
JBrowse link
G Hspb8 heat shock protein family B (small) member 8 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HSPB8 mRNA; Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of HSPB8 mRNA] CTD PMID:19059307 PMID:21185374 NCBI chr12:40,176,405...40,205,002
Ensembl chr12:40,176,532...40,191,185
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 decreases expression
affects expression
ISO
EXP
Raloxifene Hydrochloride results in decreased expression of HSPD1 mRNA
Raloxifene Hydrochloride affects the expression of HSPD1 mRNA
CTD PMID:16079270 PMID:16514628 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A affects expression
multiple interactions
ISO
EXP
Raloxifene Hydrochloride affects the expression of HTR2A mRNA
Raloxifene Hydrochloride inhibits the reaction [estradiol 3-benzoate results in increased expression of HTR2A mRNA]; Raloxifene Hydrochloride inhibits the reaction [estradiol 3-benzoate results in increased expression of HTR2A protein]
CTD PMID:14699072 PMID:17398000 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928
JBrowse link
G Htr3a 5-hydroxytryptamine receptor 3A multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HTR3A mRNA CTD PMID:19059307 NCBI chr 8:49,242,018...49,254,475
Ensembl chr 8:49,242,020...49,254,389
JBrowse link
G Htr5a 5-hydroxytryptamine receptor 5A affects expression EXP Raloxifene Hydrochloride affects the expression of HTR5A mRNA CTD PMID:16079270 NCBI chr 4:7,444,968...7,454,651
Ensembl chr 4:7,444,968...7,454,651
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO Raloxifene Hydrochloride affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of ICAM1 protein] CTD PMID:32828944 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Id1 inhibitor of DNA binding 1 affects expression ISO Raloxifene Hydrochloride affects the expression of ID1 mRNA CTD PMID:14699072 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
JBrowse link
G Id4 inhibitor of DNA binding 4 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ID4 mRNA CTD PMID:19059307 NCBI chr17:16,389,387...16,391,956
Ensembl chr17:16,389,387...16,392,470
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 multiple interactions
affects expression
ISO
EXP
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of IDH2 mRNA; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of IDH2 mRNA]
Raloxifene Hydrochloride affects the expression of IDH2 mRNA
CTD PMID:14699072 PMID:16079270 PMID:19059307 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 multiple interactions
increases expression
ISO Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of IDO1 mRNA]
Raloxifene Hydrochloride results in increased expression of IDO1 mRNA
CTD PMID:18367319 NCBI chr16:67,430,654...67,442,726
Ensembl chr16:67,430,578...67,442,730
JBrowse link
G Ier3 immediate early response 3 affects expression
multiple interactions
ISO Raloxifene Hydrochloride affects the expression of IER3 mRNA
ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of IER3 mRNA]
CTD PMID:14699072 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583
JBrowse link
G Ifit2 interferon-induced protein with tetratricopeptide repeats 2 affects expression ISO Raloxifene Hydrochloride affects the expression of IFIT2 mRNA CTD PMID:14699072 NCBI chr 1:232,102,570...232,108,638
Ensembl chr 1:232,102,570...232,108,635
JBrowse link
G Ifngr2 interferon gamma receptor 2 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of IFNGR2 mRNA CTD PMID:19059307 NCBI chr11:30,779,733...30,798,005
Ensembl chr11:30,779,733...30,798,005
JBrowse link
G Ifrd1 interferon-related developmental regulator 1 decreases expression ISO Raloxifene Hydrochloride results in decreased expression of IFRD1 mRNA CTD PMID:16514628 NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions
decreases expression
increases expression
affects expression
ISO
EXP
Raloxifene Hydrochloride inhibits the reaction [NCOR2 protein binds to IGF1 promoter]; Raloxifene Hydrochloride promotes the reaction [CREBBP protein binds to IGF1 promoter]; Raloxifene Hydrochloride promotes the reaction [ESR1 protein binds to IGF1 promoter]; Raloxifene Hydrochloride promotes the reaction [ESR2 protein binds to IGF1 promoter]; Raloxifene Hydrochloride promotes the reaction [NCOA1 protein binds to IGF1 promoter]; Raloxifene Hydrochloride promotes the reaction [NCOA2 protein binds to IGF1 promoter]; Raloxifene Hydrochloride promotes the reaction [NCOA3 protein binds to IGF1 promoter]
Raloxifene Hydrochloride results in decreased expression of IGF1 mRNA; Raloxifene Hydrochloride results in decreased expression of IGF1 protein
Raloxifene Hydrochloride results in increased expression of IGF1 mRNA
Raloxifene Hydrochloride affects the expression of IGF1 mRNA
CTD PMID:15762036 PMID:15978972 PMID:16912660 PMID:17645796 PMID:17872375 More... NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igf2 insulin-like growth factor 2 increases expression EXP Raloxifene Hydrochloride results in increased expression of IGF2 mRNA CTD PMID:15576828 NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 increases expression ISO Raloxifene Hydrochloride results in increased expression of IGFBP3 protein CTD PMID:15855258 PMID:16912660 NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083
JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 affects expression ISO Raloxifene Hydrochloride affects the expression of IGFBP4 mRNA CTD PMID:14699072 NCBI chr10:83,995,253...84,007,272
Ensembl chr10:83,989,591...84,007,225
JBrowse link
G Igfbp6 insulin-like growth factor binding protein 6 increases expression EXP Raloxifene Hydrochloride results in increased expression of IGFBP6 mRNA CTD PMID:15576828 NCBI chr 7:133,276,309...133,280,944
Ensembl chr 7:133,276,234...133,280,966
JBrowse link
G Il10ra interleukin 10 receptor subunit alpha increases expression ISO Raloxifene Hydrochloride results in increased expression of IL10RA mRNA CTD PMID:16497877 NCBI chr 8:45,563,009...45,578,041
Ensembl chr 8:45,563,137...45,578,061
JBrowse link
G Il11 interleukin 11 multiple interactions ISO [Raloxifene Hydrochloride co-treated with PX-866] results in decreased expression of IL11 mRNA CTD PMID:26660119 NCBI chr 1:69,069,829...69,076,129
Ensembl chr 1:69,068,137...69,076,129
JBrowse link
G Il12a interleukin 12A decreases expression ISO Raloxifene Hydrochloride results in decreased expression of IL12A mRNA CTD PMID:19429434 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
JBrowse link
G Il13ra1 interleukin 13 receptor subunit alpha 1 increases expression ISO Raloxifene Hydrochloride results in increased expression of IL13RA1 mRNA CTD PMID:22217510 NCBI chr  X:115,348,822...115,408,682
Ensembl chr  X:115,348,860...115,408,681
Ensembl chr11:115,348,860...115,408,681
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO
EXP
[Raloxifene Hydrochloride co-treated with IL1B protein] results in increased expression of PTGDS mRNA; Fulvestrant inhibits the reaction [Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased expression of CCL20 protein]]; Fulvestrant inhibits the reaction [Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased phosphorylation of and affects the localization of RELA protein]]; Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased expression of BCL3 mRNA]; Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased expression of CCL20 protein]; Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased expression of CISH mRNA]; Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased expression of CXCL5 mRNA]; Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased expression of PLK3 mRNA]; Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased phosphorylation of and affects the localization of RELA protein]
Fulvestrant inhibits the reaction [Raloxifene Hydrochloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of IL1B mRNA]]; Raloxifene Hydrochloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of IL1B mRNA]; Raloxifene Hydrochloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased secretion of IL1B protein]
CTD PMID:12072388 PMID:24722370 PMID:25305410 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1r1 interleukin 1 receptor type 1 multiple interactions ISO Raloxifene Hydrochloride inhibits the reaction [Estradiol results in decreased expression of IL1R1 mRNA] CTD PMID:21185374 NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937
JBrowse link
G Il1rap interleukin 1 receptor accessory protein affects expression ISO Raloxifene Hydrochloride affects the expression of IL1RAP mRNA CTD PMID:14699072 NCBI chr11:74,062,999...74,199,530
Ensembl chr11:74,070,304...74,199,530
JBrowse link
G Il4 interleukin 4 multiple interactions ISO
EXP
Raloxifene Hydrochloride inhibits the reaction [IL4 protein results in increased phosphorylation of STAT3 protein]
[Raloxifene Hydrochloride co-treated with Bexarotene] affects the reaction [Azoxymethane affects the expression of IL4 mRNA]
CTD PMID:24080207 PMID:24456369 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il4r interleukin 4 receptor affects expression ISO Raloxifene Hydrochloride affects the expression of IL4R mRNA CTD PMID:14699072 NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980
JBrowse link
G Il6 interleukin 6 decreases expression
multiple interactions
decreases secretion
ISO
EXP
Raloxifene Hydrochloride results in decreased expression of IL6 mRNA; Raloxifene Hydrochloride results in decreased expression of IL6 protein
Raloxifene Hydrochloride affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of IL6 protein]; Raloxifene Hydrochloride affects the reaction [[APOE protein affects the susceptibility to IL6 protein] which affects the phosphorylation of STAT3 protein]; Raloxifene Hydrochloride inhibits the reaction [IL6 protein results in increased phosphorylation of and affects the localization of STAT3 protein]; Raloxifene Hydrochloride inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]; Raloxifene Hydrochloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of IL6 mRNA]; Raloxifene Hydrochloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of IL6 protein]; Raloxifene Hydrochloride inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 mRNA]; Raloxifene Hydrochloride inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
Raloxifene Hydrochloride inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]; Raloxifene Hydrochloride inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
ESR1 protein affects the reaction [Raloxifene Hydrochloride results in decreased secretion of IL6 protein]; Raloxifene Hydrochloride inhibits the reaction [[IL6R protein co-treated with IL6 protein] results in increased phosphorylation of STAT3 protein]; Raloxifene Hydrochloride inhibits the reaction [IL6 protein results in increased phosphorylation of and affects the localization of STAT3 protein]; Raloxifene Hydrochloride inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]; Raloxifene Hydrochloride inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
CTD PMID:15579764 PMID:15762036 PMID:15953991 PMID:16298037 PMID:19533603 More... NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Il6r interleukin 6 receptor multiple interactions ISO Raloxifene Hydrochloride inhibits the reaction [[IL6R protein co-treated with IL6 protein] results in increased phosphorylation of STAT3 protein] CTD PMID:32828944 NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536
JBrowse link
G Il6st interleukin 6 cytokine family signal transducer affects binding ISO Raloxifene Hydrochloride binds to IL6ST protein CTD PMID:24456369 PMID:32940862 NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936
JBrowse link
G Il7r interleukin 7 receptor affects expression ISO Raloxifene Hydrochloride affects the expression of IL7R mRNA CTD PMID:14699072 NCBI chr 2:58,452,393...58,477,757
Ensembl chr 2:58,454,217...58,477,757
JBrowse link
G Ilrun inflammation and lipid regulator with UBA-like and NBR1-like domains decreases expression ISO Raloxifene Hydrochloride results in decreased expression of ILRUN mRNA CTD PMID:16514628 NCBI chr20:5,809,931...5,876,197
Ensembl chr20:5,809,936...5,876,012
JBrowse link
G Inhba inhibin subunit beta A multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of INHBA mRNA CTD PMID:19059307 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982
JBrowse link
G Inpp4b inositol polyphosphate-4-phosphatase type II B affects expression ISO Raloxifene Hydrochloride affects the expression of INPP4B mRNA CTD PMID:14699072 NCBI chr19:25,920,189...26,670,085
Ensembl chr19:25,925,358...26,280,634
JBrowse link
G Inpp5a inositol polyphosphate-5-phosphatase A multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of INPP5A mRNA CTD PMID:19059307 NCBI chr 1:194,190,086...194,380,429
Ensembl chr 1:194,190,393...194,380,428
JBrowse link
G Ins1 insulin 1 multiple interactions ISO IWR-1 compound inhibits the reaction [Raloxifene Hydrochloride inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CTNNB1 protein]]; IWR-1 compound inhibits the reaction [Raloxifene Hydrochloride inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CEBPA protein]]; IWR-1 compound inhibits the reaction [Raloxifene Hydrochloride inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of PPARG protein]]; Raloxifene Hydrochloride affects the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of FABP4 protein]; Raloxifene Hydrochloride inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CTNNB1 protein]; Raloxifene Hydrochloride inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CEBPA protein]; Raloxifene Hydrochloride inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of PPARG protein] CTD PMID:31470850 NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
JBrowse link
G Insig1 insulin induced gene 1 increases expression ISO Raloxifene Hydrochloride results in increased expression of INSIG1 mRNA CTD PMID:16497877 NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 decreases expression ISO Raloxifene Hydrochloride results in decreased expression of IQGAP1 mRNA CTD PMID:16514628 NCBI chr 1:134,679,581...134,769,776
Ensembl chr 1:134,679,586...134,769,755
JBrowse link
G Irf7 interferon regulatory factor 7 affects expression EXP Raloxifene Hydrochloride affects the expression of IRF7 mRNA CTD PMID:16079270 NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832
JBrowse link
G Isg20 interferon stimulated exonuclease gene 20 multiple interactions
affects expression
ISO [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of ISG20 mRNA
Raloxifene Hydrochloride affects the expression of ISG20 mRNA
CTD PMID:14699072 PMID:19059307 NCBI chr 1:132,829,303...132,837,027
Ensembl chr 1:132,815,123...132,837,027
JBrowse link
G Itgb1 integrin subunit beta 1 increases expression ISO Raloxifene Hydrochloride results in increased expression of ITGB1 mRNA CTD PMID:12154049 PMID:19429434 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
JBrowse link
G Itgb3 integrin subunit beta 3 increases expression ISO Raloxifene Hydrochloride results in increased expression of ITGB3 mRNA CTD PMID:26603317 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
JBrowse link
G Itpr3 inositol 1,4,5-trisphosphate receptor, type 3 affects expression ISO Raloxifene Hydrochloride affects the expression of ITPR3 mRNA CTD PMID:14699072 NCBI chr20:5,136,968...5,202,339
Ensembl chr20:5,136,441...5,202,337
JBrowse link
G Ivl involucrin affects expression
multiple interactions
ISO Raloxifene Hydrochloride affects the expression of IVL mRNA
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of IVL mRNA
CTD PMID:14699072 PMID:19059307 NCBI chr 2:178,146,694...178,160,807
Ensembl chr 2:178,147,061...178,149,100
JBrowse link
G Jag1 jagged canonical Notch ligand 1 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of JAG1 mRNA CTD PMID:19059307 NCBI chr 3:124,406,783...124,442,220
Ensembl chr 3:124,406,794...124,442,209
JBrowse link
G Jak2 Janus kinase 2 multiple interactions
decreases expression
ISO Raloxifene Hydrochloride promotes the reaction [GH1 protein results in increased phosphorylation of JAK2 protein]
Raloxifene Hydrochloride results in decreased expression of JAK2 mRNA
CTD PMID:17272397 PMID:26865669 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression ISO Raloxifene Hydrochloride results in increased expression of JUN mRNA CTD PMID:12154049 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Kazn kazrin, periplakin interacting protein multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of KAZN mRNA CTD PMID:19059307 NCBI chr 5:154,392,793...155,381,567
Ensembl chr 5:154,392,793...154,779,074
JBrowse link
G Kcnd3 potassium voltage-gated channel subfamily D member 3 multiple interactions
decreases activity
decreases expression
EXP
ISO
Raloxifene Hydrochloride promotes the reaction [Fulvestrant results in decreased activity of KCND3 protein]
Raloxifene Hydrochloride results in decreased activity of KCND3 protein
[KCNIP2 protein co-treated with Raloxifene Hydrochloride] results in decreased activity of KCND3 protein
Raloxifene Hydrochloride results in decreased expression of KCND3 mRNA
CTD PMID:25231973 NCBI chr 2:192,937,950...193,155,345
Ensembl chr 2:192,937,950...193,155,345
JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 increases expression EXP Raloxifene Hydrochloride results in increased expression of KCNE1 mRNA CTD PMID:15576828 NCBI chr11:31,580,951...31,594,116
Ensembl chr11:31,580,742...31,593,901
JBrowse link
G Kcnh5 potassium voltage-gated channel subfamily H member 5 affects expression EXP Raloxifene Hydrochloride affects the expression of KCNH5 mRNA CTD PMID:16079270 NCBI chr 6:93,615,174...93,908,107
Ensembl chr 6:93,624,529...93,908,107
JBrowse link
G Kcnip2 potassium voltage-gated channel interacting protein 2 multiple interactions ISO [KCNIP2 protein co-treated with Raloxifene Hydrochloride] results in decreased activity of KCND3 protein CTD PMID:25231973 NCBI chr 1:244,641,147...244,664,939
Ensembl chr 1:244,641,150...244,664,874
JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 multiple interactions
affects expression
ISO [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of KCNN4 mRNA
Raloxifene Hydrochloride affects the expression of KCNN4 mRNA
CTD PMID:14699072 PMID:19059307 NCBI chr 1:79,956,380...79,974,354
Ensembl chr 1:79,959,322...79,974,340
JBrowse link
G Kctd12 potassium channel tetramerization domain containing 12 multiple interactions
affects expression
ISO [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of KCTD12 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of KCTD12 mRNA
Raloxifene Hydrochloride affects the expression of KCTD12 mRNA
CTD PMID:14699072 PMID:19059307 NCBI chr15:79,800,078...79,806,017
Ensembl chr15:79,801,191...79,806,282
JBrowse link
G Kif20a kinesin family member 20A decreases expression ISO Raloxifene Hydrochloride results in decreased expression of KIF20A mRNA CTD PMID:16514628 NCBI chr18:26,230,294...26,238,780
Ensembl chr18:26,230,230...26,238,780
JBrowse link
G Kif3c kinesin family member 3C multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of KIF3C mRNA CTD PMID:19059307 NCBI chr 6:26,367,092...26,406,033
Ensembl chr 6:26,366,531...26,406,130
JBrowse link
G Kiss1 KiSS-1 metastasis-suppressor decreases expression EXP Raloxifene Hydrochloride results in decreased expression of KISS1 mRNA CTD PMID:27395752 NCBI chr13:44,775,106...44,780,707
Ensembl chr13:44,774,823...44,780,612
JBrowse link
G Klf10 KLF transcription factor 10 affects expression ISO Raloxifene Hydrochloride affects the expression of KLF10 mRNA CTD PMID:14699072 NCBI chr 7:69,467,658...69,473,726
Ensembl chr 7:69,465,619...69,473,994
JBrowse link
G Klf6 KLF transcription factor 6 decreases expression EXP Raloxifene Hydrochloride results in decreased expression of KLF6 mRNA CTD PMID:15576828 NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570
JBrowse link
G Klhl24 kelch-like family member 24 increases expression ISO Raloxifene Hydrochloride results in increased expression of KLHL24 mRNA CTD PMID:19429434 NCBI chr11:80,843,621...80,877,649
Ensembl chr11:80,846,755...80,877,636
JBrowse link
G Klrc1 killer cell lectin like receptor C1 increases expression ISO Raloxifene Hydrochloride results in increased expression of KLRC1 mRNA CTD PMID:17962382 NCBI chr 4:163,142,142...163,152,425
Ensembl chr 4:163,147,189...163,152,425
JBrowse link
G Klrc2 killer cell lectin like receptor C2 affects expression
multiple interactions
ISO Raloxifene Hydrochloride affects the expression of KLRC2 mRNA
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of KLRC2 mRNA; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of KLRC2 mRNA]; ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of KLRC2 mRNA]
CTD PMID:14699072 PMID:19059307 NCBI chr 4:163,122,700...163,133,843
Ensembl chr 4:163,122,704...163,133,843
JBrowse link
G Klrc3 killer cell lectin like receptor C3 multiple interactions
increases expression
ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of KLRC3 mRNA; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of KLRC3 mRNA]; Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of KLRC3 mRNA]; Raloxifene Hydrochloride promotes the reaction [ESR1 protein binds to KLRC3 gene]; Raloxifene Hydrochloride promotes the reaction [NCOA3 protein binds to KLRC3 gene] CTD PMID:17395694 PMID:19059307 NCBI chr 4:163,105,081...163,112,737
Ensembl chr 4:163,106,024...163,112,336
JBrowse link
G Klrk1 killer cell lectin like receptor K1 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of KLRK1 mRNA CTD PMID:19059307 NCBI chr 4:163,079,887...163,092,434
Ensembl chr 4:163,081,927...163,092,459
JBrowse link
G Kpna2 karyopherin subunit alpha 2 decreases expression ISO Raloxifene Hydrochloride results in decreased expression of KPNA2 mRNA CTD PMID:16514628 NCBI chr10:91,933,951...91,946,115
Ensembl chr10:91,933,951...91,946,150
JBrowse link
G Kpnb1 karyopherin subunit beta 1 decreases expression ISO Raloxifene Hydrochloride results in decreased expression of KPNB1 mRNA CTD PMID:16514628 NCBI chr10:82,145,662...82,174,437
Ensembl chr10:82,145,420...82,174,605
JBrowse link
G Krt17 keratin 17 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of KRT17 mRNA CTD PMID:19059307 NCBI chr10:85,178,673...85,183,392
Ensembl chr10:85,178,675...85,183,392
JBrowse link
G Krt34 keratin 34 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of KRT34 mRNA CTD PMID:19059307 NCBI chr10:84,969,988...84,974,098
Ensembl chr10:84,970,017...84,974,040
JBrowse link
G L3mbtl1 L3MBTL histone methyl-lysine binding protein 1 decreases expression ISO Raloxifene Hydrochloride results in decreased expression of L3MBTL1 mRNA CTD PMID:19429434 NCBI chr 3:151,597,903...151,633,657
Ensembl chr 3:151,602,980...151,631,233
JBrowse link
G Lamb1 laminin subunit beta 1 multiple interactions ISO [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of LAMB1 mRNA CTD PMID:24431404 NCBI chr 6:47,835,492...47,902,585
Ensembl chr 6:47,835,525...47,902,585
JBrowse link
G Lamc1 laminin subunit gamma 1 affects expression ISO Raloxifene Hydrochloride affects the expression of LAMC1 mRNA CTD PMID:14699072 NCBI chr13:65,374,372...65,501,492
Ensembl chr13:65,374,372...65,501,492
JBrowse link
G Lbh LBH regulator of WNT signaling pathway multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of LBH mRNA CTD PMID:19059307 NCBI chr 6:22,569,238...22,593,056
Ensembl chr 6:22,568,834...22,593,079
JBrowse link
G Lcn2 lipocalin 2 affects expression ISO Raloxifene Hydrochloride affects the expression of LCN2 mRNA CTD PMID:14699072 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
JBrowse link
G Ldlr low density lipoprotein receptor increases expression ISO Raloxifene Hydrochloride results in increased expression of LDLR mRNA CTD PMID:16497877 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Ldlrad4 low density lipoprotein receptor class A domain containing 4 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of LDLRAD4 mRNA CTD PMID:19059307 NCBI chr18:61,519,253...61,848,403
Ensembl chr18:61,521,428...61,843,238
JBrowse link
G Lepr leptin receptor affects expression EXP Raloxifene decreases Lepr protein expression in adipose tissue at 7 weeks and increases it at 22 weeks RGD PMID:15059958 RGD:1581837 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
G Lgr5 leucine rich repeat containing G protein coupled receptor 5 multiple interactions ISO [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of LGR5 mRNA; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of LGR5 protein CTD PMID:24431404 NCBI chr 7:51,087,059...51,221,882
Ensembl chr 7:51,088,239...51,222,446
JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions
decreases secretion
EXP Raloxifene Hydrochloride inhibits the reaction [estradiol 3-benzoate results in increased secretion of LHB protein]
Raloxifene Hydrochloride results in decreased secretion of LHB protein
CTD PMID:17398000 PMID:27395752 NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972
JBrowse link
G Lif LIF, interleukin 6 family cytokine multiple interactions
decreases expression
ISO [Raloxifene Hydrochloride co-treated with PX-866] results in decreased expression of LIF mRNA
Raloxifene Hydrochloride results in decreased expression of LIF mRNA
CTD PMID:26603317 PMID:27017931 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482
JBrowse link
G Limch1 LIM and calponin homology domains 1 multiple interactions ISO Raloxifene Hydrochloride promotes the reaction [Estradiol results in increased expression of LIMCH1 mRNA] CTD PMID:21185374 NCBI chr14:41,112,579...41,425,001
Ensembl chr14:41,114,803...41,425,191
JBrowse link
G Liph lipase H multiple interactions ISO [Raloxifene Hydrochloride co-treated with Estradiol] results in increased expression of LIPH mRNA CTD PMID:21185374 NCBI chr11:79,032,229...79,081,625
Ensembl chr11:79,033,312...79,081,625
JBrowse link
G Lmcd1 LIM and cysteine-rich domains 1 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of LMCD1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of LMCD1 mRNA CTD PMID:19059307 NCBI chr 4:145,393,153...145,452,049
Ensembl chr 4:145,393,145...145,452,046
JBrowse link
G Lmnb2 lamin B2 affects expression
multiple interactions
ISO Raloxifene Hydrochloride affects the expression of LMNB2 mRNA
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of LMNB2 mRNA
CTD PMID:14699072 PMID:19059307 NCBI chr 7:8,792,628...8,808,665
Ensembl chr 7:8,789,314...8,808,665
JBrowse link
G Lox lysyl oxidase affects expression EXP Raloxifene Hydrochloride affects the expression of LOX mRNA CTD PMID:16079270 NCBI chr18:45,964,544...45,977,431
Ensembl chr18:45,967,343...46,041,477
JBrowse link
G Lpl lipoprotein lipase multiple interactions
increases expression
ISO [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of LPL mRNA
Raloxifene Hydrochloride results in increased expression of LPL mRNA
CTD PMID:16643890 PMID:19059307 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link
G Lrig1 leucine-rich repeats and immunoglobulin-like domains 1 multiple interactions
affects expression
ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of LRIG1 mRNA
Raloxifene Hydrochloride affects the expression of LRIG1 mRNA
CTD PMID:14699072 PMID:19059307 NCBI chr 4:127,130,899...127,230,956
Ensembl chr 4:127,130,898...127,231,513
JBrowse link
G Lrrc20 leucine rich repeat containing 20 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of LRRC20 mRNA CTD PMID:19059307 NCBI chr20:29,422,858...29,528,372
Ensembl chr20:29,422,925...29,528,369
JBrowse link
G Ltb lymphotoxin beta decreases expression ISO Raloxifene Hydrochloride results in decreased expression of LTB mRNA CTD PMID:19429434 NCBI chr20:3,627,536...3,629,381
Ensembl chr20:3,627,537...3,629,381
JBrowse link
G Ltbp1 latent transforming growth factor beta binding protein 1 affects expression ISO Raloxifene Hydrochloride affects the expression of LTBP1 mRNA CTD PMID:14699072 NCBI chr 6:20,029,629...20,425,339
Ensembl chr 6:20,029,629...20,425,349
JBrowse link
G Lum lumican affects expression ISO Raloxifene Hydrochloride affects the expression of LUM mRNA CTD PMID:14699072 NCBI chr 7:32,358,990...32,365,794
Ensembl chr 7:32,358,614...32,365,793
JBrowse link
G Ly6i lymphocyte antigen 6 complex, locus I affects expression EXP Raloxifene Hydrochloride affects the expression of LY6B mRNA CTD PMID:16079270 NCBI chr 7:107,062,320...107,067,743
Ensembl chr 7:107,062,325...107,067,310
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase multiple interactions ISO [Raloxifene Hydrochloride co-treated with Estradiol] results in increased expression of LYN mRNA CTD PMID:21185374 NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868
JBrowse link
G Lysmd4 LysM domain containing 4 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of LYSMD4 mRNA CTD PMID:19059307 NCBI chr 1:120,839,180...120,845,148
Ensembl chr 1:120,839,282...120,845,135
JBrowse link
G Macroh2a1 macroH2A.1 histone affects expression EXP Raloxifene Hydrochloride affects the expression of MACROH2A1 mRNA CTD PMID:16079270 NCBI chr17:8,479,331...8,542,071
Ensembl chr17:8,479,372...8,542,072
JBrowse link
G Maf MAF bZIP transcription factor increases expression ISO Raloxifene Hydrochloride results in increased expression of MAF mRNA CTD PMID:19429434 NCBI chr19:43,353,867...43,713,162
Ensembl chr19:43,360,342...43,712,365
JBrowse link
G Maff MAF bZIP transcription factor F multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MAFF mRNA CTD PMID:19059307 NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851
JBrowse link
G Man2a2 mannosidase, alpha, class 2A, member 2 affects expression ISO Raloxifene Hydrochloride affects the expression of MAN2A2 mRNA CTD PMID:14699072 NCBI chr 1:134,304,714...134,327,611
Ensembl chr 1:134,306,236...134,327,315
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions
increases lipidation
ISO [Raloxifene Hydrochloride co-treated with Oxygen deficiency] results in increased lipidation of MAP1LC3B protein
Raloxifene Hydrochloride results in increased lipidation of MAP1LC3B protein
CTD PMID:33203845 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
Ensembl chr16:49,665,791...49,677,690
JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of MAP2K3 mRNA CTD PMID:19059307 NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492
JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 multiple interactions ISO MAP2K6 protein promotes the reaction [Raloxifene Hydrochloride results in increased expression of HMOX1 protein] CTD PMID:20888885 NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293
JBrowse link
G Map3k11 mitogen-activated protein kinase kinase kinase 11 increases expression ISO Raloxifene Hydrochloride results in increased expression of MAP3K11 mRNA CTD PMID:12154049 NCBI chr 1:202,975,353...202,988,655
Ensembl chr 1:202,975,353...202,988,652
JBrowse link
G Map3k20 mitogen-activated protein kinase kinase kinase 20 decreases expression ISO Raloxifene Hydrochloride results in decreased expression of MAP3K20 mRNA CTD PMID:19429434 NCBI chr 3:57,130,539...57,289,943
Ensembl chr 3:57,130,551...57,289,626
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MAP3K5 mRNA CTD PMID:19059307 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800
JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MAP3K8 mRNA CTD PMID:19059307 NCBI chr17:53,382,908...53,403,216
Ensembl chr17:53,383,131...53,403,216
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
ISO
EXP
U 0126 inhibits the reaction [Raloxifene Hydrochloride results in increased phosphorylation of MAPK1 protein]
4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [Raloxifene Hydrochloride results in increased phosphorylation of MAPK1 protein]; Raloxifene Hydrochloride inhibits the reaction [Methylmercury Compounds results in increased activity of MAPK1 protein]; sotrastaurin inhibits the reaction [Raloxifene Hydrochloride results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [Raloxifene Hydrochloride results in increased phosphorylation of MAPK1 protein]
CTD PMID:15712295 PMID:16798746 PMID:17174166 PMID:20945400 PMID:24782323 More... NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk14 mitogen activated protein kinase 14 affects expression EXP Raloxifene Hydrochloride affects the expression of MAPK14 mRNA CTD PMID:16079270 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
ISO
EXP
4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [Raloxifene Hydrochloride results in increased phosphorylation of MAPK3 protein]; Raloxifene Hydrochloride inhibits the reaction [Methylmercury Compounds results in increased activity of MAPK3 protein]; sotrastaurin inhibits the reaction [Raloxifene Hydrochloride results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [Raloxifene Hydrochloride results in increased phosphorylation of MAPK3 protein] CTD PMID:15712295 PMID:16798746 PMID:17174166 PMID:20945400 PMID:24782323 More... NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MAPKAPK2 mRNA CTD PMID:19059307 NCBI chr13:42,513,762...42,560,061
Ensembl chr13:42,513,762...42,560,457
JBrowse link
G Marcksl1 MARCKS-like 1 affects expression ISO Raloxifene Hydrochloride affects the expression of MARCKSL1 mRNA CTD PMID:14699072 NCBI chr 5:141,851,491...141,853,814
Ensembl chr 5:141,850,110...141,853,817
JBrowse link
G Matr3 matrin 3 decreases expression ISO Raloxifene Hydrochloride results in decreased expression of MATR3 mRNA CTD PMID:16514628 NCBI chr18:27,154,098...27,193,212
Ensembl chr18:27,163,714...27,193,166
JBrowse link
G Mbnl2 muscleblind-like splicing regulator 2 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MBNL2 mRNA CTD PMID:19059307 NCBI chr15:97,385,278...97,542,924
Ensembl chr15:97,385,244...97,542,937
JBrowse link
G Mctp1 multiple C2 and transmembrane domain containing 1 increases expression ISO Raloxifene Hydrochloride results in increased expression of MCTP1 mRNA CTD PMID:19429434 NCBI chr 2:6,071,408...6,761,833
Ensembl chr 2:6,065,808...6,761,833
JBrowse link
G Mdfic MyoD family inhibitor domain containing affects expression
multiple interactions
ISO Raloxifene Hydrochloride affects the expression of MDFIC mRNA
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MDFIC mRNA
CTD PMID:14699072 PMID:19059307 NCBI chr 4:43,972,310...44,052,162
Ensembl chr 4:43,972,507...44,052,161
JBrowse link
G Mdm2 MDM2 proto-oncogene multiple interactions ISO [Raloxifene Hydrochloride co-treated with PX-866] results in decreased phosphorylation of MDM2 protein CTD PMID:27017931 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Mef2a myocyte enhancer factor 2a multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MEF2A mRNA CTD PMID:19059307 NCBI chr 1:120,847,874...120,982,488
Ensembl chr 1:120,850,080...120,981,948
JBrowse link
G Mfap5 microfibril associated protein 5 multiple interactions
affects expression
ISO ESR1 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of MFAP5 mRNA]
Raloxifene Hydrochloride affects the expression of MFAP5 mRNA
CTD PMID:14699072 NCBI chr 4:155,727,925...155,750,458
Ensembl chr 4:155,727,925...155,750,458
JBrowse link
G Mgp matrix Gla protein multiple interactions
decreases expression
ISO Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of MGP mRNA]
Raloxifene Hydrochloride results in decreased expression of MGP mRNA
CTD PMID:16514628 PMID:21185374 NCBI chr 4:169,766,290...169,769,612
Ensembl chr 4:169,766,279...169,769,667
JBrowse link
G Mical2 microtubule associated monooxygenase, calponin and LIM domain containing 2 decreases expression ISO Raloxifene Hydrochloride results in decreased expression of MICAL2 mRNA CTD PMID:26865669 NCBI chr 1:166,345,853...166,530,575
Ensembl chr 1:166,345,859...166,471,719
Ensembl chr 1:166,345,859...166,471,719
JBrowse link
G Mid1 midline 1 multiple interactions ISO Raloxifene Hydrochloride promotes the reaction [Estradiol results in increased expression of MID1 mRNA] CTD PMID:21185374 NCBI chr  X:24,116,674...24,491,205
Ensembl chr  X:24,120,293...24,248,353
JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression ISO Raloxifene Hydrochloride results in decreased expression of MKI67 protein CTD PMID:11535548 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Mmd2 monocyte to macrophage differentiation-associated 2 increases expression ISO Raloxifene Hydrochloride results in increased expression of MMD2 mRNA CTD PMID:22841776 NCBI chr12:11,962,733...12,009,776
Ensembl chr12:11,962,757...12,009,773
JBrowse link
G Mmp12 matrix metallopeptidase 12 affects expression
multiple interactions
ISO Raloxifene Hydrochloride affects the expression of MMP12 mRNA
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MMP12 mRNA
CTD PMID:14699072 PMID:19059307 NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611
JBrowse link
G Mmp13 matrix metallopeptidase 13 multiple interactions EXP Raloxifene Hydrochloride inhibits the reaction [Decitabine results in increased expression of MMP13 mRNA] CTD PMID:23385821 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239
JBrowse link
G Mmp2 matrix metallopeptidase 2 affects expression
multiple interactions
EXP
ISO
Raloxifene Hydrochloride affects the expression of MMP2 mRNA
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Raloxifene Hydrochloride inhibits the reaction [Streptozocin results in decreased secretion of MMP2 protein]]; ESR2 protein affects the reaction [Raloxifene Hydrochloride inhibits the reaction [Streptozocin results in decreased secretion of MMP2 protein]]; Raloxifene Hydrochloride inhibits the reaction [Streptozocin results in decreased expression of MMP2 mRNA]; Raloxifene Hydrochloride inhibits the reaction [Streptozocin results in decreased secretion of MMP2 protein]
CTD PMID:16079270 PMID:23471663 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp3 matrix metallopeptidase 3 multiple interactions EXP Raloxifene Hydrochloride inhibits the reaction [Decitabine results in increased expression of MMP3 mRNA] CTD PMID:23385821 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases activity
decreases expression
increases expression
multiple interactions
ISO
EXP
Raloxifene Hydrochloride results in decreased activity of MMP9 protein
Raloxifene Hydrochloride results in decreased expression of MMP9 mRNA
Raloxifene Hydrochloride results in increased expression of MMP9 mRNA
[9,10-Dimethyl-1,2-benzanthracene co-treated with Raloxifene Hydrochloride co-treated with Fluoxetine] affects the expression of MMP9 protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with Raloxifene Hydrochloride] affects the expression of MMP9 protein
CTD PMID:17582780 PMID:22841776 PMID:31332895 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mn1 MN1 proto-oncogene, transcriptional regulator multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MN1 mRNA CTD PMID:19059307 NCBI chr12:45,181,794...45,220,959
Ensembl chr12:45,183,085...45,221,651
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP Carrageenan inhibits the reaction [Raloxifene Hydrochloride results in increased activity of MPO protein] CTD PMID:15860553 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Mpped2 metallophosphoesterase domain containing 2 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MPPED2 mRNA CTD PMID:19059307 NCBI chr 3:93,180,895...93,355,605
Ensembl chr 3:93,181,167...93,355,618
JBrowse link
G Mr1 major histocompatibility complex, class I-related increases expression ISO Raloxifene Hydrochloride results in increased expression of MR1 mRNA CTD PMID:19429434 NCBI chr13:67,298,362...67,317,985
Ensembl chr13:67,299,585...67,317,970
JBrowse link
G Mrpl33 mitochondrial ribosomal protein L33 affects expression ISO Raloxifene Hydrochloride affects the expression of MRPL33 mRNA CTD PMID:14699072 NCBI chr 6:24,825,800...24,833,994
Ensembl chr 6:24,825,827...24,833,834
JBrowse link
G Msmb microseminoprotein, beta multiple interactions
affects expression
ISO [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of MSMB mRNA; ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of MSMB mRNA]
Raloxifene Hydrochloride affects the expression of MSMB mRNA
CTD PMID:14699072 PMID:19059307 NCBI chr16:7,366,536...7,387,124
Ensembl chr16:7,366,536...7,387,123
JBrowse link
G Mst1 macrophage stimulating 1 increases expression ISO Raloxifene Hydrochloride results in increased expression of MST1 mRNA CTD PMID:19429434 NCBI chr 8:108,767,886...108,773,425
Ensembl chr 8:108,768,839...108,773,416
JBrowse link
G Mt2A metallothionein 2A increases expression ISO Raloxifene Hydrochloride results in increased expression of MT2A mRNA CTD PMID:20945400 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Mthfr methylenetetrahydrofolate reductase decreases expression ISO Raloxifene Hydrochloride results in decreased expression of MTHFR mRNA CTD PMID:15849065 NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797
JBrowse link
G Mtor mechanistic target of rapamycin kinase increases phosphorylation ISO Raloxifene Hydrochloride results in increased phosphorylation of MTOR protein CTD PMID:25537862 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Muc1 mucin 1, cell surface associated increases expression
affects expression
ISO
EXP
Raloxifene Hydrochloride results in increased expression of MUC1 protein
Raloxifene Hydrochloride affects the expression of MUC1 mRNA
CTD PMID:16012748 PMID:16079270 NCBI chr 2:174,635,989...174,640,738
Ensembl chr 2:174,635,995...174,640,733
JBrowse link
G Myb MYB proto-oncogene, transcription factor multiple interactions
decreases expression
ISO Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of MYB mRNA]
Raloxifene Hydrochloride results in decreased expression of MYB mRNA
CTD PMID:21185374 PMID:26865669 NCBI chr 1:15,939,771...15,973,367
Ensembl chr 1:15,939,761...15,973,057
JBrowse link
G Mybl1 MYB proto-oncogene like 1 multiple interactions
decreases expression
ISO [Raloxifene Hydrochloride co-treated with Estradiol] results in decreased expression of MYBL1 mRNA
Raloxifene Hydrochloride results in decreased expression of MYBL1 mRNA
CTD PMID:21185374 PMID:26865669 NCBI chr 5:9,582,905...9,618,179
Ensembl chr 5:9,582,934...9,618,183
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions
decreases expression
increases expression
ISO GPER1 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of MYC mRNA]; Raloxifene Hydrochloride inhibits the reaction [[NRG1 protein co-treated with Estradiol] results in increased expression of MYC protein]
Raloxifene Hydrochloride results in decreased expression of MYC mRNA; Raloxifene Hydrochloride results in decreased expression of MYC protein
CTD PMID:16497877 PMID:20945400 PMID:22453024 PMID:26502914 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Myl9 myosin light chain 9 affects expression EXP Raloxifene Hydrochloride affects the expression of MYL9 mRNA CTD PMID:16079270 NCBI chr 3:145,281,943...145,288,333
Ensembl chr 3:145,281,937...145,288,333
JBrowse link
G Myo10 myosin X affects expression ISO Raloxifene Hydrochloride affects the expression of MYO10 mRNA CTD PMID:14699072 NCBI chr 2:76,100,989...76,305,619
Ensembl chr 2:76,100,987...76,303,030
JBrowse link
G Myod1 myogenic differentiation 1 decreases expression ISO Raloxifene Hydrochloride results in decreased expression of MYOD1 mRNA CTD PMID:19432593 NCBI chr 1:96,884,864...96,887,574
Ensembl chr 1:96,884,948...96,887,554
JBrowse link
G Myt1l myelin transcription factor 1-like multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MYT1L mRNA CTD PMID:19059307 NCBI chr 6:46,164,742...46,564,234
Ensembl chr 6:46,428,150...46,561,671
JBrowse link
G Nab1 Ngfi-A binding protein 1 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of NAB1 mRNA CTD PMID:19059307 NCBI chr 9:49,053,579...49,093,078
Ensembl chr 9:49,053,758...49,092,098
JBrowse link
G Nars1 asparaginyl-tRNA synthetase 1 decreases expression ISO Raloxifene Hydrochloride results in decreased expression of NARS1 mRNA CTD PMID:16514628 NCBI chr18:57,989,308...58,005,584
Ensembl chr18:57,989,308...58,005,622
JBrowse link
G Nav2 neuron navigator 2 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NAV2 mRNA CTD PMID:19059307 NCBI chr 1:98,957,629...99,322,339
Ensembl chr 1:98,663,759...99,322,337
JBrowse link
G Nbl1 NBL1, DAN family BMP antagonist increases expression EXP Raloxifene Hydrochloride results in increased expression of NBL1 mRNA CTD PMID:15576828 NCBI chr 5:151,318,752...151,329,948
Ensembl chr 5:151,318,754...151,338,719
JBrowse link
G Ncaph non-SMC condensin I complex, subunit H decreases expression ISO Raloxifene Hydrochloride results in decreased expression of NCAPH mRNA CTD PMID:16514628 NCBI chr 3:114,371,937...114,399,178
Ensembl chr 3:114,371,941...114,399,180
JBrowse link
G Ncf2 neutrophil cytosolic factor 2 multiple interactions
affects expression
ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NCF2 mRNA; ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of NCF2 mRNA]
Raloxifene Hydrochloride affects the expression of NCF2 mRNA
CTD PMID:14699072 PMID:19059307 NCBI chr13:64,955,622...64,986,144
Ensembl chr13:64,955,503...64,986,277
JBrowse link
G Ncl nucleolin decreases expression ISO Raloxifene Hydrochloride results in decreased expression of NCL mRNA CTD PMID:16514628 NCBI chr 9:86,999,588...87,008,112
Ensembl chr 9:86,998,019...87,008,136
JBrowse link
G Ncoa1 nuclear receptor coactivator 1 multiple interactions
increases expression
ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NCOA1 mRNA; Raloxifene Hydrochloride promotes the reaction [NCOA1 protein binds to IGF1 promoter]
Raloxifene Hydrochloride results in increased expression of NCOA1 mRNA
CTD PMID:17872375 PMID:19059307 PMID:19432593 NCBI chr 6:27,232,609...27,507,992
Ensembl chr 6:27,232,611...27,475,664
JBrowse link
G Ncoa2 nuclear receptor coactivator 2 multiple interactions
increases expression
ISO Raloxifene Hydrochloride promotes the reaction [NCOA2 protein binds to IGF1 promoter]; Raloxifene Hydrochloride promotes the reaction [NCOA2 protein binds to PTGS2 promoter]
Raloxifene Hydrochloride results in increased expression of NCOA2 protein
CTD PMID:16739346 PMID:17872375 NCBI chr 5:5,835,642...6,069,693
Ensembl chr 5:5,835,706...6,067,451
JBrowse link
G Ncoa3 nuclear receptor coactivator 3 multiple interactions ISO Raloxifene Hydrochloride promotes the reaction [NCOA3 protein binds to IGF1 promoter]; Raloxifene Hydrochloride promotes the reaction [NCOA3 protein binds to KLRC3 gene]; Raloxifene Hydrochloride promotes the reaction [NCOA3 protein binds to PTGS2 promoter] CTD PMID:17395694 PMID:17872375 NCBI chr 3:154,738,566...154,821,395
Ensembl chr 3:154,738,581...154,818,594
JBrowse link
G Ncoa4 nuclear receptor coactivator 4 affects expression
multiple interactions
ISO Raloxifene Hydrochloride affects the expression of NCOA4 mRNA
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NCOA4 mRNA
CTD PMID:14699072 PMID:19059307 NCBI chr16:7,389,222...7,409,564
Ensembl chr16:7,366,542...7,409,641
Ensembl chr16:7,366,542...7,409,641
JBrowse link
G Ncor2 nuclear receptor co-repressor 2 multiple interactions
decreases expression
ISO Raloxifene Hydrochloride inhibits the reaction [NCOR2 protein binds to IGF1 promoter]; Raloxifene Hydrochloride inhibits the reaction [NCOR2 protein binds to PTGS2 promoter]
Raloxifene Hydrochloride results in decreased expression of NCOR2 mRNA
CTD PMID:17872375 PMID:19432593 NCBI chr12:31,466,418...31,628,319
Ensembl chr12:31,466,412...31,628,319
JBrowse link
G Ndrg4 NDRG family member 4 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NDRG4 mRNA CTD PMID:19059307 NCBI chr19:9,351,408...9,387,398
Ensembl chr19:9,351,404...9,386,914
JBrowse link
G Ndufa2 NADH:ubiquinone oxidoreductase subunit A2 affects expression ISO Raloxifene Hydrochloride affects the expression of NDUFA2 mRNA CTD PMID:14699072 NCBI chr18:28,355,774...28,357,863
Ensembl chr18:28,355,774...28,358,076
JBrowse link
G Nectin1 nectin cell adhesion molecule 1 affects expression EXP Raloxifene Hydrochloride affects the expression of NECTIN1 mRNA CTD PMID:16079270 NCBI chr 8:44,101,776...44,164,863
Ensembl chr 8:44,101,776...44,189,787
JBrowse link
G Nefl neurofilament light chain affects expression ISO Raloxifene Hydrochloride affects the expression of NEFL mRNA CTD PMID:14699072 NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793
JBrowse link
G Nek7 NIMA-related kinase 7 affects expression ISO Raloxifene Hydrochloride affects the expression of NEK7 mRNA CTD PMID:14699072 NCBI chr13:50,022,212...50,149,374
Ensembl chr13:50,022,218...50,149,296
JBrowse link
G Nf1 neurofibromin 1 increases expression ISO Raloxifene Hydrochloride results in increased expression of NF1 mRNA CTD PMID:19429434 NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658
JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NFATC1 mRNA CTD PMID:19059307 NCBI chr18:74,046,422...74,156,041
Ensembl chr18:74,046,904...74,156,028
JBrowse link
G Nfe2l1 NFE2 like bZIP transcription factor 1 increases expression ISO Raloxifene Hydrochloride results in increased expression of NFE2L1 mRNA CTD PMID:16497877 NCBI chr10:81,796,055...81,812,926
Ensembl chr10:81,800,366...81,832,318
JBrowse link
G Nfil3 nuclear factor, interleukin 3 regulated affects expression
multiple interactions
ISO Raloxifene Hydrochloride affects the expression of NFIL3 mRNA
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NFIL3 mRNA
CTD PMID:14699072 PMID:19059307 NCBI chr17:12,280,499...12,295,728
Ensembl chr17:12,280,484...12,295,858
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions EXP Raloxifene Hydrochloride promotes the reaction [NFKB1 protein binds to SLC1A2 promoter] CTD PMID:24782323 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
decreases expression
affects expression
ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NFKBIA mRNA
Raloxifene Hydrochloride results in decreased expression of NFKBIA mRNA
Raloxifene Hydrochloride affects the expression of NFKBIA mRNA
Raloxifene Hydrochloride inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]; SFRP5 protein affects the reaction [Raloxifene Hydrochloride inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]]
CTD PMID:14699072 PMID:16298037 PMID:19059307 PMID:31470850 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nfkbie NFKB inhibitor epsilon multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of NFKBIE mRNA CTD PMID:19059307 NCBI chr 9:15,443,600...15,450,437
Ensembl chr 9:15,436,941...15,450,437
JBrowse link
G Nherf1 NHERF family PDZ scaffold protein 1 affects expression ISO Raloxifene Hydrochloride affects the expression of NHERF1 mRNA CTD PMID:14699072 NCBI chr10:100,403,189...100,420,290
Ensembl chr10:100,403,069...100,420,598
JBrowse link
G Ninj1 ninjurin 1 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NINJ1 mRNA CTD PMID:19059307 NCBI chr17:15,452,804...15,461,684
Ensembl chr17:15,452,813...15,461,704
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of NLRP3 mRNA CTD PMID:19059307 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
JBrowse link
G Nme6 NME/NM23 nucleoside diphosphate kinase 6 affects expression EXP Raloxifene Hydrochloride affects the expression of NME6 mRNA CTD PMID:16079270 NCBI chr 8:109,832,085...109,839,301
Ensembl chr 8:109,832,589...109,839,301
JBrowse link
G Nmrk1 nicotinamide riboside kinase 1 decreases expression ISO Raloxifene Hydrochloride results in decreased expression of NMRK1 mRNA CTD PMID:26865669 NCBI chr 1:216,049,350...216,076,792
Ensembl chr 1:216,049,437...216,076,791
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
decreases expression
ISO
EXP
[Raloxifene Hydrochloride co-treated with 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid] results in increased expression of NOS2 protein; [Raloxifene Hydrochloride results in decreased expression of NOS2 protein] which results in decreased chemical synthesis of Nitric Oxide; Cycloheximide inhibits the reaction [[Raloxifene Hydrochloride co-treated with 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid] results in increased expression of NOS2 protein]; Dactinomycin inhibits the reaction [[Raloxifene Hydrochloride co-treated with 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid] results in increased expression of NOS2 protein]; Fulvestrant inhibits the reaction [[Raloxifene Hydrochloride co-treated with 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid] results in increased expression of NOS2 protein]; HMOX1 protein promotes the reaction [[Raloxifene Hydrochloride results in decreased expression of NOS2 protein] which results in decreased chemical synthesis of Nitric Oxide]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Raloxifene Hydrochloride co-treated with 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid] results in increased expression of NOS2 protein]; XDH protein promotes the reaction [[Raloxifene Hydrochloride results in decreased expression of NOS2 protein] which results in decreased chemical synthesis of Nitric Oxide]
Carrageenan inhibits the reaction [Raloxifene Hydrochloride results in increased expression of NOS2 protein]
CTD PMID:15860553 PMID:20888885 PMID:28138957 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nos3 nitric oxide synthase 3 increases expression EXP Raloxifene Hydrochloride results in increased expression of NOS3 mRNA CTD PMID:11779577 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Notch3 notch receptor 3 affects expression ISO Raloxifene Hydrochloride affects the expression of NOTCH3 mRNA CTD PMID:14699072 NCBI chr 7:11,132,984...11,184,025
Ensembl chr 7:11,133,706...11,184,025
JBrowse link
G Npm1 nucleophosmin 1 decreases expression ISO Raloxifene Hydrochloride results in decreased expression of NPM1 mRNA CTD PMID:16514628 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645
Ensembl chr  X:17,739,941...17,751,645
JBrowse link
G Npr2 natriuretic peptide receptor 2 affects expression
multiple interactions
ISO Raloxifene Hydrochloride affects the expression of NPR2 mRNA
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of NPR2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NPR2 mRNA
CTD PMID:14699072 PMID:19059307 NCBI chr 5:57,883,171...57,901,590
Ensembl chr 5:57,883,171...57,901,580
JBrowse link
G Npy1r neuropeptide Y receptor Y1 multiple interactions ISO Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of NPY1R mRNA] CTD PMID:21185374 NCBI chr16:23,037,788...23,047,330
Ensembl chr16:23,037,789...23,046,759
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression
multiple interactions
ISO Raloxifene Hydrochloride results in increased expression of NQO1 protein
ARNT protein affects the reaction [Raloxifene Hydrochloride results in increased expression of NQO1 protein]
CTD PMID:24481452 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NR1D1 mRNA CTD PMID:19059307 NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705
JBrowse link
G Nr2f6 nuclear receptor subfamily 2, group F, member 6 affects expression
multiple interactions
ISO Raloxifene Hydrochloride affects the expression of NR2F6 mRNA
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NR2F6 mRNA
CTD PMID:14699072 PMID:19059307 NCBI chr16:18,046,012...18,053,914
Ensembl chr16:18,046,013...18,053,459
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of NR3C1 mRNA CTD PMID:19059307 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 increases expression ISO Raloxifene Hydrochloride results in increased expression of NR4A1 mRNA CTD PMID:16514628 NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of NR4A3 mRNA CTD PMID:19059307 NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733
JBrowse link
G Nrep neuronal regeneration related protein affects expression ISO Raloxifene Hydrochloride affects the expression of NREP mRNA CTD PMID:14699072 NCBI chr18:25,017,069...25,046,593
Ensembl chr18:25,017,083...25,046,591
JBrowse link
G Nrf1 nuclear respiratory factor 1 multiple interactions
increases expression
ISO fulvestrant inhibits the reaction [Raloxifene Hydrochloride results in increased expression of NRF1 mRNA]; Vehicle Emissions inhibits the reaction [Raloxifene Hydrochloride results in increased expression of NRF1 mRNA] CTD PMID:22105178 NCBI chr 4:58,664,932...58,772,328
Ensembl chr 4:58,664,957...58,825,328
JBrowse link
G Nrg1 neuregulin 1 multiple interactions ISO Raloxifene Hydrochloride inhibits the reaction [[NRG1 protein co-treated with Estradiol] results in increased expression of MYC protein] CTD PMID:26502914 NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884
JBrowse link
G Nrg2 neuregulin 2 increases expression ISO Raloxifene Hydrochloride results in increased expression of NRG2 mRNA CTD PMID:15849065 NCBI chr18:27,616,542...27,798,505
Ensembl chr18:27,619,661...27,798,505
JBrowse link
G Nuak1 NUAK family kinase 1 affects expression
multiple interactions
ISO Raloxifene Hydrochloride affects the expression of NUAK1 mRNA
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NUAK1 mRNA
CTD PMID:14699072 PMID:19059307 NCBI chr 7:19,330,034...19,401,918
Ensembl chr 7:19,329,933...19,401,913
JBrowse link
G Nup160 nucleoporin 160 increases expression ISO Raloxifene Hydrochloride results in increased expression of NUP160 mRNA CTD PMID:16497877 NCBI chr 3:76,665,786...76,729,296
Ensembl chr 3:76,665,786...76,724,565
JBrowse link
G Nus1 NUS1 dehydrodolichyl diphosphate synthase subunit decreases expression ISO Raloxifene Hydrochloride results in decreased expression of NUS1 mRNA CTD PMID:16514628 NCBI chr20:31,811,817...31,838,562
Ensembl chr20:31,811,817...31,838,561
JBrowse link
G Nxf1 nuclear RNA export factor 1 affects expression EXP Raloxifene Hydrochloride affects the expression of NXF1 mRNA CTD PMID:16079270 NCBI chr 1:205,655,442...205,668,637
Ensembl chr 1:205,655,375...205,668,636
JBrowse link
G Ocln occludin multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of OCLN mRNA CTD PMID:19059307 NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150
JBrowse link
G Olfm1 olfactomedin 1 decreases expression ISO Raloxifene Hydrochloride results in decreased expression of OLFM1 mRNA CTD PMID:26865669 NCBI chr 3:11,520,522...11,558,240
Ensembl chr 3:11,520,729...11,558,239
JBrowse link
G Olfml2a olfactomedin-like 2A affects expression ISO Raloxifene Hydrochloride affects the expression of OLFML2A mRNA CTD PMID:14699072 NCBI chr 3:22,688,590...22,717,917
Ensembl chr 3:22,688,598...22,717,909
JBrowse link
G Or10al6 olfactory receptor family 10 subfamily AL member 6 affects expression EXP Raloxifene Hydrochloride affects the expression of OR10AL6 mRNA CTD PMID:16079270 NCBI chr20:738,257...739,607
Ensembl chr20:734,965...811,125
JBrowse link
G Or1f45 olfactory receptor family 1 subfamily F member 45 affects expression EXP Raloxifene Hydrochloride affects the expression of OR1F45 mRNA CTD PMID:16079270 NCBI chr10:11,992,870...11,993,811
Ensembl chr10:11,992,870...11,993,811
Ensembl chr10:11,992,870...11,993,811
JBrowse link
G Osbpl3 oxysterol binding protein-like 3 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of OSBPL3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of OSBPL3 mRNA CTD PMID:19059307 NCBI chr 4:79,346,583...79,523,523
Ensembl chr 4:79,350,349...79,523,393
JBrowse link
G Osbpl7 oxysterol binding protein-like 7 increases expression ISO Raloxifene Hydrochloride results in increased expression of OSBPL7 mRNA CTD PMID:19429434 NCBI chr10:82,035,995...82,053,566
Ensembl chr10:82,036,042...82,053,557
JBrowse link
G Otub2 OTU deubiquitinase, ubiquitin aldehyde binding 2 multiple interactions
decreases expression
ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of OTUB2 mRNA
Raloxifene Hydrochloride results in decreased expression of OTUB2 mRNA
CTD PMID:19059307 PMID:33269387 NCBI chr 6:122,545,067...122,563,657
Ensembl chr 6:122,545,061...122,563,644
JBrowse link
G Otud1 OTU deubiquitinase 1 multiple interactions ISO [SOD1 protein mutant form affects the susceptibility to Raloxifene Hydrochloride] which results in increased expression of OTUD1 mRNA CTD PMID:33269387 NCBI chr17:82,259,920...82,262,770
Ensembl chr17:82,259,840...82,262,995
JBrowse link
G Otud3 OTU deubiquitinase 3 decreases expression
multiple interactions
ISO Raloxifene Hydrochloride results in decreased expression of OTUD3 mRNA
[SOD1 protein mutant form affects the susceptibility to Raloxifene Hydrochloride] which results in decreased expression of OTUD3 mRNA
CTD PMID:33269387 NCBI chr 5:151,135,826...151,162,207
Ensembl chr 5:151,140,059...151,163,560
JBrowse link
G Otud5 OTU deubiquitinase 5 decreases expression ISO Raloxifene Hydrochloride results in decreased expression of OTUD5 mRNA CTD PMID:33269387 NCBI chr  X:14,626,173...14,659,331
Ensembl chr  X:14,626,164...14,659,573
JBrowse link
G Otud7a OTU deubiquitinase 7A decreases expression ISO Raloxifene Hydrochloride results in decreased expression of OTUD7A mRNA CTD PMID:33269387 NCBI chr 1:117,064,428...117,388,217
Ensembl chr 1:117,064,496...117,386,480
JBrowse link
G Otud7b OTU deubiquitinase 7B multiple interactions
increases expression
ISO [SOD1 protein mutant form affects the susceptibility to Raloxifene Hydrochloride] which results in increased expression of OTUD7B mRNA
Raloxifene Hydrochloride results in increased expression of OTUD7B mRNA
CTD PMID:33269387 NCBI chr 2:183,661,955...183,722,584
Ensembl chr 2:183,662,163...183,718,674
JBrowse link
G P2ry14 purinergic receptor P2Y14 multiple interactions ISO Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of P2RY14 mRNA] CTD PMID:18367319 NCBI chr 2:143,372,697...143,413,213
Ensembl chr 2:143,372,697...143,413,141
JBrowse link
G Palld palladin, cytoskeletal associated protein affects expression ISO Raloxifene Hydrochloride affects the expression of PALLD mRNA CTD PMID:14699072 NCBI chr16:28,228,006...28,621,349
Ensembl chr16:27,981,354...28,621,337
JBrowse link
G Papola poly (A) polymerase alpha affects expression EXP Raloxifene Hydrochloride affects the expression of PAPOLA mRNA CTD PMID:16079270 NCBI chr 6:124,682,015...124,734,706
Ensembl chr 6:124,682,105...124,734,468
JBrowse link
G Pappa pappalysin increases expression ISO Raloxifene Hydrochloride results in increased expression of PAPPA mRNA CTD PMID:19429434 NCBI chr 5:78,497,660...78,735,873
Ensembl chr 5:78,498,300...78,730,666
JBrowse link
G Park7 Parkinsonism associated deglycase increases expression ISO Raloxifene Hydrochloride results in increased expression of PARK7 mRNA CTD PMID:33269387 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
multiple interactions
ISO Raloxifene Hydrochloride results in increased cleavage of PARP1 protein
[ESR1 protein co-treated with ESR2 protein] affects the reaction [Raloxifene Hydrochloride results in increased cleavage of PARP1 protein]
CTD PMID:22965848 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pawr pro-apoptotic WT1 regulator increases expression ISO Raloxifene Hydrochloride results in increased expression of PAWR mRNA; Raloxifene Hydrochloride results in increased expression of PAWR protein CTD PMID:20945400 NCBI chr 7:43,645,028...43,725,033
Ensembl chr 7:43,645,084...43,725,028
JBrowse link
G Pax5 paired box 5 increases expression ISO Raloxifene Hydrochloride results in increased expression of PAX5 mRNA CTD PMID:12154049 NCBI chr 5:58,763,334...58,945,719
Ensembl chr 5:58,765,036...58,944,326
JBrowse link
G Pcdh7 protocadherin 7 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of PCDH7 mRNA CTD PMID:19059307 NCBI chr14:52,471,801...52,901,696
Ensembl chr14:52,475,610...52,902,051
Ensembl chr14:52,475,610...52,902,051
JBrowse link
G Pcdhga3 protocadherin gamma subfamily A, 3 increases expression ISO Raloxifene Hydrochloride results in increased expression of PCDHGA3 mRNA CTD PMID:19429434 NCBI chr18:29,499,148...29,667,865
Ensembl chr18:29,493,954...29,667,868
JBrowse link
G Pclaf PCNA clamp associated factor decreases expression ISO Raloxifene Hydrochloride results in decreased expression of PCLAF mRNA CTD PMID:16514628 NCBI chr 8:66,420,606...66,432,994
Ensembl chr 8:66,420,587...66,432,994
Ensembl chr 8:66,420,587...66,432,994
JBrowse link
G Pcna proliferating cell nuclear antigen increases expression
decreases expression
affects expression
multiple interactions
ISO
EXP
Raloxifene Hydrochloride results in increased expression of PCNA protein
Raloxifene Hydrochloride results in decreased expression of PCNA protein
Raloxifene Hydrochloride affects the expression of PCNA protein
[APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of PCNA protein
CTD PMID:15731164 PMID:16009171 PMID:17220163 PMID:24431404 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Pcolce procollagen C-endopeptidase enhancer affects expression
increases expression
EXP Raloxifene Hydrochloride affects the expression of PCOLCE mRNA
Raloxifene Hydrochloride results in increased expression of PCOLCE mRNA
CTD PMID:15576828 PMID:16079270 NCBI chr12:19,084,191...19,090,508
Ensembl chr12:19,084,210...19,090,508
JBrowse link
G Pctp phosphatidylcholine transfer protein multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PCTP mRNA CTD PMID:19059307 NCBI chr10:74,808,887...74,856,260
Ensembl chr10:74,808,887...74,849,867
JBrowse link
G Pdcd5 programmed cell death 5 increases expression ISO Raloxifene Hydrochloride results in increased expression of PDCD5 mRNA CTD PMID:16202921 NCBI chr 1:88,305,869...88,311,200
Ensembl chr 1:88,305,869...88,311,200
JBrowse link
G Pde3b phosphodiesterase 3B increases expression ISO Raloxifene Hydrochloride results in increased expression of PDE3B mRNA CTD PMID:19429434 NCBI chr 1:168,606,762...168,770,078
Ensembl chr 1:168,607,022...168,769,334
JBrowse link
G Pde4d phosphodiesterase 4D increases expression ISO Raloxifene Hydrochloride results in increased expression of PDE4D mRNA CTD PMID:16497877 NCBI chr 2:40,014,933...41,529,190
Ensembl chr 2:40,019,933...41,525,884
JBrowse link
G Pde5a phosphodiesterase 5A decreases expression ISO Raloxifene Hydrochloride results in decreased expression of PDE5A mRNA CTD PMID:19429434 NCBI chr 2:210,858,515...211,003,480
Ensembl chr 2:210,858,063...210,999,701
JBrowse link
G Pdgfra platelet derived growth factor receptor alpha affects expression ISO Raloxifene Hydrochloride affects the expression of PDGFRA mRNA CTD PMID:14699072 NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta affects expression ISO Raloxifene Hydrochloride affects the expression of PDGFRB mRNA CTD PMID:14699072 NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843
JBrowse link
G Pdlim3 PDZ and LIM domain 3 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PDLIM3 mRNA CTD PMID:19059307 NCBI chr16:46,352,460...46,383,680
Ensembl chr16:46,352,467...46,383,657
JBrowse link
G Pdp1 pyruvate dehydrogenase phosphatase catalytic subunit 1 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of PDP1 mRNA CTD PMID:19059307 NCBI chr 5:25,446,843...25,455,107
Ensembl chr 5:25,446,272...25,455,217
JBrowse link
G Pdyn prodynorphin affects expression EXP Raloxifene Hydrochloride affects the expression of PDYN mRNA CTD PMID:16079270 NCBI chr 3:116,900,990...116,913,334
Ensembl chr 3:116,900,992...116,913,334
JBrowse link
G Pdzk1 PDZ domain containing 1 multiple interactions
decreases expression
ISO Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of PDZK1 mRNA]
Raloxifene Hydrochloride results in decreased expression of PDZK1 mRNA
CTD PMID:21185374 PMID:26865669 NCBI chr 2:184,376,161...184,407,514
Ensembl chr 2:184,376,161...184,407,514
JBrowse link
G Per2 period circadian regulator 2 multiple interactions ISO Raloxifene Hydrochloride inhibits the reaction [Estradiol results in decreased expression of PER2 mRNA] CTD PMID:18728223 NCBI chr 9:92,007,289...92,049,551
Ensembl chr 9:92,007,296...92,049,459
JBrowse link
G Pex5 peroxisomal biogenesis factor 5 affects expression EXP Raloxifene Hydrochloride affects the expression of PEX5 mRNA CTD PMID:16079270 NCBI chr 4:157,270,671...157,296,432
Ensembl chr 4:157,270,672...157,296,431
JBrowse link
G Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of PFKFB3 mRNA CTD PMID:19059307 NCBI chr17:66,983,629...67,064,702
Ensembl chr17:66,983,686...67,063,125
JBrowse link
G Pgr progesterone receptor multiple interactions
increases expression
decreases expression
ISO
EXP
[Raloxifene Hydrochloride co-treated with Estradiol] results in increased expression of PGR mRNA; [trichostatin A co-treated with Raloxifene Hydrochloride] results in decreased expression of PGR mRNA; Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of PGR mRNA]; trichostatin A inhibits the reaction [[Raloxifene Hydrochloride co-treated with Estradiol] results in increased expression of PGR mRNA]
Raloxifene Hydrochloride results in increased expression of PGR protein
Raloxifene Hydrochloride results in decreased expression of PGR mRNA; Raloxifene Hydrochloride results in decreased expression of PGR protein
[Estradiol co-treated with Raloxifene Hydrochloride] results in increased expression of PGR mRNA; Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of PGR mRNA]
CTD PMID:11867264 PMID:16837883 PMID:16973256 PMID:21185374 PMID:22476901 More... NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link
G Phc2 polyhomeotic homolog 2 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PHC2 mRNA CTD PMID:19059307 NCBI chr 5:141,000,604...141,099,268
Ensembl chr 5:141,050,842...141,099,268
JBrowse link
G Phf11 PHD finger protein 11 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PHF11 mRNA CTD PMID:19059307 NCBI chr15:33,390,290...33,414,647
Ensembl chr15:33,390,292...33,413,009
JBrowse link
G Phlpp1 PH domain and leucine rich repeat protein phosphatase 1 affects expression EXP Raloxifene Hydrochloride affects the expression of PHLPP mRNA CTD PMID:16079270 NCBI chr13:22,308,532...22,530,978
Ensembl chr13:22,308,548...22,530,977
JBrowse link
G Pias3 protein inhibitor of activated STAT, 3 affects expression EXP Raloxifene Hydrochloride affects the expression of PIAS3 mRNA CTD PMID:16079270 NCBI chr 2:184,232,546...184,241,455
Ensembl chr 2:184,232,571...184,241,480
JBrowse link
G Pign phosphatidylinositol glycan anchor biosynthesis, class N increases expression ISO Raloxifene Hydrochloride results in increased expression of PIGN mRNA CTD PMID:22841776 NCBI chr13:21,659,092...21,812,932
Ensembl chr13:21,662,455...21,806,790
JBrowse link
G Pigr polymeric immunoglobulin receptor affects expression EXP Raloxifene Hydrochloride affects the expression of PIGR mRNA CTD PMID:16079270 NCBI chr13:42,298,905...42,326,877
Ensembl chr13:42,298,914...42,326,875
JBrowse link
G Pik3r3 phosphoinositide-3-kinase regulatory subunit 3 increases expression ISO Raloxifene Hydrochloride results in increased expression of PIK3R3 mRNA CTD PMID:26865669 NCBI chr 5:129,700,925...129,772,591
Ensembl chr 5:129,701,229...129,772,583
JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase affects expression ISO Raloxifene Hydrochloride affects the expression of PIM1 mRNA CTD PMID:14699072 NCBI chr20:7,554,921...7,559,174
Ensembl chr20:7,554,921...7,559,174
JBrowse link
G Pitpnc1 phosphatidylinositol transfer protein, cytoplasmic 1 multiple interactions ISO [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PITPNC1 mRNA CTD PMID:19059307 NCBI chr10:92,163,558...92,428,971
Ensembl chr10:92,167,196...92,429,297
JBrowse link
G Pla2g10 phospholipase A2, group X multiple interactions ISO Raloxifene Hydrochloride promotes the reaction [Estradiol results in increased expression of PLA2G10 mRNA] CTD PMID:21185374 NCBI chr10:1,597,761...1,610,822
Ensembl chr10:1,597,761...1,609,000
JBrowse link
G Pla2g7 phospholipase A2 group VII decreases expression ISO Raloxifene Hydrochloride results in decreased expression of PLA2G7 mRNA CTD PMID:19429434 NCBI chr 9:17,362,214...17,404,476
Ensembl chr 9:17,362,225...17,404,476
JBrowse link
G Plat plasminogen activator, tissue type increases expression ISO Raloxifene Hydrochloride results in increased expression of PLAT protein CTD PMID:16167916 NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
JBrowse link
G Plau plasminogen activator, urokinase multiple interactions
decreases expression
ISO [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of PLAU mRNA
Raloxifene Hydrochloride results in decreased expression of PLAU protein
CTD PMID:16277677 PMID:19059307 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
JBrowse link
G Plaur plasminogen activator, urokinase receptor decreases expression ISO Raloxifene Hydrochloride results in decreased expression of PLAUR mRNA; Raloxifene Hydrochloride results in decreased expression of PLAUR protein CTD PMID:16277677 PMID:26865669 NCBI chr 1:80,053,440...80,068,384
Ensembl chr 1:80,050,324...80,068,595
JBrowse link
G Plekhf2 pleckstrin homology and FYVE domain containing 2 increases expression ISO Raloxifene Hydrochloride results in increased expression of PLEKHF2 mRNA CTD PMID:26865669 NCBI chr 5:24,091,077...24,106,758
Ensembl chr 5:24,090,688...24,106,601
JBrowse link
G Plekhs1 pleckstrin homology domain containing S1 multiple interactions ISO [Raloxifene Hydrochloride co-treated with Estradiol] results in increased expression of PLEKHS1 mRNA CTD PMID:21185374 NCBI chr 1:255,495,634...255,525,353
Ensembl chr 1:255,495,634...255,525,353
JBrowse link
G Plk3 polo-like kinase 3 multiple interactions ISO Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased expression of PLK3 mRNA] CTD PMID:12072388 NCBI chr 5:130,607,142...130,612,317
Ensembl chr 5:130,607,142...130,612,317
JBrowse link
G Plpp1 phospholipid phosphatase 1 affects expression EXP Raloxifene Hydrochloride affects the expression of PLPP1 mRNA CTD PMID:16079270 NCBI chr 2:44,439,002...44,500,430
Ensembl chr 2:44,438,994...44,501,268
JBrowse link
G Plpp3 phospholipid phosphatase 3 affects expression
multiple interactions
ISO Raloxifene Hydrochloride affects the expression of PLPP3 mRNA
ESR1 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of PLPP3 mRNA]
CTD PMID:14699072 NCBI chr 5:119,927,085...120,002,206
Ensembl chr 5:119,927,085...120,002,205
JBrowse link
G Plxnd1 plexin D1 increases expression ISO Raloxifene Hydrochloride results in increased expression of PLXND1 mRNA CTD PMID:19429434 NCBI chr 4:149,002,786...149,043,097
Ensembl chr 4:149,002,784...149,043,244
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression ISO Raloxifene Hydrochloride results in increased expression of PMAIP1 mRNA CTD PMID:16497877 NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429
JBrowse link
G Pmp22 peripheral myelin protein 22 multiple interactions ISO Raloxifene Hydrochloride inhibits the reaction [Estradiol results in decreased expression of PMP22 mRNA] CTD PMID:21185374 NCBI chr10:47,795,709...47,825,715
Ensembl chr10:47,795,709...47,825,714
JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component increases expression ISO Raloxifene Hydrochloride results in increased expression of PMS2 mRNA CTD PMID:16202921 NCBI chr12:10,676,818...10,701,161
Ensembl chr12:10,676,764...10,701,066
JBrowse link
G Podxl podocalyxin-like affects expression ISO Raloxifene Hydrochloride affects the expression of PODXL mRNA CTD PMID:14699072 NCBI chr 4:60,135,124...60,181,829
Ensembl chr 4:60,135,109...60,181,899
JBrowse link
G Polm DNA polymerase mu increases expression ISO Raloxifene Hydrochloride results in increased expression of POLM mRNA CTD PMID:16497877 NCBI chr14:80,707,075...80,716,677
Ensembl chr14:80,706,345...80,717,086
JBrowse link
G Polr2b RNA polymerase II subunit B decreases expression ISO Raloxifene Hydrochloride results in decreased expression of POLR2B mRNA CTD PMID:16514628 NCBI chr14:30,797,228...30,834,916
Ensembl chr14:30,797,228...30,834,916
JBrowse link
G Postn periostin decreases expression ISO Raloxifene Hydrochloride results in decreased expression of POSTN mRNA; Raloxifene Hydrochloride results in decreased expression of POSTN protein CTD PMID:32947957 NCBI chr 2:138,527,714...138,559,098
Ensembl chr 2:138,527,696...138,559,099
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO IWR-1 compound inhibits the reaction [Raloxifene Hydrochloride inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of PPARG protein]]; Raloxifene Hydrochloride inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of PPARG protein] CTD PMID:31470850 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppm1d protein phosphatase, Mg2+/Mn2+ dependent, 1D decreases expression ISO Raloxifene Hydrochloride results in decreased expression of PPM1D mRNA CTD PMID:16514628 NCBI chr10:70,172,603...70,208,607
Ensembl chr10:70,172,603...70,208,607
JBrowse link
G Ppp1r10 protein phosphatase 1, regulatory subunit 10 increases expression ISO Raloxifene Hydrochloride results in increased expression of PPP1R10 mRNA CTD PMID:16497877 NCBI chr20:2,822,995...2,838,125
Ensembl chr20:2,822,995...2,837,611
JBrowse link
G Ppp1r13b protein phosphatase 1, regulatory subunit 13B decreases expression ISO Raloxifene Hydrochloride results in decreased expression of PPP1R13B mRNA CTD PMID:16202921 NCBI chr 6:130,890,682...130,963,845
Ensembl chr 6:130,890,679...130,963,330
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression
affects expression
ISO
EXP
Raloxifene Hydrochloride results in increased expression of PPP1R15A mRNA
Raloxifene Hydrochloride affects the expression of PPP1R15A mRNA
CTD PMID:16079270