|
G |
Aatk |
apoptosis-associated tyrosine kinase |
increases expression |
EXP |
Raloxifene Hydrochloride results in increased expression of AATK mRNA |
CTD |
PMID:15576828 |
|
NCBI chr10:105,290,752...105,327,219
Ensembl chr10:105,291,585...105,327,112
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G |
Abcb1a |
ATP binding cassette subfamily B member 1A |
decreases expression multiple interactions affects activity |
ISO |
Raloxifene Hydrochloride results in decreased expression of ABCB1 mRNA; Raloxifene Hydrochloride results in decreased expression of ABCB1 protein [Cyclosporine co-treated with Raloxifene Hydrochloride] results in decreased expression of ABCB1 mRNA; [Cyclosporine co-treated with Raloxifene Hydrochloride] results in decreased expression of ABCB1 protein ABCB1 protein affects the activity of Raloxifene Hydrochloride |
CTD |
PMID:16959878 PMID:17096884 |
|
NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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|
G |
Abcb9 |
ATP binding cassette subfamily B member 9 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ABCB9 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr12:32,499,213...32,531,932
Ensembl chr12:32,499,225...32,531,931
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|
G |
Abcc1 |
ATP binding cassette subfamily C member 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ABCC1 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
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G |
Abcg1 |
ATP binding cassette subfamily G member 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ABCG1 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
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|
G |
Abhd2 |
abhydrolase domain containing 2, acylglycerol lipase |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of ABHD2 mRNA |
CTD |
PMID:26865669 |
|
NCBI chr 1:133,217,403...133,298,564
Ensembl chr 1:133,217,375...133,299,061
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G |
Abhd5 |
abhydrolase domain containing 5, lysophosphatidic acid acyltransferase |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ABHD5 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 8:122,000,241...122,026,447
Ensembl chr 8:122,000,389...122,026,447
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G |
Abhd8 |
abhydrolase domain containing 8 |
affects response to substance |
ISO |
ABHD8 affects the susceptibility to Raloxifene Hydrochloride |
CTD |
PMID:32934756 |
|
NCBI chr16:18,144,464...18,151,201
Ensembl chr16:18,144,464...18,157,667
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|
G |
Ablim3 |
actin binding LIM protein family, member 3 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ABLIM3 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr18:55,256,135...55,376,629
Ensembl chr18:55,257,583...55,376,380
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|
G |
Acan |
aggrecan |
multiple interactions |
EXP |
Raloxifene Hydrochloride inhibits the reaction [Decitabine results in decreased expression of ACAN mRNA] |
CTD |
PMID:23385821 |
|
NCBI chr 1:132,981,582...133,044,416
Ensembl chr 1:132,981,582...133,043,627
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G |
Ace |
angiotensin I converting enzyme |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of ACE mRNA |
CTD |
PMID:15849065 |
|
NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
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G |
Ache |
acetylcholinesterase |
decreases activity |
ISO |
Raloxifene Hydrochloride results in decreased activity of ACHE protein |
CTD |
PMID:33844597 |
|
NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
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|
G |
Ackr3 |
atypical chemokine receptor 3 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of ACKR3 mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ACKR3 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
|
NCBI chr 9:90,799,682...90,811,246
Ensembl chr 9:90,799,686...90,811,237
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|
G |
Acsl1 |
acyl-CoA synthetase long-chain family member 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ACSL1 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
|
|
G |
Acta2 |
actin alpha 2, smooth muscle |
multiple interactions |
ISO |
Raloxifene Hydrochloride affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of ACTA2 protein] |
CTD |
PMID:32828944 |
|
NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
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|
G |
Acvrl1 |
activin A receptor like type 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of ACVRL1 mRNA; Raloxifene Hydrochloride results in increased expression of ACVRL1 protein |
CTD |
PMID:20135064 |
|
NCBI chr 7:132,239,200...132,256,592
Ensembl chr 7:132,239,729...132,256,591
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|
G |
Adam19 |
ADAM metallopeptidase domain 19 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ADAM19 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr10:30,491,362...30,583,115
Ensembl chr10:30,491,405...30,583,105
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|
G |
Adam22 |
ADAM metallopeptidase domain 22 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of ADAM22 mRNA |
CTD |
PMID:19429434 |
|
NCBI chr 4:25,716,055...25,970,932
Ensembl chr 4:25,715,990...25,964,962
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G |
Adamtsl3 |
ADAMTS-like 3 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ADAMTSL3 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 1:136,288,793...136,596,986
Ensembl chr 1:136,288,793...136,596,986
|
|
G |
Adcy2 |
adenylate cyclase 2 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of ADCY2 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 1:34,375,639...34,822,252
Ensembl chr 1:34,375,895...34,822,236
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G |
Adcyap1 |
adenylate cyclase activating polypeptide 1 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of ADCYAP1 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 9:113,102,632...113,122,500
Ensembl chr 9:113,103,718...113,109,773
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G |
Adgra3 |
adhesion G protein-coupled receptor A3 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of ADGRA3 mRNA |
CTD |
PMID:19429434 |
|
NCBI chr14:60,874,719...60,976,341
Ensembl chr14:60,874,715...60,976,332
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G |
Adgrb2 |
adhesion G protein-coupled receptor B2 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ADGRB2 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 5:142,299,190...142,362,540
Ensembl chr 5:142,331,329...142,362,540
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|
G |
Adgrg1 |
adhesion G protein-coupled receptor G1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ADGRG1 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr19:10,003,963...10,041,122
Ensembl chr19:10,003,975...10,041,108
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G |
Adh1c |
alcohol dehydrogenase 1C (class I), gamma polypeptide |
increases expression |
EXP |
Raloxifene Hydrochloride results in increased expression of ADH1 mRNA |
CTD |
PMID:15576828 |
|
NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892
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G |
Adipoq |
adiponectin, C1Q and collagen domain containing |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of ADIPOQ mRNA |
CTD |
PMID:16643890 |
|
NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
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G |
Adora2a |
adenosine A2a receptor |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of ADORA2A mRNA |
CTD |
PMID:15849065 |
|
NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386
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G |
Adora2b |
adenosine A2B receptor |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ADORA2B mRNA |
CTD |
PMID:19059307 |
|
NCBI chr10:46,940,394...46,956,772
Ensembl chr10:46,940,384...46,956,772
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G |
Adra1a |
adrenoceptor alpha 1A |
decreases expression |
EXP |
Raloxifene Hydrochloride results in decreased expression of ADRA1A mRNA |
CTD |
PMID:20201831 |
|
NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500
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G |
Aebp1 |
AE binding protein 1 |
increases expression |
EXP |
Raloxifene Hydrochloride results in increased expression of AEBP1 mRNA |
CTD |
PMID:15576828 |
|
NCBI chr14:80,738,800...80,748,878
Ensembl chr14:80,738,892...80,748,877
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G |
Ago2 |
argonaute RISC catalytic component 2 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of AGO2 mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of AGO2 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
|
NCBI chr 7:105,018,202...105,105,118
Ensembl chr 7:105,029,120...105,104,974
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G |
Agt |
angiotensinogen |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with Estradiol] inhibits the reaction [AGT protein results in increased phosphorylation of STAT3 protein]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [[Raloxifene Hydrochloride co-treated with Estradiol] inhibits the reaction [AGT protein results in increased phosphorylation of STAT3 protein]] |
CTD |
PMID:17336289 |
|
NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
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G |
Ahcyl1 |
adenosylhomocysteinase-like 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of AHCYL1 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 2:195,294,149...195,328,586
Ensembl chr 2:195,294,153...195,345,815
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|
G |
Ahnak |
AHNAK nucleoprotein |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of AHNAK mRNA |
CTD |
PMID:16514628 |
|
NCBI chr 1:205,882,225...205,970,934
Ensembl chr 1:205,882,273...205,970,926
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|
G |
Ahr |
aryl hydrocarbon receptor |
multiple interactions affects binding affects localization |
ISO |
[Raloxifene Hydrochloride results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA Raloxifene Hydrochloride binds to AHR protein Raloxifene Hydrochloride inhibits the reaction [Methylcholanthrene binds to AHR protein] Raloxifene Hydrochloride affects the localization of AHR protein |
CTD |
PMID:19901195 PMID:24481452 |
|
NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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|
G |
Aimp1 |
aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of AIMP1 mRNA |
CTD |
PMID:12154049 |
|
NCBI chr 2:221,151,907...221,175,458
Ensembl chr 2:221,151,904...221,175,728
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|
G |
Ak3 |
adenylate kinase 3 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of AK3 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 1:226,737,472...226,764,647
Ensembl chr 1:226,739,318...226,764,625
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G |
Akap1 |
A-kinase anchoring protein 1 |
multiple interactions affects expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of AKAP1 mRNA Raloxifene Hydrochloride affects the expression of AKAP1 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
|
NCBI chr10:73,621,021...73,654,123
Ensembl chr10:73,621,883...73,653,896
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G |
Akr7a2 |
aldo-keto reductase family 7, member A2 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of AKR7A2 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 5:151,552,375...151,560,914
Ensembl chr 5:151,552,343...151,560,909
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G |
Akt1 |
AKT serine/threonine kinase 1 |
decreases phosphorylation increases phosphorylation multiple interactions |
ISO EXP |
Raloxifene Hydrochloride results in decreased phosphorylation of AKT1 protein Raloxifene Hydrochloride results in increased phosphorylation of AKT1 protein Raloxifene Hydrochloride inhibits the reaction [TGFA protein results in increased phosphorylation of AKT1 protein] |
CTD |
PMID:15590986 PMID:15876410 PMID:16798746 PMID:25537862 PMID:35007301 |
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NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
Alad |
aminolevulinate dehydratase |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of ALAD mRNA |
CTD |
PMID:26865669 |
|
NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474
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G |
Alas2 |
5'-aminolevulinate synthase 2 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of ALAS2 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr X:19,463,146...19,486,526
Ensembl chr X:19,463,171...19,486,519
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G |
Alcam |
activated leukocyte cell adhesion molecule |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in decreased expression of ALCAM mRNA] |
CTD |
PMID:21185374 |
|
NCBI chr11:48,336,123...48,536,296
Ensembl chr11:48,336,169...48,537,954
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G |
Alox5 |
arachidonate 5-lipoxygenase |
multiple interactions |
ISO |
[APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of ALOX5 mRNA |
CTD |
PMID:24431404 |
|
NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
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G |
Alpl |
alkaline phosphatase, biomineralization associated |
multiple interactions |
EXP |
Raloxifene Hydrochloride inhibits the reaction [Decitabine results in increased expression of ALPL mRNA] |
CTD |
PMID:23385821 |
|
NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
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|
G |
Amigo2 |
adhesion molecule with Ig like domain 2 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of AMIGO2 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 7:128,391,493...128,394,589
Ensembl chr 7:128,390,412...128,394,695
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G |
Amotl2 |
angiomotin like 2 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of AMOTL2 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 8:103,303,368...103,319,161
Ensembl chr 8:103,302,992...103,318,910
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G |
Ang |
angiogenin |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of ANG mRNA |
CTD |
PMID:19429434 |
|
NCBI chr15:24,312,711...24,323,361
|
|
G |
Angptl2 |
angiopoietin-like 2 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ANGPTL2 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 3:16,517,185...16,547,024
Ensembl chr 3:16,517,420...16,548,178
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G |
Angptl7 |
angiopoietin like 7 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of ANGPTL7 mRNA |
CTD |
PMID:16202921 |
|
NCBI chr 5:158,932,096...158,937,281
Ensembl chr 5:158,932,794...158,937,324
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G |
Ank3 |
ankyrin 3 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of ANK3 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr20:18,602,267...19,225,831
Ensembl chr20:18,602,786...19,086,300
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G |
Ankrd1 |
ankyrin repeat domain 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ANKRD1 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919
|
|
G |
Ankrd28 |
ankyrin repeat domain 28 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of ANKRD28 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr16:6,918,487...7,050,244
Ensembl chr16:6,914,336...7,050,249
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G |
Aopep |
aminopeptidase O |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with Estradiol] results in increased expression of AOPEP mRNA |
CTD |
PMID:21185374 |
|
NCBI chr17:1,811,281...2,127,316
Ensembl chr17:1,811,980...2,127,331
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G |
Aox1 |
aldehyde oxidase 1 |
multiple interactions decreases activity |
ISO |
Raloxifene Hydrochloride inhibits the reaction [AOX1 protein results in increased metabolism of zoniporide] Raloxifene Hydrochloride results in decreased activity of AOX1 protein |
CTD |
PMID:20040581 |
|
NCBI chr 9:59,579,621...59,658,772
Ensembl chr 9:59,579,649...59,658,770
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G |
Ap1g1 |
adaptor related protein complex 1 subunit gamma 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of AP1G1 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr19:37,744,633...37,831,134
Ensembl chr19:37,744,633...37,829,167
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G |
Apc |
APC regulator of WNT signaling pathway |
multiple interactions affects response to substance |
ISO |
[APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of ALOX5 mRNA; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of CCL6 mRNA; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of CCND1 mRNA; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of CD24 mRNA; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of CD24 protein; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of CD44 mRNA; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of CD44 protein; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of CTNNB1 mRNA; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of EPCAM mRNA; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of EPCAM protein; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of ESR2 protein; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of LAMB1 mRNA; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of LGR5 mRNA; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of LGR5 protein; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of PCNA protein; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of PTGES mRNA; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of PTGS2 mRNA; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of PTGS2 protein |
CTD |
PMID:24431404 |
|
NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696
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G |
Apex1 |
apurinic/apyrimidinic endodeoxyribonuclease 1 |
multiple interactions increases expression |
EXP |
[Raloxifene Hydrochloride co-treated with Kainic Acid] results in increased expression of APEX1 mRNA Raloxifene Hydrochloride results in increased expression of APEX1 mRNA |
CTD |
PMID:16120186 |
|
NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785
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G |
Apod |
apolipoprotein D |
increases expression multiple interactions |
ISO |
Raloxifene Hydrochloride results in increased expression of APOD mRNA Raloxifene Hydrochloride inhibits the reaction [Estradiol results in decreased expression of APOD protein] |
CTD |
PMID:16514628 PMID:27163517 |
|
NCBI chr11:69,431,261...69,452,306
Ensembl chr11:69,431,260...69,452,305
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G |
Apoe |
apolipoprotein E |
multiple interactions |
ISO |
Raloxifene Hydrochloride affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of ACTA2 protein]; Raloxifene Hydrochloride affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of CD68 protein]; Raloxifene Hydrochloride affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of ICAM1 protein]; Raloxifene Hydrochloride affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of IL6 protein]; Raloxifene Hydrochloride affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of VCAM1 protein]; Raloxifene Hydrochloride affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the phosphorylation of STAT3 protein]; Raloxifene Hydrochloride affects the reaction [[APOE protein affects the susceptibility to IL6 protein] which affects the phosphorylation of STAT3 protein] |
CTD |
PMID:32828944 |
|
NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
|
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G |
App |
amyloid beta precursor protein |
multiple interactions affects binding |
ISO |
Raloxifene Hydrochloride inhibits the reaction [APP protein results in increased expression of TGFB1 mRNA]; Raloxifene Hydrochloride inhibits the reaction [APP protein results in increased expression of TNF mRNA] Raloxifene Hydrochloride binds to APP protein |
CTD |
PMID:31583774 |
|
NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
|
|
G |
Ar |
androgen receptor |
decreases expression affects expression multiple interactions |
ISO EXP |
Raloxifene Hydrochloride results in decreased expression of AR mRNA; Raloxifene Hydrochloride results in decreased expression of AR protein Raloxifene Hydrochloride affects the expression of AR mRNA [Raloxifene Hydrochloride co-treated with Estradiol] results in decreased expression of AR protein |
CTD |
PMID:11867264 PMID:15731164 PMID:16837883 PMID:27163517 |
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NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
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G |
Areg |
amphiregulin |
multiple interactions decreases expression increases expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of AREG mRNA Raloxifene Hydrochloride results in decreased expression of AREG mRNA Raloxifene Hydrochloride inhibits the reaction [Estrogens, Conjugated (USP) results in increased expression of AREG mRNA] Raloxifene Hydrochloride results in increased expression of AREG mRNA |
CTD |
PMID:16514628 PMID:19022889 PMID:19059307 PMID:26865669 |
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NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
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G |
Arg2 |
arginase 2 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of ARG2 mRNA |
CTD |
PMID:22841776 |
|
NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378
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G |
Arhgap29 |
Rho GTPase activating protein 29 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ARHGAP29 mRNA |
CTD |
PMID:14699072 |
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NCBI chr 2:210,060,036...210,132,572
Ensembl chr 2:210,071,199...210,132,028
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G |
Arid5a |
AT-rich interaction domain 5A |
multiple interactions |
ISO |
ARID5A protein inhibits the reaction [Raloxifene Hydrochloride results in increased activity of ESR1 protein] |
CTD |
PMID:15941852 |
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NCBI chr 9:38,534,612...38,549,467
Ensembl chr 9:38,534,590...38,547,597
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G |
Arid5b |
AT-rich interaction domain 5B |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ARID5B mRNA |
CTD |
PMID:14699072 |
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NCBI chr20:20,307,731...20,490,746
Ensembl chr20:20,307,731...20,487,433
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G |
Arl1 |
ARF like GTPase 1 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of ARL1 mRNA |
CTD |
PMID:16079270 |
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NCBI chr 7:23,120,004...23,131,173
Ensembl chr 7:23,119,589...23,131,898
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G |
Arl4c |
ARF like GTPase 4C |
multiple interactions affects expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ARL4C mRNA Raloxifene Hydrochloride affects the expression of ARL4C mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr 9:89,300,335...89,303,770
Ensembl chr 9:89,298,005...89,304,513
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G |
Arnt |
aryl hydrocarbon receptor nuclear translocator |
multiple interactions |
ISO |
ARNT protein affects the reaction [Raloxifene Hydrochloride results in increased expression of CYP1A1 protein]; ARNT protein affects the reaction [Raloxifene Hydrochloride results in increased expression of NQO1 protein] |
CTD |
PMID:24481452 |
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NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580
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G |
Arnt2 |
aryl hydrocarbon receptor nuclear translocator 2 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of ARNT2 mRNA |
CTD |
PMID:16514628 |
|
NCBI chr 1:138,236,235...138,392,868
Ensembl chr 1:138,189,940...138,393,153
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G |
Asb13 |
ankyrin repeat and SOCS box-containing 13 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ASB13 mRNA |
CTD |
PMID:19059307 |
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NCBI chr17:66,564,653...66,583,365
Ensembl chr17:66,562,434...66,583,337
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G |
Asns |
asparagine synthetase (glutamine-hydrolyzing) |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of ASNS mRNA |
CTD |
PMID:16514628 |
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NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
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G |
Atf3 |
activating transcription factor 3 |
multiple interactions increases expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ATF3 mRNA Raloxifene Hydrochloride results in increased expression of ATF3 mRNA |
CTD |
PMID:16497877 PMID:19059307 |
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NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
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G |
Atf7ip |
activating transcription factor 7 interacting protein |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of ATF7IP mRNA |
CTD |
PMID:19429434 |
|
NCBI chr 4:169,385,872...169,471,652
Ensembl chr 4:169,385,872...169,471,650
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G |
Atg12 |
autophagy related 12 |
multiple interactions |
ISO |
Raloxifene Hydrochloride promotes the reaction [ATG12 protein binds to ATG5 protein] |
CTD |
PMID:25537862 |
|
NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418
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G |
Atg5 |
autophagy related 5 |
multiple interactions |
ISO |
Raloxifene Hydrochloride promotes the reaction [ATG12 protein binds to ATG5 protein] |
CTD |
PMID:25537862 |
|
NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209
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G |
Atp1a1 |
ATPase Na+/K+ transporting subunit alpha 1 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of ATP1A1 mRNA |
CTD |
PMID:16079270 |
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NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837
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G |
Atp9a |
ATPase phospholipid transporting 9A (putative) |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ATP9A mRNA |
CTD |
PMID:14699072 |
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NCBI chr 3:157,360,354...157,467,628
Ensembl chr 3:157,360,359...157,467,818
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G |
Atxn3 |
ataxin 3 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of ATXN3 mRNA |
CTD |
PMID:33269387 |
|
NCBI chr 6:121,072,228...121,107,902
Ensembl chr 6:121,074,448...121,107,902
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G |
Aurka |
aurora kinase A |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of AURKA mRNA |
CTD |
PMID:16514628 |
|
NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390
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G |
Avp |
arginine vasopressin |
decreases expression multiple interactions |
ISO |
Raloxifene Hydrochloride results in decreased expression of AVP mRNA 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [Raloxifene Hydrochloride results in decreased expression of AVP mRNA]; GPER1 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of AVP mRNA]; sotrastaurin inhibits the reaction [Raloxifene Hydrochloride results in decreased expression of AVP mRNA]; U 0126 inhibits the reaction [Raloxifene Hydrochloride results in decreased expression of AVP mRNA] |
CTD |
PMID:26200092 |
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NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425
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G |
Axin2 |
axin 2 |
decreases expression multiple interactions |
ISO |
Raloxifene Hydrochloride results in decreased expression of AXIN2 mRNA [Raloxifene Hydrochloride co-treated with PX-866] results in decreased expression of AXIN2 mRNA |
CTD |
PMID:27017931 |
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NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231
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G |
Bad |
BCL2-associated agonist of cell death |
increases cleavage |
ISO |
Raloxifene Hydrochloride results in increased cleavage of BAD protein |
CTD |
PMID:12084714 |
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NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
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G |
Bak1 |
BCL2-antagonist/killer 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of BAK1 mRNA |
CTD |
PMID:16202921 |
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NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
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G |
Bap1 |
BRCA1 associated deubiquitinase 1 |
multiple interactions |
ISO |
[SOD1 protein mutant form affects the susceptibility to Raloxifene Hydrochloride] which results in decreased expression of BAP1 mRNA |
CTD |
PMID:33269387 |
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NCBI chr16:6,446,709...6,455,535
Ensembl chr16:6,446,709...6,455,535
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G |
Bax |
BCL2 associated X, apoptosis regulator |
affects expression increases expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of BAX protein Raloxifene Hydrochloride results in increased expression of BAX mRNA [Raloxifene Hydrochloride co-treated with Resveratrol] results in increased expression of BAX mRNA |
CTD |
PMID:16009171 PMID:29705353 |
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NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bcas1 |
brain enriched myelin associated protein 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with Estradiol] results in increased expression of BCAS1 mRNA |
CTD |
PMID:21185374 |
|
NCBI chr 3:159,136,077...159,219,072
Ensembl chr 3:159,136,083...159,219,106
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G |
Bcl2 |
BCL2, apoptosis regulator |
affects expression decreases expression increases expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of BCL2 protein Raloxifene Hydrochloride results in decreased expression of BCL2 mRNA; Raloxifene Hydrochloride results in decreased expression of BCL2 protein Raloxifene Hydrochloride results in increased expression of BCL2 protein [Resveratrol co-treated with Raloxifene Hydrochloride] results in decreased expression of BCL2 mRNA |
CTD |
PMID:16009171 PMID:16566921 PMID:16973256 PMID:17220163 PMID:20945400 PMID:28430601 PMID:29705353 More...
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NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Bcl2l1 |
Bcl2-like 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of BCL2L1 protein |
CTD |
PMID:28430601 |
|
NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 Ensembl chr 1:141,253,523...141,303,479
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G |
Bcl2l11 |
Bcl2-like 11 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of BCL2L11 mRNA |
CTD |
PMID:19429434 |
|
NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
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G |
Bcl3 |
BCL3, transcription coactivator |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased expression of BCL3 mRNA] |
CTD |
PMID:12072388 |
|
NCBI chr 1:79,471,368...79,485,908
Ensembl chr 1:79,471,369...79,485,607
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G |
Bcl6 |
BCL6, transcription repressor |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of BCL6 mRNA |
CTD |
PMID:16497877 |
|
NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389
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G |
Becn1 |
beclin 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of BECN1 protein |
CTD |
PMID:25537862 |
|
NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
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G |
Bglap |
bone gamma-carboxyglutamate protein |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of BGLAP protein |
CTD |
PMID:17823083 |
|
NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
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G |
Bgn |
biglycan |
increases expression |
ISO EXP |
Raloxifene Hydrochloride results in increased expression of BGN mRNA |
CTD |
PMID:15576828 PMID:19429434 |
|
NCBI chr X:151,197,296...151,209,458
Ensembl chr X:151,197,273...151,209,461
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G |
Bhlhe40 |
basic helix-loop-helix family, member e40 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with PX-866] results in increased expression of BHLHE40 mRNA |
CTD |
PMID:27017931 |
|
NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774
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G |
Birc3 |
baculoviral IAP repeat-containing 3 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of BIRC3 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
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G |
Birc5 |
baculoviral IAP repeat-containing 5 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of BIRC5 protein |
CTD |
PMID:28430601 |
|
NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
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G |
Blzf1 |
basic leucine zipper nuclear factor 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of BLZF1 mRNA |
CTD |
PMID:19429434 |
|
NCBI chr13:76,641,757...76,656,977
Ensembl chr13:76,641,515...76,656,999
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G |
Bmp7 |
bone morphogenetic protein 7 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of BMP7 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788
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G |
Brinp2 |
BMP/retinoic acid inducible neural specific 2 |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of BRINP2 mRNA] |
CTD |
PMID:21185374 |
|
NCBI chr13:70,431,006...70,532,766
Ensembl chr13:70,431,010...70,531,810
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G |
Btg2 |
BTG anti-proliferation factor 2 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of BTG2 mRNA |
CTD |
PMID:22965848 |
|
NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
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G |
C1qb |
complement C1q B chain |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of C1QB mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 5:149,118,843...149,124,394
Ensembl chr 5:149,118,846...149,124,407
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G |
C2cd2 |
C2 calcium-dependent domain containing 2 |
multiple interactions affects expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of C2CD2 mRNA Raloxifene Hydrochloride affects the expression of C2CD2 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr11:37,225,321...37,289,741
Ensembl chr11:37,227,415...37,289,739
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G |
C3 |
complement C3 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of C3 mRNA |
CTD |
PMID:12370124 |
|
NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
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G |
C6h14orf132 |
similar to human chromosome 14 open reading frame 132 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of C14ORF132 mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of C14ORF132 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr 6:124,365,466...124,398,449
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G |
Cabin1 |
calcineurin binding protein 1 |
increases expression |
EXP |
Raloxifene Hydrochloride results in increased expression of CABIN1 mRNA |
CTD |
PMID:15576828 |
|
NCBI chr20:12,893,314...13,015,357
Ensembl chr20:12,893,358...13,015,357
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G |
Cacna1h |
calcium voltage-gated channel subunit alpha1 H |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of CACNA1H mRNA |
CTD |
PMID:21228613 |
|
NCBI chr10:14,390,104...14,448,204
Ensembl chr10:14,390,113...14,448,376
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G |
Cacna1i |
calcium voltage-gated channel subunit alpha1 I |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of CACNA1I mRNA |
CTD |
PMID:21228613 |
|
NCBI chr 7:111,835,996...111,947,418
Ensembl chr 7:111,836,012...111,944,688
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G |
Calb2 |
calbindin 2 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CALB2 mRNA |
CTD |
PMID:17962382 |
|
NCBI chr19:38,114,435...38,141,438
Ensembl chr19:38,114,424...38,141,438
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G |
Cald1 |
caldesmon 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of CALD1 mRNA |
CTD |
PMID:19429434 |
|
NCBI chr 4:63,265,781...63,446,938
Ensembl chr 4:63,265,942...63,446,932
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G |
Calm1 |
calmodulin 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CALM1 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
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G |
Cap2 |
cyclase associated actin cytoskeleton regulatory protein 2 |
decreases expression |
EXP |
Raloxifene Hydrochloride results in decreased expression of CAP2 mRNA |
CTD |
PMID:15576828 |
|
NCBI chr17:18,054,234...18,203,453
Ensembl chr17:18,054,431...18,203,373
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G |
Capn2 |
calpain 2 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of CAPN2 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr13:94,150,244...94,200,969
Ensembl chr13:94,150,240...94,200,969
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G |
Car12 |
carbonic anhydrase 12 |
affects expression multiple interactions decreases expression |
ISO |
Raloxifene Hydrochloride affects the expression of CA12 mRNA [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of CA12 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CA12 mRNA Raloxifene Hydrochloride results in decreased expression of CA12 mRNA |
CTD |
PMID:14699072 PMID:19059307 PMID:26865669 |
|
NCBI chr 8:67,274,739...67,330,428
Ensembl chr 8:67,274,359...67,330,440
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G |
Car4 |
carbonic anhydrase 4 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of CA4 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr10:69,827,945...69,836,501
Ensembl chr10:69,827,945...69,836,501
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G |
Card10 |
caspase recruitment domain family, member 10 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of CARD10 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 7:110,330,460...110,371,551
Ensembl chr 7:110,330,408...110,359,224
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G |
Caskin2 |
cask-interacting protein 2 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CASKIN2 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr10:101,027,196...101,041,429
Ensembl chr10:101,027,260...101,041,414
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G |
Casp3 |
caspase 3 |
increases expression multiple interactions decreases expression increases cleavage |
ISO EXP |
Raloxifene Hydrochloride results in increased expression of CASP3 mRNA; Raloxifene Hydrochloride results in increased expression of CASP3 protein modified form Raloxifene Hydrochloride inhibits the reaction [Decitabine results in increased activity of CASP3 protein] Raloxifene Hydrochloride results in decreased expression of CASP3 mRNA; Raloxifene Hydrochloride results in decreased expression of CASP3 protein Raloxifene Hydrochloride results in increased cleavage of CASP3 protein [Resveratrol co-treated with Raloxifene Hydrochloride] results in decreased expression of CASP3 mRNA; STAT3 protein affects the reaction [Raloxifene Hydrochloride results in increased cleavage of CASP3 protein] |
CTD |
PMID:20945400 PMID:22965848 PMID:23385821 PMID:27999800 PMID:28430601 PMID:28711499 PMID:29705353 More...
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp4 |
caspase 4 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CASP4 mRNA |
CTD |
PMID:12154049 |
|
NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
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G |
Casp7 |
caspase 7 |
multiple interactions affects expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CASP7 mRNA Raloxifene Hydrochloride affects the expression of CASP7 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
|
NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729
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G |
Casp8 |
caspase 8 |
multiple interactions decreases expression increases expression |
ISO |
[Resveratrol co-treated with Raloxifene Hydrochloride] results in decreased expression of CASP8 mRNA Raloxifene Hydrochloride results in decreased expression of CASP8 mRNA; Raloxifene Hydrochloride results in decreased expression of CASP8 protein Raloxifene Hydrochloride results in increased expression of CASP8 mRNA |
CTD |
PMID:27999800 PMID:29705353 |
|
NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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G |
Cat |
catalase |
increases activity |
ISO |
Raloxifene Hydrochloride results in increased activity of CAT protein |
CTD |
PMID:17227729 |
|
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Cav1 |
caveolin 1 |
affects expression multiple interactions increases expression |
ISO EXP |
Raloxifene Hydrochloride affects the expression of CAV1 mRNA fulvestrant inhibits the reaction [Raloxifene Hydrochloride results in increased expression of CAV1 mRNA]; fulvestrant inhibits the reaction [Raloxifene Hydrochloride results in increased expression of CAV1 protein] Raloxifene Hydrochloride results in increased expression of CAV1 mRNA; Raloxifene Hydrochloride results in increased expression of CAV1 protein |
CTD |
PMID:14699072 PMID:17091190 |
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NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
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G |
Cbx1 |
chromobox 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of CBX1 mRNA |
CTD |
PMID:16514628 |
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NCBI chr10:81,770,307...81,789,981
Ensembl chr10:81,770,342...81,791,096
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G |
Cbx3 |
chromobox 3 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of CBX3 mRNA |
CTD |
PMID:19429434 |
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NCBI chr 4:80,545,450...80,559,284
Ensembl chr 4:80,546,010...80,559,283 Ensembl chr 4:80,546,010...80,559,283
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
multiple interactions affects expression decreases activity |
ISO EXP |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CCL2 mRNA; fulvestrant inhibits the reaction [Raloxifene Hydrochloride results in decreased activity of CCL2 protein] Raloxifene Hydrochloride affects the expression of CCL2 mRNA Raloxifene Hydrochloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of CCL2 mRNA] |
CTD |
PMID:14699072 PMID:17006379 PMID:19059307 PMID:25305410 |
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NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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G |
Ccl20 |
C-C motif chemokine ligand 20 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of CCL20 mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CCL20 mRNA Fulvestrant inhibits the reaction [Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased expression of CCL20 protein]]; Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased expression of CCL20 protein] |
CTD |
PMID:14699072 PMID:19059307 PMID:24722370 |
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NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629
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G |
Ccl3 |
C-C motif chemokine ligand 3 |
multiple interactions decreases expression |
ISO |
Raloxifene Hydrochloride inhibits the reaction [ESR1 protein binds to CCL3 promoter]; Raloxifene Hydrochloride inhibits the reaction [RELA protein binds to CCL3 promoter] Raloxifene Hydrochloride results in decreased expression of CCL3 mRNA |
CTD |
PMID:16497877 |
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NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
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G |
Ccl5 |
C-C motif chemokine ligand 5 |
increases expression decreases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CCL5 mRNA Raloxifene Hydrochloride results in decreased expression of CCL5 protein |
CTD |
PMID:12154049 PMID:16842799 |
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NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
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G |
Ccl9 |
C-C motif chemokine ligand 9 |
multiple interactions |
ISO |
[APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of CCL6 mRNA |
CTD |
PMID:24431404 |
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NCBI chr10:68,366,486...68,371,408
Ensembl chr10:68,366,487...68,371,369
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G |
Ccn3 |
cellular communication network factor 3 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of CCN3 mRNA |
CTD |
PMID:19059307 |
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NCBI chr 7:86,094,000...86,101,022
Ensembl chr 7:86,094,000...86,101,019
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G |
Ccna2 |
cyclin A2 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CCNA2 mRNA; Raloxifene Hydrochloride results in increased expression of CCNA2 protein |
CTD |
PMID:17445807 |
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NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
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G |
Ccnb1 |
cyclin B1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CCNB1 mRNA; Raloxifene Hydrochloride results in increased expression of CCNB1 protein |
CTD |
PMID:12154049 PMID:17445807 |
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NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
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G |
Ccnd1 |
cyclin D1 |
multiple interactions affects expression decreases expression |
ISO EXP |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CCND1 mRNA; [Raloxifene Hydrochloride co-treated with PX-866] results in decreased expression of CCND1 mRNA Raloxifene Hydrochloride affects the expression of CCND1 mRNA Raloxifene Hydrochloride results in decreased expression of CCND1 mRNA [Raloxifene Hydrochloride co-treated with Bexarotene] affects the reaction [Azoxymethane affects the expression of CCND1 mRNA]; [Raloxifene Hydrochloride co-treated with Bexarotene] affects the reaction [Azoxymethane affects the expression of CCND1 protein]; Raloxifene Hydrochloride affects the reaction [Azoxymethane affects the expression of CCND1 mRNA]; Raloxifene Hydrochloride affects the reaction [Azoxymethane affects the expression of CCND1 protein] [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of CCND1 mRNA |
CTD |
PMID:14699072 PMID:19059307 PMID:22965848 PMID:24080207 PMID:24431404 PMID:26865669 PMID:27017931 More...
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NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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G |
Ccne2 |
cyclin E2 |
multiple interactions decreases expression |
ISO |
[Raloxifene Hydrochloride co-treated with PX-866] results in decreased expression of CCNE2 mRNA Raloxifene Hydrochloride results in decreased expression of CCNE2 protein |
CTD |
PMID:26660119 |
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NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632
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G |
Ccng2 |
cyclin G2 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CCNG2 mRNA |
CTD |
PMID:16497877 PMID:26865669 |
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NCBI chr14:14,804,321...14,812,819
Ensembl chr14:14,804,322...14,812,830
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G |
Cd200 |
Cd200 molecule |
decreases expression |
EXP |
Raloxifene Hydrochloride results in decreased expression of CD200 mRNA |
CTD |
PMID:15576828 |
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NCBI chr11:55,410,166...55,437,527
Ensembl chr11:55,410,196...55,501,648
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G |
Cd24 |
CD24 molecule |
increases expression multiple interactions |
ISO |
Raloxifene Hydrochloride results in increased expression of CD24 mRNA [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of CD24 mRNA; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of CD24 protein |
CTD |
PMID:16514628 PMID:24431404 |
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NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662
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G |
Cd3g |
CD3 gamma subunit of T-cell receptor complex |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of CD3G mRNA |
CTD |
PMID:16079270 |
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NCBI chr 8:45,280,797...45,287,271
Ensembl chr 8:45,281,204...45,287,147
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G |
Cd40 |
CD40 molecule |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Lipopolysaccharides results in increased expression of CD40 protein] |
CTD |
PMID:16081843 |
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NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
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G |
Cd44 |
CD44 molecule |
decreases expression multiple interactions |
ISO |
Raloxifene Hydrochloride results in decreased expression of CD44 mRNA [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of CD44 mRNA; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of CD44 protein |
CTD |
PMID:24431404 PMID:26865669 |
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NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
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G |
Cd52 |
CD52 molecule |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of CD52 mRNA |
CTD |
PMID:16079270 |
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NCBI chr 5:146,319,789...146,321,348
Ensembl chr 5:146,319,969...146,321,348
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G |
Cd68 |
Cd68 molecule |
multiple interactions |
ISO |
Raloxifene Hydrochloride affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of CD68 protein] |
CTD |
PMID:32828944 |
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NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697
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G |
Cd74 |
CD74 molecule |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of CD74 mRNA |
CTD |
PMID:16079270 |
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NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003
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G |
Cd80 |
Cd80 molecule |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Lipopolysaccharides results in increased expression of CD80 protein] |
CTD |
PMID:16081843 |
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NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030
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G |
Cd86 |
CD86 molecule |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Lipopolysaccharides results in increased expression of CD86 protein] |
CTD |
PMID:16081843 |
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NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
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G |
Cd8a |
CD8 subunit alpha |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of CD8A mRNA |
CTD |
PMID:16079270 |
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NCBI chr 4:103,365,804...103,370,041
Ensembl chr 4:103,365,804...103,370,040
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G |
Cdc6 |
cell division cycle 6 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with PX-866] results in decreased expression of CDC6 mRNA |
CTD |
PMID:26660119 |
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NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011
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G |
Cdh2 |
cadherin 2 |
affects expression multiple interactions |
ISO EXP |
Raloxifene Hydrochloride affects the expression of CDH2 mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CDH2 mRNA |
CTD |
PMID:14699072 PMID:16079270 PMID:19059307 |
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NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
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G |
Cdh6 |
cadherin 6 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of CDH6 mRNA |
CTD |
PMID:16079270 |
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NCBI chr 2:62,079,139...62,225,298
Ensembl chr 2:62,079,137...62,225,228
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G |
Cdk1 |
cyclin-dependent kinase 1 |
multiple interactions |
ISO |
Raloxifene Hydrochloride promotes the reaction [Estradiol results in increased expression of CDK1 mRNA]; trichostatin A inhibits the reaction [Raloxifene Hydrochloride promotes the reaction [Estradiol results in increased expression of CDK1 mRNA]] |
CTD |
PMID:22476901 |
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NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
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G |
Cdk2 |
cyclin dependent kinase 2 |
multiple interactions |
EXP |
[Raloxifene Hydrochloride co-treated with Bexarotene] affects the reaction [Azoxymethane affects the expression of CDK2 protein] |
CTD |
PMID:24080207 |
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NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
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G |
Cdk5r1 |
cyclin-dependent kinase 5 regulatory subunit 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CDK5R1 mRNA |
CTD |
PMID:19059307 |
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NCBI chr10:65,484,266...65,485,467
Ensembl chr10:65,483,941...65,488,456
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G |
Cdk5rap3 |
CDK5 regulatory subunit associated protein 3 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of CDK5RAP3 mRNA |
CTD |
PMID:16079270 |
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NCBI chr10:81,894,393...81,903,581
Ensembl chr10:81,894,393...81,903,590
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
increases expression multiple interactions |
ISO EXP |
Raloxifene Hydrochloride results in increased expression of CDKN1A mRNA; Raloxifene Hydrochloride results in increased expression of CDKN1A protein [Raloxifene Hydrochloride co-treated with Bexarotene] affects the reaction [Azoxymethane affects the expression of CDKN1A protein] [Raloxifene Hydrochloride co-treated with PX-866] results in increased expression of CDKN1A mRNA |
CTD |
PMID:12154049 PMID:16497877 PMID:24080207 PMID:27017931 |
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NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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G |
Cdkn1b |
cyclin-dependent kinase inhibitor 1B |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CDKN1B protein |
CTD |
PMID:16536755 PMID:22965848 |
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NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
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G |
Cdo1 |
cysteine dioxygenase type 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CDO1 mRNA |
CTD |
PMID:19059307 |
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NCBI chr18:39,432,473...39,447,253
Ensembl chr18:39,432,474...39,447,296
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G |
Cdon |
cell adhesion associated, oncogene regulated |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of CDON mRNA |
CTD |
PMID:14699072 |
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NCBI chr 8:33,775,123...33,861,635
Ensembl chr 8:33,806,183...33,859,033
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G |
Cebpa |
CCAAT/enhancer binding protein alpha |
decreases expression multiple interactions |
ISO |
Raloxifene Hydrochloride results in decreased expression of CEBPA mRNA IWR-1 compound inhibits the reaction [Raloxifene Hydrochloride inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CEBPA protein]]; Raloxifene Hydrochloride inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CEBPA protein] |
CTD |
PMID:15849065 PMID:31470850 |
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NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
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G |
Cebpb |
CCAAT/enhancer binding protein beta |
affects expression multiple interactions increases expression |
ISO |
Raloxifene Hydrochloride affects the expression of CEBPB mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CEBPB mRNA Raloxifene Hydrochloride results in increased expression of CEBPB mRNA |
CTD |
PMID:14699072 PMID:16497877 PMID:19059307 |
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NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
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G |
Cenpa |
centromere protein A |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of CENPA mRNA |
CTD |
PMID:16514628 |
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NCBI chr 6:25,700,142...25,711,767
Ensembl chr 6:25,700,142...25,711,675
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G |
Cers6 |
ceramide synthase 6 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CERS6 mRNA |
CTD |
PMID:19059307 |
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NCBI chr 3:53,630,637...53,879,692
Ensembl chr 3:53,630,959...53,876,848
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G |
Cfd |
complement factor D |
increases expression |
EXP |
Raloxifene Hydrochloride results in increased expression of CFD mRNA |
CTD |
PMID:15576828 |
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NCBI chr 7:9,813,148...9,814,871
Ensembl chr 7:9,813,150...9,815,053
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G |
Chrd |
chordin |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of CHRD mRNA |
CTD |
PMID:14699072 |
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NCBI chr11:80,171,994...80,181,166
Ensembl chr11:80,171,994...80,180,673
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G |
Cish |
cytokine inducible SH2-containing protein |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased expression of CISH mRNA] |
CTD |
PMID:12072388 |
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NCBI chr 8:107,972,306...107,977,254
Ensembl chr 8:107,972,306...107,977,250
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G |
Ckb |
creatine kinase B |
increases activity multiple interactions |
ISO EXP |
Raloxifene Hydrochloride results in increased activity of CKB protein Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased activity of CKB protein] |
CTD |
PMID:16621514 PMID:17029789 |
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NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315
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G |
Clcn4 |
chloride voltage-gated channel 4 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CLCN4 mRNA |
CTD |
PMID:19059307 |
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NCBI chr X:23,729,194...23,795,391
Ensembl chr X:23,729,338...23,793,238
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G |
Clcn6 |
chloride voltage-gated channel 6 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CLCN6 mRNA |
CTD |
PMID:16497877 |
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NCBI chr 5:158,434,299...158,465,174
Ensembl chr 5:158,434,299...158,465,059
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G |
Clic4 |
chloride intracellular channel 4 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CLIC4 mRNA |
CTD |
PMID:16497877 |
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NCBI chr 5:147,453,702...147,513,455
Ensembl chr 5:147,453,712...147,513,452
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G |
Clk1 |
CDC-like kinase 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CLK1 mRNA |
CTD |
PMID:12154049 |
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NCBI chr 9:59,947,774...59,959,002
Ensembl chr 9:59,947,764...59,957,000
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G |
Clmn |
calmin |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CLMN mRNA |
CTD |
PMID:26865669 |
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NCBI chr 6:123,707,710...123,807,283
Ensembl chr 6:123,713,507...123,807,272
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G |
Clstn1 |
calsyntenin 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of CLSTN1 mRNA |
CTD |
PMID:16514628 |
|
NCBI chr 5:160,031,235...160,094,585
Ensembl chr 5:160,031,308...160,094,583
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G |
Cltb |
clathrin, light chain B |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of CLTB mRNA |
CTD |
PMID:14699072 |
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NCBI chr17:10,001,512...10,019,201
Ensembl chr17:10,001,513...10,019,169
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G |
Clu |
clusterin |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CLU mRNA |
CTD |
PMID:12370124 PMID:16202921 |
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NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
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G |
Cnbp |
CCHC-type zinc finger, nucleic acid binding protein |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CNBP mRNA |
CTD |
PMID:12154049 |
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NCBI chr 4:120,302,768...120,311,694
Ensembl chr 4:120,302,771...120,311,637
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G |
Col10a1 |
collagen type X alpha 1 chain |
multiple interactions |
EXP |
Raloxifene Hydrochloride inhibits the reaction [Decitabine results in increased expression of COL10A1 mRNA] |
CTD |
PMID:23385821 |
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NCBI chr20:38,183,103...38,189,488
Ensembl chr20:38,182,494...38,189,494
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G |
Col11a1 |
collagen type XI alpha 1 chain |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of COL11A1 mRNA |
CTD |
PMID:16079270 |
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NCBI chr 2:201,820,715...202,013,853
Ensembl chr 2:201,820,715...202,013,853
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G |
Col1a2 |
collagen type I alpha 2 chain |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of COL1A2 mRNA |
CTD |
PMID:19401787 |
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NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
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G |
Col26a1 |
collagen type XXVI alpha 1 chain |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of COL26A1 mRNA |
CTD |
PMID:17962382 |
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NCBI chr12:19,792,693...19,938,556
Ensembl chr12:19,792,728...19,938,556
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G |
Col2a1 |
collagen type II alpha 1 chain |
multiple interactions |
EXP |
Raloxifene Hydrochloride promotes the reaction [Decitabine results in decreased expression of COL2A1 mRNA] |
CTD |
PMID:23385821 |
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NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546
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G |
Col5a1 |
collagen type V alpha 1 chain |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of COL5A1 mRNA |
CTD |
PMID:16079270 |
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NCBI chr 3:11,208,429...11,356,715
Ensembl chr 3:11,208,512...11,354,588
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G |
Col5a2 |
collagen type V alpha 2 chain |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of COL5A2 mRNA |
CTD |
PMID:16079270 |
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NCBI chr 9:47,448,741...47,598,134
Ensembl chr 9:47,448,736...47,598,154
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G |
Copb2 |
COPI coat complex subunit beta 2 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of COPB2 mRNA |
CTD |
PMID:16514628 |
|
NCBI chr 8:99,161,324...99,183,452
Ensembl chr 8:99,161,350...99,185,197
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G |
Cpb2 |
carboxypeptidase B2 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of CPB2 protein |
CTD |
PMID:16167916 |
|
NCBI chr15:50,557,722...50,606,569
Ensembl chr15:50,557,717...50,606,556
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G |
Cpe |
carboxypeptidase E |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of CPE mRNA |
CTD |
PMID:16079270 |
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NCBI chr16:25,030,276...25,142,231
Ensembl chr16:25,030,276...25,142,233
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G |
Cpm |
carboxypeptidase M |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CPM mRNA |
CTD |
PMID:19429434 |
|
NCBI chr 7:53,225,647...53,286,220
Ensembl chr 7:53,225,696...53,286,220
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G |
Creb1 |
cAMP responsive element binding protein 1 |
increases phosphorylation |
EXP |
Raloxifene Hydrochloride results in increased phosphorylation of CREB1 protein |
CTD |
PMID:24782323 |
|
NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
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G |
Crebbp |
CREB binding protein |
multiple interactions |
ISO |
Raloxifene Hydrochloride promotes the reaction [CREBBP protein binds to IGF1 promoter]; Raloxifene Hydrochloride promotes the reaction [CREBBP protein binds to PTGS2 promoter] |
CTD |
PMID:17872375 |
|
NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888
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G |
Crispld2 |
cysteine-rich secretory protein LCCL domain containing 2 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of CRISPLD2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CRISPLD2 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr19:48,053,153...48,111,485
Ensembl chr19:48,053,287...48,110,465
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G |
Crybb2 |
crystallin, beta B2 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of CRYBB2 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr12:43,569,747...43,579,671
Ensembl chr12:43,569,747...43,579,671
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G |
Csdc2 |
cold shock domain containing C2 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CSDC2 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 7:113,451,998...113,466,464
Ensembl chr 7:113,451,998...113,466,463
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G |
Csf1 |
colony stimulating factor 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CSF1 mRNA |
CTD |
PMID:12154049 |
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NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704
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G |
Csf1r |
colony stimulating factor 1 receptor |
multiple interactions |
EXP |
[9,10-Dimethyl-1,2-benzanthracene co-treated with Raloxifene Hydrochloride co-treated with Fluoxetine] affects the expression of CSF1R protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with Raloxifene Hydrochloride] affects the expression of CSF1R protein |
CTD |
PMID:31332895 |
|
NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
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G |
Csf2 |
colony stimulating factor 2 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of CSF2 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
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G |
Csf3 |
colony stimulating factor 3 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of CSF3 mRNA |
CTD |
PMID:16298037 |
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NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
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G |
Ctnnb1 |
catenin beta 1 |
multiple interactions increases expression |
ISO EXP |
[APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of CTNNB1 mRNA; IWR-1 compound inhibits the reaction [Raloxifene Hydrochloride inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CTNNB1 protein]]; Raloxifene Hydrochloride inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CTNNB1 protein] Raloxifene Hydrochloride results in increased expression of CTNNB1 protein [Raloxifene Hydrochloride co-treated with Bexarotene] affects the reaction [Azoxymethane affects the expression of CTNNB1 mRNA]; [Raloxifene Hydrochloride co-treated with Bexarotene] affects the reaction [Azoxymethane affects the expression of CTNNB1 protein] |
CTD |
PMID:24080207 PMID:24431404 PMID:25571714 PMID:31470850 |
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NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
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G |
Ctsb |
cathepsin B |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of CTSB mRNA |
CTD |
PMID:16079270 |
|
NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
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G |
Ctsh |
cathepsin H |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CTSH mRNA |
CTD |
PMID:16514628 |
|
NCBI chr 8:90,608,941...90,627,824
Ensembl chr 8:90,608,941...90,627,824
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G |
Ctsk |
cathepsin K |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of CTSK mRNA |
CTD |
PMID:17166402 |
|
NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550
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G |
Cuedc1 |
CUE domain containing 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CUEDC1 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr10:72,892,637...72,986,546
Ensembl chr10:72,892,637...72,986,542
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G |
Cxadr |
CXADR, Ig-like cell adhesion molecule |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of CXADR mRNA |
CTD |
PMID:14699072 |
|
NCBI chr11:16,982,864...17,030,078
Ensembl chr11:16,982,860...17,030,046
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G |
Cxcl10 |
C-X-C motif chemokine ligand 10 |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of CXCL10 mRNA]; Raloxifene Hydrochloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of CXCL10 protein] |
CTD |
PMID:19533603 |
|
NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
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G |
Cxcl12 |
C-X-C motif chemokine ligand 12 |
multiple interactions decreases expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CXCL12 mRNA; Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of CXCL12 mRNA]; Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased secretion of CXCL12 protein] Raloxifene Hydrochloride results in decreased expression of CXCL12 mRNA |
CTD |
PMID:19059307 PMID:20549624 PMID:21185374 PMID:26865669 |
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NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
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G |
Cxcl2 |
C-X-C motif chemokine ligand 2 |
multiple interactions |
EXP |
Raloxifene Hydrochloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of CXCL2 mRNA] |
CTD |
PMID:25305410 |
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NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
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G |
Cylc2 |
cylicin 2 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CYLC2 mRNA |
CTD |
PMID:19429434 |
|
NCBI chr 5:65,554,320...65,576,251
Ensembl chr 5:65,554,309...65,589,282
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G |
Cyld |
CYLD lysine 63 deubiquitinase |
increases expression multiple interactions |
ISO |
Raloxifene Hydrochloride results in increased expression of CYLD mRNA [SOD1 protein mutant form affects the susceptibility to Raloxifene Hydrochloride] which results in decreased expression of CYLD mRNA |
CTD |
PMID:33269387 |
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NCBI chr19:18,310,632...18,373,696
Ensembl chr19:18,314,019...18,373,658
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G |
Cyp19a1 |
cytochrome P450, family 19, subfamily a, polypeptide 1 |
multiple interactions decreases expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CYP19A1 mRNA Raloxifene Hydrochloride results in decreased expression of CYP19A1 mRNA |
CTD |
PMID:10704911 PMID:19059307 |
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NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
multiple interactions increases expression |
ISO EXP |
[Raloxifene Hydrochloride results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA; Raloxifene Hydrochloride inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein] Raloxifene Hydrochloride results in increased expression of CYP1A1 mRNA; Raloxifene Hydrochloride results in increased expression of CYP1A1 protein ARNT protein affects the reaction [Raloxifene Hydrochloride results in increased expression of CYP1A1 protein] |
CTD |
PMID:18493746 PMID:19901195 PMID:24481452 |
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NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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G |
Cyp24a1 |
cytochrome P450, family 24, subfamily a, polypeptide 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CYP24A1 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 3:159,275,947...159,290,383
Ensembl chr 3:159,275,947...159,290,383
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G |
Cyp26a1 |
cytochrome P450, family 26, subfamily a, polypeptide 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of CYP26A1 mRNA |
CTD |
PMID:29990529 |
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NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204
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G |
Cyp26b1 |
cytochrome P450, family 26, subfamily b, polypeptide 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CYP26B1 mRNA |
CTD |
PMID:19059307 |
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NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628
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G |
Cyp27a1 |
cytochrome P450, family 27, subfamily a, polypeptide 1 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of CYP27A1 mRNA |
CTD |
PMID:16079270 |
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NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
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G |
Cyp27b1 |
cytochrome P450, family 27, subfamily b, polypeptide 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CYP27B1 mRNA |
CTD |
PMID:15795327 |
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NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241
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G |
Cyp2a1 |
cytochrome P450, family 2, subfamily a, polypeptide 1 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of CYP2A1 mRNA |
CTD |
PMID:16079270 |
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NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887
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G |
Cyp2c79 |
cytochrome P450, family 2, subfamily c, polypeptide 79 |
decreases activity |
ISO |
Raloxifene Hydrochloride results in decreased activity of CYP2C8 protein |
CTD |
PMID:15601807 |
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G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
decreases activity multiple interactions |
ISO |
Raloxifene Hydrochloride results in decreased activity of CYP3A4 protein Raloxifene Hydrochloride inhibits the reaction [CYP3A4 protein results in increased oxidation of 7-benzyloxy-4-trifluoromethylcoumarin] |
CTD |
PMID:15860655 PMID:19299527 PMID:23721565 |
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NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
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G |
Dact1 |
dishevelled-binding antagonist of beta-catenin 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of DACT1 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 6:89,790,676...89,818,254
Ensembl chr 6:89,790,644...89,817,906
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G |
Dag1 |
dystroglycan 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of DAG1 mRNA |
CTD |
PMID:16497877 |
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NCBI chr 8:108,890,926...108,955,611
Ensembl chr 8:108,890,929...108,952,325
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G |
Daxx |
death-domain associated protein |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of DAXX mRNA |
CTD |
PMID:14699072 |
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NCBI chr20:4,970,090...4,976,145
Ensembl chr20:4,970,092...4,975,843
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G |
Dbp |
D-box binding PAR bZIP transcription factor |
increases expression |
EXP |
Raloxifene Hydrochloride results in increased expression of DBP mRNA |
CTD |
PMID:15576828 |
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NCBI chr 1:96,175,796...96,180,745
Ensembl chr 1:96,175,440...96,180,745
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G |
Dcbld2 |
discoidin, CUB and LCCL domain containing 2 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of DCBLD2 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr11:42,125,525...42,179,927
Ensembl chr11:42,125,787...42,179,697
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G |
Ddit4 |
DNA-damage-inducible transcript 4 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of DDIT4 mRNA |
CTD |
PMID:14699072 |
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NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
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G |
Ddx21 |
DExD-box helicase 21 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of DDX21 mRNA |
CTD |
PMID:16514628 |
|
NCBI chr20:30,534,319...30,554,513
Ensembl chr20:30,534,319...30,554,543
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G |
Ddx3y |
DEAD box helicase 3, Y-linked |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of DDX3Y mRNA |
CTD |
PMID:16514628 |
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NCBI chr Y:1,115,095...1,135,754
Ensembl chr Y:1,116,309...1,135,706
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G |
Ddx50 |
DExD-box helicase 50 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of DDX50 mRNA |
CTD |
PMID:16079270 |
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NCBI chr20:30,561,623...30,591,324
Ensembl chr20:30,560,544...30,591,152
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G |
Defb1 |
defensin beta 1 |
multiple interactions |
ISO |
[Progesterone co-treated with Raloxifene Hydrochloride] results in increased expression of DEFB1 mRNA |
CTD |
PMID:18367319 |
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NCBI chr16:70,298,862...70,313,604
Ensembl chr16:70,298,863...70,313,604
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G |
Depp1 |
DEPP autophagy regulator 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of DEPP1 mRNA |
CTD |
PMID:16298037 |
|
NCBI chr 4:149,910,794...149,913,013
Ensembl chr 4:149,910,779...149,914,542
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G |
Desi2 |
desumoylating isopeptidase 2 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of DESI2 mRNA |
CTD |
PMID:33269387 |
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NCBI chr13:89,961,767...90,011,255
Ensembl chr13:89,961,934...90,016,416
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G |
Dhcr24 |
24-dehydrocholesterol reductase |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of DHCR24 mRNA |
CTD |
PMID:15585566 |
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NCBI chr 5:121,344,552...121,371,124
Ensembl chr 5:121,344,575...121,371,137
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G |
Dhrs2 |
dehydrogenase/reductase 2 |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of DHRS2 mRNA] |
CTD |
PMID:21185374 |
|
NCBI chr15:28,688,881...28,703,646
Ensembl chr15:28,688,940...28,703,644
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G |
Dhx9 |
DExH-box helicase 9 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of DHX9 mRNA |
CTD |
PMID:16514628 |
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NCBI chr13:65,602,322...65,639,098
Ensembl chr13:65,602,323...65,639,069
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G |
Dicer1 |
dicer 1 ribonuclease III |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of DICER1 mRNA |
CTD |
PMID:16497877 |
|
NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965
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G |
Dkk1 |
dickkopf WNT signaling pathway inhibitor 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of DKK1 protein |
CTD |
PMID:22067277 |
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NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202
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G |
Dkk2 |
dickkopf WNT signaling pathway inhibitor 2 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of DKK2 mRNA |
CTD |
PMID:19429434 |
|
NCBI chr 2:220,568,338...220,660,225
Ensembl chr 2:220,568,338...220,660,225
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G |
Dmbt1 |
deleted in malignant brain tumors 1 |
increases expression |
EXP ISO |
Raloxifene Hydrochloride results in increased expression of DMBT1 mRNA; Raloxifene Hydrochloride results in increased expression of DMBT1 protein |
CTD |
PMID:15564322 |
|
NCBI chr 1:185,617,469...185,696,476
Ensembl chr 1:185,617,294...185,696,478
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G |
Dnaja1 |
DnaJ heat shock protein family (Hsp40) member A1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of DNAJA1 mRNA |
CTD |
PMID:16514628 |
|
NCBI chr 5:55,842,414...55,853,326
Ensembl chr 5:55,842,426...55,853,967
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G |
Dnajb1 |
DnaJ heat shock protein family (Hsp40) member B1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of DNAJB1 mRNA |
CTD |
PMID:16497877 |
|
NCBI chr19:24,522,731...24,526,419
Ensembl chr19:24,522,717...24,526,458
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G |
Dnajb4 |
DnaJ heat shock protein family (Hsp40) member B4 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of DNAJB4 mRNA |
CTD |
PMID:16497877 |
|
NCBI chr 2:241,129,346...241,159,272
Ensembl chr 2:241,130,340...241,159,089
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G |
Dnajb9 |
DnaJ heat shock protein family (Hsp40) member B9 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of DNAJB9 mRNA |
CTD |
PMID:16497877 |
|
NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063
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G |
Dnmbp |
dynamin binding protein |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of DNMBP mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 1:242,736,189...242,829,431
Ensembl chr 1:242,736,189...242,802,604
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G |
Dock9 |
dedicator of cytokinesis 9 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of DOCK9 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr15:98,611,518...98,883,306
Ensembl chr15:98,618,084...98,883,153
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G |
Dram1 |
DNA-damage regulated autophagy modulator 1 |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in decreased expression of DRAM1 mRNA] |
CTD |
PMID:21185374 |
|
NCBI chr 7:22,742,794...22,776,888
Ensembl chr 7:22,742,849...22,776,765
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G |
Drd5 |
dopamine receptor D5 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of DRD5 mRNA |
CTD |
PMID:19429434 |
|
NCBI chr14:72,487,950...72,491,050
Ensembl chr14:72,489,347...72,490,774
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G |
Dusp2 |
dual specificity phosphatase 2 |
decreases expression multiple interactions |
ISO |
Raloxifene Hydrochloride results in decreased expression of DUSP2 mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of DUSP2 mRNA |
CTD |
PMID:16497877 PMID:19059307 |
|
NCBI chr 3:114,556,325...114,558,510
Ensembl chr 3:114,556,325...114,558,499
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G |
Dusp4 |
dual specificity phosphatase 4 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of DUSP4 mRNA |
CTD |
PMID:16497877 |
|
NCBI chr16:57,376,659...57,398,161
Ensembl chr16:57,377,229...57,398,138
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G |
Dusp5 |
dual specificity phosphatase 5 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of DUSP5 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818
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G |
Dusp6 |
dual specificity phosphatase 6 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of DUSP6 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185
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G |
Dync1li2 |
dynein, cytoplasmic 1 light intermediate chain 2 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of DYNC1LI2 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr19:531,783...554,670
Ensembl chr19:531,812...554,670
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G |
Dynll1 |
dynein light chain LC8-type 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of DYNLL1 mRNA |
CTD |
PMID:12154049 |
|
NCBI chr12:41,312,365...41,316,157
Ensembl chr12:41,312,367...41,314,741
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G |
Dyrk2 |
dual specificity tyrosine phosphorylation regulated kinase 2 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of DYRK2 mRNA |
CTD |
PMID:26865669 |
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NCBI chr 7:54,348,724...54,381,363
Ensembl chr 7:54,349,610...54,380,106
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G |
E2f1 |
E2F transcription factor 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with PX-866] results in decreased expression of E2F1 mRNA |
CTD |
PMID:26660119 |
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NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361
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G |
E2f2 |
E2F transcription factor 2 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of E2F2 mRNA |
CTD |
PMID:16497877 |
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NCBI chr 5:148,399,193...148,422,595
Ensembl chr 5:148,399,642...148,421,217
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G |
Eci1 |
enoyl-CoA delta isomerase 1 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of ECI1 mRNA |
CTD |
PMID:16079270 |
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NCBI chr10:13,456,715...13,470,061
Ensembl chr10:13,456,563...13,470,061
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G |
Edn3 |
endothelin 3 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of EDN3 mRNA ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of EDN3 mRNA] |
CTD |
PMID:14699072 |
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NCBI chr 3:163,562,307...163,586,636
Ensembl chr 3:163,562,520...163,585,093
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G |
Ednra |
endothelin receptor type A |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of EDNRA mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of EDNRA mRNA |
CTD |
PMID:19059307 |
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NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
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G |
Efemp1 |
EGF containing fibulin extracellular matrix protein 1 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of EFEMP1 mRNA Raloxifene Hydrochloride inhibits the reaction [Estradiol results in decreased expression of EFEMP1 mRNA] |
CTD |
PMID:14699072 PMID:21185374 |
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NCBI chr14:102,610,813...102,690,027
Ensembl chr14:102,610,908...102,690,018
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G |
Efna1 |
ephrin A1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of EFNA1 mRNA |
CTD |
PMID:26865669 |
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NCBI chr 2:174,681,676...174,689,061
Ensembl chr 2:174,681,682...174,690,866
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G |
Egfr |
epidermal growth factor receptor |
multiple interactions increases phosphorylation decreases phosphorylation |
ISO EXP |
[Raloxifene Hydrochloride co-treated with epigallocatechin gallate] results in decreased phosphorylation of EGFR protein; Raloxifene Hydrochloride results in decreased expression of and affects the localization of EGFR protein Raloxifene Hydrochloride results in increased phosphorylation of EGFR protein Raloxifene Hydrochloride results in decreased phosphorylation of EGFR protein |
CTD |
PMID:18371987 PMID:23842642 PMID:24782323 |
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NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
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G |
Egln3 |
egl-9 family hypoxia-inducible factor 3 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of EGLN3 mRNA |
CTD |
PMID:16079270 |
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NCBI chr 6:71,650,297...71,675,766
Ensembl chr 6:71,650,297...71,675,766
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G |
Egr1 |
early growth response 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of EGR1 mRNA |
CTD |
PMID:19059307 |
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NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
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G |
Egr3 |
early growth response 3 |
multiple interactions decreases expression |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of EGR3 mRNA] Raloxifene Hydrochloride results in decreased expression of EGR3 mRNA |
CTD |
PMID:21185374 PMID:26865669 |
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NCBI chr15:45,150,335...45,156,052
Ensembl chr15:45,150,567...45,154,627
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G |
Eif1 |
eukaryotic translation initiation factor 1 |
multiple interactions increases expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of EIF1 mRNA Raloxifene Hydrochloride results in increased expression of EIF1 mRNA |
CTD |
PMID:16497877 PMID:19059307 |
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NCBI chr10:85,246,751...85,248,842
Ensembl chr10:85,246,764...85,427,327 Ensembl chr 5:85,246,764...85,427,327
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G |
Eif2s1 |
eukaryotic translation initiation factor 2 subunit alpha |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of EIF2S1 mRNA |
CTD |
PMID:16514628 |
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NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
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G |
Eif5 |
eukaryotic translation initiation factor 5 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of EIF5 mRNA |
CTD |
PMID:16514628 |
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NCBI chr 6:130,589,162...130,597,656
Ensembl chr 6:130,589,143...130,597,656
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G |
Eif5a |
eukaryotic translation initiation factor 5A |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of EIF5A mRNA |
CTD |
PMID:16497877 |
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NCBI chr10:54,640,104...54,644,845
Ensembl chr10:54,640,024...54,644,656
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G |
Elf3 |
E74 like ETS transcription factor 3 |
multiple interactions increases expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ELF3 mRNA Raloxifene Hydrochloride results in increased expression of ELF3 mRNA |
CTD |
PMID:16202921 PMID:19059307 |
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NCBI chr13:46,690,460...46,695,394
Ensembl chr13:46,690,466...46,695,481
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G |
Ell |
elongation factor for RNA polymerase II |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of ELL mRNA |
CTD |
PMID:15849065 |
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NCBI chr16:18,843,775...18,891,484
Ensembl chr16:18,843,780...18,891,118
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G |
Elob |
elongin B |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of ELOB mRNA |
CTD |
PMID:16514628 |
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NCBI chr10:12,848,830...12,853,897
Ensembl chr10:12,848,827...12,853,635
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G |
Elovl5 |
ELOVL fatty acid elongase 5 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of ELOVL5 mRNA |
CTD |
PMID:16514628 |
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NCBI chr 8:78,790,846...78,857,307
Ensembl chr 8:78,790,846...78,857,284
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G |
Emp1 |
epithelial membrane protein 1 |
multiple interactions |
ISO |
ESR1 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of EMP1 mRNA] |
CTD |
PMID:14699072 |
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NCBI chr 4:168,212,901...168,233,039
Ensembl chr 4:168,212,861...168,232,904
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G |
Enc1 |
ectodermal-neural cortex 1 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of ENC1 mRNA [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of ENC1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ENC1 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr 2:28,550,670...28,562,591
Ensembl chr 2:28,550,464...28,562,713
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G |
Endod1 |
endonuclease domain containing 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ENDOD1 mRNA |
CTD |
PMID:19059307 |
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NCBI chr 8:11,209,113...11,238,507
Ensembl chr 8:11,211,110...11,238,892
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G |
Eng |
endoglin |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of ENG mRNA; Raloxifene Hydrochloride results in increased expression of ENG protein |
CTD |
PMID:20135064 PMID:32947957 |
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NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230
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G |
Eno2 |
enolase 2 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ENO2 mRNA |
CTD |
PMID:14699072 |
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NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980
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G |
Enpp2 |
ectonucleotide pyrophosphatase/phosphodiesterase 2 |
multiple interactions affects expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of ENPP2 mRNA Raloxifene Hydrochloride affects the expression of ENPP2 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827
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G |
Entpd2 |
ectonucleoside triphosphate diphosphohydrolase 2 |
increases expression |
EXP |
Raloxifene Hydrochloride results in increased expression of ENTPD2 mRNA |
CTD |
PMID:15576828 |
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NCBI chr 3:8,213,575...8,219,094
Ensembl chr 3:8,213,663...8,226,866
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G |
Epcam |
epithelial cell adhesion molecule |
multiple interactions |
ISO |
[APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of EPCAM mRNA; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of EPCAM protein |
CTD |
PMID:24431404 |
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NCBI chr 6:6,880,142...6,896,103
Ensembl chr 6:6,878,237...6,896,127
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G |
Epha1 |
Eph receptor A1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of EPHA1 mRNA |
CTD |
PMID:12154049 |
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NCBI chr 4:71,246,409...71,260,920
Ensembl chr 4:71,246,409...71,260,846
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G |
Epha4 |
Eph receptor A4 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of EPHA4 mRNA |
CTD |
PMID:26865669 |
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NCBI chr 9:78,815,460...78,958,139
Ensembl chr 9:78,815,460...78,958,139
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G |
Epor |
erythropoietin receptor |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of EPOR mRNA |
CTD |
PMID:14699072 |
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NCBI chr 8:20,489,678...20,494,257
Ensembl chr 8:20,489,678...20,494,257
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G |
Erbb2 |
erb-b2 receptor tyrosine kinase 2 |
decreases response to substance |
ISO |
ERBB2 protein results in decreased susceptibility to Raloxifene Hydrochloride |
CTD |
PMID:16609042 |
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NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
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G |
Erbb3 |
erb-b2 receptor tyrosine kinase 3 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ERBB3 mRNA |
CTD |
PMID:14699072 |
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NCBI chr 7:994,549...1,015,876
Ensembl chr 7:996,225...1,015,525
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G |
Erbb4 |
erb-b2 receptor tyrosine kinase 4 |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in decreased expression of ERBB4 mRNA] |
CTD |
PMID:21185374 |
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NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595
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G |
Esr1 |
estrogen receptor 1 |
affects response to substance increases response to substance multiple interactions affects folding affects binding decreases activity decreases expression increases expression affects expression |
ISO EXP |
ESR1 gene polymorphism affects the susceptibility to Raloxifene Hydrochloride ESR1 exon polymorphism results in increased susceptibility to Raloxifene Hydrochloride [ESR1 protein co-treated with ESR2 protein] affects the reaction [Raloxifene Hydrochloride results in increased cleavage of PARP1 protein]; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of ANKRD28 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of CCN3 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of CSF2 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of ENC1 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of HAS2 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of KCNN4 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of LINC00312 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of LMCD1 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of PLAU mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of RGS16 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of SLN mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of TGFBI mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of TNFRSF11B mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of TXNIP mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of CA12 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of CRISPLD2 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of EDNRA mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of EIF1 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of ENPP2 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of FHL2 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of G0S2 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of GRK5 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of HEG1 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of HK1 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of IDH2 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of ISG20 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of KCTD12 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of KLRC2 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of LPL mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of MSMB mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of NLRP3 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of NPR2 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of OSBPL3 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of PFKFB3 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of PTPRE mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of RASGRP1 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of RET mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of RGS4 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of RHOBTB3 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of RIPOR2 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of SEMA3B mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of SGK1 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of SYBU mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of TIPARP mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of TMOD1 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of TMPRSS3 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of ZNF395 mRNA; ARID5A protein inhibits the reaction [Raloxifene Hydrochloride results in increased activity of ESR1 protein]; ESR1 protein affects the reaction [Raloxifene Hydrochloride affects the localization of FOXO3 protein]; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of EMP1 mRNA]; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of HSPA1B mRNA]; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of MFAP5 mRNA]; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in decreased secretion of IL6 protein]; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of IDH2 mRNA]; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of KLRC2 mRNA]; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of KLRC3 mRNA]; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of PLPP3 mRNA]; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of TGFB3 mRNA]; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of ZFP36 mRNA]; ESR1 protein promotes the reaction [Raloxifene Hydrochloride results in increased activity of TERT protein]; Raloxifene Hydrochloride affects the folding of and affects the activity of ESR1 protein; Raloxifene Hydrochloride binds to and affects the activity of ESR1 protein; Raloxifene Hydrochloride binds to and results in decreased activity of ESR1 protein; Raloxifene Hydrochloride inhibits the reaction [ESR1 protein binds to CCL3 promoter]; Raloxifene Hydrochloride inhibits the reaction [ESR1 protein binds to RELA protein]; Raloxifene Hydrochloride inhibits the reaction [Estradiol binds to ESR1 protein]; Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of ESR1 protein]; Raloxifene Hydrochloride inhibits the reaction [trichostatin A results in decreased expression of ESR1 mRNA]; Raloxifene Hydrochloride promotes the reaction [ESR1 protein binds to IGF1 promoter]; Raloxifene Hydrochloride promotes the reaction [ESR1 protein binds to KLRC3 gene]; Raloxifene Hydrochloride promotes the reaction [ESR1 protein binds to PTGS2 promoter]; Raloxifene Hydrochloride results in increased activity of and affects the localization of ESR1 protein Raloxifene Hydrochloride affects the folding of ESR1 protein [Raloxifene Hydrochloride binds to ESR1 protein] which binds to SERPINB9 protein; [Raloxifene Hydrochloride binds to ESR1 protein] which binds to TFF1 protein; Raloxifene Hydrochloride binds to ESR1 protein Raloxifene Hydrochloride results in decreased activity of ESR1 protein Raloxifene Hydrochloride results in decreased expression of ESR1 mRNA; Raloxifene Hydrochloride results in decreased expression of ESR1 protein Raloxifene Hydrochloride results in increased expression of ESR1 mRNA; Raloxifene Hydrochloride results in increased expression of ESR1 protein ESR1 protein promotes the reaction [Raloxifene Hydrochloride results in increased expression of SLC1A2 mRNA]; ESR1 protein promotes the reaction [Raloxifene Hydrochloride results in increased expression of SLC1A3 mRNA] Raloxifene Hydrochloride metabolite binds to ESR1 protein Raloxifene Hydrochloride affects the expression of ESR1 mRNA [Raloxifene Hydrochloride co-treated with Estradiol] results in decreased expression of ESR1 protein; [Raloxifene Hydrochloride co-treated with Oxygen deficiency] results in increased expression of ESR1 protein; Raloxifene Hydrochloride affects the reaction [Oxygen deficiency affects the expression of ESR1 protein alternative form]; Raloxifene Hydrochloride binds to and affects the folding of ESR1 protein mutant form; Raloxifene Hydrochloride inhibits the reaction [Oxygen deficiency results in decreased expression of ESR1 mRNA] |
CTD |
PMID:9751507 PMID:11535548 PMID:11867264 PMID:14617632 PMID:14699072 PMID:15161930 PMID:15521089 PMID:15807179 PMID:15842231 PMID:15941852 PMID:15961563 PMID:16497877 PMID:16604479 PMID:16790557 PMID:16798746 PMID:17203231 PMID:17299137 PMID:17350824 PMID:17395694 PMID:17654759 PMID:17872375 PMID:18976723 PMID:19059307 PMID:19350480 PMID:19432593 PMID:20362049 PMID:20435135 PMID:21256200 PMID:21543282 PMID:22476901 PMID:22965848 PMID:24782323 PMID:24846829 PMID:25012808 PMID:25571714 PMID:26470790 PMID:26865669 PMID:26879975 PMID:27163517 PMID:27576059 PMID:27721470 PMID:28859903 More...
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NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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G |
Esr2 |
estrogen receptor 2 |
multiple interactions increases response to substance decreases activity increases activity affects expression increases expression |
ISO EXP |
[ESR1 protein co-treated with ESR2 protein] affects the reaction [Raloxifene Hydrochloride results in increased cleavage of PARP1 protein]; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ABCC1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ACKR3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ACSL1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of AGO2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of AKAP1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ARL4C mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ASB13 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of C14ORF132 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of C2CD2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CA12 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CALM1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CASKIN2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CASP7 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CCND1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CDK5R1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CEBPB mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CERS6 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CLCN4 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CRISPLD2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CSDC2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CUEDC1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CYP19A1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CYP24A1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CYP26B1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of DOCK9 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of EDNRA mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ELF3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ENDOD1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of EVI2A mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FADD mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FGD6 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FGFR2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FHL2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FLNB mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FOSL2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FOXO1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FST mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of GPRC5C mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HEG1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HK1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HMOX1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HPCAL1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HSPB8 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HTR3A mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of INPP5A mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of IVL mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of KAZN mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of KCTD12 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of KIF3C mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of KLRC3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of KLRK1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of LBH mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of LMNB2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of LRIG1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of LRRC20 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of LYSMD4 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MAFF mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MAGEA8 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MAP3K5 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MAP3K8 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MAPKAPK2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MBNL2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MDFIC mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MEF2A mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MMP12 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MN1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MPPED2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MYT1L mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NAV2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NCF2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NCOA1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NCOA4 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NDRG4 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NFATC1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NFIL3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NFKBIA mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NINJ1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NPR2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NR1D1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NR2F6 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NUAK1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of OSBPL3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of OTUB2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PCTP mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PDLIM3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PHC2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PHF11 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PITPNC1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PRKCZ mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PTGER3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PTGES mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of RCOR3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of RET mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of RETREG1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of RFTN1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of RGL1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of RHOF mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of RPS6KA2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SALL1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SCNN1A mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SEMA3F mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SERPINB6 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SLC18A3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SREBF1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SSH1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ST3GAL1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of STK24 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SYBU mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SYNJ2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SYNPO mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of TACC1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of TACC2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of TBXA2R mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of TGFA mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of TMOD1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of TNS3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of TOB1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of TRAF3IP2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of UPF1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of WNT5A mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ZCCHC24 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ZMIZ1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ZNF395 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ADAM19 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ADORA2B mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of AMIGO2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ANKRD1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of AREG mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ATF3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of BIRC3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CCL2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CCL20 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CDH2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CDO1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CXCL12 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CXCL8 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of DACT1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of DCBLD2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of DUSP2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of DUSP5 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of EGR1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ENC1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of FUT9 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of GAD1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of GRB10 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of GYG1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of HBEGF mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ID4 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of IFNGR2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of INHBA mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of JAG1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of KRT17 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of KRT34 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of LDLRAD4 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of LMCD1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of MAP2K3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of NAB1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of NFKBIE mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of NR3C1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of NR4A3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of OCLN mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of PCDH7 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of PDP1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of PTGS2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of PTP4A3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of PTX3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of RASGRP1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of RCAN2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of RFK mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of RGS4 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of RRAD mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of SERPINE1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of SLCO4C1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of SOD2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TCIM mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TGFB2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TGFBI mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TMEM158 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TNC mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TNFRSF11B mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TNFRSF21 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TNIK mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TRAF5 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TRIB1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TRIM36 mRNA; [trichostatin A co-treated with Estradiol co-treated with Raloxifene Hydrochloride] results in increased expression of ESR2 protein; [trichostatin A co-treated with Raloxifene Hydrochloride] results in increased expression of ESR2 mRNA; [trichostatin A co-treated with Raloxifene Hydrochloride] results in increased expression of ESR2 protein; ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of EDN3 mRNA]; ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of FLNB mRNA]; ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of IER3 mRNA]; ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of KLRC2 mRNA]; ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of MSMB mRNA]; ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of NCF2 mRNA]; ESR2 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of GABRR1 mRNA]; ESR2 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of TMT1A mRNA]; ESR2 protein promotes the reaction [Raloxifene Hydrochloride results in increased activity of TERT protein]; Raloxifene Hydrochloride binds to and results in increased activity of ESR2 protein; Raloxifene Hydrochloride inhibits the reaction [3,3'-diindolylmethane results in increased expression of ESR2 mRNA]; Raloxifene Hydrochloride promotes the reaction [[trichostatin A co-treated with Estradiol] results in increased expression of ESR2 mRNA]; Raloxifene Hydrochloride promotes the reaction [ESR2 protein binds to ESR2 protein]; Raloxifene Hydrochloride promotes the reaction [ESR2 protein binds to IGF1 promoter]; Raloxifene Hydrochloride promotes the reaction [ESR2 protein binds to PTGS2 promoter] ESR2 protein results in increased susceptibility to Raloxifene Hydrochloride Raloxifene Hydrochloride results in decreased activity of ESR2 protein Raloxifene Hydrochloride results in increased activity of ESR2 protein [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of ESR2 protein; ESR2 protein affects the reaction [Raloxifene Hydrochloride inhibits the reaction [Streptozocin results in decreased secretion of MMP2 protein]]; Raloxifene Hydrochloride binds to and affects the activity of ESR2 protein alternative form; Raloxifene Hydrochloride inhibits the reaction [Oxygen deficiency results in increased expression of ESR2 mRNA]; Raloxifene Hydrochloride inhibits the reaction [Oxygen deficiency results in increased expression of ESR2 protein] [Raloxifene Hydrochloride co-treated with Bexarotene] affects the reaction [Azoxymethane affects the expression of ESR2 mRNA]; [Raloxifene Hydrochloride co-treated with Bexarotene] affects the reaction [Azoxymethane affects the expression of ESR2 protein]; ESR2 protein promotes the reaction [Raloxifene Hydrochloride results in increased expression of SLC1A2 mRNA]; ESR2 protein promotes the reaction [Raloxifene Hydrochloride results in increased expression of SLC1A3 mRNA]; Raloxifene Hydrochloride affects the reaction [Azoxymethane affects the expression of ESR2 mRNA]; Raloxifene Hydrochloride affects the reaction [Azoxymethane affects the expression of ESR2 protein] Raloxifene Hydrochloride affects the expression of ESR2 mRNA Raloxifene Hydrochloride results in increased expression of ESR2 protein |
CTD |
PMID:14699072 PMID:15924412 PMID:16798746 PMID:17638070 PMID:17654759 PMID:17872375 PMID:17962382 PMID:19059307 PMID:19350480 PMID:20160136 PMID:22398780 PMID:22476901 PMID:22965848 PMID:23471663 PMID:24080207 PMID:24431404 PMID:24782323 PMID:24846829 PMID:36513145 More...
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NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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G |
Evi2a |
ecotropic viral integration site 2A |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of EVI2A mRNA |
CTD |
PMID:19059307 |
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NCBI chr10:64,485,760...64,489,660
Ensembl chr10:64,485,200...64,489,843
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G |
F11 |
coagulation factor XI |
increases activity |
ISO |
Raloxifene Hydrochloride results in increased activity of F11 protein |
CTD |
PMID:16359964 |
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NCBI chr16:46,987,988...47,009,015
Ensembl chr16:46,986,107...47,008,437
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G |
F12 |
coagulation factor XII |
increases activity |
ISO |
Raloxifene Hydrochloride results in increased activity of F12 protein |
CTD |
PMID:16359964 |
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NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530
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G |
F13a1 |
coagulation factor XIII A1 chain |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of F13A1 mRNA |
CTD |
PMID:14699072 |
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NCBI chr17:27,815,723...27,992,494
Ensembl chr17:27,815,702...27,992,700
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G |
F2r |
coagulation factor II (thrombin) receptor |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of F2R mRNA |
CTD |
PMID:12154049 |
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NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870
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G |
F8 |
coagulation factor VIII |
increases activity increases expression |
ISO |
Raloxifene Hydrochloride results in increased activity of F8 protein Raloxifene Hydrochloride results in increased expression of F8 protein |
CTD |
PMID:15850603 PMID:16359964 |
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NCBI chr18:140,848...172,330
Ensembl chr18:140,955...171,857
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G |
Fabp4 |
fatty acid binding protein 4 |
increases expression multiple interactions |
ISO |
Raloxifene Hydrochloride results in increased expression of FABP4 mRNA Raloxifene Hydrochloride affects the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of FABP4 protein] |
CTD |
PMID:16643890 PMID:31470850 |
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NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578
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G |
Fadd |
Fas associated via death domain |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FADD mRNA |
CTD |
PMID:19059307 |
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NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
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G |
Fam171b |
family with sequence similarity 171, member B |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with Estradiol] results in increased expression of FAM171B mRNA |
CTD |
PMID:21185374 |
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NCBI chr 3:68,930,755...68,986,113
Ensembl chr 3:68,930,822...68,986,127
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G |
Fap |
fibroblast activation protein, alpha |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of FAP mRNA |
CTD |
PMID:14699072 |
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NCBI chr 3:47,138,823...47,207,671
Ensembl chr 3:47,138,813...47,225,545
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G |
Fgd6 |
FYVE, RhoGEF and PH domain containing 6 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FGD6 mRNA |
CTD |
PMID:19059307 |
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NCBI chr 7:28,597,609...28,712,908
Ensembl chr 7:28,597,609...28,712,456
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G |
Fgf8 |
fibroblast growth factor 8 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of FGF8 mRNA |
CTD |
PMID:29990529 |
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NCBI chr 1:244,584,477...244,590,578
Ensembl chr 1:244,584,652...244,590,359
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G |
Fgf9 |
fibroblast growth factor 9 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of FGF9 mRNA |
CTD |
PMID:16079270 |
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NCBI chr15:32,208,993...32,254,952
Ensembl chr15:32,210,074...32,253,309
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G |
Fgfr2 |
fibroblast growth factor receptor 2 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FGFR2 mRNA |
CTD |
PMID:19059307 |
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NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626
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G |
Fhl1 |
four and a half LIM domains 1 |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of FHL1 mRNA] |
CTD |
PMID:21185374 |
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NCBI chr X:134,555,399...134,614,930
Ensembl chr X:134,555,479...134,614,928
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G |
Fhl2 |
four and a half LIM domains 2 |
multiple interactions affects expression decreases expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of FHL2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FHL2 mRNA Raloxifene Hydrochloride affects the expression of FHL2 mRNA Raloxifene Hydrochloride results in decreased expression of FHL2 mRNA |
CTD |
PMID:14699072 PMID:19059307 PMID:26865669 |
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NCBI chr 9:45,388,979...45,462,421
Ensembl chr 9:45,388,981...45,431,192
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G |
Fis1 |
fission, mitochondrial 1 |
affects expression increases expression |
EXP |
Raloxifene Hydrochloride affects the expression of FIS1 mRNA Raloxifene Hydrochloride results in increased expression of FIS1 mRNA |
CTD |
PMID:15576828 PMID:16079270 |
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NCBI chr12:19,708,560...19,723,392
Ensembl chr12:19,708,558...19,723,377
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G |
Fkbp3 |
FKBP prolyl isomerase 3 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of FKBP3 mRNA |
CTD |
PMID:16079270 |
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NCBI chr 6:83,113,885...83,125,500
Ensembl chr 6:83,113,786...83,127,011
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G |
Fkbp5 |
FKBP prolyl isomerase 5 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of FKBP5 mRNA |
CTD |
PMID:22217510 |
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NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674
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G |
Flnb |
filamin B |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of FLNB mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FLNB mRNA; ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of FLNB mRNA] |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr15:16,961,999...17,095,059
Ensembl chr15:16,962,003...17,095,006
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G |
Flnc |
filamin C |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of FLNC mRNA |
CTD |
PMID:16514628 |
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NCBI chr 4:58,034,088...58,061,882
Ensembl chr 4:58,034,189...58,061,844
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G |
Flrt1 |
fibronectin leucine rich transmembrane protein 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of FLRT1 mRNA |
CTD |
PMID:14699072 |
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NCBI chr 1:204,275,785...204,292,844
Ensembl chr 1:204,275,367...204,353,750
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G |
Fmnl1 |
formin-like 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of FMNL1 mRNA |
CTD |
PMID:14699072 |
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NCBI chr10:88,115,876...88,143,342
Ensembl chr10:88,116,009...88,143,357
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G |
Fn1 |
fibronectin 1 |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [TGFB1 protein results in increased expression of FN1 mRNA] |
CTD |
PMID:15920148 |
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NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
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G |
Fosl2 |
FOS like 2, AP-1 transcription factor subunit |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FOSL2 mRNA |
CTD |
PMID:19059307 |
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NCBI chr 6:24,297,898...24,319,219
Ensembl chr 6:24,300,956...24,320,034
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G |
Foxa2 |
forkhead box A2 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of FOXA2 mRNA |
CTD |
PMID:23184660 |
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NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326
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G |
Foxc1 |
forkhead box C1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of FOXC1 mRNA |
CTD |
PMID:26865669 |
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NCBI chr17:32,631,379...32,635,361
Ensembl chr17:32,633,142...32,634,803
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G |
Foxe1 |
forkhead box E1 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of FOXE1 mRNA |
CTD |
PMID:16079270 |
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NCBI chr 5:60,630,027...60,632,835
Ensembl chr 5:60,630,027...60,632,835
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G |
Foxo1 |
forkhead box O1 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of FOXO1 mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FOXO1 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
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G |
Foxo3 |
forkhead box O3 |
affects localization multiple interactions |
ISO |
Raloxifene Hydrochloride affects the localization of FOXO3 protein ESR1 protein affects the reaction [Raloxifene Hydrochloride affects the localization of FOXO3 protein]; GPER1 protein affects the reaction [Raloxifene Hydrochloride affects the localization of FOXO3 protein] |
CTD |
PMID:26470790 |
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NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
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G |
Fst |
follistatin |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of FST mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FST mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr 2:46,123,260...46,130,584
Ensembl chr 2:46,123,439...46,130,571
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G |
Fut9 |
fucosyltransferase 9 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of FUT9 mRNA |
CTD |
PMID:19059307 |
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NCBI chr 5:39,351,815...39,565,256
Ensembl chr 5:39,351,819...39,565,130
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G |
Fyttd1 |
forty-two-three domain containing 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of FYTTD1 mRNA |
CTD |
PMID:16514628 |
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NCBI chr11:67,877,967...67,907,500
Ensembl chr11:67,877,967...67,907,511
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G |
Fzd6 |
frizzled class receptor 6 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of FZD6 mRNA |
CTD |
PMID:14699072 |
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NCBI chr 7:70,055,012...70,086,781
Ensembl chr 7:70,055,068...70,086,776
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G |
G0s2 |
G0/G1switch 2 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of G0S2 mRNA |
CTD |
PMID:19059307 |
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NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451
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G |
Gabarap |
GABA type A receptor-associated protein |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of GABARAP mRNA |
CTD |
PMID:16079270 |
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NCBI chr10:54,714,777...54,718,099
Ensembl chr10:54,714,198...54,717,765
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G |
Gabbr2 |
gamma-aminobutyric acid type B receptor subunit 2 |
multiple interactions |
ISO |
Raloxifene Hydrochloride promotes the reaction [Estradiol results in increased expression of GABBR2 mRNA] |
CTD |
PMID:21185374 |
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NCBI chr 5:60,947,517...61,288,104
Ensembl chr 5:60,947,526...61,288,104
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G |
Gabpa |
GA binding protein transcription factor subunit alpha |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of GABPA mRNA |
CTD |
PMID:12154049 |
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NCBI chr11:23,888,586...23,917,612
Ensembl chr11:23,888,815...23,917,605
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G |
Gabrg1 |
gamma-aminobutyric acid type A receptor subunit gamma 1 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of GABRG1 mRNA |
CTD |
PMID:16079270 |
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NCBI chr14:37,396,217...37,469,606
Ensembl chr14:37,396,294...37,635,956
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G |
Gabrr1 |
gamma-aminobutyric acid type A receptor subunit rho 1 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of GABRR1 mRNA ESR2 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of GABRR1 mRNA] |
CTD |
PMID:14699072 |
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NCBI chr 5:47,524,151...47,561,228
Ensembl chr 5:47,524,151...47,561,228
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G |
Gad1 |
glutamate decarboxylase 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of GAD1 mRNA |
CTD |
PMID:19059307 |
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NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333
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G |
Gal |
galanin and GMAP prepropeptide |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of GAL mRNA |
CTD |
PMID:16202921 |
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NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959
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G |
Gas6 |
growth arrest specific 6 |
increases expression multiple interactions affects expression |
ISO EXP |
Raloxifene Hydrochloride results in increased expression of GAS6 mRNA fulvestrant inhibits the reaction [Raloxifene Hydrochloride results in increased expression of GAS6 mRNA] Raloxifene Hydrochloride affects the expression of GAS6 mRNA |
CTD |
PMID:16079270 PMID:19429434 |
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NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904
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G |
Gata2 |
GATA binding protein 2 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of GATA2 mRNA |
CTD |
PMID:19429434 |
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NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761
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G |
Gcnt1 |
glucosaminyl (N-acetyl) transferase 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of GCNT1 mRNA |
CTD |
PMID:14699072 |
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NCBI chr 1:214,718,344...214,755,735
Ensembl chr 1:214,718,293...214,758,776
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G |
Gdf9 |
growth differentiation factor 9 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of GDF9 mRNA |
CTD |
PMID:22841776 |
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NCBI chr10:37,589,200...37,599,970
Ensembl chr10:37,595,679...37,599,672
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G |
Gfra2 |
GDNF family receptor alpha 2 |
increases expression |
EXP |
Raloxifene Hydrochloride results in increased expression of GFRA2 mRNA |
CTD |
PMID:15576828 |
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NCBI chr15:45,941,841...46,033,715
Ensembl chr15:45,941,828...46,033,714
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G |
Gh1 |
growth hormone 1 |
multiple interactions |
ISO |
Raloxifene Hydrochloride promotes the reaction [GH1 protein results in increased phosphorylation of JAK2 protein] |
CTD |
PMID:17272397 |
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NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078
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G |
Ghr |
growth hormone receptor |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of GHR mRNA |
CTD |
PMID:16202921 |
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NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735
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G |
Ghrh |
growth hormone releasing hormone |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of GHRH mRNA |
CTD |
PMID:16079270 |
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NCBI chr 3:145,992,762...146,012,528
Ensembl chr 3:145,992,763...146,011,889
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G |
Ghrhr |
growth hormone releasing hormone receptor |
affects expression affects response to substance |
EXP ISO |
Raloxifene Hydrochloride affects the expression of GHRHR mRNA GHRHR affects the susceptibility to Raloxifene Hydrochloride |
CTD |
PMID:16079270 PMID:32934756 |
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NCBI chr 4:84,498,159...84,532,851
Ensembl chr 4:84,500,212...84,532,776
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G |
Gjb2 |
gap junction protein, beta 2 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of GJB2 mRNA |
CTD |
PMID:12370124 |
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NCBI chr15:31,260,390...31,278,222
Ensembl chr15:31,260,357...31,278,177
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G |
Glrb |
glycine receptor, beta |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of GLRB mRNA |
CTD |
PMID:14699072 |
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NCBI chr 2:166,134,616...166,207,498
Ensembl chr 2:166,134,626...166,207,489
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G |
Glrx |
glutaredoxin |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of GLRX mRNA |
CTD |
PMID:14699072 |
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NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680
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G |
Glul |
glutamate-ammonia ligase |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of GLUL mRNA |
CTD |
PMID:16079270 |
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NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108
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G |
Glyat |
glycine-N-acyltransferase |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of GLYAT mRNA |
CTD |
PMID:14699072 |
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NCBI chr 1:209,704,213...209,724,949
Ensembl chr 1:209,704,268...209,724,942
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G |
Gnb1 |
G protein subunit beta 1 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of GNB1 mRNA |
CTD |
PMID:16079270 |
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NCBI chr 5:166,075,508...166,142,223
Ensembl chr 5:166,075,629...166,142,124
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G |
Gnb4 |
G protein subunit beta 4 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of GNB4 mRNA |
CTD |
PMID:19429434 |
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NCBI chr 2:115,360,746...115,400,680
Ensembl chr 2:115,364,918...115,400,579
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G |
Gnrh1 |
gonadotropin releasing hormone 1 |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol promotes the reaction [GNRH1 protein results in increased secretion of PRL protein]] |
CTD |
PMID:17054466 |
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NCBI chr15:41,972,482...41,976,690
Ensembl chr15:41,972,905...41,973,581 Ensembl chr15:41,972,905...41,973,581
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G |
Golga5 |
golgin A5 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of GOLGA5 mRNA |
CTD |
PMID:16514628 |
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NCBI chr 6:121,612,389...121,640,552
Ensembl chr 6:121,612,529...121,640,413
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G |
Gpc1 |
glypican 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of GPC1 mRNA |
CTD |
PMID:14699072 |
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NCBI chr 9:93,396,234...93,424,047
Ensembl chr 9:93,396,234...93,424,047
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G |
Gpc3 |
glypican 3 |
increases expression |
EXP |
Raloxifene Hydrochloride results in increased expression of GPC3 mRNA |
CTD |
PMID:15576828 |
|
NCBI chr X:131,868,986...132,236,824
Ensembl chr X:131,868,990...132,236,798
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G |
Gper1 |
G protein-coupled estrogen receptor 1 |
multiple interactions increases activity |
EXP ISO |
[4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline binds to and results in decreased activity of GPER1 protein] inhibits the reaction [[Raloxifene Hydrochloride results in increased activity of GPER1 protein] which results in increased expression of SLC1A2 protein]; [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline results in decreased activity of GPER1 protein] inhibits the reaction [[Raloxifene Hydrochloride results in increased activity of GPER1 protein] which results in increased expression of SLC1A3 protein]; [Raloxifene Hydrochloride results in increased activity of GPER1 protein] which results in increased expression of SLC1A2 protein; [Raloxifene Hydrochloride results in increased activity of GPER1 protein] which results in increased expression of SLC1A3 protein GPER1 protein affects the reaction [Raloxifene Hydrochloride affects the localization of FOXO3 protein]; GPER1 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of AVP mRNA]; GPER1 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of MYC mRNA] Raloxifene Hydrochloride inhibits the reaction [Oxygen deficiency results in increased expression of GPER1 mRNA] |
CTD |
PMID:22453024 PMID:24782323 PMID:24846829 PMID:26200092 PMID:26470790 |
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NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889
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G |
Gpnmb |
glycoprotein nmb |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in decreased expression of GPNMB mRNA] |
CTD |
PMID:21185374 |
|
NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367
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G |
Gprc5c |
G protein-coupled receptor, class C, group 5, member C |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of GPRC5C mRNA |
CTD |
PMID:19059307 |
|
NCBI chr10:99,886,900...99,908,928
Ensembl chr10:99,887,077...99,908,926
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G |
Grb10 |
growth factor receptor bound protein 10 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of GRB10 mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of GRB10 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr14:86,495,051...86,602,800
Ensembl chr14:86,495,054...86,602,806
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G |
Greb1 |
growth regulating estrogen receptor binding 1 |
multiple interactions decreases expression |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of GREB1 mRNA] Raloxifene Hydrochloride results in decreased expression of GREB1 mRNA |
CTD |
PMID:21185374 PMID:26879975 |
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NCBI chr 6:39,440,522...39,562,364
Ensembl chr 6:39,440,504...39,581,633
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G |
Grhl1 |
grainyhead-like transcription factor 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of GRHL1 mRNA |
CTD |
PMID:19429434 |
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NCBI chr 6:41,207,325...41,257,516
Ensembl chr 6:41,207,348...41,254,301
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G |
Grina |
glutamate ionotropic receptor NMDA type subunit associated protein 1 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of GRINA mRNA |
CTD |
PMID:16079270 |
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NCBI chr 7:107,962,194...107,965,372
Ensembl chr 7:107,962,207...107,965,366
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G |
Grk5 |
G protein-coupled receptor kinase 5 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of GRK5 mRNA [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of GRK5 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr 1:260,028,269...260,223,699
Ensembl chr 1:260,028,242...260,218,701
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G |
Gyg1 |
glycogenin 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of GYG1 mRNA |
CTD |
PMID:19059307 |
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NCBI chr 2:102,611,888...102,653,916
Ensembl chr 2:102,598,496...102,653,797
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G |
H19 |
H19 imprinted maternally expressed transcript |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of H19 mRNA] |
CTD |
PMID:21185374 |
|
NCBI chr 1:197,730,698...197,733,374
Ensembl chr 1:197,730,698...197,733,134
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G |
Hal |
histidine ammonia lyase |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of HAL mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 7:28,007,449...28,037,701
Ensembl chr 7:28,006,972...28,037,701
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G |
Hapln1 |
hyaluronan and proteoglycan link protein 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of HAPLN1 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 2:20,631,640...20,696,388
Ensembl chr 2:20,631,640...20,693,777
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G |
Has2 |
hyaluronan synthase 2 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of HAS2 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 7:88,113,326...88,139,337
Ensembl chr 7:88,113,326...88,128,933
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G |
Hba-a1 |
hemoglobin alpha, adult chain 1 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of HBA-A1 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr10:15,337,265...15,338,121
Ensembl chr10:15,307,815...15,338,392
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G |
Hbegf |
heparin-binding EGF-like growth factor |
multiple interactions decreases expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of HBEGF mRNA; [Raloxifene Hydrochloride co-treated with PX-866] results in decreased expression of HBEGF mRNA Raloxifene Hydrochloride results in decreased expression of HBEGF mRNA |
CTD |
PMID:19059307 PMID:27017931 |
|
NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441
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G |
Hbg1 |
hemoglobin subunit gamma 1 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of HBG1 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 1:158,271,871...158,273,426
Ensembl chr 1:158,271,873...158,273,425
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G |
Hbp1 |
HMG-box transcription factor 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of HBP1 mRNA |
CTD |
PMID:16497877 |
|
NCBI chr 6:48,529,633...48,555,775
Ensembl chr 6:48,529,372...48,555,787
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G |
Heg1 |
heart development protein with EGF-like domains 1 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of HEG1 mRNA [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of HEG1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HEG1 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
|
NCBI chr11:67,006,954...67,095,020
Ensembl chr11:66,957,190...67,095,051
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G |
Herpud1 |
homocysteine inducible ER protein with ubiquitin like domain 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of HERPUD1 mRNA |
CTD |
PMID:16497877 |
|
NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424
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G |
Hey2 |
hes-related family bHLH transcription factor with YRPW motif 2 |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of HEY2 mRNA] |
CTD |
PMID:21185374 |
|
NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218
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G |
Hgf |
hepatocyte growth factor |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of HGF mRNA |
CTD |
PMID:16497877 |
|
NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
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G |
Hk1 |
hexokinase 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of HK1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HK1 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr20:30,230,488...30,332,099
Ensembl chr20:30,230,486...30,332,131
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G |
Hmcn1 |
hemicentin 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with Estradiol] results in increased expression of HMCN1 mRNA |
CTD |
PMID:21185374 |
|
NCBI chr13:62,615,461...63,084,524
Ensembl chr13:62,615,461...63,084,524
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G |
Hmga2 |
high mobility group AT-hook 2 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of HMGA2 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784
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G |
Hmgb1 |
high mobility group box 1 |
decreases expression affects expression |
ISO EXP |
Raloxifene Hydrochloride results in decreased expression of HMGB1 mRNA Raloxifene Hydrochloride affects the expression of HMGB1 mRNA |
CTD |
PMID:16079270 PMID:16514628 |
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NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565 Ensembl chr16:5,901,586...5,978,565
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G |
Hmox1 |
heme oxygenase 1 |
multiple interactions increases expression decreases expression affects expression |
ISO EXP |
1,10-phenanthroline inhibits the reaction [Raloxifene Hydrochloride results in increased expression of HMOX1 mRNA]; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HMOX1 mRNA; Allopurinol inhibits the reaction [Raloxifene Hydrochloride results in increased expression of HMOX1 mRNA]; Buthionine Sulfoximine promotes the reaction [Raloxifene Hydrochloride results in increased expression of HMOX1 mRNA]; Copper promotes the reaction [Raloxifene Hydrochloride results in increased expression of HMOX1 mRNA]; dimethyl sulfate inhibits the reaction [Raloxifene Hydrochloride results in increased expression of HMOX1 mRNA]; Glutathione inhibits the reaction [Raloxifene Hydrochloride results in increased expression of HMOX1 mRNA]; HMOX1 protein promotes the reaction [[Raloxifene Hydrochloride results in decreased expression of NOS2 protein] which results in decreased chemical synthesis of Nitric Oxide]; Iron promotes the reaction [Raloxifene Hydrochloride results in increased expression of HMOX1 mRNA]; MAP2K6 protein promotes the reaction [Raloxifene Hydrochloride results in increased expression of HMOX1 protein]; TEMPO inhibits the reaction [Raloxifene Hydrochloride results in increased expression of HMOX1 mRNA] Raloxifene Hydrochloride results in increased expression of HMOX1 mRNA; Raloxifene Hydrochloride results in increased expression of HMOX1 protein Raloxifene Hydrochloride results in decreased expression of HMOX1 mRNA Raloxifene Hydrochloride affects the expression of HMOX1 mRNA |
CTD |
PMID:16079270 PMID:16298037 PMID:19059307 PMID:20888885 |
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NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Hnf4a |
hepatocyte nuclear factor 4, alpha |
decreases expression multiple interactions |
ISO |
Raloxifene Hydrochloride results in decreased expression of HNF4A mRNA fulvestrant inhibits the reaction [Raloxifene Hydrochloride results in decreased expression of HNF4A mRNA] |
CTD |
PMID:23184660 |
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NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320
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G |
Hnrnpa2b1 |
heterogeneous nuclear ribonucleoprotein A2/B1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of HNRNPA2B1 mRNA |
CTD |
PMID:16514628 |
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NCBI chr 4:80,534,659...80,545,297
Ensembl chr 4:80,534,651...80,545,249
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G |
Hnrnph1 |
heterogeneous nuclear ribonucleoprotein H1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of HNRNPH1 mRNA |
CTD |
PMID:16514628 |
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NCBI chr10:34,692,868...34,702,849
Ensembl chr10:34,693,555...34,702,846
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G |
Hnrnpu |
heterogeneous nuclear ribonucleoprotein U |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of HNRNPU mRNA |
CTD |
PMID:16514628 |
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NCBI chr13:90,069,058...90,086,905
Ensembl chr13:90,074,181...90,086,588
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G |
Homer2 |
homer scaffold protein 2 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of HOMER2 mRNA |
CTD |
PMID:14699072 |
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NCBI chr 1:135,558,977...135,659,780
Ensembl chr 1:135,567,414...135,659,772
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G |
Hoxa1 |
homeobox A1 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of HOXA1 mRNA |
CTD |
PMID:16079270 |
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NCBI chr 4:81,255,814...81,258,587
Ensembl chr 4:81,255,883...81,258,504
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G |
Hpcal1 |
hippocalcin-like 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HPCAL1 mRNA |
CTD |
PMID:19059307 |
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NCBI chr 6:40,478,206...40,584,721
Ensembl chr 6:40,478,208...40,584,687
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G |
Hpgd |
15-hydroxyprostaglandin dehydrogenase |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of HPGD mRNA] |
CTD |
PMID:21185374 |
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NCBI chr16:33,986,265...34,024,228
Ensembl chr16:33,986,266...34,024,228
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G |
Hsd17b11 |
hydroxysteroid (17-beta) dehydrogenase 11 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with Estradiol] results in increased expression of HSD17B11 mRNA |
CTD |
PMID:21185374 |
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NCBI chr14:5,693,304...5,743,157
Ensembl chr14:5,711,964...5,743,161
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G |
Hsd17b4 |
hydroxysteroid (17-beta) dehydrogenase 4 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of HSD17B4 mRNA |
CTD |
PMID:16079270 |
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NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952
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G |
Hsp90ab1 |
heat shock protein 90 alpha family class B member 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of HSP90AB1 mRNA |
CTD |
PMID:16514628 |
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NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488
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G |
Hsp90b1 |
heat shock protein 90 beta family member 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of HSP90B1 mRNA |
CTD |
PMID:16514628 |
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NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788
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G |
Hspa1a |
heat shock protein family A (Hsp70) member 1A |
affects expression increases expression |
ISO EXP |
Raloxifene Hydrochloride affects the expression of HSPA1A mRNA Raloxifene Hydrochloride results in increased expression of HSPA1A protein |
CTD |
PMID:14699072 PMID:15860553 |
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NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227
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G |
Hspa1b |
heat shock protein family A (Hsp70) member 1B |
multiple interactions affects expression |
ISO |
ESR1 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of HSPA1B mRNA] Raloxifene Hydrochloride affects the expression of HSPA1B mRNA |
CTD |
PMID:14699072 |
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NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240 Ensembl chr20:3,856,006...3,873,240
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G |
Hspa4 |
heat shock protein family A (Hsp70) member 4 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of HSPA4 mRNA |
CTD |
PMID:16514628 |
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NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001
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G |
Hspa8 |
heat shock protein family A (Hsp70) member 8 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of HSPA8 mRNA |
CTD |
PMID:16514628 |
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NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
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G |
Hspb8 |
heat shock protein family B (small) member 8 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HSPB8 mRNA; Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of HSPB8 mRNA] |
CTD |
PMID:19059307 PMID:21185374 |
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NCBI chr12:40,176,405...40,205,002
Ensembl chr12:40,176,532...40,191,185
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G |
Hspd1 |
heat shock protein family D (Hsp60) member 1 |
decreases expression affects expression |
ISO EXP |
Raloxifene Hydrochloride results in decreased expression of HSPD1 mRNA Raloxifene Hydrochloride affects the expression of HSPD1 mRNA |
CTD |
PMID:16079270 PMID:16514628 |
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NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
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G |
Htr2a |
5-hydroxytryptamine receptor 2A |
affects expression multiple interactions |
ISO EXP |
Raloxifene Hydrochloride affects the expression of HTR2A mRNA Raloxifene Hydrochloride inhibits the reaction [estradiol 3-benzoate results in increased expression of HTR2A mRNA]; Raloxifene Hydrochloride inhibits the reaction [estradiol 3-benzoate results in increased expression of HTR2A protein] |
CTD |
PMID:14699072 PMID:17398000 |
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NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928
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G |
Htr3a |
5-hydroxytryptamine receptor 3A |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HTR3A mRNA |
CTD |
PMID:19059307 |
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NCBI chr 8:49,242,018...49,254,475
Ensembl chr 8:49,242,020...49,254,389
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G |
Htr5a |
5-hydroxytryptamine receptor 5A |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of HTR5A mRNA |
CTD |
PMID:16079270 |
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NCBI chr 4:7,444,968...7,454,651
Ensembl chr 4:7,444,968...7,454,651
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G |
Icam1 |
intercellular adhesion molecule 1 |
multiple interactions |
ISO |
Raloxifene Hydrochloride affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of ICAM1 protein] |
CTD |
PMID:32828944 |
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NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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G |
Id1 |
inhibitor of DNA binding 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ID1 mRNA |
CTD |
PMID:14699072 |
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NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
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G |
Id4 |
inhibitor of DNA binding 4 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ID4 mRNA |
CTD |
PMID:19059307 |
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NCBI chr17:16,389,387...16,391,956
Ensembl chr17:16,389,387...16,392,470
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G |
Idh2 |
isocitrate dehydrogenase (NADP(+)) 2 |
multiple interactions affects expression |
ISO EXP |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of IDH2 mRNA; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of IDH2 mRNA] Raloxifene Hydrochloride affects the expression of IDH2 mRNA |
CTD |
PMID:14699072 PMID:16079270 PMID:19059307 |
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NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
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G |
Ido1 |
indoleamine 2,3-dioxygenase 1 |
multiple interactions increases expression |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of IDO1 mRNA] Raloxifene Hydrochloride results in increased expression of IDO1 mRNA |
CTD |
PMID:18367319 |
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NCBI chr16:67,430,654...67,442,726
Ensembl chr16:67,430,578...67,442,730
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G |
Ier3 |
immediate early response 3 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of IER3 mRNA ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of IER3 mRNA] |
CTD |
PMID:14699072 |
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NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583
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G |
Ifit2 |
interferon-induced protein with tetratricopeptide repeats 2 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of IFIT2 mRNA |
CTD |
PMID:14699072 |
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NCBI chr 1:232,102,570...232,108,638
Ensembl chr 1:232,102,570...232,108,635
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G |
Ifngr2 |
interferon gamma receptor 2 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of IFNGR2 mRNA |
CTD |
PMID:19059307 |
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NCBI chr11:30,779,733...30,798,005
Ensembl chr11:30,779,733...30,798,005
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G |
Ifrd1 |
interferon-related developmental regulator 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of IFRD1 mRNA |
CTD |
PMID:16514628 |
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NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990
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G |
Igf1 |
insulin-like growth factor 1 |
multiple interactions decreases expression increases expression affects expression |
ISO EXP |
Raloxifene Hydrochloride inhibits the reaction [NCOR2 protein binds to IGF1 promoter]; Raloxifene Hydrochloride promotes the reaction [CREBBP protein binds to IGF1 promoter]; Raloxifene Hydrochloride promotes the reaction [ESR1 protein binds to IGF1 promoter]; Raloxifene Hydrochloride promotes the reaction [ESR2 protein binds to IGF1 promoter]; Raloxifene Hydrochloride promotes the reaction [NCOA1 protein binds to IGF1 promoter]; Raloxifene Hydrochloride promotes the reaction [NCOA2 protein binds to IGF1 promoter]; Raloxifene Hydrochloride promotes the reaction [NCOA3 protein binds to IGF1 promoter] Raloxifene Hydrochloride results in decreased expression of IGF1 mRNA; Raloxifene Hydrochloride results in decreased expression of IGF1 protein Raloxifene Hydrochloride results in increased expression of IGF1 mRNA Raloxifene Hydrochloride affects the expression of IGF1 mRNA |
CTD |
PMID:15762036 PMID:15978972 PMID:16912660 PMID:17645796 PMID:17872375 PMID:19350480 More...
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NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
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G |
Igf2 |
insulin-like growth factor 2 |
increases expression |
EXP |
Raloxifene Hydrochloride results in increased expression of IGF2 mRNA |
CTD |
PMID:15576828 |
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NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018
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G |
Igfbp3 |
insulin-like growth factor binding protein 3 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of IGFBP3 protein |
CTD |
PMID:15855258 PMID:16912660 |
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NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083
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G |
Igfbp4 |
insulin-like growth factor binding protein 4 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of IGFBP4 mRNA |
CTD |
PMID:14699072 |
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NCBI chr10:83,995,253...84,007,272
Ensembl chr10:83,989,591...84,007,225
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G |
Igfbp6 |
insulin-like growth factor binding protein 6 |
increases expression |
EXP |
Raloxifene Hydrochloride results in increased expression of IGFBP6 mRNA |
CTD |
PMID:15576828 |
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NCBI chr 7:133,276,309...133,280,944
Ensembl chr 7:133,276,234...133,280,966
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G |
Il10ra |
interleukin 10 receptor subunit alpha |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of IL10RA mRNA |
CTD |
PMID:16497877 |
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NCBI chr 8:45,563,009...45,578,041
Ensembl chr 8:45,563,137...45,578,061
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G |
Il11 |
interleukin 11 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with PX-866] results in decreased expression of IL11 mRNA |
CTD |
PMID:26660119 |
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NCBI chr 1:69,069,829...69,076,129
Ensembl chr 1:69,068,137...69,076,129
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G |
Il12a |
interleukin 12A |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of IL12A mRNA |
CTD |
PMID:19429434 |
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NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
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G |
Il13ra1 |
interleukin 13 receptor subunit alpha 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of IL13RA1 mRNA |
CTD |
PMID:22217510 |
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NCBI chr X:115,348,822...115,408,682
Ensembl chr X:115,348,860...115,408,681 Ensembl chr11:115,348,860...115,408,681
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G |
Il1b |
interleukin 1 beta |
multiple interactions |
ISO EXP |
[Raloxifene Hydrochloride co-treated with IL1B protein] results in increased expression of PTGDS mRNA; Fulvestrant inhibits the reaction [Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased expression of CCL20 protein]]; Fulvestrant inhibits the reaction [Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased phosphorylation of and affects the localization of RELA protein]]; Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased expression of BCL3 mRNA]; Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased expression of CCL20 protein]; Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased expression of CISH mRNA]; Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased expression of CXCL5 mRNA]; Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased expression of PLK3 mRNA]; Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased phosphorylation of and affects the localization of RELA protein] Fulvestrant inhibits the reaction [Raloxifene Hydrochloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of IL1B mRNA]]; Raloxifene Hydrochloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of IL1B mRNA]; Raloxifene Hydrochloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased secretion of IL1B protein] |
CTD |
PMID:12072388 PMID:24722370 PMID:25305410 |
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NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il1r1 |
interleukin 1 receptor type 1 |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in decreased expression of IL1R1 mRNA] |
CTD |
PMID:21185374 |
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NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937
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G |
Il1rap |
interleukin 1 receptor accessory protein |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of IL1RAP mRNA |
CTD |
PMID:14699072 |
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NCBI chr11:74,062,999...74,199,530
Ensembl chr11:74,070,304...74,199,530
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G |
Il4 |
interleukin 4 |
multiple interactions |
ISO EXP |
Raloxifene Hydrochloride inhibits the reaction [IL4 protein results in increased phosphorylation of STAT3 protein] [Raloxifene Hydrochloride co-treated with Bexarotene] affects the reaction [Azoxymethane affects the expression of IL4 mRNA] |
CTD |
PMID:24080207 PMID:24456369 |
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NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
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G |
Il4r |
interleukin 4 receptor |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of IL4R mRNA |
CTD |
PMID:14699072 |
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NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980
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G |
Il6 |
interleukin 6 |
decreases expression multiple interactions decreases secretion |
ISO EXP |
Raloxifene Hydrochloride results in decreased expression of IL6 mRNA; Raloxifene Hydrochloride results in decreased expression of IL6 protein Raloxifene Hydrochloride affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of IL6 protein]; Raloxifene Hydrochloride affects the reaction [[APOE protein affects the susceptibility to IL6 protein] which affects the phosphorylation of STAT3 protein]; Raloxifene Hydrochloride inhibits the reaction [IL6 protein results in increased phosphorylation of and affects the localization of STAT3 protein]; Raloxifene Hydrochloride inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]; Raloxifene Hydrochloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of IL6 mRNA]; Raloxifene Hydrochloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of IL6 protein]; Raloxifene Hydrochloride inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 mRNA]; Raloxifene Hydrochloride inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] Raloxifene Hydrochloride inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]; Raloxifene Hydrochloride inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] ESR1 protein affects the reaction [Raloxifene Hydrochloride results in decreased secretion of IL6 protein]; Raloxifene Hydrochloride inhibits the reaction [[IL6R protein co-treated with IL6 protein] results in increased phosphorylation of STAT3 protein]; Raloxifene Hydrochloride inhibits the reaction [IL6 protein results in increased phosphorylation of and affects the localization of STAT3 protein]; Raloxifene Hydrochloride inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]; Raloxifene Hydrochloride inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] |
CTD |
PMID:15579764 PMID:15762036 PMID:15953991 PMID:16298037 PMID:19533603 PMID:27576059 PMID:28430601 PMID:28711499 PMID:32828944 PMID:32940862 PMID:32947957 More...
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Il6r |
interleukin 6 receptor |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [[IL6R protein co-treated with IL6 protein] results in increased phosphorylation of STAT3 protein] |
CTD |
PMID:32828944 |
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NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536
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G |
Il6st |
interleukin 6 cytokine family signal transducer |
affects binding |
ISO |
Raloxifene Hydrochloride binds to IL6ST protein |
CTD |
PMID:24456369 PMID:32940862 |
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NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936
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G |
Il7r |
interleukin 7 receptor |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of IL7R mRNA |
CTD |
PMID:14699072 |
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NCBI chr 2:58,452,393...58,477,757
Ensembl chr 2:58,454,217...58,477,757
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G |
Ilrun |
inflammation and lipid regulator with UBA-like and NBR1-like domains |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of ILRUN mRNA |
CTD |
PMID:16514628 |
|
NCBI chr20:5,809,931...5,876,197
Ensembl chr20:5,809,936...5,876,012
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G |
Inhba |
inhibin subunit beta A |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of INHBA mRNA |
CTD |
PMID:19059307 |
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NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982
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G |
Inpp4b |
inositol polyphosphate-4-phosphatase type II B |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of INPP4B mRNA |
CTD |
PMID:14699072 |
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NCBI chr19:25,920,189...26,670,085
Ensembl chr19:25,925,358...26,280,634
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G |
Inpp5a |
inositol polyphosphate-5-phosphatase A |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of INPP5A mRNA |
CTD |
PMID:19059307 |
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NCBI chr 1:194,190,086...194,380,429
Ensembl chr 1:194,190,393...194,380,428
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G |
Ins1 |
insulin 1 |
multiple interactions |
ISO |
IWR-1 compound inhibits the reaction [Raloxifene Hydrochloride inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CTNNB1 protein]]; IWR-1 compound inhibits the reaction [Raloxifene Hydrochloride inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CEBPA protein]]; IWR-1 compound inhibits the reaction [Raloxifene Hydrochloride inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of PPARG protein]]; Raloxifene Hydrochloride affects the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of FABP4 protein]; Raloxifene Hydrochloride inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CTNNB1 protein]; Raloxifene Hydrochloride inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CEBPA protein]; Raloxifene Hydrochloride inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of PPARG protein] |
CTD |
PMID:31470850 |
|
NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
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G |
Insig1 |
insulin induced gene 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of INSIG1 mRNA |
CTD |
PMID:16497877 |
|
NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
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G |
Iqgap1 |
IQ motif containing GTPase activating protein 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of IQGAP1 mRNA |
CTD |
PMID:16514628 |
|
NCBI chr 1:134,679,581...134,769,776
Ensembl chr 1:134,679,586...134,769,755
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G |
Irf7 |
interferon regulatory factor 7 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of IRF7 mRNA |
CTD |
PMID:16079270 |
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NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832
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G |
Isg20 |
interferon stimulated exonuclease gene 20 |
multiple interactions affects expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of ISG20 mRNA Raloxifene Hydrochloride affects the expression of ISG20 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr 1:132,829,303...132,837,027
Ensembl chr 1:132,815,123...132,837,027
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G |
Itgb1 |
integrin subunit beta 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of ITGB1 mRNA |
CTD |
PMID:12154049 PMID:19429434 |
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NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
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G |
Itgb3 |
integrin subunit beta 3 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of ITGB3 mRNA |
CTD |
PMID:26603317 |
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NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
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G |
Itpr3 |
inositol 1,4,5-trisphosphate receptor, type 3 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ITPR3 mRNA |
CTD |
PMID:14699072 |
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NCBI chr20:5,136,968...5,202,339
Ensembl chr20:5,136,441...5,202,337
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G |
Ivl |
involucrin |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of IVL mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of IVL mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr 2:178,146,694...178,160,807
Ensembl chr 2:178,147,061...178,149,100
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G |
Jag1 |
jagged canonical Notch ligand 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of JAG1 mRNA |
CTD |
PMID:19059307 |
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NCBI chr 3:124,406,783...124,442,220
Ensembl chr 3:124,406,794...124,442,209
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G |
Jak2 |
Janus kinase 2 |
multiple interactions decreases expression |
ISO |
Raloxifene Hydrochloride promotes the reaction [GH1 protein results in increased phosphorylation of JAK2 protein] Raloxifene Hydrochloride results in decreased expression of JAK2 mRNA |
CTD |
PMID:17272397 PMID:26865669 |
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NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
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G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of JUN mRNA |
CTD |
PMID:12154049 |
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NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
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G |
Kazn |
kazrin, periplakin interacting protein |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of KAZN mRNA |
CTD |
PMID:19059307 |
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NCBI chr 5:154,392,793...155,381,567
Ensembl chr 5:154,392,793...154,779,074
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G |
Kcnd3 |
potassium voltage-gated channel subfamily D member 3 |
multiple interactions decreases activity decreases expression |
EXP ISO |
Raloxifene Hydrochloride promotes the reaction [Fulvestrant results in decreased activity of KCND3 protein] Raloxifene Hydrochloride results in decreased activity of KCND3 protein [KCNIP2 protein co-treated with Raloxifene Hydrochloride] results in decreased activity of KCND3 protein Raloxifene Hydrochloride results in decreased expression of KCND3 mRNA |
CTD |
PMID:25231973 |
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NCBI chr 2:192,937,950...193,155,345
Ensembl chr 2:192,937,950...193,155,345
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G |
Kcne1 |
potassium voltage-gated channel subfamily E regulatory subunit 1 |
increases expression |
EXP |
Raloxifene Hydrochloride results in increased expression of KCNE1 mRNA |
CTD |
PMID:15576828 |
|
NCBI chr11:31,580,951...31,594,116
Ensembl chr11:31,580,742...31,593,901
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G |
Kcnh5 |
potassium voltage-gated channel subfamily H member 5 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of KCNH5 mRNA |
CTD |
PMID:16079270 |
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NCBI chr 6:93,615,174...93,908,107
Ensembl chr 6:93,624,529...93,908,107
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G |
Kcnip2 |
potassium voltage-gated channel interacting protein 2 |
multiple interactions |
ISO |
[KCNIP2 protein co-treated with Raloxifene Hydrochloride] results in decreased activity of KCND3 protein |
CTD |
PMID:25231973 |
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NCBI chr 1:244,641,147...244,664,939
Ensembl chr 1:244,641,150...244,664,874
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G |
Kcnn4 |
potassium calcium-activated channel subfamily N member 4 |
multiple interactions affects expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of KCNN4 mRNA Raloxifene Hydrochloride affects the expression of KCNN4 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr 1:79,956,380...79,974,354
Ensembl chr 1:79,959,322...79,974,340
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G |
Kctd12 |
potassium channel tetramerization domain containing 12 |
multiple interactions affects expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of KCTD12 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of KCTD12 mRNA Raloxifene Hydrochloride affects the expression of KCTD12 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr15:79,800,078...79,806,017
Ensembl chr15:79,801,191...79,806,282
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G |
Kif20a |
kinesin family member 20A |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of KIF20A mRNA |
CTD |
PMID:16514628 |
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NCBI chr18:26,230,294...26,238,780
Ensembl chr18:26,230,230...26,238,780
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G |
Kif3c |
kinesin family member 3C |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of KIF3C mRNA |
CTD |
PMID:19059307 |
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NCBI chr 6:26,367,092...26,406,033
Ensembl chr 6:26,366,531...26,406,130
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G |
Kiss1 |
KiSS-1 metastasis-suppressor |
decreases expression |
EXP |
Raloxifene Hydrochloride results in decreased expression of KISS1 mRNA |
CTD |
PMID:27395752 |
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NCBI chr13:44,775,106...44,780,707
Ensembl chr13:44,774,823...44,780,612
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G |
Klf10 |
KLF transcription factor 10 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of KLF10 mRNA |
CTD |
PMID:14699072 |
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NCBI chr 7:69,467,658...69,473,726
Ensembl chr 7:69,465,619...69,473,994
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G |
Klf6 |
KLF transcription factor 6 |
decreases expression |
EXP |
Raloxifene Hydrochloride results in decreased expression of KLF6 mRNA |
CTD |
PMID:15576828 |
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NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570
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G |
Klhl24 |
kelch-like family member 24 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of KLHL24 mRNA |
CTD |
PMID:19429434 |
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NCBI chr11:80,843,621...80,877,649
Ensembl chr11:80,846,755...80,877,636
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G |
Klrc1 |
killer cell lectin like receptor C1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of KLRC1 mRNA |
CTD |
PMID:17962382 |
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NCBI chr 4:163,142,142...163,152,425
Ensembl chr 4:163,147,189...163,152,425
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G |
Klrc2 |
killer cell lectin like receptor C2 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of KLRC2 mRNA [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of KLRC2 mRNA; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of KLRC2 mRNA]; ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of KLRC2 mRNA] |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr 4:163,122,700...163,133,843
Ensembl chr 4:163,122,704...163,133,843
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G |
Klrc3 |
killer cell lectin like receptor C3 |
multiple interactions increases expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of KLRC3 mRNA; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of KLRC3 mRNA]; Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of KLRC3 mRNA]; Raloxifene Hydrochloride promotes the reaction [ESR1 protein binds to KLRC3 gene]; Raloxifene Hydrochloride promotes the reaction [NCOA3 protein binds to KLRC3 gene] |
CTD |
PMID:17395694 PMID:19059307 |
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NCBI chr 4:163,105,081...163,112,737
Ensembl chr 4:163,106,024...163,112,336
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G |
Klrk1 |
killer cell lectin like receptor K1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of KLRK1 mRNA |
CTD |
PMID:19059307 |
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NCBI chr 4:163,079,887...163,092,434
Ensembl chr 4:163,081,927...163,092,459
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G |
Kpna2 |
karyopherin subunit alpha 2 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of KPNA2 mRNA |
CTD |
PMID:16514628 |
|
NCBI chr10:91,933,951...91,946,115
Ensembl chr10:91,933,951...91,946,150
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G |
Kpnb1 |
karyopherin subunit beta 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of KPNB1 mRNA |
CTD |
PMID:16514628 |
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NCBI chr10:82,145,662...82,174,437
Ensembl chr10:82,145,420...82,174,605
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G |
Krt17 |
keratin 17 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of KRT17 mRNA |
CTD |
PMID:19059307 |
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NCBI chr10:85,178,673...85,183,392
Ensembl chr10:85,178,675...85,183,392
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G |
Krt34 |
keratin 34 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of KRT34 mRNA |
CTD |
PMID:19059307 |
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NCBI chr10:84,969,988...84,974,098
Ensembl chr10:84,970,017...84,974,040
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G |
L3mbtl1 |
L3MBTL histone methyl-lysine binding protein 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of L3MBTL1 mRNA |
CTD |
PMID:19429434 |
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NCBI chr 3:151,597,903...151,633,657
Ensembl chr 3:151,602,980...151,631,233
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G |
Lamb1 |
laminin subunit beta 1 |
multiple interactions |
ISO |
[APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of LAMB1 mRNA |
CTD |
PMID:24431404 |
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NCBI chr 6:47,835,492...47,902,585
Ensembl chr 6:47,835,525...47,902,585
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G |
Lamc1 |
laminin subunit gamma 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of LAMC1 mRNA |
CTD |
PMID:14699072 |
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NCBI chr13:65,374,372...65,501,492
Ensembl chr13:65,374,372...65,501,492
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G |
Lbh |
LBH regulator of WNT signaling pathway |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of LBH mRNA |
CTD |
PMID:19059307 |
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NCBI chr 6:22,569,238...22,593,056
Ensembl chr 6:22,568,834...22,593,079
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G |
Lcn2 |
lipocalin 2 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of LCN2 mRNA |
CTD |
PMID:14699072 |
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NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
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G |
Ldlr |
low density lipoprotein receptor |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of LDLR mRNA |
CTD |
PMID:16497877 |
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NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
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G |
Ldlrad4 |
low density lipoprotein receptor class A domain containing 4 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of LDLRAD4 mRNA |
CTD |
PMID:19059307 |
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NCBI chr18:61,519,253...61,848,403
Ensembl chr18:61,521,428...61,843,238
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G |
Lepr |
leptin receptor |
affects expression |
EXP |
Raloxifene decreases Lepr protein expression in adipose tissue at 7 weeks and increases it at 22 weeks |
RGD |
PMID:15059958 |
RGD:1581837 |
NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
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G |
Lgr5 |
leucine rich repeat containing G protein coupled receptor 5 |
multiple interactions |
ISO |
[APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of LGR5 mRNA; [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of LGR5 protein |
CTD |
PMID:24431404 |
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NCBI chr 7:51,087,059...51,221,882
Ensembl chr 7:51,088,239...51,222,446
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G |
Lhb |
luteinizing hormone subunit beta |
multiple interactions decreases secretion |
EXP |
Raloxifene Hydrochloride inhibits the reaction [estradiol 3-benzoate results in increased secretion of LHB protein] Raloxifene Hydrochloride results in decreased secretion of LHB protein |
CTD |
PMID:17398000 PMID:27395752 |
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NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972 Ensembl chr 1:95,900,984...95,901,972
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G |
Lif |
LIF, interleukin 6 family cytokine |
multiple interactions decreases expression |
ISO |
[Raloxifene Hydrochloride co-treated with PX-866] results in decreased expression of LIF mRNA Raloxifene Hydrochloride results in decreased expression of LIF mRNA |
CTD |
PMID:26603317 PMID:27017931 |
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NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482
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G |
Limch1 |
LIM and calponin homology domains 1 |
multiple interactions |
ISO |
Raloxifene Hydrochloride promotes the reaction [Estradiol results in increased expression of LIMCH1 mRNA] |
CTD |
PMID:21185374 |
|
NCBI chr14:41,112,579...41,425,001
Ensembl chr14:41,114,803...41,425,191
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G |
Liph |
lipase H |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with Estradiol] results in increased expression of LIPH mRNA |
CTD |
PMID:21185374 |
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NCBI chr11:79,032,229...79,081,625
Ensembl chr11:79,033,312...79,081,625
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G |
Lmcd1 |
LIM and cysteine-rich domains 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of LMCD1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of LMCD1 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 4:145,393,153...145,452,049
Ensembl chr 4:145,393,145...145,452,046
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G |
Lmnb2 |
lamin B2 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of LMNB2 mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of LMNB2 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr 7:8,792,628...8,808,665
Ensembl chr 7:8,789,314...8,808,665
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G |
Lox |
lysyl oxidase |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of LOX mRNA |
CTD |
PMID:16079270 |
|
NCBI chr18:45,964,544...45,977,431
Ensembl chr18:45,967,343...46,041,477
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G |
Lpl |
lipoprotein lipase |
multiple interactions increases expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of LPL mRNA Raloxifene Hydrochloride results in increased expression of LPL mRNA |
CTD |
PMID:16643890 PMID:19059307 |
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NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
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G |
Lrig1 |
leucine-rich repeats and immunoglobulin-like domains 1 |
multiple interactions affects expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of LRIG1 mRNA Raloxifene Hydrochloride affects the expression of LRIG1 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr 4:127,130,899...127,230,956
Ensembl chr 4:127,130,898...127,231,513
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G |
Lrrc20 |
leucine rich repeat containing 20 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of LRRC20 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr20:29,422,858...29,528,372
Ensembl chr20:29,422,925...29,528,369
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G |
Ltb |
lymphotoxin beta |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of LTB mRNA |
CTD |
PMID:19429434 |
|
NCBI chr20:3,627,536...3,629,381
Ensembl chr20:3,627,537...3,629,381
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G |
Ltbp1 |
latent transforming growth factor beta binding protein 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of LTBP1 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 6:20,029,629...20,425,339
Ensembl chr 6:20,029,629...20,425,349
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G |
Lum |
lumican |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of LUM mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 7:32,358,990...32,365,794
Ensembl chr 7:32,358,614...32,365,793
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G |
Ly6i |
lymphocyte antigen 6 complex, locus I |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of LY6B mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 7:107,062,320...107,067,743
Ensembl chr 7:107,062,325...107,067,310
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G |
Lyn |
LYN proto-oncogene, Src family tyrosine kinase |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with Estradiol] results in increased expression of LYN mRNA |
CTD |
PMID:21185374 |
|
NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868
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G |
Lysmd4 |
LysM domain containing 4 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of LYSMD4 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 1:120,839,180...120,845,148
Ensembl chr 1:120,839,282...120,845,135
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G |
Macroh2a1 |
macroH2A.1 histone |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of MACROH2A1 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr17:8,479,331...8,542,071
Ensembl chr17:8,479,372...8,542,072
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G |
Maf |
MAF bZIP transcription factor |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of MAF mRNA |
CTD |
PMID:19429434 |
|
NCBI chr19:43,353,867...43,713,162
Ensembl chr19:43,360,342...43,712,365
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G |
Maff |
MAF bZIP transcription factor F |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MAFF mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851
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G |
Man2a2 |
mannosidase, alpha, class 2A, member 2 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of MAN2A2 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 1:134,304,714...134,327,611
Ensembl chr 1:134,306,236...134,327,315
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G |
Map1lc3b |
microtubule-associated protein 1 light chain 3 beta |
multiple interactions increases lipidation |
ISO |
[Raloxifene Hydrochloride co-treated with Oxygen deficiency] results in increased lipidation of MAP1LC3B protein Raloxifene Hydrochloride results in increased lipidation of MAP1LC3B protein |
CTD |
PMID:33203845 |
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NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690 Ensembl chr16:49,665,791...49,677,690
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G |
Map2k3 |
mitogen activated protein kinase kinase 3 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of MAP2K3 mRNA |
CTD |
PMID:19059307 |
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NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492
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G |
Map2k6 |
mitogen-activated protein kinase kinase 6 |
multiple interactions |
ISO |
MAP2K6 protein promotes the reaction [Raloxifene Hydrochloride results in increased expression of HMOX1 protein] |
CTD |
PMID:20888885 |
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NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293
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Map3k11 |
mitogen-activated protein kinase kinase kinase 11 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of MAP3K11 mRNA |
CTD |
PMID:12154049 |
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NCBI chr 1:202,975,353...202,988,655
Ensembl chr 1:202,975,353...202,988,652
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Map3k20 |
mitogen-activated protein kinase kinase kinase 20 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of MAP3K20 mRNA |
CTD |
PMID:19429434 |
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NCBI chr 3:57,130,539...57,289,943
Ensembl chr 3:57,130,551...57,289,626
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G |
Map3k5 |
mitogen-activated protein kinase kinase kinase 5 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MAP3K5 mRNA |
CTD |
PMID:19059307 |
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NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800
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Map3k8 |
mitogen-activated protein kinase kinase kinase 8 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MAP3K8 mRNA |
CTD |
PMID:19059307 |
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NCBI chr17:53,382,908...53,403,216
Ensembl chr17:53,383,131...53,403,216
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions increases phosphorylation |
ISO EXP |
U 0126 inhibits the reaction [Raloxifene Hydrochloride results in increased phosphorylation of MAPK1 protein] 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [Raloxifene Hydrochloride results in increased phosphorylation of MAPK1 protein]; Raloxifene Hydrochloride inhibits the reaction [Methylmercury Compounds results in increased activity of MAPK1 protein]; sotrastaurin inhibits the reaction [Raloxifene Hydrochloride results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [Raloxifene Hydrochloride results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:15712295 PMID:16798746 PMID:17174166 PMID:20945400 PMID:24782323 PMID:26200092 More...
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NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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Mapk14 |
mitogen activated protein kinase 14 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of MAPK14 mRNA |
CTD |
PMID:16079270 |
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NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions increases phosphorylation |
ISO EXP |
4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [Raloxifene Hydrochloride results in increased phosphorylation of MAPK3 protein]; Raloxifene Hydrochloride inhibits the reaction [Methylmercury Compounds results in increased activity of MAPK3 protein]; sotrastaurin inhibits the reaction [Raloxifene Hydrochloride results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [Raloxifene Hydrochloride results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:15712295 PMID:16798746 PMID:17174166 PMID:20945400 PMID:24782323 PMID:26200092 More...
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NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Mapkapk2 |
MAPK activated protein kinase 2 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MAPKAPK2 mRNA |
CTD |
PMID:19059307 |
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NCBI chr13:42,513,762...42,560,061
Ensembl chr13:42,513,762...42,560,457
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G |
Marcksl1 |
MARCKS-like 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of MARCKSL1 mRNA |
CTD |
PMID:14699072 |
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NCBI chr 5:141,851,491...141,853,814
Ensembl chr 5:141,850,110...141,853,817
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Matr3 |
matrin 3 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of MATR3 mRNA |
CTD |
PMID:16514628 |
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NCBI chr18:27,154,098...27,193,212
Ensembl chr18:27,163,714...27,193,166
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G |
Mbnl2 |
muscleblind-like splicing regulator 2 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MBNL2 mRNA |
CTD |
PMID:19059307 |
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NCBI chr15:97,385,278...97,542,924
Ensembl chr15:97,385,244...97,542,937
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Mctp1 |
multiple C2 and transmembrane domain containing 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of MCTP1 mRNA |
CTD |
PMID:19429434 |
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NCBI chr 2:6,071,408...6,761,833
Ensembl chr 2:6,065,808...6,761,833
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G |
Mdfic |
MyoD family inhibitor domain containing |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of MDFIC mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MDFIC mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr 4:43,972,310...44,052,162
Ensembl chr 4:43,972,507...44,052,161
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G |
Mdm2 |
MDM2 proto-oncogene |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with PX-866] results in decreased phosphorylation of MDM2 protein |
CTD |
PMID:27017931 |
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NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
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G |
Mef2a |
myocyte enhancer factor 2a |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MEF2A mRNA |
CTD |
PMID:19059307 |
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NCBI chr 1:120,847,874...120,982,488
Ensembl chr 1:120,850,080...120,981,948
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Mfap5 |
microfibril associated protein 5 |
multiple interactions affects expression |
ISO |
ESR1 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of MFAP5 mRNA] Raloxifene Hydrochloride affects the expression of MFAP5 mRNA |
CTD |
PMID:14699072 |
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NCBI chr 4:155,727,925...155,750,458
Ensembl chr 4:155,727,925...155,750,458
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G |
Mgp |
matrix Gla protein |
multiple interactions decreases expression |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of MGP mRNA] Raloxifene Hydrochloride results in decreased expression of MGP mRNA |
CTD |
PMID:16514628 PMID:21185374 |
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NCBI chr 4:169,766,290...169,769,612
Ensembl chr 4:169,766,279...169,769,667
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Mical2 |
microtubule associated monooxygenase, calponin and LIM domain containing 2 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of MICAL2 mRNA |
CTD |
PMID:26865669 |
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NCBI chr 1:166,345,853...166,530,575
Ensembl chr 1:166,345,859...166,471,719 Ensembl chr 1:166,345,859...166,471,719
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Mid1 |
midline 1 |
multiple interactions |
ISO |
Raloxifene Hydrochloride promotes the reaction [Estradiol results in increased expression of MID1 mRNA] |
CTD |
PMID:21185374 |
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NCBI chr X:24,116,674...24,491,205
Ensembl chr X:24,120,293...24,248,353
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Mki67 |
marker of proliferation Ki-67 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of MKI67 protein |
CTD |
PMID:11535548 |
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NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
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G |
Mmd2 |
monocyte to macrophage differentiation-associated 2 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of MMD2 mRNA |
CTD |
PMID:22841776 |
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NCBI chr12:11,962,733...12,009,776
Ensembl chr12:11,962,757...12,009,773
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Mmp12 |
matrix metallopeptidase 12 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of MMP12 mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MMP12 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611
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G |
Mmp13 |
matrix metallopeptidase 13 |
multiple interactions |
EXP |
Raloxifene Hydrochloride inhibits the reaction [Decitabine results in increased expression of MMP13 mRNA] |
CTD |
PMID:23385821 |
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NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239
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G |
Mmp2 |
matrix metallopeptidase 2 |
affects expression multiple interactions |
EXP ISO |
Raloxifene Hydrochloride affects the expression of MMP2 mRNA 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Raloxifene Hydrochloride inhibits the reaction [Streptozocin results in decreased secretion of MMP2 protein]]; ESR2 protein affects the reaction [Raloxifene Hydrochloride inhibits the reaction [Streptozocin results in decreased secretion of MMP2 protein]]; Raloxifene Hydrochloride inhibits the reaction [Streptozocin results in decreased expression of MMP2 mRNA]; Raloxifene Hydrochloride inhibits the reaction [Streptozocin results in decreased secretion of MMP2 protein] |
CTD |
PMID:16079270 PMID:23471663 |
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NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
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G |
Mmp3 |
matrix metallopeptidase 3 |
multiple interactions |
EXP |
Raloxifene Hydrochloride inhibits the reaction [Decitabine results in increased expression of MMP3 mRNA] |
CTD |
PMID:23385821 |
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NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
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Mmp9 |
matrix metallopeptidase 9 |
decreases activity decreases expression increases expression multiple interactions |
ISO EXP |
Raloxifene Hydrochloride results in decreased activity of MMP9 protein Raloxifene Hydrochloride results in decreased expression of MMP9 mRNA Raloxifene Hydrochloride results in increased expression of MMP9 mRNA [9,10-Dimethyl-1,2-benzanthracene co-treated with Raloxifene Hydrochloride co-treated with Fluoxetine] affects the expression of MMP9 protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with Raloxifene Hydrochloride] affects the expression of MMP9 protein |
CTD |
PMID:17582780 PMID:22841776 PMID:31332895 |
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NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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G |
Mn1 |
MN1 proto-oncogene, transcriptional regulator |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MN1 mRNA |
CTD |
PMID:19059307 |
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NCBI chr12:45,181,794...45,220,959
Ensembl chr12:45,183,085...45,221,651
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G |
Mpo |
myeloperoxidase |
multiple interactions |
EXP |
Carrageenan inhibits the reaction [Raloxifene Hydrochloride results in increased activity of MPO protein] |
CTD |
PMID:15860553 |
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NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
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G |
Mpped2 |
metallophosphoesterase domain containing 2 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MPPED2 mRNA |
CTD |
PMID:19059307 |
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NCBI chr 3:93,180,895...93,355,605
Ensembl chr 3:93,181,167...93,355,618
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G |
Mr1 |
major histocompatibility complex, class I-related |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of MR1 mRNA |
CTD |
PMID:19429434 |
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NCBI chr13:67,298,362...67,317,985
Ensembl chr13:67,299,585...67,317,970
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G |
Mrpl33 |
mitochondrial ribosomal protein L33 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of MRPL33 mRNA |
CTD |
PMID:14699072 |
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NCBI chr 6:24,825,800...24,833,994
Ensembl chr 6:24,825,827...24,833,834
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G |
Msmb |
microseminoprotein, beta |
multiple interactions affects expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of MSMB mRNA; ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of MSMB mRNA] Raloxifene Hydrochloride affects the expression of MSMB mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr16:7,366,536...7,387,124
Ensembl chr16:7,366,536...7,387,123
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G |
Mst1 |
macrophage stimulating 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of MST1 mRNA |
CTD |
PMID:19429434 |
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NCBI chr 8:108,767,886...108,773,425
Ensembl chr 8:108,768,839...108,773,416
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G |
Mt2A |
metallothionein 2A |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of MT2A mRNA |
CTD |
PMID:20945400 |
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NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
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G |
Mthfr |
methylenetetrahydrofolate reductase |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of MTHFR mRNA |
CTD |
PMID:15849065 |
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NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797
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G |
Mtor |
mechanistic target of rapamycin kinase |
increases phosphorylation |
ISO |
Raloxifene Hydrochloride results in increased phosphorylation of MTOR protein |
CTD |
PMID:25537862 |
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NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
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G |
Muc1 |
mucin 1, cell surface associated |
increases expression affects expression |
ISO EXP |
Raloxifene Hydrochloride results in increased expression of MUC1 protein Raloxifene Hydrochloride affects the expression of MUC1 mRNA |
CTD |
PMID:16012748 PMID:16079270 |
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NCBI chr 2:174,635,989...174,640,738
Ensembl chr 2:174,635,995...174,640,733
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G |
Myb |
MYB proto-oncogene, transcription factor |
multiple interactions decreases expression |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of MYB mRNA] Raloxifene Hydrochloride results in decreased expression of MYB mRNA |
CTD |
PMID:21185374 PMID:26865669 |
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NCBI chr 1:15,939,771...15,973,367
Ensembl chr 1:15,939,761...15,973,057
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G |
Mybl1 |
MYB proto-oncogene like 1 |
multiple interactions decreases expression |
ISO |
[Raloxifene Hydrochloride co-treated with Estradiol] results in decreased expression of MYBL1 mRNA Raloxifene Hydrochloride results in decreased expression of MYBL1 mRNA |
CTD |
PMID:21185374 PMID:26865669 |
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NCBI chr 5:9,582,905...9,618,179
Ensembl chr 5:9,582,934...9,618,183
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Myc |
MYC proto-oncogene, bHLH transcription factor |
multiple interactions decreases expression increases expression |
ISO |
GPER1 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of MYC mRNA]; Raloxifene Hydrochloride inhibits the reaction [[NRG1 protein co-treated with Estradiol] results in increased expression of MYC protein] Raloxifene Hydrochloride results in decreased expression of MYC mRNA; Raloxifene Hydrochloride results in decreased expression of MYC protein |
CTD |
PMID:16497877 PMID:20945400 PMID:22453024 PMID:26502914 |
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NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
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Myl9 |
myosin light chain 9 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of MYL9 mRNA |
CTD |
PMID:16079270 |
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NCBI chr 3:145,281,943...145,288,333
Ensembl chr 3:145,281,937...145,288,333
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Myo10 |
myosin X |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of MYO10 mRNA |
CTD |
PMID:14699072 |
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NCBI chr 2:76,100,989...76,305,619
Ensembl chr 2:76,100,987...76,303,030
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Myod1 |
myogenic differentiation 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of MYOD1 mRNA |
CTD |
PMID:19432593 |
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NCBI chr 1:96,884,864...96,887,574
Ensembl chr 1:96,884,948...96,887,554
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G |
Myt1l |
myelin transcription factor 1-like |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MYT1L mRNA |
CTD |
PMID:19059307 |
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NCBI chr 6:46,164,742...46,564,234
Ensembl chr 6:46,428,150...46,561,671
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G |
Nab1 |
Ngfi-A binding protein 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of NAB1 mRNA |
CTD |
PMID:19059307 |
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NCBI chr 9:49,053,579...49,093,078
Ensembl chr 9:49,053,758...49,092,098
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G |
Nars1 |
asparaginyl-tRNA synthetase 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of NARS1 mRNA |
CTD |
PMID:16514628 |
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NCBI chr18:57,989,308...58,005,584
Ensembl chr18:57,989,308...58,005,622
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G |
Nav2 |
neuron navigator 2 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NAV2 mRNA |
CTD |
PMID:19059307 |
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NCBI chr 1:98,957,629...99,322,339
Ensembl chr 1:98,663,759...99,322,337
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G |
Nbl1 |
NBL1, DAN family BMP antagonist |
increases expression |
EXP |
Raloxifene Hydrochloride results in increased expression of NBL1 mRNA |
CTD |
PMID:15576828 |
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NCBI chr 5:151,318,752...151,329,948
Ensembl chr 5:151,318,754...151,338,719
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G |
Ncaph |
non-SMC condensin I complex, subunit H |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of NCAPH mRNA |
CTD |
PMID:16514628 |
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NCBI chr 3:114,371,937...114,399,178
Ensembl chr 3:114,371,941...114,399,180
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G |
Ncf2 |
neutrophil cytosolic factor 2 |
multiple interactions affects expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NCF2 mRNA; ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of NCF2 mRNA] Raloxifene Hydrochloride affects the expression of NCF2 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr13:64,955,622...64,986,144
Ensembl chr13:64,955,503...64,986,277
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Ncl |
nucleolin |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of NCL mRNA |
CTD |
PMID:16514628 |
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NCBI chr 9:86,999,588...87,008,112
Ensembl chr 9:86,998,019...87,008,136
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G |
Ncoa1 |
nuclear receptor coactivator 1 |
multiple interactions increases expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NCOA1 mRNA; Raloxifene Hydrochloride promotes the reaction [NCOA1 protein binds to IGF1 promoter] Raloxifene Hydrochloride results in increased expression of NCOA1 mRNA |
CTD |
PMID:17872375 PMID:19059307 PMID:19432593 |
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NCBI chr 6:27,232,609...27,507,992
Ensembl chr 6:27,232,611...27,475,664
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G |
Ncoa2 |
nuclear receptor coactivator 2 |
multiple interactions increases expression |
ISO |
Raloxifene Hydrochloride promotes the reaction [NCOA2 protein binds to IGF1 promoter]; Raloxifene Hydrochloride promotes the reaction [NCOA2 protein binds to PTGS2 promoter] Raloxifene Hydrochloride results in increased expression of NCOA2 protein |
CTD |
PMID:16739346 PMID:17872375 |
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NCBI chr 5:5,835,642...6,069,693
Ensembl chr 5:5,835,706...6,067,451
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G |
Ncoa3 |
nuclear receptor coactivator 3 |
multiple interactions |
ISO |
Raloxifene Hydrochloride promotes the reaction [NCOA3 protein binds to IGF1 promoter]; Raloxifene Hydrochloride promotes the reaction [NCOA3 protein binds to KLRC3 gene]; Raloxifene Hydrochloride promotes the reaction [NCOA3 protein binds to PTGS2 promoter] |
CTD |
PMID:17395694 PMID:17872375 |
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NCBI chr 3:154,738,566...154,821,395
Ensembl chr 3:154,738,581...154,818,594
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G |
Ncoa4 |
nuclear receptor coactivator 4 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of NCOA4 mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NCOA4 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr16:7,389,222...7,409,564
Ensembl chr16:7,366,542...7,409,641 Ensembl chr16:7,366,542...7,409,641
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G |
Ncor2 |
nuclear receptor co-repressor 2 |
multiple interactions decreases expression |
ISO |
Raloxifene Hydrochloride inhibits the reaction [NCOR2 protein binds to IGF1 promoter]; Raloxifene Hydrochloride inhibits the reaction [NCOR2 protein binds to PTGS2 promoter] Raloxifene Hydrochloride results in decreased expression of NCOR2 mRNA |
CTD |
PMID:17872375 PMID:19432593 |
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NCBI chr12:31,466,418...31,628,319
Ensembl chr12:31,466,412...31,628,319
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G |
Ndrg4 |
NDRG family member 4 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NDRG4 mRNA |
CTD |
PMID:19059307 |
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NCBI chr19:9,351,408...9,387,398
Ensembl chr19:9,351,404...9,386,914
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G |
Ndufa2 |
NADH:ubiquinone oxidoreductase subunit A2 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of NDUFA2 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr18:28,355,774...28,357,863
Ensembl chr18:28,355,774...28,358,076
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G |
Nectin1 |
nectin cell adhesion molecule 1 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of NECTIN1 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 8:44,101,776...44,164,863
Ensembl chr 8:44,101,776...44,189,787
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G |
Nefl |
neurofilament light chain |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of NEFL mRNA |
CTD |
PMID:14699072 |
|
NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793
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G |
Nek7 |
NIMA-related kinase 7 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of NEK7 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr13:50,022,212...50,149,374
Ensembl chr13:50,022,218...50,149,296
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G |
Nf1 |
neurofibromin 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of NF1 mRNA |
CTD |
PMID:19429434 |
|
NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658
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G |
Nfatc1 |
nuclear factor of activated T-cells 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NFATC1 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr18:74,046,422...74,156,041
Ensembl chr18:74,046,904...74,156,028
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G |
Nfe2l1 |
NFE2 like bZIP transcription factor 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of NFE2L1 mRNA |
CTD |
PMID:16497877 |
|
NCBI chr10:81,796,055...81,812,926
Ensembl chr10:81,800,366...81,832,318
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G |
Nfil3 |
nuclear factor, interleukin 3 regulated |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of NFIL3 mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NFIL3 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
|
NCBI chr17:12,280,499...12,295,728
Ensembl chr17:12,280,484...12,295,858
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G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
multiple interactions |
EXP |
Raloxifene Hydrochloride promotes the reaction [NFKB1 protein binds to SLC1A2 promoter] |
CTD |
PMID:24782323 |
|
NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
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G |
Nfkbia |
NFKB inhibitor alpha |
multiple interactions decreases expression affects expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NFKBIA mRNA Raloxifene Hydrochloride results in decreased expression of NFKBIA mRNA Raloxifene Hydrochloride affects the expression of NFKBIA mRNA Raloxifene Hydrochloride inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]; SFRP5 protein affects the reaction [Raloxifene Hydrochloride inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]] |
CTD |
PMID:14699072 PMID:16298037 PMID:19059307 PMID:31470850 |
|
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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G |
Nfkbie |
NFKB inhibitor epsilon |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of NFKBIE mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 9:15,443,600...15,450,437
Ensembl chr 9:15,436,941...15,450,437
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G |
Nherf1 |
NHERF family PDZ scaffold protein 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of NHERF1 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr10:100,403,189...100,420,290
Ensembl chr10:100,403,069...100,420,598
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G |
Ninj1 |
ninjurin 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NINJ1 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr17:15,452,804...15,461,684
Ensembl chr17:15,452,813...15,461,704
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G |
Nlrp3 |
NLR family, pyrin domain containing 3 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of NLRP3 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
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G |
Nme6 |
NME/NM23 nucleoside diphosphate kinase 6 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of NME6 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 8:109,832,085...109,839,301
Ensembl chr 8:109,832,589...109,839,301
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G |
Nmrk1 |
nicotinamide riboside kinase 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of NMRK1 mRNA |
CTD |
PMID:26865669 |
|
NCBI chr 1:216,049,350...216,076,792
Ensembl chr 1:216,049,437...216,076,791
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G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions decreases expression |
ISO EXP |
[Raloxifene Hydrochloride co-treated with 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid] results in increased expression of NOS2 protein; [Raloxifene Hydrochloride results in decreased expression of NOS2 protein] which results in decreased chemical synthesis of Nitric Oxide; Cycloheximide inhibits the reaction [[Raloxifene Hydrochloride co-treated with 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid] results in increased expression of NOS2 protein]; Dactinomycin inhibits the reaction [[Raloxifene Hydrochloride co-treated with 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid] results in increased expression of NOS2 protein]; Fulvestrant inhibits the reaction [[Raloxifene Hydrochloride co-treated with 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid] results in increased expression of NOS2 protein]; HMOX1 protein promotes the reaction [[Raloxifene Hydrochloride results in decreased expression of NOS2 protein] which results in decreased chemical synthesis of Nitric Oxide]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Raloxifene Hydrochloride co-treated with 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid] results in increased expression of NOS2 protein]; XDH protein promotes the reaction [[Raloxifene Hydrochloride results in decreased expression of NOS2 protein] which results in decreased chemical synthesis of Nitric Oxide] Carrageenan inhibits the reaction [Raloxifene Hydrochloride results in increased expression of NOS2 protein] |
CTD |
PMID:15860553 PMID:20888885 PMID:28138957 |
|
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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G |
Nos3 |
nitric oxide synthase 3 |
increases expression |
EXP |
Raloxifene Hydrochloride results in increased expression of NOS3 mRNA |
CTD |
PMID:11779577 |
|
NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
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G |
Notch3 |
notch receptor 3 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of NOTCH3 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 7:11,132,984...11,184,025
Ensembl chr 7:11,133,706...11,184,025
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G |
Npm1 |
nucleophosmin 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of NPM1 mRNA |
CTD |
PMID:16514628 |
|
NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645 Ensembl chr X:17,739,941...17,751,645
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G |
Npr2 |
natriuretic peptide receptor 2 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of NPR2 mRNA [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of NPR2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NPR2 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
|
NCBI chr 5:57,883,171...57,901,590
Ensembl chr 5:57,883,171...57,901,580
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G |
Npy1r |
neuropeptide Y receptor Y1 |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of NPY1R mRNA] |
CTD |
PMID:21185374 |
|
NCBI chr16:23,037,788...23,047,330
Ensembl chr16:23,037,789...23,046,759
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G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
increases expression multiple interactions |
ISO |
Raloxifene Hydrochloride results in increased expression of NQO1 protein ARNT protein affects the reaction [Raloxifene Hydrochloride results in increased expression of NQO1 protein] |
CTD |
PMID:24481452 |
|
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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G |
Nr1d1 |
nuclear receptor subfamily 1, group D, member 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NR1D1 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705
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G |
Nr2f6 |
nuclear receptor subfamily 2, group F, member 6 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of NR2F6 mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NR2F6 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
|
NCBI chr16:18,046,012...18,053,914
Ensembl chr16:18,046,013...18,053,459
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G |
Nr3c1 |
nuclear receptor subfamily 3, group C, member 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of NR3C1 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
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G |
Nr4a1 |
nuclear receptor subfamily 4, group A, member 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of NR4A1 mRNA |
CTD |
PMID:16514628 |
|
NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
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G |
Nr4a3 |
nuclear receptor subfamily 4, group A, member 3 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of NR4A3 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733
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G |
Nrep |
neuronal regeneration related protein |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of NREP mRNA |
CTD |
PMID:14699072 |
|
NCBI chr18:25,017,069...25,046,593
Ensembl chr18:25,017,083...25,046,591
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G |
Nrf1 |
nuclear respiratory factor 1 |
multiple interactions increases expression |
ISO |
fulvestrant inhibits the reaction [Raloxifene Hydrochloride results in increased expression of NRF1 mRNA]; Vehicle Emissions inhibits the reaction [Raloxifene Hydrochloride results in increased expression of NRF1 mRNA] |
CTD |
PMID:22105178 |
|
NCBI chr 4:58,664,932...58,772,328
Ensembl chr 4:58,664,957...58,825,328
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G |
Nrg1 |
neuregulin 1 |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [[NRG1 protein co-treated with Estradiol] results in increased expression of MYC protein] |
CTD |
PMID:26502914 |
|
NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884
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G |
Nrg2 |
neuregulin 2 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of NRG2 mRNA |
CTD |
PMID:15849065 |
|
NCBI chr18:27,616,542...27,798,505
Ensembl chr18:27,619,661...27,798,505
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G |
Nuak1 |
NUAK family kinase 1 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of NUAK1 mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NUAK1 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
|
NCBI chr 7:19,330,034...19,401,918
Ensembl chr 7:19,329,933...19,401,913
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G |
Nup160 |
nucleoporin 160 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of NUP160 mRNA |
CTD |
PMID:16497877 |
|
NCBI chr 3:76,665,786...76,729,296
Ensembl chr 3:76,665,786...76,724,565
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G |
Nus1 |
NUS1 dehydrodolichyl diphosphate synthase subunit |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of NUS1 mRNA |
CTD |
PMID:16514628 |
|
NCBI chr20:31,811,817...31,838,562
Ensembl chr20:31,811,817...31,838,561
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G |
Nxf1 |
nuclear RNA export factor 1 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of NXF1 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 1:205,655,442...205,668,637
Ensembl chr 1:205,655,375...205,668,636
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G |
Ocln |
occludin |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of OCLN mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150
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G |
Olfm1 |
olfactomedin 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of OLFM1 mRNA |
CTD |
PMID:26865669 |
|
NCBI chr 3:11,520,522...11,558,240
Ensembl chr 3:11,520,729...11,558,239
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G |
Olfml2a |
olfactomedin-like 2A |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of OLFML2A mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 3:22,688,590...22,717,917
Ensembl chr 3:22,688,598...22,717,909
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G |
Or10al6 |
olfactory receptor family 10 subfamily AL member 6 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of OR10AL6 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr20:738,257...739,607
Ensembl chr20:734,965...811,125
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G |
Or1f45 |
olfactory receptor family 1 subfamily F member 45 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of OR1F45 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr10:11,992,870...11,993,811
Ensembl chr10:11,992,870...11,993,811 Ensembl chr10:11,992,870...11,993,811
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G |
Osbpl3 |
oxysterol binding protein-like 3 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of OSBPL3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of OSBPL3 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 4:79,346,583...79,523,523
Ensembl chr 4:79,350,349...79,523,393
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G |
Osbpl7 |
oxysterol binding protein-like 7 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of OSBPL7 mRNA |
CTD |
PMID:19429434 |
|
NCBI chr10:82,035,995...82,053,566
Ensembl chr10:82,036,042...82,053,557
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G |
Otub2 |
OTU deubiquitinase, ubiquitin aldehyde binding 2 |
multiple interactions decreases expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of OTUB2 mRNA Raloxifene Hydrochloride results in decreased expression of OTUB2 mRNA |
CTD |
PMID:19059307 PMID:33269387 |
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NCBI chr 6:122,545,067...122,563,657
Ensembl chr 6:122,545,061...122,563,644
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G |
Otud1 |
OTU deubiquitinase 1 |
multiple interactions |
ISO |
[SOD1 protein mutant form affects the susceptibility to Raloxifene Hydrochloride] which results in increased expression of OTUD1 mRNA |
CTD |
PMID:33269387 |
|
NCBI chr17:82,259,920...82,262,770
Ensembl chr17:82,259,840...82,262,995
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G |
Otud3 |
OTU deubiquitinase 3 |
decreases expression multiple interactions |
ISO |
Raloxifene Hydrochloride results in decreased expression of OTUD3 mRNA [SOD1 protein mutant form affects the susceptibility to Raloxifene Hydrochloride] which results in decreased expression of OTUD3 mRNA |
CTD |
PMID:33269387 |
|
NCBI chr 5:151,135,826...151,162,207
Ensembl chr 5:151,140,059...151,163,560
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G |
Otud5 |
OTU deubiquitinase 5 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of OTUD5 mRNA |
CTD |
PMID:33269387 |
|
NCBI chr X:14,626,173...14,659,331
Ensembl chr X:14,626,164...14,659,573
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G |
Otud7a |
OTU deubiquitinase 7A |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of OTUD7A mRNA |
CTD |
PMID:33269387 |
|
NCBI chr 1:117,064,428...117,388,217
Ensembl chr 1:117,064,496...117,386,480
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G |
Otud7b |
OTU deubiquitinase 7B |
multiple interactions increases expression |
ISO |
[SOD1 protein mutant form affects the susceptibility to Raloxifene Hydrochloride] which results in increased expression of OTUD7B mRNA Raloxifene Hydrochloride results in increased expression of OTUD7B mRNA |
CTD |
PMID:33269387 |
|
NCBI chr 2:183,661,955...183,722,584
Ensembl chr 2:183,662,163...183,718,674
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G |
P2ry14 |
purinergic receptor P2Y14 |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of P2RY14 mRNA] |
CTD |
PMID:18367319 |
|
NCBI chr 2:143,372,697...143,413,213
Ensembl chr 2:143,372,697...143,413,141
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G |
Palld |
palladin, cytoskeletal associated protein |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of PALLD mRNA |
CTD |
PMID:14699072 |
|
NCBI chr16:28,228,006...28,621,349
Ensembl chr16:27,981,354...28,621,337
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G |
Papola |
poly (A) polymerase alpha |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of PAPOLA mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 6:124,682,015...124,734,706
Ensembl chr 6:124,682,105...124,734,468
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G |
Pappa |
pappalysin |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of PAPPA mRNA |
CTD |
PMID:19429434 |
|
NCBI chr 5:78,497,660...78,735,873
Ensembl chr 5:78,498,300...78,730,666
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G |
Park7 |
Parkinsonism associated deglycase |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of PARK7 mRNA |
CTD |
PMID:33269387 |
|
NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
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G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
increases cleavage multiple interactions |
ISO |
Raloxifene Hydrochloride results in increased cleavage of PARP1 protein [ESR1 protein co-treated with ESR2 protein] affects the reaction [Raloxifene Hydrochloride results in increased cleavage of PARP1 protein] |
CTD |
PMID:22965848 |
|
NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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G |
Pawr |
pro-apoptotic WT1 regulator |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of PAWR mRNA; Raloxifene Hydrochloride results in increased expression of PAWR protein |
CTD |
PMID:20945400 |
|
NCBI chr 7:43,645,028...43,725,033
Ensembl chr 7:43,645,084...43,725,028
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G |
Pax5 |
paired box 5 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of PAX5 mRNA |
CTD |
PMID:12154049 |
|
NCBI chr 5:58,763,334...58,945,719
Ensembl chr 5:58,765,036...58,944,326
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G |
Pcdh7 |
protocadherin 7 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of PCDH7 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr14:52,471,801...52,901,696
Ensembl chr14:52,475,610...52,902,051 Ensembl chr14:52,475,610...52,902,051
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G |
Pcdhga3 |
protocadherin gamma subfamily A, 3 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of PCDHGA3 mRNA |
CTD |
PMID:19429434 |
|
NCBI chr18:29,499,148...29,667,865
Ensembl chr18:29,493,954...29,667,868
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G |
Pclaf |
PCNA clamp associated factor |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of PCLAF mRNA |
CTD |
PMID:16514628 |
|
NCBI chr 8:66,420,606...66,432,994
Ensembl chr 8:66,420,587...66,432,994 Ensembl chr 8:66,420,587...66,432,994
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G |
Pcna |
proliferating cell nuclear antigen |
increases expression decreases expression affects expression multiple interactions |
ISO EXP |
Raloxifene Hydrochloride results in increased expression of PCNA protein Raloxifene Hydrochloride results in decreased expression of PCNA protein Raloxifene Hydrochloride affects the expression of PCNA protein [APC protein affects the susceptibility to Raloxifene Hydrochloride] which affects the expression of PCNA protein |
CTD |
PMID:15731164 PMID:16009171 PMID:17220163 PMID:24431404 |
|
NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
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G |
Pcolce |
procollagen C-endopeptidase enhancer |
affects expression increases expression |
EXP |
Raloxifene Hydrochloride affects the expression of PCOLCE mRNA Raloxifene Hydrochloride results in increased expression of PCOLCE mRNA |
CTD |
PMID:15576828 PMID:16079270 |
|
NCBI chr12:19,084,191...19,090,508
Ensembl chr12:19,084,210...19,090,508
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G |
Pctp |
phosphatidylcholine transfer protein |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PCTP mRNA |
CTD |
PMID:19059307 |
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NCBI chr10:74,808,887...74,856,260
Ensembl chr10:74,808,887...74,849,867
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G |
Pdcd5 |
programmed cell death 5 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of PDCD5 mRNA |
CTD |
PMID:16202921 |
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NCBI chr 1:88,305,869...88,311,200
Ensembl chr 1:88,305,869...88,311,200
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Pde3b |
phosphodiesterase 3B |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of PDE3B mRNA |
CTD |
PMID:19429434 |
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NCBI chr 1:168,606,762...168,770,078
Ensembl chr 1:168,607,022...168,769,334
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Pde4d |
phosphodiesterase 4D |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of PDE4D mRNA |
CTD |
PMID:16497877 |
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NCBI chr 2:40,014,933...41,529,190
Ensembl chr 2:40,019,933...41,525,884
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Pde5a |
phosphodiesterase 5A |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of PDE5A mRNA |
CTD |
PMID:19429434 |
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NCBI chr 2:210,858,515...211,003,480
Ensembl chr 2:210,858,063...210,999,701
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Pdgfra |
platelet derived growth factor receptor alpha |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of PDGFRA mRNA |
CTD |
PMID:14699072 |
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NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335
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G |
Pdgfrb |
platelet derived growth factor receptor beta |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of PDGFRB mRNA |
CTD |
PMID:14699072 |
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NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843
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G |
Pdlim3 |
PDZ and LIM domain 3 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PDLIM3 mRNA |
CTD |
PMID:19059307 |
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NCBI chr16:46,352,460...46,383,680
Ensembl chr16:46,352,467...46,383,657
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G |
Pdp1 |
pyruvate dehydrogenase phosphatase catalytic subunit 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of PDP1 mRNA |
CTD |
PMID:19059307 |
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NCBI chr 5:25,446,843...25,455,107
Ensembl chr 5:25,446,272...25,455,217
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G |
Pdyn |
prodynorphin |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of PDYN mRNA |
CTD |
PMID:16079270 |
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NCBI chr 3:116,900,990...116,913,334
Ensembl chr 3:116,900,992...116,913,334
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G |
Pdzk1 |
PDZ domain containing 1 |
multiple interactions decreases expression |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of PDZK1 mRNA] Raloxifene Hydrochloride results in decreased expression of PDZK1 mRNA |
CTD |
PMID:21185374 PMID:26865669 |
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NCBI chr 2:184,376,161...184,407,514
Ensembl chr 2:184,376,161...184,407,514
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G |
Per2 |
period circadian regulator 2 |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in decreased expression of PER2 mRNA] |
CTD |
PMID:18728223 |
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NCBI chr 9:92,007,289...92,049,551
Ensembl chr 9:92,007,296...92,049,459
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G |
Pex5 |
peroxisomal biogenesis factor 5 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of PEX5 mRNA |
CTD |
PMID:16079270 |
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NCBI chr 4:157,270,671...157,296,432
Ensembl chr 4:157,270,672...157,296,431
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G |
Pfkfb3 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of PFKFB3 mRNA |
CTD |
PMID:19059307 |
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NCBI chr17:66,983,629...67,064,702
Ensembl chr17:66,983,686...67,063,125
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G |
Pgr |
progesterone receptor |
multiple interactions increases expression decreases expression |
ISO EXP |
[Raloxifene Hydrochloride co-treated with Estradiol] results in increased expression of PGR mRNA; [trichostatin A co-treated with Raloxifene Hydrochloride] results in decreased expression of PGR mRNA; Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of PGR mRNA]; trichostatin A inhibits the reaction [[Raloxifene Hydrochloride co-treated with Estradiol] results in increased expression of PGR mRNA] Raloxifene Hydrochloride results in increased expression of PGR protein Raloxifene Hydrochloride results in decreased expression of PGR mRNA; Raloxifene Hydrochloride results in decreased expression of PGR protein [Estradiol co-treated with Raloxifene Hydrochloride] results in increased expression of PGR mRNA; Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of PGR mRNA] |
CTD |
PMID:11867264 PMID:16837883 PMID:16973256 PMID:21185374 PMID:22476901 PMID:26865669 PMID:26879975 More...
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NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
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G |
Phc2 |
polyhomeotic homolog 2 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PHC2 mRNA |
CTD |
PMID:19059307 |
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NCBI chr 5:141,000,604...141,099,268
Ensembl chr 5:141,050,842...141,099,268
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G |
Phf11 |
PHD finger protein 11 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PHF11 mRNA |
CTD |
PMID:19059307 |
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NCBI chr15:33,390,290...33,414,647
Ensembl chr15:33,390,292...33,413,009
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G |
Phlpp1 |
PH domain and leucine rich repeat protein phosphatase 1 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of PHLPP mRNA |
CTD |
PMID:16079270 |
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NCBI chr13:22,308,532...22,530,978
Ensembl chr13:22,308,548...22,530,977
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G |
Pias3 |
protein inhibitor of activated STAT, 3 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of PIAS3 mRNA |
CTD |
PMID:16079270 |
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NCBI chr 2:184,232,546...184,241,455
Ensembl chr 2:184,232,571...184,241,480
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G |
Pign |
phosphatidylinositol glycan anchor biosynthesis, class N |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of PIGN mRNA |
CTD |
PMID:22841776 |
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NCBI chr13:21,659,092...21,812,932
Ensembl chr13:21,662,455...21,806,790
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G |
Pigr |
polymeric immunoglobulin receptor |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of PIGR mRNA |
CTD |
PMID:16079270 |
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NCBI chr13:42,298,905...42,326,877
Ensembl chr13:42,298,914...42,326,875
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G |
Pik3r3 |
phosphoinositide-3-kinase regulatory subunit 3 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of PIK3R3 mRNA |
CTD |
PMID:26865669 |
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NCBI chr 5:129,700,925...129,772,591
Ensembl chr 5:129,701,229...129,772,583
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G |
Pim1 |
Pim-1 proto-oncogene, serine/threonine kinase |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of PIM1 mRNA |
CTD |
PMID:14699072 |
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NCBI chr20:7,554,921...7,559,174
Ensembl chr20:7,554,921...7,559,174
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G |
Pitpnc1 |
phosphatidylinositol transfer protein, cytoplasmic 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PITPNC1 mRNA |
CTD |
PMID:19059307 |
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NCBI chr10:92,163,558...92,428,971
Ensembl chr10:92,167,196...92,429,297
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G |
Pla2g10 |
phospholipase A2, group X |
multiple interactions |
ISO |
Raloxifene Hydrochloride promotes the reaction [Estradiol results in increased expression of PLA2G10 mRNA] |
CTD |
PMID:21185374 |
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NCBI chr10:1,597,761...1,610,822
Ensembl chr10:1,597,761...1,609,000
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G |
Pla2g7 |
phospholipase A2 group VII |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of PLA2G7 mRNA |
CTD |
PMID:19429434 |
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NCBI chr 9:17,362,214...17,404,476
Ensembl chr 9:17,362,225...17,404,476
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G |
Plat |
plasminogen activator, tissue type |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of PLAT protein |
CTD |
PMID:16167916 |
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NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
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G |
Plau |
plasminogen activator, urokinase |
multiple interactions decreases expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of PLAU mRNA Raloxifene Hydrochloride results in decreased expression of PLAU protein |
CTD |
PMID:16277677 PMID:19059307 |
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NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
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G |
Plaur |
plasminogen activator, urokinase receptor |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of PLAUR mRNA; Raloxifene Hydrochloride results in decreased expression of PLAUR protein |
CTD |
PMID:16277677 PMID:26865669 |
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NCBI chr 1:80,053,440...80,068,384
Ensembl chr 1:80,050,324...80,068,595
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G |
Plekhf2 |
pleckstrin homology and FYVE domain containing 2 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of PLEKHF2 mRNA |
CTD |
PMID:26865669 |
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NCBI chr 5:24,091,077...24,106,758
Ensembl chr 5:24,090,688...24,106,601
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G |
Plekhs1 |
pleckstrin homology domain containing S1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with Estradiol] results in increased expression of PLEKHS1 mRNA |
CTD |
PMID:21185374 |
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NCBI chr 1:255,495,634...255,525,353
Ensembl chr 1:255,495,634...255,525,353
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G |
Plk3 |
polo-like kinase 3 |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased expression of PLK3 mRNA] |
CTD |
PMID:12072388 |
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NCBI chr 5:130,607,142...130,612,317
Ensembl chr 5:130,607,142...130,612,317
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G |
Plpp1 |
phospholipid phosphatase 1 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of PLPP1 mRNA |
CTD |
PMID:16079270 |
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NCBI chr 2:44,439,002...44,500,430
Ensembl chr 2:44,438,994...44,501,268
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G |
Plpp3 |
phospholipid phosphatase 3 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of PLPP3 mRNA ESR1 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of PLPP3 mRNA] |
CTD |
PMID:14699072 |
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NCBI chr 5:119,927,085...120,002,206
Ensembl chr 5:119,927,085...120,002,205
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G |
Plxnd1 |
plexin D1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of PLXND1 mRNA |
CTD |
PMID:19429434 |
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NCBI chr 4:149,002,786...149,043,097
Ensembl chr 4:149,002,784...149,043,244
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G |
Pmaip1 |
phorbol-12-myristate-13-acetate-induced protein 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of PMAIP1 mRNA |
CTD |
PMID:16497877 |
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NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429
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G |
Pmp22 |
peripheral myelin protein 22 |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in decreased expression of PMP22 mRNA] |
CTD |
PMID:21185374 |
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NCBI chr10:47,795,709...47,825,715
Ensembl chr10:47,795,709...47,825,714
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G |
Pms2 |
PMS1 homolog 2, mismatch repair system component |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of PMS2 mRNA |
CTD |
PMID:16202921 |
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NCBI chr12:10,676,818...10,701,161
Ensembl chr12:10,676,764...10,701,066
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G |
Podxl |
podocalyxin-like |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of PODXL mRNA |
CTD |
PMID:14699072 |
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NCBI chr 4:60,135,124...60,181,829
Ensembl chr 4:60,135,109...60,181,899
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G |
Polm |
DNA polymerase mu |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of POLM mRNA |
CTD |
PMID:16497877 |
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NCBI chr14:80,707,075...80,716,677
Ensembl chr14:80,706,345...80,717,086
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G |
Polr2b |
RNA polymerase II subunit B |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of POLR2B mRNA |
CTD |
PMID:16514628 |
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NCBI chr14:30,797,228...30,834,916
Ensembl chr14:30,797,228...30,834,916
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G |
Postn |
periostin |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of POSTN mRNA; Raloxifene Hydrochloride results in decreased expression of POSTN protein |
CTD |
PMID:32947957 |
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NCBI chr 2:138,527,714...138,559,098
Ensembl chr 2:138,527,696...138,559,099
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
multiple interactions |
ISO |
IWR-1 compound inhibits the reaction [Raloxifene Hydrochloride inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of PPARG protein]]; Raloxifene Hydrochloride inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of PPARG protein] |
CTD |
PMID:31470850 |
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NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G |
Ppm1d |
protein phosphatase, Mg2+/Mn2+ dependent, 1D |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of PPM1D mRNA |
CTD |
PMID:16514628 |
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NCBI chr10:70,172,603...70,208,607
Ensembl chr10:70,172,603...70,208,607
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G |
Ppp1r10 |
protein phosphatase 1, regulatory subunit 10 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of PPP1R10 mRNA |
CTD |
PMID:16497877 |
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NCBI chr20:2,822,995...2,838,125
Ensembl chr20:2,822,995...2,837,611
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G |
Ppp1r13b |
protein phosphatase 1, regulatory subunit 13B |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of PPP1R13B mRNA |
CTD |
PMID:16202921 |
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NCBI chr 6:130,890,682...130,963,845
Ensembl chr 6:130,890,679...130,963,330
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G |
Ppp1r15a |
protein phosphatase 1, regulatory subunit 15A |
increases expression affects expression |
ISO EXP |
Raloxifene Hydrochloride results in increased expression of PPP1R15A mRNA Raloxifene Hydrochloride affects the expression of PPP1R15A mRNA |
CTD |
PMID:16079270 |