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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:pyrimidine antifungal drug
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Accession:CHEBI:87205 term browser browse the term
Definition:Any pyrimidine antifungal agent that has been used for the treatment of fungal infections in humans or animals.
Synonyms:related_synonym: pyrimidine antifungal drugs


show annotations for term's descendants           Sort by:
flucytosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL2 BCL2 apoptosis regulator decreases expression EXP Flucytosine results in decreased expression of BCL2 protein CTD PMID:15592511 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G MDM2 MDM2 proto-oncogene increases expression EXP Flucytosine results in increased expression of MDM2 protein CTD PMID:15592511 NCBI chr12:68,808,172...68,850,686
Ensembl chr12:68,808,177...68,845,544 		JBrowse link
G TP53 tumor protein p53 increases expression EXP Flucytosine results in increased expression of TP53 protein CTD PMID:15592511 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26496
    role 26318
      biological role 26297
        antimicrobial agent 22506
          antifungal agent 20571
            antifungal drug 6637
              pyrimidine antifungal drug 3
                flucytosine 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 26496
    subatomic particle 26472
      composite particle 26472
        hadron 26472
          baryon 26472
            nucleon 26472
              atomic nucleus 26472
                atom 26472
                  main group element atom 26209
                    p-block element atom 26209
                      carbon group element atom 25654
                        carbon atom 25616
                          organic molecular entity 25616
                            organic molecule 25360
                              organic cyclic compound 24412
                                organic heterocyclic compound 22419
                                  organic heteromonocyclic compound 19242
                                    diazines 13365
                                      pyrimidines 13211
                                        pyrimidine antifungal agent 82
                                          pyrimidine antifungal drug 3
                                            flucytosine 3
paths to the root