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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:bridged diphenyl antifungal drug
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Accession:CHEBI:87110 term browser browse the term
Definition:Any bridged diphenyl antifungal agent used for the treatment of fungal infections in humans or animals.


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bithionol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Iyd iodotyrosine deiodinase multiple interactions ISO Bithionol inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] CTD PMID:33352258 NCBI chr10:3,490,274...3,504,880
Ensembl chr10:3,490,240...3,504,877 		JBrowse link
G Slc22a2 solute carrier family 22 (organic cation transporter), member 2 multiple interactions ISO Bithionol inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr17:12,803,076...12,847,376
Ensembl chr17:12,803,019...12,847,375 		JBrowse link
G Thra thyroid hormone receptor alpha increases activity ISO Bithionol results in increased activity of THRA protein CTD PMID:22015988 NCBI chr11:98,631,539...98,659,832
Ensembl chr11:98,631,464...98,659,832 		JBrowse link
G Thrb thyroid hormone receptor beta increases activity ISO Bithionol results in increased activity of THRB protein CTD PMID:22015988 NCBI chr14:4,429,599...4,810,538
Ensembl chr14:4,431,611...4,809,435 		JBrowse link
G Trp53 transformation related protein 53 affects activity ISO Bithionol affects the activity of TP53 protein CTD PMID:35435491 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
fenticlor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trp53 transformation related protein 53 affects activity ISO fentichlor affects the activity of TP53 protein CTD PMID:35435491 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22307
    role 22292
      biological role 22291
        antimicrobial agent 19678
          antifungal agent 18054
            bridged diphenyl antifungal agent 1317
              bridged diphenyl antifungal drug 5
                bithionol 5
                fenticlor 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 22307
    subatomic particle 22302
      composite particle 22302
        hadron 22302
          baryon 22302
            nucleon 22302
              atomic nucleus 22302
                atom 22302
                  main group element atom 22182
                    p-block element atom 22182
                      p-block molecular entity 22182
                        carbon group molecular entity 21984
                          organic molecular entity 21924
                            organic molecule 21750
                              organic cyclic compound 21366
                                organic aromatic compound 20853
                                  bridged diphenyl antifungal agent 1317
                                    bridged diphenyl antifungal drug 5
                                      bithionol 5
                                      fenticlor 1
paths to the root