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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:bridged diphenyl antifungal drug
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Accession:CHEBI:87110 term browser browse the term
Definition:Any bridged diphenyl antifungal agent used for the treatment of fungal infections in humans or animals.


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bithionol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IYD iodotyrosine deiodinase multiple interactions EXP Bithionol inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] CTD PMID:33352258 NCBI chr 6:150,369,012...150,405,969
Ensembl chr 6:150,368,892...150,405,969 		JBrowse link
G SLC22A2 solute carrier family 22 member 2 multiple interactions EXP Bithionol inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 6:160,216,755...160,258,821
Ensembl chr 6:160,171,061...160,277,638 		JBrowse link
G THRA thyroid hormone receptor alpha increases activity ISO Bithionol results in increased activity of THRA protein CTD PMID:22015988 NCBI chr17:40,062,193...40,093,867
Ensembl chr17:40,058,290...40,093,867 		JBrowse link
G THRB thyroid hormone receptor beta increases activity ISO Bithionol results in increased activity of THRB protein CTD PMID:22015988 NCBI chr 3:24,117,153...24,495,708
Ensembl chr 3:24,117,153...24,495,756 		JBrowse link
G TP53 tumor protein p53 affects activity EXP Bithionol affects the activity of TP53 protein CTD PMID:35435491 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
fenticlor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TP53 tumor protein p53 affects activity EXP fentichlor affects the activity of TP53 protein CTD PMID:35435491 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26496
    role 26318
      biological role 26297
        antimicrobial agent 22506
          antifungal agent 20571
            bridged diphenyl antifungal agent 1281
              bridged diphenyl antifungal drug 5
                bithionol 5
                fenticlor 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 26496
    subatomic particle 26472
      composite particle 26472
        hadron 26472
          baryon 26472
            nucleon 26472
              atomic nucleus 26472
                atom 26472
                  main group element atom 26209
                    p-block element atom 26209
                      p-block molecular entity 26204
                        carbon group molecular entity 25654
                          organic molecular entity 25616
                            organic molecule 25360
                              organic cyclic compound 24412
                                organic aromatic compound 24006
                                  bridged diphenyl antifungal agent 1281
                                    bridged diphenyl antifungal drug 5
                                      bithionol 5
                                      fenticlor 1
paths to the root