CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: anilide fungicide
Accession: CHEBI:87015
browse the term
Definition: Any amide fungicide whose structure contains an anilide group.
Synonyms: related_synonym: anilide fungicides
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Atf3
activating transcription factor 3
increases expression
ISO
3,3',4',5-tetrachlorosalicylanilide results in increased expression of ATF3 mRNA
CTD
PMID:27965148
NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
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Dnajb4
DnaJ heat shock protein family (Hsp40) member B4
increases expression
ISO
3,3',4',5-tetrachlorosalicylanilide results in increased expression of DNAJB4 mRNA
CTD
PMID:27965148
NCBI chr 2:241,129,346...241,159,272
Ensembl chr 2:241,130,340...241,159,089
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Iyd
iodotyrosine deiodinase
multiple interactions
ISO
3,3',4',5-tetrachlorosalicylanilide inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine]
CTD
PMID:33352258
NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319
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Slc22a2
solute carrier family 22 member 2
multiple interactions
ISO
3,3',4',5-tetrachlorosalicylanilide inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium]
CTD
PMID:21599003
NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
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Anxa2
annexin A2
decreases expression
ISO
Carboxin results in decreased expression of ANXA2 mRNA
CTD
PMID:33512557
NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
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Bbc3
Bcl-2 binding component 3
decreases expression
ISO
Carboxin results in decreased expression of BBC3 mRNA
CTD
PMID:33512557
NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
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Anxa10
annexin A10
increases expression
ISO
N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of ANXA10 mRNA
CTD
PMID:32194361
NCBI chr16:27,738,712...27,805,648
Ensembl chr16:27,738,712...27,805,648
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Ar
androgen receptor
multiple interactions affects binding
ISO
N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA] N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide binds to AR protein
CTD
PMID:21310686 PMID:23436777
NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
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Arg1
arginase 1
decreases expression
ISO
N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in decreased expression of ARG1 mRNA
CTD
PMID:32194361
NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
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Atm
ATM serine/threonine kinase
increases expression
ISO
N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of ATM mRNA
CTD
PMID:25461557
NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
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Bax
BCL2 associated X, apoptosis regulator
multiple interactions decreases expression
ISO
2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in decreased expression of BAX protein]; [Fulvestrant co-treated with 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine] inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in decreased expression of BAX protein]; Fulvestrant inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in decreased expression of BAX protein]
CTD
PMID:33484789
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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Bcl2
BCL2, apoptosis regulator
multiple interactions increases expression decreases expression
ISO
MIR21 mRNA mutant form inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in decreased expression of BCL2 protein] N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of BCL2 mRNA; N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of BCL2 protein
CTD
PMID:23052036 PMID:33484789
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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Birc5
baculoviral IAP repeat-containing 5
increases expression multiple interactions
ISO
N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of BIRC5 protein 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of BIRC5 protein]; 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine promotes the reaction [Fulvestrant inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of BIRC5 protein]]; Fulvestrant inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of BIRC5 protein]; Fulvestrant promotes the reaction [2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of BIRC5 protein]]
CTD
PMID:33484789
NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
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Casp9
caspase 9
multiple interactions
ISO
[N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide co-treated with Fulvestrant co-treated with 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine] results in increased cleavage of CASP9 protein
CTD
PMID:33484789
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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Ccnd1
cyclin D1
multiple interactions increases expression decreases expression
ISO
ESR1 protein affects the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in decreased expression of CCND1 mRNA]; fulvestrant inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of CCND1 protein] N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of CCND1 mRNA; N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of CCND1 protein
CTD
PMID:23052036 PMID:23436777 PMID:26344002 PMID:33484789
NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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Ccne1
cyclin E1
multiple interactions increases expression
ISO
[2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine co-treated with Fulvestrant] inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of CCNE1 protein]; Fulvestrant inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of CCNE1 protein]
CTD
PMID:26344002 PMID:33484789
NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
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Cdc25a
cell division cycle 25A
increases expression
ISO
N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of CDC25A mRNA
CTD
PMID:25461557
NCBI chr 8:109,864,356...109,882,734
Ensembl chr 8:109,864,478...109,882,701
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Col18a1
collagen type XVIII alpha 1 chain
multiple interactions
ISO
[systhane co-treated with N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide] results in decreased expression of COL18A1 mRNA
CTD
PMID:25461557
NCBI chr20:11,474,104...11,582,593
Ensembl chr20:11,474,104...11,582,593
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Ctsd
cathepsin D
multiple interactions increases expression
ISO
fulvestrant inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of CTSD protein]
CTD
PMID:26344002
NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
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Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
decreases expression
ISO
N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in decreased expression of CYP1A1 mRNA
CTD
PMID:32194361
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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Cyp2c6
cytochrome P450, family 2, subfamily C, polypeptide 6
decreases expression
ISO
N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in decreased expression of CYP2C19 protein
CTD
PMID:32194361
NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
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Cyp3a2
cytochrome P450, family 3, subfamily a, polypeptide 2
multiple interactions
ISO
[N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide co-treated with pyrimethanil co-treated with Fenitrothion co-treated with triadimefon co-treated with quinoxyfen co-treated with penconazole] results in increased expression of CYP3A4 mRNA
CTD
PMID:25028461
NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
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Cyp7a1
cytochrome P450 family 7 subfamily A member 1
decreases expression
ISO
N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in decreased expression of CYP7A1 mRNA
CTD
PMID:32194361
NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
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Esr1
estrogen receptor 1
multiple interactions increases activity decreases expression
ISO
[fludioxonil co-treated with N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide co-treated with Chlorpyrifos] results in increased activity of ESR1 protein; [fludioxonil co-treated with N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide co-treated with propamocarb] results in increased activity of ESR1 protein; [fludioxonil co-treated with N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide] results in increased activity of ESR1 protein; ESR1 protein affects the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in decreased expression of CCND1 mRNA]; N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide binds to and results in increased activity of ESR1 protein; N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide inhibits the reaction [Estradiol results in increased activity of ESR1 protein]; Tamoxifen inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased activity of ESR1 protein] N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in decreased expression of ESR1 mRNA
CTD
PMID:20143881 PMID:23052036 PMID:23436777 PMID:26812056
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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Esr2
estrogen receptor 2
multiple interactions increases expression increases activity
ISO
[fludioxonil co-treated with N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide co-treated with propamocarb] results in increased activity of ESR2 protein; [fludioxonil co-treated with N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide] results in increased activity of ESR2 protein; N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide inhibits the reaction [Estradiol results in increased expression of ESR2 mRNA] N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of ESR2 mRNA N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased activity of ESR2 protein
CTD
PMID:23436777 PMID:26812056
NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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Ets2
ETS proto-oncogene 2, transcription factor
multiple interactions
ISO
[systhane co-treated with N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide] results in decreased expression of ETS2 mRNA
CTD
PMID:25461557
NCBI chr11:35,021,536...35,038,322
Ensembl chr11:35,021,596...35,038,319
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Itga4
integrin subunit alpha 4
increases expression
ISO
N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of ITGA4 mRNA
CTD
PMID:25461557
NCBI chr 3:64,162,764...64,235,010
Ensembl chr 3:64,163,085...64,233,715
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Itgav
integrin subunit alpha V
increases expression
ISO
N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of ITGAV mRNA
CTD
PMID:25461557
NCBI chr 3:68,838,514...68,926,653
Ensembl chr 3:68,838,189...68,926,639
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Itgb1
integrin subunit beta 1
multiple interactions
ISO
[systhane co-treated with N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide] results in decreased expression of ITGB1 mRNA
CTD
PMID:25461557
NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
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Mir200a
microRNA 200a
increases expression
ISO
N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of MIR200A mRNA
CTD
PMID:23052036
NCBI chr 5:166,648,494...166,648,582
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Mir21
microRNA 21
multiple interactions increases expression
ISO
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of MIR21 mRNA]; bicalutamide inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of MIR21 mRNA]; Cycloheximide inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of MIR21 mRNA]; Dactinomycin inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of MIR21 mRNA]; fulvestrant inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of MIR21 mRNA]; MIR21 mRNA mutant form inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in decreased expression of BCL2 protein]; MIR21 mRNA mutant form inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in decreased expression of PDCD4 protein]; wortmannin inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of MIR21 mRNA]
CTD
PMID:23052036
NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
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Mir22
microRNA 22
increases expression
ISO
N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of MIR22 mRNA
CTD
PMID:23052036
NCBI chr10:60,307,039...60,307,133
Ensembl chr10:60,307,039...60,307,133
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Nr1i2
nuclear receptor subfamily 1, group I, member 2
multiple interactions
ISO
[N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide co-treated with pyrimethanil co-treated with Fenitrothion co-treated with triadimefon co-treated with quinoxyfen co-treated with penconazole] results in increased activity of NR1I2 protein
CTD
PMID:25028461
NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
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Pcna
proliferating cell nuclear antigen
multiple interactions increases expression
ISO
2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of PCNA protein]; 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine promotes the reaction [Fulvestrant inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of PCNA protein]]; Fulvestrant inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of PCNA protein]; Fulvestrant promotes the reaction [2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of PCNA protein]]
CTD
PMID:33484789
NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
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Pdcd4
programmed cell death 4
multiple interactions decreases expression
ISO
MIR21 mRNA mutant form inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in decreased expression of PDCD4 protein] N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in decreased expression of PDCD4 mRNA; N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in decreased expression of PDCD4 protein
CTD
PMID:23052036
NCBI chr 1:252,921,342...252,944,278
Ensembl chr 1:252,921,392...252,944,275
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Pdgfa
platelet derived growth factor subunit A
increases expression multiple interactions
ISO
N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of PDGFA mRNA [systhane co-treated with N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide] results in increased expression of PDGFA mRNA
CTD
PMID:25461557
NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
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Pdgfb
platelet derived growth factor subunit B
multiple interactions
ISO
[systhane co-treated with N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide] results in decreased expression of PDGFB mRNA
CTD
PMID:25461557
NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
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Pgr
progesterone receptor
decreases expression affects binding increases expression
ISO
N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in decreased expression of PGR mRNA N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide binds to PGR protein N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of PGR mRNA
CTD
PMID:23052036 PMID:23436777 PMID:32278787
NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
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Pten
phosphatase and tensin homolog
decreases expression
ISO
N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in decreased expression of PTEN mRNA
CTD
PMID:23052036
NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
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Ptgs2
prostaglandin-endoperoxide synthase 2
multiple interactions
ISO
[N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide binds to and results in decreased activity of PTGS2 protein] which results in decreased chemical synthesis of and results in decreased secretion of Prostaglandin D2
CTD
PMID:26359731
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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Rarb
retinoic acid receptor, beta
multiple interactions decreases expression
ISO
N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide promotes the reaction [Estradiol results in decreased expression of RARB mRNA] N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in decreased expression of RARB mRNA
CTD
PMID:23436777
NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288
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Rb1
RB transcriptional corepressor 1
increases expression multiple interactions
ISO
N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of RB1 mRNA [systhane co-treated with N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide] affects the expression of RB1 mRNA
CTD
PMID:25461557
NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
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Timp1
TIMP metallopeptidase inhibitor 1
increases expression
ISO
N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of TIMP1 mRNA
CTD
PMID:25461557
NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
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Timp3
TIMP metallopeptidase inhibitor 3
increases expression
ISO
N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of TIMP3 mRNA
CTD
PMID:25461557
NCBI chr 7:17,520,827...17,571,850
Ensembl chr 7:17,521,919...17,571,839
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Vmp1
vacuole membrane protein 1
multiple interactions increases expression
ISO
Dactinomycin inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of VMP1 mRNA]
CTD
PMID:23052036
NCBI chr10:71,405,058...71,505,045
Ensembl chr10:71,405,452...71,505,007
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Cyp3a2
cytochrome P450, family 3, subfamily a, polypeptide 2
increases expression
ISO
flutolanil results in increased expression of CYP3A4 mRNA
CTD
PMID:17293382
NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
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Esr1
estrogen receptor 1
decreases expression multiple interactions
ISO
flutolanil results in decreased expression of ESR1 protein flutolanil binds to and results in increased activity of ESR1 protein
CTD
PMID:17904202
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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Nr1i2
nuclear receptor subfamily 1, group I, member 2
multiple interactions
ISO
flutolanil binds to and results in increased activity of NR1I2 protein
CTD
PMID:21115097
NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
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Pgr
progesterone receptor
increases expression
ISO
flutolanil results in increased expression of PGR mRNA
CTD
PMID:17904202
NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
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Pparg
peroxisome proliferator-activated receptor gamma
increases activity
ISO
flutolanil results in increased activity of PPARG protein
CTD
PMID:20143881
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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Tff1
trefoil factor 1
increases expression
ISO
flutolanil results in increased expression of TFF1 mRNA
CTD
PMID:17904202
NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597
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Anxa10
annexin A10
increases expression
ISO
fluxapyroxad results in increased expression of ANXA10 mRNA
CTD
PMID:32194361
NCBI chr16:27,738,712...27,805,648
Ensembl chr16:27,738,712...27,805,648
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Arg1
arginase 1
decreases expression
ISO
fluxapyroxad results in decreased expression of ARG1 mRNA
CTD
PMID:32194361
NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
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Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
multiple interactions
ISO
[fluxapyroxad co-treated with epoxiconazole] results in increased expression of CYP1A1 mRNA; [fluxapyroxad co-treated with epoxiconazole] results in increased expression of CYP1A1 protein
CTD
PMID:29294346
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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Cyp2b3
cytochrome P450, family 2, subfamily b, polypeptide 3
increases expression multiple interactions
ISO
fluxapyroxad results in increased expression of CYP2B6 mRNA; fluxapyroxad results in increased expression of CYP2B6 protein [fluxapyroxad co-treated with epoxiconazole] results in increased expression of CYP2B6 mRNA; [fluxapyroxad co-treated with epoxiconazole] results in increased expression of CYP2B6 protein
CTD
PMID:29294346
NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
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Cyp2c6
cytochrome P450, family 2, subfamily C, polypeptide 6
decreases expression
ISO
fluxapyroxad results in decreased expression of CYP2C19 protein
CTD
PMID:32194361
NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
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Cyp3a2
cytochrome P450, family 3, subfamily a, polypeptide 2
increases expression multiple interactions
ISO
fluxapyroxad results in increased expression of CYP3A4 mRNA [fluxapyroxad co-treated with epoxiconazole] results in increased expression of CYP3A4 mRNA; [fluxapyroxad co-treated with epoxiconazole] results in increased expression of CYP3A4 protein
CTD
PMID:29294346
NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
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Cyp7a1
cytochrome P450 family 7 subfamily A member 1
decreases expression
ISO
fluxapyroxad results in decreased expression of CYP7A1 mRNA; fluxapyroxad results in decreased expression of CYP7A1 protein
CTD
PMID:32194361
NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
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G6pc1
glucose-6-phosphatase catalytic subunit 1
decreases expression
ISO
fluxapyroxad results in decreased expression of G6PC1 mRNA
CTD
PMID:32194361
NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804
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Cyp2c6
cytochrome P450, family 2, subfamily C, polypeptide 6
decreases expression
ISO
metalaxyl results in decreased expression of CYP2C19 protein
CTD
PMID:32194361
NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
G
Cyp7a1
cytochrome P450 family 7 subfamily A member 1
decreases expression
ISO
metalaxyl results in decreased expression of CYP7A1 protein
CTD
PMID:32194361
NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
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Tp53
tumor protein p53
affects activity
ISO
oxycarboxin affects the activity of TP53 protein
CTD
PMID:35435491
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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Aars1
alanyl-tRNA synthetase 1
increases expression
ISO
thifluzamide results in increased expression of AARS1 mRNA
CTD
PMID:33512557
NCBI chr19:38,999,130...39,021,152
Ensembl chr19:38,999,163...39,021,147
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Akt1
AKT serine/threonine kinase 1
decreases expression
ISO
thifluzamide results in decreased expression of AKT1 mRNA
CTD
PMID:33512557
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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Aldh7a1
aldehyde dehydrogenase 7 family, member A1
decreases expression
ISO
thifluzamide results in decreased expression of ALDH7A1 mRNA
CTD
PMID:33512557
NCBI chr18:50,003,242...50,042,193
Ensembl chr18:50,009,934...50,042,193
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Aldoa
aldolase, fructose-bisphosphate A
increases expression
ISO
thifluzamide results in increased expression of ALDOA mRNA
CTD
PMID:33512557
NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182
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Anxa2
annexin A2
decreases expression
ISO
thifluzamide results in decreased expression of ANXA2 mRNA
CTD
PMID:33512557
NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
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Arhgap8
Rho GTPase activating protein 8
increases expression
ISO
thifluzamide results in increased expression of ARHGAP8 mRNA
CTD
PMID:33512557
NCBI chr 7:115,842,223...115,902,094
Ensembl chr 7:115,850,654...115,902,093
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Arhgap9
Rho GTPase activating protein 9
increases expression
ISO
thifluzamide results in increased expression of ARHGAP9 mRNA
CTD
PMID:33512557
NCBI chr 7:63,148,573...63,157,025
Ensembl chr 7:63,148,900...63,157,524
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Arhgef2
Rho/Rac guanine nucleotide exchange factor 2
increases expression
ISO
thifluzamide results in increased expression of ARHGEF2 mRNA
CTD
PMID:33512557
NCBI chr 2:174,061,126...174,118,355
Ensembl chr 2:174,062,976...174,118,355
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Arid4a
AT-rich interaction domain 4A
decreases expression
ISO
thifluzamide results in decreased expression of ARID4A mRNA
CTD
PMID:33512557
NCBI chr 6:89,522,459...89,593,868
Ensembl chr 6:89,522,442...89,593,510
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Arrdc4
arrestin domain containing 4
decreases expression
ISO
thifluzamide results in decreased expression of ARRDC4 mRNA
CTD
PMID:33512557
NCBI chr 1:122,369,355...122,383,351
Ensembl chr 1:122,369,360...122,383,290
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Arsg
arylsulfatase G
increases expression
ISO
thifluzamide results in increased expression of ARSG mRNA
CTD
PMID:33512557
NCBI chr10:94,412,261...94,551,224
Ensembl chr10:94,447,399...94,542,941
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Asns
asparagine synthetase (glutamine-hydrolyzing)
increases expression
ISO
thifluzamide results in increased expression of ASNS mRNA
CTD
PMID:33512557
NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
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Ass1
argininosuccinate synthase 1
increases expression
ISO
thifluzamide results in increased expression of ASS1 mRNA
CTD
PMID:33512557
NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903
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Atf4
activating transcription factor 4
increases expression
ISO
thifluzamide results in increased expression of ATF4 mRNA
CTD
PMID:33512557
NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
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Atf5
activating transcription factor 5
increases expression
ISO
thifluzamide results in increased expression of ATF5 mRNA
CTD
PMID:33512557
NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:95,295,610...95,299,707
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Aurkb
aurora kinase B
increases expression
ISO
thifluzamide results in increased expression of AURKB mRNA
CTD
PMID:33512557
NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837
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Bid
BH3 interacting domain death agonist
decreases expression
ISO
thifluzamide results in decreased expression of BID mRNA
CTD
PMID:33512557
NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
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Birc2
baculoviral IAP repeat-containing 2
decreases expression
ISO
thifluzamide results in decreased expression of BIRC2 mRNA
CTD
PMID:33512557
NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732
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Birc5
baculoviral IAP repeat-containing 5
increases expression
ISO
thifluzamide results in increased expression of BIRC5 mRNA
CTD
PMID:33512557
NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
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Bmf
Bcl2 modifying factor
decreases expression
ISO
thifluzamide results in decreased expression of BMF mRNA
CTD
PMID:33512557
NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145
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Bphl
biphenyl hydrolase like
decreases expression
ISO
thifluzamide results in decreased expression of BPHL mRNA
CTD
PMID:33512557
NCBI chr17:30,800,939...30,837,277
Ensembl chr17:30,799,629...30,837,288
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Bsg
basigin
increases expression
ISO
thifluzamide results in increased expression of BSG mRNA
CTD
PMID:33512557
NCBI chr 7:9,993,170...10,000,387
Ensembl chr 7:9,993,170...10,000,387
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C1d
C1D nuclear receptor corepressor
increases expression
ISO
thifluzamide results in increased expression of C1D mRNA
CTD
PMID:33512557
NCBI chr14:91,660,951...91,673,177
Ensembl chr14:91,660,989...91,672,852
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C2cd5
C2 calcium-dependent domain containing 5
decreases expression
ISO
thifluzamide results in decreased expression of C2CD5 mRNA
CTD
PMID:33512557
NCBI chr 4:175,969,544...176,055,597
Ensembl chr 4:175,969,545...176,055,558
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Camk2b
calcium/calmodulin-dependent protein kinase II beta
decreases expression
ISO
thifluzamide results in decreased expression of CAMK2B mRNA
CTD
PMID:33512557
NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994
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Cars1
cysteinyl-tRNA synthetase 1
increases expression
ISO
thifluzamide results in increased expression of CARS1 mRNA
CTD
PMID:33512557
NCBI chr 1:198,753,689...198,796,016
Ensembl chr 1:198,753,691...198,795,941
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Cbx4
chromobox 4
increases expression
ISO
thifluzamide results in increased expression of CBX4 mRNA
CTD
PMID:33512557
NCBI chr10:104,337,140...104,343,210
Ensembl chr10:104,336,876...104,356,706
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Ccnb2
cyclin B2
increases expression
ISO
thifluzamide results in increased expression of CCNB2 mRNA
CTD
PMID:33512557
NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
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Ccne2
cyclin E2
decreases expression
ISO
thifluzamide results in decreased expression of CCNE2 mRNA
CTD
PMID:33512557
NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632
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Cd24
CD24 molecule
decreases expression
ISO
thifluzamide results in decreased expression of CD24 mRNA
CTD
PMID:33512557
NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662
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Cdh10
cadherin 10
decreases expression
ISO
thifluzamide results in decreased expression of CDH10 mRNA
CTD
PMID:33512557
NCBI chr 2:68,628,623...68,850,995
Ensembl chr 2:68,628,780...68,850,995
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Cdk1
cyclin-dependent kinase 1
increases expression
ISO
thifluzamide results in increased expression of CDK1 mRNA
CTD
PMID:33512557
NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
G
Cdk5
cyclin-dependent kinase 5
decreases expression
ISO
thifluzamide results in decreased expression of CDK5 mRNA
CTD
PMID:33512557
NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112
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Cdkn3
cyclin-dependent kinase inhibitor 3
increases expression
ISO
thifluzamide results in increased expression of CDKN3 mRNA
CTD
PMID:33512557
NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945
G
Cebpb
CCAAT/enhancer binding protein beta
increases expression
ISO
thifluzamide results in increased expression of CEBPB mRNA
CTD
PMID:33512557
NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
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Cep55
centrosomal protein 55
increases expression
ISO
thifluzamide results in increased expression of CEP55 mRNA
CTD
PMID:33512557
NCBI chr 1:235,832,823...235,848,401
Ensembl chr 1:235,832,878...235,848,394
G
Chac1
ChaC glutathione-specific gamma-glutamylcyclotransferase 1
increases expression
ISO
thifluzamide results in increased expression of CHAC1 mRNA
CTD
PMID:33512557
NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526
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Chka
choline kinase alpha
increases expression
ISO
thifluzamide results in increased expression of CHKA mRNA
CTD
PMID:33512557
NCBI chr 1:201,076,804...201,125,517
Ensembl chr 1:201,076,860...201,125,516
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Chrna4
cholinergic receptor nicotinic alpha 4 subunit
decreases expression
ISO
thifluzamide results in decreased expression of CHRNA4 mRNA
CTD
PMID:33512557
NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957
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Cks2
CDC28 protein kinase regulatory subunit 2
increases expression
ISO
thifluzamide results in increased expression of CKS2 mRNA
CTD
PMID:33512557
NCBI chr17:13,570,611...13,575,770
G
Cldn5
claudin 5
decreases expression
ISO
thifluzamide results in decreased expression of CLDN5 mRNA
CTD
PMID:33512557
NCBI chr11:82,212,822...82,214,248
Ensembl chr11:82,211,475...82,214,992
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Clic4
chloride intracellular channel 4
increases expression
ISO
thifluzamide results in increased expression of CLIC4 mRNA
CTD
PMID:33512557
NCBI chr 5:147,453,702...147,513,455
Ensembl chr 5:147,453,712...147,513,452
G
Cpne3
copine 3
decreases expression
ISO
thifluzamide results in decreased expression of CPNE3 mRNA
CTD
PMID:33512557
NCBI chr 5:33,014,658...33,063,934
Ensembl chr 5:33,016,307...33,063,934
G
Cpsf4
cleavage and polyadenylation specific factor 4
decreases expression
ISO
thifluzamide results in decreased expression of CPSF4 mRNA
CTD
PMID:33512557
NCBI chr12:9,429,765...9,445,586
Ensembl chr12:9,429,523...9,445,586
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Creg1
cellular repressor of E1A-stimulated genes 1
increases expression
ISO
thifluzamide results in increased expression of CREG1 mRNA
CTD
PMID:33512557
NCBI chr13:78,019,814...78,032,310
Ensembl chr13:78,019,843...78,032,308
G
Crtap
cartilage associated protein
increases expression
ISO
thifluzamide results in increased expression of CRTAP mRNA
CTD
PMID:33512557
NCBI chr 8:114,047,929...114,067,636
Ensembl chr 8:114,047,933...114,067,631
G
Cth
cystathionine gamma-lyase
increases expression
ISO
thifluzamide results in increased expression of CTH mRNA
CTD
PMID:33512557
NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234
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Ctnnd1
catenin delta 1
decreases expression
ISO
thifluzamide results in decreased expression of CTNND1 mRNA
CTD
PMID:33512557
NCBI chr 3:69,683,328...69,734,550
Ensembl chr 3:69,683,313...69,734,516
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Ctss
cathepsin S
decreases expression
ISO
thifluzamide results in decreased expression of CTSS mRNA
CTD
PMID:33512557
NCBI chr 2:183,086,437...183,114,483
Ensembl chr 2:183,086,437...183,114,483
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Cxcr4
C-X-C motif chemokine receptor 4
decreases expression
ISO
thifluzamide results in decreased expression of CXCR4 mRNA
CTD
PMID:33512557
NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
G
Daam1
dishevelled associated activator of morphogenesis 1
decreases expression
ISO
thifluzamide results in decreased expression of DAAM1 mRNA
CTD
PMID:33512557
NCBI chr 6:90,389,544...90,550,114
Ensembl chr 6:90,389,688...90,550,114
G
Dcx
doublecortin
decreases expression
ISO
thifluzamide results in decreased expression of DCX mRNA
CTD
PMID:33512557
NCBI chr X:107,430,767...107,573,612
Ensembl chr X:107,430,767...107,507,476
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Ddc
dopa decarboxylase
decreases expression
ISO
thifluzamide results in decreased expression of DDC mRNA
CTD
PMID:33512557
NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208
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Ddit3
DNA-damage inducible transcript 3
increases expression
ISO
thifluzamide results in increased expression of DDIT3 mRNA
CTD
PMID:33512557
NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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Ddit4
DNA-damage-inducible transcript 4
increases expression
ISO
thifluzamide results in increased expression of DDIT4 mRNA
CTD
PMID:33512557
NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
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Depdc1b
DEP domain containing 1B
increases expression
ISO
thifluzamide results in increased expression of DEPDC1B mRNA
CTD
PMID:33512557
NCBI chr 2:39,891,163...39,963,779
Ensembl chr 2:39,891,481...39,963,779
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Dnm1
dynamin 1
decreases expression
ISO
thifluzamide results in decreased expression of DNM1 mRNA
CTD
PMID:33512557
NCBI chr 3:15,604,782...15,648,654
Ensembl chr 3:15,604,784...15,648,538
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Dpm2
dolichyl-phosphate mannosyltransferase subunit 2, regulatory
increases expression
ISO
thifluzamide results in increased expression of DPM2 mRNA
CTD
PMID:33512557
NCBI chr 3:15,855,952...15,858,867
Ensembl chr 3:15,856,182...15,869,165 Ensembl chr 3:15,856,182...15,869,165
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Drd2
dopamine receptor D2
decreases expression
ISO
thifluzamide results in decreased expression of DRD2 mRNA
CTD
PMID:33512557
NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
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Dusp14
dual specificity phosphatase 14
increases expression
ISO
thifluzamide results in increased expression of DUSP14 mRNA
CTD
PMID:33512557
NCBI chr10:68,936,483...68,966,347
Ensembl chr10:68,935,330...68,965,329
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Dusp22
dual specificity phosphatase 22
increases expression
ISO
thifluzamide results in increased expression of DUSP22 mRNA
CTD
PMID:33512557
NCBI chr17:33,780,980...33,831,241
Ensembl chr17:33,780,981...33,831,321
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Dusp4
dual specificity phosphatase 4
increases expression
ISO
thifluzamide results in increased expression of DUSP4 mRNA
CTD
PMID:33512557
NCBI chr16:57,376,659...57,398,161
Ensembl chr16:57,377,229...57,398,138
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Eea1
early endosome antigen 1
increases expression
ISO
thifluzamide results in increased expression of EEA1 mRNA
CTD
PMID:33512557
NCBI chr 7:30,554,686...30,722,186
Ensembl chr 7:30,554,552...30,718,487
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Egr1
early growth response 1
increases expression
ISO
thifluzamide results in increased expression of EGR1 mRNA
CTD
PMID:33512557
NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
G
Eif1
eukaryotic translation initiation factor 1
increases expression
ISO
thifluzamide results in increased expression of EIF1 mRNA
CTD
PMID:33512557
NCBI chr10:85,246,751...85,248,842
Ensembl chr10:85,246,764...85,427,327 Ensembl chr 5:85,246,764...85,427,327
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Eif2s2
eukaryotic translation initiation factor 2 subunit beta
increases expression
ISO
thifluzamide results in increased expression of EIF2S2 mRNA
CTD
PMID:33512557
NCBI chr 3:143,374,652...143,395,460
Ensembl chr 3:143,373,686...143,395,432
G
Eif4ebp1
eukaryotic translation initiation factor 4E binding protein 1
increases expression
ISO
thifluzamide results in increased expression of EIF4EBP1 mRNA
CTD
PMID:33512557
NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
G
Elmod1
ELMO domain containing 1
decreases expression
ISO
thifluzamide results in decreased expression of ELMOD1 mRNA
CTD
PMID:33512557
NCBI chr 8:54,298,363...54,355,348
Ensembl chr 8:54,298,363...54,355,140
G
Ephb2
Eph receptor B2
decreases expression
ISO
thifluzamide results in decreased expression of EPHB2 mRNA
CTD
PMID:33512557
NCBI chr 5:148,889,574...149,077,027
Ensembl chr 5:148,897,246...149,077,059
G
Eps15
epidermal growth factor receptor pathway substrate 15
increases expression
ISO
thifluzamide results in increased expression of EPS15 mRNA
CTD
PMID:33512557
NCBI chr 5:124,045,865...124,146,221
Ensembl chr 5:124,045,926...124,146,221
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Ero1a
endoplasmic reticulum oxidoreductase 1 alpha
increases expression
ISO
thifluzamide results in increased expression of ERO1A mRNA
CTD
PMID:33512557
NCBI chr15:18,495,037...18,530,440
Ensembl chr15:18,492,945...18,530,478
G
Etnk1
ethanolamine kinase 1
decreases expression
ISO
thifluzamide results in decreased expression of ETNK1 mRNA
CTD
PMID:33512557
NCBI chr 4:176,126,056...176,170,325
Ensembl chr 4:176,126,180...176,193,770
G
Ets1
ETS proto-oncogene 1, transcription factor
increases expression
ISO
thifluzamide results in increased expression of ETS1 mRNA
CTD
PMID:33512557
NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010
G
Etv1
ETS variant transcription factor 1
decreases expression
ISO
thifluzamide results in decreased expression of ETV1 mRNA
CTD
PMID:33512557
NCBI chr 6:55,590,149...55,681,784
Ensembl chr 6:55,590,234...55,681,775
G
Exosc4
exosome component 4
decreases expression
ISO
thifluzamide results in decreased expression of EXOSC4 mRNA
CTD
PMID:33512557
NCBI chr 7:108,047,831...108,050,573
Ensembl chr 7:108,047,831...108,050,573
G
Exosc8
exosome component 8
increases expression
ISO
thifluzamide results in increased expression of EXOSC8 mRNA
CTD
PMID:33512557
NCBI chr 2:138,930,405...138,937,009
Ensembl chr 2:138,930,405...138,936,928
G
Fam72a
family with sequence similarity 72, member A
increases expression
ISO
thifluzamide results in increased expression of FAM72A mRNA
CTD
PMID:33512557
NCBI chr13:42,967,701...42,979,083
Ensembl chr13:42,967,578...42,984,208
G
Fgf8
fibroblast growth factor 8
decreases expression
ISO
thifluzamide results in decreased expression of FGF8 mRNA
CTD
PMID:33512557
NCBI chr 1:244,584,477...244,590,578
Ensembl chr 1:244,584,652...244,590,359
G
Fibin
fin bud initiation factor homolog
increases expression
ISO
thifluzamide results in increased expression of FIBIN mRNA
CTD
PMID:33512557
NCBI chr 3:96,942,405...96,944,676
Ensembl chr 3:96,942,406...96,944,676
G
Flna
filamin A
increases expression
ISO
thifluzamide results in increased expression of FLNA mRNA
CTD
PMID:33512557
NCBI chr X:152,007,758...152,034,266
Ensembl chr X:152,007,758...152,031,052
G
Fth1
ferritin heavy chain 1
increases expression
ISO
thifluzamide results in increased expression of FTH1 mRNA
CTD
PMID:33512557
NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
G
Ftl1
ferritin light chain 1
increases expression
ISO
thifluzamide results in increased expression of FTL mRNA
CTD
PMID:33512557
NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725 Ensembl chr10:95,936,387...95,939,725 Ensembl chr 2:95,936,387...95,939,725
G
Gadd45a
growth arrest and DNA-damage-inducible, alpha
increases expression
ISO
thifluzamide results in increased expression of GADD45A mRNA
CTD
PMID:33512557
NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
G
Gadd45b
growth arrest and DNA-damage-inducible, beta
increases expression
ISO
thifluzamide results in increased expression of GADD45B mRNA
CTD
PMID:33512557
NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046
G
Galnt3
polypeptide N-acetylgalactosaminyltransferase 3
decreases expression
ISO
thifluzamide results in decreased expression of GALNT3 mRNA
CTD
PMID:33512557
NCBI chr 3:50,742,500...50,779,266
Ensembl chr 3:50,742,512...50,766,268
G
Gclm
glutamate cysteine ligase, modifier subunit
increases expression
ISO
thifluzamide results in increased expression of GCLM mRNA
CTD
PMID:33512557
NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
G
Gdf15
growth differentiation factor 15
increases expression
ISO
thifluzamide results in increased expression of GDF15 mRNA
CTD
PMID:33512557
NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055
G
Gldc
glycine decarboxylase
decreases expression
ISO
thifluzamide results in decreased expression of GLDC mRNA
CTD
PMID:33512557
NCBI chr 1:227,883,249...227,962,119
Ensembl chr 1:227,883,249...227,962,097
G
Glrx
glutaredoxin
decreases expression
ISO
thifluzamide results in decreased expression of GLRX mRNA
CTD
PMID:33512557
NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680
G
Gmip
Gem-interacting protein
decreases expression
ISO
thifluzamide results in decreased expression of GMIP mRNA
CTD
PMID:33512557
NCBI chr16:19,600,723...19,614,459
Ensembl chr16:19,600,723...19,614,027
G
Gnai2
G protein subunit alpha i2
decreases expression
ISO
thifluzamide results in decreased expression of GNAI2 mRNA
CTD
PMID:33512557
NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979
G
Gnb3
G protein subunit beta 3
decreases expression
ISO
thifluzamide results in decreased expression of GNB3 mRNA
CTD
PMID:33512557
NCBI chr 4:157,639,468...157,645,171
Ensembl chr 4:157,639,469...157,645,173
G
Got1
glutamic-oxaloacetic transaminase 1
increases expression
ISO
thifluzamide results in increased expression of GOT1 mRNA
CTD
PMID:33512557
NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
G
Grb10
growth factor receptor bound protein 10
increases expression
ISO
thifluzamide results in increased expression of GRB10 mRNA
CTD
PMID:33512557
NCBI chr14:86,495,051...86,602,800
Ensembl chr14:86,495,054...86,602,806
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Gria2
glutamate ionotropic receptor AMPA type subunit 2
decreases expression
ISO
thifluzamide results in decreased expression of GRIA2 mRNA
CTD
PMID:33512557
NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510
G
Grin2d
glutamate ionotropic receptor NMDA type subunit 2D
decreases expression
ISO
thifluzamide results in decreased expression of GRIN2D mRNA
CTD
PMID:33512557
NCBI chr 1:96,306,871...96,346,994
Ensembl chr 1:96,308,365...96,344,793
G
Grm4
glutamate metabotropic receptor 4
decreases expression
ISO
thifluzamide results in decreased expression of GRM4 mRNA
CTD
PMID:33512557
NCBI chr20:5,484,172...5,572,821
Ensembl chr20:5,481,124...5,572,821
G
Gsr
glutathione-disulfide reductase
increases expression
ISO
thifluzamide results in increased expression of GSR mRNA
CTD
PMID:33512557
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
G
Gstm2
glutathione S-transferase mu 2
decreases expression
ISO
thifluzamide results in decreased expression of GSTM2 mRNA
CTD
PMID:33512557
NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961
G
H1f0
H1.0 linker histone
increases expression
ISO
thifluzamide results in increased expression of H1-0 mRNA
CTD
PMID:33512557
NCBI chr 7:110,592,834...110,594,694
Ensembl chr 7:110,592,208...110,594,694
G
H1f2
H1.2 linker histone, cluster member
increases expression
ISO
thifluzamide results in increased expression of H1-2 mRNA
CTD
PMID:33512557
NCBI chr17:41,391,106...41,392,597
Ensembl chr17:41,388,477...41,392,635
G
H2bc3
H2B clustered histone 3
increases expression
ISO
thifluzamide results in increased expression of H2BC3 mRNA
CTD
PMID:33512557
NCBI chr17:41,380,056...41,380,686
G
Herpud1
homocysteine inducible ER protein with ubiquitin like domain 1
increases expression
ISO
thifluzamide results in increased expression of HERPUD1 mRNA
CTD
PMID:33512557
NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424
G
Hes5
hes family bHLH transcription factor 5
decreases expression
ISO
thifluzamide results in decreased expression of HES5 mRNA
CTD
PMID:33512557
NCBI chr 5:165,522,138...165,523,684
Ensembl chr 5:165,522,234...165,523,001
G
Hhip
Hedgehog-interacting protein
increases expression
ISO
thifluzamide results in increased expression of HHIP mRNA
CTD
PMID:33512557
NCBI chr19:27,863,684...27,952,528
Ensembl chr19:27,863,213...27,952,528
G
Hist1h2ah
histone cluster 1 H2A family member H
increases expression
ISO
thifluzamide results in increased expression of H2AC11 mRNA
CTD
PMID:33512557
NCBI chr17:41,384,521...41,385,018
G
Hist1h2al1
histone cluster 1 H2A family like 1
increases expression
ISO
thifluzamide results in increased expression of H2AC6 mRNA
CTD
PMID:33512557
NCBI chr17:42,707,954...42,708,420
G
Hist1h2bd
histone cluster 1 H2B family member D
increases expression
ISO
thifluzamide results in increased expression of H2BC5 mRNA
CTD
PMID:33512557
NCBI chr17:42,792,887...42,793,268
G
Hmox1
heme oxygenase 1
increases expression
ISO
thifluzamide results in increased expression of HMOX1 mRNA
CTD
PMID:33512557
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
G
Hnrnpm
heterogeneous nuclear ribonucleoprotein M
decreases expression
ISO
thifluzamide results in decreased expression of HNRNPM mRNA
CTD
PMID:33512557
NCBI chr 7:14,438,703...14,476,781
Ensembl chr 7:14,438,688...14,476,762
G
Hsd17b8
hydroxysteroid (17-beta) dehydrogenase 8
decreases expression
ISO
thifluzamide results in decreased expression of HSD17B8 mRNA
CTD
PMID:33512557
NCBI chr20:4,826,725...4,828,742
Ensembl chr20:4,822,026...4,828,742
G
Hspa8
heat shock protein family A (Hsp70) member 8
increases expression
ISO
thifluzamide results in increased expression of HSPA8 mRNA
CTD
PMID:33512557
NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
G
Hyou1
hypoxia up-regulated 1
increases expression
ISO
thifluzamide results in increased expression of HYOU1 mRNA
CTD
PMID:33512557
NCBI chr 8:44,706,073...44,718,189
Ensembl chr 8:44,706,263...44,718,186
G
Ide
insulin degrading enzyme
increases expression
ISO
thifluzamide results in increased expression of IDE mRNA
CTD
PMID:33512557
NCBI chr 1:235,002,984...235,102,448
Ensembl chr 1:234,995,351...235,102,440
G
Idh3a
isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha
increases expression
ISO
thifluzamide results in increased expression of IDH3A mRNA
CTD
PMID:33512557
NCBI chr 8:54,971,694...54,991,085
Ensembl chr 8:54,971,740...54,991,084
G
Ifi44
interferon-induced protein 44
decreases expression
ISO
thifluzamide results in decreased expression of IFI44 mRNA
CTD
PMID:33512557
NCBI chr 2:240,626,058...240,643,879
Ensembl chr 2:240,626,066...240,643,844
G
Ifitm2
interferon induced transmembrane protein 2
decreases expression
ISO
thifluzamide results in decreased expression of IFITM2 mRNA
CTD
PMID:33512557
NCBI chr 1:196,051,539...196,052,719
Ensembl chr 1:196,051,537...196,052,741
G
Ifitm3
interferon induced transmembrane protein 3
decreases expression
ISO
thifluzamide results in decreased expression of IFITM3 mRNA
CTD
PMID:33512557
NCBI chr 1:196,111,026...196,112,135
Ensembl chr 1:196,111,043...196,112,203
G
Ifrd1
interferon-related developmental regulator 1
increases expression
ISO
thifluzamide results in increased expression of IFRD1 mRNA
CTD
PMID:33512557
NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990
G
Ikzf1
IKAROS family zinc finger 1
decreases expression
ISO
thifluzamide results in decreased expression of IKZF1 mRNA
CTD
PMID:33512557
NCBI chr14:86,255,065...86,340,839
Ensembl chr14:86,255,065...86,342,416
G
Inhbe
inhibin subunit beta E
increases expression
ISO
thifluzamide results in increased expression of INHBE mRNA
CTD
PMID:33512557
NCBI chr 7:63,176,221...63,179,209
Ensembl chr 7:63,176,219...63,179,172
G
Ipo5
importin 5
increases expression
ISO
thifluzamide results in increased expression of IPO5 mRNA
CTD
PMID:33512557
NCBI chr15:97,990,755...98,041,074
Ensembl chr15:98,005,299...98,041,126
G
Irf1
interferon regulatory factor 1
increases expression
ISO
thifluzamide results in increased expression of IRF1 mRNA
CTD
PMID:33512557
NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
G
Isl1
ISL LIM homeobox 1
decreases expression
ISO
thifluzamide results in decreased expression of ISL1 mRNA
CTD
PMID:33512557
NCBI chr 2:48,079,412...48,090,704
Ensembl chr 2:48,080,522...48,095,584
G
Itpr1
inositol 1,4,5-trisphosphate receptor, type 1
increases expression
ISO
thifluzamide results in increased expression of ITPR1 mRNA
CTD
PMID:33512557
NCBI chr 4:141,187,377...141,554,240
Ensembl chr 4:141,187,418...141,510,491
G
Itpr2
inositol 1,4,5-trisphosphate receptor, type 2
decreases expression
ISO
thifluzamide results in decreased expression of ITPR2 mRNA
CTD
PMID:33512557
NCBI chr 4:179,028,594...179,434,657
Ensembl chr 4:179,027,281...179,404,164
G
Jmjd6
jumonji domain containing 6, arginine demethylase and lysine hydroxylase
increases expression
ISO
thifluzamide results in increased expression of JMJD6 mRNA
CTD
PMID:33512557
NCBI chr10:102,041,131...102,047,182
Ensembl chr10:102,041,120...102,047,182
G
Kars1
lysyl-tRNA synthetase 1
decreases expression
ISO
thifluzamide results in decreased expression of KARS1 mRNA
CTD
PMID:33512557
NCBI chr19:39,957,846...39,976,837
Ensembl chr19:39,957,846...39,977,632
G
Kcnq2
potassium voltage-gated channel subfamily Q member 2
decreases expression
ISO
thifluzamide results in decreased expression of KCNQ2 mRNA
CTD
PMID:33512557
NCBI chr 3:168,194,776...168,253,831
Ensembl chr 3:168,195,357...168,275,071
G
Kdelr2
KDEL endoplasmic reticulum protein retention receptor 2
increases expression
ISO
thifluzamide results in increased expression of KDELR2 mRNA
CTD
PMID:33512557
NCBI chr12:11,138,820...11,157,117
Ensembl chr12:11,138,820...11,157,153
G
Kif13a
kinesin family member 13A
decreases expression
ISO
thifluzamide results in decreased expression of KIF13A mRNA
CTD
PMID:33512557
NCBI chr17:17,766,597...17,948,517
Ensembl chr17:17,766,597...17,943,615
G
Kif20a
kinesin family member 20A
increases expression
ISO
thifluzamide results in increased expression of KIF20A mRNA
CTD
PMID:33512557
NCBI chr18:26,230,294...26,238,780
Ensembl chr18:26,230,230...26,238,780
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Klhl24
kelch-like family member 24
decreases expression
ISO
thifluzamide results in decreased expression of KLHL24 mRNA
CTD
PMID:33512557
NCBI chr11:80,843,621...80,877,649
Ensembl chr11:80,846,755...80,877,636
G
L1cam
L1 cell adhesion molecule
decreases expression
ISO
thifluzamide results in decreased expression of L1CAM mRNA
CTD
PMID:33512557
NCBI chr X:151,597,270...151,623,776
Ensembl chr X:151,597,277...151,623,857
G
Lamp3
lysosomal-associated membrane protein 3
increases expression
ISO
thifluzamide results in increased expression of LAMP3 mRNA
CTD
PMID:33512557
NCBI chr11:81,153,491...81,224,643
Ensembl chr11:81,193,649...81,221,784
G
Lmod1
leiomodin 1
decreases expression
ISO
thifluzamide results in decreased expression of LMOD1 mRNA
CTD
PMID:33512557
NCBI chr13:46,754,048...46,796,186
Ensembl chr13:46,754,033...46,794,900
G
Loxl1
lysyl oxidase-like 1
decreases expression
ISO
thifluzamide results in decreased expression of LOXL1 mRNA
CTD
PMID:33512557
NCBI chr 8:58,691,763...58,716,365
Ensembl chr 8:58,692,593...58,716,356
G
Lpcat1
lysophosphatidylcholine acyltransferase 1
decreases expression
ISO
thifluzamide results in decreased expression of LPCAT1 mRNA
CTD
PMID:33512557
NCBI chr 1:29,766,070...29,816,401
Ensembl chr 1:29,766,071...29,816,401
G
Map1lc3b
microtubule-associated protein 1 light chain 3 beta
increases expression
ISO
thifluzamide results in increased expression of MAP1LC3B mRNA
CTD
PMID:33512557
NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690 Ensembl chr16:49,665,791...49,677,690
G
Map2
microtubule-associated protein 2
decreases expression
ISO
thifluzamide results in decreased expression of MAP2 mRNA
CTD
PMID:33512557
NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809
G
Map6
microtubule-associated protein 6
decreases expression
ISO
thifluzamide results in decreased expression of MAP6 mRNA
CTD
PMID:33512557
NCBI chr 1:153,568,020...153,634,415
Ensembl chr 1:153,568,368...153,634,414
G
Mdk
midkine
increases expression
ISO
thifluzamide results in increased expression of MDK mRNA
CTD
PMID:33512557
NCBI chr 3:77,901,134...77,903,997
Ensembl chr 3:77,901,158...77,903,130
G
Me1
malic enzyme 1
increases expression
ISO
thifluzamide results in increased expression of ME1 mRNA
CTD
PMID:33512557
NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304
G
Metrn
meteorin, glial cell differentiation regulator
decreases expression
ISO
thifluzamide results in decreased expression of METRN mRNA
CTD
PMID:33512557
NCBI chr10:14,816,684...14,818,702
Ensembl chr10:14,816,572...14,818,701
G
Mok
MOK protein kinase
increases expression
ISO
thifluzamide results in increased expression of MOK mRNA
CTD
PMID:33512557
NCBI chr 6:129,823,794...129,854,669
Ensembl chr 6:129,823,795...129,854,700
G
Msi2
musashi RNA-binding protein 2
decreases expression
ISO
thifluzamide results in decreased expression of MSI2 mRNA
CTD
PMID:33512557
NCBI chr10:73,143,760...73,510,566
Ensembl chr10:73,147,380...73,510,157
G
Mt-nd6
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6
decreases expression
ISO
thifluzamide results in decreased expression of ND6 mRNA
CTD
PMID:33512557
NCBI chr MT:13,543...14,061 NCBI chr MT:13,543...14,061 NCBI chr MT:13,543...14,061 NCBI chr MT:13,543...14,061 NCBI chr MT:13,543...14,061 NCBI chr MT:13,543...14,061 NCBI chr MT:13,543...14,061 NCBI chr MT:13,543...14,061 NCBI chr MT:13,543...14,061 NCBI chr MT:13,543...14,061 NCBI chr MT:13,543...14,061 NCBI chr MT:13,543...14,061 NCBI chr MT:13,543...14,061
Ensembl chr MT:13,543...14,061
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Mt2A
metallothionein 2A
increases expression
ISO
thifluzamide results in increased expression of MT2A mRNA
CTD
PMID:33512557
NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
G
Mthfd2
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
increases expression
ISO
thifluzamide results in increased expression of MTHFD2 mRNA
CTD
PMID:33512557
NCBI chr 4:115,811,135...115,822,663
Ensembl chr 4:115,811,139...115,822,608
G
Myb
MYB proto-oncogene, transcription factor
decreases expression
ISO
thifluzamide results in decreased expression of MYB mRNA
CTD
PMID:33512557
NCBI chr 1:15,939,771...15,973,367
Ensembl chr 1:15,939,761...15,973,057
G
Myc
MYC proto-oncogene, bHLH transcription factor
increases expression
ISO
thifluzamide results in increased expression of MYC mRNA
CTD
PMID:33512557
NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
G
Myl4
myosin, light chain 4
decreases expression
ISO
thifluzamide results in decreased expression of MYL4 mRNA
CTD
PMID:33512557
NCBI chr10:89,449,456...89,485,365
Ensembl chr10:89,449,443...89,485,363
G
Nav1
neuron navigator 1
decreases expression
ISO
thifluzamide results in decreased expression of NAV1 mRNA
CTD
PMID:33512557
NCBI chr13:46,866,972...47,119,368
Ensembl chr13:46,873,689...47,126,449
G
Ncan
neurocan
decreases expression
ISO
thifluzamide results in decreased expression of NCAN mRNA
CTD
PMID:33512557
NCBI chr16:19,301,969...19,328,436
Ensembl chr16:19,301,969...19,328,436
G
Nefl
neurofilament light chain
decreases expression
ISO
thifluzamide results in decreased expression of NEFL mRNA
CTD
PMID:33512557
NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793
G
Nek2
NIMA-related kinase 2
increases expression
ISO
thifluzamide results in increased expression of NEK2 mRNA
CTD
PMID:33512557
NCBI chr13:103,405,818...103,419,063
Ensembl chr13:103,405,819...103,419,051
G
Nqo1
NAD(P)H quinone dehydrogenase 1
increases expression
ISO
thifluzamide results in increased expression of NQO1 mRNA
CTD
PMID:33512557
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
G
Nr2f1
nuclear receptor subfamily 2, group F, member 1
decreases expression
ISO
thifluzamide results in decreased expression of NR2F1 mRNA
CTD
PMID:33512557
NCBI chr 2:8,040,375...8,050,123
Ensembl chr 2:8,040,377...8,050,123
G
Nr3c1
nuclear receptor subfamily 3, group C, member 1
increases expression
ISO
thifluzamide results in increased expression of NR3C1 mRNA
CTD
PMID:33512557
NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
G
Nr4a2
nuclear receptor subfamily 4, group A, member 2
decreases expression
ISO
thifluzamide results in decreased expression of NR4A2 mRNA
CTD
PMID:33512557
NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877
G
Nrcam
neuronal cell adhesion molecule
decreases expression
ISO
thifluzamide results in decreased expression of NRCAM mRNA
CTD
PMID:33512557
NCBI chr 6:61,402,813...61,698,536
Ensembl chr 6:61,329,863...61,702,992
G
Nrxn1
neurexin 1
decreases expression
ISO
thifluzamide results in decreased expression of NRXN1 mRNA
CTD
PMID:33512557
NCBI chr 6:3,177,788...4,323,848
Ensembl chr 6:3,177,897...4,322,710
G
Olfml2b
olfactomedin-like 2B
decreases expression
ISO
thifluzamide results in decreased expression of OLFML2B mRNA
CTD
PMID:33512557
NCBI chr13:82,869,414...82,906,607
Ensembl chr13:82,869,433...82,906,607
G
Ormdl3
ORMDL sphingolipid biosynthesis regulator 3
decreases expression
ISO
thifluzamide results in decreased expression of ORMDL3 mRNA
CTD
PMID:33512557
NCBI chr10:83,590,052...83,596,035
Ensembl chr10:83,590,071...83,598,620
G
P4ha2
prolyl 4-hydroxylase subunit alpha 2
increases expression
ISO
thifluzamide results in increased expression of P4HA2 mRNA
CTD
PMID:33512557
NCBI chr10:38,243,136...38,271,983
Ensembl chr10:38,243,139...38,287,314
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Pcdh8
protocadherin 8
increases expression
ISO
thifluzamide results in increased expression of PCDH8 mRNA
CTD
PMID:33512557
NCBI chr15:55,198,470...55,203,039
Ensembl chr15:55,198,459...55,205,872
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Pdgfb
platelet derived growth factor subunit B
decreases expression
ISO
thifluzamide results in decreased expression of PDGFB mRNA
CTD
PMID:33512557
NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
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Pebp1
phosphatidylethanolamine binding protein 1
decreases expression
ISO
thifluzamide results in decreased expression of PEBP1 mRNA
CTD
PMID:33512557
NCBI chr12:39,302,864...39,307,064
Ensembl chr12:39,302,840...39,307,862
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Peg10
paternally expressed 10
decreases expression
ISO
thifluzamide results in decreased expression of PEG10 mRNA
CTD
PMID:33512557
NCBI chr 4:32,842,441...32,855,639
Ensembl chr 4:32,848,493...32,852,621
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Phgdh
phosphoglycerate dehydrogenase
increases expression
ISO
thifluzamide results in increased expression of PHGDH mRNA
CTD
PMID:33512557
NCBI chr 2:185,906,962...185,936,054
Ensembl chr 2:185,906,966...185,935,944
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Phlda1
pleckstrin homology-like domain, family A, member 1
decreases expression
ISO
thifluzamide results in decreased expression of PHLDA1 mRNA
CTD
PMID:33512557
NCBI chr 7:46,967,433...46,969,637
Ensembl chr 7:46,967,409...46,969,861
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Pink1
PTEN induced kinase 1
decreases expression
ISO
thifluzamide results in decreased expression of PINK1 mRNA
CTD
PMID:33512557
NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
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Plcb3
phospholipase C beta 3
decreases expression
ISO
thifluzamide results in decreased expression of PLCB3 mRNA
CTD
PMID:33512557
NCBI chr 1:204,143,257...204,160,384
Ensembl chr 1:204,144,956...204,160,228
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Pmaip1
phorbol-12-myristate-13-acetate-induced protein 1
increases expression
ISO
thifluzamide results in increased expression of PMAIP1 mRNA
CTD
PMID:33512557
NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429
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Pou4f2
POU class 4 homeobox 2
decreases expression
ISO
thifluzamide results in decreased expression of POU4F2 mRNA
CTD
PMID:33512557
NCBI chr19:29,486,686...29,490,327
Ensembl chr19:29,486,686...29,490,327
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Ppp1r17
protein phosphatase 1, regulatory subunit 17
decreases expression
ISO
thifluzamide results in decreased expression of PPP1R17 mRNA
CTD
PMID:33512557
NCBI chr 4:85,213,595...85,230,607
Ensembl chr 4:85,213,887...85,230,603
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Prr11
proline rich 11
increases expression
ISO
thifluzamide results in increased expression of PRR11 mRNA
CTD
PMID:33512557
NCBI chr10:71,898,858...71,943,325
Ensembl chr10:71,901,202...71,921,012
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Psat1
phosphoserine aminotransferase 1
increases expression
ISO
thifluzamide results in increased expression of PSAT1 mRNA
CTD
PMID:33512557
NCBI chr 1:213,196,709...213,218,564
Ensembl chr 1:213,196,709...213,218,682
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Ptprf
protein tyrosine phosphatase, receptor type, F
decreases expression
ISO
thifluzamide results in decreased expression of PTPRF mRNA
CTD
PMID:33512557
NCBI chr 5:131,741,959...131,824,000
Ensembl chr 5:131,742,754...131,810,023
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Rab31
RAB31, member RAS oncogene family
decreases expression
ISO
thifluzamide results in decreased expression of RAB31 mRNA
CTD
PMID:33512557
NCBI chr 9:105,246,712...105,382,973
Ensembl chr 9:105,246,709...105,381,253
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Rbx1
ring-box 1
decreases expression
ISO
thifluzamide results in decreased expression of RBX1 mRNA
CTD
PMID:33512557
NCBI chr 7:112,976,863...113,001,051
Ensembl chr 7:112,990,835...113,001,051
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Reln
reelin
decreases expression
ISO
thifluzamide results in decreased expression of RELN mRNA
CTD
PMID:33512557
NCBI chr 4:12,736,177...13,162,956
Ensembl chr 4:12,736,130...13,162,211
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Rpl28
ribosomal protein L28
increases expression
ISO
thifluzamide results in increased expression of RPL28 mRNA
CTD
PMID:33512557
NCBI chr 1:69,052,148...69,054,735
Ensembl chr 1:69,053,203...69,055,032
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Rpsa
ribosomal protein SA
increases expression
ISO
thifluzamide results in increased expression of RPSA mRNA
CTD
PMID:33512557
NCBI chr 8:119,851,225...119,855,103
Ensembl chr 8:119,851,225...119,855,247
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Rsl24d1
ribosomal L24 domain containing 1
increases expression
ISO
thifluzamide results in increased expression of RSL24D1 mRNA
CTD
PMID:33512557
NCBI chr 8:73,852,991...73,861,996
Ensembl chr 8:73,852,996...73,862,001
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Rxylt1
ribitol xylosyltransferase 1
increases expression
ISO
thifluzamide results in increased expression of RXYLT1 mRNA
CTD
PMID:33512557
NCBI chr 7:57,770,841...57,782,695
Ensembl chr 7:57,770,842...57,782,657
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Satb1
SATB homeobox 1
decreases expression
ISO
thifluzamide results in decreased expression of SATB1 mRNA
CTD
PMID:33512557
NCBI chr 9:4,677,817...4,773,061
Ensembl chr 9:4,680,920...4,753,251
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Sel1l
SEL1L adaptor subunit of SYVN1 ubiquitin ligase
increases expression
ISO
thifluzamide results in increased expression of SEL1L mRNA
CTD
PMID:33512557
NCBI chr 6:110,735,450...110,779,695
Ensembl chr 6:110,735,450...110,779,648
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Sema6a
semaphorin 6A
decreases expression
ISO
thifluzamide results in decreased expression of SEMA6A mRNA
CTD
PMID:33512557
NCBI chr18:40,050,623...40,171,954
Ensembl chr18:40,050,624...40,171,954
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Sephs2
selenophosphate synthetase 2
increases expression
ISO
thifluzamide results in increased expression of SEPHS2 mRNA
CTD
PMID:33512557
NCBI chr 1:181,893,146...181,895,464
Ensembl chr 1:181,892,599...181,895,497
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Serpine2
serpin family E member 2
increases expression
ISO
thifluzamide results in increased expression of SERPINE2 mRNA
CTD
PMID:33512557
NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826
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Sesn2
sestrin 2
increases expression
ISO
thifluzamide results in increased expression of SESN2 mRNA
CTD
PMID:33512557
NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260
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Sgcb
sarcoglycan, beta
decreases expression
ISO
thifluzamide results in decreased expression of SGCB mRNA
CTD
PMID:33512557
NCBI chr14:34,563,614...34,578,614
Ensembl chr14:34,563,608...34,578,583
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Slc17a6
solute carrier family 17 member 6
decreases expression
ISO
thifluzamide results in decreased expression of SLC17A6 mRNA
CTD
PMID:33512557
NCBI chr 1:101,212,489...101,252,543
Ensembl chr 1:101,212,489...101,252,542
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Slc1a2
solute carrier family 1 member 2
decreases expression
ISO
thifluzamide results in decreased expression of SLC1A2 mRNA
CTD
PMID:33512557
NCBI chr 3:89,005,129...89,135,469
Ensembl chr 3:89,005,129...89,126,498
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Slc1a4
solute carrier family 1 member 4
increases expression
ISO
thifluzamide results in increased expression of SLC1A4 mRNA
CTD
PMID:33512557
NCBI chr14:94,530,801...94,560,190
Ensembl chr14:94,529,084...94,560,418
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Slc2a6
solute carrier family 2 member 6
decreases expression
ISO
thifluzamide results in decreased expression of SLC2A6 mRNA
CTD
PMID:33512557
NCBI chr 3:10,348,395...10,355,208
Ensembl chr 3:10,348,395...10,355,208
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Slc38a1
solute carrier family 38, member 1
increases expression
ISO
thifluzamide results in increased expression of SLC38A1 mRNA
CTD
PMID:33512557
NCBI chr 7:127,733,230...127,802,541
Ensembl chr 7:127,738,226...127,802,218
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Slc3a2
solute carrier family 3 member 2
increases expression
ISO
thifluzamide results in increased expression of SLC3A2 mRNA
CTD
PMID:33512557
NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931
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Slc6a3
solute carrier family 6 member 3
decreases expression
ISO
thifluzamide results in decreased expression of SLC6A3 mRNA
CTD
PMID:33512557
NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
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Slc7a5
solute carrier family 7 member 5
increases expression
ISO
thifluzamide results in increased expression of SLC7A5 mRNA
CTD
PMID:33512557
NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823
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Slit2
slit guidance ligand 2
decreases expression
ISO
thifluzamide results in decreased expression of SLIT2 mRNA
CTD
PMID:33512557
NCBI chr14:62,616,337...62,955,934
Ensembl chr14:62,617,067...62,955,948
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Snai2
snail family transcriptional repressor 2
increases expression
ISO
thifluzamide results in increased expression of SNAI2 mRNA
CTD
PMID:33512557
NCBI chr11:86,182,788...86,186,203
Ensembl chr11:86,181,909...86,186,200
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Spag5
sperm associated antigen 5
increases expression
ISO
thifluzamide results in increased expression of SPAG5 mRNA
CTD
PMID:33512557
NCBI chr10:63,198,717...63,216,746
Ensembl chr10:63,198,768...63,216,745
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Spc25
SPC25 component of NDC80 kinetochore complex
increases expression
ISO
thifluzamide results in increased expression of SPC25 mRNA
CTD
PMID:33512557
NCBI chr 3:53,930,013...53,988,940
Ensembl chr 3:53,975,704...53,988,959
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Spdef
SAM pointed domain containing ets transcription factor
decreases expression
ISO
thifluzamide results in decreased expression of SPDEF mRNA
CTD
PMID:33512557
NCBI chr20:5,771,440...5,785,893
Ensembl chr20:5,771,441...5,785,893
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Spred2
sprouty-related, EVH1 domain containing 2
increases expression
ISO
thifluzamide results in increased expression of SPRED2 mRNA
CTD
PMID:33512557
NCBI chr14:94,149,210...94,250,787
Ensembl chr14:94,148,837...94,249,162
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Srsf10
serine and arginine rich splicing factor 10
increases expression
ISO
thifluzamide results in increased expression of SRSF10 mRNA
CTD
PMID:33512557
NCBI chr 5:148,088,759...148,102,964
Ensembl chr 5:148,088,823...148,101,768
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Sst
somatostatin
decreases expression
ISO
thifluzamide results in decreased expression of SST mRNA
CTD
PMID:33512557
NCBI chr11:76,956,896...76,958,173
Ensembl chr11:76,956,896...76,958,173
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Sytl1
synaptotagmin-like 1
increases expression
ISO
thifluzamide results in increased expression of SYTL1 mRNA
CTD
PMID:33512557
NCBI chr 5:145,452,524...145,462,940
Ensembl chr 5:145,422,669...145,462,940
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Taf9
TATA-box binding protein associated factor 9
increases expression
ISO
thifluzamide results in increased expression of TAF9 mRNA
CTD
PMID:33512557
NCBI chr 2:31,794,316...31,798,324
Ensembl chr 2:31,794,142...31,798,769
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Tcf4
transcription factor 4
decreases expression
ISO
thifluzamide results in decreased expression of TCF4 mRNA
CTD
PMID:33512557
NCBI chr18:62,941,739...63,288,126
Ensembl chr18:62,943,782...63,284,425
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Tfdp1
transcription factor Dp-1
decreases expression
ISO
thifluzamide results in decreased expression of TFDP1 mRNA
CTD
PMID:33512557
NCBI chr16:76,162,040...76,200,871
Ensembl chr16:76,162,043...76,200,817
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Tgfb3
transforming growth factor, beta 3
decreases expression
ISO
thifluzamide results in decreased expression of TGFB3 mRNA
CTD
PMID:33512557
NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564
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Tmem97
transmembrane protein 97
decreases expression
ISO
thifluzamide results in decreased expression of TMEM97 mRNA
CTD
PMID:33512557
NCBI chr10:63,438,228...63,447,311
Ensembl chr10:63,438,222...63,589,730
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Tnc
tenascin C
decreases expression
ISO
thifluzamide results in decreased expression of TNC mRNA
CTD
PMID:33512557
NCBI chr 5:77,375,851...77,460,712
Ensembl chr 5:77,375,851...77,460,624
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Top2a
DNA topoisomerase II alpha
increases expression
ISO
thifluzamide results in increased expression of TOP2A mRNA
CTD
PMID:33512557
NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874
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Tpi1
triosephosphate isomerase 1
decreases expression
ISO
thifluzamide results in decreased expression of TPI1 mRNA
CTD
PMID:33512557
NCBI chr 4:157,615,283...157,618,813
Ensembl chr 4:157,615,386...157,619,541
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Tpx2
TPX2, microtubule nucleation factor
increases expression
ISO
thifluzamide results in increased expression of TPX2 mRNA
CTD
PMID:33512557
NCBI chr 3:141,318,428...141,360,684
Ensembl chr 3:141,318,455...141,360,468
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Trib3
tribbles pseudokinase 3
increases expression
ISO
thifluzamide results in increased expression of TRIB3 mRNA
CTD
PMID:33512557
NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497
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Trim13
tripartite motif-containing 13
decreases expression
ISO
thifluzamide results in decreased expression of TRIM13 mRNA
CTD
PMID:33512557
NCBI chr15:35,733,548...35,772,676
Ensembl chr15:35,734,107...35,772,677
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Tsc22d3
TSC22 domain family, member 3
increases expression
ISO
thifluzamide results in increased expression of TSC22D3 mRNA
CTD
PMID:33512557
NCBI chr X:104,217,898...104,277,886
Ensembl chr X:104,217,925...104,276,861
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Ttk
Ttk protein kinase
increases expression
ISO
thifluzamide results in increased expression of TTK mRNA
CTD
PMID:33512557
NCBI chr 8:84,754,329...84,792,653
Ensembl chr 8:84,754,315...84,792,651
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Tubb2a
tubulin, beta 2A class IIa
decreases expression
ISO
thifluzamide results in decreased expression of TUBB2A mRNA
CTD
PMID:33512557
NCBI chr17:30,796,842...30,800,713
Ensembl chr17:30,747,503...30,800,714
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Tubb2b
tubulin, beta 2B class IIb
decreases expression
ISO
thifluzamide results in decreased expression of TUBB2B mRNA
CTD
PMID:33512557
NCBI chr17:30,747,734...30,750,781
Ensembl chr17:30,747,734...30,750,638
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Tubb3
tubulin, beta 3 class III
decreases expression
ISO
thifluzamide results in decreased expression of TUBB3 mRNA
CTD
PMID:33512557
NCBI chr19:51,457,187...51,466,243
Ensembl chr19:51,457,184...51,466,243
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Tut7
terminal uridylyl transferase 7
decreases expression
ISO
thifluzamide results in decreased expression of TUT7 mRNA
CTD
PMID:33512557
NCBI chr17:4,849,287...4,903,542
Ensembl chr17:4,849,283...4,903,169
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Txndc5
thioredoxin domain containing 5
increases expression
ISO
thifluzamide results in increased expression of TXNDC5 mRNA
CTD
PMID:33512557
NCBI chr17:26,289,880...26,318,025
Ensembl chr17:26,289,880...26,318,025
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Txnip
thioredoxin interacting protein
decreases expression
ISO
thifluzamide results in decreased expression of TXNIP mRNA
CTD
PMID:33512557
NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
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Txnrd1
thioredoxin reductase 1
increases expression
ISO
thifluzamide results in increased expression of TXNRD1 mRNA
CTD
PMID:33512557
NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
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Txnrd2
thioredoxin reductase 2
increases expression
ISO
thifluzamide results in increased expression of TXNRD2 mRNA
CTD
PMID:33512557
NCBI chr11:82,519,996...82,568,156
Ensembl chr11:82,519,999...82,568,156
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Ubb
ubiquitin B
increases expression
ISO
thifluzamide results in increased expression of UBB mRNA
CTD
PMID:33512557
NCBI chr10:47,247,630...47,249,335
Ensembl chr10:47,245,637...47,249,333
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Ube2c
ubiquitin-conjugating enzyme E2C
increases expression
ISO
thifluzamide results in increased expression of UBE2C mRNA
CTD
PMID:33512557
NCBI chr 3:153,506,636...153,509,036
Ensembl chr 3:153,506,636...153,513,339
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Uhrf1
ubiquitin-like with PHD and ring finger domains 1
decreases expression
ISO
thifluzamide results in decreased expression of UHRF1 mRNA
CTD
PMID:33512557
NCBI chr 9:1,133,117...1,154,639
Ensembl chr 9:1,134,909...1,154,631
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Vegfa
vascular endothelial growth factor A
increases expression
ISO
thifluzamide results in increased expression of VEGFA mRNA
CTD
PMID:33512557
NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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Vegfd
vascular endothelial growth factor D
decreases expression
ISO
thifluzamide results in decreased expression of VEGFD mRNA
CTD
PMID:33512557
NCBI chr X:30,073,122...30,108,413
Ensembl chr X:30,074,163...30,108,295
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Vim
vimentin
increases expression
ISO
thifluzamide results in increased expression of VIM mRNA
CTD
PMID:33512557
NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
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Wars1
tryptophanyl-tRNA synthetase 1
increases expression
ISO
thifluzamide results in increased expression of WARS1 mRNA
CTD
PMID:33512557
NCBI chr 6:127,776,088...127,807,273
Ensembl chr 6:127,776,090...127,807,269
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Wdtc1
WD and tetratricopeptide repeats 1
decreases expression
ISO
thifluzamide results in decreased expression of WDTC1 mRNA
CTD
PMID:33512557
NCBI chr 5:145,491,460...145,559,631
Ensembl chr 5:145,491,466...145,540,408
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Xbp1
X-box binding protein 1
increases expression
ISO
thifluzamide results in increased expression of XBP1 mRNA
CTD
PMID:33512557
NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
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Zeb2
zinc finger E-box binding homeobox 2
decreases expression
ISO
thifluzamide results in decreased expression of ZEB2 mRNA
CTD
PMID:33512557
NCBI chr 3:29,214,581...29,344,890
Ensembl chr 3:29,218,301...29,345,157
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Iyd
iodotyrosine deiodinase
multiple interactions
ISO
tribromsalan inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine]
CTD
PMID:33352258
NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319
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