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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:(R)-fluoxetine hydrochloride
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Accession:CHEBI:86996 term browser browse the term
Definition:A hydrochloride obtained by reaction of (R)-fluoxetine with one equivalent of hydrochloric acid.
Synonyms:exact_synonym: (3R)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine hydrochloride
 related_synonym: (-)-fluoxetine hydrochloride;   (3R)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-aminium chloride;   (R)-fluoxetine HCl;   Formula=C17H19ClF3NO;   InChI=1S/C17H18F3NO.ClH/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20;/h2-10,16,21H,11-12H2,1H3;1H/t16-;/m1./s1;   InChIKey=GIYXAJPCNFJEHY-PKLMIRHRSA-N;   SMILES=Cl.CNCC[C@@H](Oc1ccc(cc1)C(F)(F)F)c1ccccc1
 xref: CAS:114247-09-5
 cyclic_relationship: is_enantiomer_of CHEBI:86997


show annotations for term's descendants           Sort by:
fluoxetine hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc6a4 solute carrier family 6 member 4 decreases expression EXP fluoxetine decreases expression of Slc6a4 mRNA in the dorsal raphe nucleus RGD PMID:15936043 RGD:38549581 NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19867
    role 19837
      biological role 19835
        pharmacological role 19069
          neurotransmitter agent 16800
            serotonergic drug 4339
              serotonin uptake inhibitor 3462
                (R)-fluoxetine hydrochloride 1
                  fluoxetine hydrochloride 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19867
    subatomic particle 19865
      composite particle 19865
        hadron 19865
          baryon 19865
            nucleon 19865
              atomic nucleus 19865
                atom 19865
                  main group element atom 19803
                    p-block element atom 19803
                      halogen 18677
                        chlorine atom 18460
                          chlorine molecular entity 18460
                            elemental chlorine 8778
                              monoatomic chlorine 8763
                                chloride 8763
                                  chloride salt 8763
                                    organic chloride salt 1106
                                      hydrochloride 738
                                        (R)-fluoxetine hydrochloride 1
                                          fluoxetine hydrochloride 1
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