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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Pyridostigmine bromide
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Accession:CHEBI:8666 term browser browse the term
Synonyms:related_synonym: Formula=C9H13BrN2O2;   Formula=C9H13N2O2.Br;   InChI=1S/C9H13N2O2.BrH/c1-10(2)9(12)13-8-5-4-6-11(3)7-8;/h4-7H,1-3H3;1H/q+1;/p-1;   InChIKey=VNYBTNPBYXSMOO-UHFFFAOYSA-M;   Mestinon (TN);   SMILES=C=1(OC(N(C)C)=O)C=[N+](C=CC1)C.[Br-]
 xref: CAS:101-26-8;   KEGG:D00487
 xref_mesh: MESH:D011729


show annotations for term's descendants           Sort by:
Pyridostigmine bromide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity
multiple interactions
decreases expression		 ISO
EXP		 Pyridostigmine Bromide results in decreased activity of ACHE protein
[Pyridostigmine Bromide co-treated with DEET] results in decreased activity of ACHE protein; [Pyridostigmine Bromide co-treated with DEET] results in increased activity of ACHE protein; [Pyridostigmine Bromide co-treated with Permethrin co-treated with DEET] results in decreased activity of ACHE protein; [Pyridostigmine Bromide co-treated with Permethrin co-treated with DEET] results in increased activity of ACHE protein; [Pyridostigmine Bromide co-treated with Permethrin] results in decreased activity of ACHE protein; [Pyridostigmine Bromide co-treated with Permethrin] results in increased activity of ACHE protein; asoxime chloride affects the reaction [Pyridostigmine Bromide results in decreased activity of ACHE protein]; asoxime chloride promotes the reaction [Pyridostigmine Bromide inhibits the reaction [Soman results in decreased activity of ACHE protein]]; Pyridostigmine Bromide inhibits the reaction [Soman results in decreased activity of ACHE protein]
Pyridostigmine Bromide inhibits the reaction [Soman results in decreased activity of ACHE protein]; SOD2 protein SNP promotes the reaction [Pyridostigmine Bromide results in decreased expression of ACHE protein]		 CTD PMID:11248143 PMID:14751452 PMID:21354413 PMID:21414391 PMID:30176331 More... NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Ager advanced glycosylation end product-specific receptor multiple interactions ISO [Pyridostigmine Bromide co-treated with Permethrin] results in increased expression of AGER protein CTD PMID:32832901 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Aif1 allograft inflammatory factor 1 multiple interactions ISO [Pyridostigmine Bromide co-treated with Permethrin] results in increased expression of AIF1 protein CTD PMID:27984134 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668 		JBrowse link
G Alb albumin affects binding ISO Pyridostigmine Bromide binds to ALB protein CTD PMID:12029383 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Als2 alsin Rho guanine nucleotide exchange factor ALS2 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of ALS2 mRNA CTD PMID:28659758 NCBI chr 9:60,613,182...60,686,394
Ensembl chr 9:60,613,167...60,670,737 		JBrowse link
G Apc APC regulator of WNT signaling pathway multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of APC mRNA CTD PMID:28659758 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696 		JBrowse link
G Apoe apolipoprotein E multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of APOE mRNA CTD PMID:28659758 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of ATP5F1A mRNA CTD PMID:28659758 NCBI chr18:71,292,406...71,300,342
Ensembl chr18:71,292,374...71,300,794 		JBrowse link
G Atp5f1b ATP synthase F1 subunit beta multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of ATP5F1B mRNA CTD PMID:28659758 NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273 		JBrowse link
G Atp6ap1 ATPase H+ transporting accessory protein 1 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of ATP6AP1 mRNA CTD PMID:28659758 NCBI chr  X:152,079,954...152,087,034
Ensembl chr  X:152,079,865...152,087,034 		JBrowse link
G Atp6v0a2 ATPase H+ transporting V0 subunit a2 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of ATP6V0A2 mRNA CTD PMID:28659758 NCBI chr12:31,947,220...31,979,875
Ensembl chr12:31,822,733...32,007,069 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
decreases expression		 EXP
ISO		 [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of BAX protein
SOD2 protein SNP affects the reaction [Pyridostigmine Bromide results in decreased expression of BAX mRNA]; SOD2 protein SNP promotes the reaction [Pyridostigmine Bromide results in decreased expression of BAX protein]
Pyridostigmine Bromide results in decreased expression of BAX mRNA; Pyridostigmine Bromide results in decreased expression of BAX protein		 CTD PMID:12587291 PMID:31175926 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bche butyrylcholinesterase multiple interactions
decreases activity		 EXP [Pyridostigmine Bromide co-treated with DEET] results in increased activity of BCHE protein; [Pyridostigmine Bromide co-treated with Permethrin] results in increased activity of BCHE protein
Pyridostigmine Bromide results in decreased activity of BCHE protein		 CTD PMID:14751452 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression		 ISO SOD2 protein SNP inhibits the reaction [Pyridostigmine Bromide results in decreased expression of BCL2 mRNA]
Pyridostigmine Bromide results in decreased expression of BCL2 mRNA; Pyridostigmine Bromide results in decreased expression of BCL2 protein		 CTD PMID:31175926 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl6 BCL6, transcription repressor multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of BCL6 mRNA CTD PMID:28659758 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389 		JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions ISO [Pyridostigmine Bromide co-treated with Permethrin] results in decreased expression of BDNF protein; NLRP3 protein affects the reaction [[Pyridostigmine Bromide co-treated with Permethrin] results in decreased expression of BDNF protein] CTD PMID:32832901 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Casp3 caspase 3 decreases expression
multiple interactions		 ISO Pyridostigmine Bromide results in decreased expression of CASP3 mRNA; Pyridostigmine Bromide results in decreased expression of CASP3 protein
SOD2 protein SNP affects the reaction [Pyridostigmine Bromide results in decreased expression of CASP3 mRNA]; SOD2 protein SNP affects the reaction [Pyridostigmine Bromide results in decreased expression of CASP3 protein]		 CTD PMID:31175926 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp8 caspase 8 multiple interactions
affects expression
decreases expression		 ISO SOD2 protein SNP affects the reaction [Pyridostigmine Bromide affects the expression of CASP8 mRNA]
Pyridostigmine Bromide results in decreased expression of CASP8 protein		 CTD PMID:31175926 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Cat catalase multiple interactions
decreases expression
increases activity		 EXP
ISO		 [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of CAT mRNA
SOD2 protein SNP inhibits the reaction [Pyridostigmine Bromide results in decreased expression of CAT mRNA]
Pyridostigmine Bromide results in increased activity of CAT protein		 CTD PMID:28659758 PMID:31175926 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of CCL2 mRNA; Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of CCL2 mRNA] CTD PMID:29751049 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of and results in increased secretion of CCL3 protein CTD PMID:28659758 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccs copper chaperone for superoxide dismutase multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of CCS mRNA CTD PMID:28659758 NCBI chr 1:202,113,792...202,134,931
Ensembl chr 1:202,113,804...202,134,915 		JBrowse link
G Cd68 Cd68 molecule multiple interactions ISO [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of CD68 mRNA; Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of CD68 mRNA] CTD PMID:29751049 NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697 		JBrowse link
G Chat choline O-acetyltransferase multiple interactions EXP [Pyridostigmine Bromide co-treated with Permethrin co-treated with DEET] results in increased activity of CHAT protein CTD PMID:11248143 NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093 		JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 multiple interactions EXP [Pyridostigmine Bromide co-treated with Permethrin co-treated with DEET] promotes the reaction [AFDX 384 binds to CHRM2 protein]; [Pyridostigmine Bromide co-treated with Permethrin] promotes the reaction [AFDX 384 binds to CHRM2 protein]; Pyridostigmine Bromide promotes the reaction [AFDX 384 binds to CHRM2 protein] CTD PMID:11248143 PMID:14751452 NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103 		JBrowse link
G Cldn2 claudin 2 multiple interactions ISO [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of CLDN2 protein CTD PMID:29751049 NCBI chr  X:103,459,870...103,473,794
Ensembl chr  X:103,459,780...103,474,838 		JBrowse link
G Cldn5 claudin 5 multiple interactions ISO [Pyridostigmine Bromide co-treated with Permethrin] results in decreased expression of CLDN5 mRNA; [Pyridostigmine Bromide co-treated with Permethrin] results in decreased expression of CLDN5 protein CTD PMID:32832901 NCBI chr11:82,212,822...82,214,248
Ensembl chr11:82,211,475...82,214,992 		JBrowse link
G Cort cortistatin multiple interactions ISO [CORT protein co-treated with Pyridostigmine Bromide co-treated with DEET co-treated with Isoflurophate] affects the secretion of IL10 protein; [CORT protein co-treated with Pyridostigmine Bromide co-treated with DEET] affects the secretion of IL10 protein; [Pyridostigmine Bromide co-treated with DEET] affects the reaction [[CORT protein co-treated with Isoflurophate] affects the secretion of IL5 protein]; [Pyridostigmine Bromide co-treated with DEET] inhibits the reaction [[CORT protein co-treated with Isoflurophate] results in increased expression of LIF mRNA]; [Pyridostigmine Bromide co-treated with DEET] promotes the reaction [CORT protein inhibits the reaction [Isoflurophate results in increased expression of IL1B mRNA]]; [Pyridostigmine Bromide co-treated with DEET] promotes the reaction [CORT protein inhibits the reaction [Isoflurophate results in increased expression of IL6 mRNA]]; [Pyridostigmine Bromide co-treated with DEET] promotes the reaction [CORT protein inhibits the reaction [Isoflurophate results in increased expression of OSM mRNA]] CTD PMID:30339781 NCBI chr 5:159,560,591...159,562,032 JBrowse link
G Cox5b cytochrome c oxidase subunit 5B multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of COX5B mRNA CTD PMID:28659758 NCBI chr 9:38,921,980...38,923,806
Ensembl chr 9:38,921,967...38,925,052 		JBrowse link
G Cox6a1 cytochrome c oxidase subunit 6A1 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of COX6A1 mRNA CTD PMID:28659758 NCBI chr12:41,261,983...41,265,037
Ensembl chr12:41,261,967...41,265,041 		JBrowse link
G Cox7a2l cytochrome c oxidase subunit 7A2 like multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of COX7A2L mRNA CTD PMID:28659758 NCBI chr 6:11,184,064...11,198,287
Ensembl chr 6:11,184,285...11,198,273 		JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of CSF2 mRNA CTD PMID:28659758 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199 		JBrowse link
G Ctsb cathepsin B multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of CTSB mRNA CTD PMID:28659758 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of and results in increased secretion of CXCL10 protein CTD PMID:28659758 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions ISO [Pyridostigmine Bromide co-treated with DEET] inhibits the reaction [Isoflurophate results in increased secretion of CXCL1 protein] CTD PMID:30339781 NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511 		JBrowse link
G Cyc1 cytochrome c-1 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of CYC1 mRNA CTD PMID:28659758 NCBI chr 7:108,067,106...108,069,483
Ensembl chr 7:108,067,115...108,069,479 		JBrowse link
G Cygb cytoglobin multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of CYGB mRNA CTD PMID:28659758 NCBI chr10:101,877,675...101,887,442
Ensembl chr10:101,877,676...101,887,442 		JBrowse link
G Dhcr24 24-dehydrocholesterol reductase multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of DHCR24 mRNA CTD PMID:28659758 NCBI chr 5:121,344,552...121,371,124
Ensembl chr 5:121,344,575...121,371,137 		JBrowse link
G Dnm2 dynamin 2 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of DNM2 mRNA CTD PMID:28659758 NCBI chr 8:19,978,313...20,060,162
Ensembl chr 8:19,978,400...20,060,157 		JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions
decreases expression		 ISO SOD2 protein SNP inhibits the reaction [Pyridostigmine Bromide results in decreased expression of DNMT1 mRNA] CTD PMID:31175926 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659 		JBrowse link
G Duox2 dual oxidase 2 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of DUOX2 mRNA CTD PMID:28659758 NCBI chr 3:109,223,809...109,247,023
Ensembl chr 3:109,226,924...109,245,902 		JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of ERCC6 mRNA CTD PMID:28659758 NCBI chr16:7,764,983...7,835,587
Ensembl chr16:7,765,013...7,835,587 		JBrowse link
G Fgf2 fibroblast growth factor 2 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of and results in increased secretion of FGF2 protein CTD PMID:28659758 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of FMO2 mRNA CTD PMID:28659758 NCBI chr13:75,221,149...75,244,377
Ensembl chr13:75,224,402...75,244,308 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of GCLC mRNA CTD PMID:28659758 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions ISO [Pyridostigmine Bromide co-treated with Permethrin] results in increased expression of GFAP protein CTD PMID:27984134 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589 		JBrowse link
G Glyr1 glyoxylate reductase 1 homolog multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of GLYR1 mRNA CTD PMID:28659758 NCBI chr10:10,532,036...10,567,639
Ensembl chr10:10,532,154...10,567,637 		JBrowse link
G Gpx1 glutathione peroxidase 1 decreases expression
multiple interactions		 ISO Pyridostigmine Bromide results in decreased expression of GPX1 mRNA
SOD2 protein SNP inhibits the reaction [Pyridostigmine Bromide results in decreased expression of GPX1 mRNA]		 CTD PMID:31175926 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Gpx3 glutathione peroxidase 3 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of GPX3 mRNA CTD PMID:28659758 NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035 		JBrowse link
G Gpx4 glutathione peroxidase 4 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of GPX4 mRNA CTD PMID:28659758 NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982 		JBrowse link
G Gpx6 glutathione peroxidase 6 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of GPX6 mRNA CTD PMID:28659758 NCBI chr17:43,408,472...43,416,091
Ensembl chr17:43,408,472...43,416,091 		JBrowse link
G Gpx7 glutathione peroxidase 7 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of GPX7 mRNA CTD PMID:28659758 NCBI chr 5:123,145,151...123,153,141
Ensembl chr 5:123,144,331...123,153,004 		JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of GSR mRNA CTD PMID:28659758 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Gstk1 glutathione S-transferase kappa 1 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of GSTK1 mRNA CTD PMID:28659758 NCBI chr 4:71,118,979...71,123,298
Ensembl chr 4:71,118,896...71,123,292 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of GSTP1 mRNA CTD PMID:28659758 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions ISO [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased secretion of HMGB1 protein; [Pyridostigmine Bromide co-treated with Permethrin] results in increased expression of HMGB1 protein; Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased secretion of HMGB1 protein] CTD PMID:29751049 PMID:32832901 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of HMOX1 mRNA CTD PMID:28659758 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Ice2 interactor of little elongation complex ELL subunit 2 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of ICE2 mRNA CTD PMID:28659758 NCBI chr 8:70,043,419...70,085,217
Ensembl chr 8:70,043,424...70,084,995 		JBrowse link
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of IDH1 mRNA CTD PMID:28659758 NCBI chr 9:66,534,146...66,563,703
Ensembl chr 9:66,534,146...66,563,708 		JBrowse link
G Ift172 intraflagellar transport 172 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of IFT172 mRNA CTD PMID:28659758 NCBI chr 6:25,081,933...25,121,271
Ensembl chr 6:25,081,980...25,120,860 		JBrowse link
G Il10 interleukin 10 multiple interactions EXP
ISO		 [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in decreased expression of IL10 mRNA
[CORT protein co-treated with Pyridostigmine Bromide co-treated with DEET co-treated with Isoflurophate] affects the secretion of IL10 protein; [CORT protein co-treated with Pyridostigmine Bromide co-treated with DEET] affects the secretion of IL10 protein; [Pyridostigmine Bromide co-treated with DEET co-treated with Isoflurophate] affects the secretion of IL10 protein; [Pyridostigmine Bromide co-treated with DEET] affects the secretion of IL10 protein; [Pyridostigmine Bromide co-treated with DEET] inhibits the reaction [Isoflurophate results in increased expression of IL10 mRNA]		 CTD PMID:28659758 PMID:30339781 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il15 interleukin 15 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of and results in increased secretion of IL15 protein CTD PMID:28659758 NCBI chr19:25,640,025...25,706,818
Ensembl chr19:25,640,251...25,706,820 		JBrowse link
G Il18 interleukin 18 multiple interactions ISO [Pyridostigmine Bromide co-treated with Permethrin] results in increased expression of IL18 protein; NLRP3 protein affects the reaction [[Pyridostigmine Bromide co-treated with Permethrin] results in increased expression of IL18 protein] CTD PMID:32832901 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il1a interleukin 1 alpha multiple interactions EXP
ISO		 [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of and results in increased secretion of IL1A protein; [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of IL1A mRNA
[Pyridostigmine Bromide co-treated with DEET] results in increased secretion of IL1A protein		 CTD PMID:28659758 PMID:30339781 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP
ISO		 [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of and results in increased secretion of IL1B protein
[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of and results in increased secretion of IL1B protein; [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of IL1B mRNA; [Pyridostigmine Bromide co-treated with DEET] inhibits the reaction [Isoflurophate results in increased expression of IL1B mRNA]; [Pyridostigmine Bromide co-treated with DEET] promotes the reaction [CORT protein inhibits the reaction [Isoflurophate results in increased expression of IL1B mRNA]]; [Pyridostigmine Bromide co-treated with Permethrin] results in increased expression of IL1B protein; Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of and results in increased secretion of IL1B protein]; Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of IL1B mRNA]; NLRP3 protein affects the reaction [[Pyridostigmine Bromide co-treated with Permethrin] results in increased expression of IL1B protein]		 CTD PMID:28659758 PMID:29751049 PMID:30339781 PMID:32832901 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il2 interleukin 2 multiple interactions ISO [Pyridostigmine Bromide co-treated with DEET] results in increased secretion of IL2 protein CTD PMID:30339781 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il4 interleukin 4 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in decreased expression of IL4 mRNA CTD PMID:28659758 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il5 interleukin 5 multiple interactions EXP
ISO		 [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of and results in increased secretion of IL5 protein
[Pyridostigmine Bromide co-treated with DEET] affects the reaction [[CORT protein co-treated with Isoflurophate] affects the secretion of IL5 protein]		 CTD PMID:28659758 PMID:30339781 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213 		JBrowse link
G Il6 interleukin 6 multiple interactions EXP
ISO		 [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of and results in increased secretion of IL6 protein; [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of IL6 mRNA
[Pyridostigmine Bromide co-treated with Corticosterone] results in decreased expression of IL6 mRNA; [Pyridostigmine Bromide co-treated with DEET] inhibits the reaction [Isoflurophate results in increased expression of IL6 mRNA]; [Pyridostigmine Bromide co-treated with DEET] inhibits the reaction [Isoflurophate results in increased secretion of IL6 protein]; [Pyridostigmine Bromide co-treated with DEET] promotes the reaction [CORT protein inhibits the reaction [Isoflurophate results in increased expression of IL6 mRNA]]; [Pyridostigmine Bromide co-treated with DEET] results in increased secretion of IL6 protein; [Pyridostigmine Bromide co-treated with Permethrin] results in increased expression of IL6 protein; NLRP3 protein affects the reaction [[Pyridostigmine Bromide co-treated with Permethrin] results in increased expression of IL6 protein]		 CTD PMID:28500787 PMID:28659758 PMID:30339781 PMID:32832901 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Lep leptin multiple interactions ISO [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased secretion of LEP protein; Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased secretion of LEP protein] CTD PMID:29751049 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Lhpp phospholysine phosphohistidine inorganic pyrophosphate phosphatase multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of LHPP mRNA CTD PMID:28659758 NCBI chr 1:187,403,390...187,494,577
Ensembl chr 1:187,403,433...187,494,578 		JBrowse link
G Lif LIF, interleukin 6 family cytokine multiple interactions
decreases expression		 ISO [Pyridostigmine Bromide co-treated with DEET] inhibits the reaction [[CORT protein co-treated with Isoflurophate] results in increased expression of LIF mRNA]; [Pyridostigmine Bromide co-treated with DEET] inhibits the reaction [Isoflurophate results in increased expression of LIF mRNA]
Pyridostigmine Bromide results in decreased expression of LIF mRNA		 CTD PMID:28500787 PMID:30339781 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of MAPK1 mRNA CTD PMID:28659758 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of MAPK3 mRNA CTD PMID:28659758 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO [Chlorpyrifos co-treated with DEET co-treated with Pyridostigmine Bromide] results in increased phosphorylation of MAPK8 protein CTD PMID:34528356 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mpo myeloperoxidase multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of MPO mRNA CTD PMID:28659758 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Ndufa11 NADH:ubiquinone oxidoreductase subunit A11 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of NDUFA11 mRNA CTD PMID:28659758 NCBI chr 9:1,550,487...1,554,546
Ensembl chr 9:1,550,468...1,555,601 		JBrowse link
G Ndufa8 NADH:ubiquinone oxidoreductase subunit A8 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of NDUFA8 mRNA CTD PMID:28659758 NCBI chr 3:19,386,062...19,402,090
Ensembl chr 3:19,386,065...19,402,071 		JBrowse link
G Ndufa9 NADH:ubiquinone oxidoreductase subunit A9 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of NDUFA9 mRNA CTD PMID:28659758 NCBI chr 4:159,659,242...159,688,034
Ensembl chr 4:159,659,242...159,688,018 		JBrowse link
G Ndufb3 NADH:ubiquinone oxidoreductase subunit B3 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of NDUFB3 mRNA CTD PMID:28659758 NCBI chr 9:60,129,240...60,139,452
Ensembl chr 9:60,129,154...60,139,446 		JBrowse link
G Ndufb5 NADH:ubiquinone oxidoreductase subunit B5 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of NDUFB5 mRNA CTD PMID:28659758 NCBI chr 2:115,519,248...115,533,589
Ensembl chr 2:115,519,154...115,533,589 		JBrowse link
G Ndufs6 NADH:ubiquinone oxidoreductase subunit S6 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of NDUFS6 mRNA CTD PMID:28659758 NCBI chr 1:29,968,833...29,977,423
Ensembl chr 1:29,968,842...29,977,467 		JBrowse link
G Ndufs7 NADH:ubiquinone oxidoreductase core subunit S7 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of NDUFS7 mRNA CTD PMID:28659758 NCBI chr 7:9,452,556...9,460,135
Ensembl chr 7:9,450,392...9,460,195 		JBrowse link
G Ndufs8 NADH:ubiquinone oxidoreductase core subunit S8 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of NDUFS8 mRNA CTD PMID:28659758 NCBI chr 1:201,140,585...201,144,573
Ensembl chr 1:201,140,585...201,144,511 		JBrowse link
G Ndufv1 NADH:ubiquinone oxidoreductase core subunit V1 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of NDUFV1 mRNA CTD PMID:28659758 NCBI chr 1:201,300,365...201,305,461
Ensembl chr 1:201,299,985...201,305,466 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of and affects the localization of NFE2L2 protein CTD PMID:28659758 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of NFKB1 mRNA CTD PMID:28659758 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Ngf nerve growth factor multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of NGF mRNA CTD PMID:28659758 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO NLRP3 protein affects the reaction [[Pyridostigmine Bromide co-treated with Permethrin] results in decreased expression of BDNF protein]; NLRP3 protein affects the reaction [[Pyridostigmine Bromide co-treated with Permethrin] results in increased expression of IL18 protein]; NLRP3 protein affects the reaction [[Pyridostigmine Bromide co-treated with Permethrin] results in increased expression of IL1B protein]; NLRP3 protein affects the reaction [[Pyridostigmine Bromide co-treated with Permethrin] results in increased expression of IL6 protein] CTD PMID:32832901 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of NQO1 mRNA CTD PMID:28659758 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nudt1 nudix hydrolase 1 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of NUDT1 mRNA CTD PMID:28659758 NCBI chr12:14,302,514...14,309,559
Ensembl chr12:14,302,694...14,305,826 		JBrowse link
G Ocln occludin multiple interactions ISO [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in decreased expression of OCLN protein; Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in decreased expression of OCLN protein] CTD PMID:29751049 NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150 		JBrowse link
G Osm oncostatin M multiple interactions ISO [Pyridostigmine Bromide co-treated with DEET] inhibits the reaction [Isoflurophate results in increased expression of OSM mRNA]; [Pyridostigmine Bromide co-treated with DEET] promotes the reaction [CORT protein inhibits the reaction [Isoflurophate results in increased expression of OSM mRNA]] CTD PMID:30339781 NCBI chr14:79,103,638...79,108,500
Ensembl chr14:79,104,344...79,108,313 		JBrowse link
G Park7 Parkinsonism associated deglycase multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of PARK7 mRNA CTD PMID:28659758 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Pfkp phosphofructokinase, platelet multiple interactions ISO [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of PFKP mRNA; Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of PFKP mRNA]; TLR4 gene mutant form inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of PFKP mRNA] CTD PMID:29751049 NCBI chr17:63,729,743...63,794,026
Ensembl chr17:63,729,780...63,794,018 		JBrowse link
G Ppa1 inorganic pyrophosphatase 1 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of PPA1 mRNA CTD PMID:28659758 NCBI chr20:29,590,733...29,617,711
Ensembl chr20:29,590,707...29,619,215 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of PPARA mRNA; Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of PPARA mRNA]; TLR4 gene mutant form inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of PPARA mRNA] CTD PMID:29751049 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in decreased expression of PPARG mRNA; Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in decreased expression of PPARG mRNA] CTD PMID:29751049 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Prdx1 peroxiredoxin 1 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of PRDX1 mRNA CTD PMID:28659758 NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856 		JBrowse link
G Prdx2 peroxiredoxin 2 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of PRDX2 mRNA CTD PMID:28659758 NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194 		JBrowse link
G Prdx5 peroxiredoxin 5 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of PRDX5 mRNA CTD PMID:28659758 NCBI chr 1:204,099,826...204,103,589
Ensembl chr 1:204,099,826...204,114,268 		JBrowse link
G Prdx6 peroxiredoxin 6 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of PRDX6 mRNA CTD PMID:28659758 NCBI chr13:73,528,746...73,539,295
Ensembl chr13:73,528,210...73,539,355 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of PRKACA mRNA CTD PMID:28659758 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430 		JBrowse link
G Prnp prion protein multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of PRNP mRNA CTD PMID:28659758 NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937 		JBrowse link
G Psmb5 proteasome 20S subunit beta 5 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of PSMB5 mRNA CTD PMID:28659758 NCBI chr15:28,072,772...28,077,367
Ensembl chr15:28,072,781...28,077,440 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of PTGS1 mRNA CTD PMID:28659758 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586 		JBrowse link
G Scd stearoyl-CoA desaturase multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of SCD1 mRNA CTD PMID:28659758 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562 		JBrowse link
G Scn11a sodium voltage-gated channel alpha subunit 11 increases expression
multiple interactions		 EXP Pyridostigmine Bromide results in increased expression of SCN11A protein
[Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin co-treated with Chlorpyrifos] results in increased activity of SCN11A protein		 CTD PMID:24732443 PMID:29803855 NCBI chr 8:119,495,550...119,567,044
Ensembl chr 8:119,496,769...119,567,044 		JBrowse link
G Sdhb succinate dehydrogenase complex iron sulfur subunit B multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of SDHB mRNA CTD PMID:28659758 NCBI chr 5:153,264,906...153,285,570
Ensembl chr 5:153,264,899...153,314,293 		JBrowse link
G Selenop selenoprotein P multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of SELENOP mRNA CTD PMID:28659758 NCBI chr 2:52,498,123...52,508,409
Ensembl chr 2:52,498,339...52,508,852 		JBrowse link
G Slc25a10 solute carrier family 25 member 10 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of SLC25A10 mRNA CTD PMID:28659758 NCBI chr10:105,765,598...105,775,159
Ensembl chr10:105,765,372...105,773,556 		JBrowse link
G Slc25a20 solute carrier family 25 member 20 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of SLC25A20 mRNA CTD PMID:28659758 NCBI chr 8:109,365,056...109,386,512
Ensembl chr 8:109,365,002...109,386,512 		JBrowse link
G Slc2a1 solute carrier family 2 member 1 multiple interactions ISO [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of SLC2A1 mRNA; Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of SLC2A1 mRNA]; TLR4 gene mutant form inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of SLC2A1 mRNA] CTD PMID:29751049 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416 		JBrowse link
G Slc2a4 solute carrier family 2 member 4 multiple interactions ISO [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of SLC2A4 mRNA; Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of SLC2A4 mRNA]; TLR4 gene mutant form inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of SLC2A4 mRNA] CTD PMID:29751049 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565 		JBrowse link
G Slc38a1 solute carrier family 38, member 1 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of SLC38A1 mRNA CTD PMID:28659758 NCBI chr 7:127,733,230...127,802,541
Ensembl chr 7:127,738,226...127,802,218 		JBrowse link
G Sod1 superoxide dismutase 1 affects expression
multiple interactions		 ISO Pyridostigmine Bromide affects the expression of SOD1 mRNA
SOD2 protein SNP affects the reaction [Pyridostigmine Bromide affects the expression of SOD1 mRNA]		 CTD PMID:31175926 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
decreases expression		 EXP
ISO		 [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of SOD2 mRNA
SOD2 protein SNP affects the reaction [Pyridostigmine Bromide affects the expression of CASP8 mRNA]; SOD2 protein SNP affects the reaction [Pyridostigmine Bromide affects the expression of SOD1 mRNA]; SOD2 protein SNP affects the reaction [Pyridostigmine Bromide results in decreased expression of BAX mRNA]; SOD2 protein SNP affects the reaction [Pyridostigmine Bromide results in decreased expression of CASP3 mRNA]; SOD2 protein SNP affects the reaction [Pyridostigmine Bromide results in decreased expression of CASP3 protein]; SOD2 protein SNP inhibits the reaction [Pyridostigmine Bromide results in decreased expression of BCL2 mRNA]; SOD2 protein SNP inhibits the reaction [Pyridostigmine Bromide results in decreased expression of CAT mRNA]; SOD2 protein SNP inhibits the reaction [Pyridostigmine Bromide results in decreased expression of DNMT1 mRNA]; SOD2 protein SNP inhibits the reaction [Pyridostigmine Bromide results in decreased expression of GPX1 mRNA]; SOD2 protein SNP inhibits the reaction [Pyridostigmine Bromide results in decreased expression of SOD2 mRNA]; SOD2 protein SNP promotes the reaction [Pyridostigmine Bromide results in decreased expression of ACHE protein]; SOD2 protein SNP promotes the reaction [Pyridostigmine Bromide results in decreased expression of BAX protein]		 CTD PMID:28659758 PMID:31175926 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sod3 superoxide dismutase 3 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of SOD3 mRNA CTD PMID:28659758 NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990 		JBrowse link
G Sqstm1 sequestosome 1 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of SQSTM1 mRNA CTD PMID:28659758 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions ISO [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of SREBF1 mRNA; Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of SREBF1 mRNA]; TLR4 gene mutant form inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of SREBF1 mRNA] CTD PMID:29751049 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650 		JBrowse link
G Srxn1 sulfiredoxin 1 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of SRXN1 mRNA CTD PMID:28659758 NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448 		JBrowse link
G Surf1 SURF1, cytochrome c oxidase assembly factor multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of SURF1 mRNA CTD PMID:28659758 NCBI chr 3:10,241,793...10,244,686
Ensembl chr 3:10,241,837...10,263,315 		JBrowse link
G Syp synaptophysin multiple interactions ISO [Pyridostigmine Bromide co-treated with Permethrin] results in decreased expression of SYP protein CTD PMID:25785457 NCBI chr  X:14,849,444...14,864,553
Ensembl chr  X:14,849,444...14,864,745 		JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of TLR4 protein; Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of TLR4 protein]; TLR4 gene mutant form inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of PFKP mRNA]; TLR4 gene mutant form inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of PPARA mRNA]; TLR4 gene mutant form inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of SLC2A1 mRNA]; TLR4 gene mutant form inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of SLC2A4 mRNA]; TLR4 gene mutant form inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of SREBF1 mRNA]; TLR4 gene mutant form inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of TLR5 protein] CTD PMID:29751049 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tlr5 toll-like receptor 5 multiple interactions ISO [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of TLR5 protein; Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of TLR5 protein]; TLR4 gene mutant form inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of TLR5 protein] CTD PMID:29751049 NCBI chr13:94,634,778...94,658,992
Ensembl chr13:94,634,801...94,657,738 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression		 EXP
ISO		 [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of and results in increased secretion of TNF protein
[Corticosterone co-treated with Pyridostigmine Bromide] results in increased expression of TNF mRNA; [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of TNF mRNA; Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of TNF mRNA]
Pyridostigmine Bromide results in increased expression of TNF mRNA		 CTD PMID:28500787 PMID:28659758 PMID:29751049 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tp53 tumor protein p53 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of TP53 protein CTD PMID:12587291 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Txnrd1 thioredoxin reductase 1 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of TXNRD1 mRNA CTD PMID:28659758 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863 		JBrowse link
G Txnrd2 thioredoxin reductase 2 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of TXNRD2 mRNA CTD PMID:28659758 NCBI chr11:82,519,996...82,568,156
Ensembl chr11:82,519,999...82,568,156 		JBrowse link
G Ucp1 uncoupling protein 1 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of UCP1 mRNA CTD PMID:28659758 NCBI chr19:24,808,782...24,816,853
Ensembl chr19:24,808,783...24,816,852 		JBrowse link
G Ucp2 uncoupling protein 2 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of UCP2 mRNA CTD PMID:28659758 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611 		JBrowse link
G Uqcrb ubiquinol-cytochrome c reductase binding protein multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of UQCRB mRNA CTD PMID:28659758 NCBI chr 7:63,814,784...63,820,150
Ensembl chr 7:63,814,797...63,820,150 		JBrowse link
G Uqcrc1 ubiquinol-cytochrome c reductase core protein 1 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of UQCRC1 mRNA CTD PMID:28659758 NCBI chr 8:109,589,735...109,601,481
Ensembl chr 8:109,589,706...109,601,480 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19899
    chemical entity 19897
      molecular entity 19897
        ion 17101
          anion 16657
            salt 16302
              organic salt 3331
                pyridinium salt 134
                  Pyridostigmine bromide 133
Path 2
Term Annotations click to browse term
  CHEBI ontology 19899
    subatomic particle 19897
      composite particle 19897
        hadron 19897
          baryon 19897
            nucleon 19897
              atomic nucleus 19897
                atom 19897
                  main group element atom 19835
                    p-block element atom 19835
                      carbon group element atom 19776
                        carbon atom 19772
                          organic molecular entity 19772
                            organic molecule 19724
                              organic cyclic compound 19514
                                organic heterocyclic compound 18893
                                  organic heteromonocyclic compound 17817
                                    pyridines 11529
                                      pyridinium salt 134
                                        Pyridostigmine bromide 133
paths to the root