imidazole antifungal agent - Ontology Report - Rat Genome Database

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	imidazole antifungal agent	go back to main search page
Accession:	CHEBI:86420	browse the term
Definition:	A compound that has significant antifungal properties whose structure contains an imidazole moiety.
Synonyms:	related_synonym:	imidazole antifungal agents

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Rat (1997) Mouse (2009) Human (2000) Chinchilla (0) Bonobo (0) Dog (6) Squirrel (0) Pig (1) Green Monkey (0) Naked Mole-rat (0) All
Genes (1997)

bifonazole

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

cytochrome P450, family 19, subfamily a, polypeptide 1

decreases activity

bifonazole results in decreased activity of CYP19A1 protein

PMID:15554355 PMID:24496634

NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758

G

cytochrome P450, family 3, subfamily a, polypeptide 2

decreases activity

bifonazole results in decreased activity of CYP3A4 protein

NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008

G

cytochrome P450, family 51

decreases activity

bifonazole results in decreased activity of CYP51A1 protein

NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410
Ensembl chr 6:30,036,865...30,055,410

butoconazole

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

potassium voltage-gated channel subfamily H member 2

decreases activity

butoconazole results in decreased activity of KCNH2 protein

NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008

G

nuclear receptor subfamily 1, group I, member 2

increases activity

butoconazole results in increased activity of NR1I2 protein

NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658

climbazole

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

cytochrome P450, family 2, subfamily b, polypeptide 1

increases expression

climbazole results in increased expression of CYP2B1 mRNA; climbazole results in increased expression of CYP2B1 protein

PMID:11552297 PMID:11824557

NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052

G

cytochrome P450, family 3, subfamily a, polypeptide 2

increases expression

climbazole results in increased expression of CYP3A2 protein

PMID:11552297 PMID:11824557

NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008

G

cytochrome P450, family 4, subfamily a, polypeptide 1

increases expression

climbazole results in increased expression of CYP4A1 protein

NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464

clotrimazole

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily B member 11

multiple interactions
decreases activity

Clotrimazole inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
Clotrimazole results in decreased activity of ABCB11 protein

NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730

G

ATP binding cassette subfamily B member 1A

affects binding
multiple interactions
increases expression

Clotrimazole binds to ABCB1 protein
Clotrimazole inhibits the reaction [ABCB1A protein results in increased secretion of fluorexon]
Clotrimazole results in increased expression of ABCB1 protein
Clotrimazole inhibits the reaction [ABCB1 protein results in increased export of Doxorubicin]; Clotrimazole inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]; Clotrimazole inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]

PMID:8632764 PMID:8917702 PMID:12235267

NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709

G

ATP binding cassette subfamily C member 2

increases expression

Clotrimazole results in increased expression of ABCC2 mRNA; Clotrimazole results in increased expression of ABCC2 protein

NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238

G

ATP binding cassette subfamily C member 3

multiple interactions
increases expression

MAPK14 promotes the reaction [Clotrimazole results in increased expression of ABCC3 mRNA]; SB 203580 inhibits the reaction [Clotrimazole results in increased expression of ABCC3 mRNA]

NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595

G

acid phosphatase 2, lysosomal

increases expression

Clotrimazole results in increased expression of ACP2 mRNA

NCBI chr 3:77,175,022...77,185,180
Ensembl chr 3:77,175,895...77,185,680

G

ADAM metallopeptidase domain 22

decreases expression

Clotrimazole results in decreased expression of ADAM22 mRNA

NCBI chr 4:25,716,055...25,970,932
Ensembl chr 4:25,715,990...25,964,962

G

ADAM metallopeptidase with thrombospondin type 1 motif, 12

decreases expression

Clotrimazole results in decreased expression of ADAMTS12 mRNA

NCBI chr 2:60,032,873...60,327,629
Ensembl chr 2:60,032,873...60,327,629

G

ADAM metallopeptidase with thrombospondin type 1 motif, 7

increases expression

Clotrimazole results in increased expression of ADAMTS7 mRNA

NCBI chr 8:90,704,727...90,744,333
Ensembl chr 8:90,704,727...90,744,328

G

ADAMTS-like 5

decreases expression

Clotrimazole results in decreased expression of ADAMTSL5 mRNA

NCBI chr 7:9,362,623...9,371,248
Ensembl chr 7:9,363,237...9,370,285

G

adenosine deaminase, RNA-specific

decreases expression

Clotrimazole results in decreased expression of ADAR mRNA

NCBI chr 2:175,138,391...175,178,280
Ensembl chr 2:175,138,403...175,178,282

G

adenylate cyclase 9

decreases activity

Clotrimazole results in decreased activity of ADCY9 protein

NCBI chr10:11,138,966...11,262,067
Ensembl chr10:11,139,446...11,262,066

G

adenosine A2a receptor

increases expression

Clotrimazole results in increased expression of ADORA2A mRNA

NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386

G

AE binding protein 1

increases expression

Clotrimazole results in increased expression of AEBP1 mRNA

NCBI chr14:80,738,800...80,748,878
Ensembl chr14:80,738,892...80,748,877

G

ArfGAP with FG repeats 1

increases expression

Clotrimazole results in increased expression of AGFG1 mRNA

NCBI chr 9:84,124,845...84,182,615
Ensembl chr 9:84,125,120...84,178,128

G

aryl hydrocarbon receptor

increases activity

Clotrimazole results in increased activity of AHR protein

NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568

G

adenylate kinase 6

increases expression

Clotrimazole results in increased expression of AK6 mRNA

NCBI chr 2:31,794,316...31,806,375
Ensembl chr 2:31,794,519...31,806,371
Ensembl chr20:31,794,519...31,806,371

G

aldehyde dehydrogenase 9 family, member A1

increases expression

Clotrimazole results in increased expression of ALDH9A1 mRNA

NCBI chr13:79,505,738...79,522,539
Ensembl chr13:79,505,695...79,540,568

G

aldolase, fructose-bisphosphate B

affects localization

Clotrimazole affects the localization of ALDOB protein

NCBI chr 5:63,889,045...63,902,086
Ensembl chr 5:63,889,046...63,902,116

G

ankyrin repeat domain 40

increases expression

Clotrimazole results in increased expression of ANKRD40 mRNA

NCBI chr10:79,282,075...79,295,322
Ensembl chr10:79,282,075...79,295,320
Ensembl chr10:79,282,075...79,295,320

G

apolipoprotein E

decreases expression

Clotrimazole results in decreased expression of APOE mRNA

NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932

G

arrestin domain containing 1

decreases expression

Clotrimazole results in decreased expression of ARRDC1 mRNA

NCBI chr 3:7,735,002...7,742,195
Ensembl chr 3:7,735,011...7,742,197

G

activating transcription factor 3

increases expression
multiple interactions

Clotrimazole results in increased expression of ATF3 mRNA
SB 203580 inhibits the reaction [Clotrimazole results in increased expression of ATF3 mRNA]

PMID:27507784 PMID:27965148

NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631

G

ATP synthase F1 subunit gamma

increases expression

Clotrimazole results in increased expression of ATP5F1C mRNA

NCBI chr17:68,423,927...68,446,169
Ensembl chr17:68,423,909...68,608,367

G

ATP synthase peripheral stalk-membrane subunit b

increases expression

Clotrimazole results in increased expression of ATP5PB mRNA

NCBI chr 2:193,424,138...193,435,418
Ensembl chr 2:193,424,047...193,435,418

G

ATP synthase peripheral stalk subunit d

increases expression

Clotrimazole results in increased expression of ATP5PD mRNA

NCBI chr10:100,657,700...100,662,960
Ensembl chr10:100,657,708...100,663,479

G

ATP synthase mitochondrial F1 complex assembly factor 2

increases expression

Clotrimazole results in increased expression of ATPAF2 mRNA

NCBI chr10:45,205,658...45,221,891
Ensembl chr10:45,197,441...45,221,026

G

5-azacytidine induced 2

increases expression

Clotrimazole results in increased expression of AZI2 mRNA

NCBI chr 8:117,773,248...117,797,844
Ensembl chr 8:117,773,279...117,797,847

G

basic leucine zipper ATF-like transcription factor 3

increases expression

Clotrimazole results in increased expression of BATF3 mRNA

NCBI chr13:102,689,657...102,701,241
Ensembl chr13:102,689,657...102,701,139

G

Bardet-Biedl syndrome 4

decreases expression

Clotrimazole results in decreased expression of BBS4 mRNA

NCBI chr 8:59,731,912...59,765,408
Ensembl chr 8:59,731,912...59,765,607

G

branched chain keto acid dehydrogenase E1 subunit alpha

decreases expression

Clotrimazole results in decreased expression of BCKDHA mRNA

NCBI chr 1:81,138,946...81,167,765
Ensembl chr 1:81,138,947...81,167,862

G

basic helix-loop-helix family, member e22

decreases expression

Clotrimazole results in decreased expression of BHLHE22 mRNA

NCBI chr 2:100,486,400...100,489,510
Ensembl chr 2:100,486,400...100,489,510

G

BICD cargo adaptor 2

increases expression

Clotrimazole results in increased expression of BICD2 mRNA

NCBI chr17:15,259,773...15,304,889
Ensembl chr17:15,259,773...15,304,889

G

Bri3 binding protein

increases expression

Clotrimazole results in increased expression of BRI3BP mRNA

NCBI chr12:31,176,742...31,188,563
Ensembl chr12:31,173,971...31,188,572

G

basic transcription factor 3

decreases expression

Clotrimazole results in decreased expression of BTF3 mRNA

NCBI chr 2:29,659,764...29,666,898
Ensembl chr 2:29,659,231...29,666,879
Ensembl chr13:29,659,231...29,666,879

G

C1q and TNF related 1

decreases expression

Clotrimazole results in decreased expression of C1QTNF1 mRNA

NCBI chr10:103,660,319...103,681,662
Ensembl chr10:103,660,327...103,681,660

G

C1q and TNF related 5

increases expression

Clotrimazole results in increased expression of C1QTNF5 mRNA

NCBI chr 8:44,450,934...44,453,075
Ensembl chr 8:44,451,154...44,453,074

G

calcium voltage-gated channel auxiliary subunit beta 1

decreases expression

Clotrimazole results in decreased expression of CACNB1 mRNA

NCBI chr10:82,998,182...83,018,838
Ensembl chr10:82,998,182...83,018,694

G

calreticulin

increases expression

Clotrimazole results in increased expression of CALR mRNA

NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414

G

caspase 12

decreases expression

Clotrimazole results in decreased expression of CASP12 mRNA

NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037

G

caspase 3

multiple interactions

Clotrimazole inhibits the reaction [Benzo(a)pyrene results in increased expression of CASP3 mRNA]
[S-allylcysteine co-treated with Clotrimazole] inhibits the reaction [lead acetate results in increased activity of CASP3 protein]; Clotrimazole inhibits the reaction [lead acetate results in increased activity of CASP3 protein]

PMID:22033380 PMID:24239969

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

caspase 8

multiple interactions

[S-allylcysteine co-treated with Clotrimazole] inhibits the reaction [lead acetate results in increased activity of CASP8 protein]; Clotrimazole inhibits the reaction [lead acetate results in increased activity of CASP8 protein]

NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542

G

catalase

multiple interactions

[S-allylcysteine co-treated with Clotrimazole] inhibits the reaction [lead acetate results in decreased activity of CAT protein]; Clotrimazole inhibits the reaction [lead acetate results in decreased activity of CAT protein]

NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478

G

coiled-coil domain containing 17

decreases expression

Clotrimazole results in decreased expression of CCDC17 mRNA

NCBI chr 5:130,051,158...130,056,676
Ensembl chr 5:130,045,938...130,056,673

G

coiled-coil domain containing 28A

decreases expression

Clotrimazole results in decreased expression of CCDC28A mRNA

NCBI chr 1:12,857,668...12,872,944
Ensembl chr 1:12,857,666...12,873,003

G

centriole, cilia and spindle-associated protein

decreases expression

Clotrimazole results in decreased expression of CCSAP mRNA

NCBI chr19:51,824,954...51,843,469
Ensembl chr19:51,826,994...51,842,753

G

Cd81 molecule

increases expression

Clotrimazole results in increased expression of CD81 mRNA

NCBI chr 1:198,235,861...198,251,660
Ensembl chr 1:198,241,484...198,251,660

G

CD93 molecule

increases expression

Clotrimazole results in increased expression of CD93 mRNA

NCBI chr 3:135,891,859...135,898,378
Ensembl chr 3:135,891,859...135,898,378

G

cell death-inducing p53 target 1

decreases expression

Clotrimazole results in decreased expression of CDIP1 mRNA

NCBI chr10:10,773,538...10,796,979
Ensembl chr10:10,774,705...10,796,980

G

cyclin-dependent kinase 1

decreases expression

Clotrimazole results in decreased expression of CDK1

NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408

G

cyclin-dependent kinase 4

decreases expression

Clotrimazole results in decreased expression of CDK4

NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403

G

cyclin-dependent kinase inhibitor 1A

decreases expression

Clotrimazole results in decreased expression of CDKN1A

NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585

G

cyclin-dependent kinase inhibitor 1B

increases expression

Clotrimazole results in increased expression of CDKN1B

NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982

G

CDKN2A interacting protein

decreases expression

Clotrimazole results in decreased expression of CDKN2AIP mRNA

NCBI chr16:44,536,147...44,546,216
Ensembl chr16:44,536,234...44,540,033

G

centromere protein J

decreases expression

Clotrimazole results in decreased expression of CPAP mRNA

NCBI chr15:30,627,206...30,690,384
Ensembl chr15:30,627,224...30,686,791

G

coiled-coil-helix-coiled-coil-helix domain containing 1

increases expression

Clotrimazole results in increased expression of CHCHD1 mRNA

NCBI chr15:3,592,719...3,593,901
Ensembl chr15:3,592,727...3,593,901

G

chromodomain helicase DNA binding protein 2

decreases expression

Clotrimazole results in decreased expression of CHD2 mRNA

NCBI chr 1:127,188,146...127,317,041
Ensembl chr 1:127,190,059...127,300,502

G

carbohydrate sulfotransferase 1

increases expression

Clotrimazole results in increased expression of CHST1 mRNA

NCBI chr 3:78,552,059...78,574,740
Ensembl chr 3:78,548,525...78,574,883

G

ciliary microtubule associated protein 1C

increases expression

Clotrimazole results in increased expression of CIMAP1C mRNA

NCBI chr 8:57,248,746...57,281,084
Ensembl chr 8:57,248,746...57,281,004

G

CDGSH iron sulfur domain 2

increases expression

Clotrimazole results in increased expression of CISD2 mRNA

NCBI chr 2:223,828,937...223,853,768
Ensembl chr 2:223,828,937...223,868,946

G

chloride voltage-gated channel 3

increases expression

Clotrimazole results in increased expression of CLCN3 mRNA

NCBI chr16:29,127,152...29,200,133
Ensembl chr16:29,127,419...29,200,119

G

CDC-like kinase 2

decreases expression

Clotrimazole results in decreased expression of CLK2 mRNA

NCBI chr 2:174,570,614...174,582,645
Ensembl chr 2:174,570,653...174,588,985

G

calponin 2

increases expression

Clotrimazole results in increased expression of CNN2 mRNA

NCBI chr 7:9,712,505...9,719,678
Ensembl chr 7:9,712,516...9,719,656

G

collagen type I alpha 1 chain

decreases expression

Clotrimazole results in decreased expression of COL1A1 mRNA

NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624

G

collagen type VI alpha 2 chain

increases expression

Clotrimazole results in increased expression of COL6A2 mRNA

NCBI chr20:12,021,676...12,049,425
Ensembl chr20:12,021,767...12,057,564

G

collagen type VII alpha 1 chain

decreases expression

Clotrimazole results in decreased expression of COL7A1 mRNA

NCBI chr 8:109,604,877...109,637,249
Ensembl chr 8:109,604,861...109,637,252

G

collagen type IX alpha 2 chain

decreases expression

Clotrimazole results in decreased expression of COL9A2 mRNA

NCBI chr 5:134,607,616...134,624,678
Ensembl chr 5:134,607,616...134,624,677

G

COMM domain containing 2

increases expression

Clotrimazole results in increased expression of COMMD2 mRNA

NCBI chr 2:141,848,661...141,852,907
Ensembl chr 2:141,848,680...141,852,888

G

coronin 2B

increases expression

Clotrimazole results in increased expression of CORO2B mRNA

NCBI chr 8:62,906,861...63,017,295
Ensembl chr 8:62,906,867...63,017,302

G

cytochrome c oxidase subunit 7A2

increases expression

Clotrimazole results in increased expression of COX7A2 mRNA

NCBI chr 8:80,716,824...80,720,922
Ensembl chr14:51,301,168...51,301,633
Ensembl chr 8:51,301,168...51,301,633

G

cytochrome c oxidase subunit 8A

increases expression

Clotrimazole results in increased expression of COX8A mRNA

NCBI chr 1:204,402,118...204,404,439

G

carboxypeptidase Z

decreases expression

Clotrimazole results in decreased expression of CPZ mRNA

NCBI chr14:75,223,692...75,246,946
Ensembl chr14:75,223,605...75,246,945

G

cAMP responsive element binding protein 3-like 2

increases expression

Clotrimazole results in increased expression of CREB3L2 mRNA

NCBI chr 4:65,907,570...66,112,078
Ensembl chr 4:65,907,655...66,023,763

G

cysteine-rich secretory protein 1

decreases expression

Clotrimazole results in decreased expression of CRISP1 mRNA

NCBI chr 9:20,741,775...20,768,796
Ensembl chr 9:20,741,777...20,768,796

G

cytochrome P450, family 17, subfamily a, polypeptide 1

decreases activity

Clotrimazole results in decreased activity of CYP17A1 protein

NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573

G

cytochrome P450, family 19, subfamily a, polypeptide 1

decreases activity

Clotrimazole results in decreased activity of CYP19A1 protein

NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758

G

cytochrome P450, family 1, subfamily a, polypeptide 1

increases expression
decreases activity

Clotrimazole results in increased expression of CYP1A1 protein
Clotrimazole results in decreased activity of CYP1A1 protein

PMID:7986207 PMID:33814510

NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125

G

cytochrome P450, family 1, subfamily a, polypeptide 2

increases expression
multiple interactions

Clotrimazole results in increased expression of CYP1A2 protein
Clotrimazole inhibits the reaction [CYP1A2 protein results in increased metabolism of 3-cyano-7-ethoxycoumarin]

PMID:7986207 PMID:19858067

NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312

G

cytochrome P450, family 1, subfamily b, polypeptide 1

decreases activity

Clotrimazole results in decreased activity of CYP1B1 protein

NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917

G

cytochrome P450, family 2, subfamily a, polypeptide 2

multiple interactions

Clotrimazole inhibits the reaction [CYP2A2 protein results in increased metabolism of 7-benzyloxyquinoline]

NCBI chr 1:82,263,833...82,289,487
Ensembl chr 1:82,263,833...82,289,487

G

cytochrome P450, family 2, subfamily b, polypeptide 1

multiple interactions
increases activity
increases expression

Clotrimazole inhibits the reaction [CYP2B1 protein results in increased metabolism of 7-benzyloxy-4-trifluoromethylcoumarin]
Clotrimazole results in increased activity of CYP2B1 protein
Clotrimazole results in increased expression of CYP2B1 mRNA; Clotrimazole results in increased expression of CYP2B1 protein

PMID:1372805 PMID:7986207 PMID:19858067 PMID:36356836

NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052

G

cytochrome P450, family 2, subfamily b, polypeptide 2

increases expression

Clotrimazole results in increased expression of CYP2B2 mRNA; Clotrimazole results in increased expression of CYP2B2 protein

PMID:7986207 PMID:12971794

NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566

G

cytochrome P450, family 2, subfamily b, polypeptide 3

multiple interactions
increases expression
increases activity

Clotrimazole results in increased expression of and results in increased activity of CYP2B6 protein; Dexamethasone promotes the reaction [NR3C1 protein affects the reaction [NR1I2 protein promotes the reaction [Clotrimazole results in increased expression of CYP2B6 mRNA]]]; NR1I2 protein affects the reaction [Clotrimazole results in increased expression of and results in increased activity of CYP2B6 protein]; NR1I2 protein promotes the reaction [Clotrimazole results in increased expression of CYP2B6 mRNA]
NR1I3 protein affects the reaction [Clotrimazole results in increased expression of CYP2B10 mRNA]
Clotrimazole results in increased expression of CYP2B6 protein
Clotrimazole results in increased activity of CYP2B6 protein

PMID:12049174 PMID:12571232 PMID:12695351 PMID:14977870

NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143

G

cytochrome P450, subfamily 2, polypeptide 11

multiple interactions
decreases expression

Clotrimazole inhibits the reaction [CYP2C11 protein results in increased metabolism of 7-methoxy-4-trifluoromethylcoumarin]
Clotrimazole results in decreased expression of CYP2C11 protein

PMID:7986207 PMID:19858067

NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066

G

cytochrome P450, family 2, subfamily C, polypeptide 6

multiple interactions

Clotrimazole inhibits the reaction [CYP2C6 protein results in increased metabolism of 7-methoxy-4-trifluoromethylcoumarin]

NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596

G

cytochrome P450, family 2, subfamily c, polypeptide 79

decreases activity

Clotrimazole results in decreased activity of CYP2C8 protein

PMID:15601807 PMID:33775687

G

cytochrome P450, family 2, subfamily d, polypeptide 2

multiple interactions

Clotrimazole inhibits the reaction [CYP2D2 protein results in increased metabolism of 3-(2-(N,N-diethyl-N-methylammonium)ethyl)-7-methoxy-4-methylcoumarin]

NCBI chr 7:113,935,138...113,939,209
Ensembl chr 7:113,935,138...113,939,209

G

cytochrome P450, family 2, subfamily j, polypeptide 3

decreases expression

Clotrimazole results in decreased expression of CYP2J3 mRNA

NCBI chr 5:111,219,921...111,244,987
Ensembl chr 5:111,178,703...111,244,794

G

cytochrome P450, family 3, subfamily a, polypeptide 2

multiple interactions
decreases activity
increases expression
increases activity

Clotrimazole inhibits the reaction [CYP3A2 protein results in increased metabolism of 7-benzyloxyquinoline]
Clotrimazole inhibits the reaction [CYP3A4 protein results in increased oxidation of 7-benzyloxy-4-trifluoromethylcoumarin]; Clotrimazole promotes the reaction [NR1I2 results in increased expression of CYP3A4 mRNA]; NR1I2 protein promotes the reaction [Clotrimazole results in increased expression of CYP3A4 mRNA]
Clotrimazole results in decreased activity of CYP3A4 protein
Clotrimazole results in increased expression of CYP3A4 mRNA; Clotrimazole results in increased expression of CYP3A4 protein
Clotrimazole results in increased activity of CYP3A4 protein

PMID:8632764 PMID:12065438 PMID:12505310 PMID:12673034 PMID:14977870 More...

NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008

G

cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1

increases expression
multiple interactions

Clotrimazole results in increased expression of CYP3A23-3A1 mRNA
Clotrimazole inhibits the reaction [CYP3A23-3A1 protein results in increased metabolism of 7-benzyloxyquinoline]

PMID:12971794 PMID:16125621 PMID:19858067

NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030

G

cytochrome P450, family 3, subfamily a, polypeptide 9

increases expression

Clotrimazole results in increased expression of CYP3A5 protein

NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422

G

cytochrome P450, family 51

decreases activity
decreases response to substance

Clotrimazole results in decreased activity of CYP51A1 protein
CYP51A1 gene results in decreased susceptibility to Clotrimazole

PMID:16989930 PMID:18694951

NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410
Ensembl chr 6:30,036,865...30,055,410

G

DAB adaptor protein 2

increases expression

Clotrimazole results in increased expression of DAB2 mRNA

NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476

G

drebrin 1

increases expression

Clotrimazole results in increased expression of DBN1 mRNA

NCBI chr17:9,150,608...9,164,982
Ensembl chr17:9,150,659...9,164,984

G

dachsous cadherin-related 1

increases expression

Clotrimazole results in increased expression of DCHS1 mRNA

NCBI chr 1:160,104,931...160,138,958
Ensembl chr 1:160,104,931...160,124,808

G

doublecortin-like kinase 1

decreases expression

Clotrimazole results in decreased expression of DCLK1 mRNA

NCBI chr 2:139,417,234...139,710,956
Ensembl chr 2:139,417,163...139,710,956

G

DExD-box helicase 39A

increases expression

Clotrimazole results in increased expression of DDX39A mRNA

NCBI chr19:24,418,743...24,427,422
Ensembl chr19:24,418,114...24,426,954

G

DnaJ heat shock protein family (Hsp40) member B4

increases expression

Clotrimazole results in increased expression of DNAJB4 mRNA

NCBI chr 2:241,129,346...241,159,272
Ensembl chr 2:241,130,340...241,159,089

G

double C2 domain beta

increases expression

Clotrimazole results in increased expression of DOC2B mRNA

NCBI chr10:60,628,029...60,653,267
Ensembl chr10:60,628,029...60,653,267

G

docking protein 4

increases expression

Clotrimazole results in increased expression of DOK4 mRNA

NCBI chr19:10,146,520...10,157,187
Ensembl chr19:10,146,474...10,158,203

G

diphthamide biosynthesis 3

increases expression

Clotrimazole results in increased expression of DPH3 mRNA

NCBI chr16:7,288,295...7,293,734
Ensembl chr16:7,282,705...7,291,265

G

dolichyl-phosphate mannosyltransferase subunit 1, catalytic

increases expression

Clotrimazole results in increased expression of DPM1 mRNA

NCBI chr 3:156,919,979...156,939,522
Ensembl chr 3:156,919,979...156,939,536

G

DS cell adhesion molecule

decreases expression

Clotrimazole results in decreased expression of DSCAM mRNA

NCBI chr11:35,921,924...36,507,100
Ensembl chr11:35,926,896...36,507,415

G

EP300 interacting inhibitor of differentiation 2

increases expression

Clotrimazole results in increased expression of EID2 mRNA

NCBI chr 1:83,538,274...83,539,599

G

eukaryotic translation initiation factor 2A

multiple interactions
increases phosphorylation

[Clotrimazole results in increased phosphorylation of EIF2A protein] which results in increased expression of TMEFF2 protein

NCBI chr 2:142,761,303...142,794,767
Ensembl chr 2:142,761,416...142,795,068

G

endoglin

increases expression

Clotrimazole results in increased expression of ENG mRNA

NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230

G

erythrocyte membrane protein band 4.1-like 2

increases expression

Clotrimazole results in increased expression of EPB41L2 mRNA

NCBI chr 1:19,863,010...20,037,795
Ensembl chr 1:19,863,009...20,037,721

G

epoxide hydrolase 1

increases activity

Clotrimazole results in increased activity of EPHX1 protein

NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235

G

EPS8-like 1

decreases expression

Clotrimazole results in decreased expression of EPS8L1 mRNA

NCBI chr 1:69,343,202...69,359,778
Ensembl chr 1:69,344,243...69,363,524

G

endoplasmic reticulum to nucleus signaling 1

decreases expression

Clotrimazole results in decreased expression of ERN1 mRNA

NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029

G

endothelial cell adhesion molecule

increases expression

Clotrimazole results in increased expression of ESAM mRNA

NCBI chr 8:37,238,228...37,249,217
Ensembl chr 8:37,238,287...37,249,215

G

F2R like trypsin receptor 1

multiple interactions

Clotrimazole inhibits the reaction [F2RL1 protein results in increased transport of Chlorides]

NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226

G

family with sequence similarity 110, member B

decreases expression

Clotrimazole results in decreased expression of FAM110B mRNA

NCBI chr 5:18,789,362...18,929,647
Ensembl chr 5:18,789,389...18,929,828

G

family with sequence similarity 120 member B

increases expression

Clotrimazole results in increased expression of FAM120B mRNA

NCBI chr 1:56,320,015...56,385,064
Ensembl chr 1:56,339,129...56,385,061

G

family with sequence similarity 124 member A

decreases expression

Clotrimazole results in decreased expression of FAM124A mRNA

NCBI chr15:36,799,836...36,855,062
Ensembl chr15:36,799,877...36,853,683

G

family with sequence similarity 167, member B

increases expression

Clotrimazole results in increased expression of FAM167B mRNA

NCBI chr 5:141,920,695...141,922,342
Ensembl chr 5:141,920,695...141,922,340

G

FA complementation group I

increases expression

Clotrimazole results in increased expression of FANCI mRNA

NCBI chr 1:133,327,264...133,383,661
Ensembl chr 1:133,327,297...133,383,640

G

Fas cell surface death receptor

multiple interactions

[S-allylcysteine co-treated with Clotrimazole] inhibits the reaction [lead acetate affects the localization of and results in increased activity of FAS protein]

NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591

G

four and a half LIM domains 2

increases expression

Clotrimazole results in increased expression of FHL2 mRNA

NCBI chr 9:45,388,979...45,462,421
Ensembl chr 9:45,388,981...45,431,192

G

Fos proto-oncogene, AP-1 transcription factor subunit

decreases expression

Clotrimazole results in decreased expression of FOS protein

NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036

G

follistatin-like 1

increases expression

Clotrimazole results in increased expression of FSTL1 mRNA

NCBI chr11:62,895,391...62,948,581
Ensembl chr11:62,779,783...62,948,677

G

FXYD domain-containing ion transport regulator 5

increases expression

Clotrimazole results in increased expression of FXYD5 mRNA

NCBI chr 1:86,267,937...86,277,329
Ensembl chr 1:86,267,406...86,277,519

G

galanin receptor 2

decreases expression

Clotrimazole results in decreased expression of GALR2 mRNA

NCBI chr10:101,513,689...101,517,176
Ensembl chr10:101,514,471...101,517,176

G

glucosidase, alpha; neutral C

decreases expression

Clotrimazole results in decreased expression of GANC mRNA

NCBI chr 3:107,353,369...107,406,104
Ensembl chr 3:107,353,369...107,405,241

G

growth associated protein 43

decreases expression

Clotrimazole results in decreased expression of GAP43 mRNA

NCBI chr11:58,376,371...58,470,047
Ensembl chr11:58,376,371...58,470,045

G

golgi associated RAB2 interactor 5A

decreases expression

Clotrimazole results in decreased expression of FAM71E1 mRNA

NCBI chr 1:94,988,959...94,995,971
Ensembl chr 1:94,988,613...94,993,539

G

gem (nuclear organelle) associated protein 7-like 1

increases expression

Clotrimazole results in increased expression of GEMIN7L1 mRNA

NCBI chr 4:78,269,910...78,270,681
Ensembl chr 4:78,269,888...78,270,669

G

glial fibrillary acidic protein

increases expression

Clotrimazole results in increased expression of GFAP protein

NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589

G

gliomedin

decreases expression

Clotrimazole results in decreased expression of GLDN mRNA

NCBI chr 8:54,679,015...54,723,198
Ensembl chr 8:54,679,119...54,723,196

G

glutaredoxin 2

increases expression

Clotrimazole results in increased expression of GLRX2 mRNA

NCBI chr13:55,481,875...55,504,737
Ensembl chr13:55,482,694...55,492,831

G

glutamic-oxaloacetic transaminase 1

multiple interactions

[S-allylcysteine co-treated with Clotrimazole] inhibits the reaction [lead acetate results in increased expression of GOT1 protein]

NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633

G

glypican 3

decreases expression

Clotrimazole results in decreased expression of GPC3 mRNA

NCBI chr X:131,868,986...132,236,824
Ensembl chr X:131,868,990...132,236,798

G

G protein-coupled receptor 62

decreases expression

Clotrimazole results in decreased expression of GPR62 mRNA

NCBI chr 8:107,103,225...107,105,311
Ensembl chr 8:107,103,980...107,105,056

G

glutamic--pyruvic transaminase

multiple interactions

[S-allylcysteine co-treated with Clotrimazole] inhibits the reaction [lead acetate results in increased expression of GPT protein]

NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494

G

GRAM domain containing 1A

decreases expression

Clotrimazole results in decreased expression of GRAMD1A mRNA

NCBI chr 1:86,367,001...86,393,348
Ensembl chr 1:86,367,001...86,393,336

G

glutamate ionotropic receptor NMDA type subunit associated protein 1

increases expression

Clotrimazole results in increased expression of GRINA mRNA

NCBI chr 7:107,962,194...107,965,372
Ensembl chr 7:107,962,207...107,965,366

G

Gse1 coiled-coil protein

decreases expression

Clotrimazole results in decreased expression of GSE1 mRNA

NCBI chr19:48,274,164...48,629,456
Ensembl chr19:48,274,127...48,629,458

G

glutathione S-transferase alpha 2

increases expression

Clotrimazole results in increased expression of GSTA2 mRNA

NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798

G

glutathione S-transferase mu 2

decreases expression

Clotrimazole results in decreased expression of GSTM2 mRNA

NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961

G

glutathione S-transferase pi 1

multiple interactions

Clotrimazole inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate]

NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226

G

guanylate cyclase activator 1A

increases expression

Clotrimazole results in increased expression of GUCA1A mRNA

NCBI chr 9:13,588,988...13,598,566
Ensembl chr 9:13,588,525...13,598,565

G

guanylate cyclase 1 soluble subunit alpha 1

increases expression

Clotrimazole results in increased expression of GUCY1A3 mRNA

NCBI chr 2:167,418,615...167,482,293
Ensembl chr 2:167,418,640...167,481,671

G

HECT and RLD domain containing E3 ubiquitin protein ligase family member 1

decreases expression

Clotrimazole results in decreased expression of HERC1 mRNA

NCBI chr 8:66,857,169...67,070,318
Ensembl chr 8:66,856,935...67,070,312

G

huntingtin interacting protein 1

increases expression

Clotrimazole results in increased expression of HIP1 mRNA

NCBI chr12:21,133,364...21,267,796
Ensembl chr12:21,133,406...21,267,725

G

histone cluster 1 H2B family member D

increases expression

Clotrimazole results in increased expression of HIST1H2BD mRNA

NCBI chr17:42,792,887...42,793,268

G

hexokinase 2

affects localization
decreases expression

Clotrimazole affects the localization of HK2 protein
Clotrimazole results in decreased expression of HK2 mRNA

PMID:20724915 PMID:25863232

NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530

G

high mobility group box 1

increases expression

Clotrimazole results in increased expression of HMGB1 mRNA

NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565

G

HPS4, biogenesis of lysosomal organelles complex 3 subunit 2

decreases expression

Clotrimazole results in decreased expression of HPS4 mRNA

NCBI chr12:44,264,037...44,294,791
Ensembl chr12:44,264,037...44,294,632

G

heat shock transcription factor 1

increases activity

Clotrimazole results in increased activity of HSF1 protein

NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011

G

heat shock protein family A (Hsp70) member 4

increases expression

Clotrimazole results in increased expression of HSPA4 mRNA

NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001

G

heat shock protein family E (Hsp10) member 1

increases expression

Clotrimazole results in increased expression of HSPE1 mRNA

NCBI chr 9:56,589,912...56,593,000
Ensembl chr 9:56,589,789...56,593,089

G

interferon-induced protein 44

decreases expression

Clotrimazole results in decreased expression of IFI44 mRNA

NCBI chr 2:240,626,058...240,643,879
Ensembl chr 2:240,626,066...240,643,844

G

interferon alpha and beta receptor subunit 2

decreases expression

Clotrimazole results in decreased expression of IFNAR2 mRNA

NCBI chr11:30,613,576...30,645,958
Ensembl chr11:30,613,767...30,668,124

G

insulin-like growth factor 2 mRNA binding protein 2

increases expression

Clotrimazole results in increased expression of IGF2BP2 mRNA

NCBI chr11:78,874,402...78,974,392
Ensembl chr11:78,874,414...78,974,377

G

insulin-like growth factor binding protein 1

increases expression
increases secretion

Clotrimazole results in increased expression of IGFBP1 mRNA
Clotrimazole results in increased secretion of IGFBP1 protein

NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482

G

immunoglobulin superfamily, member 10

decreases expression

Clotrimazole results in decreased expression of IGSF10 mRNA

NCBI chr 2:143,575,710...143,605,044
Ensembl chr 2:143,576,070...143,604,773

G

interleukin 34

increases expression

Clotrimazole results in increased expression of IL34 mRNA

NCBI chr19:38,714,990...38,782,749
Ensembl chr19:38,714,991...38,764,000

G

inositol polyphosphate-5-phosphatase D

increases expression

Clotrimazole results in increased expression of INPP5D mRNA

NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746

G

integrator complex subunit 14

increases expression

Clotrimazole results in increased expression of VWA9 mRNA

NCBI chr 8:65,475,788...65,500,807
Ensembl chr 8:65,475,910...65,500,804

G

inositol hexakisphosphate kinase 2

decreases expression

Clotrimazole results in decreased expression of IP6K2 mRNA

NCBI chr 8:109,483,843...109,510,172
Ensembl chr 8:109,484,310...109,510,166

G

integrin subunit alpha 9

increases expression

Clotrimazole results in increased expression of ITGA9 mRNA

NCBI chr 8:118,307,424...118,615,527
Ensembl chr 8:118,307,381...118,613,754

G

integrin subunit beta 1

increases expression

Clotrimazole results in increased expression of ITGB1 mRNA

NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195

G

inter-alpha trypsin inhibitor, heavy chain 3

increases expression

Clotrimazole results in increased expression of ITIH3 mRNA

NCBI chr16:6,101,922...6,117,154
Ensembl chr16:6,101,930...6,116,924

G

potassium voltage-gated channel subfamily H member 2

decreases activity

Clotrimazole results in decreased activity of KCNH2 protein

NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008

G

potassium inwardly-rectifying channel, subfamily J, member 1

decreases expression

Clotrimazole results in decreased expression of KCNJ1 mRNA

NCBI chr 8:30,779,883...30,808,607
Ensembl chr 8:30,753,617...30,813,796

G

potassium calcium-activated channel subfamily N member 4

multiple interactions
decreases activity

Clotrimazole inhibits the reaction [[Ionomycin co-treated with Tetraethylammonium] results in increased activity of KCNN4 protein]
[S-allylcysteine co-treated with Clotrimazole] inhibits the reaction [lead acetate results in increased activity of KCNN4 protein]; Clotrimazole inhibits the reaction [lead acetate results in increased activity of KCNN4 protein]
Clotrimazole results in decreased activity of KCNN4 protein

PMID:14985237 PMID:15921678 PMID:17699636 PMID:20050851 PMID:22033380

NCBI chr 1:79,956,380...79,974,354
Ensembl chr 1:79,959,322...79,974,340

G

lysine demethylase 4A

decreases expression

Clotrimazole results in decreased expression of KDM4A mRNA

NCBI chr 5:131,672,754...131,719,534
Ensembl chr 5:131,672,754...131,719,501

G

lecithin cholesterol acyltransferase

decreases expression

Clotrimazole results in decreased expression of LCAT mRNA

NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231

G

LHFPL tetraspan subfamily member 5

decreases expression

Clotrimazole results in decreased expression of LHFPL5 mRNA

NCBI chr20:6,632,324...6,642,534
Ensembl chr20:6,632,362...6,642,532

G

LIM zinc finger domain containing 2

decreases expression

Clotrimazole results in decreased expression of LIMS2 mRNA

NCBI chr18:23,553,937...23,592,137
Ensembl chr18:23,553,937...23,592,137

G

lipase G, endothelial type

decreases expression

Clotrimazole results in decreased expression of LIPG mRNA

NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260

G

lysyl oxidase-like 1

increases expression

Clotrimazole results in increased expression of LOXL1 mRNA

NCBI chr 8:58,691,763...58,716,365
Ensembl chr 8:58,692,593...58,716,356

G

LDL receptor related protein 1

decreases expression

Clotrimazole results in decreased expression of LRP1 mRNA

NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910

G

limbic system-associated membrane protein

decreases expression

Clotrimazole results in decreased expression of LSAMP mRNA

NCBI chr11:58,547,533...60,717,328
Ensembl chr11:58,554,805...60,717,029

G

latent transforming growth factor beta binding protein 4

decreases expression

Clotrimazole results in decreased expression of LTBP4 mRNA

NCBI chr 1:82,600,136...82,634,346
Ensembl chr 1:82,600,136...82,632,178

G

mitogen activated protein kinase 14

multiple interactions

MAPK14 promotes the reaction [Clotrimazole results in increased expression of ABCC3 mRNA]

NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589

G

microtubule-associated protein tau

decreases expression

Clotrimazole results in decreased expression of MAPT mRNA

NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129

G

myristoylated alanine rich protein kinase C substrate

increases expression

Clotrimazole results in increased expression of MARCKS mRNA

NCBI chr20:40,685,315...40,691,012
Ensembl chr20:40,685,315...40,691,012

G

microtubule affinity regulating kinase 3

increases expression

Clotrimazole results in increased expression of MARK3 mRNA

NCBI chr 6:130,626,612...130,716,245
Ensembl chr 6:130,627,482...130,716,647

G

muscleblind-like splicing regulator 1

decreases expression

Clotrimazole results in decreased expression of MBNL1 mRNA

NCBI chr 2:144,639,819...144,814,395
Ensembl chr 2:144,670,285...144,814,368

G

multiple coagulation factor deficiency 2, ER cargo receptor complex subunit

increases expression

Clotrimazole results in increased expression of MCFD2 mRNA

NCBI chr 6:7,274,469...7,285,841
Ensembl chr 6:7,274,469...7,285,841

G

microfibril associated protein 2

decreases expression

Clotrimazole results in decreased expression of MFAP2 mRNA

NCBI chr 5:153,312,068...153,320,266
Ensembl chr 5:153,314,711...153,320,259

G

mirror-image polydactyly 1

decreases expression

Clotrimazole results in decreased expression of MIPOL1 mRNA

NCBI chr 6:74,755,293...75,090,403
Ensembl chr 6:74,755,395...75,086,811

G

microRNA 96

increases expression

Clotrimazole results in increased expression of MIR96 mRNA

NCBI chr 4:58,788,411...58,788,516
Ensembl chr 4:58,788,411...58,788,516

G

MLLT3, super elongation complex subunit

increases expression

Clotrimazole results in increased expression of MLLT3 mRNA

NCBI chr 5:102,259,075...102,515,447
Ensembl chr 5:102,260,011...102,515,361

G

maturin, neural progenitor differentiation regulator homolog

decreases expression

Clotrimazole results in decreased expression of MTURN mRNA

NCBI chr 4:83,807,528...83,828,494
Ensembl chr 4:83,807,579...83,824,950

G

matrix remodeling associated 8

decreases expression

Clotrimazole results in decreased expression of MXRA8 mRNA

NCBI chr 5:166,448,919...166,453,645
Ensembl chr 5:166,449,154...166,453,636

G

MYC proto-oncogene, bHLH transcription factor

decreases expression

Clotrimazole results in decreased expression of MYC protein

NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630

G

myc target 1

increases expression

Clotrimazole results in increased expression of MYCT1 mRNA

NCBI chr 1:42,018,137...42,029,410
Ensembl chr 1:42,018,137...42,029,410

G

myelin expression factor 2

increases expression

Clotrimazole results in increased expression of MYEF2 mRNA

NCBI chr 3:112,338,241...112,374,122
Ensembl chr 3:112,338,241...112,374,181

G

myosin light chain 9

increases expression

Clotrimazole results in increased expression of MYL9 mRNA

NCBI chr 3:145,281,943...145,288,333
Ensembl chr 3:145,281,937...145,288,333

G

myosin XVI

increases expression

Clotrimazole results in increased expression of MYO16 mRNA

NCBI chr16:78,884,405...79,364,445
Ensembl chr16:78,884,406...79,248,388

G

myosin Ib

increases expression

Clotrimazole results in increased expression of MYO1B mRNA

NCBI chr 9:49,690,043...49,852,373
Ensembl chr 9:49,690,086...49,850,798

G

N-acetylated alpha-linked acidic dipeptidase-like 2

decreases expression

Clotrimazole results in decreased expression of NAALADL2 mRNA

NCBI chr 2:106,639,146...107,992,218
Ensembl chr 2:106,645,608...107,991,689

G

NACC family member 2

decreases expression

Clotrimazole results in decreased expression of NACC2 mRNA

NCBI chr 3:8,879,952...8,946,660
Ensembl chr 3:8,883,065...8,946,660

G

nuclear receptor coactivator 1

multiple interactions

Clotrimazole promotes the reaction [NR1I3 protein modified form binds to NCOA1 protein]
Clotrimazole promotes the reaction [NR1I2 protein binds to NCOA1 protein]; Clotrimazole promotes the reaction [NR1I3 protein modified form binds to NCOA1 protein]

PMID:17998298 PMID:18973326 PMID:21924250

NCBI chr 6:27,232,609...27,507,992
Ensembl chr 6:27,232,611...27,475,664

G

nuclear receptor co-repressor 1

multiple interactions

Clotrimazole promotes the reaction [NR1I3 protein modified form binds to NCOR1 protein]

NCBI chr10:46,999,536...47,142,294
Ensembl chr10:46,999,536...47,141,032

G

Nedd4 family interacting protein 2

increases expression

Clotrimazole results in increased expression of NDFIP2 mRNA

NCBI chr15:82,032,366...82,087,043
Ensembl chr15:82,032,366...82,086,317

G

NADH:ubiquinone oxidoreductase subunit A5

increases expression

Clotrimazole results in increased expression of NDUFA5 mRNA

NCBI chr 4:52,997,327...53,005,685
Ensembl chr 4:52,995,546...53,005,598
Ensembl chr 5:52,995,546...53,005,598

G

NADH:ubiquinone oxidoreductase complex assembly factor 7

increases expression

Clotrimazole results in increased expression of NDUFAF7 mRNA

NCBI chr 6:16,108,630...16,119,810
Ensembl chr 6:16,103,003...16,119,810

G

NADH:ubiquinone oxidoreductase subunit B5

increases expression

Clotrimazole results in increased expression of NDUFB5 mRNA

NCBI chr 2:115,519,248...115,533,589
Ensembl chr 2:115,519,154...115,533,589

G

NADH:ubiquinone oxidoreductase core subunit S3

increases expression

Clotrimazole results in increased expression of NDUFS3 mRNA

NCBI chr 3:76,876,646...76,883,824
Ensembl chr 3:76,876,646...76,883,824

G

NADH:ubiquinone oxidoreductase subunit S6

increases expression

Clotrimazole results in increased expression of NDUFS6 mRNA

NCBI chr 1:29,968,833...29,977,423
Ensembl chr 1:29,968,842...29,977,467

G

NEDD4 E3 ubiquitin protein ligase

decreases expression

Clotrimazole results in decreased expression of NEDD4 mRNA

NCBI chr 8:73,384,095...73,468,951
Ensembl chr 8:73,383,695...73,468,951

G

niban apoptosis regulator 1

increases expression

Clotrimazole results in increased expression of FAM129A mRNA

NCBI chr13:63,674,240...63,827,748
Ensembl chr13:63,674,171...63,827,729

G

nidogen 1

increases expression

Clotrimazole results in increased expression of NID1 mRNA

NCBI chr17:86,085,133...86,158,272
Ensembl chr17:86,085,077...86,158,267

G

nipsnap homolog 1

decreases expression

Clotrimazole results in decreased expression of NIPSNAP1 mRNA

NCBI chr14:79,734,234...79,758,101
Ensembl chr14:79,734,209...79,758,098

G

nipsnap homolog 3A (C. elegans)

increases expression

Clotrimazole results in increased expression of NIPSNAP3B mRNA

NCBI chr 5:67,613,993...67,625,067
Ensembl chr 5:67,614,036...67,669,700

G

NIN1 (RPN12) binding protein 1 homolog

decreases expression

Clotrimazole results in decreased expression of NOB1 mRNA

NCBI chr19:35,322,803...35,335,354
Ensembl chr19:35,322,669...35,346,815

G

nuclear receptor subfamily 1, group I, member 2

multiple interactions
increases activity
increases expression

Clotrimazole binds to and results in increased activity of NR1I2 protein; Clotrimazole promotes the reaction [NR1I2 protein binds to NCOA1 protein]; Clotrimazole promotes the reaction [NR1I2 results in increased expression of CYP3A4 mRNA]; Dexamethasone promotes the reaction [NR3C1 protein affects the reaction [NR1I2 protein promotes the reaction [Clotrimazole results in increased expression of CYP2B6 mRNA]]]; NR1I2 protein affects the reaction [Clotrimazole results in increased expression of and results in increased activity of CYP2B6 protein]; NR1I2 protein promotes the reaction [Clotrimazole results in increased expression of CYP2B6 mRNA]; NR1I2 protein promotes the reaction [Clotrimazole results in increased expression of CYP3A4 mRNA]
Clotrimazole results in increased activity of NR1I2 protein
Clotrimazole results in increased expression of NR1I2 mRNA

PMID:12049174 PMID:12065438 PMID:12695351 PMID:14977870 PMID:15548381 More...

NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658

G

nuclear receptor subfamily 1, group I, member 3

multiple interactions
decreases activity
increases activity
affects binding

1,1-bis(4-hydroxyphenyl)cyclohexane inhibits the reaction [Clotrimazole binds to NR1I3 protein]; 4,4'-hexafluorisopropylidene diphenol inhibits the reaction [Clotrimazole binds to NR1I3 protein]; androstan-3-ol inhibits the reaction [Clotrimazole binds to NR1I3 protein]; bisphenol A inhibits the reaction [Clotrimazole binds to NR1I3 protein]; bisphenol B inhibits the reaction [Clotrimazole binds to NR1I3 protein]; Clotrimazole binds to and affects the activity of NR1I3 protein; Clotrimazole binds to and results in decreased activity of NR1I3 protein; Clotrimazole binds to and results in increased activity of and results in increased localization of NR1I3 protein mutant form; Clotrimazole binds to and results in increased activity of NR1I3 protein alternative form; Clotrimazole inhibits the reaction [4-nonylphenol results in increased activity of NR1I3 protein]; Clotrimazole inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime binds to and results in increased activity of NR1I3 protein mutant form]; Clotrimazole promotes the reaction [NR1I3 protein modified form binds to NCOA1 protein]
Clotrimazole results in decreased activity of NR1I3 protein
Clotrimazole results in increased activity of NR1I3 protein; Clotrimazole results in increased activity of NR1I3 protein alternative form
Clotrimazole results in decreased activity of NR1I3 protein; Clotrimazole results in decreased activity of NR1I3 protein alternative form
Clotrimazole results in increased activity of NR1I3 protein; Clotrimazole results in increased activity of NR1I3 protein alternative form; Clotrimazole results in increased activity of NR1I3 protein mutant form
androstan-3-ol inhibits the reaction [Clotrimazole results in increased activity of NR1I3 protein mutant form]; Clotrimazole inhibits the reaction [androstan-3-ol results in decreased activity of NR1I3 protein alternative form]; Clotrimazole inhibits the reaction [Imidazoles results in decreased activity of NR1I3 protein alternative form]; Imidazoles inhibits the reaction [Clotrimazole results in increased activity of NR1I3 protein mutant form]
Clotrimazole results in increased activity of NR1I3 protein; Clotrimazole results in increased activity of NR1I3 protein mutant form
Clotrimazole promotes the reaction [NR1I3 protein modified form binds to NCOA1 protein]; Clotrimazole promotes the reaction [NR1I3 protein modified form binds to NCOR1 protein]; NR1I3 protein affects the reaction [Clotrimazole results in increased expression of CYP2B10 mRNA]

PMID:12049174 PMID:15905360 PMID:16919048 PMID:18973326 PMID:20686338 More...

NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906

G

nuclear receptor subfamily 3, group C, member 1

multiple interactions

Dexamethasone promotes the reaction [NR3C1 protein affects the reaction [NR1I2 protein promotes the reaction [Clotrimazole results in increased expression of CYP2B6 mRNA]]]

NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375

G

neuronal cell adhesion molecule

decreases expression

Clotrimazole results in decreased expression of NRCAM mRNA

NCBI chr 6:61,402,813...61,698,536
Ensembl chr 6:61,329,863...61,702,992

G

NSFL1 cofactor

increases expression

Clotrimazole results in increased expression of NSFL1C mRNA

NCBI chr 3:139,978,306...140,002,876
Ensembl chr 3:139,978,301...140,002,870

G

NudC domain containing 2

increases expression

Clotrimazole results in increased expression of NUDCD2 mRNA

NCBI chr10:25,163,247...25,168,738
Ensembl chr10:25,163,220...25,168,738

G

nudix hydrolase 12

decreases expression

Clotrimazole results in decreased expression of NUDT12 mRNA

NCBI chr 9:98,741,627...98,755,039
Ensembl chr 9:98,742,360...98,755,039

G

ornithine decarboxylase 1

increases expression

Clotrimazole results in increased expression of ODC1 mRNA

NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440

G

optineurin

increases expression

Clotrimazole results in increased expression of OPTN mRNA

NCBI chr17:73,209,572...73,260,251
Ensembl chr17:73,209,575...73,260,251

G

origin recognition complex, subunit 1

increases expression

Clotrimazole results in increased expression of ORC1 mRNA

NCBI chr 5:123,324,273...123,348,375
Ensembl chr 5:123,324,315...123,348,375

G

purinergic receptor P2X 3

decreases expression

Clotrimazole results in decreased expression of P2RX3 mRNA

NCBI chr 3:70,080,850...70,124,664
Ensembl chr 3:70,080,851...70,125,178

G

pecanex 4

decreases expression

Clotrimazole results in decreased expression of PCNXL4 mRNA

NCBI chr 6:91,125,063...91,170,423
Ensembl chr 6:91,125,063...91,170,439

G

platelet derived growth factor receptor beta

increases expression

Clotrimazole results in increased expression of PDGFRB mRNA

NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843

G

pyruvate dehydrogenase complex, component X

increases expression

Clotrimazole results in increased expression of PDHX mRNA

NCBI chr 3:89,372,248...89,431,779
Ensembl chr 3:89,371,497...89,431,773

G

protein disulfide isomerase family A, member 4

increases expression

Clotrimazole results in increased expression of PDIA4 mRNA

NCBI chr 4:76,803,198...76,822,245
Ensembl chr 4:76,803,198...76,822,107

G

peroxisomal biogenesis factor 2

increases expression

Clotrimazole results in increased expression of PEX2 mRNA

NCBI chr 2:96,050,380...96,072,928
Ensembl chr 2:96,045,958...96,073,404

G

phosphofructokinase, muscle

decreases expression

Clotrimazole results in decreased expression of PFKM mRNA

NCBI chr 7:129,221,679...129,259,192
Ensembl chr 7:129,221,653...129,259,192

G

phosphofructokinase, platelet

affects localization

Clotrimazole affects the localization of PFKP protein

NCBI chr17:63,729,743...63,794,026
Ensembl chr17:63,729,780...63,794,018

G

PHD finger protein 1

decreases expression

Clotrimazole results in decreased expression of PHF1 mRNA

NCBI chr20:5,017,765...5,022,872
Ensembl chr20:5,017,893...5,022,871

G

protein inhibitor of activated STAT, 1

decreases expression

Clotrimazole results in decreased expression of PIAS1 mRNA

NCBI chr 8:63,338,150...63,451,670
Ensembl chr 8:63,338,150...63,438,905

G

PTEN induced kinase 1

decreases expression

Clotrimazole results in decreased expression of PINK1 mRNA

NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635

G

phospholipase A1 member A

increases expression

Clotrimazole results in increased expression of PLA1A mRNA

NCBI chr11:62,320,112...62,357,779
Ensembl chr11:62,320,493...62,357,779

G

plasminogen activator, urokinase

decreases expression

Clotrimazole results in decreased expression of PLAU mRNA

NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775

G

phospholipase C, eta 2

decreases expression

Clotrimazole results in decreased expression of PLCH2 mRNA

NCBI chr 5:165,544,209...165,613,769
Ensembl chr 5:165,544,200...165,602,356

G

pleckstrin homology domain containing O1

increases expression

Clotrimazole results in increased expression of PLEKHO1 mRNA

NCBI chr 2:183,544,487...183,552,928
Ensembl chr 2:183,544,499...183,552,785

G

podocalyxin-like

increases expression

Clotrimazole results in increased expression of PODXL mRNA

NCBI chr 4:60,135,124...60,181,829
Ensembl chr 4:60,135,109...60,181,899

G

DNA polymerase epsilon 3, accessory subunit

increases expression

Clotrimazole results in increased expression of POLE3 mRNA

NCBI chr 5:75,973,941...75,977,175
Ensembl chr 5:75,974,717...75,977,231
Ensembl chr 7:75,974,717...75,977,231

G

protein phosphatase, Mg2+/Mn2+ dependent, 1J

decreases expression

Clotrimazole results in decreased expression of PPM1J mRNA

NCBI chr 2:192,278,597...192,283,883
Ensembl chr 2:192,278,517...192,283,882

G

protein phosphatase 1, regulatory subunit 9A

decreases expression

Clotrimazole results in decreased expression of PPP1R9A mRNA

NCBI chr 4:32,970,501...33,292,360
Ensembl chr 4:33,024,450...33,286,907

G

peroxiredoxin 2

multiple interactions

[S-allylcysteine co-treated with Clotrimazole] inhibits the reaction [lead acetate affects the localization of PRDX2 protein]; [S-allylcysteine co-treated with Clotrimazole] inhibits the reaction [lead acetate promotes the reaction [PRDX2 protein binds to PRDX2 protein]]; Clotrimazole inhibits the reaction [lead acetate promotes the reaction [PRDX2 protein binds to PRDX2 protein]]

NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194

G

protein kinase C, eta

increases expression

Clotrimazole results in increased expression of PRKCH mRNA

NCBI chr 6:92,292,000...92,490,663
Ensembl chr 6:92,292,000...92,490,654

G

protein kinase D2

decreases expression

Clotrimazole results in decreased expression of PRKD2 mRNA

NCBI chr 1:77,513,625...77,542,386
Ensembl chr 1:77,513,986...77,542,376

G

paired related homeobox 1

increases expression

Clotrimazole results in increased expression of PRRX1 mRNA

NCBI chr13:75,600,777...75,671,896
Ensembl chr13:75,601,706...75,670,866

G

serine protease 41

decreases expression

Clotrimazole results in decreased expression of PRSS41 mRNA

NCBI chr10:12,865,872...12,873,552
Ensembl chr10:12,865,872...12,873,552

G

PC4 and SRSF1 interacting protein 1

increases expression

Clotrimazole results in increased expression of PSIP1 mRNA

NCBI chr 5:97,847,010...97,879,280
Ensembl chr 5:97,847,015...97,879,257

G

prostaglandin F2 receptor inhibitor

increases expression

Clotrimazole results in increased expression of PTGFRN mRNA

NCBI chr 2:188,469,521...188,544,795
Ensembl chr 2:188,469,521...188,544,795

G

RAB11 family interacting protein 4

increases expression

Clotrimazole results in increased expression of RAB11FIP4 mRNA

NCBI chr10:64,550,109...64,658,123
Ensembl chr10:64,550,177...64,654,759

G

RAB9A, member RAS oncogene family

decreases expression

Clotrimazole results in decreased expression of RAB9A mRNA

NCBI chr X:27,955,552...28,009,870
Ensembl chr X:27,952,204...28,001,622

G

RAD18 E3 ubiquitin protein ligase

increases expression

Clotrimazole results in increased expression of RAD18 mRNA

NCBI chr 4:145,735,654...145,821,102
Ensembl chr 4:145,735,654...145,821,069

G

ralA binding protein 1

decreases expression

Clotrimazole results in decreased expression of RALBP1 mRNA

NCBI chr 9:105,456,425...105,493,235
Ensembl chr 9:105,456,425...105,492,707

G

Ras interacting protein 1

increases expression

Clotrimazole results in increased expression of RASIP1 mRNA

NCBI chr 1:96,097,135...96,109,564
Ensembl chr 1:96,091,074...96,109,562

G

retinol binding protein 2

increases expression

Clotrimazole results in increased expression of RBP2 mRNA

NCBI chr 8:99,079,293...99,104,489
Ensembl chr 8:99,079,104...99,104,473

G

replication factor C subunit 2

increases expression

Clotrimazole results in increased expression of RFC2 mRNA

NCBI chr12:22,120,449...22,133,576
Ensembl chr12:22,120,010...22,133,557

G

raftlin family member 2

decreases expression

Clotrimazole results in decreased expression of RFTN2 mRNA

NCBI chr 9:56,651,617...56,707,830
Ensembl chr 9:56,630,460...56,707,810

G

regucalcin

decreases expression

Clotrimazole results in decreased expression of RGN mRNA

NCBI chr X:1,619,030...1,634,456
Ensembl chr X:1,619,032...1,634,450

G

regulator of G-protein signaling 5

increases expression

Clotrimazole results in increased expression of RGS5 mRNA

NCBI chr13:81,848,254...81,885,053
Ensembl chr13:81,836,304...81,885,518

G

regulator of G protein signaling 9 binding protein

decreases expression

Clotrimazole results in decreased expression of RGS9BP mRNA

NCBI chr 1:88,249,438...88,250,151
Ensembl chr 1:88,249,438...88,250,151

G

Rab interacting lysosomal protein-like 1

decreases expression

Clotrimazole results in decreased expression of RILPL1 mRNA

NCBI chr12:32,071,870...32,109,687
Ensembl chr12:32,071,693...32,109,938

G

ring finger protein 8

decreases expression

Clotrimazole results in decreased expression of RNF8 mRNA

NCBI chr20:7,682,258...7,710,448
Ensembl chr20:7,682,322...7,708,491

G

ribosomal protein S27-like

increases expression

Clotrimazole results in increased expression of RPS27L mRNA

NCBI chr 8:67,562,483...67,567,418
Ensembl chr 8:67,562,483...67,567,418
Ensembl chr12:67,562,483...67,567,418
Ensembl chr 2:67,562,483...67,567,418

G

ribosomal protein S6 kinase B2

decreases expression

Clotrimazole results in decreased expression of RPS6KB2 mRNA

NCBI chr 1:201,451,265...201,458,096
Ensembl chr 1:201,451,265...201,458,078

G

round spermatid basic protein 1

decreases expression

Clotrimazole results in decreased expression of RSBN1 mRNA

NCBI chr 2:191,416,631...191,470,711
Ensembl chr 2:191,416,631...191,470,711

G

schwannomin interacting protein 1

increases expression

Clotrimazole results in increased expression of SCHIP1 mRNA

NCBI chr 2:152,127,171...152,888,587
Ensembl chr 2:152,126,953...152,888,585

G

succinate dehydrogenase complex subunit D

increases expression

Clotrimazole results in increased expression of SDHD mRNA

NCBI chr 8:50,944,702...50,954,298
Ensembl chr 8:50,944,704...50,954,238

G

SUMO specific peptidase 7

decreases expression

Clotrimazole results in decreased expression of SENP7 mRNA

NCBI chr11:44,423,733...44,584,129
Ensembl chr11:44,423,735...44,564,711

G

SUMO peptidase family member, NEDD8 specific

decreases expression

Clotrimazole results in decreased expression of SENP8 mRNA

NCBI chr 8:60,135,446...60,148,836
Ensembl chr 8:60,121,714...60,148,928

G

serpin family F member 1

decreases expression

Clotrimazole results in decreased expression of SERPINF1 mRNA

NCBI chr10:60,250,198...60,262,593
Ensembl chr10:60,249,708...60,262,646

G

serum/glucocorticoid regulated kinase 1

increases expression

Clotrimazole results in increased expression of SGK1 mRNA

NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283

G

sialic acid binding Ig like lectin 1

decreases expression

Clotrimazole results in decreased expression of SIGLEC1 mRNA

NCBI chr 3:118,287,988...118,307,125
Ensembl chr 3:118,287,988...118,306,850

G

signal-induced proliferation-associated 1

increases expression

Clotrimazole results in increased expression of SIPA1 mRNA

NCBI chr 1:202,938,532...202,950,672
Ensembl chr 1:202,938,580...202,950,591

G

solute carrier family 19 member 1

multiple interactions
decreases activity

Clotrimazole inhibits the reaction [SLC19A1 protein results in increased uptake of Methotrexate]
Clotrimazole results in decreased activity of SLC19A1 protein

NCBI chr20:11,584,410...11,602,429
Ensembl chr20:11,584,411...11,601,972

G

solute carrier family 25 member 14

decreases expression

Clotrimazole results in decreased expression of SLC25A14 mRNA

NCBI chr X:127,807,630...127,845,823
Ensembl chr X:127,807,449...127,845,823

G

sphingomyelin phosphodiesterase 1

multiple interactions

[S-allylcysteine co-treated with Clotrimazole] inhibits the reaction [lead acetate results in increased activity of SMPD1 protein]; Clotrimazole inhibits the reaction [lead acetate results in increased activity of SMPD1 protein]

NCBI chr 1:159,892,946...159,896,789
Ensembl chr 1:159,892,859...159,896,794

G

small nuclear ribonucleoprotein U4/U6.U5 subunit 27

increases expression

Clotrimazole results in increased expression of SNRNP27 mRNA

NCBI chr 4:119,123,676...119,133,234
Ensembl chr 4:119,121,877...119,133,234

G

sorting nexin 16

decreases expression

Clotrimazole results in decreased expression of SNX16 mRNA

NCBI chr 2:91,335,896...91,357,622
Ensembl chr 2:91,336,092...91,357,619

G

sorting nexin 24

decreases expression

Clotrimazole results in decreased expression of SNX24 mRNA

NCBI chr18:46,670,987...46,826,070
Ensembl chr18:46,671,443...46,826,068

G

sorting nexin 33

decreases expression

Clotrimazole results in decreased expression of SNX33 mRNA

NCBI chr 8:57,315,861...57,328,522
Ensembl chr 8:57,317,161...57,327,538

G

sorbitol dehydrogenase

increases expression

Clotrimazole results in increased expression of SORD mRNA

NCBI chr 3:109,184,697...109,216,133
Ensembl chr 3:109,184,676...109,216,133

G

serine palmitoyltransferase, small subunit A

increases expression

Clotrimazole results in increased expression of SPTSSA mRNA

NCBI chr 6:72,144,714...72,156,130
Ensembl chr 6:72,144,714...72,156,214

G

signal recognition particle 9

increases expression

Clotrimazole results in increased expression of SRP9 mRNA

NCBI chr13:93,832,580...93,840,720
Ensembl chr13:93,832,580...93,840,720

G

sushi-repeat-containing protein, X-linked

decreases expression

Clotrimazole results in decreased expression of SRPX mRNA

NCBI chr X:12,676,984...12,751,296
Ensembl chr X:12,566,645...12,747,882

G

sushi-repeat-containing protein, X-linked 2

increases expression

Clotrimazole results in increased expression of SRPX2 mRNA

NCBI chr X:97,106,455...97,132,197
Ensembl chr X:97,106,561...97,132,195

G

sarcospan

decreases expression

Clotrimazole results in decreased expression of SSPN mRNA

NCBI chr 4:178,890,030...178,946,267
Ensembl chr 4:178,897,147...178,931,554

G

SH3 and cysteine rich domain

increases expression

Clotrimazole results in increased expression of STAC mRNA

NCBI chr 8:111,530,800...111,653,228
Ensembl chr 8:111,530,800...111,654,008

G

stonin 1

decreases expression

Clotrimazole results in decreased expression of RAET1L mRNA

NCBI chr 6:5,843,186...5,892,557
Ensembl chr 6:5,843,185...5,892,449

G

serine/threonine/tyrosine interacting-like 1

decreases expression

Clotrimazole results in decreased expression of STYXL1 mRNA

NCBI chr12:20,907,410...20,940,232
Ensembl chr12:20,907,435...20,939,752

G

sulfotransferase family 1A member 1

decreases expression

Clotrimazole results in decreased expression of SULT1A1 mRNA

NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562

G

sulfotransferase family 2A member 1

decreases expression

Clotrimazole results in decreased expression of SULT2A1 mRNA

NCBI chr 1:75,451,178...75,508,113
Ensembl chr 1:74,911,100...75,508,134

G

SURF1, cytochrome c oxidase assembly factor

decreases expression

Clotrimazole results in decreased expression of SURF1 mRNA

NCBI chr 3:10,241,793...10,244,686
Ensembl chr 3:10,241,837...10,263,315

G

spectrin repeat containing nuclear envelope protein 2

decreases expression

Clotrimazole results in decreased expression of SYNE2 mRNA

NCBI chr 6:94,537,088...94,848,085
Ensembl chr 6:94,537,088...94,848,064

G

tafazzin, phospholipid-lysophospholipid transacylase

increases expression

Clotrimazole results in increased expression of TAZ mRNA

NCBI chr X:152,065,539...152,076,178
Ensembl chr X:152,065,609...152,074,001

G

transgelin

increases expression

Clotrimazole results in increased expression of TAGLN mRNA

NCBI chr 8:46,224,939...46,230,413
Ensembl chr 8:46,222,472...46,230,668

G

tet methylcytosine dioxygenase 3

decreases expression

Clotrimazole results in decreased expression of TET3 mRNA

NCBI chr 4:115,867,412...115,964,433
Ensembl chr 4:115,871,265...115,964,193

G

transforming growth factor, beta 1

increases expression

Clotrimazole results in increased expression of TGFB1 mRNA

NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847

G

transforming growth factor, beta induced

decreases expression

Clotrimazole results in decreased expression of TGFBI mRNA

NCBI chr17:7,955,603...7,984,903
Ensembl chr17:7,955,603...7,985,240

G

THAP domain containing 3

decreases expression

Clotrimazole results in decreased expression of THAP3 mRNA

NCBI chr 5:162,488,480...162,494,149
Ensembl chr 5:162,488,480...162,494,149

G

transmembrane p24 trafficking protein 4

increases expression

Clotrimazole results in increased expression of TMED4 mRNA

NCBI chr14:81,125,049...81,129,646
Ensembl chr14:81,125,053...81,129,631

G

transmembrane p24 trafficking protein 7

increases expression

Clotrimazole results in increased expression of TMED7 mRNA

NCBI chr18:39,318,564...39,325,640
Ensembl chr18:39,297,351...39,325,640

G

transmembrane protein with EGF-like and two follistatin-like domains 2

multiple interactions

[Clotrimazole results in increased phosphorylation of EIF2A protein] which results in increased expression of TMEFF2 protein

NCBI chr 9:50,445,947...50,733,473
Ensembl chr 9:50,436,079...50,733,475

G

transmembrane protein 116

decreases expression

Clotrimazole results in decreased expression of TMEM116 mRNA

NCBI chr12:35,021,912...35,089,409
Ensembl chr12:35,041,572...35,089,430

G

transmembrane protein 39b

decreases expression

Clotrimazole results in decreased expression of TMEM39B mRNA

NCBI chr 5:142,024,271...142,046,607
Ensembl chr 5:142,024,273...142,046,549

G

transmembrane protein 88

increases expression

Clotrimazole results in increased expression of TMEM88 mRNA

NCBI chr10:54,118,752...54,120,447
Ensembl chr10:54,118,752...54,120,447

G

transmembrane protein 97

increases expression

Clotrimazole results in increased expression of TMEM97 mRNA

NCBI chr10:63,438,228...63,447,311
Ensembl chr10:63,438,222...63,589,730

G

transmembrane serine protease 9

decreases expression

Clotrimazole results in decreased expression of TMPRSS9 mRNA

NCBI chr 7:8,810,321...8,831,177
Ensembl chr 7:8,810,320...8,831,177

G

tankyrase 1 binding protein 1

increases expression

Clotrimazole results in increased expression of TNKS1BP1 mRNA

NCBI chr 3:70,135,335...70,160,071
Ensembl chr 3:70,137,837...70,160,038

G

tenascin XA, pseudogene 1

decreases expression

Clotrimazole results in decreased expression of TNXA-PS1 mRNA

NCBI chr20:4,026,471...4,027,826

G

tumor protein p53

increases expression

Clotrimazole results in increased expression of TP53 protein

NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524

G

tropomyosin 2

increases expression

Clotrimazole results in increased expression of TPM2 mRNA

NCBI chr 5:57,770,919...57,780,278
Ensembl chr 5:57,770,864...57,779,992

G

Tnf receptor associated factor 4

increases expression

Clotrimazole results in increased expression of TRAF4 mRNA

NCBI chr10:63,054,169...63,060,284
Ensembl chr10:63,054,181...63,060,284

G

transient receptor potential cation channel, subfamily C, member 6

increases expression

Clotrimazole results in increased expression of TRPC6 mRNA

NCBI chr 8:5,759,387...5,864,000
Ensembl chr 8:5,758,935...5,828,092

G

transient receptor potential cation channel, subfamily M, member 2

multiple interactions

Clotrimazole inhibits the reaction [Adenosine Diphosphate Ribose promotes the reaction [TRPM2 protein results in increased transport of Calcium]]
[Clotrimazole results in decreased activity of TRPM2 protein] inhibits the reaction [Mustard Gas results in increased abundance of Calcium]

PMID:21900507 PMID:22036725

NCBI chr20:10,703,568...10,753,189
Ensembl chr20:10,707,014...10,753,181

G

thiosulfate sulfurtransferase like domain containing 2

decreases expression

Clotrimazole results in decreased expression of TSTD2 mRNA

NCBI chr 5:60,371,751...60,415,916
Ensembl chr 5:60,393,454...60,415,916

G

tetratricopeptide repeat domain 33

decreases expression

Clotrimazole results in decreased expression of TTC33 mRNA

NCBI chr 2:54,279,906...54,326,851
Ensembl chr 2:54,279,997...54,323,871

G

tubulin, beta 2A class IIa

increases expression

Clotrimazole results in increased expression of TUBB2A mRNA

NCBI chr17:30,796,842...30,800,713
Ensembl chr17:30,747,503...30,800,714

G

taxilin alpha

increases expression

Clotrimazole results in increased expression of TXLNA mRNA

NCBI chr 5:141,969,337...141,985,054
Ensembl chr 5:141,969,346...141,984,583

G

U2 snRNP-associated SURP domain containing

decreases expression

Clotrimazole results in decreased expression of U2SURP mRNA

NCBI chr 8:96,018,932...96,075,795
Ensembl chr 8:96,022,957...96,075,691

G

UDP glucuronosyltransferase family 1 member A1

affects expression

Clotrimazole affects the expression of UGT1A1 mRNA

NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465

G

UPF2, regulator of nonsense mediated mRNA decay

decreases expression

Clotrimazole results in decreased expression of UPF2 mRNA

NCBI chr17:72,224,575...72,335,896
Ensembl chr17:72,225,316...72,335,855

G

ubiquinol-cytochrome c reductase, complex III subunit X

increases expression

Clotrimazole results in increased expression of UQCR10 mRNA

NCBI chr14:79,566,151...79,569,017
Ensembl chr14:79,566,157...79,569,003

G

vasohibin 2

increases expression

Clotrimazole results in increased expression of VASH2 mRNA

NCBI chr13:102,529,718...102,561,204
Ensembl chr13:102,529,719...102,560,391

G

vascular endothelial growth factor A

multiple interactions
increases secretion

[Clotrimazole co-treated with Imatinib Mesylate] results in increased secretion of VEGFA protein
Clotrimazole results in increased secretion of VEGFA protein

NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641

G

Wnt family member 2

decreases expression

Clotrimazole results in decreased expression of WNT2 mRNA

NCBI chr 4:46,328,408...46,374,673
Ensembl chr 4:46,333,998...46,374,402

G

exportin 4

decreases expression

Clotrimazole results in decreased expression of XPO4 mRNA

NCBI chr15:31,717,016...31,807,723
Ensembl chr15:31,716,762...31,807,908

G

zinc finger and BTB domain containing 10

decreases expression

Clotrimazole results in decreased expression of ZBTB10 mRNA

NCBI chr 2:92,475,254...92,509,892
Ensembl chr 2:92,479,014...92,512,515

G

zinc finger protein 407

increases expression

Clotrimazole results in increased expression of ZFP407 mRNA

NCBI chr18:77,571,140...77,970,282
Ensembl chr18:77,571,204...77,974,129

G

zinc finger and SCAN domain containing 2

decreases expression

Clotrimazole results in decreased expression of ZSCAN2 mRNA

NCBI chr 1:134,833,701...134,848,957
Ensembl chr 1:134,833,871...134,848,952

cyazofamid

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily B member 1A

increases transport
multiple interactions

ABCB1 protein results in increased transport of cyazofamid
cyazofamid affects the reaction [ABCB1 protein results in increased uptake of Digoxin]; Verapamil inhibits the reaction [ABCB1 protein results in increased transport of cyazofamid]

NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709

G

ATP binding cassette subfamily C member 2

increases uptake

ABCC2 protein results in increased uptake of cyazofamid

NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238

G

ATP binding cassette subfamily G member 2

increases uptake

ABCG2 protein results in increased uptake of cyazofamid

NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409

G

cytochrome P450, family 3, subfamily a, polypeptide 9

decreases expression

cyazofamid results in decreased expression of CYP3A5 mRNA

NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422

G

iodothyronine deiodinase 1

decreases activity

cyazofamid results in decreased activity of DIO1 protein

NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970

G

estrogen related receptor, alpha

increases activity

cyazofamid results in increased activity of ESRRA protein

NCBI chr 1:204,104,100...204,114,182
Ensembl chr 1:204,104,101...204,114,268

G

solute carrier family 22 member 6

multiple interactions

cyazofamid inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid]

NCBI chr 1:205,522,579...205,531,179
Ensembl chr 1:205,522,729...205,531,173

G

solute carrier family 22 member 8

multiple interactions

cyazofamid inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate]

NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450

G

solute carrier organic anion transporter family member 1B2

multiple interactions

cyazofamid inhibits the reaction [SLCO1B3 protein results in increased uptake of estrone sulfate]

NCBI chr 4:174,551,463...174,619,988
Ensembl chr 4:174,551,480...174,619,981

econazole

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

adenylate cyclase 9

increases activity

Econazole results in increased activity of ADCY9 protein

NCBI chr10:11,138,966...11,262,067
Ensembl chr10:11,139,446...11,262,066

G

cytochrome P450, family 3, subfamily a, polypeptide 2

multiple interactions
increases expression
decreases activity

Econazole promotes the reaction [NR1I2 results in increased expression of CYP3A4 mRNA]; Econazole promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]
Econazole results in increased expression of CYP3A4 mRNA
Econazole results in decreased activity of CYP3A4 protein

PMID:15135088 PMID:17998298

NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008

G

cytochrome P450, family 51

decreases response to substance

CYP51A1 gene results in decreased susceptibility to Econazole

NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410
Ensembl chr 6:30,036,865...30,055,410

G

glutathione S-transferase pi 1

multiple interactions

Econazole inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate]

NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226

G

potassium voltage-gated channel subfamily A member 3

multiple interactions
decreases activity

[Econazole results in decreased activity of KCNA3 protein] which results in decreased import of Thallium

NCBI chr 2:194,632,106...194,634,059
Ensembl chr 2:194,632,196...194,650,138

G

potassium voltage-gated channel subfamily H member 2

decreases activity
multiple interactions

Econazole results in decreased activity of KCNH2 protein
[Econazole results in decreased activity of KCNH2 protein] which results in decreased import of Thallium

NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008

G

nuclear receptor coactivator 1

multiple interactions

Econazole promotes the reaction [NR1I2 protein binds to NCOA1 protein]

NCBI chr 6:27,232,609...27,507,992
Ensembl chr 6:27,232,611...27,475,664

G

nuclear receptor subfamily 1, group I, member 2

multiple interactions

Econazole binds to and results in increased activity of NR1I2 protein; Econazole promotes the reaction [NR1I2 protein binds to NCOA1 protein]; Econazole promotes the reaction [NR1I2 results in increased expression of CYP3A4 mRNA]

NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658

G

protein kinase AMP-activated catalytic subunit alpha 1

multiple interactions

[tebuconazole co-treated with Econazole] results in increased phosphorylation of PRKAA1 protein

NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978

G

protein kinase AMP-activated catalytic subunit alpha 2

multiple interactions

[tebuconazole co-treated with Econazole] results in increased phosphorylation of PRKAA2 protein

NCBI chr 5:119,807,992...119,879,987
Ensembl chr 5:119,813,226...119,879,543

G

solute carrier family 22 member 2

multiple interactions

Econazole inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium]

NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268

G

transient receptor potential cation channel, subfamily M, member 2

multiple interactions

[Econazole results in decreased activity of TRPM2 protein] inhibits the reaction [Mustard Gas results in increased abundance of Calcium]

NCBI chr20:10,703,568...10,753,189
Ensembl chr20:10,707,014...10,753,181

G

unc-51 like autophagy activating kinase 1

multiple interactions

[tebuconazole co-treated with Econazole] results in increased phosphorylation of ULK1 protein; dorsomorphin inhibits the reaction [[tebuconazole co-treated with Econazole] results in increased phosphorylation of ULK1 protein]

NCBI chr12:45,851,710...45,877,966
Ensembl chr12:45,851,710...45,877,966

enilconazole

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily B member 11

decreases expression

enilconazole results in decreased expression of ABCB11 mRNA

NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730

G

ATP binding cassette subfamily C member 2

decreases expression

enilconazole results in decreased expression of ABCC2 mRNA

NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238

G

ATP binding cassette subfamily C member 3

decreases expression
multiple interactions
increases expression

enilconazole results in decreased expression of ABCC3 mRNA
[enilconazole co-treated with clothianidin] results in increased expression of ABCC3 mRNA; [thiacloprid co-treated with enilconazole] results in increased expression of ABCC3 mRNA
enilconazole results in increased expression of ABCC3 mRNA

PMID:29451352 PMID:33426623

NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595

G

ATP binding cassette subfamily D member 3

decreases expression

enilconazole results in decreased expression of ABCD3 mRNA

NCBI chr 2:209,852,087...209,905,763
Ensembl chr 2:209,852,087...209,906,020

G

acyl-CoA oxidase 1

decreases expression

enilconazole results in decreased expression of ACOX1 mRNA

NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232

G

adenosine kinase

increases expression

enilconazole results in increased expression of ADK mRNA

NCBI chr15:2,863,241...3,246,453
Ensembl chr15:2,863,244...3,246,510

G

aldehyde dehydrogenase 1 family, member A1

decreases expression
multiple interactions
increases expression

enilconazole results in decreased expression of ALDH1A1 mRNA
[enilconazole co-treated with clothianidin] results in increased expression of ALDH1A1 mRNA; [thiacloprid co-treated with enilconazole] results in increased expression of ALDH1A1 mRNA
enilconazole results in increased expression of ALDH1A1 mRNA
[thiacloprid co-treated with enilconazole] results in decreased expression of ALDH1A1 mRNA

PMID:32201337 PMID:33426623

NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961

G

aldehyde dehydrogenase 2 family member

decreases expression
multiple interactions

enilconazole results in decreased expression of ALDH2 mRNA
[Maneb co-treated with mancozeb co-treated with iprodione co-treated with enilconazole co-treated with Chlorpyrifos co-treated with Diazinon co-treated with Dimethoate] results in decreased expression of ALDH2 mRNA; [Maneb co-treated with mancozeb co-treated with iprodione co-treated with enilconazole co-treated with Chlorpyrifos co-treated with Diazinon co-treated with Dimethoate] results in decreased expression of and results in decreased activity of ALDH2 protein

PMID:32201337 PMID:34830855

NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521

G

anoctamin 1

decreases expression

enilconazole results in decreased expression of ANO1 mRNA

NCBI chr 1:199,751,439...199,900,099
Ensembl chr 1:199,751,439...199,900,069

G

annexin A10

increases expression

enilconazole results in increased expression of ANXA10 mRNA

NCBI chr16:27,738,712...27,805,648
Ensembl chr16:27,738,712...27,805,648

G

androgen receptor

multiple interactions
decreases expression
affects binding

Dihydrotestosterone inhibits the reaction [enilconazole results in increased activity of AR protein]; enilconazole inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; enilconazole inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA]; enilconazole inhibits the reaction [Metribolone results in increased activity of AR protein]
enilconazole results in decreased expression of AR mRNA
enilconazole binds to AR protein

PMID:15064155 PMID:18324785 PMID:21310686 PMID:30853599 PMID:33049310

NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925

G

arginase 1

decreases expression

enilconazole results in decreased expression of ARG1 mRNA

NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422

G

ATPase phospholipid transporting 8B1

increases expression

enilconazole results in increased expression of ATP8B1 mRNA

NCBI chr18:58,016,382...58,157,213
Ensembl chr18:58,018,268...58,157,396

G

catalase

increases expression

enilconazole results in increased expression of CAT mRNA

NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478

G

C-C motif chemokine ligand 5

increases expression

enilconazole results in increased expression of CCL5 mRNA

NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377

G

carboxylesterase 2H

multiple interactions
decreases expression

[enilconazole co-treated with thiacloprid] results in increased expression of CES2 protein
enilconazole results in decreased expression of CES2 mRNA

NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830

G

CF transmembrane conductance regulator

affects binding
decreases expression

enilconazole binds to CFTR protein
enilconazole results in decreased expression of CFTR mRNA; enilconazole results in decreased expression of CFTR protein

PMID:29106682 PMID:32814239

NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756

G

catechol-O-methyltransferase

increases expression

enilconazole results in increased expression of COMT protein

NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642

G

cytochrome P450, family 11, subfamily a, polypeptide 1

affects expression

enilconazole affects the expression of CYP11A1 mRNA

NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338

G

cytochrome P450, family 17, subfamily a, polypeptide 1

increases expression

enilconazole results in increased expression of CYP17A1 mRNA

NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573

G

cytochrome P450, family 19, subfamily a, polypeptide 1

decreases activity
affects secretion

enilconazole results in decreased activity of CYP19A1 protein
enilconazole affects the secretion of CYP19A1 mRNA

PMID:10806373 PMID:15554355 PMID:26141389 PMID:30853599

NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758

G

cytochrome P450, family 1, subfamily a, polypeptide 1

increases activity
increases expression
multiple interactions

enilconazole results in increased activity of CYP1A1 protein
enilconazole results in increased expression of CYP1A1 mRNA; enilconazole results in increased expression of CYP1A1 protein
enilconazole inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]

PMID:19070657 PMID:21762035 PMID:32194361

NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125

G

cytochrome P450, family 1, subfamily a, polypeptide 2

affects expression
multiple interactions

enilconazole affects the expression of CYP1A2 mRNA
[clothianidin co-treated with enilconazole] results in increased expression of CYP1A2 mRNA; [enilconazole co-treated with thiacloprid co-treated with clothianidin] results in increased expression of CYP1A2 mRNA; [thiacloprid co-treated with enilconazole] results in increased expression of CYP1A2 mRNA

NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312

G

cytochrome P450, family 1, subfamily b, polypeptide 1

increases expression
multiple interactions

enilconazole results in increased expression of CYP1B1 mRNA
[clothianidin co-treated with enilconazole] results in increased expression of CYP1B1 protein

NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917

G

cytochrome P450, family 27, subfamily a, polypeptide 1

increases expression

enilconazole results in increased expression of CYP27A1 mRNA

NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551

G

cytochrome P450, family 2, subfamily b, polypeptide 2

increases expression
multiple interactions

enilconazole results in increased expression of CYP2B2 mRNA
[enilconazole co-treated with clothianidin] results in increased expression of CYP2B2 mRNA; [thiacloprid co-treated with enilconazole] results in increased expression of CYP2B2 mRNA

NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566

G

cytochrome P450, family 2, subfamily b, polypeptide 3

multiple interactions
increases expression
affects expression

[enilconazole co-treated with thiacloprid] results in increased expression of CYP2B6 protein; [enilconazole co-treated with thiacloprid] results in increased expression of CYP2B9 protein; [thiacloprid co-treated with enilconazole] results in increased expression of CYP2B6 mRNA
enilconazole results in increased expression of CYP2B10
enilconazole affects the expression of CYP2B6 mRNA

PMID:27853109 PMID:32201337

NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143

G

cytochrome P450, family 2, subfamily C, polypeptide 6

decreases expression

enilconazole results in decreased expression of CYP2C19 mRNA; enilconazole results in decreased expression of CYP2C19 protein

PMID:32194361 PMID:32201337

NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596

G

cytochrome P450, family 2, subfamily e, polypeptide 1

multiple interactions
decreases expression

[clothianidin co-treated with enilconazole] results in decreased expression of CYP2E1 mRNA; [enilconazole co-treated with thiacloprid co-treated with clothianidin] results in decreased expression of CYP2E1 mRNA; [thiacloprid co-treated with enilconazole] results in decreased expression of CYP2E1 mRNA
enilconazole results in decreased expression of CYP2E1 mRNA

NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023

G

cytochrome P450, family 3, subfamily a, polypeptide 2

affects expression
decreases activity
multiple interactions
increases expression

enilconazole affects the expression of CYP3A4 mRNA
enilconazole results in decreased activity of CYP3A4 protein
[Amiodarone co-treated with Benzoic Acid co-treated with cyproconazole co-treated with flusilazole co-treated with enilconazole co-treated with prochloraz co-treated with propiconazole co-treated with tebuconazole] results in increased expression of CYP3A4 protein; [clothianidin co-treated with enilconazole] results in increased expression of CYP3A4 mRNA; [clothianidin co-treated with enilconazole] results in increased expression of CYP3A4 protein; [enilconazole co-treated with methidathion] results in increased expression of CYP3A4 mRNA; [enilconazole co-treated with thiacloprid co-treated with clothianidin] results in increased expression of CYP3A4 mRNA; [enilconazole co-treated with thiacloprid] results in increased expression of CYP3A4 protein; [thiacloprid co-treated with enilconazole] results in increased expression of CYP3A4 mRNA
enilconazole results in increased expression of CYP3A4 protein

PMID:21762035 PMID:25028461 PMID:32201337 PMID:34273450

NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008

G

cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1

multiple interactions
increases expression

[enilconazole co-treated with clothianidin] results in increased expression of CYP3A23-3A1 mRNA; [thiacloprid co-treated with enilconazole] results in increased expression of CYP3A23-3A1 mRNA
enilconazole results in increased expression of CYP3A23-3A1 mRNA

NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030

G

cytochrome P450, family 3, subfamily a, polypeptide 9

increases expression
multiple interactions

enilconazole results in increased expression of CYP3A5 mRNA; enilconazole results in increased expression of CYP3A5 protein
[clothianidin co-treated with enilconazole] results in increased expression of CYP3A5 protein; [enilconazole co-treated with thiacloprid] results in increased expression of CYP3A5 protein

NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422

G

cytochrome P450, family 51

decreases activity

enilconazole results in decreased activity of CYP51A1 protein

NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410
Ensembl chr 6:30,036,865...30,055,410

G

cytochrome P450 family 7 subfamily A member 1

decreases expression
multiple interactions

enilconazole results in decreased expression of CYP7A1 mRNA
[enilconazole co-treated with clothianidin] results in decreased expression of CYP7A1 mRNA; [thiacloprid co-treated with enilconazole] results in decreased expression of CYP7A1 mRNA
enilconazole results in decreased expression of CYP7A1 mRNA; enilconazole results in decreased expression of CYP7A1 protein

PMID:29451352 PMID:32194361 PMID:32201337 PMID:32814239 PMID:33426623

NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688

G

cytochrome P450 family 7 subfamily B member 1

decreases expression

enilconazole results in decreased expression of CYP7B1 mRNA

NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698

G

cytochrome P450 family 8 subfamily B member 1

increases expression

enilconazole results in increased expression of CYP8B1 mRNA

NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166

G

dynamin 1

decreases expression

enilconazole results in decreased expression of DNM1 mRNA

NCBI chr 3:15,604,782...15,648,654
Ensembl chr 3:15,604,784...15,648,538

G

elastin

decreases expression
multiple interactions

enilconazole results in decreased expression of ELN mRNA
[enilconazole co-treated with clothianidin] results in decreased expression of ELN mRNA; [thiacloprid co-treated with enilconazole] results in decreased expression of ELN mRNA

NCBI chr12:21,968,544...22,011,929
Ensembl chr12:21,968,544...22,011,928

G

estrogen receptor 1

multiple interactions

enilconazole binds to and results in increased activity of ESR1 protein

NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002

G

estrogen receptor 2

decreases expression
multiple interactions

enilconazole results in decreased expression of ESR2 mRNA
enilconazole binds to and results in increased activity of ESR2 protein

PMID:30853599 PMID:33049310

NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919

G

fatty acid binding protein 6

decreases expression

enilconazole results in decreased expression of FABP6 mRNA

NCBI chr10:28,063,603...28,068,276
Ensembl chr10:28,063,603...28,068,282

G

Fas cell surface death receptor

increases expression

enilconazole results in increased expression of FAS mRNA

NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591

G

fibroblast growth factor 19

decreases expression
increases expression

enilconazole results in decreased expression of FGF15 mRNA
enilconazole results in increased expression of FGF15 mRNA

PMID:29451352 PMID:32814239

NCBI chr 1:200,056,526...200,060,980
Ensembl chr 1:200,056,644...200,060,287

G

glucose-6-phosphatase catalytic subunit 1

decreases expression

enilconazole results in decreased expression of G6PC1 mRNA

PMID:32194361 PMID:32201337

NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804

G

glutathione peroxidase 1

increases expression

enilconazole results in increased expression of GPX1 mRNA

NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024

G

glutathione peroxidase 2

decreases expression

enilconazole results in decreased expression of GPX2 mRNA

NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877

G

glutathione-disulfide reductase

increases expression

enilconazole results in increased expression of GSR mRNA

NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661

G

glutathione synthetase

decreases expression

enilconazole results in decreased expression of GSS mRNA

NCBI chr 3:144,047,849...144,078,197
Ensembl chr 3:144,047,850...144,078,198

G

H2A.X variant histone

multiple interactions

[Maneb co-treated with mancozeb co-treated with iprodione co-treated with enilconazole co-treated with Chlorpyrifos co-treated with Diazinon co-treated with Dimethoate] results in increased expression of H2AX protein

NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
Ensembl chr 4:44,671,786...44,673,239

G

3-hydroxyanthranilate 3,4-dioxygenase

decreases expression

enilconazole results in decreased expression of HAAO mRNA

NCBI chr 6:10,845,235...10,864,863
Ensembl chr 6:10,845,771...10,864,877

G

3-hydroxy-3-methylglutaryl-CoA reductase

affects expression

enilconazole affects the expression of HMGCR mRNA

NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703

G

3-hydroxy-3-methylglutaryl-CoA synthase 1

affects expression

enilconazole affects the expression of HMGCS1 mRNA

NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100

G

hydroxysteroid (17-beta) dehydrogenase 13

decreases expression

enilconazole results in decreased expression of HSD17B13 mRNA

NCBI chr14:5,751,697...5,766,809
Ensembl chr14:5,752,132...5,768,166

G

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1

affects expression

enilconazole affects the expression of HSD3B1 mRNA

NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999

G

interferon gamma

increases expression

enilconazole results in increased expression of IFNG mRNA

PMID:27393971 PMID:32814239

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

G

interleukin 17A

multiple interactions
increases expression

enilconazole inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]
enilconazole results in increased expression of IL17A mRNA

PMID:22289359 PMID:32814239

NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889

G

interleukin 1 alpha

increases expression

enilconazole results in increased expression of IL1A mRNA

NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822

G

interleukin 1 beta

increases expression

enilconazole results in increased expression of IL1B mRNA

PMID:27393971 PMID:32814239

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 6

increases expression

enilconazole results in increased expression of IL6 mRNA

PMID:27393971 PMID:32201337 PMID:32814239

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

Jun proto-oncogene, AP-1 transcription factor subunit

increases expression

enilconazole results in increased expression of JUN mRNA

NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656

G

ketohexokinase

decreases expression

enilconazole results in decreased expression of KHK mRNA

NCBI chr 6:25,445,298...25,455,834
Ensembl chr 6:25,445,300...25,455,717

G

KLF transcription factor 4

affects expression
decreases expression

enilconazole affects the expression of KLF4 mRNA
enilconazole results in decreased expression of KLF4 mRNA

PMID:29106682 PMID:32814239

NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602

G

kyphoscoliosis peptidase

multiple interactions
decreases expression

[enilconazole co-treated with clothianidin] results in decreased expression of KY mRNA; [thiacloprid co-treated with enilconazole] results in decreased expression of KY mRNA
enilconazole results in decreased expression of KY mRNA

NCBI chr 8:103,086,959...103,126,305
Ensembl chr 8:103,086,630...103,126,024

G

lipocalin 2

increases expression

enilconazole results in increased expression of LCN2

NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095

G

luteinizing hormone subunit beta

decreases expression

enilconazole results in decreased expression of LHB protein

NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972

G

lipoprotein lipase

increases expression

enilconazole results in increased expression of LPL mRNA

NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249

G

lymphocyte antigen 6 family member D

decreases expression

enilconazole results in decreased expression of LY6D mRNA

NCBI chr 7:106,643,225...106,644,733
Ensembl chr 7:106,643,232...106,644,733

G

mitogen-activated protein kinase 8

increases expression

enilconazole results in increased expression of MAPK8 mRNA

NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981

G

multiple EGF-like-domains 11

multiple interactions
decreases expression

[enilconazole co-treated with clothianidin] results in decreased expression of MEGF11 mRNA; [thiacloprid co-treated with enilconazole] results in decreased expression of MEGF11 mRNA
enilconazole results in decreased expression of MEGF11 mRNA

NCBI chr 8:64,892,312...65,218,984
Ensembl chr 8:64,892,387...65,216,061

G

meprin A subunit beta

affects expression
decreases expression

enilconazole affects the expression of MEP1B mRNA
enilconazole results in decreased expression of MEP1B mRNA

PMID:29106682 PMID:32814239

NCBI chr18:12,366,126...12,392,840
Ensembl chr18:12,365,289...12,392,840

G

MLX interacting protein-like

decreases expression

enilconazole results in decreased expression of MLXIPL mRNA

NCBI chr12:21,541,608...21,577,120
Ensembl chr12:21,543,576...21,577,112

G

membrane metallo-endopeptidase

multiple interactions
increases expression

[enilconazole co-treated with clothianidin] results in increased expression of MME mRNA; [thiacloprid co-treated with enilconazole] results in increased expression of MME mRNA
enilconazole results in increased expression of MME mRNA

NCBI chr 2:147,686,913...147,803,808
Ensembl chr 2:147,722,086...147,803,792

G

microsomal triglyceride transfer protein

decreases expression

enilconazole results in decreased expression of MTTP mRNA

NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239

G

mucin 1, cell surface associated

affects expression
decreases expression

enilconazole affects the expression of MUC1 mRNA
enilconazole results in decreased expression of MUC1 mRNA

PMID:29106682 PMID:32814239

NCBI chr 2:174,635,989...174,640,738
Ensembl chr 2:174,635,995...174,640,733

G

mucin 17, cell surface associated

decreases expression

enilconazole results in decreased expression of MUC17 mRNA

NCBI chr12:19,527,251...19,536,924
Ensembl chr12:19,527,321...19,538,522

G

mucin 2, oligomeric mucus/gel-forming

affects expression
decreases expression

enilconazole affects the expression of MUC2 mRNA
enilconazole results in decreased expression of MUC2 mRNA

PMID:29106682 PMID:32814239

NCBI chr 1:196,799,494...196,831,740
Ensembl chr 1:196,799,517...196,831,756

G

nuclear receptor subfamily 0, group B, member 2

multiple interactions
decreases expression

[clothianidin co-treated with enilconazole] results in decreased expression of NR0B2 mRNA
enilconazole results in decreased expression of NR0B2 mRNA

NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609

G

nuclear receptor subfamily 1, group H, member 4

decreases expression
increases expression

enilconazole results in decreased expression of NR1H4 mRNA
enilconazole results in increased expression of NR1H4 mRNA

PMID:29451352 PMID:32814239

NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047

G

nuclear receptor subfamily 1, group I, member 2

multiple interactions
increases activity

[enilconazole co-treated with methidathion] results in increased activity of NR1I2 protein; enilconazole binds to and results in increased activity of NR1I2 protein; enilconazole inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]
enilconazole results in increased activity of NR1I2 protein

PMID:16565514 PMID:17438109 PMID:21115097 PMID:25028461 PMID:29973476 More...

NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658

G

nuclear receptor subfamily 1, group I, member 3

multiple interactions
affects response to substance

enilconazole binds to and results in increased activity of NR1I3 protein; enilconazole inhibits the reaction [Androstane-3,17-diol binds to and results in decreased activity of NR1I3 protein]
NR1I3 protein affects the susceptibility to enilconazole

PMID:18832183 PMID:27853109

NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906

G

pyruvate dehydrogenase kinase 4

decreases expression

enilconazole results in decreased expression of PDK4 mRNA

NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850

G

patatin-like phospholipase domain containing 3

decreases expression

enilconazole results in decreased expression of PNPLA3 mRNA

NCBI chr 7:115,293,538...115,314,077
Ensembl chr 7:115,293,538...115,314,077

G

peroxisome proliferator-activated receptor gamma

multiple interactions

enilconazole binds to and results in increased activity of PPARG protein

NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468

G

PPARG coactivator 1 alpha

decreases expression

enilconazole results in decreased expression of PPARGC1A mRNA

NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656

G

prostaglandin-endoperoxide synthase 2

multiple interactions

[enilconazole binds to and results in decreased activity of PTGS2 protein] which results in decreased chemical synthesis of and results in decreased secretion of Prostaglandin D2

NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188

G

retinoic acid receptor, alpha

increases activity

enilconazole results in increased activity of RARA protein

NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142

G

retinoic acid receptor, gamma

increases activity

enilconazole results in increased activity of RARG protein

NCBI chr 7:133,367,833...133,390,301
Ensembl chr 7:133,367,833...133,390,177

G

resistin like beta

affects expression

enilconazole affects the expression of RETNLB mRNA

NCBI chr11:51,983,482...51,985,368
Ensembl chr11:51,983,483...51,985,368

G

regulator of cell cycle

increases expression

enilconazole results in increased expression of RGCC mRNA

NCBI chr15:54,662,483...54,675,320
Ensembl chr15:54,662,483...54,681,141

G

RAR-related orphan receptor A

multiple interactions

enilconazole binds to and results in decreased activity of RORA protein

NCBI chr 8:69,301,635...70,034,741
Ensembl chr 8:69,301,733...70,025,931

G

stearoyl-CoA desaturase

decreases expression

enilconazole results in decreased expression of SCD mRNA

NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562

G

solute carrier family 10 member 1

decreases expression

enilconazole results in decreased expression of SLC10A1 mRNA

NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670

G

solute carrier family 10 member 2

increases expression

enilconazole results in increased expression of SLC10A2 mRNA

NCBI chr16:84,386,528...84,409,475
Ensembl chr16:84,374,862...84,409,475

G

solute carrier family 12 member 2

decreases expression

enilconazole results in decreased expression of SLC12A2 mRNA; enilconazole results in decreased expression of SLC12A2 protein

PMID:29106682 PMID:32814239

NCBI chr18:51,348,282...51,416,448
Ensembl chr18:51,348,302...51,416,440

G

solute carrier family 22 member 5

decreases expression

enilconazole results in decreased expression of SLC22A5 mRNA; enilconazole results in decreased expression of SLC22A5 protein

NCBI chr10:38,008,303...38,035,474
Ensembl chr10:38,008,311...38,035,309

G

solute carrier family 26 member 3

decreases expression

enilconazole results in decreased expression of SLC26A3 mRNA; enilconazole results in decreased expression of SLC26A3 protein

PMID:29106682 PMID:32814239

NCBI chr 6:48,023,892...48,064,829
Ensembl chr 6:48,023,892...48,064,772

G

solute carrier family 26 member 6

decreases expression

enilconazole results in decreased expression of SLC26A6 mRNA; enilconazole results in decreased expression of SLC26A6 protein

PMID:29106682 PMID:32814239

NCBI chr 8:109,558,968...109,569,778
Ensembl chr 8:109,559,642...109,569,778

G

solute carrier family 6 member 1

multiple interactions

[enilconazole co-treated with clothianidin] results in decreased expression of SLC6A1 mRNA; [thiacloprid co-treated with enilconazole] results in decreased expression of SLC6A1 mRNA

NCBI chr 4:147,448,961...147,482,295
Ensembl chr 4:147,466,965...147,482,293

G

solute carrier family 9 member A3

decreases expression

enilconazole results in decreased expression of SLC9A3 mRNA

PMID:29106682 PMID:32814239

NCBI chr 1:29,124,633...29,167,912
Ensembl chr 1:29,124,674...29,167,417

G

solute carrier organic anion transporter family, member 4a1

increases expression

enilconazole results in increased expression of SLCO4A1 mRNA

NCBI chr 3:167,559,177...167,578,307
Ensembl chr 3:167,559,316...167,578,305

G

superoxide dismutase 1

increases expression

enilconazole results in increased expression of SOD1 mRNA

NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249

G

superoxide dismutase 2

decreases expression

enilconazole results in decreased expression of SOD2 mRNA

NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189

G

steroidogenic acute regulatory protein

affects expression
decreases expression

enilconazole affects the expression of STAR mRNA
enilconazole results in decreased expression of STAR mRNA

PMID:30853599 PMID:36410587

NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672

G

sulfotransferase family 1B member 1

decreases expression

enilconazole results in decreased expression of SULT1B1 mRNA

NCBI chr14:20,492,763...20,505,491
Ensembl chr14:20,492,708...20,505,483

G

sulfotransferase family 1C member 2A

increases expression

enilconazole results in increased expression of SULT1C2 mRNA

NCBI chr 9:6,873,697...6,904,736
Ensembl chr 9:6,874,249...6,904,734

G

trefoil factor 3

decreases expression

enilconazole results in decreased expression of TFF3 mRNA

NCBI chr20:9,193,259...9,197,969
Ensembl chr20:9,193,262...9,198,054

G

thyroid hormone receptor alpha

multiple interactions

enilconazole binds to and results in decreased activity of THRA protein

NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936

G

tumor necrosis factor

increases expression

enilconazole results in increased expression of TNF mRNA

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

G

UDP glucuronosyltransferase family 2 member B7

decreases expression

enilconazole results in decreased expression of UGT2B7 mRNA

NCBI chr14:20,896,682...20,919,604
Ensembl chr14:20,896,682...20,919,604

fenamidone

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily A member 1

multiple interactions
increases expression

sulforaphane inhibits the reaction [fenamidone results in increased expression of ABCA1 mRNA]

NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170

G

acyl-CoA dehydrogenase, long chain

increases expression

fenamidone results in increased expression of ACADL mRNA

NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:68,333,980...68,372,220

G

acyl-CoA dehydrogenase short chain

increases expression

fenamidone results in increased expression of ACADS mRNA

NCBI chr12:41,493,650...41,502,897
Ensembl chr12:41,493,626...41,502,898

G

acyl-CoA dehydrogenase, very long chain

increases expression

fenamidone results in increased expression of ACADVL mRNA

NCBI chr10:54,732,875...54,738,102
Ensembl chr10:54,732,469...54,738,075

G

acyl-CoA synthetase bubblegum family member 1

increases expression

fenamidone results in increased expression of ACSBG1 mRNA

NCBI chr 8:54,991,294...55,047,276
Ensembl chr 8:54,991,296...55,047,391

G

actin alpha 2, smooth muscle

multiple interactions
increases expression

sulforaphane inhibits the reaction [fenamidone results in increased expression of ACTA2 mRNA]

NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554

G

actinin, alpha 1

increases expression

fenamidone results in increased expression of ACTN1 mRNA

NCBI chr 6:98,998,553...99,093,334
Ensembl chr 6:98,998,556...99,093,251

G

ADAM metallopeptidase with thrombospondin type 1 motif, 1

increases expression

fenamidone results in increased expression of ADAMTS1 mRNA

NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103

G

ADAM metallopeptidase with thrombospondin type 1 motif, 5

increases expression

fenamidone results in increased expression of ADAMTS5 mRNA

NCBI chr11:25,000,627...25,047,205
Ensembl chr11:25,000,637...25,047,205

G

ADAMTS-like 4

increases expression

fenamidone results in increased expression of ADAMTSL4 mRNA

NCBI chr 2:183,235,634...183,247,091
Ensembl chr 2:183,235,646...183,246,848

G

adenosine deaminase RNA specific B2

decreases expression

fenamidone results in decreased expression of ADARB2 mRNA

NCBI chr17:61,750,437...62,300,984
Ensembl chr17:61,756,067...62,300,831

G

adhesion G protein-coupled receptor E5

increases expression

fenamidone results in increased expression of ADGRE5 mRNA

NCBI chr19:24,397,972...24,418,648
Ensembl chr19:24,398,689...24,418,638

G

adhesion G protein-coupled receptor G6

increases expression

fenamidone results in increased expression of ADGRG6 mRNA

NCBI chr 1:8,812,889...8,954,239
Ensembl chr 1:8,812,904...8,954,123

G

adrenoceptor beta 2

increases expression

fenamidone results in increased expression of ADRB2 mRNA

NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512

G

AHNAK nucleoprotein

increases expression

fenamidone results in increased expression of AHNAK mRNA

NCBI chr 1:205,882,225...205,970,934
Ensembl chr 1:205,882,273...205,970,926

G

ajuba LIM protein

increases expression

fenamidone results in increased expression of AJUBA mRNA

NCBI chr15:28,019,775...28,031,537
Ensembl chr15:28,019,778...28,030,021

G

aldehyde dehydrogenase 4 family, member A1

increases expression

fenamidone results in increased expression of ALDH4A1 mRNA

NCBI chr 5:151,880,002...151,905,491
Ensembl chr 5:151,830,701...151,925,345

G

angiomotin-like 1

increases expression

fenamidone results in increased expression of AMOTL1 mRNA

NCBI chr 8:11,348,651...11,467,564
Ensembl chr 8:11,353,674...11,467,573

G

angiomotin like 2

increases expression

fenamidone results in increased expression of AMOTL2 mRNA

NCBI chr 8:103,303,368...103,319,161
Ensembl chr 8:103,302,992...103,318,910

G

angiopoietin-like 2

increases expression

fenamidone results in increased expression of ANGPTL2 mRNA

NCBI chr 3:16,517,185...16,547,024
Ensembl chr 3:16,517,420...16,548,178

G

ankyrin repeat and sterile alpha motif domain containing 1B

decreases expression

fenamidone results in decreased expression of ANKS1B mRNA

NCBI chr 7:24,313,339...25,479,307
Ensembl chr 7:24,312,843...25,477,693

G

annexin A2

increases expression

fenamidone results in increased expression of ANXA2 mRNA

NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658

G

annexin A3

increases expression

fenamidone results in increased expression of ANXA3 mRNA

NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617

G

Rho GTPase activating protein 18

increases expression

fenamidone results in increased expression of ARHGAP18 mRNA

NCBI chr 1:18,403,531...18,637,306
Ensembl chr 1:18,403,537...18,637,256

G

actin related protein 2/3 complex, subunit 1B

increases expression

fenamidone results in increased expression of ARPC1B mRNA

NCBI chr12:9,482,176...9,495,772
Ensembl chr12:9,480,831...9,495,747

G

N-acylsphingosine amidohydrolase 1

increases expression

fenamidone results in increased expression of ASAH1 mRNA

NCBI chr16:50,966,404...50,997,827
Ensembl chr16:50,966,229...51,008,233

G

argininosuccinate synthase 1

increases expression

fenamidone results in increased expression of ASS1 mRNA

NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903

G

activating transcription factor 3

increases expression

fenamidone results in increased expression of ATF3 mRNA

NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631

G

activating transcription factor 5

increases expression

fenamidone results in increased expression of ATF5 mRNA

NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:95,295,610...95,299,707

G

atlastin GTPase 1

decreases expression

fenamidone results in decreased expression of ATL1 mRNA

NCBI chr 6:88,377,168...88,475,242
Ensembl chr 6:88,377,239...88,475,204

G

ATPase H+ transporting V0 subunit D2

increases expression

fenamidone results in increased expression of ATP6V0D2 mRNA

NCBI chr 5:33,336,257...33,385,354
Ensembl chr 5:33,336,264...33,385,354

G

ATPase H+ transporting V0 subunit e1

increases expression

fenamidone results in increased expression of ATP6V0E mRNA

NCBI chr10:16,479,656...16,502,732
Ensembl chr10:16,479,567...16,524,434

G

Axl receptor tyrosine kinase

increases expression

fenamidone results in increased expression of AXL mRNA

NCBI chr 1:81,265,088...81,296,278
Ensembl chr 1:81,265,088...81,296,265

G

BAG cochaperone 3

increases expression

fenamidone results in increased expression of BAG3 mRNA

NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858

G

BCL11 transcription factor B

decreases expression

fenamidone results in decreased expression of BCL11B mRNA

NCBI chr 6:126,834,531...126,927,720
Ensembl chr 6:126,834,531...126,928,224

G

brain expressed, associated with NEDD4, 1

decreases expression

fenamidone results in decreased expression of BEAN1 mRNA

NCBI chr19:739,551...786,395
Ensembl chr19:739,551...787,537

G

basic helix-loop-helix family, member e41

increases expression

fenamidone results in increased expression of BHLHE41 mRNA

NCBI chr 4:178,834,264...178,838,618
Ensembl chr 4:178,834,271...178,838,468

G

BCL2 interacting protein 3

decreases expression

fenamidone results in decreased expression of BNIP3 mRNA

NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359

G

BTG anti-proliferation factor 2

increases expression

fenamidone results in increased expression of BTG2 mRNA

NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628

G

calcium dependent secretion activator

decreases expression

fenamidone results in decreased expression of CADPS mRNA

NCBI chr15:12,289,803...12,742,786
Ensembl chr15:12,290,262...12,742,779

G

caldesmon 1

increases expression

fenamidone results in increased expression of CALD1 mRNA

NCBI chr 4:63,265,781...63,446,938
Ensembl chr 4:63,265,942...63,446,932

G

calcium/calmodulin-dependent protein kinase IV

decreases expression

fenamidone results in decreased expression of CAMK4 mRNA

NCBI chr18:24,582,988...24,811,918
Ensembl chr18:24,585,269...24,802,487

G

calmodulin binding transcription activator 1

decreases expression

fenamidone results in decreased expression of CAMTA1 mRNA

NCBI chr 5:161,510,283...162,356,902
Ensembl chr 5:161,510,283...162,356,723

G

carbonic anhydrase 2

increases expression

fenamidone results in increased expression of CAR2 mRNA

NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818

G

caveolae associated protein 1

increases expression

fenamidone results in increased expression of CAVIN1 mRNA

NCBI chr10:85,884,100...85,896,136
Ensembl chr10:85,889,036...85,896,120

G

carbonyl reductase 3

increases expression

fenamidone results in increased expression of CBR3 mRNA

NCBI chr11:33,008,615...33,016,877
Ensembl chr11:33,008,615...33,016,875

G

coiled-coil domain containing 141

increases expression

fenamidone results in increased expression of CCDC141 mRNA

NCBI chr 3:61,948,614...62,109,968
Ensembl chr 3:61,948,646...62,110,079

G

cholecystokinin

decreases expression

fenamidone results in decreased expression of CCK mRNA

NCBI chr 8:121,153,499...121,160,194
Ensembl chr 8:121,153,500...121,160,084

G

cellular communication network factor 1

increases expression

fenamidone results in increased expression of CCN1 mRNA

NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484

G

cyclin D2

increases expression

fenamidone results in increased expression of CCND2 mRNA

NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495

G

cyclin D3

increases expression

fenamidone results in increased expression of CCND3 mRNA

NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371

G

cyclin G1

increases expression

fenamidone results in increased expression of CCNG1 mRNA

NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641

G

centriole, cilia and spindle-associated protein

decreases expression

fenamidone results in decreased expression of CCSAP mRNA

NCBI chr19:51,824,954...51,843,469
Ensembl chr19:51,826,994...51,842,753

G

CD151 molecule (Raph blood group)

increases expression

fenamidone results in increased expression of CD151 mRNA

NCBI chr 1:196,564,744...196,568,753
Ensembl chr 1:196,565,181...196,568,753

G

Cd63 molecule

increases expression

fenamidone results in increased expression of CD63 mRNA

NCBI chr 7:1,325,108...1,340,447
Ensembl chr 7:1,325,103...1,399,178

G

Cd68 molecule

increases expression

fenamidone results in increased expression of CD68 mRNA

NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697

G

CDC42 effector protein 1

increases expression

fenamidone results in increased expression of CDC42EP1 mRNA

NCBI chr 7:110,395,287...110,403,203
Ensembl chr 7:110,395,332...110,403,200

G

cyclin-dependent kinase inhibitor 1A

increases expression

fenamidone results in increased expression of CDKN1A mRNA

NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585

G

cyclin-dependent kinase inhibitor 1C

increases expression

fenamidone results in increased expression of CDKN1C mRNA

NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048

G

CCAAT/enhancer binding protein beta

increases expression

fenamidone results in increased expression of CEBPB mRNA

NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473

G

cell migration inducing hyaluronidase 1

increases expression

fenamidone results in increased expression of CEMIP mRNA

NCBI chr 1:137,906,921...138,062,430
Ensembl chr 1:137,908,920...138,062,415

G

cerebral endothelial cell adhesion molecule

increases expression

fenamidone results in increased expression of CERCAM mRNA

NCBI chr 3:13,118,150...13,155,960
Ensembl chr 3:13,142,107...13,155,956

G

ChaC glutathione-specific gamma-glutamylcyclotransferase 1

increases expression

fenamidone results in increased expression of CHAC1 mRNA

NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526

G

carbohydrate sulfotransferase 3

increases expression

fenamidone results in increased expression of CHST3 mRNA

NCBI chr20:28,114,386...28,152,046
Ensembl chr20:28,114,404...28,121,807

G

creatine kinase B

increases expression

fenamidone results in increased expression of CKB mRNA

NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315

G

C-type lectin domain containing 7A

increases expression

fenamidone results in increased expression of CLEC7A mRNA

NCBI chr 4:162,902,731...162,913,931
Ensembl chr 4:162,902,732...162,913,897

G

chloride intracellular channel 1

increases expression

fenamidone results in increased expression of CLIC1 mRNA

NCBI chr20:3,764,867...3,773,711
Ensembl chr20:3,761,461...3,773,712

G

CLN5, intracellular trafficking protein

increases expression

fenamidone results in increased expression of CLN5 mRNA

NCBI chr15:79,893,573...79,903,438
Ensembl chr15:79,893,548...79,903,438
Ensembl chr 2:79,893,548...79,903,438

G

calsyntenin 3

decreases expression

fenamidone results in decreased expression of CLSTN3 mRNA

NCBI chr 4:157,331,494...157,364,769
Ensembl chr 4:157,331,494...157,364,769

G

CKLF-like MARVEL transmembrane domain containing 3

increases expression

fenamidone results in increased expression of CMTM3 mRNA

NCBI chr19:622,563...630,721
Ensembl chr19:604,458...629,790

G

calponin 2

increases expression

fenamidone results in increased expression of CNN2 mRNA

NCBI chr 7:9,712,505...9,719,678
Ensembl chr 7:9,712,516...9,719,656

G

contactin associated protein family member 4

decreases expression

fenamidone results in decreased expression of CNTNAP4 mRNA

NCBI chr19:40,568,684...40,861,879
Ensembl chr19:40,568,684...40,854,656

G

collagen type XI alpha 1 chain

increases expression

fenamidone results in increased expression of COL11A1 mRNA

NCBI chr 2:201,820,715...202,013,853
Ensembl chr 2:201,820,715...202,013,853

G

collagen type XII alpha 1 chain

increases expression

fenamidone results in increased expression of COL12A1 mRNA

NCBI chr 8:80,547,592...80,665,665
Ensembl chr 8:80,547,593...80,665,686

G

collagen type IV alpha 5 chain

increases expression

fenamidone results in increased expression of COL4A5 mRNA

NCBI chr X:105,118,762...105,322,699
Ensembl chr X:105,118,820...105,322,692

G

collagen type IV alpha 6 chain

increases expression

fenamidone results in increased expression of COL4A6 mRNA

NCBI chr X:104,766,463...105,117,499
Ensembl chr X:104,766,957...105,117,500

G

collagen type VIII alpha 1 chain

increases expression

fenamidone results in increased expression of COL8A1 mRNA

NCBI chr11:42,776,851...42,906,432
Ensembl chr11:42,777,628...42,906,424

G

cytoplasmic polyadenylation element binding protein 1

increases expression

fenamidone results in increased expression of CPEB1 mRNA

NCBI chr 1:135,300,048...135,407,688
Ensembl chr 1:135,300,461...135,409,760

G

complexin 1

decreases expression

fenamidone results in decreased expression of CPLX1 mRNA

NCBI chr14:1,184,677...1,216,392

G

carnitine palmitoyltransferase 1A

increases expression

fenamidone results in increased expression of CPT1A mRNA

NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055

G

cartilage associated protein

increases expression

fenamidone results in increased expression of CRTAP mRNA

NCBI chr 8:114,047,929...114,067,636
Ensembl chr 8:114,047,933...114,067,631

G

colony stimulating factor 1

increases expression

fenamidone results in increased expression of CSF1 mRNA

NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704

G

cysteine and glycine-rich protein 1

increases expression

fenamidone results in increased expression of CSRP1 mRNA

NCBI chr13:47,158,171...47,179,388
Ensembl chr13:47,167,789...47,179,384

G

cystatin B

increases expression

fenamidone results in increased expression of CSTB mRNA

NCBI chr20:10,245,462...10,247,505
Ensembl chr20:10,245,462...10,247,526

G

catenin alpha 1

increases expression

fenamidone results in increased expression of CTNNA1 mRNA

NCBI chr18:26,728,246...26,860,911
Ensembl chr18:26,728,485...26,860,910

G

cathepsin D

increases expression

fenamidone results in increased expression of CTSD mRNA

NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488

G

cathepsin L

increases expression

fenamidone results in increased expression of CTSL mRNA

NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548

G

cathepsin Z

increases expression

fenamidone results in increased expression of CTSZ mRNA

NCBI chr 3:163,224,875...163,235,645
Ensembl chr 3:163,224,875...163,235,645

G

cytochrome b-245 alpha chain

increases expression

fenamidone results in increased expression of CYBA mRNA

NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721

G

dishevelled associated activator of morphogenesis 2

increases expression

fenamidone results in increased expression of DAAM2 mRNA

NCBI chr 9:11,428,913...11,546,982
Ensembl chr 9:11,428,724...11,545,497

G

DAB adaptor protein 2

increases expression

fenamidone results in increased expression of DAB2 mRNA

NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476

G

dicarbonyl and L-xylulose reductase

increases expression

fenamidone results in increased expression of DCXR mRNA

NCBI chr10:106,006,404...106,008,293

G

discoidin domain receptor tyrosine kinase 2

increases expression

fenamidone results in increased expression of DDR2 mRNA

NCBI chr13:82,193,623...82,318,229
Ensembl chr13:82,195,463...82,317,363

G

DENN domain containing 2B

increases expression

fenamidone results in increased expression of DENND2B mRNA

NCBI chr 1:163,544,075...163,734,736
Ensembl chr 1:163,544,074...163,694,680

G

DNA fragmentation factor subunit alpha

decreases expression

fenamidone results in decreased expression of DFFA mRNA

NCBI chr 5:159,540,715...159,553,639
Ensembl chr 5:159,540,715...159,553,633

G

dynamin 3

decreases expression

fenamidone results in decreased expression of DNM3 mRNA

NCBI chr13:74,359,043...74,838,135
Ensembl chr13:74,359,213...74,838,108

G

dedicator of cyto-kinesis 1

increases expression

fenamidone results in increased expression of DOCK1 mRNA

NCBI chr 1:189,467,143...189,983,777
Ensembl chr 1:189,467,143...189,983,768

G

dipeptidyl peptidase like 10

decreases expression

fenamidone results in decreased expression of DPP10 mRNA

NCBI chr13:34,584,420...36,269,292
Ensembl chr13:34,595,868...36,269,292

G

enoyl-CoA delta isomerase 2

increases expression

fenamidone results in increased expression of ECI2 mRNA

NCBI chr17:29,850,884...29,886,781
Ensembl chr17:29,870,391...29,886,781

G

ectodysplasin A2 receptor

increases expression

fenamidone results in increased expression of EDA2R mRNA

NCBI chr X:62,224,763...62,269,333
Ensembl chr X:62,228,229...62,269,268

G

eukaryotic translation elongation factor 1 alpha 2

decreases expression

fenamidone results in decreased expression of EEF1A2 mRNA

NCBI chr 3:168,265,893...168,275,071
Ensembl chr 3:168,195,357...168,275,071

G

EGF containing fibulin extracellular matrix protein 1

increases expression

fenamidone results in increased expression of EFEMP1 mRNA

NCBI chr14:102,610,813...102,690,027
Ensembl chr14:102,610,908...102,690,018

G

epidermal growth factor receptor

increases expression

fenamidone results in increased expression of EGFR mRNA

NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382

G

EH-domain containing 2

increases expression

fenamidone results in increased expression of EHD2 mRNA

NCBI chr 1:76,639,568...76,658,747
Ensembl chr 1:76,637,482...76,658,783

G

EH-domain containing 4

increases expression

fenamidone results in increased expression of EHD4 mRNA

NCBI chr 3:107,058,191...107,121,985
Ensembl chr 3:107,058,958...107,122,002

G

eukaryotic translation initiation factor 4E binding protein 1

increases expression

fenamidone results in increased expression of EIF4EBP1 mRNA

NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984

G

ELAV like RNA binding protein 2

decreases expression

fenamidone results in decreased expression of ELAVL2 mRNA

NCBI chr 5:105,960,872...106,086,463
Ensembl chr 5:105,960,875...106,109,097

G

ETS transcription factor ELK3

increases expression

fenamidone results in increased expression of ELK3 mRNA

NCBI chr 7:27,768,582...27,831,088
Ensembl chr 7:27,768,599...27,804,084

G

elastin

increases expression

fenamidone results in increased expression of ELN mRNA

NCBI chr12:21,968,544...22,011,929
Ensembl chr12:21,968,544...22,011,928

G

ELOVL fatty acid elongase 1

increases expression

fenamidone results in increased expression of ELOVL1 mRNA

NCBI chr 5:131,961,478...131,965,961
Ensembl chr 5:131,961,322...131,965,958

G

ecto-NOX disulfide-thiol exchanger 1

decreases expression

fenamidone results in decreased expression of ENOX1 mRNA

NCBI chr15:52,517,833...53,079,752
Ensembl chr15:52,515,178...53,079,749

G

endothelial PAS domain protein 1

increases expression

fenamidone results in increased expression of EPAS1 mRNA

NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228

G

Eph receptor A2

increases expression

fenamidone results in increased expression of EPHA2 mRNA

NCBI chr 5:153,605,644...153,634,115
Ensembl chr 5:153,605,644...153,634,117

G

epoxide hydrolase 1

increases expression

fenamidone results in increased expression of EPHX1 mRNA

NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235

G

electron transfer flavoprotein subunit beta

increases expression

fenamidone results in increased expression of ETFB mRNA

NCBI chr 1:93,851,908...93,866,072
Ensembl chr 1:93,851,858...93,866,068

G

ETS proto-oncogene 1, transcription factor

increases expression

fenamidone results in increased expression of ETS1 mRNA

NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010

G

EvC ciliary complex subunit 1

increases expression

fenamidone results in increased expression of EVC mRNA

NCBI chr14:73,456,181...73,498,955
Ensembl chr14:73,456,222...73,498,099

G

coagulation factor II (thrombin) receptor

increases expression

fenamidone results in increased expression of F2R mRNA

NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870

G

coagulation factor III, tissue factor

increases expression

fenamidone results in increased expression of F3 mRNA

NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668

G

Fas apoptotic inhibitory molecule 2

decreases expression

fenamidone results in decreased expression of FAIM2 mRNA

NCBI chr 7:130,632,368...130,659,353
Ensembl chr 7:130,633,348...130,659,168

G

FAT atypical cadherin 1

increases expression

fenamidone results in increased expression of FAT1 mRNA

NCBI chr16:47,177,253...47,296,261
Ensembl chr16:47,177,248...47,296,107

G

fibrillin 1

increases expression

fenamidone results in increased expression of FBN1 mRNA

NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889

G

f-box protein 9

decreases expression

fenamidone results in decreased expression of FBXO9 mRNA

NCBI chr 8:78,958,482...78,984,015
Ensembl chr 8:78,958,483...78,983,949

G

Fibroblast growth factor receptor 1

increases expression

fenamidone results in increased expression of FGFR1 mRNA

NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350

G

fibroblast growth factor receptor 3

increases expression

fenamidone results in increased expression of FGFR3 mRNA

NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341

G

FKBP prolyl isomerase 10

increases expression

fenamidone results in increased expression of FKBP10 mRNA

NCBI chr10:85,345,434...85,357,998
Ensembl chr10:85,346,126...85,427,330

G

FKBP prolyl isomerase 9

increases expression

fenamidone results in increased expression of FKBP9 mRNA

NCBI chr 4:86,106,256...86,156,723
Ensembl chr 4:86,106,282...86,156,721

G

filamin A

increases expression

fenamidone results in increased expression of FLNA mRNA

NCBI chr X:152,007,758...152,034,266
Ensembl chr X:152,007,758...152,031,052

G

filamin B

increases expression

fenamidone results in increased expression of FLNB mRNA

NCBI chr15:16,961,999...17,095,059
Ensembl chr15:16,962,003...17,095,006

G

filamin C

increases expression

fenamidone results in increased expression of FLNC mRNA

NCBI chr 4:58,034,088...58,061,882
Ensembl chr 4:58,034,189...58,061,844

G

fibronectin 1

increases expression

fenamidone results in increased expression of FN1 mRNA

NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678

G

FERM domain containing 8

increases expression

fenamidone results in increased expression of FRMD8 mRNA

NCBI chr 1:203,143,216...203,163,868
Ensembl chr 1:203,143,218...203,163,870

G

frizzled class receptor 7

increases expression

fenamidone results in increased expression of FZD7 mRNA

NCBI chr 9:60,931,433...60,934,252
Ensembl chr 9:60,930,875...60,935,781

G

glutamate decarboxylase 1

decreases expression

fenamidone results in decreased expression of GAD1 mRNA

NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333

G

glutamate decarboxylase 2

decreases expression

fenamidone results in decreased expression of GAD2 mRNA

NCBI chr17:84,763,630...84,826,155
Ensembl chr17:84,763,628...84,826,155

G

growth arrest and DNA-damage-inducible, alpha

increases expression

fenamidone results in increased expression of GADD45A mRNA

NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115

G

polypeptide N-acetylgalactosaminyltransferase 9

decreases expression

fenamidone results in decreased expression of GALNT9 mRNA

NCBI chr12:46,050,395...46,128,626
Ensembl chr12:46,050,413...46,128,578

G

growth differentiation factor 15

increases expression

fenamidone results in increased expression of GDF15 mRNA

NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055

G

gap junction protein, delta 2

decreases expression

fenamidone results in decreased expression of GJD2 mRNA

NCBI chr 3:100,771,450...100,776,134
Ensembl chr 3:100,772,062...100,775,061

G

glycosylated lysosomal membrane protein

increases expression

fenamidone results in increased expression of GLMP mRNA

NCBI chr 2:173,794,273...173,797,863
Ensembl chr 2:173,794,255...173,799,960

G

glycine receptor, alpha 2

decreases expression

fenamidone results in decreased expression of GLRA2 mRNA

NCBI chr X:29,020,377...29,241,666
Ensembl chr X:29,020,557...29,241,666

G

glutaminase

decreases expression

fenamidone results in decreased expression of GLS mRNA

NCBI chr 9:49,344,616...49,416,900
Ensembl chr 9:49,344,781...49,416,900

G

glycolipid transfer protein

increases expression

fenamidone results in increased expression of GLTP mRNA

NCBI chr12:41,907,168...41,927,321
Ensembl chr12:41,907,144...41,927,319

G

G protein subunit gamma 12

increases expression

fenamidone results in increased expression of GNG12 mRNA

NCBI chr 4:96,011,118...96,134,767
Ensembl chr 4:96,010,952...96,134,712

G

glycoprotein nmb

increases expression

fenamidone results in increased expression of GPNMB mRNA

NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367

G

G protein-coupled receptor 22

decreases expression

fenamidone results in decreased expression of GPR22 mRNA

NCBI chr 6:48,309,619...48,317,864
Ensembl chr 6:48,310,505...48,317,486

G

G-protein coupled receptor 88

decreases expression

fenamidone results in decreased expression of GPR88 mRNA

NCBI chr 2:204,191,443...204,199,576
Ensembl chr 2:204,191,427...204,199,733

G

glutathione peroxidase 1

increases expression

fenamidone results in increased expression of GPX1 mRNA

NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024

G

glutamate ionotropic receptor kainate type subunit 3

decreases expression

fenamidone results in decreased expression of GRIK3 mRNA

NCBI chr 5:137,767,865...137,989,617
Ensembl chr 5:137,767,865...137,984,307

G

granulin precursor

increases expression

fenamidone results in increased expression of GRN mRNA

NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775

G

glutathione synthetase

increases expression

fenamidone results in increased expression of GSS mRNA

NCBI chr 3:144,047,849...144,078,197
Ensembl chr 3:144,047,850...144,078,198

G

glutathione S-transferase mu 1

multiple interactions
increases expression

sulforaphane inhibits the reaction [fenamidone results in increased expression of GSTM1 mRNA]

NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411

G

G-2 and S-phase expressed 1

increases expression

fenamidone results in increased expression of GTSE1 mRNA

NCBI chr 7:116,949,997...116,966,826
Ensembl chr 7:116,950,053...116,966,806

G

glucoside xylosyltransferase 2

increases expression

fenamidone results in increased expression of GXYLT2 mRNA

NCBI chr 4:133,347,230...133,449,708
Ensembl chr 4:133,347,499...133,449,454

G

3-hydroxyacyl-CoA dehydratase 4

increases expression

fenamidone results in increased expression of HACD4 mRNA

NCBI chr 5:102,887,597...102,915,376
Ensembl chr 5:102,887,588...102,915,338

G

hydroxyacyl-CoA dehydrogenase

increases expression

fenamidone results in increased expression of HADH mRNA

NCBI chr 2:219,787,935...219,830,335
Ensembl chr 2:219,787,927...219,830,353

G

hyaluronan and proteoglycan link protein 1

decreases expression

fenamidone results in decreased expression of HAPLN1 mRNA

NCBI chr 2:20,631,640...20,696,388
Ensembl chr 2:20,631,640...20,693,777

G

heparin-binding EGF-like growth factor

increases expression

fenamidone results in increased expression of HBEGF mRNA

NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441

G

heme oxygenase 1

multiple interactions
increases expression

sulforaphane inhibits the reaction [fenamidone results in increased expression of HMOX1 mRNA]

NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079

G

heparan sulfate-glucosamine 3-sulfotransferase 2

decreases expression

fenamidone results in decreased expression of HS3ST2 mRNA

NCBI chr 1:175,956,161...176,077,400
Ensembl chr 1:175,956,157...176,077,399

G

heparan sulfate proteoglycan 2

increases expression

fenamidone results in increased expression of HSPG2 mRNA

NCBI chr 5:149,677,437...149,778,594
Ensembl chr 5:149,677,476...149,778,594

G

hyaluronidase 1

increases expression

fenamidone results in increased expression of HYAL1 mRNA

NCBI chr 8:108,250,668...108,254,519
Ensembl chr 8:108,250,667...108,260,210

G

intercellular adhesion molecule 1

increases expression

fenamidone results in increased expression of ICAM1 mRNA

NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438

G

immediate early response 3

increases expression

fenamidone results in increased expression of IER3 mRNA

NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583

G

IFI30, lysosomal thiol reductase

increases expression

fenamidone results in increased expression of IFI30 mRNA

NCBI chr16:18,675,590...18,679,655
Ensembl chr16:18,675,613...18,681,175

G

interferon induced transmembrane protein 2

increases expression

fenamidone results in increased expression of IFITM2 mRNA

NCBI chr 1:196,051,539...196,052,719
Ensembl chr 1:196,051,537...196,052,741

G

immunoglobulin superfamily, DCC subclass, member 4

increases expression

fenamidone results in increased expression of IGDCC4 mRNA

NCBI chr 8:65,621,893...65,657,651
Ensembl chr 8:65,621,897...65,657,648

G

insulin-like growth factor binding protein 3

increases expression

fenamidone results in increased expression of IGFBP3 mRNA

NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083

G

insulin-like growth factor binding protein-like 1

increases expression

fenamidone results in increased expression of IGFBPL1 mRNA

NCBI chr 5:60,076,428...60,091,833
Ensembl chr 5:60,076,429...60,091,833

G

interleukin 1 receptor accessory protein

increases expression

fenamidone results in increased expression of IL1RAP mRNA

NCBI chr11:74,062,999...74,199,530
Ensembl chr11:74,070,304...74,199,530

G

inverted formin 2

increases expression

fenamidone results in increased expression of INF2 mRNA

NCBI chr 6:131,649,162...131,675,944
Ensembl chr 6:131,649,211...131,675,941

G

interaction protein for cytohesin exchange factors 1

decreases expression

fenamidone results in decreased expression of IPCEF1 mRNA

NCBI chr 1:43,237,903...43,451,735
Ensembl chr 1:43,269,202...43,427,969

G

interleukin-1 receptor-associated kinase 1

increases expression

fenamidone results in increased expression of IRAK1 mRNA

NCBI chr X:151,768,621...151,778,521
Ensembl chr X:151,768,777...151,778,521

G

integrin subunit alpha 3

increases expression

fenamidone results in increased expression of ITGA3 mRNA

NCBI chr10:79,990,160...80,022,206
Ensembl chr10:79,990,161...80,022,118

G

integrin subunit alpha 5

increases expression

fenamidone results in increased expression of ITGA5 mRNA

NCBI chr 7:134,478,963...134,502,837
Ensembl chr 7:134,478,968...134,502,837

G

integrin subunit alpha 6

increases expression

fenamidone results in increased expression of ITGA6 mRNA

NCBI chr 3:56,604,512...56,689,428
Ensembl chr 3:56,617,268...56,689,428

G

integrin subunit alpha 7

increases expression

fenamidone results in increased expression of ITGA7 mRNA

NCBI chr 7:1,360,125...1,388,886
Ensembl chr 7:1,359,940...1,388,450

G

integrin subunit alpha V

increases expression

fenamidone results in increased expression of ITGAV mRNA

NCBI chr 3:68,838,514...68,926,653
Ensembl chr 3:68,838,189...68,926,639

G

integrin subunit beta 1

increases expression

fenamidone results in increased expression of ITGB1 mRNA

NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195

G

ITPR interacting domain containing 2

increases expression

fenamidone results in increased expression of ITPRID2 mRNA

NCBI chr 3:64,536,707...64,573,978
Ensembl chr 3:64,536,707...64,573,978

G

KN motif and ankyrin repeat domains 4

increases expression

fenamidone results in increased expression of KANK4 mRNA

NCBI chr 5:113,401,491...113,465,526
Ensembl chr 5:113,402,468...113,465,555

G

potassium voltage-gated channel subfamily A member 1

decreases expression

fenamidone results in decreased expression of KCNA1 mRNA

NCBI chr 4:159,464,223...159,472,905
Ensembl chr 4:159,464,188...159,472,682

G

potassium voltage-gated channel subfamily C member 2

decreases expression

fenamidone results in decreased expression of KCNC2 mRNA

NCBI chr 7:47,700,035...47,883,979
Ensembl chr 7:47,700,288...47,883,968

G

potassium voltage-gated channel subfamily H member 3

decreases expression
multiple interactions

fenamidone results in decreased expression of KCNH3 mRNA
sulforaphane inhibits the reaction [fenamidone results in decreased expression of KCNH3 mRNA]

NCBI chr 7:130,365,593...130,383,859
Ensembl chr 7:130,366,011...130,383,855

G

potassium voltage-gated channel modifier subfamily V member 1

decreases expression

fenamidone results in decreased expression of KCNV1 mRNA

NCBI chr 7:76,260,695...76,269,170
Ensembl chr 7:76,260,695...76,269,170

G

kinesin family member 1C

increases expression

fenamidone results in increased expression of KIF1C mRNA

NCBI chr10:55,414,412...55,444,587
Ensembl chr10:55,415,900...55,443,545

G

kinesin family member 5A

decreases expression

fenamidone results in decreased expression of KIF5A mRNA

NCBI chr 7:63,051,894...63,089,024
Ensembl chr 7:63,049,424...63,092,858

G

kirre like nephrin family adhesion molecule 1

increases expression

fenamidone results in increased expression of KIRREL1 mRNA

NCBI chr 2:172,521,644...172,615,057
Ensembl chr 2:172,525,245...172,615,299

G

KLF transcription factor 3

increases expression

fenamidone results in increased expression of KLF3 mRNA

NCBI chr14:43,474,767...43,505,801
Ensembl chr14:43,474,767...43,497,209

G

KLF transcription factor 4

increases expression

fenamidone results in increased expression of KLF4 mRNA

NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602

G

laminin subunit alpha 5

increases expression

fenamidone results in increased expression of LAMA5 mRNA

NCBI chr 3:167,270,296...167,318,370
Ensembl chr 3:167,270,296...167,318,451

G

laminin subunit beta 1

increases expression

fenamidone results in increased expression of LAMB1 mRNA

NCBI chr 6:47,835,492...47,902,585
Ensembl chr 6:47,835,525...47,902,585

G

laminin subunit beta 2

increases expression

fenamidone results in increased expression of LAMB2 mRNA

NCBI chr 8:109,178,367...109,190,552
Ensembl chr 8:109,178,409...109,190,549

G

laminin subunit gamma 1

increases expression

fenamidone results in increased expression of LAMC1 mRNA

NCBI chr13:65,374,372...65,501,492
Ensembl chr13:65,374,372...65,501,492

G

large tumor suppressor kinase 2

increases expression

fenamidone results in increased expression of LATS2 mRNA

NCBI chr15:31,825,068...31,877,193
Ensembl chr15:31,825,092...31,877,220

G

galectin 1

increases expression

fenamidone results in increased expression of LGALS1 mRNA

NCBI chr 7:110,485,239...110,488,345
Ensembl chr 7:110,481,392...110,488,345

G

galectin 3

increases expression

fenamidone results in increased expression of LGALS3 mRNA

NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025

G

leucine-rich, glioma inactivated 1

decreases expression

fenamidone results in decreased expression of LGI1 mRNA

NCBI chr 1:236,043,269...236,084,617
Ensembl chr 1:236,042,954...236,084,616

G

LHFPL tetraspan subfamily member 6

increases expression

fenamidone results in increased expression of LHFPL6 mRNA

NCBI chr 2:137,126,485...137,324,442
Ensembl chr 2:137,126,509...137,324,443

G

LIF, interleukin 6 family cytokine

increases expression

fenamidone results in increased expression of LIF mRNA

NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482

G

LIM domain and actin binding 1

multiple interactions
increases expression

sulforaphane inhibits the reaction [fenamidone results in increased expression of LIMA1 mRNA]

NCBI chr 7:130,901,717...131,001,512
Ensembl chr 7:130,901,717...131,001,473

G

lipase A, lysosomal acid type

increases expression

fenamidone results in increased expression of LIPA mRNA

NCBI chr 1:232,024,351...232,057,735
Ensembl chr 1:232,024,356...232,057,633

G

lipopolysaccharide-induced TNF factor

increases expression

fenamidone results in increased expression of LITAF mRNA

NCBI chr10:4,656,308...4,692,981
Ensembl chr10:4,625,552...4,692,763

G

leiomodin 1

increases expression

fenamidone results in increased expression of LMOD1 mRNA

NCBI chr13:46,754,048...46,796,186
Ensembl chr13:46,754,033...46,794,900

G

LIM domain containing preferred translocation partner in lipoma

increases expression

fenamidone results in increased expression of LPP mRNA

NCBI chr11:75,787,326...76,426,646
Ensembl chr11:75,797,078...76,422,597

G

LDL receptor related protein 2

increases expression

fenamidone results in increased expression of LRP2 mRNA

NCBI chr 3:54,189,305...54,346,769
Ensembl chr 3:54,189,308...54,346,708

G

LDL receptor related protein 5

increases expression

fenamidone results in increased expression of LRP5 mRNA

NCBI chr 1:200,814,247...200,917,581
Ensembl chr 1:200,814,250...200,917,581

G

leucine-rich repeat kinase 1

increases expression

fenamidone results in increased expression of LRRK1 mRNA

NCBI chr 1:119,844,360...119,972,885
Ensembl chr 1:119,845,146...119,979,734

G

leucine-rich repeat kinase 2

increases expression

fenamidone results in increased expression of LRRK2 mRNA

NCBI chr 7:122,826,696...122,987,711
Ensembl chr 7:122,826,696...122,987,703

G

LSM11, U7 small nuclear RNA associated

decreases expression

fenamidone results in decreased expression of LSM11 mRNA

NCBI chr10:30,367,841...30,385,956
Ensembl chr10:30,370,727...30,385,944

G

leucine zipper tumor suppressor 1

decreases expression

fenamidone results in decreased expression of LZTS1 mRNA

NCBI chr16:20,542,756...20,598,204
Ensembl chr16:20,542,809...20,598,203

G

MAF bZIP transcription factor F

increases expression

fenamidone results in increased expression of MAFF mRNA

NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851

G

mannosidase, alpha, class 2B, member 1

increases expression

fenamidone results in increased expression of MAN2B1 mRNA

NCBI chr19:23,055,092...23,074,398
Ensembl chr19:23,055,097...23,074,389

G

mannosidase, alpha, class 2B, member 2

increases expression

fenamidone results in increased expression of MAN2B2 mRNA

NCBI chr14:73,969,079...73,994,089
Ensembl chr14:73,969,003...74,004,281

G

mitogen-activated protein kinase kinase kinase 20

increases expression

fenamidone results in increased expression of MAP3K20 mRNA

NCBI chr 3:57,130,539...57,289,943
Ensembl chr 3:57,130,551...57,289,626

G

MAPK activated protein kinase 3

increases expression

fenamidone results in increased expression of MAPKAPK3 mRNA

NCBI chr 8:107,929,754...107,963,638
Ensembl chr 8:107,929,762...107,963,568

G

minichromosome maintenance complex component 2

increases expression

fenamidone results in increased expression of MCM2 mRNA

NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847

G

midkine

increases expression

fenamidone results in increased expression of MDK mRNA

NCBI chr 3:77,901,134...77,903,997
Ensembl chr 3:77,901,158...77,903,130

G

moesin

increases expression

fenamidone results in increased expression of MSN mRNA

NCBI chr X:60,996,043...61,064,011
Ensembl chr X:60,995,951...61,065,628

G

methionine sulfoxide reductase B3

increases expression

fenamidone results in increased expression of MSRB3 mRNA

NCBI chr 7:56,260,985...56,426,004
Ensembl chr 7:56,303,308...56,425,496

G

methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1

increases expression

fenamidone results in increased expression of MTHFD1 mRNA

NCBI chr 6:94,977,862...95,045,375
Ensembl chr 6:94,977,862...95,045,372

G

MYB proto-oncogene like 1

increases expression

fenamidone results in increased expression of MYBL1 mRNA

NCBI chr 5:9,582,905...9,618,179
Ensembl chr 5:9,582,934...9,618,183

G

myosin, heavy chain 9

increases expression

fenamidone results in increased expression of MYH9 mRNA

NCBI chr 7:109,343,718...109,424,457
Ensembl chr 7:109,343,706...109,424,457

G

myosin light chain 12A

increases expression

fenamidone results in increased expression of MYL12A mRNA

NCBI chr 9:110,891,970...110,899,655
Ensembl chr 9:110,873,959...110,916,580

G

myosin light chain 9

increases expression

fenamidone results in increased expression of MYL9 mRNA

NCBI chr 3:145,281,943...145,288,333
Ensembl chr 3:145,281,937...145,288,333

G

myoferlin

increases expression

fenamidone results in increased expression of MYOF mRNA

NCBI chr 1:235,673,666...235,822,413
Ensembl chr 1:235,673,666...235,822,334

G

Ngfi-A binding protein 2

increases expression

fenamidone results in increased expression of NAB2 mRNA

NCBI chr 7:63,497,589...63,504,105
Ensembl chr 7:63,497,589...63,503,989

G

NACC family member 2

increases expression

fenamidone results in increased expression of NACC2 mRNA

NCBI chr 3:8,879,952...8,946,660
Ensembl chr 3:8,883,065...8,946,660

G

nucleosome assembly protein 1-like 2

decreases expression

fenamidone results in decreased expression of NAP1L2 mRNA

NCBI chr X:68,174,051...68,176,449
Ensembl chr X:68,173,987...68,176,666

G

NSF attachment protein beta

decreases expression

fenamidone results in decreased expression of NAPB mRNA

NCBI chr 3:136,132,248...136,179,280
Ensembl chr 3:136,133,428...136,179,345

G

nuclear prelamin A recognition factor

decreases expression

fenamidone results in decreased expression of NARF mRNA

NCBI chr10:106,519,508...106,537,494
Ensembl chr10:106,519,444...106,537,486

G

NIMA-related kinase 6

increases expression

fenamidone results in increased expression of NEK6 mRNA

NCBI chr 3:22,284,269...22,356,302
Ensembl chr 3:22,284,279...22,395,990

G

nestin

increases expression

fenamidone results in increased expression of NES mRNA

NCBI chr 2:173,437,867...173,447,777
Ensembl chr 2:173,438,734...173,447,777

G

neuropilin and tolloid like 1

decreases expression

fenamidone results in decreased expression of NETO1 mRNA

NCBI chr18:79,635,633...79,753,913
Ensembl chr18:79,635,633...79,749,030

G

nuclear factor kappa B subunit 2

increases expression

fenamidone results in increased expression of NFKB2 mRNA

NCBI chr 1:245,164,586...245,173,225
Ensembl chr 1:245,165,950...245,173,213

G

nicotinamide nucleotide transhydrogenase

increases expression

fenamidone results in increased expression of NNT mRNA

NCBI chr 2:51,411,413...51,505,125
Ensembl chr 2:51,411,413...51,504,823

G

notch receptor 1

increases expression

fenamidone results in increased expression of NOTCH1 mRNA

NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531

G

notch receptor 3

increases expression

fenamidone results in increased expression of NOTCH3 mRNA

NCBI chr 7:11,132,984...11,184,025
Ensembl chr 7:11,133,706...11,184,025

G

natriuretic peptide receptor 2

increases expression

fenamidone results in increased expression of NPR2 mRNA

NCBI chr 5:57,883,171...57,901,590
Ensembl chr 5:57,883,171...57,901,580

G

NAD(P)H quinone dehydrogenase 1

increases expression
multiple interactions

fenamidone results in increased expression of NQO1 mRNA
sulforaphane inhibits the reaction [fenamidone results in increased expression of NQO1 mRNA]

NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557

G

neuregulin 1

increases expression

fenamidone results in increased expression of NRG1 mRNA

NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884

G

neurexin 3

decreases expression

fenamidone results in decreased expression of NRXN3 mRNA

NCBI chr 6:107,641,760...109,272,849
Ensembl chr 6:107,641,780...109,272,044

G

NUAK family kinase 2

increases expression

fenamidone results in increased expression of NUAK2 mRNA

NCBI chr13:43,753,454...43,770,604
Ensembl chr13:43,753,832...43,770,604

G

nucleoporin 93

increases expression

fenamidone results in increased expression of NUP93 mRNA

NCBI chr19:10,684,214...10,788,009
Ensembl chr19:10,682,075...10,788,026

G

neurexophilin 1

decreases expression

fenamidone results in decreased expression of NXPH1 mRNA

NCBI chr 4:36,998,068...37,311,135
Ensembl chr 4:36,997,669...37,311,132

G

neurexophilin 2

decreases expression

fenamidone results in decreased expression of NXPH2 mRNA

NCBI chr 3:5,986,175...5,988,525
Ensembl chr 3:5,756,621...5,987,008

G

osteoclast stimulating factor 1

increases expression

fenamidone results in increased expression of OSTF1 mRNA

NCBI chr 1:216,002,037...216,049,226
Ensembl chr 1:216,002,044...216,049,221

G

purinergic receptor P2Y2

increases expression

fenamidone results in increased expression of P2RY2 mRNA

NCBI chr 1:155,352,050...155,367,423
Ensembl chr 1:155,351,165...155,367,632

G

palladin, cytoskeletal associated protein

increases expression

fenamidone results in increased expression of PALLD mRNA