CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: manganese(II) sulfate
Accession: CHEBI:86360
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Definition: A metal sulfate in which the metal component is manganese in the +2 oxidation state.
Synonyms: related_synonym: Formula=MnO4S; InChI=1S/Mn.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2; InChIKey=SQQMAOCOWKFBNP-UHFFFAOYSA-L; Manganese monosulfate; Manganese sulfate anhydrous; Manganese sulphate; Manganous sulfate; MnSO4; SMILES=[Mn++].[O-]S([O-])(=O)=O; manganese(2+) sulfate; manganese(2+) sulphate; manganese(II) sulphate
xref: CAS:7785-87-7
xref_mesh: MESH:C039798
xref: MetaCyc:CPD0-1608; Reaxys:11343137; Reaxys:14270535; Reaxys:28059988; Wikipedia:Manganese(II)_sulfate
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Cxcl2
C-X-C motif chemokine ligand 2
increases expression
EXP
manganese sulfate results in increased expression of CXCL2 mRNA
CTD
PMID:11708899
NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
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Glul
glutamate-ammonia ligase
decreases expression
EXP
manganese sulfate results in decreased expression of GLUL mRNA; manganese sulfate results in decreased expression of GLUL protein
CTD
PMID:16943606
NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108
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Hspa4
heat shock protein family A (Hsp70) member 4
increases expression
EXP
manganese sulfate results in increased expression of HSPA4 mRNA
CTD
PMID:26097037
NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001
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Il6
interleukin 6
multiple interactions increases expression
ISO
Lipopolysaccharides promotes the reaction [manganese sulfate results in increased expression of IL6 protein]; manganese sulfate promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein]
CTD
PMID:15601679
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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Mt1
metallothionein 1
decreases expression
EXP
manganese sulfate results in decreased expression of MT1A mRNA
CTD
PMID:12387356
NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049 Ensembl chr17:10,826,032...10,827,049
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Nos1
nitric oxide synthase 1
decreases expression
EXP
manganese sulfate results in decreased expression of NOS1 mRNA
CTD
PMID:16476481
NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
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Slc1a3
solute carrier family 1 member 3
decreases expression
EXP
manganese sulfate results in decreased expression of SLC1A3 mRNA
CTD
PMID:12387356
NCBI chr 2:57,755,495...57,830,605
Ensembl chr 2:57,755,497...57,830,605
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Tgfb1
transforming growth factor, beta 1
decreases expression
EXP
manganese sulfate results in decreased expression of TGFB1 mRNA
CTD
PMID:16476481
NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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Th
tyrosine hydroxylase
decreases expression
EXP
manganese sulfate results in decreased expression of TH mRNA
CTD
PMID:16943606
NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
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Tnf
tumor necrosis factor
multiple interactions increases expression
ISO
Lipopolysaccharides promotes the reaction [manganese sulfate results in increased expression of TNF protein]; manganese sulfate promotes the reaction [Lipopolysaccharides results in increased expression of TNF protein]
CTD
PMID:15601679
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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