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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:conazole antifungal agent
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Accession:CHEBI:86323 term browser browse the term
Definition:A compound that has a structure that is related to miconazole, contains an azole (imidazole or triazole) moiety, and has significant systemic antifungal properties. They inhibit cytochrome P450-dependent enzymes (particularly C14-demethylase) involved in the biosynthesis of ergosterol, which is required for fungal cell membrane structure and function.
Synonyms:related_synonym: azole antibiotic;   azole antibiotics;   conazole antifungal agents
 alt_id: CHEBI:60593


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    • Term paths to the root
    Path 1
    Term Annotations click to browse term
      CHEBI ontology 19874
        role 19844
          biological role 19842
            antimicrobial agent 18240
              antifungal agent 17158
                conazole antifungal agent 6547
                  conazole antifungal drug + 1609
                  conazole fungicide + 5749
                  diniconazole-M + 8
    Path 2
    Term Annotations click to browse term
      CHEBI ontology 19874
        subatomic particle 19872
          composite particle 19872
            hadron 19872
              baryon 19872
                nucleon 19872
                  atomic nucleus 19872
                    atom 19872
                      main group element atom 19811
                        p-block element atom 19811
                          carbon group element atom 19751
                            carbon atom 19748
                              organic molecular entity 19748
                                organic molecule 19700
                                  organic cyclic compound 19490
                                    organic heterocyclic compound 18868
                                      heteroarene 17151
                                        monocyclic heteroarene 14980
                                          azole 14503
                                            conazole antifungal agent 6547
                                              conazole antifungal drug + 1609
                                              conazole fungicide + 5749
                                              diniconazole-M + 8
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