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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:rat metabolite
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Accession:CHEBI:86264 term browser browse the term
Definition:Any mammalian metabolite produced during a metabolic reaction in rat (Rattus norvegicus).
Synonyms:related_synonym: Rattus norvegicus metabolite;   Rattus norvegicus metabolites;   rat metabolites


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(R)-salsolinol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation EXP salsolinol results in decreased phosphorylation of AKT1 protein CTD PMID:23261589 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression EXP salsolinol results in increased expression of BAX protein CTD PMID:11502874 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression EXP salsolinol results in decreased expression of BCL2 protein CTD PMID:23261589 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression EXP salsolinol results in decreased expression of BCL2L1 protein CTD PMID:11502874 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479 		JBrowse link
G Bdnf brain-derived neurotrophic factor decreases expression EXP salsolinol results in decreased expression of BDNF protein CTD PMID:23261589 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
increases cleavage		 ISO
EXP		 salsolinol results in increased activity of CASP3 protein
Memantine inhibits the reaction [salsolinol results in increased activity of CASP3 protein]
salsolinol results in increased cleavage of CASP3 protein		 CTD PMID:17996985 PMID:23261589 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 decreases phosphorylation EXP salsolinol results in decreased phosphorylation of CREB1 protein CTD PMID:23261589 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Esr1 estrogen receptor 1 increases activity ISO salsolinol results in increased activity of ESR1 protein CTD PMID:24020587 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Gdnf glial cell derived neurotrophic factor decreases expression EXP salsolinol results in decreased expression of GDNF protein CTD PMID:23261589 NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases phosphorylation EXP salsolinol results in decreased phosphorylation of GSK3B protein CTD PMID:23261589 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Maoa monoamine oxidase A decreases activity ISO salsolinol results in decreased activity of MAOA protein CTD PMID:2296014 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases activity EXP salsolinol results in increased activity of MAPK8 protein CTD PMID:11502874 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
(S)-glaucine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases activity ISO glaucine results in increased activity of ABCB1 protein CTD PMID:23273999 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
2,3-epoxyphylloquinone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F9 coagulation factor IX multiple interactions ISO [VKORC1 protein results in increased reduction of vitamin K1 oxide] which results in increased carboxylation of and results in increased activity of F9 protein; [VKORC1L1 protein results in increased reduction of vitamin K1 oxide] which results in increased carboxylation of and results in increased activity of F9 protein CTD PMID:29581108 NCBI chr  X:138,352,334...138,396,835
Ensembl chr  X:138,352,298...138,396,835 		JBrowse link
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 multiple interactions
affects reduction
increases reduction		 ISO
EXP		 [VKORC1 protein results in increased reduction of vitamin K1 oxide] which results in increased carboxylation of and results in increased activity of F9 protein; coumachlor inhibits the reaction [VKORC1 protein results in increased reduction of vitamin K1 oxide]; fluindione inhibits the reaction [VKORC1 protein results in increased reduction of vitamin K1 oxide]; Warfarin inhibits the reaction [VKORC1 protein results in increased reduction of vitamin K1 oxide]
VKORC1 protein affects the reduction of vitamin K1 oxide
Warfarin inhibits the reaction [VKORC1 protein affects the reduction of vitamin K1 oxide]		 CTD PMID:23928358 PMID:29581108 NCBI chr 1:182,502,491...182,505,012
Ensembl chr 1:182,500,844...182,505,008 		JBrowse link
G Vkorc1l1 vitamin K epoxide reductase complex, subunit 1-like 1 multiple interactions
increases reduction
increases metabolic processing		 ISO
EXP		 [VKORC1L1 protein results in increased reduction of vitamin K1 oxide] which results in increased carboxylation of and results in increased activity of F9 protein; coumachlor inhibits the reaction [VKORC1L1 protein results in increased reduction of vitamin K1 oxide]; fluindione inhibits the reaction [VKORC1L1 protein results in increased reduction of vitamin K1 oxide]; Warfarin affects the reaction [VKORC1L1 protein results in increased reduction of vitamin K1 oxide]; Warfarin inhibits the reaction [VKORC1L1 protein results in increased metabolism of vitamin K1 oxide]; Warfarin inhibits the reaction [VKORC1L1 protein results in increased reduction of vitamin K1 oxide] CTD PMID:23710884 PMID:23928358 PMID:29581108 NCBI chr12:26,717,959...26,768,193
Ensembl chr12:26,623,976...26,768,225 		JBrowse link
4-methoxy-17beta-estradiol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases abundance
multiple interactions		 ISO CYP1B1 protein results in increased abundance of 4-methoxyestradiol
Tetrachlorodibenzodioxin promotes the reaction [CYP1B1 protein results in increased abundance of 4-methoxyestradiol]; Tetradecanoylphorbol Acetate promotes the reaction [Tetrachlorodibenzodioxin promotes the reaction [CYP1B1 protein results in increased abundance of 4-methoxyestradiol]]		 CTD PMID:9706865 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
4-methoxytyramine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Taar1 trace-amine-associated receptor 1 increases activity
multiple interactions		 ISO 3-hydroxy-4-methoxyphenethylamine results in increased activity of TAAR1 protein
[3-hydroxy-4-methoxyphenethylamine results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP		 CTD PMID:19725810 NCBI chr 1:21,517,742...21,518,740
Ensembl chr 1:21,517,258...21,532,084 		JBrowse link
5-methoxyindole-3-acetic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a8 solute carrier family 22 member 8 multiple interactions EXP 5-methoxyindoleacetic acid inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate] CTD PMID:10224140 NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450 		JBrowse link
8-epi-prostaglandin E2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptger4 prostaglandin E receptor 4 affects response to substance ISO PTGER4 protein affects the susceptibility to 8-isoprostaglandin E2 CTD PMID:22565502 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670 		JBrowse link
Ac-Asp-Glu term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Folh1 folate hydrolase 1 affects binding
multiple interactions		 ISO isospaglumic acid binds to FOLH1 protein
[2-(3-(1,3-dicarboxypropyl)ureido)pentanedioic acid binds to Aminocaproic Acid binds to 1-(1,3-carboxypropyl)-4,7-carboxymethyl-1,4,7-triazacyclononane binds to Valerates binds to bombesin (7-14) binds to Copper] inhibits the reaction [isospaglumic acid binds to FOLH1 protein]		 CTD PMID:24508213 NCBI chr 1:140,428,101...140,501,563
Ensembl chr 1:140,428,101...140,501,379 		JBrowse link
benzoylhypaconine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
increases transport		 ISO [Cyclosporine results in decreased activity of ABCB1 protein] which results in decreased transport of benzoylhypaconine; [Verapamil results in decreased activity of ABCB1 protein] which results in decreased transport of benzoylhypaconine
ABCB1 protein results in increased transport of benzoylhypaconine		 CTD PMID:23200901 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions ISO [verlukast results in decreased activity of ABCC2 protein] which results in decreased transport of benzoylhypaconine CTD PMID:23200901 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions ISO [3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester results in decreased activity of ABCG2 protein] which results in decreased transport of benzoylhypaconine CTD PMID:23200901 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409 		JBrowse link
dioleoyl phosphatidic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plek pleckstrin multiple interactions ISO dioleoylphosphatidic acid analog promotes the reaction [Guanosine 5'-O-(3-Thiotriphosphate) results in increased phosphorylation of PLEK protein] CTD PMID:8928743 NCBI chr14:91,397,015...91,429,693
Ensembl chr14:91,397,019...91,454,131 		JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO [1,2-oleoylphosphatidylcholine co-treated with dioleoylphosphatidic acid] binds to SOD1 protein; [1,2-oleoylphosphatidylcholine co-treated with dioleoylphosphatidic acid] binds to SOD1 protein mutant form; [1,2-oleoylphosphatidylcholine co-treated with dioleoylphosphatidic acid] promotes the reaction [SOD1 protein binds to SOD1 protein]; [1,2-oleoylphosphatidylcholine co-treated with dioleoylphosphatidic acid] promotes the reaction [SOD1 protein mutant form binds to SOD1 protein mutant form] CTD PMID:29649360 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
diphenylmethanol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr1 estrogen receptor 1 multiple interactions ISO benzohydrol binds to and results in increased activity of ESR1 protein CTD PMID:16079615 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO benzohydrol binds to and results in increased activity of ESR2 protein CTD PMID:16079615 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
epyrifenacil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppox protoporphyrinogen oxidase decreases activity EXP
ISO		 epyrifenacil metabolite results in decreased activity of PPOX protein; epyrifenacil results in decreased activity of PPOX protein CTD PMID:34908893 NCBI chr13:83,697,661...83,701,998
Ensembl chr13:83,664,891...83,701,805 		JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 increases uptake
multiple interactions		 EXP
ISO		 SLCO1A4 protein results in increased uptake of epyrifenacil metabolite
Digoxin inhibits the reaction [SLCO1A4 protein results in increased uptake of epyrifenacil metabolite]; Rifampin inhibits the reaction [SLCO1A4 protein results in increased uptake of epyrifenacil metabolite]; rifamycin SV inhibits the reaction [SLCO1A4 protein results in increased uptake of epyrifenacil metabolite]		 CTD PMID:34619012 NCBI chr 4:174,710,004...174,764,810
Ensembl chr 4:174,710,004...175,254,573 		JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 increases uptake
multiple interactions		 ISO
EXP		 SLCO1B2 protein results in increased uptake of epyrifenacil metabolite
SLCO1B3 protein results in increased uptake of epyrifenacil metabolite
Rifampin inhibits the reaction [SLCO1B3 protein results in increased uptake of epyrifenacil metabolite]; rifamycin SV inhibits the reaction [SLCO1B3 protein results in increased uptake of epyrifenacil metabolite]
Rifampin inhibits the reaction [SLCO1B2 protein results in increased uptake of epyrifenacil metabolite]; rifamycin SV inhibits the reaction [SLCO1B2 protein results in increased uptake of epyrifenacil metabolite]		 CTD PMID:34619012 NCBI chr 4:174,551,463...174,619,988
Ensembl chr 4:174,551,480...174,619,981 		JBrowse link
erucamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pgr progesterone receptor multiple interactions ISO erucyl amide binds to and results in decreased activity of PGR protein CTD PMID:27633901 NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344 		JBrowse link
Formyl-N-acetyl-5-methoxykynurenamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mapt microtubule-associated protein tau multiple interactions EXP N-acetyl-N-formyl-5-methoxykynurenamine inhibits the reaction [Streptozocin results in increased phosphorylation of MAPT protein] CTD PMID:31833155 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129 		JBrowse link
hepoxilin A3 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 increases export ISO ABCC2 protein results in increased export of 8-hydroxy-11,12-epoxyeicosa-5,9,14-trienoic acid CTD PMID:30102254 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
L-homoarginine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slco4c1 solute carrier organic anion transporter family, member 4C1 increases export ISO SLCO4C1 protein results in increased export of Homoarginine CTD PMID:30865704 NCBI chr 9:97,177,497...97,229,161
Ensembl chr 9:97,178,861...97,229,715 		JBrowse link
Leu-enkephalin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dpp3 dipeptidylpeptidase 3 increases cleavage
multiple interactions		 ISO DPP3 protein results in increased cleavage of Enkephalin, Leucine
spinorphin inhibits the reaction [DPP3 protein results in increased cleavage of Enkephalin, Leucine]; tynorphin inhibits the reaction [DPP3 protein results in increased cleavage of Enkephalin, Leucine]		 CTD PMID:10873616 NCBI chr 1:202,204,683...202,228,501
Ensembl chr 1:202,204,693...202,228,541 		JBrowse link
G Oprd1 opioid receptor, delta 1 increases activity ISO Enkephalin, Leucine results in increased activity of OPRD1 protein CTD PMID:26476280 NCBI chr 5:144,306,188...144,340,960
Ensembl chr 5:144,306,188...144,340,960 		JBrowse link
G Oprm1 opioid receptor, mu 1 increases activity ISO Enkephalin, Leucine results in increased activity of OPRM1 protein CTD PMID:26476280 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409 		JBrowse link
leukotriene B5 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ltb4r2 leukotriene B4 receptor 2 affects binding ISO leukotriene B5 binds to LTB4R2 protein CTD PMID:11006272 NCBI chr15:29,258,712...29,260,531
Ensembl chr15:29,259,240...29,260,316 		JBrowse link
N-(2,6-diethylphenyl)-2-chloroacetamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases chemical synthesis
multiple interactions
increases abundance		 ISO CYP3A4 protein results in increased chemical synthesis of 2-chloro-N-(2,6-diethylphenyl)acetamide
[CYP3A4 protein results in increased metabolism of alachlor] which results in increased abundance of 2-chloro-N-(2,6-diethylphenyl)acetamide
CYP3A4 protein results in increased abundance of 2-chloro-N-(2,6-diethylphenyl)acetamide		 CTD PMID:10475613 PMID:18273908 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
N-hydroxy-PhIP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO [ABCB1A protein affects the metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased abundance of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine CTD PMID:30701287 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcb1b ATP-binding cassette, sub-family B member 1B multiple interactions ISO [ABCB1B protein affects the metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased abundance of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine CTD PMID:30701287 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions ISO [ABCC2 protein affects the metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased abundance of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine CTD PMID:30701287 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 multiple interactions ISO [ABCC3 protein affects the metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased abundance of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine CTD PMID:30701287 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 affects transport
multiple interactions		 ISO ABCG2 protein affects the transport of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine
[ABCG2 protein affects the metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased abundance of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine		 CTD PMID:18322075 PMID:30701287 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO [CYP1A1 protein results in increased hydroxylation of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased chemical synthesis of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine; [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein] which results in increased chemical synthesis of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine
[[CYP1A2 protein co-treated with CYP1A1 protein] results in increased hydroxylation of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased chemical synthesis of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine; [CYP1A1 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased chemical synthesis of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine		 CTD PMID:16167840 PMID:17052995 PMID:17279779 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO [[CYP1A2 protein co-treated with CYP1A1 protein] results in increased hydroxylation of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased chemical synthesis of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine; [CYP1A2 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased chemical synthesis of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine; [CYP1A2 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased chemical synthesis of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine metabolite
[CYP1A2 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased abundance of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine		 CTD PMID:1943715 PMID:16167840 PMID:17279779 PMID:20192249 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO [CYP1B1 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased chemical synthesis of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine CTD PMID:17279779 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 multiple interactions ISO [CYP2C19 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased chemical synthesis of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine CTD PMID:17279779 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
decreases activity		 ISO 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine inhibits the reaction [Estradiol results in increased activity of ESR1 protein]
2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased activity of ESR1 protein		 CTD PMID:16533016 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Gsta1 glutathione S-transferase alpha 1 increases expression EXP 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of GSTA1 protein CTD PMID:17122891 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121 		JBrowse link
G Gsta3 glutathione S-transferase alpha 3 increases expression EXP 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of GSTA3 protein CTD PMID:17122891 NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240 		JBrowse link
G Gsta4 glutathione S-transferase alpha 4 increases expression EXP 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of GSTA4 protein CTD PMID:17122891 NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression EXP 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of GSTM1 protein CTD PMID:17122891 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions
increases expression
decreases response to substance		 ISO
EXP		 [GSTP1 protein co-treated with Glutathione] inhibits the reaction [[Adenosine Triphosphate results in increased metabolism of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased abundance of 2-amino-1-methyl-6-phenolimidazo(4,5-b)pyridine-DNA adduct]; [GSTP1 protein co-treated with Glutathione] inhibits the reaction [Adenosine Triphosphate results in increased activity of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine]
2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of GSTP1 protein
GSTP1 protein results in decreased susceptibility to 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine		 CTD PMID:11196146 PMID:17122891 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Nat1 N-acetyltransferase 1 multiple interactions
increases metabolic processing		 ISO NAT1 protein affects the acetylation of and affects the activity of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine
NAT1 protein results in increased metabolism of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine		 CTD PMID:11505221 PMID:29596660 NCBI chr16:22,218,217...22,238,516
Ensembl chr16:22,208,194...22,238,520 		JBrowse link
G Nat2 N-acetyltransferase 2 multiple interactions
increases metabolic processing
increases acetylation		 EXP
ISO		 4-biphenylamine inhibits the reaction [NAT2 protein results in increased acetylation of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine]
NAT2 protein results in increased metabolism of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine		 CTD PMID:12222688 PMID:18842621 PMID:29596660 NCBI chr16:22,207,362...22,238,513
Ensembl chr16:22,208,194...22,238,520 		JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 affects expression
multiple interactions		 EXP 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine affects the expression of PDIA3 protein
[2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Dihydrotestosterone] affects the expression of PDIA3 protein		 CTD PMID:19639176 NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236 		JBrowse link
G Rab7a RAB7A, member RAS oncogene family affects expression
multiple interactions		 EXP 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine affects the expression of RAB7A protein
[2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Dihydrotestosterone] affects the expression of RAB7A protein		 CTD PMID:19639176 NCBI chr 4:120,461,966...120,510,756
Ensembl chr 4:120,461,963...120,506,889 		JBrowse link
G Rps7 ribosomal protein S7 multiple interactions
affects expression		 EXP [2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Dihydrotestosterone] affects the expression of RPS7 protein
2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine affects the expression of RPS7 protein		 CTD PMID:19639176 NCBI chr 6:45,266,200...45,271,064
Ensembl chr 6:45,223,980...45,271,145
Ensembl chr 5:45,223,980...45,271,145 		JBrowse link
G Sar1a secretion associated, Ras related GTPase 1A affects expression
multiple interactions		 EXP 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine affects the expression of SAR1A protein
[2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Dihydrotestosterone] affects the expression of SAR1A protein		 CTD PMID:19639176 NCBI chr20:29,623,529...29,635,935
Ensembl chr20:29,623,553...29,635,935 		JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 multiple interactions
increases metabolic processing		 ISO SULT1A1 protein results in increased metabolism of and results in increased activity of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine
SULT1A1 protein results in increased metabolism of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine		 CTD PMID:12067565 PMID:29596660 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562 		JBrowse link
G Tp53 tumor protein p53 increases mutagenesis ISO 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased mutagenesis of TP53 protein CTD PMID:33189884 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 multiple interactions
affects metabolic processing
increases metabolic processing
increases glucuronidation		 ISO UGT1A1 promoter polymorphism affects the reaction [2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine binds to Glucuronides]; UGT1A1 protein promotes the reaction [2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine binds to Glucuronides]; UGT1A1 protein results in increased glucuronidation of and results in decreased activity of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine
UGT1A1 promoter polymorphism affects the metabolism of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine
UGT1A1 protein results in increased metabolism of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine
UGT1A1 protein results in increased glucuronidation of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine		 CTD PMID:11442279 PMID:15310245 PMID:15769885 PMID:15986396 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 increases glucuronidation ISO UGT1A3 protein results in increased glucuronidation of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine CTD PMID:15310245 NCBI chr 9:88,791,216...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a5 UDP glucuronosyltransferase family 1 member A5 increases metabolic processing
multiple interactions
increases glucuronidation		 ISO UGT1A4 protein results in increased metabolism of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine
UGT1A4 protein promotes the reaction [2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine binds to Glucuronides]
UGT1A4 protein results in increased glucuronidation of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine		 CTD PMID:15310245 PMID:15986396 NCBI chr 9:88,762,250...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 multiple interactions
increases metabolic processing
increases glucuronidation		 ISO UGT1A9 protein promotes the reaction [2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine binds to Glucuronides]
UGT1A9 protein results in increased metabolism of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine
UGT1A9 protein results in increased glucuronidation of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine		 CTD PMID:11375903 PMID:15310245 PMID:15986396 NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
N-nitroso-N-methyl-4-aminobutyric acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G H2ax H2A.X variant histone multiple interactions ISO [CYP2A6 protein results in increased metabolism of 4-(N-nitroso-N-methylamino)butyric acid] which results in increased expression of H2AX protein CTD PMID:35882637 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
Ensembl chr 4:44,671,786...44,673,239 		JBrowse link
nociceptin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Oprl1 opioid related nociceptin receptor 1 multiple interactions
affects binding		 ISO Endocannabinoids inhibits the reaction [Nociceptin binds to and results in increased activity of OPRL1 protein]; Nociceptin binds to and results in increased activity of OPRL1 protein
Nociceptin binds to OPRL1 protein		 CTD PMID:20359694 PMID:21866885 PMID:30102254 NCBI chr 3:168,831,934...168,839,920
Ensembl chr 3:168,834,003...168,839,920 		JBrowse link
resolvin D2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO resolvin D2 inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL2 protein] CTD PMID:21724996 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO resolvin D2 inhibits the reaction [Dextran Sulfate results in increased expression of CXCL2 protein] CTD PMID:21724996 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions ISO resolvin D2 inhibits the reaction [Dextran Sulfate results in increased expression of CXCL1 protein] CTD PMID:21724996 NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO resolvin D2 inhibits the reaction [Dextran Sulfate results in increased expression of ICAM1 mRNA] CTD PMID:21724996 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Ifng interferon gamma multiple interactions ISO resolvin D2 inhibits the reaction [Lipopolysaccharides results in increased secretion of IFNG protein] CTD PMID:21724996 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO resolvin D2 inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein] CTD PMID:21724996 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO resolvin D2 inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] CTD PMID:21724996 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Itgal integrin subunit alpha L multiple interactions ISO resolvin D2 inhibits the reaction [Dextran Sulfate results in increased expression of ITGAL mRNA] CTD PMID:21724996 NCBI chr 1:181,918,183...181,955,735
Ensembl chr 1:181,918,183...181,955,732 		JBrowse link
G Mpo myeloperoxidase multiple interactions ISO resolvin D2 inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; resolvin D2 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] CTD PMID:21724996 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO resolvin D2 inhibits the reaction [Dextran Sulfate results in increased expression of NFKBIA mRNA] CTD PMID:21724996 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO resolvin D2 inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] CTD PMID:21724996 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO resolvin D2 inhibits the reaction [Dextran Sulfate results in increased activity of RELA protein] CTD PMID:21724996 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO resolvin D2 inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; resolvin D2 inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] CTD PMID:21724996 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO resolvin D2 inhibits the reaction [Dextran Sulfate results in increased expression of VCAM1 mRNA] CTD PMID:21724996 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958 		JBrowse link
tauro-beta-muricholic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 increases expression
multiple interactions		 EXP tauromuricholic acid results in increased expression of ABCB11 protein
tauromuricholic acid results in increased expression of and results in increased activity of ABCB11 protein		 CTD PMID:11672435 PMID:12644037 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression
multiple interactions		 EXP tauromuricholic acid results in increased expression of ABCC2 protein
tauromuricholic acid results in increased expression of and results in increased activity of ABCC2 protein		 CTD PMID:11672435 PMID:12644037 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression EXP tauromuricholic acid results in increased expression of ABCC3 protein CTD PMID:11672435 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595 		JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
increases abundance
increases secretion		 ISO AHR gene mutant form inhibits the reaction [Tetrachlorodibenzodioxin affects the secretion of tauromuricholic acid]
AHR gene mutant form results in increased abundance of tauromuricholic acid
AHR gene mutant form results in increased secretion of tauromuricholic acid		 CTD PMID:29452137 PMID:32679164 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO [Taurocholic Acid co-treated with muricholic acid co-treated with tauromuricholic acid] results in increased expression of CXCL2 mRNA CTD PMID:22098667 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions ISO [Taurocholic Acid co-treated with muricholic acid co-treated with tauromuricholic acid] results in increased expression of CXCL1 mRNA CTD PMID:22098667 NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511 		JBrowse link
G Fech ferrochelatase affects abundance ISO FECH protein affects the abundance of tauromuricholic acid CTD PMID:29906468 NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO [Taurocholic Acid co-treated with muricholic acid co-treated with tauromuricholic acid] results in increased expression of ICAM1 mRNA CTD PMID:22098667 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Il10 interleukin 10 increases abundance ISO IL10 gene mutant form results in increased abundance of tauromuricholic acid CTD PMID:27580383 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 affects abundance ISO NR1H4 protein affects the abundance of tauromuricholic acid CTD PMID:30556042 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions
increases abundance		 ISO [PPARA gene mutant form results in increased susceptibility to Clofibrate] which results in increased abundance of tauromuricholic acid; PPARA gene mutant form inhibits the reaction [Gemfibrozil results in increased abundance of tauromuricholic acid]
PPARA gene mutant form results in increased abundance of tauromuricholic acid		 CTD PMID:24385052 PMID:29175453 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Slc10a2 solute carrier family 10 member 2 increases expression EXP tauromuricholic acid results in increased expression of SLC10A2 protein CTD PMID:11672435 NCBI chr16:84,386,528...84,409,475
Ensembl chr16:84,374,862...84,409,475 		JBrowse link
G Smad3 SMAD family member 3 increases abundance ISO SMAD3 protein results in increased abundance of tauromuricholic acid CTD PMID:23034213 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19874
    role 19844
      biological role 19842
        biochemical role 19549
          metabolite 19537
            eukaryotic metabolite 19362
              animal metabolite 19230
                mammalian metabolite 19229
                  rat metabolite 83
                    (11R,12S)-EET 0
                    (20S,23)-dihydroxyvitamin D3 0
                    (20S,23,24)-trihydroxyvitamin D3 0
                    (20S,23,25)-trihydroxyvitamin D3 0
                    (2E,5E)-tetradecadienoyl-CoA 0
                    (2E,6E)-farnesyl monophosphate 0
                    (4E,7E,10E,13E,16E)-docosapentaenoylcarnitine 0
                    (4E,7E,10E,13E,16E,19E)-docosahexaenoylcarnitine 0
                    (5E)-tetradecenoyl-CoA 0
                    (5E)-tetradecenoyl-L-carnitine 0
                    (5S,15S)-dihydroperoxy-(6E,8Z,11Z,13E)-icosatetraenoic acid 0
                    (8R,9S)-EET 0
                    (8S,9R)-EET 0
                    (R)-salsolinol + 12
                    (S)-glaucine + 1
                    (Z)-icos-13-enoic acid 0
                    1,2,3,4-tetrahydro-beta-carboline-3-carboxylic acid 0
                    1,2-bis(octadec-9-enoyl)phosphatidic acid + 2
                    1,2-ditetradecanoyl-3-(6-sulfoquinovopyranosyl)glycerol 0
                    1-(2,3-dihydro-1H-pyrrolizin-5-yl)-2-propen-1-one 0
                    1-O-(5,6-epoxyretinoyl)-beta-D-glucuronic acid 0
                    1-docosanoyl-2-pentadecanoyl-sn-glycero-3-phosphoethanolamine 0
                    1-docosanoyl-2-tetradecanoyl-sn-glycero-3-phosphoethanolamine 0
                    1-hexadecanoyl-2-icosanoyl-sn-glycero-3-phosphoethanolamine 0
                    1-icosanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine 0
                    1-icosanoyl-2-tetradecanoyl-sn-glycero-3-phosphocholine 0
                    1-methylhypoxanthine 0
                    1-octadecanoyl-2-pentadecanoyl-sn-glycero-3-phosphocholine 0
                    1-pentadecanoyl-2-docosanoyl-sn-glycero-3-phosphoethanolamine 0
                    1-pentadecanoyl-2-octadecanoyl-sn-glycero-3-phosphocholine 0
                    1-pentadecanoyl-sn-glycero-3-phosphocholine 0
                    1-tetradecanoyl-2-docosanoyl-sn-glycero-3-phosphoethanolamine 0
                    10-HETE 0
                    11 hydroxy-(14R,15S)-epoxy-(5Z,8Z,12E)-icosatrienoic acid 0
                    11-HEPE + 0
                    11beta-PGE2 0
                    12(S)-HEPE 0
                    13,14-dihydroprostaglandin F2alpha 0
                    13-HETE + 0
                    16-hydroxytriptolide 0
                    19-hydroxyleukotriene B4 0
                    2,3,4,5-tetranor-thromboxane B1 0
                    2,3,4-trihydroxbenzophenone 0
                    2,3-dinor-TXB1 0
                    2,3-epoxymenatetrenone 0
                    2,3-epoxyphylloquinone 3
                    2,4-dihydroxyacetophenone-5-O-sulfate 0
                    2,4-dimethylbenzyl alcohol 0
                    2-(acetoxyamino)-3-methylimidazo[4,5-f]quinoline 0
                    2-exo-hydroxy-1,4-cineole 0
                    2-methylpropane-1,2-diol 0
                    23-acetoxysoladulcidine 0
                    2beta-hydroxytestosterone 0
                    3,4-dihydro-4-[(5-methyl-2-furanyl)methylene]-2H-pyrrole 0
                    3,4-epoxy-1-cyclohexene + 0
                    3-(5-hydroxyindol-3-yl)pyruvic acid 0
                    3-(5-methylfurfuryl)pyrrole 0
                    3-dehydro-2-deoxyecdysone 0
                    3-flavene 0
                    3-hydroxy-2,2-dimethylbutyric acid 0
                    3alpha,17alpha-dihydroxy-5alpha-pregnan-20-one 0
                    4'-O-methyl-(-)-epicatechin 0
                    4-(2-amino-3-hydroxyphenyl)-2,4-dioxobutanoic acid 0
                    4-O-methyl-L-dopa 0
                    4-bromophenol 0
                    4-heptanone 0
                    4-hydroxynonanal 0
                    4-methoxy-17beta-estradiol + 1
                    4-methoxytyramine 1
                    5(S),15(S)-DiHETE 0
                    5(S),15(S)-DiHETE(1-) 0
                    5,6-epoxyretinoic acid + 0
                    5,7-icosanedione 0
                    5-hydroxybenzimidazole 0
                    5-hydroxyindoleacetylglycine 0
                    5-methoxyindole-3-acetic acid 1
                    5-methyldihydrofolic acid 0
                    5-methylfuran-2-carboxylic acid 0
                    6,8-icosanedione 0
                    7-HETE 0
                    7alpha-hydroxydehydroepiandrosterone 0
                    7alpha-hydroxypregnenolone 0
                    8-epi-prostaglandin E2 1
                    9-cis-retinoyl-beta-D-glucuronide 0
                    Asp-Tyr-Met-Gly-Trp-Met-Asp-Phe-NH2 0
                    Formyl-N-acetyl-5-methoxykynurenamine 1
                    HMBOA beta-D-glucoside 0
                    L-homoarginine 1
                    L-lyxonic acid 0
                    Leu-enkephalin 3
                    N-(2,6-diethylphenyl)-2-chloroacetamide 1
                    N-[(11Z)-octadecenoyl]sphinganine-1-phosphocholine 0
                    N-[(15Z)-tetracosenoyl]sphingosine 1-phosphate 0
                    N-acetyl-L-aspartate(2-) + 0
                    N-acetyl-L-aspartic acid + 1
                    N-acetyl-S-benzyl-L-cysteine 0
                    N-acetylneuraminlactose sulfate 0
                    N-carbamoylglycine + 0
                    N-ethyldiethanolamine 0
                    N-hydroxy-MeIQx 0
                    N-hydroxy-PhIP 27
                    N-methylnorsalsolinol 0
                    N-nitroso-N-methyl-4-aminobutyric acid 1
                    N-oleoylsphinganine-1-phosphocholine 0
                    N-pentacosanoylsphingosine 0
                    O-heptadecanoylcarnitine 0
                    O-pentadecanoylcarnitine 0
                    S-(5-acetamido-2-hydroxyphenyl)-N-acetyl-L-cysteine 0
                    S-3100-CA + 3
                    S-adenosylmethioninamine 0
                    S-propyl propanethiosulfinate 0
                    Tyr-Met 0
                    [des-Phe(8), des-Arg(9)]-bradykinin 0
                    all-trans-retinyl dodecanoate 0
                    allocholic acid + 0
                    allodeoxycholic acid + 0
                    alpha-D-galactosyl-(1->4)-beta-D-galactosyl-N-(pentacosanoyl)sphingosine 0
                    alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-Gal-(1->3)-beta-GalNAc-(1->4)-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer 0
                    alpha-Neup5Ac-(2->3)-beta-D-Galp-(1->3)-beta-D-GalpNAc-(1->4)-[alpha-Neup5Ac-(2->8)-alpha-Neup5Ac-(2->8)-alpha-Neup5Ac-(2->3)]-beta-D-Galp-(1->4)-beta-D-Glcp-(1<->1')-Cer + 0
                    angiotensin (1-9) 0
                    angiotensin (1-9) dizwitterion 0
                    artemoin A 0
                    artemoin B 0
                    artemoin C 0
                    artemoin D 0
                    asparagoside F 0
                    benzoylhypaconine 3
                    beta-(methylenecyclopropyl)pyruvic acid 0
                    beta-D-galactosyl-(1->4)-beta-D-galactosyl-N-(pentacosanoyl)sphingosine 0
                    beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer 0
                    cohibin C 0
                    cohibin D 0
                    columbianadin 0
                    cotinine N-oxide 0
                    crosatoside B 0
                    cyclodopa 5-beta-D-glucoside 0
                    cystathionine ketimine 0
                    desmethylranitidine 0
                    dihydroisorhamnetin + 0
                    diphenylmethanol + 2
                    egonol beta-D-glucoside 0
                    epietiocholanolone 0
                    erucamide 1
                    ferulic acid 4-sulfate 0
                    guanidinoacetic acid 0
                    hepoxilin A3 + 1
                    heptan-4-ol 0
                    hyocholate 0
                    hyocholic acid + 0
                    hypothiocyanous acid 0
                    isolithocholic acid 0
                    leucomethylene blue 0
                    leukotriene B5 1
                    leukotriene C3 0
                    leukotriene D3 0
                    lithocholic acid 3-O-(beta-D-glucuronide) 0
                    lugdunin 0
                    monoisodecyl phthalate 0
                    monopentyl phthalate 0
                    nociceptin 1
                    nodakenetin + 0
                    nonan-2-ol + 0
                    nonan-3-ol 0
                    nonan-4-ol 0
                    oleyl acetate 0
                    p-tolyl beta-D-glucuronide 0
                    p-tolyl beta-D-glucuronide(1-) 0
                    pelargonidin 3-O-sophoroside 0
                    phosphatidylethanolamine 36:2 + 0
                    phosphatidylethanolamine 37:2 + 0
                    phosphatidylethanolamine 38:3 + 0
                    phosphatidylethanolamine 38:4 + 0
                    pivaloyl-CoA 0
                    propyl propionate 0
                    prostaglandin B3 0
                    resolvin D2 14
                    resolvin E2 0
                    riddelliine N-oxide 0
                    saikogenin E + 0
                    somatostatin-28 0
                    tauro-beta-muricholate 0
                    tauro-beta-muricholic acid 13
                    tauroursocholate 0
                    tauroursocholic acid 0
                    thiamine(1+) carboxylic acid 0
                    thiamine(1+) triphosphate 0
                    tridodecylamine 0
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