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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:psorospermin
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Accession:CHEBI:8617 term browser browse the term
Definition:An organic heterotetracyclic compound that is 1,2-dihydro-6H-furo[2,3-c]xanthene substituted by a hydroxy group at position 10, a methoxy group at position 5 nad a 2-methyloxiran-2-yl group at position 2.
Synonyms:exact_synonym: (2R)-10-hydroxy-5-methoxy-2-[(2R)-2-methyloxiran-2-yl]-1,2-dihydro-6H-furo[2,3-c]xanthen-6-one
 related_synonym: Formula=C19H16O6;   InChI=1S/C19H16O6/c1-19(8-23-19)14-6-10-12(24-14)7-13(22-2)15-16(21)9-4-3-5-11(20)17(9)25-18(10)15/h3-5,7,14,20H,6,8H2,1-2H3/t14-,19-/m1/s1;   InChIKey=BBNDPXOGORGETN-AUUYWEPGSA-N;   SMILES=COc1cc2O[C@H](Cc2c2oc3c(O)cccc3c(=O)c12)[C@@]1(C)CO1
 xref: CAS:74045-97-9;   KEGG:C10090;   KNApSAcK:C00002972
 xref_mesh: MESH:C025543
 xref: PMID:7189773;   PMID:8205539;   Patent:EP1585740;   Patent:US2004102515;   Patent:US6933396;   Patent:WO2004019888;   Reaxys:5140143



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psorospermin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO psorospermin inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin] CTD PMID:7083125 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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  CHEBI ontology 19880
    role 19850
      application 19695
        pharmaceutical 19532
          drug 19532
            antineoplastic agent 17823
              psorospermin 1
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  CHEBI ontology 19880
    subatomic particle 19878
      composite particle 19878
        hadron 19878
          baryon 19878
            nucleon 19878
              atomic nucleus 19878
                atom 19878
                  main group element atom 19817
                    p-block element atom 19817
                      carbon group element atom 19757
                        carbon atom 19754
                          organic molecular entity 19754
                            organic molecule 19706
                              organic cyclic compound 19495
                                organic heterocyclic compound 18874
                                  organic heteromonocyclic compound 17795
                                    saturated organic heteromonocyclic parent 11304
                                      oxirane 11285
                                        epoxide 11284
                                          psorospermin 1
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