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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:amprolium(1+)
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Accession:CHEBI:85266 term browser browse the term
Definition:A pyridinium ion that is the cationic portion of amprolium, a veterinary drug which is used for prevention of coccidiosis in poultry and cattle.
Synonyms:exact_synonym: 1-[(4-amino-2-propylpyrimidin-5-yl)methyl]-2-methylpyridin-1-ium
 related_synonym: Formula=C14H19N4;   InChI=1S/C14H19N4/c1-3-6-13-16-9-12(14(15)17-13)10-18-8-5-4-7-11(18)2/h4-5,7-9H,3,6,10H2,1-2H3,(H2,15,16,17)/q+1;   InChIKey=IPZFPROOBOUEIG-UHFFFAOYSA-N;   SMILES=CCCc1ncc(C[n+]2ccccc2C)c(N)n1;   amprolium cation
 xref: LINCS:LSM-6688;   Reaxys:4149652



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amprolium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc19a3 solute carrier family 19 member 3 multiple interactions ISO Amprolium inhibits the reaction [SLC19A3 protein results in increased uptake of Metformin]; Amprolium inhibits the reaction [SLC19A3 protein results in increased uptake of Thiamine] CTD PMID:26528626 NCBI chr 9:84,275,722...84,299,368
Ensembl chr 9:84,277,024...84,299,337
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19867
    role 19837
      biological role 19835
        antimicrobial agent 18251
          antimicrobial drug 11184
            antiprotozoal drug 7448
              coccidiostat 76
                amprolium(1+) 1
                  amprolium 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19867
    subatomic particle 19865
      composite particle 19865
        hadron 19865
          baryon 19865
            nucleon 19865
              atomic nucleus 19865
                atom 19865
                  main group element atom 19803
                    p-block element atom 19803
                      p-block molecular entity 19803
                        carbon group molecular entity 19744
                          organic molecular entity 19740
                            organic ion 11442
                              organic cation 8951
                                pyridinium ion 2442
                                  amprolium(1+) 1
                                    amprolium 1
paths to the root