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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:EC 2.7.4.* (phosphotransferases with a phosphate group as acceptor) inhibitor
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Accession:CHEBI:84803 term browser browse the term
Definition:Any EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any phosphotransferase with a phosphate group as acceptor (EC 2.7.4.*).
Synonyms:related_synonym: EC 2.7.4.* (phosphotransferases with a phosphate group as acceptor) inhibitors;   EC 2.7.4.* inhibitor;   EC 2.7.4.* inhibitors


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ellagic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp3 acid phosphatase 3 increases expression ISO Ellagic Acid results in increased expression of ACP3 mRNA CTD PMID:12002526 NCBI chr 8:113,784,372...113,833,033
Ensembl chr 8:113,785,032...113,833,033 		JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant multiple interactions ISO Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of ACP5 mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of ACP5 protein] CTD PMID:32971123 NCBI chr 8:28,939,984...28,946,639
Ensembl chr 8:28,939,985...28,943,929 		JBrowse link
G Agt angiotensinogen multiple interactions EXP Ellagic Acid inhibits the reaction [AGT protein results in decreased abundance of NADP]; Ellagic Acid inhibits the reaction [AGT protein results in increased activity of CASP3 protein]; Ellagic Acid inhibits the reaction [AGT protein results in increased activity of RELA protein]; Ellagic Acid inhibits the reaction [AGT protein results in increased expression of AGTR1 protein]; Ellagic Acid inhibits the reaction [AGT protein results in increased expression of CYBA mRNA]; Ellagic Acid inhibits the reaction [AGT protein results in increased expression of MYH7 mRNA]; Ellagic Acid inhibits the reaction [AGT protein results in increased expression of NCF2 mRNA]; Ellagic Acid inhibits the reaction [AGT protein results in increased expression of NOS2 mRNA]; Ellagic Acid inhibits the reaction [AGT protein results in increased expression of NPPA mRNA]; Ellagic Acid inhibits the reaction [AGT protein results in increased expression of NPPB mRNA]; Ellagic Acid inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein]; Ellagic Acid inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein] CTD PMID:38356441 NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a multiple interactions EXP Ellagic Acid inhibits the reaction [AGT protein results in increased expression of AGTR1 protein] CTD PMID:38356441 NCBI chr17:34,383,397...34,435,523
Ensembl chr17:34,381,467...34,435,660 		JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 increases expression ISO Ellagic Acid results in increased expression of AIFM1 protein CTD PMID:23554011 NCBI chr  X:132,528,107...132,567,237
Ensembl chr  X:132,528,107...132,567,237 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation
multiple interactions 		ISO
EXP 		Ellagic Acid results in increased phosphorylation of AKT1 protein
Ellagic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of AKT1 protein] 		CTD PMID:26986492 PMID:35236242 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Alb albumin multiple interactions
affects binding 		ISO ALB protein promotes the reaction [Ellagic Acid results in increased activity of F12 protein]
Ellagic Acid binds to ALB protein 		CTD PMID:6343536 PMID:25247703 NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865 		JBrowse link
G Alkbh2 alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase decreases activity ISO Ellagic Acid results in decreased activity of ALKBH2 protein CTD PMID:31088072 NCBI chr12:48,156,825...48,161,489
Ensembl chr12:48,156,827...48,161,483 		JBrowse link
G Alpl alkaline phosphatase, biomineralization associated increases expression ISO Ellagic Acid results in increased expression of ALPL mRNA CTD PMID:38145796 NCBI chr 5:155,234,770...155,289,785
Ensembl chr 5:155,234,775...155,254,167 		JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 decreases expression
increases expression 		ISO Ellagic Acid results in decreased expression of APAF1 mRNA
Ellagic Acid results in increased expression of APAF1 mRNA 		CTD PMID:12002526 PMID:35179410 NCBI chr 7:27,381,392...27,466,772
Ensembl chr 7:27,381,855...27,466,772 		JBrowse link
G App amyloid beta precursor protein multiple interactions EXP Ellagic Acid inhibits the reaction [Aluminum Chloride results in increased expression of APP protein] CTD PMID:34944019 NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971 		JBrowse link
G Ascl1 achaete-scute family bHLH transcription factor 1 increases expression ISO Ellagic Acid results in increased expression of ASCL1 mRNA CTD PMID:12002526 NCBI chr 7:23,790,642...23,793,509
Ensembl chr 7:23,790,360...23,798,231 		JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression ISO Ellagic Acid results in increased expression of ASNS mRNA CTD PMID:12002526 NCBI chr 4:36,752,061...36,769,970
Ensembl chr 4:36,751,802...36,776,050 		JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO Ellagic Acid results in increased expression of ATF3 mRNA CTD PMID:12002526 NCBI chr13:105,274,103...105,331,653
Ensembl chr13:105,282,440...105,295,750 		JBrowse link
G Atg5 autophagy related 5 increases expression ISO Ellagic Acid results in increased expression of ATG5 mRNA CTD PMID:12002526 NCBI chr20:49,380,835...49,471,826
Ensembl chr20:49,380,813...49,471,821 		JBrowse link
G Bad BCL2-associated agonist of cell death increases expression ISO Ellagic Acid results in increased expression of BAD protein CTD PMID:23554011 NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:213,562,187...213,572,034 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression 		EXP
ISO 		Ellagic Acid inhibits the reaction [sodium arsenate results in increased expression of BAX mRNA]
Ellagic Acid results in increased expression of BAX mRNA 		CTD PMID:29854611 PMID:35179410 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression
multiple interactions
decreases expression 		ISO
EXP 		Ellagic Acid results in increased expression of BCL2 protein
[Ellagic Acid co-treated with resveratrol] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of BCL2 mRNA]
Ellagic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of BCL2 protein]; Ellagic Acid inhibits the reaction [sodium arsenate results in decreased expression of BCL2 mRNA]
Ellagic Acid results in decreased expression of BCL2 mRNA 		CTD PMID:20103723 PMID:22386815 PMID:29854611 PMID:35179410 PMID:35236242 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Bmp6 bone morphogenetic protein 6 decreases expression ISO Ellagic Acid results in decreased expression of BMP6 mRNA CTD PMID:12002526 NCBI chr17:26,523,704...26,785,558
Ensembl chr17:26,523,704...26,675,261 		JBrowse link
G Brf1 BRF1 general transcription factor IIIB subunit decreases expression ISO Ellagic Acid results in decreased expression of BRF1 mRNA CTD PMID:12002526 NCBI chr 6:137,854,055...137,902,629
Ensembl chr 6:137,855,449...137,902,386 		JBrowse link
G Calr calreticulin decreases expression ISO Ellagic Acid results in decreased expression of CALR mRNA CTD PMID:12002526 NCBI chr19:40,213,367...40,218,262
Ensembl chr19:40,213,239...40,219,236 		JBrowse link
G Casp3 caspase 3 increases expression
decreases expression
decreases activity
increases activity
multiple interactions 		ISO
EXP 		Ellagic Acid results in increased expression of CASP3 mRNA
Ellagic Acid results in decreased expression of CASP3 mRNA
Ellagic Acid results in decreased activity of CASP3 protein
Ellagic Acid results in increased activity of CASP3 protein
Ellagic Acid results in increased expression of and results in increased activity of CASP3 protein
Ellagic Acid inhibits the reaction [AGT protein results in increased activity of CASP3 protein]; Ellagic Acid inhibits the reaction [Aluminum Chloride results in increased expression of CASP3 protein]; Ellagic Acid inhibits the reaction [Carbon Tetrachloride results in decreased expression of CASP3 protein]; Ellagic Acid inhibits the reaction [Doxorubicin results in increased expression of CASP3 protein]; Ellagic Acid inhibits the reaction [sodium arsenate results in increased activity of CASP3 protein]; Ellagic Acid inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; Ellagic Acid promotes the reaction [sinapinic acid inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]]; sinapinic acid promotes the reaction [Ellagic Acid inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]] 		CTD PMID:12002526 PMID:22386815 PMID:23554011 PMID:23811531 PMID:28815802 More... NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp9 caspase 9 multiple interactions ISO Ellagic Acid results in increased expression of and results in increased activity of CASP9 protein CTD PMID:23554011 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Cat catalase increases activity
multiple interactions 		EXP Ellagic Acid results in increased activity of CAT protein
Ellagic Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein]; Ellagic Acid inhibits the reaction [Carbon Tetrachloride results in decreased activity of CAT protein]; Ellagic Acid inhibits the reaction [chromium hexavalent ion results in decreased activity of CAT protein]; Ellagic Acid inhibits the reaction [sodium arsenite results in decreased activity of CAT protein] 		CTD PMID:20074268 PMID:24877639 PMID:29864931 PMID:35236242 PMID:36108929 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases secretion ISO Ellagic Acid results in decreased secretion of CCL2 protein CTD PMID:20816778 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875 		JBrowse link
G Ccng1 cyclin G1 decreases expression EXP ellagic acid inhibits the reaction [estrogen increases expression of Ccng1 mRNA and protein in rat mammary tissue] RGD PMID:23791885 RGD:151356928 NCBI chr10:25,678,503...25,684,876
Ensembl chr10:25,677,885...25,683,766 		JBrowse link
G Cd14 CD14 molecule decreases expression ISO Ellagic Acid results in decreased expression of CD14 mRNA CTD PMID:20816778 NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,608,883...28,611,292 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression ISO Ellagic Acid results in decreased expression of CDK1 protein CTD PMID:23554011 NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,265,289...19,280,455 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression 		ISO [resveratrol co-treated with Ellagic Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CDKN1A mRNA]
Ellagic Acid results in increased expression of CDKN1A protein
[Ellagic Acid co-treated with Quercetin] results in increased expression of CDKN1A mRNA; Ellagic Acid promotes the reaction [Quercetin results in increased expression of CDKN1A protein]; pifithrin inhibits the reaction [Ellagic Acid promotes the reaction [Quercetin results in increased expression of CDKN1A protein]] 		CTD PMID:15735102 PMID:20103723 PMID:23554011 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969 		JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression ISO Ellagic Acid results in increased expression of COL1A1 mRNA; Ellagic Acid results in increased expression of COL1A1 protein CTD PMID:38145796 NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460 		JBrowse link
G Ctsd cathepsin D multiple interactions EXP Ellagic Acid inhibits the reaction [Isoproterenol results in increased activity of CTSD protein] CTD PMID:21762681 NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:206,956,944...206,968,821 		JBrowse link
G Ctsk cathepsin K multiple interactions ISO Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of CTSK mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of CTSK protein] CTD PMID:32971123 NCBI chr 2:185,747,548...185,758,512
Ensembl chr 2:185,747,165...185,765,582 		JBrowse link
G Cyba cytochrome b-245 alpha chain multiple interactions EXP Ellagic Acid inhibits the reaction [AGT protein results in increased expression of CYBA mRNA] CTD PMID:38356441 NCBI chr19:67,396,143...67,404,214
Ensembl chr19:67,396,143...67,404,214 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases expression
decreases activity 		ISO Ellagic Acid results in decreased expression of CYP1A1 mRNA
Ellagic Acid results in decreased activity of CYP1A1 protein 		CTD PMID:19329757 PMID:20816778 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity
multiple interactions 		ISO Ellagic Acid results in decreased activity of CYP1B1 protein
[Ellagic Acid co-treated with Plant Extracts] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]; [Ellagic Acid co-treated with resveratrol] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA] 		CTD PMID:19329757 PMID:20103723 NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142 		JBrowse link
G Daxx death-domain associated protein decreases expression ISO Ellagic Acid results in decreased expression of DAXX mRNA CTD PMID:12002526 NCBI chr20:4,971,973...4,978,062
Ensembl chr20:4,971,941...4,977,720 		JBrowse link
G Dffa DNA fragmentation factor subunit alpha decreases expression ISO Ellagic Acid results in decreased expression of DFFA mRNA CTD PMID:12002526 NCBI chr 5:164,823,807...164,836,729
Ensembl chr 5:164,823,807...164,836,728 		JBrowse link
G E4f1 E4F transcription factor 1 increases expression ISO Ellagic Acid results in increased expression of E4F1 mRNA CTD PMID:12002526 NCBI chr10:13,978,975...13,999,646
Ensembl chr10:13,978,990...13,990,506 		JBrowse link
G Egr3 early growth response 3 decreases expression ISO Ellagic Acid results in decreased expression of EGR3 mRNA CTD PMID:12002526 NCBI chr15:51,560,482...51,565,778
Ensembl chr15:51,560,344...51,565,712 		JBrowse link
G Endog endonuclease G increases expression ISO Ellagic Acid results in increased expression of ENDOG protein CTD PMID:23554011 NCBI chr 3:33,846,935...33,849,531
Ensembl chr 3:33,846,885...33,849,573 		JBrowse link
G Ep300 E1A binding protein p300 increases expression ISO Ellagic Acid results in increased expression of EP300 mRNA CTD PMID:12002526 NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:114,946,982...115,058,574 		JBrowse link
G Eps15 epidermal growth factor receptor pathway substrate 15 increases expression ISO Ellagic Acid results in increased expression of EPS15 mRNA CTD PMID:12002526 NCBI chr 5:129,274,487...129,374,856
Ensembl chr 5:129,274,502...129,374,856 		JBrowse link
G Ezh1 enhancer of zeste 1 polycomb repressive complex 2 subunit increases expression ISO Ellagic Acid results in increased expression of EZH1 mRNA CTD PMID:12002526 NCBI chr10:86,626,307...86,662,257
Ensembl chr10:86,626,308...86,652,620 		JBrowse link
G F12 coagulation factor XII multiple interactions
increases activity 		ISO ALB protein promotes the reaction [Ellagic Acid results in increased activity of F12 protein] CTD PMID:6343536 NCBI chr17:9,212,819...9,220,664
Ensembl chr17:9,212,819...9,220,664 		JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 decreases expression ISO Ellagic Acid results in decreased expression of FGFR1 mRNA CTD PMID:12002526 NCBI chr16:73,194,631...73,249,855
Ensembl chr16:73,194,631...73,249,855 		JBrowse link
G Flna filamin A decreases expression ISO Ellagic Acid results in decreased expression of FLNA mRNA CTD PMID:12002526 NCBI chr  X:157,159,051...157,185,559
Ensembl chr  X:157,159,051...157,182,343 		JBrowse link
G Fn1 fibronectin 1 multiple interactions EXP Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein] CTD PMID:24877639 NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Ellagic Acid co-treated with Plant Extracts] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of FOS mRNA]; [Ellagic Acid co-treated with Resveratrol] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of FOS mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of FOS mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of FOS protein] CTD PMID:20103723 PMID:32971123 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase decreases activity ISO Ellagic Acid results in decreased activity of G6PD protein CTD PMID:25130191 NCBI chr  X:157,352,364...157,372,144
Ensembl chr  X:157,352,373...157,372,144 		JBrowse link
G Gal galanin and GMAP prepropeptide multiple interactions EXP Ellagic Acid inhibits the reaction [phosalone results in increased activity of GAL protein] CTD PMID:27965107 NCBI chr 1:210,079,709...210,084,572
Ensembl chr 1:210,079,702...210,084,229 		JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 decreases expression ISO Ellagic Acid results in decreased expression of GPLD1 mRNA CTD PMID:12002526 NCBI chr17:40,512,659...40,560,483
Ensembl chr17:40,512,660...40,554,975 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP
ISO 		Ellagic Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GPT protein]; Ellagic Acid inhibits the reaction [sodium arsenite results in increased expression of GPT protein]
Ellagic Acid inhibits the reaction [Diquat results in increased activity of GPT protein] 		CTD PMID:24877639 PMID:29935397 PMID:35268077 NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160 		JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions EXP
ISO 		Ellagic Acid inhibits the reaction [sodium arsenite results in decreased expression of GPX1 mRNA]
Ellagic Acid inhibits the reaction [Diquat results in decreased expression of GPX1 mRNA] 		CTD PMID:29935397 PMID:35268077 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581 		JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP Ellagic Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of GSR protein] CTD PMID:24877639 NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394 		JBrowse link
G Gsta4 glutathione S-transferase alpha 4 increases expression ISO Ellagic Acid results in increased expression of GSTA4 mRNA CTD PMID:12002526 NCBI chr 8:87,947,247...87,964,490
Ensembl chr 8:87,930,566...87,964,488 		JBrowse link
G Gstt1 glutathione S-transferase theta 1 affects expression EXP Ellagic Acid affects the expression of GSTT1 protein CTD PMID:9855024 NCBI chr20:12,856,068...12,873,020
Ensembl chr20:12,856,083...12,873,019 		JBrowse link
G Gtf2e2 general transcription factor IIE subunit 2 increases expression ISO Ellagic Acid results in increased expression of GTF2E2 mRNA CTD PMID:12002526 NCBI chr16:65,102,386...65,152,563
Ensembl chr16:65,102,390...65,161,394 		JBrowse link
G Gtf2h4 general transcription factor 2H subunit 4 increases expression ISO Ellagic Acid results in increased expression of GTF2H4 mRNA CTD PMID:12002526 NCBI chr20:3,076,110...3,081,805
Ensembl chr20:3,076,088...3,081,760 		JBrowse link
G Gusb glucuronidase, beta multiple interactions EXP Ellagic Acid inhibits the reaction [Isoproterenol results in increased activity of GUSB protein] CTD PMID:21762681 NCBI chr12:32,337,281...32,350,838
Ensembl chr12:32,334,075...32,363,024 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha decreases expression ISO Ellagic Acid results in decreased expression of HIF1A mRNA CTD PMID:12002526 NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323 		JBrowse link
G Hlcs holocarboxylase synthetase decreases activity ISO Ellagic Acid results in decreased activity of HLCS protein CTD PMID:26303405 NCBI chr11:46,925,491...47,123,111
Ensembl chr11:46,925,491...47,105,082 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions 		ISO Ellagic Acid results in increased expression of HMOX1 mRNA; Ellagic Acid results in increased expression of HMOX1 protein
[Paraquat co-treated with Ellagic Acid] results in increased expression of HMOX1 mRNA; [Paraquat co-treated with Ellagic Acid] results in increased expression of HMOX1 protein
Ellagic Acid inhibits the reaction [Diquat results in decreased expression of HMOX1 mRNA] 		CTD PMID:22386815 PMID:23546295 PMID:35268077 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818 		JBrowse link
G Hras HRas proto-oncogene, GTPase multiple interactions ISO [Ellagic Acid co-treated with Plant Extracts] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased mutagenesis of HRAS gene]; [Ellagic Acid co-treated with resveratrol] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased mutagenesis of HRAS gene] CTD PMID:20103723 NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:205,725,975...205,729,590 		JBrowse link
G Ier2 immediate early response 2 increases expression ISO Ellagic Acid results in increased expression of IER2 mRNA CTD PMID:12002526 NCBI chr19:40,399,373...40,400,897
Ensembl chr19:40,398,160...40,402,708 		JBrowse link
G Ifng interferon gamma multiple interactions EXP Ellagic Acid inhibits the reaction [sodium arsenate results in increased expression of IFNG mRNA]; Ellagic Acid inhibits the reaction [sodium arsenate results in increased expression of IFNG protein] CTD PMID:29854611 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216 		JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 increases expression ISO Ellagic Acid results in increased expression of IGFBP2 mRNA CTD PMID:12002526 NCBI chr 9:81,864,811...81,892,179
Ensembl chr 9:81,864,783...81,892,171 		JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 decreases expression ISO Ellagic Acid results in decreased expression of IGFBP4 mRNA CTD PMID:12002526 NCBI chr10:84,491,471...84,503,487
Ensembl chr10:84,485,775...84,503,473 		JBrowse link
G Il1b interleukin 1 beta decreases expression
multiple interactions 		ISO
EXP 		Ellagic Acid results in decreased expression of IL1B mRNA
Ellagic Acid inhibits the reaction [IL1B protein results in increased secretion of CXCL8 protein]
Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B protein]; Ellagic Acid inhibits the reaction [Glucose results in increased expression of IL1B protein]; Ellagic Acid inhibits the reaction [Isoproterenol results in increased expression of IL1B mRNA]; Ellagic Acid inhibits the reaction [phosalone results in increased expression of IL1B protein]; Ellagic Acid inhibits the reaction [sodium arsenate results in increased expression of IL1B mRNA]; Ellagic Acid inhibits the reaction [sodium arsenite results in increased expression of IL1B protein] 		CTD PMID:18377686 PMID:20816778 PMID:21762681 PMID:24877639 PMID:27965107 More... NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il1r1 interleukin 1 receptor type 1 decreases expression ISO Ellagic Acid results in decreased expression of IL1R1 mRNA CTD PMID:20816778 NCBI chr 9:50,000,558...50,076,579
Ensembl chr 9:50,000,566...50,076,579 		JBrowse link
G Il6 interleukin 6 multiple interactions EXP Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL6 protein]; Ellagic Acid inhibits the reaction [Glucose results in increased expression of IL6 protein]; Ellagic Acid inhibits the reaction [Isoproterenol results in increased expression of IL6 mRNA]; Ellagic Acid inhibits the reaction [phosalone results in increased expression of IL6 protein] CTD PMID:21762681 PMID:24877639 PMID:27965107 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D increases expression ISO Ellagic Acid results in increased expression of INPP5D mRNA CTD PMID:12002526 NCBI chr 9:95,735,533...95,840,584
Ensembl chr 9:95,735,530...95,840,589 		JBrowse link
G Iqgap2 IQ motif containing GTPase activating protein 2 increases expression ISO Ellagic Acid results in increased expression of IQGAP2 mRNA CTD PMID:12002526 NCBI chr 2:28,629,558...28,904,649
Ensembl chr 2:28,629,558...28,904,649 		JBrowse link
G Irf9 interferon regulatory factor 9 increases expression ISO Ellagic Acid results in increased expression of IRF9 mRNA CTD PMID:12002526 NCBI chr15:33,065,422...33,071,881
Ensembl chr15:33,065,659...33,071,879 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit decreases expression ISO Ellagic Acid results in decreased expression of JUN mRNA; Ellagic Acid results in decreased expression of JUN protein modified form CTD PMID:23811531 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285 		JBrowse link
G Klk1c10 kallikrein 1-related peptidase C10 decreases expression ISO Ellagic Acid results in decreased expression of KLK3 mRNA CTD PMID:12002526 NCBI chr 1:103,539,527...103,543,586
Ensembl chr 1:103,539,527...103,543,586 		JBrowse link
G Litaf lipopolysaccharide-induced TNF factor increases expression ISO Ellagic Acid results in increased expression of LITAF mRNA CTD PMID:12002526 NCBI chr10:5,163,258...5,199,930
Ensembl chr10:5,163,242...5,199,930 		JBrowse link
G Map1a microtubule-associated protein 1A decreases expression ISO Ellagic Acid results in decreased expression of MAP1A mRNA CTD PMID:12002526 NCBI chr 3:128,716,907...128,736,638
Ensembl chr 3:128,716,940...128,740,159 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 decreases expression ISO Ellagic Acid results in decreased expression of MAP3K1 mRNA; Ellagic Acid results in decreased expression of MAP3K1 protein CTD PMID:23811531 NCBI chr 2:45,081,889...45,150,555
Ensembl chr 2:45,081,889...45,149,897 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO
EXP 		Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased phosphorylation of MAPK1 protein]
Ellagic Acid inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein] 		CTD PMID:32971123 PMID:38356441 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk11 mitogen-activated protein kinase 11 increases expression ISO Ellagic Acid results in increased expression of MAPK11 mRNA CTD PMID:23811531 NCBI chr 7:122,098,120...122,105,023
Ensembl chr 7:122,098,121...122,105,038 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions EXP Ellagic Acid inhibits the reaction [phosalone results in increased expression of MAPK14 protein] CTD PMID:27965107 NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO
EXP 		Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased phosphorylation of MAPK3 protein]
Ellagic Acid inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein] 		CTD PMID:32971123 PMID:38356441 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO [Ellagic Acid co-treated with Quercetin] results in increased phosphorylation of MAPK8 protein CTD PMID:15735102 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions ISO [Ellagic Acid co-treated with Quercetin] results in increased phosphorylation of MAPK9 protein CTD PMID:15735102 NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,670,756...34,712,228 		JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 decreases activity EXP Ellagic Acid results in decreased activity of MGST1 protein CTD PMID:16125204 NCBI chr 4:172,760,930...172,776,157
Ensembl chr 4:172,760,886...172,776,875 		JBrowse link
G Mir140 microRNA 140 multiple interactions EXP ellagic acid inhibits the reaction [hypoxia and acute myocardial infarction decreases expression of mir140 RNA in cardiac muscle cells] RGD PMID:28922712 RGD:329347824 NCBI chr19:52,375,293...52,375,391
Ensembl chr19:52,375,293...52,375,391 		JBrowse link
G Mmd monocyte to macrophage differentiation-associated increases expression ISO Ellagic Acid results in increased expression of MMD mRNA CTD PMID:12002526 NCBI chr10:75,570,366...75,598,610
Ensembl chr10:75,570,397...75,598,609 		JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
decreases activity
decreases expression 		ISO Ellagic Acid results in decreased activity of and results in decreased secretion of MMP2 protein; zinc chloride inhibits the reaction [Ellagic Acid results in decreased activity of and results in decreased secretion of MMP2 protein]
Ellagic Acid results in decreased activity of MMP2 protein
Ellagic Acid results in decreased expression of MMP2 mRNA 		CTD PMID:21573219 PMID:35179410 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856 		JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression
decreases activity 		ISO Ellagic Acid results in decreased expression of MMP9 mRNA
Ellagic Acid results in decreased activity of MMP9 protein 		CTD PMID:35179410 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442 		JBrowse link
G Myh7 myosin heavy chain 7 multiple interactions EXP Ellagic Acid inhibits the reaction [AGT protein results in increased expression of MYH7 mRNA] CTD PMID:38356441 NCBI chr15:32,416,525...32,439,851
Ensembl chr15:32,416,527...32,438,194 		JBrowse link
G Ncf2 neutrophil cytosolic factor 2 multiple interactions EXP Ellagic Acid inhibits the reaction [AGT protein results in increased expression of NCF2 mRNA] CTD PMID:38356441 NCBI chr13:67,505,492...67,536,015
Ensembl chr13:67,505,375...67,536,149 		JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 multiple interactions ISO Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 protein] CTD PMID:32971123 NCBI chr18:76,321,386...76,430,997
Ensembl chr18:76,321,386...76,430,990 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 affects localization
affects response to substance
increases expression
multiple interactions 		ISO
EXP 		Ellagic Acid affects the localization of NFE2L2 protein
NFE2L2 protein affects the susceptibility to Ellagic Acid
Ellagic Acid results in increased expression of NFE2L2 mRNA; Ellagic Acid results in increased expression of NFE2L2 protein
[Paraquat co-treated with Ellagic Acid] results in increased expression of and affects the localization of NFE2L2 protein; [Paraquat co-treated with Ellagic Acid] results in increased expression of NFE2L2 mRNA; Ellagic Acid results in increased expression of and affects the localization of NFE2L2 protein
[Ellagic Acid co-treated with Diquat] results in increased expression of NFE2L2 mRNA; Ellagic Acid inhibits the reaction [Diquat results in decreased expression of NFE2L2 mRNA]; Ellagic Acid inhibits the reaction [sodium arsenate results in decreased expression of NFE2L2 mRNA]
Ellagic Acid inhibits the reaction [Carbon Tetrachloride results in decreased expression of NFE2L2 protein] 		CTD PMID:22386815 PMID:23546295 PMID:30503583 PMID:35236242 PMID:35268077 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090 		JBrowse link
G Nfkb2 nuclear factor kappa B subunit 2 decreases expression ISO Ellagic Acid results in decreased expression of NFKB2 mRNA CTD PMID:12002526 PMID:35179410 NCBI chr 1:255,106,010...255,114,649
Ensembl chr 1:255,107,374...255,114,637 		JBrowse link
G Nnat neuronatin increases expression ISO Ellagic Acid results in increased expression of NNAT mRNA CTD PMID:12002526 NCBI chr 3:166,646,373...166,648,845
Ensembl chr 3:166,646,384...166,649,086 		JBrowse link
G Nop56 NOP56 ribonucleoprotein decreases expression ISO Ellagic Acid results in decreased expression of NOP56 mRNA CTD PMID:12002526 NCBI chr 3:137,926,187...137,934,971
Ensembl chr 3:137,929,646...137,934,959 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
decreases expression 		EXP
ISO 		Ellagic Acid inhibits the reaction [AGT protein results in increased expression of NOS2 mRNA]; Ellagic Acid inhibits the reaction [Doxorubicin results in increased expression of NOS2 protein]
Ellagic Acid results in decreased expression of NOS2 mRNA 		CTD PMID:28815802 PMID:35179410 PMID:38356441 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880 		JBrowse link
G Npas2 neuronal PAS domain protein 2 increases expression ISO Ellagic Acid results in increased expression of NPAS2 mRNA CTD PMID:12002526 NCBI chr 9:48,959,225...49,138,036
Ensembl chr 9:48,959,148...49,138,037 		JBrowse link
G Nppa natriuretic peptide A multiple interactions EXP Ellagic Acid inhibits the reaction [AGT protein results in increased expression of NPPA mRNA] CTD PMID:38356441 NCBI chr 5:163,712,184...163,713,493
Ensembl chr 5:163,712,184...163,713,493 		JBrowse link
G Nppb natriuretic peptide B multiple interactions EXP Ellagic Acid inhibits the reaction [AGT protein results in increased expression of NPPB mRNA] CTD PMID:38356441 NCBI chr 5:163,699,955...163,701,314
Ensembl chr 5:163,699,839...163,701,310 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression
multiple interactions 		ISO Ellagic Acid results in increased expression of NQO1 mRNA; Ellagic Acid results in increased expression of NQO1 protein
[Paraquat co-treated with Ellagic Acid] results in increased expression of NQO1 mRNA; [Paraquat co-treated with Ellagic Acid] results in increased expression of NQO1 protein
Ellagic Acid inhibits the reaction [Diquat results in decreased expression of NQO1 mRNA] 		CTD PMID:23546295 PMID:35268077 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO Ellagic Acid results in increased activity of NR1I3 protein CTD PMID:21821919 NCBI chr13:86,165,327...86,170,362
Ensembl chr13:86,165,349...86,170,370 		JBrowse link
G Parg poly (ADP-ribose) glycohydrolase decreases activity ISO Ellagic Acid results in decreased activity of PARG protein CTD PMID:19840838 NCBI chr16:7,442,696...7,550,585
Ensembl chr16:7,442,726...7,550,584 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions EXP Ellagic Acid inhibits the reaction [Rotenone results in increased cleavage of PARP1 protein] CTD PMID:25247703 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567 		JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO [resveratrol co-treated with Ellagic Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of PCNA mRNA] CTD PMID:20103723 NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901 		JBrowse link
G Pdia2 protein disulfide isomerase family A, member 2 multiple interactions EXP Ellagic Acid inhibits the reaction [Rotenone results in increased nitrosation of and results in decreased activity of PDIA2 protein] CTD PMID:25247703 NCBI chr10:15,720,301...15,723,386
Ensembl chr10:15,720,301...15,723,396 		JBrowse link
G Pgd phosphogluconate dehydrogenase decreases activity ISO Ellagic Acid results in decreased activity of PGD protein CTD PMID:25130191 NCBI chr 5:164,865,830...164,882,029
Ensembl chr 5:164,865,830...164,882,029 		JBrowse link
G Pla2g2a phospholipase A2 group IIA decreases expression ISO Ellagic Acid results in decreased expression of PLA2G2A mRNA CTD PMID:20816778 NCBI chr 5:156,359,725...156,362,302
Ensembl chr 5:156,359,725...156,362,297 		JBrowse link
G Plp2 proteolipid protein 2 increases expression ISO Ellagic Acid results in increased expression of PLP2 mRNA CTD PMID:12002526 NCBI chr  X:17,506,153...17,509,552
Ensembl chr  X:17,506,059...17,509,550 		JBrowse link
G Pml PML nuclear body scaffold decreases expression ISO Ellagic Acid results in decreased expression of PML mRNA CTD PMID:12002526 NCBI chr 8:67,523,164...67,557,801
Ensembl chr 8:67,523,164...67,576,083 		JBrowse link
G Ppard peroxisome proliferator-activated receptor delta decreases expression ISO Ellagic Acid results in decreased expression of PPARD mRNA CTD PMID:12002526 NCBI chr20:6,300,527...6,365,707
Ensembl chr20:6,352,183...6,365,707 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression ISO Ellagic Acid results in increased expression of PPARG protein CTD PMID:23811531 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions
decreases expression 		ISO Ellagic Acid inhibits the reaction [sodium arsenate results in increased expression of PPARGC1A mRNA]
Ellagic Acid results in decreased expression of PPARGC1A mRNA 		CTD PMID:30503583 NCBI chr14:63,073,505...63,729,215
Ensembl chr14:63,273,189...63,729,213 		JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 decreases expression ISO Ellagic Acid results in decreased expression of PRKG1 mRNA CTD PMID:12002526 NCBI chr 1:237,818,950...239,052,184
Ensembl chr 1:237,823,053...239,103,005 		JBrowse link
G Ptn pleiotrophin decreases expression
increases expression 		ISO Ellagic Acid results in decreased expression of PTN mRNA
Ellagic Acid results in increased expression of PTN mRNA 		CTD PMID:12002526 NCBI chr 4:66,260,764...66,342,614
Ensembl chr 4:66,260,764...66,342,482 		JBrowse link
G Ptprn2 protein tyrosine phosphatase, receptor type N2 increases expression ISO Ellagic Acid results in increased expression of PTPRN2 mRNA CTD PMID:12002526 NCBI chr 6:143,582,568...144,334,573
Ensembl chr 6:143,582,547...144,336,744 		JBrowse link
G Ran RAN, member RAS oncogene family decreases expression ISO Ellagic Acid results in decreased expression of RAN mRNA CTD PMID:12002526 NCBI chr12:33,311,155...33,314,339
Ensembl chr12:33,311,158...33,314,317 		JBrowse link
G Rb1 RB transcriptional corepressor 1 multiple interactions EXP Ellagic Acid inhibits the reaction [phosalone results in increased expression of RB1 mRNA]; Ellagic Acid inhibits the reaction [phosalone results in increased expression of RB1 protein] CTD PMID:27965107 NCBI chr15:54,780,858...54,911,989
Ensembl chr15:54,780,858...54,911,857 		JBrowse link
G Reck reversion-inducing-cysteine-rich protein with kazal motifs increases expression
multiple interactions 		ISO Ellagic Acid results in increased expression of RECK mRNA; Ellagic Acid results in increased expression of RECK protein
zinc chloride inhibits the reaction [Ellagic Acid results in increased expression of RECK mRNA]; zinc chloride inhibits the reaction [Ellagic Acid results in increased expression of RECK protein] 		CTD PMID:21573219 NCBI chr 5:62,898,717...62,965,274
Ensembl chr 5:62,898,668...62,965,270 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit decreases expression
multiple interactions 		ISO
EXP 		Ellagic Acid results in decreased expression of RELA mRNA
Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of RELA protein]; Ellagic Acid inhibits the reaction [AGT protein results in increased activity of RELA protein]; Ellagic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of RELA protein]; Ellagic Acid inhibits the reaction [Glucose results in increased expression of RELA protein]; Ellagic Acid inhibits the reaction [phosalone results in increased expression of RELA protein]
Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased phosphorylation of RELA protein]
Ellagic Acid inhibits the reaction [TNF protein affects the localization of and results in increased activity of RELA protein] 		CTD PMID:12002526 PMID:24877639 PMID:27473819 PMID:27965107 PMID:32971123 More... NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
G Rgs5 regulator of G-protein signaling 5 decreases expression ISO Ellagic Acid results in decreased expression of RGS5 mRNA CTD PMID:12002526 NCBI chr13:84,381,077...84,417,875
Ensembl chr13:84,380,910...84,421,352 		JBrowse link
G Runx2 RUNX family transcription factor 2 increases expression ISO Ellagic Acid results in increased expression of RUNX2 mRNA; Ellagic Acid results in increased expression of RUNX2 protein CTD PMID:38145796 NCBI chr 9:23,661,278...23,990,248
Ensembl chr 9:23,664,952...23,990,027 		JBrowse link
G Scd stearoyl-CoA desaturase decreases expression ISO Ellagic Acid results in decreased expression of SCD mRNA CTD PMID:20816778 NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:253,218,970...253,231,785 		JBrowse link
G Septin2 septin 2 increases expression ISO Ellagic Acid results in increased expression of SEPTIN2 mRNA CTD PMID:12002526 NCBI chr 9:101,465,535...101,498,766
Ensembl chr 9:101,465,650...101,498,759 		JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions EXP Ellagic Acid inhibits the reaction [Aluminum Chloride results in decreased expression of SOD1 mRNA]; Ellagic Acid inhibits the reaction [Aluminum Chloride results in decreased expression of SOD1 protein] CTD PMID:34944019 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399 		JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions EXP Ellagic Acid inhibits the reaction [sodium arsenite results in decreased expression of SOD2 mRNA] CTD PMID:29935397 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168 		JBrowse link
G Sod3 superoxide dismutase 3 decreases expression ISO Ellagic Acid results in decreased expression of SOD3 mRNA CTD PMID:12002526 NCBI chr14:62,822,865...62,828,602
Ensembl chr14:62,811,177...62,829,125 		JBrowse link
G Sp7 Sp7 transcription factor increases expression ISO Ellagic Acid results in increased expression of SP7 mRNA; Ellagic Acid results in increased expression of SP7 protein CTD PMID:38145796 NCBI chr 7:135,363,193...135,373,376
Ensembl chr 7:135,363,199...135,373,559 		JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression ISO Ellagic Acid results in increased expression of SPP1 mRNA; Ellagic Acid results in increased expression of SPP1 protein CTD PMID:38145796 NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,613,576...5,619,820 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions ISO Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of SRC mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of SRC protein] CTD PMID:32971123 NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:166,511,985...166,559,462 		JBrowse link
G Star steroidogenic acute regulatory protein increases expression
multiple interactions 		ISO Ellagic Acid results in increased expression of STAR mRNA
Ellagic Acid inhibits the reaction [sodium arsenate results in decreased expression of STAR mRNA] 		CTD PMID:30503583 NCBI chr16:72,969,824...72,974,447
Ensembl chr16:72,961,518...72,974,447 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 increases expression
decreases expression 		ISO Ellagic Acid results in increased expression of STAT3 mRNA
Ellagic Acid results in decreased expression of STAT3 mRNA 		CTD PMID:12002526 PMID:20816778 NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359 		JBrowse link
G Taf1c TATA-box binding protein associated factor, RNA polymerase 1 subunit C decreases expression ISO Ellagic Acid results in decreased expression of TAF1C mRNA CTD PMID:12002526 NCBI chr19:64,561,079...64,567,599
Ensembl chr19:64,560,562...64,567,599 		JBrowse link
G Tcf12 transcription factor 12 increases expression ISO Ellagic Acid results in increased expression of TCF12 mRNA CTD PMID:12002526 NCBI chr 8:81,371,201...81,682,337
Ensembl chr 8:81,373,321...81,679,922 		JBrowse link
G Tert telomerase reverse transcriptase multiple interactions
increases expression 		ISO
EXP 		Ellagic Acid inhibits the reaction [Estradiol results in increased expression of TERT mRNA alternative form]
Ellagic Acid results in increased expression of TERT mRNA alternative form
Ellagic Acid inhibits the reaction [phosalone results in decreased activity of TERT protein] 		CTD PMID:19501078 PMID:27965107 NCBI chr 1:31,465,766...31,488,650
Ensembl chr 1:31,466,056...31,488,111 		JBrowse link
G Tfam transcription factor A, mitochondrial decreases expression ISO Ellagic Acid results in decreased expression of TFAM mRNA CTD PMID:12002526 NCBI chr20:17,355,373...17,367,422
Ensembl chr20:17,355,363...17,369,877 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression
multiple interactions 		ISO
EXP 		Ellagic Acid results in increased expression of TGFB1 mRNA
Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein] 		CTD PMID:12002526 PMID:24877639 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases expression 		EXP
ISO 		Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein]; Ellagic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein]; Ellagic Acid inhibits the reaction [chromium hexavalent ion results in increased expression of TNF protein]; Ellagic Acid inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; Ellagic Acid inhibits the reaction [Glucose results in increased expression of TNF protein]; Ellagic Acid inhibits the reaction [Isoproterenol results in increased expression of TNF mRNA]; Ellagic Acid inhibits the reaction [phosalone results in increased expression of TNF protein]; Ellagic Acid inhibits the reaction [sodium arsenate results in increased expression of TNF mRNA]; Ellagic Acid inhibits the reaction [sodium arsenate results in increased expression of TNF protein]; Ellagic Acid inhibits the reaction [sodium arsenite results in increased expression of TNF protein]
Ellagic Acid results in decreased expression of TNF mRNA
Ellagic Acid inhibits the reaction [TNF protein affects the localization of and results in increased activity of RELA protein]; Ellagic Acid inhibits the reaction [TNF protein results in increased activity of and affects the secretion of CXCL8 protein] 		CTD PMID:21762681 PMID:24877639 PMID:27473819 PMID:27965107 PMID:28815802 More... NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tnfrsf11a TNF receptor superfamily member 11A multiple interactions
affects binding 		ISO Ellagic Acid inhibits the reaction [TNFSF11 protein binds to TNFRSF11A protein]
Ellagic Acid binds to TNFRSF11A protein 		CTD PMID:32971123 NCBI chr13:22,442,930...22,501,257
Ensembl chr13:22,442,665...22,501,257 		JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions
affects binding 		ISO Ellagic Acid inhibits the reaction [TNFSF11 protein binds to TNFRSF11A protein]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of ACP5 mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of ACP5 protein]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of CTSK mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of CTSK protein]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of FOS mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of FOS protein]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 protein]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of SRC mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of SRC protein]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased phosphorylation of MAPK1 protein]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased phosphorylation of MAPK3 protein]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased phosphorylation of RELA protein]
Ellagic Acid binds to TNFSF11 protein 		CTD PMID:32971123 NCBI chr15:60,083,008...60,114,479
Ensembl chr15:60,083,008...60,114,479 		JBrowse link
G Tnnt2 troponin T2, cardiac type multiple interactions EXP Ellagic Acid inhibits the reaction [Isoproterenol results in increased expression of TNNT2 protein] CTD PMID:21762681 NCBI chr13:49,819,123...49,837,125
Ensembl chr13:49,822,304...49,837,125 		JBrowse link
G Tp53 tumor protein p53 increases expression
multiple interactions 		ISO
EXP 		Ellagic Acid results in increased expression of TP53 mRNA; Ellagic Acid results in increased expression of TP53 protein
Ellagic Acid inhibits the reaction [phosalone results in increased expression of TP53 mRNA]; Ellagic Acid inhibits the reaction [phosalone results in increased expression of TP53 protein]
Ellagic Acid promotes the reaction [Quercetin results in increased phosphorylation of TP53 protein]; pifithrin inhibits the reaction [Ellagic Acid promotes the reaction [Quercetin results in increased phosphorylation of TP53 protein]] 		CTD PMID:15735102 PMID:23554011 PMID:27965107 PMID:35179410 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Ugp2 UDP-glucose pyrophosphorylase 2 decreases expression ISO Ellagic Acid results in decreased expression of UGP2 mRNA CTD PMID:12002526 NCBI chr14:99,657,637...99,698,573
Ensembl chr14:99,657,639...99,698,002 		JBrowse link
G Usp4 ubiquitin specific peptidase 4 decreases expression ISO Ellagic Acid results in decreased expression of USP4 mRNA CTD PMID:12002526 NCBI chr 8:117,912,576...117,957,934
Ensembl chr 8:117,914,614...117,957,949 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions EXP Ellagic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of VEGFA protein] CTD PMID:35236242 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194 		JBrowse link
G Wars1 tryptophanyl-tRNA synthetase 1 increases expression ISO Ellagic Acid results in increased expression of WARS1 mRNA CTD PMID:12002526 NCBI chr 6:133,540,463...133,571,645
Ensembl chr 6:133,539,744...133,571,645 		JBrowse link
G Wee1 WEE1 G2 checkpoint kinase decreases expression ISO Ellagic Acid results in decreased expression of WEE1 protein CTD PMID:23554011 NCBI chr 1:173,605,609...173,632,450
Ensembl chr 1:173,608,949...173,632,449 		JBrowse link
G Zbtb16 zinc finger and BTB domain containing 16 decreases expression ISO Ellagic Acid results in decreased expression of ZBTB16 mRNA CTD PMID:12002526 NCBI chr 8:57,885,886...58,073,507
Ensembl chr 8:57,891,081...58,073,507 		JBrowse link
G Zmym2 zinc finger MYM-type containing 2 increases expression ISO Ellagic Acid results in increased expression of ZMYM2 mRNA CTD PMID:12002526 NCBI chr15:35,151,356...35,224,528
Ensembl chr15:35,127,994...35,224,941 		JBrowse link
Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 20874
    role 20844
      biological role 20831
        biochemical role 19888
          enzyme inhibitor 18710
            EC 2.* (transferase) inhibitor 14864
              EC 2.7.* (P-containing group transferase) inhibitor 14367
                EC 2.7.4.* (phosphotransferases with a phosphate group as acceptor) inhibitor 149
                  EC 2.7.4.6 (nucleoside-diphosphate kinase) inhibitor + 149
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