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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:N,N-dimethylacetamide
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Accession:CHEBI:84254 term browser browse the term
Definition:A member of the class of acetamides that is acetamide in which the hydrogens attached to the N atom have been replaced by two methyl groups respectively. Metabolite observed in cancer metabolism.
Synonyms:related_synonym: Formula=C4H9NO;   InChI=1S/C4H9NO/c1-4(6)5(2)3/h1-3H3;   InChIKey=FXHOOIRPVKKKFG-UHFFFAOYSA-N;   SMILES=CN(C)C(C)=O;   dimethylacetamide
 xref: CAS:127-19-5;   KEGG:C20339
 xref_mesh: MESH:C013959
 xref: PMID:25518943;   Reaxys:1737614;   Wikipedia:Dimethylacetamide


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N,N-dimethylacetamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase affects response to substance ISO CAT gene SNP affects the susceptibility to dimethylacetamide CTD PMID:28749186 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions ISO dimethylacetamide inhibits the reaction [Lipopolysaccharides results in increased secretion of CSF2 protein] CTD PMID:27782292 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199 		JBrowse link
G Il10 interleukin 10 multiple interactions ISO dimethylacetamide inhibits the reaction [Lipopolysaccharides results in increased secretion of IL10 protein] CTD PMID:27782292 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO dimethylacetamide inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
dimethylacetamide inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; dimethylacetamide inhibits the reaction [TNF protein results in increased secretion of IL6 protein]		 CTD PMID:27782292 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO dimethylacetamide inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein] CTD PMID:27782292 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO dimethylacetamide inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; dimethylacetamide inhibits the reaction [TNF protein results in increased secretion of IL6 protein] CTD PMID:27782292 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19922
    chemical entity 19920
      atom 19892
        nonmetal atom 19849
          nitrogen atom 19025
            nitrogen molecular entity 19025
              organonitrogen compound 18846
                carboxamide 17576
                  acetamides 14643
                    N,N-dimethylacetamide 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19922
    subatomic particle 19892
      composite particle 19892
        hadron 19920
          baryon 19892
            nucleon 19920
              atomic nucleus 19892
                atom 19892
                  main group element atom 19866
                    p-block element atom 19866
                      carbon group element atom 19805
                        carbon atom 19802
                          organic molecular entity 19775
                            heteroorganic entity 19556
                              organochalcogen compound 19315
                                organooxygen compound 19205
                                  carbon oxoacid 18694
                                    carboxylic acid 18691
                                      carboacyl group 17723
                                        univalent carboacyl group 17723
                                          carbamoyl group 17576
                                            carboxamide 17576
                                              acetamides 14643
                                                acetamide 8761
                                                  N,N-dimethylacetamide 6
paths to the root