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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:N,N-dimethylacetamide
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Accession:CHEBI:84254 term browser browse the term
Definition:A member of the class of acetamides that is acetamide in which the hydrogens attached to the N atom have been replaced by two methyl groups respectively. Metabolite observed in cancer metabolism.
Synonyms:related_synonym: Formula=C4H9NO;   InChI=1S/C4H9NO/c1-4(6)5(2)3/h1-3H3;   InChIKey=FXHOOIRPVKKKFG-UHFFFAOYSA-N;   SMILES=CN(C)C(C)=O;   dimethylacetamide
 xref: CAS:127-19-5;   KEGG:C20339
 xref_mesh: MESH:C013959
 xref: PMID:25518943;   Reaxys:1737614;   Wikipedia:Dimethylacetamide


show annotations for term's descendants           Sort by:
N,N-dimethylacetamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase affects response to substance ISO CAT gene SNP affects the susceptibility to dimethylacetamide CTD PMID:28749186 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526 		JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions ISO dimethylacetamide inhibits the reaction [Lipopolysaccharides results in increased secretion of CSF2 protein] CTD PMID:27782292 NCBI chr10:38,887,692...38,889,673
Ensembl chr10:38,887,692...38,890,031 		JBrowse link
G Il10 interleukin 10 multiple interactions ISO dimethylacetamide inhibits the reaction [Lipopolysaccharides results in increased secretion of IL10 protein] CTD PMID:27782292 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO dimethylacetamide inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
dimethylacetamide inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; dimethylacetamide inhibits the reaction [TNF protein results in increased secretion of IL6 protein] 		CTD PMID:27782292 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO dimethylacetamide inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein] CTD PMID:27782292 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO dimethylacetamide inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; dimethylacetamide inhibits the reaction [TNF protein results in increased secretion of IL6 protein] CTD PMID:27782292 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20862
    chemical entity 20860
      atom 20860
        nonmetal atom 20766
          nitrogen atom 19595
            nitrogen molecular entity 19595
              organonitrogen compound 19403
                carboxamide 17921
                  acetamides 14869
                    N,N-dimethylacetamide 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 20862
    subatomic particle 20860
      composite particle 20860
        hadron 20860
          baryon 20860
            nucleon 20860
              atomic nucleus 20860
                atom 20860
                  main group element atom 20781
                    p-block element atom 20781
                      carbon group element atom 20715
                        carbon atom 20710
                          organic molecular entity 20710
                            heteroorganic entity 20219
                              organochalcogen compound 19904
                                organooxygen compound 19806
                                  carbon oxoacid 19155
                                    carboxylic acid 19152
                                      carboacyl group 18085
                                        univalent carboacyl group 18085
                                          carbamoyl group 17921
                                            carboxamide 17921
                                              acetamides 14869
                                                acetamide 8919
                                                  N,N-dimethylacetamide 6
paths to the root