CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol
Accession: CHEBI:83779
browse the term
Definition: A tertiary alcohol that is pentan-3-ol substituted by a 4-chlorophenyl, methyl, methyl, and a 1H-1,2,4-triazol-1-ylmethyl at positions 1, 4, 4 and 3 respectively.
Synonyms: related_synonym: Formula=C16H22ClN3O; InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3; InChIKey=PXMNMQRDXWABCY-UHFFFAOYSA-N; SMILES=CC(C)(C)C(O)(CCc1ccc(Cl)cc1)Cn1cncn1
xref: PPDB:610
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A2ml1
alpha-2-macroglobulin-like 1
decreases expression
ISO
tebuconazole results in decreased expression of OVOS2 mRNA
CTD
PMID:30458266
NCBI chr 4:161,815,111...161,857,286
Ensembl chr 4:161,814,708...161,857,343
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Abcb11
ATP binding cassette subfamily B member 11
multiple interactions decreases activity
ISO
tebuconazole promotes the reaction [propiconazole results in decreased expression of ABCB11 mRNA] tebuconazole results in decreased activity of ABCB11 protein
CTD
PMID:36291160
NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
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Abcc3
ATP binding cassette subfamily C member 3
decreases expression
ISO
tebuconazole results in decreased expression of ABCC3 mRNA
CTD
PMID:36291160
NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
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Abcg1
ATP binding cassette subfamily G member 1
decreases expression
ISO
tebuconazole results in decreased expression of ABCG1 mRNA
CTD
PMID:30458266
NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
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Abcg5
ATP binding cassette subfamily G member 5
decreases expression
ISO
tebuconazole results in decreased expression of ABCG5 mRNA
CTD
PMID:30458266 PMID:36291160
NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563
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Abo
ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase
decreases expression
ISO
tebuconazole results in decreased expression of ABO mRNA
CTD
PMID:30458266
NCBI chr 3:10,162,087...10,182,835
Ensembl chr 3:10,162,096...10,191,423
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Acat2
acetyl-CoA acetyltransferase 2
increases expression
ISO
tebuconazole results in increased expression of ACAT2 mRNA
CTD
PMID:36291160
NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821
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Acer2
alkaline ceramidase 2
decreases expression
ISO
tebuconazole results in decreased expression of ACER2 mRNA
CTD
PMID:30458266
NCBI chr 5:101,391,830...101,442,615
Ensembl chr 5:101,391,885...101,442,614
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Acot11
acyl-CoA thioesterase 11
decreases expression
ISO
tebuconazole results in decreased expression of ACOT11 mRNA
CTD
PMID:30458266
NCBI chr 5:121,523,833...121,581,699
Ensembl chr 5:121,527,435...121,581,538
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Acox1
acyl-CoA oxidase 1
decreases expression multiple interactions
ISO
tebuconazole results in decreased expression of ACOX1 mRNA [propiconazole co-treated with tebuconazole] results in decreased expression of ACOX1 mRNA; [tebuconazole co-treated with fludioxonil] results in decreased expression of ACOX1 mRNA
CTD
PMID:30989312 PMID:33575850
NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232
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Acss1
acyl-CoA synthetase short-chain family member 1
decreases expression
ISO
tebuconazole results in decreased expression of ACSS1 mRNA
CTD
PMID:30458266
NCBI chr 3:139,450,383...139,500,325
Ensembl chr 3:139,450,383...139,500,325
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Actl7a
actin-like 7a
decreases expression
ISO
tebuconazole results in decreased expression of ACTL7A mRNA
CTD
PMID:30458266
NCBI chr 5:71,447,447...71,450,440
Ensembl chr 5:71,447,071...71,450,908
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Adamts19
ADAM metallopeptidase with thrombospondin type 1 motif, 19
decreases expression
ISO
tebuconazole results in decreased expression of ADAMTS19 mRNA
CTD
PMID:30458266
NCBI chr18:52,346,448...52,531,245
Ensembl chr18:52,347,428...52,530,509
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Adh4
alcohol dehydrogenase 4 (class II), pi polypeptide
decreases expression
ISO
tebuconazole results in decreased expression of ADH4 mRNA
CTD
PMID:30458266
NCBI chr 2:226,948,717...226,966,747
Ensembl chr 2:226,947,466...226,987,591
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Ahr
aryl hydrocarbon receptor
multiple interactions
ISO
AHR protein affects the reaction [tebuconazole results in increased expression of CYP1A1 mRNA]; AHR protein affects the reaction [tebuconazole results in increased expression of CYP1A2 mRNA]
CTD
PMID:30458266
NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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Akap5
A-kinase anchoring protein 5
decreases expression
ISO
tebuconazole results in decreased expression of AKAP5 mRNA
CTD
PMID:30458266
NCBI chr 6:95,051,527...95,061,075
Ensembl chr 6:95,051,537...95,061,578
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Aknad1
AKNA domain containing 1
decreases expression
ISO
tebuconazole results in decreased expression of AKNAD1 mRNA
CTD
PMID:30458266
NCBI chr 2:196,385,149...196,432,319
Ensembl chr 2:196,393,535...196,432,309
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Akr1b10
aldo-keto reductase family 1 member B10
increases expression multiple interactions
ISO
tebuconazole results in increased expression of AKR1B10 mRNA [propiconazole co-treated with tebuconazole] results in increased expression of AKR1B10 mRNA
CTD
PMID:30989312
NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
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Aldh1a3
aldehyde dehydrogenase 1 family, member A3
decreases expression
ISO
tebuconazole results in decreased expression of ALDH1A3 mRNA
CTD
PMID:30458266
NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436
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Aldob
aldolase, fructose-bisphosphate B
decreases expression
ISO
tebuconazole results in decreased expression of ALDOB mRNA
CTD
PMID:30458266
NCBI chr 5:63,889,045...63,902,086
Ensembl chr 5:63,889,046...63,902,116
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Amotl1
angiomotin-like 1
decreases expression
ISO
tebuconazole results in decreased expression of AMOTL1 mRNA
CTD
PMID:30458266
NCBI chr 8:11,348,651...11,467,564
Ensembl chr 8:11,353,674...11,467,573
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Ankrd61
ankyrin repeat domain 61
decreases expression
ISO
tebuconazole results in decreased expression of ANKRD61 mRNA
CTD
PMID:30458266
NCBI chr12:10,718,908...10,723,267
Ensembl chr12:10,718,908...10,723,265
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Anxa10
annexin A10
increases expression
ISO
tebuconazole results in increased expression of ANXA10 mRNA
CTD
PMID:32194361
NCBI chr16:27,738,712...27,805,648
Ensembl chr16:27,738,712...27,805,648
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Apela
apelin receptor early endogenous ligand
decreases expression
ISO
tebuconazole results in decreased expression of APELA mRNA
CTD
PMID:30458266
NCBI chr16:24,694,356...24,703,466
Ensembl chr16:24,694,324...24,703,465
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Apoa4
apolipoprotein A4
decreases expression
ISO
tebuconazole results in decreased expression of APOA4 mRNA
CTD
PMID:30458266
NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
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Apof
apolipoprotein F
decreases expression
ISO
tebuconazole results in decreased expression of APOF mRNA
CTD
PMID:30458266
NCBI chr 7:700,688...702,130
Ensembl chr 7:700,762...701,946
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Aqp1
aquaporin 1
increases expression
EXP
tebuconazole results in increased expression of AQP1 mRNA
CTD
PMID:33049508
NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690
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Ar
androgen receptor
multiple interactions
ISO
[propiconazole co-treated with prochloraz co-treated with tebuconazole] inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]; [tebuconazole co-treated with prochloraz] inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]; tebuconazole inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; tebuconazole inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]; tebuconazole inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA]; tebuconazole inhibits the reaction [Metribolone results in increased activity of AR protein]
CTD
PMID:18324785 PMID:21310686 PMID:26602169 PMID:33049310
NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
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Arg1
arginase 1
decreases expression
ISO
tebuconazole results in decreased expression of ARG1 mRNA
CTD
PMID:32194361
NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
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Atoh8
atonal bHLH transcription factor 8
decreases expression
ISO
tebuconazole results in decreased expression of ATOH8 mRNA
CTD
PMID:30458266
NCBI chr 4:104,259,992...104,292,168
Ensembl chr 4:104,259,992...104,292,168
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Atp1a2
ATPase Na+/K+ transporting subunit alpha 2
increases expression
EXP
tebuconazole results in increased expression of ATP1A2 mRNA
CTD
PMID:28970091
NCBI chr13:84,729,597...84,754,544
Ensembl chr13:84,729,601...84,754,544
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Atp2b3
ATPase plasma membrane Ca2+ transporting 3
decreases expression
ISO
tebuconazole results in decreased expression of ATP2B3 mRNA
CTD
PMID:30458266
NCBI chr X:151,216,483...151,289,069
Ensembl chr X:151,216,507...151,286,775
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Atxn7l1
ataxin 7-like 1
decreases expression
ISO
tebuconazole results in decreased expression of ATXN7L1 mRNA
CTD
PMID:30458266
NCBI chr 6:49,759,876...49,982,323
Ensembl chr 6:49,759,883...49,982,320
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Basp1
brain abundant, membrane attached signal protein 1
decreases expression
ISO
tebuconazole results in decreased expression of BASP1 mRNA
CTD
PMID:30458266
NCBI chr 2:75,816,130...75,863,801
Ensembl chr 2:75,816,122...75,864,043
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Bax
BCL2 associated X, apoptosis regulator
increases expression
ISO EXP
tebuconazole results in increased expression of BAX protein
CTD
PMID:26852204 PMID:32735800
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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Bcl2
BCL2, apoptosis regulator
decreases expression
ISO EXP
tebuconazole results in decreased expression of BCL2 protein
CTD
PMID:26852204 PMID:32735800
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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Bicra
BRD4 interacting chromatin remodeling complex associated protein
decreases expression
ISO
tebuconazole results in decreased expression of BICRA mRNA
CTD
PMID:30458266
NCBI chr 1:76,661,897...76,736,146
Ensembl chr 1:76,661,897...76,737,157
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Bpi
bactericidal/permeability-increasing protein
decreases expression
ISO
tebuconazole results in decreased expression of BPI mRNA
CTD
PMID:30458266
NCBI chr 3:146,909,626...146,936,487
Ensembl chr 3:146,909,629...146,936,221
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C10h16orf90
similar to human chromosome 16 open reading frame 90
decreases expression
ISO
tebuconazole results in decreased expression of C16ORF90 mRNA
CTD
PMID:30458266
NCBI chr10:11,618,867...11,632,151
Ensembl chr10:11,618,348...11,629,910
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C18h18orf63
similar to human chromosome 18 open reading frame 63
increases expression
ISO
tebuconazole results in increased expression of C18ORF63 mRNA
CTD
PMID:30458266
NCBI chr18:78,159,334...78,202,317
Ensembl chr18:78,164,661...78,202,326
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C3h9orf50
similar to human chromosome 9 open reading frame 50
decreases expression
ISO
tebuconazole results in decreased expression of C9ORF50 mRNA
CTD
PMID:30458266
NCBI chr 3:14,076,679...14,087,036
Ensembl chr 3:14,080,744...14,086,978
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C4h3orf22
similar to human chromosome 3 open reading frame 22
decreases expression
ISO
tebuconazole results in decreased expression of C3ORF22 mRNA
CTD
PMID:30458266
NCBI chr 4:122,817,681...122,822,175
Ensembl chr 4:122,817,681...122,822,175
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C9
complement C9
decreases expression
ISO
tebuconazole results in decreased expression of C9 mRNA
CTD
PMID:30458266
NCBI chr 2:55,573,094...55,621,345
Ensembl chr 2:55,572,992...55,621,338
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Cacna1d
calcium voltage-gated channel subunit alpha1 D
decreases expression
ISO
tebuconazole results in decreased expression of CACNA1D mRNA
CTD
PMID:30458266
NCBI chr16:5,227,157...5,521,163
Ensembl chr16:5,228,306...5,668,215
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Carmn
cardiac mesoderm enhancer-associated non-coding RNA
decreases expression
ISO
tebuconazole results in decreased expression of CARMN mRNA
CTD
PMID:30458266
NCBI chr18:55,097,848...55,118,769
Ensembl chr18:55,095,230...55,118,825
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Casp3
caspase 3
increases cleavage
EXP
tebuconazole results in increased cleavage of CASP3 protein
CTD
PMID:32735800
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Cat
catalase
increases activity
EXP
tebuconazole results in increased activity of CAT protein
CTD
PMID:29923317 PMID:32735800
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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Ccdc168
coiled-coil domain containing 168
decreases expression
ISO
tebuconazole results in decreased expression of CCDC168 mRNA
CTD
PMID:30458266
NCBI chr 9:46,198,234...46,236,325
Ensembl chr 9:46,198,635...46,235,936
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Cd28
Cd28 molecule
decreases expression
ISO
tebuconazole results in decreased expression of CD28 mRNA
CTD
PMID:30458266
NCBI chr 9:62,166,324...62,194,674
Ensembl chr 9:62,166,192...62,194,685
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Cd34
CD34 molecule
increases expression
EXP
tebuconazole results in increased expression of CD34 mRNA; tebuconazole results in increased expression of CD34 protein
CTD
PMID:33049508
NCBI chr13:106,480,313...106,500,844
Ensembl chr13:106,480,043...106,499,832
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Cd36
CD36 molecule
decreases expression multiple interactions increases expression
ISO EXP
tebuconazole results in decreased expression of CD36 mRNA [propiconazole co-treated with tebuconazole] results in decreased expression of CD36 mRNA tebuconazole results in increased expression of CD36 mRNA; tebuconazole results in increased expression of CD36 protein
CTD
PMID:30989312 PMID:33049508
NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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Cdh23
cadherin-related 23
decreases expression
ISO
tebuconazole results in decreased expression of CDH23 mRNA
CTD
PMID:30458266
NCBI chr20:28,240,643...28,622,490
Ensembl chr20:28,240,645...28,622,419
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Cfap276
cilia and flagella associated protein 276
decreases expression
ISO
tebuconazole results in decreased expression of CFAP276 mRNA
CTD
PMID:30458266
NCBI chr 2:196,166,009...196,177,919
Ensembl chr 2:196,166,009...196,177,919
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Cfap58
cilia and flagella associated protein 58
decreases expression
ISO
tebuconazole results in decreased expression of CFAP58 mRNA
CTD
PMID:30458266
NCBI chr 1:246,802,691...246,911,363
Ensembl chr 1:246,802,665...246,911,374
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Cfap61
cilia and flagella associated protein 61
decreases expression
ISO
tebuconazole results in decreased expression of CFAP61 mRNA
CTD
PMID:30458266
NCBI chr 3:133,354,400...133,633,310
Ensembl chr 3:133,354,197...133,633,320
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Cfap97d1
CFAP97 domain containing 1
decreases expression
ISO
tebuconazole results in decreased expression of CFAP97D1 mRNA
CTD
PMID:30458266
NCBI chr10:86,933,585...86,944,566
Ensembl chr10:86,933,808...86,938,244
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Cga
glycoprotein hormones, alpha polypeptide
decreases expression
ISO
tebuconazole results in decreased expression of CGA mRNA
CTD
PMID:26852204
NCBI chr 5:49,486,915...49,499,192
Ensembl chr 5:49,487,068...49,499,191
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Cgref1
cell growth regulator with EF hand domain 1
decreases expression
ISO
tebuconazole results in decreased expression of CGREF1 mRNA
CTD
PMID:30458266
NCBI chr 6:25,431,846...25,443,853
Ensembl chr 6:25,431,799...25,443,852
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Chst13
carbohydrate sulfotransferase 13
decreases expression
ISO
tebuconazole results in decreased expression of CHST13 mRNA
CTD
PMID:30458266
NCBI chr 4:122,824,022...122,837,940
Ensembl chr 4:122,824,022...122,838,019
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Clec2d
C-type lectin domain family 2, member D
decreases expression
ISO
tebuconazole results in decreased expression of CLEC2D mRNA
CTD
PMID:30458266
NCBI chr 4:162,216,052...162,239,530
Ensembl chr 4:162,216,572...162,239,527
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Cox4i2
cytochrome c oxidase subunit 4i2
decreases expression
ISO
tebuconazole results in decreased expression of COX4I2 mRNA
CTD
PMID:30458266
NCBI chr 3:141,228,443...141,239,337
Ensembl chr 3:141,228,443...141,239,331
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Crabp1
cellular retinoic acid binding protein 1
decreases expression
ISO
tebuconazole results in decreased expression of CRABP1 mRNA
CTD
PMID:30458266
NCBI chr 8:55,138,363...55,159,360
Ensembl chr 8:55,151,285...55,159,360
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Crhr1
corticotropin releasing hormone receptor 1
decreases expression
ISO
tebuconazole results in decreased expression of CRHR1 mRNA
CTD
PMID:30458266
NCBI chr10:89,040,186...89,083,481
Ensembl chr10:89,040,203...89,083,481
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Crppa
CDP-L-ribitol pyrophosphorylase A
increases expression
ISO
tebuconazole results in increased expression of CRPPA mRNA
CTD
PMID:30458266
NCBI chr 6:53,120,264...53,397,030
Ensembl chr 6:53,121,438...53,397,028
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Cryba2
crystallin, beta A2
decreases expression
ISO
tebuconazole results in decreased expression of CRYBA2 mRNA
CTD
PMID:30458266
NCBI chr 9:76,447,250...76,457,968
Ensembl chr 9:76,447,251...76,450,460
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Cryga
crystallin, gamma A
decreases expression
ISO
tebuconazole results in decreased expression of CRYGA mRNA
CTD
PMID:30458266
NCBI chr 9:66,482,176...66,484,638
Ensembl chr 9:66,482,176...66,509,896
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Crygd
crystallin, gamma D
decreases expression
ISO
tebuconazole results in decreased expression of CRYGD mRNA
CTD
PMID:30458266
NCBI chr 9:66,442,057...66,443,668
Ensembl chr 9:66,442,054...66,444,067
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Csmd2
CUB and Sushi multiple domains 2
decreases expression
ISO
tebuconazole results in decreased expression of CSMD2 mRNA
CTD
PMID:30458266
NCBI chr 5:140,342,352...140,912,422
Ensembl chr 5:140,342,376...140,912,234
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Cspg4
chondroitin sulfate proteoglycan 4
decreases expression
ISO
tebuconazole results in decreased expression of CSPG4 mRNA
CTD
PMID:30458266
NCBI chr 8:57,264,962...57,300,010
Ensembl chr 8:57,264,962...57,300,010
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Ctnna3
catenin alpha 3
decreases expression
ISO
tebuconazole results in decreased expression of CTNNA3 mRNA
CTD
PMID:30458266
NCBI chr20:23,614,469...25,200,026
Ensembl chr20:23,623,560...25,199,978
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Cyba
cytochrome b-245 alpha chain
increases expression
ISO
tebuconazole results in increased expression of CYBA mRNA
CTD
PMID:30458266
NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
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Cyp19a1
cytochrome P450, family 19, subfamily a, polypeptide 1
decreases activity
ISO
tebuconazole results in decreased activity of CYP19A1 protein
CTD
PMID:12127262
NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758
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Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
increases activity multiple interactions increases expression
ISO EXP
tebuconazole results in increased activity of CYP1A1 protein 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [tebuconazole results in increased expression of CYP1A1 mRNA]; [propiconazole co-treated with tebuconazole] results in increased expression of CYP1A1 mRNA; [tebuconazole co-treated with fludioxonil] results in increased expression of CYP1A1 mRNA; AHR protein affects the reaction [tebuconazole results in increased expression of CYP1A1 mRNA]; tebuconazole inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein] tebuconazole results in increased expression of CYP1A1 mRNA; tebuconazole results in increased expression of CYP1A1 protein
CTD
PMID:19070657 PMID:25233012 PMID:29923317 PMID:30458266 PMID:32194361 PMID:33049508 PMID:33575850 More...
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
multiple interactions increases expression increases activity
ISO EXP
NR1I3 promotes the reaction [tebuconazole results in increased expression of CYP1A2 mRNA] 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [tebuconazole results in increased expression of CYP1A2 mRNA]; [propiconazole co-treated with tebuconazole] results in increased activity of CYP1A2 protein; [propiconazole co-treated with tebuconazole] results in increased expression of CYP1A2 mRNA; [tebuconazole co-treated with fludioxonil] results in increased expression of CYP1A2 mRNA; AHR protein affects the reaction [tebuconazole results in increased expression of CYP1A2 mRNA] tebuconazole results in increased expression of CYP1A2 mRNA; tebuconazole results in increased expression of CYP1A2 protein tebuconazole results in increased activity of CYP1A2 protein
CTD
PMID:25656644 PMID:29923317 PMID:30458266 PMID:33575850
NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
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Cyp26a1
cytochrome P450, family 26, subfamily a, polypeptide 1
increases expression
EXP
tebuconazole results in increased expression of CYP26A1 mRNA
CTD
PMID:28970091
NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204
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Cyp2b1
cytochrome P450, family 2, subfamily b, polypeptide 1
increases expression
EXP
tebuconazole results in increased expression of CYP2B1 protein
CTD
PMID:29923317
NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
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Cyp2b2
cytochrome P450, family 2, subfamily b, polypeptide 2
increases expression
EXP
tebuconazole results in increased expression of CYP2B2 protein
CTD
PMID:29923317
NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566
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Cyp2b3
cytochrome P450, family 2, subfamily b, polypeptide 3
increases expression multiple interactions
ISO
tebuconazole results in increased expression of CYP2B6 mRNA [tebuconazole co-treated with fludioxonil] results in increased expression of CYP2B6 mRNA NR1I3 inhibits the reaction [tebuconazole results in increased expression of CYP2B10 mRNA]
CTD
PMID:25656644 PMID:30458266 PMID:33575850
NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
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Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
decreases expression increases expression
ISO EXP
tebuconazole results in decreased expression of CYP2E1 mRNA tebuconazole results in increased expression of CYP2E1 protein
CTD
PMID:29923317 PMID:30458266
NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
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Cyp2r1
cytochrome P450, family 2, subfamily r, polypeptide 1
decreases expression
ISO
tebuconazole results in decreased expression of CYP2R1 mRNA
CTD
PMID:30458266
NCBI chr 1:168,749,302...168,798,079
Ensembl chr 1:168,751,038...168,797,759
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Cyp3a18
cytochrome P450, family 3, subfamily a, polypeptide 18
increases expression
ISO
tebuconazole results in increased expression of CYP3A43 mRNA
CTD
PMID:30458266
NCBI chr12:8,880,509...8,930,382
Ensembl chr12:8,880,528...8,930,381
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Cyp3a2
cytochrome P450, family 3, subfamily a, polypeptide 2
multiple interactions increases expression decreases activity
ISO
[Amiodarone co-treated with Benzoic Acid co-treated with cyproconazole co-treated with flusilazole co-treated with enilconazole co-treated with prochloraz co-treated with propiconazole co-treated with tebuconazole] results in increased expression of CYP3A4 protein; [tebuconazole results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA tebuconazole results in increased expression of CYP3A4 mRNA tebuconazole results in decreased activity of CYP3A4 protein
CTD
PMID:29420809 PMID:30458266 PMID:33575850 PMID:34273450 PMID:37422065
NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
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Cyp46a1
cytochrome P450, family 46, subfamily a, polypeptide 1
decreases expression
ISO
tebuconazole results in decreased expression of CYP46A1 mRNA
CTD
PMID:30458266
NCBI chr 6:127,247,543...127,274,765
Ensembl chr 6:127,243,315...127,274,760
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Cyp51
cytochrome P450, family 51
decreases activity increases expression
ISO
tebuconazole results in decreased activity of CYP51A1 protein tebuconazole results in increased expression of CYP51 mRNA
CTD
PMID:16989930 PMID:29337257
NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410 Ensembl chr 6:30,036,865...30,055,410
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Cyp7a1
cytochrome P450 family 7 subfamily A member 1
decreases expression
ISO
tebuconazole results in decreased expression of CYP7A1 mRNA
CTD
PMID:30458266 PMID:32194361 PMID:36291160
NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
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Cyp8b1
cytochrome P450 family 8 subfamily B member 1
decreases expression
ISO
tebuconazole results in decreased expression of CYP8B1 mRNA
CTD
PMID:36291160
NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166
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Ddr2
discoidin domain receptor tyrosine kinase 2
decreases expression
ISO
tebuconazole results in decreased expression of DDR2 mRNA
CTD
PMID:30458266
NCBI chr13:82,193,623...82,318,229
Ensembl chr13:82,195,463...82,317,363
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Derl3
derlin 3
decreases expression
ISO
tebuconazole results in decreased expression of DERL3 mRNA
CTD
PMID:30458266
NCBI chr20:12,754,490...12,768,454
Ensembl chr20:12,763,543...12,767,027
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Dnaaf19
dynein axonemal assembly factor 19
decreases expression
ISO
tebuconazole results in decreased expression of DNAAF19 mRNA
CTD
PMID:30458266
NCBI chr10:87,846,327...87,849,959
Ensembl chr10:87,846,357...87,849,757
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Dnah12
dynein, axonemal, heavy chain 12
increases expression
ISO
tebuconazole results in increased expression of DNAH12 mRNA
CTD
PMID:30458266
NCBI chr16:1,936,354...2,092,663
Ensembl chr16:1,937,817...2,092,664
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Dnmt3l
DNA methyltransferase 3 like
decreases expression
ISO
tebuconazole results in decreased expression of DNMT3L mRNA
CTD
PMID:30458266
NCBI chr20:10,614,933...10,629,337
Ensembl chr20:10,614,934...10,629,516
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Drgx
dorsal root ganglia homeobox
decreases expression
ISO
tebuconazole results in decreased expression of DRGX mRNA
CTD
PMID:30458266
NCBI chr16:7,854,849...7,884,404
Ensembl chr16:7,854,849...7,900,600
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Dusp2
dual specificity phosphatase 2
decreases expression
ISO
tebuconazole results in decreased expression of DUSP2 mRNA
CTD
PMID:30458266
NCBI chr 3:114,556,325...114,558,510
Ensembl chr 3:114,556,325...114,558,499
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Dux4
double homeobox 4
decreases expression
ISO
tebuconazole results in decreased expression of DUX4 mRNA
CTD
PMID:30458266
NCBI chr16:1,558,430...1,570,045
Ensembl chr16:1,558,766...1,568,565
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Egflam
EGF-like, fibronectin type III and laminin G domains
decreases expression
ISO
tebuconazole results in decreased expression of EGFLAM mRNA
CTD
PMID:30458266
NCBI chr 2:56,301,945...56,476,665
Ensembl chr 2:56,302,566...56,476,298
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Eif2ak2
eukaryotic translation initiation factor 2-alpha kinase 2
decreases expression
EXP
tebuconazole results in decreased expression of EIF2AK2 mRNA; tebuconazole results in decreased expression of EIF2AK2 protein
CTD
PMID:33049508
NCBI chr 6:16,189,000...16,224,972
Ensembl chr 6:16,188,979...16,224,971
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Esr1
estrogen receptor 1
multiple interactions
ISO
tebuconazole binds to and results in increased activity of ESR1 protein
CTD
PMID:33049310
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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Esrra
estrogen related receptor, alpha
increases expression
EXP
tebuconazole results in increased expression of ESRRA mRNA; tebuconazole results in increased expression of ESRRA protein
CTD
PMID:33049508
NCBI chr 1:204,104,100...204,114,182
Ensembl chr 1:204,104,101...204,114,268
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F13a1
coagulation factor XIII A1 chain
decreases expression
ISO
tebuconazole results in decreased expression of F13A1 mRNA
CTD
PMID:30458266
NCBI chr17:27,815,723...27,992,494
Ensembl chr17:27,815,702...27,992,700
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Fam181a
family with sequence similarity 181, member A
decreases expression
ISO
tebuconazole results in decreased expression of FAM181A mRNA
CTD
PMID:30458266
NCBI chr 6:122,465,373...122,471,397
Ensembl chr 6:122,465,391...122,471,397
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Fam187b
family with sequence similarity 187, member B
decreases expression
ISO
tebuconazole results in decreased expression of FAM187B mRNA
CTD
PMID:30458266
NCBI chr 1:86,205,234...86,219,542
Ensembl chr 1:86,205,218...86,219,917
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Fasn
fatty acid synthase
increases expression multiple interactions
ISO
tebuconazole results in increased expression of FASN mRNA [propiconazole co-treated with tebuconazole] results in increased expression of FASN mRNA
CTD
PMID:30989312
NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
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Fcer1a
Fc epsilon receptor Ia
decreases expression
ISO
tebuconazole results in decreased expression of FCER1A mRNA
CTD
PMID:30458266
NCBI chr13:85,686,099...85,692,394
Ensembl chr13:85,686,092...85,692,351
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Fgf5
fibroblast growth factor 5
decreases expression
ISO
tebuconazole results in decreased expression of FGF5 mRNA
CTD
PMID:30458266
NCBI chr14:11,323,827...11,346,164
Ensembl chr14:11,325,334...11,345,997
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Fgfbp3
fibroblast growth factor binding protein 3
increases expression
EXP
tebuconazole results in increased expression of FGFBP3 mRNA
CTD
PMID:28970091
NCBI chr 1:234,644,023...234,646,028
Ensembl chr 1:234,644,019...234,646,547
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Flna
filamin A
decreases expression
ISO
tebuconazole results in decreased expression of FLNA mRNA
CTD
PMID:30458266
NCBI chr X:152,007,758...152,034,266
Ensembl chr X:152,007,758...152,031,052
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Folr2
folate receptor beta
decreases expression
ISO
tebuconazole results in decreased expression of FOLR2 mRNA
CTD
PMID:30458266
NCBI chr 1:156,200,044...156,218,380
Ensembl chr 1:156,200,060...156,205,724
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Frmpd2
FERM and PDZ domain containing 2
decreases expression
ISO
tebuconazole results in decreased expression of FRMPD2 mRNA
CTD
PMID:30458266
NCBI chr16:8,757,642...8,877,307
Ensembl chr16:8,757,705...8,877,303
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Fscn1
fascin actin-bundling protein 1
decreases expression
ISO
tebuconazole results in decreased expression of FSCN1 mRNA
CTD
PMID:30458266
NCBI chr12:11,597,042...11,610,183
Ensembl chr12:11,597,048...11,610,211
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G6pc1
glucose-6-phosphatase catalytic subunit 1
decreases expression
ISO
tebuconazole results in decreased expression of G6PC1 mRNA
CTD
PMID:30458266 PMID:32194361
NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804
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Gabrp
gamma-aminobutyric acid type A receptor subunit pi
decreases expression
ISO
tebuconazole results in decreased expression of GABRP mRNA
CTD
PMID:30458266
NCBI chr10:18,143,031...18,169,595
Ensembl chr10:18,143,038...18,169,516
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Gadd45b
growth arrest and DNA-damage-inducible, beta
increases expression
ISO
tebuconazole results in increased expression of GADD45B mRNA
CTD
PMID:25656644
NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046
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Gfm1
G elongation factor, mitochondrial 1
increases expression
ISO
tebuconazole results in increased expression of GFM1 mRNA
CTD
PMID:30458266
NCBI chr 2:151,700,573...151,745,477
Ensembl chr 2:151,700,564...151,745,471
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Ghrhr
growth hormone releasing hormone receptor
decreases expression
ISO
tebuconazole results in decreased expression of GHRHR mRNA
CTD
PMID:30458266
NCBI chr 4:84,498,159...84,532,851
Ensembl chr 4:84,500,212...84,532,776
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Gnmt
glycine N-methyltransferase
decreases expression
ISO
tebuconazole results in decreased expression of GNMT mRNA
CTD
PMID:30458266
NCBI chr 9:14,254,675...14,258,028
Ensembl chr 9:14,254,675...14,258,434
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Gp9
glycoprotein IX (platelet)
decreases expression
ISO
tebuconazole results in decreased expression of GP9 mRNA
CTD
PMID:30458266
NCBI chr 4:120,235,500...120,237,110
Ensembl chr 4:120,235,421...120,237,110
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Gpat2
glycerol-3-phosphate acyltransferase 2, mitochondrial
decreases expression
ISO
tebuconazole results in decreased expression of GPAT2 mRNA
CTD
PMID:30458266
NCBI chr 3:114,646,446...114,657,051
Ensembl chr 3:114,648,498...114,657,051
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Gpd1
glycerol-3-phosphate dehydrogenase 1
multiple interactions increases expression
ISO
[propiconazole co-treated with tebuconazole] results in increased expression of GPD1 mRNA tebuconazole results in increased expression of GPD1 mRNA
CTD
PMID:30989312
NCBI chr 7:130,842,526...130,851,530
Ensembl chr 7:130,844,138...130,851,529
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Gsr
glutathione-disulfide reductase
decreases activity
EXP
tebuconazole results in decreased activity of GSR protein
CTD
PMID:32735800
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
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Gstm2
glutathione S-transferase mu 2
increases expression
ISO
tebuconazole results in increased expression of GSTM2 mRNA
CTD
PMID:30458266
NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961
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Guca1b
guanylate cyclase activator 1B
decreases expression
ISO
tebuconazole results in decreased expression of GUCA1B mRNA
CTD
PMID:30458266
NCBI chr 9:13,599,619...13,607,455
Ensembl chr 9:13,599,619...13,607,455
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Hamp
hepcidin antimicrobial peptide
decreases expression
EXP
tebuconazole results in decreased expression of HAMP mRNA
CTD
PMID:33049508
NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
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Hba-a3
hemoglobin alpha, adult chain 3
decreases expression
ISO
tebuconazole results in decreased expression of HBA2 mRNA
CTD
PMID:30458266
NCBI chr10:15,311,637...15,312,481
Ensembl chr10:15,311,634...15,312,481
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Hbb-b1
hemoglobin, beta adult major chain
decreases expression
ISO
tebuconazole results in decreased expression of HBD mRNA
CTD
PMID:30458266
NCBI chr 1:158,224,175...158,231,675
Ensembl chr 1:158,120,200...158,252,012
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Hbegf
heparin-binding EGF-like growth factor
decreases expression
ISO
tebuconazole results in decreased expression of HBEGF mRNA
CTD
PMID:26852204
NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441
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Hbg1
hemoglobin subunit gamma 1
decreases expression
ISO
tebuconazole results in decreased expression of HBG1 mRNA
CTD
PMID:30458266
NCBI chr 1:158,271,871...158,273,426
Ensembl chr 1:158,271,873...158,273,425
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Hbq1b
hemoglobin subunit theta 1B
decreases expression
ISO
tebuconazole results in decreased expression of HBQ1 mRNA
CTD
PMID:30458266
NCBI chr10:15,334,293...15,336,061
Ensembl chr10:15,320,762...15,321,397 Ensembl chr10:15,320,762...15,321,397
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Hdc
histidine decarboxylase
decreases expression
ISO
tebuconazole results in decreased expression of HDC mRNA
CTD
PMID:30458266
NCBI chr 3:113,847,256...113,865,334
Ensembl chr 3:113,847,260...113,865,341
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Heph
hephaestin
decreases expression
ISO
tebuconazole results in decreased expression of HEPH mRNA
CTD
PMID:30458266
NCBI chr X:61,151,131...61,402,980
Ensembl chr X:61,296,345...61,402,980
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Hils1
histone linker H1 domain, spermatid-specific 1
decreases expression
ISO
tebuconazole results in decreased expression of H1-9P mRNA
CTD
PMID:30458266
NCBI chr10:79,913,525...79,914,321
Ensembl chr10:79,913,480...79,914,321
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Hmgcr
3-hydroxy-3-methylglutaryl-CoA reductase
increases expression
ISO
tebuconazole results in increased expression of HMGCR mRNA
CTD
PMID:30458266 PMID:36291160
NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
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Hmgcs1
3-hydroxy-3-methylglutaryl-CoA synthase 1
increases expression
ISO
tebuconazole results in increased expression of HMGCS1 mRNA
CTD
PMID:36291160
NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
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Hmgcs2
3-hydroxy-3-methylglutaryl-CoA synthase 2
decreases expression
ISO
tebuconazole results in decreased expression of HMGCS2 mRNA
CTD
PMID:30458266
NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130
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Hmx1
H6 family homeobox 1
decreases expression
ISO
tebuconazole results in decreased expression of HMX1 mRNA
CTD
PMID:30458266
NCBI chr14:75,361,207...75,364,993
Ensembl chr14:75,361,225...75,364,993
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Homer2
homer scaffold protein 2
decreases expression
ISO
tebuconazole results in decreased expression of HOMER2 mRNA
CTD
PMID:30458266
NCBI chr 1:135,558,977...135,659,780
Ensembl chr 1:135,567,414...135,659,772
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Hsd17b7
hydroxysteroid (17-beta) dehydrogenase 7
increases expression
ISO
tebuconazole results in increased expression of HSD17B7 mRNA
CTD
PMID:30458266
NCBI chr13:82,170,079...82,190,018
Ensembl chr13:82,173,179...82,190,017
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Htr2a
5-hydroxytryptamine receptor 2A
decreases expression
ISO
tebuconazole results in decreased expression of HTR2A mRNA
CTD
PMID:30458266
NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928
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Igsf3
immunoglobulin superfamily, member 3
decreases expression
ISO
tebuconazole results in decreased expression of IGSF3 mRNA
CTD
PMID:30458266
NCBI chr 2:188,811,394...188,899,645
Ensembl chr 2:188,811,380...188,899,645
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Inhbe
inhibin subunit beta E
decreases expression
ISO
tebuconazole results in decreased expression of INHBE mRNA
CTD
PMID:30458266
NCBI chr 7:63,176,221...63,179,209
Ensembl chr 7:63,176,219...63,179,172
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Insig1
insulin induced gene 1
increases expression multiple interactions
ISO
tebuconazole results in increased expression of INSIG1 mRNA [propiconazole co-treated with tebuconazole] results in increased expression of INSIG1 mRNA
CTD
PMID:30458266 PMID:30989312
NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
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Irf6
interferon regulatory factor 6
decreases expression
ISO
tebuconazole results in decreased expression of IRF6 mRNA
CTD
PMID:30458266
NCBI chr13:104,672,179...104,691,386
Ensembl chr13:104,672,179...104,691,386
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Islr2
immunoglobulin superfamily containing leucine-rich repeat 2
decreases expression
ISO
tebuconazole results in decreased expression of ISLR2 mRNA
CTD
PMID:30458266
NCBI chr 8:58,608,165...58,616,246
Ensembl chr 8:58,608,709...58,614,650
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Itgad
integrin subunit alpha D
decreases expression
ISO
tebuconazole results in decreased expression of ITGAD mRNA
CTD
PMID:30458266
NCBI chr 1:182,759,762...182,788,422
Ensembl chr 1:182,759,740...182,788,161
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Jag1
jagged canonical Notch ligand 1
increases expression
EXP
tebuconazole results in increased expression of JAG1 mRNA; tebuconazole results in increased expression of JAG1 protein
CTD
PMID:33049508
NCBI chr 3:124,406,783...124,442,220
Ensembl chr 3:124,406,794...124,442,209
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Jag2
jagged canonical Notch ligand 2
decreases expression
ISO
tebuconazole results in decreased expression of JAG2 mRNA
CTD
PMID:30458266
NCBI chr 6:131,983,059...132,005,665
Ensembl chr 6:131,983,056...132,005,818
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Kcnk7
potassium two pore domain channel subfamily K member 7
decreases expression
ISO
tebuconazole results in decreased expression of KCNK7 mRNA
CTD
PMID:30458266
NCBI chr 1:202,988,801...202,992,842
Ensembl chr 1:202,990,198...202,992,872
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Kdm2b
lysine demethylase 2B
decreases expression
ISO
tebuconazole results in decreased expression of KDM2B mRNA
CTD
PMID:30458266
NCBI chr12:33,566,530...33,701,366
Ensembl chr12:33,574,657...33,701,355
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Kiaa0825
KIAA0825 homolog
decreases expression
ISO
tebuconazole results in decreased expression of KIAA0825 mRNA
CTD
PMID:30458266
NCBI chr 2:6,874,474...7,437,032
Ensembl chr 2:6,874,539...7,434,521
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Kif17
kinesin family member 17
decreases expression
ISO
tebuconazole results in decreased expression of KIF17 mRNA
CTD
PMID:30458266
NCBI chr 5:150,482,288...150,521,471
Ensembl chr 5:150,481,578...150,519,638
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Kif5a
kinesin family member 5A
decreases expression
ISO
tebuconazole results in decreased expression of KIF5A mRNA
CTD
PMID:30458266
NCBI chr 7:63,051,894...63,089,024
Ensembl chr 7:63,049,424...63,092,858
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Kiz
kizuna centrosomal protein
decreases expression
ISO
tebuconazole results in decreased expression of KIZ mRNA
CTD
PMID:30458266
NCBI chr 3:134,277,631...134,385,260
Ensembl chr 3:134,277,687...134,385,190
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Krtap3-1
keratin associated protein 3-1
decreases expression
ISO
tebuconazole results in decreased expression of KRTAP3-1 mRNA
CTD
PMID:30458266
NCBI chr10:84,527,698...84,527,994
Ensembl chr10:84,527,448...84,528,041
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Lbh
LBH regulator of WNT signaling pathway
decreases expression
ISO
tebuconazole results in decreased expression of LBH mRNA
CTD
PMID:30458266
NCBI chr 6:22,569,238...22,593,056
Ensembl chr 6:22,568,834...22,593,079
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Lcn1
lipocalin 1
decreases expression
ISO
tebuconazole results in decreased expression of LCN1 mRNA
CTD
PMID:30458266
NCBI chr 3:9,532,860...9,537,859
Ensembl chr 3:9,532,915...9,536,577
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Lctl
lactase-like
decreases expression
ISO
tebuconazole results in decreased expression of LCTL mRNA
CTD
PMID:30458266
NCBI chr 8:64,618,356...64,654,851
Ensembl chr 8:64,618,350...64,639,357
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Lhx1
LIM homeobox 1
increases expression
EXP
tebuconazole results in increased expression of LHX1 mRNA
CTD
PMID:28970091
NCBI chr10:69,396,829...69,403,617
Ensembl chr10:69,396,829...69,403,617
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Lilrb4
leukocyte immunoglobulin like receptor B4
decreases expression
ISO
tebuconazole results in decreased expression of LILRB4 mRNA
CTD
PMID:30458266
NCBI chr 1:69,805,020...69,810,628
Ensembl chr 1:69,805,250...69,810,660
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Lrrc31
leucine rich repeat containing 31
decreases expression
ISO
tebuconazole results in decreased expression of LRRC31 mRNA
CTD
PMID:30458266
NCBI chr 2:112,702,844...112,725,431
Ensembl chr 2:112,700,136...112,724,322
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Lrrc75a
leucine rich repeat containing 75A
increases expression
EXP
tebuconazole results in increased expression of LRRC75A mRNA
CTD
PMID:28970091
NCBI chr10:47,298,222...47,343,301
Ensembl chr10:47,297,288...47,343,664
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Lrtomt
leucine rich transmembrane and O-methyltransferase domain containing
decreases expression
ISO
tebuconazole results in decreased expression of LRTOMT mRNA
CTD
PMID:30458266
NCBI chr 1:156,266,655...156,268,704
Ensembl chr 1:156,266,655...156,268,704
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Lss
lanosterol synthase
increases expression
ISO
tebuconazole results in increased expression of LSS mRNA
CTD
PMID:30458266 PMID:36291160
NCBI chr20:12,091,138...12,118,858
Ensembl chr20:12,092,774...12,118,762
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Mab21l3
mab-21 like 3
decreases expression
ISO
tebuconazole results in decreased expression of MAB21L3 mRNA
CTD
PMID:30458266
NCBI chr 2:189,248,895...189,271,652
Ensembl chr 2:189,248,895...189,271,652
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Mab21l4
mab-21 like 4
decreases expression
ISO
tebuconazole results in decreased expression of MAB21L4 mRNA
CTD
PMID:30458266
NCBI chr 9:93,690,455...93,701,267
Ensembl chr 9:93,690,999...93,700,506
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Matn1
matrilin 1
decreases expression
ISO
tebuconazole results in decreased expression of MATN1 mRNA
CTD
PMID:30458266
NCBI chr 5:143,117,198...143,127,140
Ensembl chr 5:143,117,504...143,127,059
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Mcf2l
MCF.2 cell line derived transforming sequence-like
decreases expression
ISO
tebuconazole results in decreased expression of MCF2L mRNA
CTD
PMID:30458266
NCBI chr16:76,507,133...76,652,893
Ensembl chr16:76,507,133...76,652,733
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Meg3
maternally expressed 3
decreases expression
ISO
tebuconazole results in decreased expression of MEG3 mRNA
CTD
PMID:30458266
NCBI chr 6:128,491,808...128,524,010
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Mfap5
microfibril associated protein 5
decreases expression
ISO
tebuconazole results in decreased expression of MFAP5 mRNA
CTD
PMID:30458266
NCBI chr 4:155,727,925...155,750,458
Ensembl chr 4:155,727,925...155,750,458
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Miox
myo-inositol oxygenase
decreases expression
ISO
tebuconazole results in decreased expression of MIOX mRNA
CTD
PMID:30458266
NCBI chr 7:120,405,031...120,407,529
Ensembl chr 7:120,405,031...120,407,537
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Mlxipl
MLX interacting protein-like
multiple interactions increases expression
ISO
[propiconazole co-treated with tebuconazole] results in increased expression of MLXIPL mRNA; [tebuconazole co-treated with fludioxonil] results in decreased expression of MLXIPL mRNA tebuconazole results in increased expression of MLXIPL mRNA
CTD
PMID:30989312 PMID:33575850
NCBI chr12:21,541,608...21,577,120
Ensembl chr12:21,543,576...21,577,112
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Mmp2
matrix metallopeptidase 2
decreases expression
ISO
tebuconazole results in decreased expression of MMP2 mRNA
CTD
PMID:26852204
NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
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Mmp21
matrix metallopeptidase 21
decreases expression
ISO
tebuconazole results in decreased expression of MMP21 mRNA
CTD
PMID:30458266
NCBI chr 1:188,480,186...188,485,855
Ensembl chr 1:188,480,186...188,485,855
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Mmp9
matrix metallopeptidase 9
decreases expression
ISO
tebuconazole results in decreased expression of MMP9 mRNA
CTD
PMID:26852204
NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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Mrgpre
MAS related GPR family member E
decreases expression
ISO
tebuconazole results in decreased expression of MRGPRE mRNA
CTD
PMID:30458266
NCBI chr 1:198,963,786...198,969,862
Ensembl chr 1:198,963,787...198,969,521
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Mro
maestro
decreases expression
ISO
tebuconazole results in decreased expression of MRO mRNA
CTD
PMID:30458266
NCBI chr18:67,450,186...67,467,593
Ensembl chr18:67,450,595...67,467,044
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Msmo1
methylsterol monooxygenase 1
increases expression
EXP ISO
tebuconazole results in increased expression of MSMO1 mRNA
CTD
PMID:28970091 PMID:29337257 PMID:36291160
NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016
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Msx2
msh homeobox 2
decreases expression
ISO
tebuconazole results in decreased expression of MSX2 mRNA
CTD
PMID:30458266
NCBI chr17:11,097,214...11,102,879
Ensembl chr17:11,097,103...11,102,879
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Muc3a
mucin 3A, cell surface associated
decreases expression
ISO
tebuconazole results in decreased expression of MUC3A mRNA
CTD
PMID:30458266
NCBI chr12:19,450,679...19,454,753
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Muc5ac
mucin 5AC, oligomeric mucus/gel-forming
decreases expression
ISO
tebuconazole results in decreased expression of MUC5AC mRNA
CTD
PMID:30458266
NCBI chr 1:196,864,336...196,896,475
Ensembl chr 1:196,864,336...196,896,475
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Mvd
mevalonate diphosphate decarboxylase
increases expression
ISO
tebuconazole results in increased expression of MVD mRNA
CTD
PMID:30458266
NCBI chr19:50,496,366...50,506,429
Ensembl chr19:50,496,367...50,507,971
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Myog
myogenin
decreases expression
ISO
tebuconazole results in decreased expression of MYOG mRNA
CTD
PMID:30458266
NCBI chr13:45,745,455...45,748,044
Ensembl chr13:45,745,436...45,748,039
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Myrfl
myelin regulatory factor-like
decreases expression
ISO
tebuconazole results in decreased expression of MYRFL mRNA
CTD
PMID:30458266
NCBI chr 7:52,403,324...52,519,907
Ensembl chr 7:52,403,650...52,519,907
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Ndnf
neuron-derived neurotrophic factor
increases expression
EXP
tebuconazole results in increased expression of NDNF mRNA
CTD
PMID:28970091
NCBI chr 4:94,944,392...94,981,871
Ensembl chr 4:94,944,360...94,981,873
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Ngfr
nerve growth factor receptor
increases expression
EXP
tebuconazole results in increased expression of NGFR mRNA
CTD
PMID:28970091
NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518
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Niban1
niban apoptosis regulator 1
decreases expression
ISO
tebuconazole results in decreased expression of NIBAN1 mRNA
CTD
PMID:30458266
NCBI chr13:63,674,240...63,827,748
Ensembl chr13:63,674,171...63,827,729
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Nid2
nidogen 2
decreases expression
ISO
tebuconazole results in decreased expression of NID2 mRNA
CTD
PMID:30458266
NCBI chr15:4,458,082...4,513,808
Ensembl chr15:4,458,084...4,513,843
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Nphs2
NPHS2 stomatin family member, podocin
decreases expression
ISO
tebuconazole results in decreased expression of NPHS2 mRNA
CTD
PMID:30458266
NCBI chr13:68,448,720...68,461,312
Ensembl chr13:68,448,926...68,461,313
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Nr1i2
nuclear receptor subfamily 1, group I, member 2
increases activity multiple interactions
ISO
tebuconazole results in increased activity of NR1I2 protein [tebuconazole results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; tebuconazole binds to and results in increased activity of NR1I2 protein
CTD
PMID:28728110 PMID:29420809 PMID:33049310 PMID:36291160
NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
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Nr1i3
nuclear receptor subfamily 1, group I, member 3
affects response to substance multiple interactions increases response to substance decreases expression decreases activity
ISO EXP
NR1I3 protein affects the susceptibility to tebuconazole NR1I3 inhibits the reaction [tebuconazole results in increased expression of CYP2B10 mRNA]; NR1I3 promotes the reaction [tebuconazole results in increased expression of CYP1A2 mRNA]; NR1I3 promotes the reaction [tebuconazole results in increased expression of CYP4A10 mRNA]; NR1I3 promotes the reaction [tebuconazole results in increased expression of POR mRNA] NR1I3 results in increased susceptibility to tebuconazole tebuconazole binds to and results in decreased activity of NR1I3 protein [tebuconazole co-treated with fludioxonil] results in decreased expression of NR1I3 mRNA; tebuconazole binds to and results in decreased activity of NR1I3 protein tebuconazole results in decreased expression of NR1I3 mRNA tebuconazole results in decreased activity of NR1I3 protein
CTD
PMID:23721867 PMID:25656644 PMID:29420809 PMID:33575850 PMID:36291160
NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
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Nutm1
NUT midline carcinoma, family member 1
increases expression
ISO
tebuconazole results in increased expression of NUTM1 mRNA
CTD
PMID:30458266
NCBI chr 3:99,053,510...99,064,311
Ensembl chr 3:99,053,510...99,064,311
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Obscn
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
decreases expression
ISO
tebuconazole results in decreased expression of OBSCN mRNA
CTD
PMID:30458266
NCBI chr10:43,774,113...43,919,718
Ensembl chr10:43,789,293...43,919,723
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Odf4
outer dense fiber of sperm tails 4
decreases expression
ISO
tebuconazole results in decreased expression of ODF4 mRNA
CTD
PMID:30458266
NCBI chr10:53,628,592...53,634,525
Ensembl chr10:53,628,759...53,634,359
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Oprl1
opioid related nociceptin receptor 1
decreases expression
ISO
tebuconazole results in decreased expression of OPRL1 mRNA
CTD
PMID:30458266
NCBI chr 3:168,831,934...168,839,920
Ensembl chr 3:168,834,003...168,839,920
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Or10c1
olfactory receptor family 10 subfamily C member 1
decreases expression
ISO
tebuconazole results in decreased expression of OR10C1 mRNA
CTD
PMID:30458266
NCBI chr20:1,370,602...1,371,540
Ensembl chr20:1,370,586...1,371,563
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Or2t1
olfactory receptor family 2 subfamily T member 1
decreases expression
ISO
tebuconazole results in decreased expression of OR2T1 mRNA
CTD
PMID:30458266
NCBI chr15:10,960,562...10,961,515
Ensembl chr15:10,954,685...10,966,743
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Or4d10c
olfactory receptor family 4 subfamily D member 10C
decreases expression
ISO
tebuconazole results in decreased expression of OR4D10 mRNA
CTD
PMID:30458266
NCBI chr 1:209,016,663...209,017,598
Ensembl chr 1:209,015,124...209,020,125
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Pabpn1l
PABPN1 like
decreases expression
ISO
tebuconazole results in decreased expression of PABPN1L mRNA
CTD
PMID:30458266
NCBI chr19:50,669,965...50,673,409
Ensembl chr19:50,669,967...50,673,366
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Pak1
p21 (RAC1) activated kinase 1
decreases expression
ISO
tebuconazole results in decreased expression of PAK1 mRNA
CTD
PMID:30458266
NCBI chr 1:152,111,172...152,226,390
Ensembl chr 1:152,111,188...152,226,383
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Palld
palladin, cytoskeletal associated protein
decreases expression
ISO
tebuconazole results in decreased expression of PALLD mRNA
CTD
PMID:30458266
NCBI chr16:28,228,006...28,621,349
Ensembl chr16:27,981,354...28,621,337
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Panx3
pannexin 3
decreases expression
ISO
tebuconazole results in decreased expression of PANX3 mRNA
CTD
PMID:30458266
NCBI chr 8:37,366,758...37,377,640
Ensembl chr 8:37,366,862...37,377,640
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Pgf
placental growth factor
decreases expression
ISO
tebuconazole results in decreased expression of PGF mRNA
CTD
PMID:26852204
NCBI chr 6:104,816,102...104,826,685
Ensembl chr 6:104,816,104...104,826,685
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Plau
plasminogen activator, urokinase
decreases expression
ISO
tebuconazole results in decreased expression of PLAU mRNA
CTD
PMID:26852204
NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
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Plekhg7
pleckstrin homology and RhoGEF domain containing G7
decreases expression
ISO
tebuconazole results in decreased expression of PLEKHG7 mRNA
CTD
PMID:30458266
NCBI chr 7:30,727,952...30,805,866
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Pln
phospholamban
increases expression
EXP
tebuconazole results in increased expression of PLN mRNA
CTD
PMID:33049508
NCBI chr20:32,629,537...32,639,559
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Pnliprp1
pancreatic lipase-related protein 1
decreases expression
ISO
tebuconazole results in decreased expression of PNLIPRP1 mRNA
CTD
PMID:30458266
NCBI chr 1:257,867,885...257,883,514
Ensembl chr 1:257,867,885...257,883,514
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Por
cytochrome p450 oxidoreductase
increases expression multiple interactions
ISO
tebuconazole results in increased expression of POR mRNA NR1I3 promotes the reaction [tebuconazole results in increased expression of POR mRNA]
CTD
PMID:25656644
NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
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Pparg
peroxisome proliferator-activated receptor gamma
multiple interactions
ISO
tebuconazole binds to and results in increased activity of PPARG protein
CTD
PMID:33049310
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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Pramef8
PRAME family member 8
decreases expression
ISO
tebuconazole results in decreased expression of PRAMEF8 mRNA
CTD
PMID:30458266
NCBI chr 5:155,778,156...155,793,935
Ensembl chr 5:155,778,201...155,793,932
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Prg2
proteoglycan 2, pro eosinophil major basic protein
decreases expression
ISO
tebuconazole results in decreased expression of PRG2 mRNA
CTD
PMID:30458266
NCBI chr 3:70,062,535...70,066,102
Ensembl chr 3:70,062,535...70,066,101
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Prkaa1
protein kinase AMP-activated catalytic subunit alpha 1
multiple interactions
ISO
[tebuconazole co-treated with Econazole] results in increased phosphorylation of PRKAA1 protein
CTD
PMID:30698772
NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
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Prkaa2
protein kinase AMP-activated catalytic subunit alpha 2
multiple interactions
ISO
[tebuconazole co-treated with Econazole] results in increased phosphorylation of PRKAA2 protein
CTD
PMID:30698772
NCBI chr 5:119,807,992...119,879,987
Ensembl chr 5:119,813,226...119,879,543
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Prss3
serine protease 3
decreases expression
ISO
tebuconazole results in decreased expression of PRSS3 mRNA
CTD
PMID:30458266
NCBI chr 4:70,203,088...70,206,562
Ensembl chr 4:70,203,088...70,206,562
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Ptgs2
prostaglandin-endoperoxide synthase 2
multiple interactions
ISO
[tebuconazole binds to and results in decreased activity of PTGS2 protein] which results in decreased chemical synthesis of and results in decreased secretion of Prostaglandin D2
CTD
PMID:26359731
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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Ptprc
protein tyrosine phosphatase, receptor type, C
increases expression
ISO
tebuconazole results in increased expression of PTPRC mRNA
CTD
PMID:30458266
NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692
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Purg
purine-rich element binding protein G
decreases expression
ISO
tebuconazole results in decreased expression of PURG mRNA
CTD
PMID:30458266
NCBI chr16:58,732,327...58,763,356
Ensembl chr16:58,720,335...58,763,359
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Rai1
retinoic acid induced 1
decreases expression
ISO
tebuconazole results in decreased expression of RAI1 mRNA
CTD
PMID:30458266
NCBI chr10:44,913,231...45,008,232
Ensembl chr10:44,947,909...45,008,232
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Rasal2
RAS protein activator like 2
decreases expression
ISO
tebuconazole results in decreased expression of RASAL2 mRNA
CTD
PMID:30458266
NCBI chr13:69,279,882...69,569,161
Ensembl chr13:69,258,622...69,569,940
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Rasd1
ras related dexamethasone induced 1
increases expression
EXP
tebuconazole results in increased expression of RASD1 mRNA
CTD
PMID:28970091
NCBI chr10:44,766,451...44,775,773
Ensembl chr10:44,766,455...44,768,186
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Ret
ret proto-oncogene
decreases expression
ISO
tebuconazole results in decreased expression of RET mRNA
CTD
PMID:30458266
NCBI chr 4:151,325,969...151,368,176
Ensembl chr 4:151,326,431...151,368,176
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Rnd1
Rho family GTPase 1
decreases expression
ISO
tebuconazole results in decreased expression of RND1 mRNA
CTD
PMID:30458266
NCBI chr 7:129,821,311...129,828,385
Ensembl chr 7:129,821,311...129,828,399
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Rnf112
ring finger protein 112
increases expression
ISO
tebuconazole results in increased expression of RNF112 mRNA
CTD
PMID:30458266
NCBI chr10:46,121,146...46,126,691
Ensembl chr10:46,121,148...46,126,699
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Rpp25
ribonuclease P and MRP subunit p25
decreases expression
ISO
tebuconazole results in decreased expression of RPP25 mRNA
CTD
PMID:30458266
NCBI chr 8:57,907,352...57,908,732
Ensembl chr 8:57,907,352...57,908,732
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Rps6kl1
ribosomal protein S6 kinase-like 1
decreases expression
ISO
tebuconazole results in decreased expression of RPS6KL1 mRNA
CTD
PMID:30458266
NCBI chr 6:104,783,227...104,799,895
Ensembl chr 6:104,783,258...104,799,869
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Rtp3
receptor (chemosensory) transporter protein 3
decreases expression
ISO
tebuconazole results in decreased expression of RTP3 mRNA
CTD
PMID:30458266
NCBI chr 8:110,970,154...110,975,000
Ensembl chr 8:110,970,160...110,974,699
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Runx2
RUNX family transcription factor 2
decreases expression
ISO
tebuconazole results in decreased expression of RUNX2 mRNA
CTD
PMID:30458266
NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
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Sc5d
sterol-C5-desaturase
increases expression
EXP
tebuconazole results in increased expression of SC5D mRNA
CTD
PMID:28970091
NCBI chr 8:42,629,649...42,641,257
Ensembl chr 8:42,632,672...42,641,273
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Scn4b
sodium voltage-gated channel beta subunit 4
decreases expression
ISO
tebuconazole results in decreased expression of SCN4B mRNA
CTD
PMID:30458266
NCBI chr 8:45,446,580...45,462,294
Ensembl chr 8:45,446,215...45,462,292
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Scube1
signal peptide, CUB domain and EGF like domain containing 1
increases expression
EXP
tebuconazole results in increased expression of SCUBE1 mRNA
CTD
PMID:28970091
NCBI chr 7:114,759,016...114,880,995
Ensembl chr 7:114,759,010...114,880,940
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Sec14l3
SEC14-like lipid binding 3
decreases expression
ISO
tebuconazole results in decreased expression of SEC14L3 mRNA
CTD
PMID:30458266
NCBI chr14:78,944,568...78,955,608
Ensembl chr14:78,912,750...78,956,099
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Sele
selectin E
decreases expression
ISO
tebuconazole results in decreased expression of SELE mRNA
CTD
PMID:30458266
NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
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Serpine2
serpin family E member 2
increases expression
ISO
tebuconazole results in increased expression of SERPINE2 mRNA
CTD
PMID:26852204
NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826
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Sh2d2a
SH2 domain containing 2A
decreases expression
ISO
tebuconazole results in decreased expression of SH2D2A mRNA
CTD
PMID:30458266
NCBI chr 2:173,312,253...173,318,810
Ensembl chr 2:173,312,253...173,318,810
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Siglec10
sialic acid binding Ig-like lectin 10
decreases expression
ISO
tebuconazole results in decreased expression of SIGLEC10 mRNA
CTD
PMID:30458266
NCBI chr 1:93,817,301...93,826,376
Ensembl chr 1:93,817,335...93,825,931
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Sla
src-like adaptor
increases expression
ISO
tebuconazole results in increased expression of SLA mRNA
CTD
PMID:30458266
NCBI chr 7:98,534,431...98,584,810
Ensembl chr 7:98,535,368...98,584,648
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Slc10a1
solute carrier family 10 member 1
decreases expression
ISO
tebuconazole results in decreased expression of SLC10A1 mRNA
CTD
PMID:36291160
NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670
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Slc16a11
solute carrier family 16, member 11
decreases expression
ISO
tebuconazole results in decreased expression of SLC16A11 mRNA
CTD
PMID:30458266
NCBI chr10:54,929,129...54,933,021
Ensembl chr10:54,927,725...54,942,915
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Slc22a15
solute carrier family 22, member 15
increases expression
ISO
tebuconazole results in increased expression of SLC22A15 mRNA
CTD
PMID:30458266
NCBI chr 2:189,298,836...189,359,902
Ensembl chr 2:189,298,832...189,358,792
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Slc22a7
solute carrier family 22 member 7
decreases expression
ISO
tebuconazole results in decreased expression of SLC22A7 mRNA
CTD
PMID:30458266
NCBI chr 9:14,547,073...14,554,354
Ensembl chr 9:14,547,849...14,553,921
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Slc22a8
solute carrier family 22 member 8
decreases activity
ISO
tebuconazole results in decreased activity of SLC22A8 protein
CTD
PMID:36669674
NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450
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Slc4a1
solute carrier family 4 member 1 (Diego blood group)
decreases expression
ISO
tebuconazole results in decreased expression of SLC4A1 mRNA
CTD
PMID:30458266
NCBI chr10:87,306,865...87,323,132
Ensembl chr10:87,306,872...87,323,117
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Slc51a
solute carrier family 51 member A
decreases expression
ISO
tebuconazole results in decreased expression of SLC51A mRNA
CTD
PMID:36291160
NCBI chr11:68,299,086...68,313,485
Ensembl chr11:68,299,086...68,313,485
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Slc5a5
solute carrier family 5 member 5
decreases expression
ISO
tebuconazole results in decreased expression of SLC5A5 mRNA
CTD
PMID:30458266
NCBI chr16:18,546,709...18,556,698
Ensembl chr16:18,546,709...18,556,697
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Slc6a5
solute carrier family 6 member 5
decreases expression
ISO
tebuconazole results in decreased expression of SLC6A5 mRNA
CTD
PMID:30458266
NCBI chr 1:99,645,389...99,697,016
Ensembl chr 1:99,645,389...99,697,010
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Slc9a1
solute carrier family 9 member A1
decreases expression
ISO
tebuconazole results in decreased expression of SLC9A1 mRNA
CTD
PMID:30458266
NCBI chr 5:145,576,341...145,629,630
Ensembl chr 5:145,576,334...145,629,624
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Slit1
slit guidance ligand 1
decreases expression
ISO
tebuconazole results in decreased expression of SLIT1 mRNA
CTD
PMID:30458266
NCBI chr 1:240,409,559...240,558,127
Ensembl chr 1:240,409,561...240,558,127
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Smco1
single-pass membrane protein with coiled-coil domains 1
decreases expression
ISO
tebuconazole results in decreased expression of SMCO1 mRNA
CTD
PMID:30458266
NCBI chr11:68,512,113...68,514,999
Ensembl chr11:68,509,150...68,515,003
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Snai1
snail family transcriptional repressor 1
increases expression
ISO
tebuconazole results in increased expression of SNAI1 mRNA
CTD
PMID:30458266
NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
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Spdef
SAM pointed domain containing ets transcription factor
decreases expression
ISO
tebuconazole results in decreased expression of SPDEF mRNA
CTD
PMID:30458266
NCBI chr20:5,771,440...5,785,893
Ensembl chr20:5,771,441...5,785,893
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Spi1
Spi-1 proto-oncogene
decreases expression
ISO
tebuconazole results in decreased expression of SPI1 mRNA
CTD
PMID:30458266
NCBI chr 3:77,059,744...77,093,730
Ensembl chr 3:77,073,012...77,092,393
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Sqle
squalene epoxidase
increases expression
ISO
tebuconazole results in increased expression of SQLE mRNA
CTD
PMID:30458266
NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618
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Srebf1
sterol regulatory element binding transcription factor 1
multiple interactions increases expression
ISO
[propiconazole co-treated with tebuconazole] results in increased expression of SREBF1 mRNA tebuconazole results in increased expression of SREBF1 mRNA
CTD
PMID:30989312
NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
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Srms
src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites
decreases expression
ISO
tebuconazole results in decreased expression of SRMS mRNA
CTD
PMID:30458266
NCBI chr 3:168,318,511...168,324,915
Ensembl chr 3:168,318,512...168,324,915
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Stum
stum, mechanosensory transduction mediator homolog
decreases expression
ISO
tebuconazole results in decreased expression of STUM mRNA
CTD
PMID:30458266
NCBI chr13:92,172,175...92,227,205
Ensembl chr13:92,173,544...92,227,213
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Sult1e1
sulfotransferase family 1E member 1
decreases expression
ISO
tebuconazole results in decreased expression of SULT1E1 mRNA
CTD
PMID:30458266
NCBI chr14:20,422,324...20,439,562
Ensembl chr14:20,422,324...20,439,275
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Syngap1
synaptic Ras GTPase activating protein 1
decreases expression
ISO
tebuconazole results in decreased expression of SYNGAP1 mRNA
CTD
PMID:30458266
NCBI chr20:5,026,366...5,056,659
Ensembl chr20:5,026,364...5,056,672
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Tbx2
T-box transcription factor 2
decreases expression
ISO
tebuconazole results in decreased expression of TBX2 mRNA
CTD
PMID:30458266
NCBI chr10:70,679,670...70,688,868
Ensembl chr10:70,679,518...70,688,529
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Tbx21
T-box transcription factor 21
increases expression
ISO
tebuconazole results in increased expression of TBX21 mRNA
CTD
PMID:30458266
NCBI chr10:82,082,322...82,098,831
Ensembl chr10:82,082,322...82,098,831
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Terf1
telomeric repeat binding factor 1
decreases expression
ISO
tebuconazole results in decreased expression of TERF1 mRNA
CTD
PMID:30458266
NCBI chr 5:3,443,103...3,472,377
Ensembl chr 5:3,443,106...3,472,340
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Tex38
testis expressed 38
increases expression
ISO
tebuconazole results in increased expression of TEX38 mRNA
CTD
PMID:30458266
NCBI chr 5:129,260,652...129,265,086
Ensembl chr 5:129,261,552...129,264,673
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Tfrc
transferrin receptor
decreases expression
EXP
tebuconazole results in decreased expression of TFRC mRNA; tebuconazole results in decreased expression of TFRC protein
CTD
PMID:33049508
NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
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Ticrr
TOPBP1-interacting checkpoint and replication regulator
increases expression
ISO
tebuconazole results in increased expression of TICRR mRNA
CTD
PMID:30458266
NCBI chr 1:133,597,618...133,639,513
Ensembl chr 1:133,597,716...133,639,523
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Timp1
TIMP metallopeptidase inhibitor 1
increases expression
ISO
tebuconazole results in increased expression of TIMP1 mRNA
CTD
PMID:26852204
NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
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Timp2
TIMP metallopeptidase inhibitor 2
increases expression
ISO
tebuconazole results in increased expression of TIMP2 mRNA
CTD
PMID:26852204
NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611
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Tm6sf2
transmembrane 6 superfamily member 2
decreases expression
ISO
tebuconazole results in decreased expression of TM6SF2 mRNA
CTD
PMID:30458266
NCBI chr16:19,344,218...19,351,431
Ensembl chr16:19,344,222...19,351,431
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Tmed3
transmembrane p24 trafficking protein 3
decreases expression
ISO
tebuconazole results in decreased expression of TMED3 mRNA
CTD
PMID:30458266
NCBI chr 8:90,241,516...90,249,429
Ensembl chr 8:90,241,516...90,249,346
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Tmem106b
transmembrane protein 106B
increases expression
ISO
tebuconazole results in increased expression of TMEM106B mRNA
CTD
PMID:30458266
NCBI chr 4:41,328,125...41,347,315
Ensembl chr 4:41,327,994...41,345,619
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Tmem125
transmembrane protein 125
decreases expression
ISO
tebuconazole results in decreased expression of TMEM125 mRNA
CTD
PMID:30458266
NCBI chr 5:132,063,162...132,064,566
Ensembl chr 5:132,059,554...132,079,297 Ensembl chr 5:132,059,554...132,079,297
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Tmem179
transmembrane protein 179
decreases expression
ISO
tebuconazole results in decreased expression of TMEM179 mRNA
CTD
PMID:30458266
NCBI chr 6:131,569,289...131,580,413
Ensembl chr 6:131,569,290...131,580,305
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Tmem97
transmembrane protein 97
increases expression
ISO
tebuconazole results in increased expression of TMEM97 mRNA
CTD
PMID:30458266
NCBI chr10:63,438,228...63,447,311
Ensembl chr10:63,438,222...63,589,730
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Tnf
tumor necrosis factor
decreases expression
ISO
tebuconazole results in decreased expression of TNF mRNA
CTD
PMID:26852204
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Tnni1
troponin I1, slow skeletal type
decreases expression
ISO
tebuconazole results in decreased expression of TNNI1 mRNA
CTD
PMID:30458266
NCBI chr13:47,229,217...47,241,640
Ensembl chr13:47,229,216...47,241,644
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Tnnt3
troponin T3, fast skeletal type
decreases expression
ISO
tebuconazole results in decreased expression of TNNT3 mRNA
CTD
PMID:30458266
NCBI chr 1:197,652,535...197,669,736
Ensembl chr 1:197,652,431...197,669,535
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Tnrc18
trinucleotide repeat containing 18
decreases expression
ISO
tebuconazole results in decreased expression of TNRC18 mRNA
CTD
PMID:30458266
NCBI chr12:11,755,394...11,851,717
Ensembl chr12:11,755,392...11,851,384
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Tpbgl
trophoblast glycoprotein-like
decreases expression
ISO
tebuconazole results in decreased expression of TPBGL mRNA
CTD
PMID:30458266
NCBI chr 1:153,923,722...153,926,548
Ensembl chr 1:153,925,098...153,926,252
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Trpv6
transient receptor potential cation channel, subfamily V, member 6
decreases expression
ISO
tebuconazole results in decreased expression of TRPV6 mRNA
CTD
PMID:30458266
NCBI chr 4:70,507,347...70,523,013
Ensembl chr 4:70,507,348...70,523,017
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Tstd2
thiosulfate sulfurtransferase like domain containing 2
decreases expression
ISO
tebuconazole results in decreased expression of TSTD2 mRNA
CTD
PMID:30458266
NCBI chr 5:60,371,751...60,415,916
Ensembl chr 5:60,393,454...60,415,916
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Txnl1
thioredoxin-like 1
decreases expression
ISO
tebuconazole results in decreased expression of TXNL1 mRNA
CTD
PMID:30458266
NCBI chr18:57,125,362...57,155,167
Ensembl chr18:57,125,369...57,165,266
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Ubl4b
ubiquitin-like 4B
decreases expression
ISO
tebuconazole results in decreased expression of UBL4B mRNA
CTD
PMID:30458266
NCBI chr 2:195,192,490...195,193,820
Ensembl chr 2:195,191,720...195,193,875
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Ubr4
ubiquitin protein ligase E3 component n-recognin 4
decreases expression
ISO
tebuconazole results in decreased expression of UBR4 mRNA
CTD
PMID:30458266
NCBI chr 5:151,635,825...151,743,931
Ensembl chr 5:151,635,868...151,743,784
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Ugt1a1
UDP glucuronosyltransferase family 1 member A1
increases expression
ISO
tebuconazole results in increased expression of UGT1A1 mRNA
CTD
PMID:30458266
NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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Ulk1
unc-51 like autophagy activating kinase 1
multiple interactions
ISO
[tebuconazole co-treated with Econazole] results in increased phosphorylation of ULK1 protein; dorsomorphin inhibits the reaction [[tebuconazole co-treated with Econazole] results in increased phosphorylation of ULK1 protein]
CTD
PMID:30698772
NCBI chr12:45,851,710...45,877,966
Ensembl chr12:45,851,710...45,877,966
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Vegfc
vascular endothelial growth factor C
decreases expression
ISO
tebuconazole results in decreased expression of VEGFC mRNA
CTD
PMID:26852204
NCBI chr16:37,712,251...37,827,845
Ensembl chr16:37,712,262...37,827,848
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Wdr37
WD repeat domain 37
decreases expression
ISO
tebuconazole results in decreased expression of WDR37 mRNA
CTD
PMID:30458266
NCBI chr17:61,637,258...61,703,677
Ensembl chr17:61,637,258...61,703,677
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Wdr38
WD repeat domain 38
decreases expression
ISO
tebuconazole results in decreased expression of WDR38 mRNA
CTD
PMID:30458266
NCBI chr 3:22,750,150...22,753,260
Ensembl chr 3:22,749,396...22,753,259
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Wdr5b
WD repeat domain 5B
decreases expression
ISO
tebuconazole results in decreased expression of WDR5B mRNA
CTD
PMID:30458266
NCBI chr11:64,710,945...64,712,804
Ensembl chr11:64,710,355...64,712,807
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Wfdc2
WAP four-disulfide core domain 2
decreases expression
ISO
tebuconazole results in decreased expression of WFDC2 mRNA
CTD
PMID:30458266
NCBI chr 3:153,286,946...153,314,832
Ensembl chr 3:153,286,131...153,292,807
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Wnt1
Wnt family member 1
decreases expression
ISO
tebuconazole results in decreased expression of WNT1 mRNA
CTD
PMID:30458266
NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651
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Wnt10a
Wnt family member 10A
decreases expression
ISO
tebuconazole results in decreased expression of WNT10A mRNA
CTD
PMID:30458266
NCBI chr 9:76,349,931...76,362,400
Ensembl chr 9:76,349,931...76,362,400
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Zfp7
zinc finger protein 7
decreases expression
ISO
tebuconazole results in decreased expression of ZNF7 mRNA
CTD
PMID:30458266
NCBI chr 7:108,598,666...108,615,740
Ensembl chr 7:108,607,689...108,618,185
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Zg16
zymogen granule protein 16
decreases expression
ISO
tebuconazole results in decreased expression of ZG16 mRNA
CTD
PMID:30458266
NCBI chr 1:181,657,722...181,660,079
Ensembl chr 1:181,657,722...181,660,079
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Znf568l-ps1
zinc finger protein 568 like, pseudogene 1
decreases expression
ISO
tebuconazole results in decreased expression of ZNF568 mRNA
CTD
PMID:30458266
NCBI chr 1:85,229,794...85,231,191
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Zscan12
zinc finger and SCAN domain containing 12
decreases expression
ISO
tebuconazole results in decreased expression of ZSCAN12 mRNA
CTD
PMID:30458266
NCBI chr17:43,247,250...43,253,206
Ensembl chr17:43,247,095...43,253,264
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