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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:pralidoxime
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Accession:CHEBI:8354 term browser browse the term
Definition:A pyridinium ion that is 1-methylpyridinium substituted by a (hydroxyimino)methyl group at position 2.
Synonyms:exact_synonym: 2-[(E)-(hydroxyimino)methyl]-1-methylpyridinium
 related_synonym: 2-PAM;   Formula=C7H9N2O;   InChI=1S/C7H8N2O/c1-9-5-3-2-4-7(9)6-8-10/h2-6H,1H3/p+1;   InChIKey=JBKPUQTUERUYQE-UHFFFAOYSA-O;   Pralidoximum;   SMILES=C[n+]1ccccc1\\C=N\\O
 xref: CAS:6735-59-7;   DrugBank:DB00733;   Drug_Central:2231;   HMDB:HMDB0014871;   KEGG:C07400;   LINCS:LSM-5708
 xref_mesh: MESH:C028797
 xref: PMID:24625936;   Reaxys:1526531;   Wikipedia:Pralidoxime


show annotations for term's descendants           Sort by:
pralidoxime term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACHE acetylcholinesterase multiple interactions EXP pralidoxime inhibits the reaction [Paraoxon results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [tabun results in decreased activity of ACHE protein] CTD PMID:20370537 PMID:20971170 NCBI chr 3:8,732,451...8,738,274
Ensembl chr 3:8,732,441...8,738,605 		JBrowse link
G MAOA monoamine oxidase A decreases activity EXP pralidoxime results in decreased activity of MAOA protein CTD PMID:21195145 NCBI chr  X:38,930,452...39,006,220 JBrowse link
G MAOB monoamine oxidase B decreases activity EXP pralidoxime results in decreased activity of MAOB protein CTD PMID:21195145 NCBI chr  X:39,025,973...39,144,389
Ensembl chr  X:39,025,970...39,144,345 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 5152
    role 5119
      biological role 5119
        biochemical role 5043
          enzyme reactivator 3
            cholinesterase reactivator 3
              pralidoxime 3
                pralidoxime chloride 0
                pralidoxime iodide 0
                pralidoxime mesylate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 5152
    subatomic particle 5143
      composite particle 5143
        hadron 5143
          baryon 5143
            nucleon 5143
              atomic nucleus 5143
                atom 5143
                  main group element atom 5116
                    p-block element atom 5113
                      carbon group element atom 5031
                        carbon group molecular entity 5031
                          organic molecular entity 5030
                            organic ion 109
                              organic cation 92
                                pyridinium ion 3
                                  pralidoxime 3
                                    pralidoxime chloride 0
                                    pralidoxime iodide 0
                                    pralidoxime mesylate 0
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